KLRG2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vitamin transmembrane transport (GO:0035461)5.77116722
2purine nucleobase biosynthetic process (GO:0009113)5.56093237
3mitotic metaphase plate congression (GO:0007080)5.52888481
4regulation of spindle organization (GO:0090224)5.21168659
5histone arginine methylation (GO:0034969)5.08811341
6regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.08580490
7positive regulation of SMAD protein import into nucleus (GO:0060391)4.98198912
8ribosome assembly (GO:0042255)4.89169337
9regulation of posttranscriptional gene silencing (GO:0060147)4.84317049
10regulation of gene silencing by miRNA (GO:0060964)4.84317049
11regulation of gene silencing by RNA (GO:0060966)4.84317049
12nucleobase biosynthetic process (GO:0046112)4.80953731
13lung-associated mesenchyme development (GO:0060484)4.71456447
14protein complex localization (GO:0031503)4.70104819
15ribosomal small subunit assembly (GO:0000028)4.62581948
16intestinal epithelial cell development (GO:0060576)4.51856128
17regulation of mitotic spindle organization (GO:0060236)4.47583967
18hemidesmosome assembly (GO:0031581)4.24187811
19DNA unwinding involved in DNA replication (GO:0006268)4.14395165
20regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.14060039
21folic acid metabolic process (GO:0046655)4.11270123
22negative regulation of androgen receptor signaling pathway (GO:0060766)4.08038926
23ribosomal small subunit biogenesis (GO:0042274)4.04778885
24ribosome biogenesis (GO:0042254)4.03617402
25nodal signaling pathway (GO:0038092)4.02800056
26apoptotic process involved in morphogenesis (GO:0060561)3.95753577
27metaphase plate congression (GO:0051310)3.95372953
28peptidyl-arginine omega-N-methylation (GO:0035247)3.93660770
29paraxial mesoderm development (GO:0048339)3.88842196
30positive regulation of chromosome segregation (GO:0051984)3.87886078
31L-serine metabolic process (GO:0006563)3.87406525
32cellular response to interferon-alpha (GO:0035457)3.84242170
33regulation of G0 to G1 transition (GO:0070316)3.80356167
34folic acid transport (GO:0015884)3.80097203
35cranial suture morphogenesis (GO:0060363)3.76699504
36DNA replication checkpoint (GO:0000076)3.74763507
37rRNA transcription (GO:0009303)3.69050366
38regulation of SMAD protein import into nucleus (GO:0060390)3.66506139
39heterochromatin organization (GO:0070828)3.65913568
40pentose metabolic process (GO:0019321)3.64358849
41cellular protein complex localization (GO:0034629)3.60534281
42protein localization to kinetochore (GO:0034501)3.57277275
43transcription from mitochondrial promoter (GO:0006390)3.56586076
44DNA replication initiation (GO:0006270)3.53535338
45DNA strand elongation involved in DNA replication (GO:0006271)3.53290086
46regulation of stem cell maintenance (GO:2000036)3.51299006
47establishment of apical/basal cell polarity (GO:0035089)3.50955471
48regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.48991744
49regulation of exit from mitosis (GO:0007096)3.47797734
50blastocyst development (GO:0001824)3.47621698
51DNA strand elongation (GO:0022616)3.47616145
52ncRNA 3-end processing (GO:0043628)3.45902645
53histone-serine phosphorylation (GO:0035404)3.43872796
54viral transcription (GO:0019083)3.40969084
55maturation of SSU-rRNA (GO:0030490)3.39343905
56monoubiquitinated protein deubiquitination (GO:0035520)3.33516359
57termination of RNA polymerase I transcription (GO:0006363)3.32408640
58establishment of skin barrier (GO:0061436)3.31659077
59mitotic nuclear envelope disassembly (GO:0007077)3.31319269
60rRNA modification (GO:0000154)3.31046721
61regulation of water loss via skin (GO:0033561)3.30905945
62wound healing, spreading of epidermal cells (GO:0035313)3.29671583
63peptidyl-arginine N-methylation (GO:0035246)3.27700101
64peptidyl-arginine methylation (GO:0018216)3.27700101
65negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.26696049
66establishment of integrated proviral latency (GO:0075713)3.26568966
67translational termination (GO:0006415)3.25138574
68serine family amino acid biosynthetic process (GO:0009070)3.20706672
69notochord development (GO:0030903)3.19583302
70embryonic process involved in female pregnancy (GO:0060136)3.19528849
71formation of translation preinitiation complex (GO:0001731)3.19148063
72transcription elongation from RNA polymerase I promoter (GO:0006362)3.19120192
73desmosome organization (GO:0002934)3.17903184
74transcription elongation from RNA polymerase III promoter (GO:0006385)3.17345035
75termination of RNA polymerase III transcription (GO:0006386)3.17345035
76regulation of mammary gland epithelial cell proliferation (GO:0033599)3.17327825
77inner cell mass cell proliferation (GO:0001833)3.15426083
78pre-miRNA processing (GO:0031054)3.13857459
79mitochondrial RNA metabolic process (GO:0000959)3.13807808
80nuclear envelope disassembly (GO:0051081)3.12472933
81membrane disassembly (GO:0030397)3.12472933
82regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901213.12309861
83protein localization to chromosome, centromeric region (GO:0071459)3.12082812
84spindle checkpoint (GO:0031577)3.11843818
85telomere maintenance via semi-conservative replication (GO:0032201)3.10203712
86transcription from RNA polymerase I promoter (GO:0006360)3.09253989
87ribonucleoprotein complex biogenesis (GO:0022613)3.09119790
88regulation of translational fidelity (GO:0006450)3.06409283
89negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.06076056
90mitotic sister chromatid segregation (GO:0000070)3.05415798
91protein K6-linked ubiquitination (GO:0085020)3.04918838
92nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.04350913
93negative regulation of gene silencing (GO:0060969)3.02777223
94translational elongation (GO:0006414)3.02045064
