KPNA2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)6.30275534
2protein localization to kinetochore (GO:0034501)5.97962561
3metaphase plate congression (GO:0051310)5.54120305
4regulation of spindle organization (GO:0090224)5.45270469
5attachment of spindle microtubules to kinetochore (GO:0008608)5.36930654
6protein localization to chromosome, centromeric region (GO:0071459)5.35364932
7kinetochore organization (GO:0051383)5.23707339
8mitotic sister chromatid segregation (GO:0000070)5.12898626
9establishment of chromosome localization (GO:0051303)5.08449246
10regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.03450124
11DNA ligation (GO:0006266)4.93008659
12sister chromatid segregation (GO:0000819)4.79052486
13mitotic chromosome condensation (GO:0007076)4.78144313
14kinetochore assembly (GO:0051382)4.77900628
15CENP-A containing nucleosome assembly (GO:0034080)4.70129085
16chromatin remodeling at centromere (GO:0031055)4.59700160
17regulation of mitotic spindle organization (GO:0060236)4.55029212
18mitotic nuclear envelope disassembly (GO:0007077)4.50593159
19spindle checkpoint (GO:0031577)4.45004941
20positive regulation of chromosome segregation (GO:0051984)4.40394109
21meiotic chromosome segregation (GO:0045132)4.36918354
22establishment of integrated proviral latency (GO:0075713)4.27908369
23regulation of chromosome segregation (GO:0051983)4.23778455
24DNA replication-independent nucleosome assembly (GO:0006336)4.20834557
25DNA replication-independent nucleosome organization (GO:0034724)4.20834557
26nuclear pore organization (GO:0006999)4.20495684
27nuclear envelope disassembly (GO:0051081)4.18583689
28membrane disassembly (GO:0030397)4.18583689
29histone exchange (GO:0043486)4.16447943
30DNA replication checkpoint (GO:0000076)4.12119729
31spindle assembly checkpoint (GO:0071173)4.11235927
32negative regulation of chromosome segregation (GO:0051985)4.10027428
33negative regulation of mitotic sister chromatid separation (GO:2000816)4.09988113
34negative regulation of mitotic sister chromatid segregation (GO:0033048)4.09988113
35negative regulation of mitotic metaphase/anaphase transition (GO:0045841)4.09988113
36negative regulation of sister chromatid segregation (GO:0033046)4.09988113
37nuclear pore complex assembly (GO:0051292)4.08378932
38mitotic spindle checkpoint (GO:0071174)4.06958412
39mitotic spindle assembly checkpoint (GO:0007094)4.05953390
40DNA unwinding involved in DNA replication (GO:0006268)4.03350224
41regulation of mitotic metaphase/anaphase transition (GO:0030071)4.02980964
42negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.98916945
43protein localization to chromosome (GO:0034502)3.95942097
44regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.94585223
45DNA strand elongation involved in DNA replication (GO:0006271)3.94149278
46ventricular cardiac muscle cell development (GO:0055015)3.93373295
47positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.88760304
48positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.88760304
49positive regulation of mitotic sister chromatid separation (GO:1901970)3.88760304
50chromosome segregation (GO:0007059)3.88055465
51regulation of mitotic sister chromatid separation (GO:0010965)3.82929633
52regulation of mitotic sister chromatid segregation (GO:0033047)3.82929633
53regulation of sister chromatid segregation (GO:0033045)3.82929633
54microtubule depolymerization (GO:0007019)3.78603344
55DNA strand elongation (GO:0022616)3.73492086
56DNA replication initiation (GO:0006270)3.71574957
57nucleobase biosynthetic process (GO:0046112)3.70656348
58DNA replication-dependent nucleosome assembly (GO:0006335)3.68459178
59DNA replication-dependent nucleosome organization (GO:0034723)3.68459178
60purine nucleobase biosynthetic process (GO:0009113)3.67692164
61regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.66275592
62telomere maintenance via semi-conservative replication (GO:0032201)3.65800067
63proteasome assembly (GO:0043248)3.64035800
64mitotic recombination (GO:0006312)3.57668363
65DNA double-strand break processing (GO:0000729)3.56391106
66anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.55818406
67telomere maintenance via recombination (GO:0000722)3.54015973
68histone-serine phosphorylation (GO:0035404)3.51568814
69regulation of centriole replication (GO:0046599)3.49804593
70regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.49224078
71formation of translation preinitiation complex (GO:0001731)3.43774257
72negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.43207995
73negative regulation of ligase activity (GO:0051352)3.43207995
74regulation of mitotic spindle checkpoint (GO:1903504)3.42307508
75regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.42307508
76mitotic G2/M transition checkpoint (GO:0044818)3.41793828
77regulation of centrosome cycle (GO:0046605)3.38421971
78negative regulation of cell division (GO:0051782)3.36355093
79ribosome biogenesis (GO:0042254)3.34486184
80chromosome condensation (GO:0030261)3.34278945
81regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.32302565
82double-strand break repair via nonhomologous end joining (GO:0006303)3.31903873
83non-recombinational repair (GO:0000726)3.31903873
84nuclear envelope organization (GO:0006998)3.27357578
85ATP-dependent chromatin remodeling (GO:0043044)3.26460322
86establishment of viral latency (GO:0019043)3.25459539