95establishment of chromosome localization (GO:0051303)3.01957175
96cell fate commitment involved in formation of primary germ layer (GO:0060795)3.01790880
97regulation of mitochondrial translation (GO:0070129)3.01602116
98morphogenesis of an epithelial fold (GO:0060571)3.01518380
99maternal placenta development (GO:0001893)3.00797580
100cell migration involved in gastrulation (GO:0042074)3.00671558
101regulation of translational termination (GO:0006449)2.99941215
102molting cycle (GO:0042303)2.99847564
103hair cycle (GO:0042633)2.99847564
104regulation of chromosome segregation (GO:0051983)2.99840080
105regulation of hippo signaling (GO:0035330)2.98032934
106nuclear pore organization (GO:0006999)2.96659052
107L-alpha-amino acid transmembrane transport (GO:1902475)2.96173373
108GMP metabolic process (GO:0046037)2.95936904
109nuclear envelope organization (GO:0006998)2.94264871
110rRNA processing (GO:0006364)2.92189956
111proline biosynthetic process (GO:0006561)2.91521940
112amino sugar catabolic process (GO:0046348)2.91292661
113negative regulation of RNA splicing (GO:0033119)2.90803060
114transcription initiation from RNA polymerase I promoter (GO:0006361)2.90136464
115negative regulation of fibroblast apoptotic process (GO:2000270)2.89596871
116regulation of cell fate specification (GO:0042659)2.89410953
117pseudouridine synthesis (GO:0001522)2.87775029
118mitotic spindle checkpoint (GO:0071174)2.87715185
119rRNA metabolic process (GO:0016072)2.87066586
120determination of adult lifespan (GO:0008340)2.86867798
121ribosomal large subunit biogenesis (GO:0042273)2.84236316
122planar cell polarity pathway involved in neural tube closure (GO:0090179)2.84089703
123negative regulation of mRNA processing (GO:0050686)2.83182279
124protein maturation by protein folding (GO:0022417)2.82894401
125translational initiation (GO:0006413)2.82607335
126negative regulation of microtubule polymerization (GO:0031115)2.82136289
127pantothenate metabolic process (GO:0015939)2.79851422
128regulation of translation in response to stress (GO:0043555)2.78825034
129autophagic vacuole assembly (GO:0000045)2.77807159
130interferon-gamma secretion (GO:0072643)2.77753539
131intermediate filament organization (GO:0045109)2.77278510
132keratinocyte development (GO:0003334)2.77078040
133positive regulation of catenin import into nucleus (GO:0035413)2.76735573
134tooth mineralization (GO:0034505)2.74400358
135spindle assembly involved in mitosis (GO:0090307)2.74375228
136negative regulation of mRNA metabolic process (GO:1903312)2.74247818
137establishment of monopolar cell polarity (GO:0061162)2.73101766
138establishment or maintenance of monopolar cell polarity (GO:0061339)2.73101766
139meiosis I (GO:0007127)2.72911084
140trophectodermal cell differentiation (GO:0001829)2.72691290
141anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.72304223
142proline metabolic process (GO:0006560)2.70951075
143convergent extension (GO:0060026)2.70888447
144wound healing, spreading of cells (GO:0044319)2.70707745
145maturation of 5.8S rRNA (GO:0000460)2.70064332
146SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.69067623
147morphogenesis of embryonic epithelium (GO:0016331)2.67958343
148apoptotic process involved in development (GO:1902742)2.67814448
149protein localization to chromosome (GO:0034502)2.66202347
150skeletal muscle tissue regeneration (GO:0043403)2.65669298
151viral life cycle (GO:0019058)2.64208111
152regulation of cardioblast differentiation (GO:0051890)2.62995881
153negative regulation of chromosome segregation (GO:0051985)2.61840259
154cotranslational protein targeting to membrane (GO:0006613)2.61732402
155sphingosine metabolic process (GO:0006670)2.60341247
156protein targeting to ER (GO:0045047)2.59896509
157mitochondrial fusion (GO:0008053)2.59788317
158negative regulation of cell fate commitment (GO:0010454)2.59004369
159negative regulation by host of viral transcription (GO:0043922)2.58461735
160pore complex assembly (GO:0046931)2.58047411
161mitotic chromosome condensation (GO:0007076)2.57720666
1627-methylguanosine mRNA capping (GO:0006370)2.57327537
163regulation of mitotic metaphase/anaphase transition (GO:0030071)2.56812544
164bundle of His cell to Purkinje myocyte communication (GO:0086069)2.56203424
165polarized epithelial cell differentiation (GO:0030859)2.56101682
166nuclear pore complex assembly (GO:0051292)2.55995551
167negative regulation of epidermis development (GO:0045683)2.55605915
168positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.55472080
169regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.55320348
170sister chromatid segregation (GO:0000819)2.54627143
171mitotic spindle assembly checkpoint (GO:0007094)2.54479503
172proteasome assembly (GO:0043248)2.54438992
173microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.53250792
174primitive streak formation (GO:0090009)2.52419131
175negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.52281872
176negative regulation of sister chromatid segregation (GO:0033046)2.52281872
177negative regulation of mitotic sister chromatid separation (GO:2000816)2.52281872
178negative regulation of mitotic sister chromatid segregation (GO:0033048)2.52281872
179keratinization (GO:0031424)2.51963494
180regulation of centrosome cycle (GO:0046605)2.51338358
181regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.48847327
182positive regulation of epidermis development (GO:0045684)2.48708511
183attachment of spindle microtubules to kinetochore (GO:0008608)2.48229829
184mitotic G2 DNA damage checkpoint (GO:0007095)2.48043830

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.84245538
2E2F7_22180533_ChIP-Seq_HELA_Human5.17816225
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.23892506
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.59484004
5HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.16393861
6ZNF263_19887448_ChIP-Seq_K562_Human3.05593486
7AR_21909140_ChIP-Seq_LNCAP_Human2.97344258
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.95233169
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.64598633
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.62857989
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.62246521
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.50161602
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.45690775
14ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.34648849
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.29101160
16E2F4_17652178_ChIP-ChIP_JURKAT_Human2.22015048
17THAP11_20581084_ChIP-Seq_MESCs_Mouse2.09709016
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.07488232
19KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.03156060
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.03020746
21JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.01201891
22NANOG_18555785_ChIP-Seq_MESCs_Mouse2.00259159
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.96100274
24EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.95426614
25MYC_18358816_ChIP-ChIP_MESCs_Mouse1.92616371
26NELFA_20434984_ChIP-Seq_ESCs_Mouse1.92276983
27KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.92159603
28KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.92159603
29KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.92159603
30GABP_17652178_ChIP-ChIP_JURKAT_Human1.90042287
31CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.81352614
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.72978443
33* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.72142707
34NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.71438077
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.68612994
36STAT3_1855785_ChIP-Seq_MESCs_Mouse1.65163140
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62867997
38EST1_17652178_ChIP-ChIP_JURKAT_Human1.60949127
39POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.58244384
40VDR_23849224_ChIP-Seq_CD4+_Human1.56568020
41* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.56283323
42KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.56029800
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.54905337
44ERG_21242973_ChIP-ChIP_JURKAT_Human1.52679672
45XRN2_22483619_ChIP-Seq_HELA_Human1.52420180
46NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.51124693
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.47333407
48RARG_19884340_ChIP-ChIP_MEFs_Mouse1.45912666
49ATF3_27146783_Chip-Seq_COLON_Human1.45193208
50KDM5A_27292631_Chip-Seq_BREAST_Human1.44942781
51ELK1_22589737_ChIP-Seq_MCF10A_Human1.43132981
52NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.42895333
53E2F1_21310950_ChIP-Seq_MCF-7_Human1.42182711
54ESR1_15608294_ChIP-ChIP_MCF-7_Human1.40126149
55ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.38202835
56DCP1A_22483619_ChIP-Seq_HELA_Human1.34717348
57TET1_21451524_ChIP-Seq_MESCs_Mouse1.34632070
58E2F1_18555785_ChIP-Seq_MESCs_Mouse1.34075133
59IRF8_21731497_ChIP-ChIP_J774_Mouse1.34038802
60STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.33762190
61OCT4_18692474_ChIP-Seq_MEFs_Mouse1.31878288
62ELF1_17652178_ChIP-ChIP_JURKAT_Human1.31147045
63MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.31024819
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30945438
65LXR_22292898_ChIP-Seq_THP-1_Human1.29830330
66GABP_19822575_ChIP-Seq_HepG2_Human1.29334816
67EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.27977347
68ESR2_21235772_ChIP-Seq_MCF-7_Human1.25367768
69ZFP281_18757296_ChIP-ChIP_E14_Mouse1.25116275
70VDR_21846776_ChIP-Seq_THP-1_Human1.23588248
71SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.23572328
72SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.23490351
73NOTCH1_21737748_ChIP-Seq_TLL_Human1.23015577
74UBF1/2_26484160_Chip-Seq_HMECs_Human1.20470048
75SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.18768309
76SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.17720681
77TCF3_18692474_ChIP-Seq_MEFs_Mouse1.16248661
78POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.15715642
79TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15216218
80CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.14374345
81TP63_19390658_ChIP-ChIP_HaCaT_Human1.13045762
82SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.12736215
83SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.12736215
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11980080
85SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11432900
86POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11098591
87KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.11074558
88ESR1_21235772_ChIP-Seq_MCF-7_Human1.10717618
89P68_20966046_ChIP-Seq_HELA_Human1.10061775
90TRIM28_21343339_ChIP-Seq_HEK293_Human1.08435626
91TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.07574988
92SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.07548979
93POU5F1_16518401_ChIP-PET_MESCs_Mouse1.07368726
94CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.07286199
95DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06275605
96SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06008762
97KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.05838429
98TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.05755948
99E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04643074
100CTCF_18555785_ChIP-Seq_MESCs_Mouse1.04289814
101* FOXP1_21924763_ChIP-Seq_HESCs_Human1.03967609
102NANOG_18692474_ChIP-Seq_MEFs_Mouse1.02517680
103NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.01757658
104YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01273967
105TCF3_18692474_ChIP-Seq_MESCs_Mouse1.01116194
106ELK3_25401928_ChIP-Seq_HUVEC_Human1.00689516
107SA1_27219007_Chip-Seq_ERYTHROID_Human1.00335564
108* P63_26484246_Chip-Seq_KERATINOCYTES_Human0.99247130
109TTF2_22483619_ChIP-Seq_HELA_Human0.98973219
110BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98932340
111KAP1_27257070_Chip-Seq_ESCs_Mouse0.98532412
112SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.97946940
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97024902
114ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.96980246
115SOX2_18692474_ChIP-Seq_MESCs_Mouse0.96889689
116PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.96147034
117PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.95361459
118TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.94789873
119CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94302636
120ELK1_19687146_ChIP-ChIP_HELA_Human0.93598068
121CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.93378732
122RACK7_27058665_Chip-Seq_MCF-7_Human0.92121772
123TFEB_21752829_ChIP-Seq_HELA_Human0.90487957
124FOXP3_21729870_ChIP-Seq_TREG_Human0.88942297
125FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.88052194
126ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.87827641
127ZFX_18555785_ChIP-Seq_MESCs_Mouse0.87232284
128MYB_21317192_ChIP-Seq_ERMYB_Mouse0.86701025
129PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86480248
130HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.86377451
131FOXO3_23340844_ChIP-Seq_DLD1_Human0.86358358
132SOX2_18692474_ChIP-Seq_MEFs_Mouse0.85217508
133NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.84762314
134FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.84346368
135CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.83384249
136MYC_22102868_ChIP-Seq_BL_Human0.83324084
137CHD1_26751641_Chip-Seq_LNCaP_Human0.82876185
138KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.82656495
139NANOG_18692474_ChIP-Seq_MESCs_Mouse0.82005577
140KAP1_22055183_ChIP-Seq_ESCs_Mouse0.81601111
141* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.80153101
142UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.79972135

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.18642279
2MP0003111_abnormal_nucleus_morphology3.26388346
3MP0003705_abnormal_hypodermis_morpholog2.91591845
4MP0005275_abnormal_skin_tensile2.78059866
5MP0000383_abnormal_hair_follicle2.77459667
6MP0003718_maternal_effect2.74478827
7MP0004957_abnormal_blastocyst_morpholog2.72123850
8MP0003941_abnormal_skin_development2.66530863
9MP0002796_impaired_skin_barrier2.59919420
10MP0000579_abnormal_nail_morphology2.53203054
11MP0004233_abnormal_muscle_weight2.48390159
12MP0004264_abnormal_extraembryonic_tissu2.47823329
13MP0003077_abnormal_cell_cycle2.35598575
14MP0000566_synostosis2.26641486
15MP0010094_abnormal_chromosome_stability2.19231660
16MP0003566_abnormal_cell_adhesion2.18050568
17MP0010307_abnormal_tumor_latency2.16432254
18MP0010678_abnormal_skin_adnexa2.14945808
19MP0008260_abnormal_autophagy2.13012985
20MP0008007_abnormal_cellular_replicative2.03482228
21MP0001542_abnormal_bone_strength1.99261789
22MP0009840_abnormal_foam_cell1.99098437
23MP0010352_gastrointestinal_tract_polyps1.93609195
24MP0001216_abnormal_epidermal_layer1.87944158
25MP0003890_abnormal_embryonic-extraembry1.87354976
26MP0009672_abnormal_birth_weight1.86183644
27MP0005501_abnormal_skin_physiology1.85654893
28MP0000647_abnormal_sebaceous_gland1.83192834
29MP0004133_heterotaxia1.79412071
30MP0005451_abnormal_body_composition1.73687612
31MP0005076_abnormal_cell_differentiation1.72513347
32MP0003453_abnormal_keratinocyte_physiol1.70206985
33MP0001730_embryonic_growth_arrest1.69156615
34MP0002060_abnormal_skin_morphology1.68577271
35MP0008932_abnormal_embryonic_tissue1.65009243
36MP0002254_reproductive_system_inflammat1.60835045
37MP0008057_abnormal_DNA_replication1.57328083
38MP0002098_abnormal_vibrissa_morphology1.57195767
39MP0000350_abnormal_cell_proliferation1.55636257
40MP0003786_premature_aging1.55504155
41MP0003123_paternal_imprinting1.53027707
42MP0000678_abnormal_parathyroid_gland1.52249280
43MP0004858_abnormal_nervous_system1.50180719
44MP0000377_abnormal_hair_follicle1.48763245
45MP0000750_abnormal_muscle_regeneration1.47855524
46MP0002697_abnormal_eye_size1.47654215
47MP0003119_abnormal_digestive_system1.44967352
48MP0000462_abnormal_digestive_system1.43727011
49MP0004947_skin_inflammation1.43573496
50MP0001849_ear_inflammation1.41485153
51MP0005380_embryogenesis_phenotype1.39131670
52MP0001672_abnormal_embryogenesis/_devel1.39131670
53MP0006035_abnormal_mitochondrial_morpho1.35348887
54MP0005023_abnormal_wound_healing1.35040081
55MP0010234_abnormal_vibrissa_follicle1.34900313
56MP0002089_abnormal_postnatal_growth/wei1.34458043
57MP0000627_abnormal_mammary_gland1.33347235
58MP0005377_hearing/vestibular/ear_phenot1.33237116
59MP0003878_abnormal_ear_physiology1.33237116
60MP0003806_abnormal_nucleotide_metabolis1.31777889
61MP0009333_abnormal_splenocyte_physiolog1.30782312
62MP0008438_abnormal_cutaneous_collagen1.24777356
63MP0005395_other_phenotype1.23939624
64MP0003984_embryonic_growth_retardation1.23260205
65MP0004782_abnormal_surfactant_physiolog1.22250386
66MP0003567_abnormal_fetal_cardiomyocyte1.21310197
67MP0002088_abnormal_embryonic_growth/wei1.18521998
68MP0001243_abnormal_dermal_layer1.18327360
69MP0000049_abnormal_middle_ear1.18087431
70MP0005257_abnormal_intraocular_pressure1.17787231
71MP0002822_catalepsy1.17467337
72MP0009053_abnormal_anal_canal1.14269119
73MP0003448_altered_tumor_morphology1.12747850
74MP0004185_abnormal_adipocyte_glucose1.12277010
75MP0010771_integument_phenotype1.12259652
76MP0009379_abnormal_foot_pigmentation1.11789583
77MP0005397_hematopoietic_system_phenotyp1.11473007
78MP0001545_abnormal_hematopoietic_system1.11473007
79MP0000467_abnormal_esophagus_morphology1.10214522
80MP0002249_abnormal_larynx_morphology1.10079335
81MP0000762_abnormal_tongue_morphology1.09917586
82MP0000427_abnormal_hair_cycle1.07454769
83MP0008058_abnormal_DNA_repair1.06728553
84MP0000428_abnormal_craniofacial_morphol1.05746614
85MP0000733_abnormal_muscle_development1.04883545
86MP0003303_peritoneal_inflammation1.03599575
87MP0005508_abnormal_skeleton_morphology1.03591394
88MP0005623_abnormal_meninges_morphology1.03440048
89MP0003937_abnormal_limbs/digits/tail_de1.02195820
90MP0002080_prenatal_lethality1.01489531
91MP0005621_abnormal_cell_physiology1.01150257
92MP0009931_abnormal_skin_appearance0.97486567
93MP0000313_abnormal_cell_death0.97126328
94MP0009278_abnormal_bone_marrow0.96535237
95MP0001697_abnormal_embryo_size0.96086253
96MP0005379_endocrine/exocrine_gland_phen0.95902969
97MP0002086_abnormal_extraembryonic_tissu0.95468592
98MP0002084_abnormal_developmental_patter0.94047697
99MP0002085_abnormal_embryonic_tissue0.93960098
100MP0003861_abnormal_nervous_system0.93524781
101MP0003436_decreased_susceptibility_to0.93387823
102MP0003942_abnormal_urinary_system0.92556352
103MP0000490_abnormal_crypts_of0.91229697
104MP0001346_abnormal_lacrimal_gland0.90861690
105MP0003755_abnormal_palate_morphology0.90455722
106MP0005390_skeleton_phenotype0.90024611
107MP0003186_abnormal_redox_activity0.89771722
108MP0010030_abnormal_orbit_morphology0.88830936
109MP0000470_abnormal_stomach_morphology0.88723330
110MP0004197_abnormal_fetal_growth/weight/0.88097620
111MP0000358_abnormal_cell_content/0.87775334
112MP0002210_abnormal_sex_determination0.86595328
113MP0001533_abnormal_skeleton_physiology0.85660901
114MP0002163_abnormal_gland_morphology0.85153198
115MP0004381_abnormal_hair_follicle0.84837059
116MP0000367_abnormal_coat/_hair0.84722667
117MP0003935_abnormal_craniofacial_develop0.84333850
118MP0005670_abnormal_white_adipose0.83552446
119MP0002111_abnormal_tail_morphology0.82766434
120MP0001293_anophthalmia0.81348776
121MP0010630_abnormal_cardiac_muscle0.81143438
122MP0001191_abnormal_skin_condition0.79537988
123MP0003315_abnormal_perineum_morphology0.78851778
124MP0000432_abnormal_head_morphology0.77250498
125MP0002160_abnormal_reproductive_system0.76478026
126MP0001145_abnormal_male_reproductive0.76054425
127MP0000537_abnormal_urethra_morphology0.75640786
128MP0001881_abnormal_mammary_gland0.75354191
129MP0009703_decreased_birth_body0.73857594
130MP0002877_abnormal_melanocyte_morpholog0.71064166
131MP0005666_abnormal_adipose_tissue0.69681898
132MP0003699_abnormal_female_reproductive0.69672411
133MP0000858_altered_metastatic_potential0.69575010
134MP0002019_abnormal_tumor_incidence0.69317167
135MP0005384_cellular_phenotype0.68795676
136MP0005058_abnormal_lysosome_morphology0.67915383
137MP0003938_abnormal_ear_development0.67886935
138MP0003221_abnormal_cardiomyocyte_apopto0.66508147
139MP0004808_abnormal_hematopoietic_stem0.65977660
140MP0009384_cardiac_valve_regurgitation0.65782385
141MP0003646_muscle_fatigue0.65097187

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.32181670
2Thick nail (HP:0001805)3.73435630
3Carpal bone hypoplasia (HP:0001498)3.71830995
4Irregular epiphyses (HP:0010582)3.71696019
5Transposition of the great arteries (HP:0001669)3.63049741
6Abnormal connection of the cardiac segments (HP:0011545)3.63049741
7Abnormal ventriculo-arterial connection (HP:0011563)3.63049741
8Abnormality of the distal phalanges of the toes (HP:0010182)3.54795146
9Breast hypoplasia (HP:0003187)3.48523808
10Osteolytic defects of the hand bones (HP:0009699)3.46705955
11Osteolytic defects of the phalanges of the hand (HP:0009771)3.46705955
12Progressive muscle weakness (HP:0003323)3.45198817
13Alopecia of scalp (HP:0002293)3.43686507
14Short nail (HP:0001799)3.28461072
15Abnormality of abdominal situs (HP:0011620)3.23670513
16Abdominal situs inversus (HP:0003363)3.23670513
17Ureteral duplication (HP:0000073)3.20627149
18Pustule (HP:0200039)3.17252660
19Small epiphyses (HP:0010585)3.15982147
20Bilateral microphthalmos (HP:0007633)3.13892834
21Abnormality of cells of the erythroid lineage (HP:0012130)3.08513690
22Milia (HP:0001056)3.07851640
23Rough bone trabeculation (HP:0100670)3.07406258
24Fragile nails (HP:0001808)3.06019945
25Muscle fiber splitting (HP:0003555)3.05311866
26Abnormal number of erythroid precursors (HP:0012131)3.04066438
27Entropion (HP:0000621)2.99617680
28Sparse lateral eyebrow (HP:0005338)2.99370854
29Aplasia/Hypoplasia of the sacrum (HP:0008517)2.97199699
30Natal tooth (HP:0000695)2.96695582
31Plantar hyperkeratosis (HP:0007556)2.85533547
32Abnormality of the umbilical cord (HP:0010881)2.83992456
33Pili torti (HP:0003777)2.83666020
34Septate vagina (HP:0001153)2.81111087
35Reticulocytopenia (HP:0001896)2.80531781
36Delayed epiphyseal ossification (HP:0002663)2.80053445
37Stillbirth (HP:0003826)2.77601925
38Flat capital femoral epiphysis (HP:0003370)2.77485724
39Nail dystrophy (HP:0008404)2.77389684
40Abnormality of the proximal phalanges of the hand (HP:0009834)2.76870565
41Microvesicular hepatic steatosis (HP:0001414)2.73694445
42Partial duplication of thumb phalanx (HP:0009944)2.64956644
43Abnormality of the aortic arch (HP:0012303)2.61411984
44Submucous cleft hard palate (HP:0000176)2.60810663
45Atrophic scars (HP:0001075)2.60236554
46Birth length less than 3rd percentile (HP:0003561)2.59462719
47Amelogenesis imperfecta (HP:0000705)2.58831889
48Impulsivity (HP:0100710)2.57739415
49Choanal stenosis (HP:0000452)2.57280922
50Hyperglycinemia (HP:0002154)2.56361992
51Ankle contracture (HP:0006466)2.55734929
52Congenital malformation of the right heart (HP:0011723)2.53782913
53Double outlet right ventricle (HP:0001719)2.53782913
54Broad distal phalanx of finger (HP:0009836)2.52473708
55Premature ovarian failure (HP:0008209)2.49794584
56Abnormal trabecular bone morphology (HP:0100671)2.48971397
57Sparse eyelashes (HP:0000653)2.46422809
58Metaphyseal cupping (HP:0003021)2.43919930
59Right ventricular cardiomyopathy (HP:0011663)2.42645856
60Abnormality of the fetal cardiovascular system (HP:0010948)2.42055594
61Abnormal umbilical cord blood vessels (HP:0011403)2.42055594
62Single umbilical artery (HP:0001195)2.42055594
63Partial duplication of the phalanx of hand (HP:0009999)2.41952112
64Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.36322131
65Abnormality of nail color (HP:0100643)2.33582674
66Duplication of thumb phalanx (HP:0009942)2.33568161
67Palmoplantar hyperkeratosis (HP:0000972)2.32295405
68Spinal muscular atrophy (HP:0007269)2.31085921
69Palmar hyperkeratosis (HP:0010765)2.30825850
70Facial cleft (HP:0002006)2.29167567
71Ependymoma (HP:0002888)2.28338195
72Difficulty climbing stairs (HP:0003551)2.27529364
73Abnormality of the salivary glands (HP:0010286)2.25030285
74Aplasia/Hypoplasia of the patella (HP:0006498)2.24398172
75Patellar aplasia (HP:0006443)2.23818081
76Myopathic facies (HP:0002058)2.22732495
77Truncus arteriosus (HP:0001660)2.21639952
78Trismus (HP:0000211)2.20410418
79Pterygium (HP:0001059)2.19970893
80Areflexia of lower limbs (HP:0002522)2.19327265
81Segmental peripheral demyelination/remyelination (HP:0003481)2.18081590
82Cervical subluxation (HP:0003308)2.15423536
83Hypotrichosis (HP:0001006)2.15359378
84Genu varum (HP:0002970)2.14511310
85Microretrognathia (HP:0000308)2.13828173
86Epiphyseal dysplasia (HP:0002656)2.12968536
87Increased connective tissue (HP:0009025)2.12212486
88Prostate neoplasm (HP:0100787)2.11871179
89Atresia of the external auditory canal (HP:0000413)2.11822798
90Abnormality of the lacrimal duct (HP:0011481)2.09483707
91Congenital, generalized hypertrichosis (HP:0004540)2.08832852
92Abnormality of the labia minora (HP:0012880)2.07326451
93Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.06001953
94Absent epiphyses (HP:0010577)2.06001953
95Abnormal blistering of the skin (HP:0008066)2.05996953
96Abnormality of serine family amino acid metabolism (HP:0010894)2.03385010
97Abnormality of glycine metabolism (HP:0010895)2.03385010
98Gout (HP:0001997)2.01106587
99Patent foramen ovale (HP:0001655)2.00413981
100Short clavicles (HP:0000894)1.98615156
101Thoracolumbar scoliosis (HP:0002944)1.98445789
102Ragged-red muscle fibers (HP:0003200)1.95919315
103Cerebral hypomyelination (HP:0006808)1.95743837
104Glossoptosis (HP:0000162)1.95531653
105High anterior hairline (HP:0009890)1.94599494
106Horseshoe kidney (HP:0000085)1.93753830
107Absent radius (HP:0003974)1.93119132
108Shallow orbits (HP:0000586)1.92159443
109Chromosomal breakage induced by crosslinking agents (HP:0003221)1.91085480
110Renal agenesis (HP:0000104)1.90439432
111Hypergonadotropic hypogonadism (HP:0000815)1.90379917
112Pelvic girdle muscle weakness (HP:0003749)1.89786002
113Turricephaly (HP:0000262)1.89634776
114Advanced eruption of teeth (HP:0006288)1.88938662
115Onycholysis (HP:0001806)1.88321385
116Vaginal fistula (HP:0004320)1.88091090
117Nasolacrimal duct obstruction (HP:0000579)1.86913661
118Asplenia (HP:0001746)1.86575400
119Atrioventricular block (HP:0001678)1.85896998
120Cleft eyelid (HP:0000625)1.85075774
121Cupped ribs (HP:0000887)1.84875350
122Wrist flexion contracture (HP:0001239)1.83712077
123Hypoparathyroidism (HP:0000829)1.83477864
124Abnormality of femoral epiphyses (HP:0006499)1.82784976
125Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.82784976
126Oligodactyly (hands) (HP:0001180)1.82335909
127Hypoplastic ischia (HP:0003175)1.82001058
128Blepharitis (HP:0000498)1.81729862
129Woolly hair (HP:0002224)1.80939670
130Hypoplasia of the capital femoral epiphysis (HP:0003090)1.80795182
131Aplasia/Hypoplasia of the clavicles (HP:0006710)1.80424477
132Secondary amenorrhea (HP:0000869)1.80138295
133Abnormality of the nasolacrimal system (HP:0000614)1.80116330
134Absent forearm bone (HP:0003953)1.79137394
135Aplasia involving forearm bones (HP:0009822)1.79137394
136Selective tooth agenesis (HP:0001592)1.77841279
137Follicular hyperkeratosis (HP:0007502)1.77610884
138External ophthalmoplegia (HP:0000544)1.77608763
139Multiple enchondromatosis (HP:0005701)1.75124118
140Aplasia/Hypoplasia of the spleen (HP:0010451)1.74250475
141Death in infancy (HP:0001522)1.74149698
142Choanal atresia (HP:0000453)1.73743077
143Degeneration of anterior horn cells (HP:0002398)1.72442405
144Abnormality of the anterior horn cell (HP:0006802)1.72442405
145Abnormalities of placenta or umbilical cord (HP:0001194)1.72135352
146Chromsome breakage (HP:0040012)1.72018153
147Premature loss of primary teeth (HP:0006323)1.71456461
148Unilateral renal agenesis (HP:0000122)1.71283730
149Abnormality of the epiphysis of the femoral head (HP:0010574)1.70936268
150Coxa vara (HP:0002812)1.70755654
151Fused cervical vertebrae (HP:0002949)1.70737684
152Hyperglycinuria (HP:0003108)1.69895938
153Oligodactyly (HP:0012165)1.69102606
154Rectal fistula (HP:0100590)1.69041725
155Rectovaginal fistula (HP:0000143)1.69041725
156Hepatoblastoma (HP:0002884)1.68682510
157Abnormality of the distal phalanx of the thumb (HP:0009617)1.68571071
158Long palpebral fissure (HP:0000637)1.68136086
159Abnormality of the middle phalanges of the toes (HP:0010183)1.67392958
160Osteomalacia (HP:0002749)1.66882050
161Abnormality of the phalanges of the hallux (HP:0010057)1.66183764
162Thrombocytosis (HP:0001894)1.65656502
163Intestinal fistula (HP:0100819)1.64972178
164Acute lymphatic leukemia (HP:0006721)1.61976202
165Absent thumb (HP:0009777)1.61435339
166Hypoplastic left heart (HP:0004383)1.61278330
167Abnormality of pyrimidine metabolism (HP:0004353)1.61112747
168Dysmetric saccades (HP:0000641)1.60958016
169Abnormal lung lobation (HP:0002101)1.60397300
170Preauricular skin tag (HP:0000384)1.59794685
171Congenital ichthyosiform erythroderma (HP:0007431)1.59679702
172Reduced antithrombin III activity (HP:0001976)1.59608841
173Bicornuate uterus (HP:0000813)1.59037561
174Deviation of the thumb (HP:0009603)1.58536913

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG15.49037998
2BUB14.66674090
3VRK24.08167341
4EPHA23.97399381
5LMTK23.62522665
6NEK23.19679091
7AKT33.16150213
8WEE13.07175308
9NME23.06902673
10PIM23.00582782
11LATS12.53522935
12LATS22.49728518
13STK32.47028894
14MAP3K32.43804813
15TAF12.43591789
16BRSK22.42736057
17EIF2AK12.33731664
18PLK42.16774632
19STK38L2.02794850
20ICK1.86237015
21ARAF1.74259977
22TTK1.71491585
23STK161.64575888
24PHKG11.57852655
25PHKG21.57852655
26MKNK21.56716033
27PLK11.50673305
28CDK191.45319416
29NEK11.42961541
30ACVR1B1.42139162
31BRAF1.41015069
32PLK31.39876371
33ZAK1.39381319
34TSSK61.38607982
35EIF2AK31.35907229
36AURKB1.31353055
37RPS6KA41.30897924
38KDR1.21665007
39PDK21.21081933
40BRSK11.21028017
41STK101.19950941
42CHEK21.16922178
43CDK41.16508153
44MKNK11.15316377
45PRKCI1.14917000
46MST1R1.13026589
47TAOK11.12519357
48PIM11.10982005
49MARK31.08559660
50DYRK31.08371770
51STK241.06387540
52SRPK11.06036737
53TRIB31.05744036
54CDK121.03531230
55CDC71.03208788
56AURKA1.00771496
57MAP3K101.00539800
58PBK1.00092743
59MAP3K80.98129368
60DDR20.97398465
61CDK70.95064702
62PRPF4B0.90757678
63RAF10.90686574
64ALK0.87987247
65BLK0.84434589
66EIF2AK20.83626873
67MAP3K110.82789234
68PRKG20.80322574
69FER0.80223985
70FGFR40.78189298
71PAK10.77163038
72CHEK10.76462600
73PRKD30.76250155
74STK40.73630494
75VRK10.73215586
76DAPK10.72774344
77RPS6KA20.71960211
78RPS6KL10.71223490
79RPS6KC10.71223490
80TTN0.71205052
81MAPKAPK30.70765229
82NUAK10.67971377
83NEK90.65460836
84MAP3K50.62719930
85MTOR0.61250632
86MELK0.61120765
87NME10.61058556
88SIK10.60878735
89RPS6KA10.60360632
90TRPM70.60090388
91ABL20.59177380
92RPS6KA60.57598628
93RPS6KB20.57515221
94EEF2K0.57094223
95PASK0.56627177
96TESK10.55035883
97MAP3K90.52407722
98CDK60.52283944
99ILK0.51937061
100CAMK1D0.51370460
101TAOK20.51210450
102MATK0.50958148
103IRAK30.50547562
104DMPK0.49922921
105BMX0.49364971
106CDK20.49048921
107OXSR10.48424734
108MST40.47565326
109IKBKB0.47345935
110TYK20.46522377
111DAPK30.44800835
112ATR0.44293523
113MAPKAPK50.43278029
114CSNK2A10.40343479
115ATM0.40049311
116ERBB40.37349396
117AKT20.37204117
118MAPK110.37101987
119TESK20.36608068
120CDK90.36517219
121MUSK0.36477744
122PAK40.35903932
123BRD40.35826325
124MET0.35625223
125PAK20.34516636
126RPS6KA50.33912930
127CSNK1G30.32050342
128ZAP700.31477619
129MAP2K20.30464311
130DYRK20.30258075
131CSNK2A20.30185553
132CSNK1E0.30087221
133CCNB10.29829584
134CDK10.29432279
135FGFR10.29234048
136SCYL20.29220390
137KSR20.28296309
138GSK3B0.28050096
139PTK20.27888295
140STK380.27301337
141PRKAA10.25756616
142PDK40.25435042
143PDK30.25435042

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.76489323
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.13186728
3RNA polymerase_Homo sapiens_hsa030203.80685165
4RNA transport_Homo sapiens_hsa030132.82570818
5Cell cycle_Homo sapiens_hsa041102.60112706
6p53 signaling pathway_Homo sapiens_hsa041152.55108037
7Proteasome_Homo sapiens_hsa030502.54468153
8Folate biosynthesis_Homo sapiens_hsa007902.46741734
9Cyanoamino acid metabolism_Homo sapiens_hsa004602.35379824
10Pyrimidine metabolism_Homo sapiens_hsa002401.90163241
11Vitamin digestion and absorption_Homo sapiens_hsa049771.87710665
12Regulation of autophagy_Homo sapiens_hsa041401.74779309
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.73571678
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.73275177
15Basal transcription factors_Homo sapiens_hsa030221.70055369
16Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.69408170
17Selenocompound metabolism_Homo sapiens_hsa004501.65806016
18Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.62341697
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.52104334
20Spliceosome_Homo sapiens_hsa030401.41316008
21ECM-receptor interaction_Homo sapiens_hsa045121.39244390
22Glycerophospholipid metabolism_Homo sapiens_hsa005641.37864392
23Epstein-Barr virus infection_Homo sapiens_hsa051691.32923514
24Non-homologous end-joining_Homo sapiens_hsa034501.31095430
25Carbon metabolism_Homo sapiens_hsa012001.30976638
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.30847346
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.30269242
28Small cell lung cancer_Homo sapiens_hsa052221.27931370
29Pentose phosphate pathway_Homo sapiens_hsa000301.18888748
30DNA replication_Homo sapiens_hsa030301.18443464
31MicroRNAs in cancer_Homo sapiens_hsa052061.14247098
32Central carbon metabolism in cancer_Homo sapiens_hsa052301.11872295
33Nucleotide excision repair_Homo sapiens_hsa034201.08861348
34Fanconi anemia pathway_Homo sapiens_hsa034601.07750361
35Sulfur relay system_Homo sapiens_hsa041221.05833468
36Homologous recombination_Homo sapiens_hsa034401.05121932
37N-Glycan biosynthesis_Homo sapiens_hsa005101.04560695
38Drug metabolism - other enzymes_Homo sapiens_hsa009831.03565010
39Hippo signaling pathway_Homo sapiens_hsa043901.02324431
40Lysosome_Homo sapiens_hsa041421.02169769
41Galactose metabolism_Homo sapiens_hsa000521.02142708
42Base excision repair_Homo sapiens_hsa034101.01837181
43Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.00397347
44Fructose and mannose metabolism_Homo sapiens_hsa000511.00268340
45Apoptosis_Homo sapiens_hsa042100.99938560
46Huntingtons disease_Homo sapiens_hsa050160.99917187
47Sphingolipid metabolism_Homo sapiens_hsa006000.98867795
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.98571105
49Bladder cancer_Homo sapiens_hsa052190.98252503
50Purine metabolism_Homo sapiens_hsa002300.97689796
51Oxidative phosphorylation_Homo sapiens_hsa001900.97335049
52Ribosome_Homo sapiens_hsa030100.96253880
53Arginine and proline metabolism_Homo sapiens_hsa003300.92844606
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92310531
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91668030
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90745028
57Glutathione metabolism_Homo sapiens_hsa004800.90636175
58mRNA surveillance pathway_Homo sapiens_hsa030150.87867797
59TGF-beta signaling pathway_Homo sapiens_hsa043500.87209088
60Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.86151885
61Fatty acid elongation_Homo sapiens_hsa000620.85619019
62Oocyte meiosis_Homo sapiens_hsa041140.84502739
63Viral carcinogenesis_Homo sapiens_hsa052030.84184247
64Notch signaling pathway_Homo sapiens_hsa043300.83548747
65Parkinsons disease_Homo sapiens_hsa050120.82758081
66Herpes simplex infection_Homo sapiens_hsa051680.81688300
67Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80533999
68Wnt signaling pathway_Homo sapiens_hsa043100.77775643
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.75735996
70Proteoglycans in cancer_Homo sapiens_hsa052050.74440210
71FoxO signaling pathway_Homo sapiens_hsa040680.73589750
72One carbon pool by folate_Homo sapiens_hsa006700.73128187
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72181029
74Mismatch repair_Homo sapiens_hsa034300.70447999
75Melanoma_Homo sapiens_hsa052180.70286947
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70092202
77NOD-like receptor signaling pathway_Homo sapiens_hsa046210.70053385
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.69616393
79Influenza A_Homo sapiens_hsa051640.68894545
80Adherens junction_Homo sapiens_hsa045200.68681408
81Pyruvate metabolism_Homo sapiens_hsa006200.65738561
82Hedgehog signaling pathway_Homo sapiens_hsa043400.64453444
83mTOR signaling pathway_Homo sapiens_hsa041500.63703797
84Prostate cancer_Homo sapiens_hsa052150.61988214
85Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.61569760
86HTLV-I infection_Homo sapiens_hsa051660.61286366
87Antigen processing and presentation_Homo sapiens_hsa046120.59538474
88Intestinal immune network for IgA production_Homo sapiens_hsa046720.57213150
89Hepatitis B_Homo sapiens_hsa051610.56985149
90RNA degradation_Homo sapiens_hsa030180.56816564
91Metabolic pathways_Homo sapiens_hsa011000.56349116
92Basal cell carcinoma_Homo sapiens_hsa052170.55879512
93Vibrio cholerae infection_Homo sapiens_hsa051100.55602857
94Lysine degradation_Homo sapiens_hsa003100.54277934
95Thyroid cancer_Homo sapiens_hsa052160.53779334
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53203541
97Focal adhesion_Homo sapiens_hsa045100.53135273
98Chronic myeloid leukemia_Homo sapiens_hsa052200.52821400
99Protein digestion and absorption_Homo sapiens_hsa049740.52405249
100Amoebiasis_Homo sapiens_hsa051460.50954210
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50296871
102Toxoplasmosis_Homo sapiens_hsa051450.50264282
103Acute myeloid leukemia_Homo sapiens_hsa052210.49831470
104Arachidonic acid metabolism_Homo sapiens_hsa005900.48621785
105Tuberculosis_Homo sapiens_hsa051520.48125359
106Renal cell carcinoma_Homo sapiens_hsa052110.47929674
107Insulin signaling pathway_Homo sapiens_hsa049100.47755367
108Staphylococcus aureus infection_Homo sapiens_hsa051500.47137391
109Rheumatoid arthritis_Homo sapiens_hsa053230.46951003
110Jak-STAT signaling pathway_Homo sapiens_hsa046300.46697599
111Endometrial cancer_Homo sapiens_hsa052130.46276693
112Shigellosis_Homo sapiens_hsa051310.46031449
113Biosynthesis of amino acids_Homo sapiens_hsa012300.45630059
114Steroid biosynthesis_Homo sapiens_hsa001000.44820297
115Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44677732
116Arginine biosynthesis_Homo sapiens_hsa002200.44266087
117HIF-1 signaling pathway_Homo sapiens_hsa040660.43698690
118Tight junction_Homo sapiens_hsa045300.43670112
119Phagosome_Homo sapiens_hsa041450.43464499
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.43447304
121Legionellosis_Homo sapiens_hsa051340.43039255
122Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42062861
123Malaria_Homo sapiens_hsa051440.41967103
124Alzheimers disease_Homo sapiens_hsa050100.41719813
125AMPK signaling pathway_Homo sapiens_hsa041520.41690627
126Measles_Homo sapiens_hsa051620.41639835
127Circadian rhythm_Homo sapiens_hsa047100.41427597
128Hepatitis C_Homo sapiens_hsa051600.41133765
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.40851633
130Mineral absorption_Homo sapiens_hsa049780.40764493
131Inositol phosphate metabolism_Homo sapiens_hsa005620.39177648
132Pathways in cancer_Homo sapiens_hsa052000.38015279
133Systemic lupus erythematosus_Homo sapiens_hsa053220.37829185
134Leishmaniasis_Homo sapiens_hsa051400.37623904
135Pancreatic cancer_Homo sapiens_hsa052120.37252132
136Cysteine and methionine metabolism_Homo sapiens_hsa002700.37134393
137Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.32271619
138Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30841290
139Glucagon signaling pathway_Homo sapiens_hsa049220.29979962
140Cardiac muscle contraction_Homo sapiens_hsa042600.27963600
141Melanogenesis_Homo sapiens_hsa049160.27818387
142Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.26518274
143Collecting duct acid secretion_Homo sapiens_hsa049660.23609058
144Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19362386
145Colorectal cancer_Homo sapiens_hsa052100.19312063
146Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.18746055

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