87negative regulation of DNA-dependent DNA replication (GO:2000104)3.25100330
88ribosome assembly (GO:0042255)3.24978410
89negative regulation of proteasomal protein catabolic process (GO:1901799)3.24414901
90protein complex localization (GO:0031503)3.21190539
91pore complex assembly (GO:0046931)3.20079054
92chromatin assembly or disassembly (GO:0006333)3.20063853
93positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.20044409
94negative regulation of mitosis (GO:0045839)3.19870897
95mitotic spindle organization (GO:0007052)3.18117659
96DNA topological change (GO:0006265)3.17931853
97replication fork processing (GO:0031297)3.17464036
98regulation of sister chromatid cohesion (GO:0007063)3.15697263
99maturation of SSU-rRNA (GO:0030490)3.15318070
100mitotic cell cycle (GO:0000278)3.14429374
101regulation of exit from mitosis (GO:0007096)3.12677501
102spliceosomal snRNP assembly (GO:0000387)3.10565444
103mitotic sister chromatid cohesion (GO:0007064)3.09811119
104telomere maintenance via telomere lengthening (GO:0010833)3.09684150
105regulation of ubiquitin-protein transferase activity (GO:0051438)3.07200855
106negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.07163002
107regulation of double-strand break repair via homologous recombination (GO:0010569)3.05894927
108maturation of 5.8S rRNA (GO:0000460)3.05868259
109DNA packaging (GO:0006323)3.05374141
110IMP biosynthetic process (GO:0006188)3.02967964
111protein K6-linked ubiquitination (GO:0085020)3.02859821
112resolution of meiotic recombination intermediates (GO:0000712)3.02735646
113negative regulation of DNA recombination (GO:0045910)2.99656108
114regulation of DNA endoreduplication (GO:0032875)2.97619476
115mitotic cell cycle checkpoint (GO:0007093)2.97239280
116nucleotide-excision repair, DNA gap filling (GO:0006297)2.93919370
117negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.92318799
118synaptonemal complex assembly (GO:0007130)2.91021836
119positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.88227675
120mitotic nuclear division (GO:0007067)2.85832937
121negative regulation of nuclear division (GO:0051784)2.85386382
122piRNA metabolic process (GO:0034587)2.85073700
123cell cycle G1/S phase transition (GO:0044843)2.84910006
124G1/S transition of mitotic cell cycle (GO:0000082)2.84910006

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.30467768
2* FOXM1_23109430_ChIP-Seq_U2OS_Human6.77972939
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.45863355
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.27523414
5* MYC_18555785_ChIP-Seq_MESCs_Mouse3.88129026
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.52941476
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.45797703
8* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.17433353
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.99676858
10AR_21909140_ChIP-Seq_LNCAP_Human2.88301160
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.83883614
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.78263176
13* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.73016858
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.66908588
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.64620047
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.63229376
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.57606739
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.40635153
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36919019
20XRN2_22483619_ChIP-Seq_HELA_Human2.27168446
21* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.20490693
22VDR_23849224_ChIP-Seq_CD4+_Human2.17844899
23* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.17303782
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.14210714
25* E2F1_21310950_ChIP-Seq_MCF-7_Human2.10482459
26NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.03706840
27MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96748824
28FOXP3_21729870_ChIP-Seq_TREG_Human1.95121739
29DCP1A_22483619_ChIP-Seq_HELA_Human1.94836864
30* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.94216917
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.92158351
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.89106864
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.84223585
34EGR1_19374776_ChIP-ChIP_THP-1_Human1.83563661
35* GABP_19822575_ChIP-Seq_HepG2_Human1.79861463
36TTF2_22483619_ChIP-Seq_HELA_Human1.73201711
37ELK1_19687146_ChIP-ChIP_HELA_Human1.71540207
38HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.66841027
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65794345
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64332403
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64222179
42THAP11_20581084_ChIP-Seq_MESCs_Mouse1.64186864
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.59522335
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.55442115
45CIITA_25753668_ChIP-Seq_RAJI_Human1.54960941
46KDM5A_27292631_Chip-Seq_BREAST_Human1.53343493
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.51702074
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.48882532
49RBPJ_22232070_ChIP-Seq_NCS_Mouse1.45961745
50PADI4_21655091_ChIP-ChIP_MCF-7_Human1.45100492
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.44916665
52* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.43042612
53TP63_19390658_ChIP-ChIP_HaCaT_Human1.32451896
54POU5F1_16153702_ChIP-ChIP_HESCs_Human1.32411237
55YY1_21170310_ChIP-Seq_MESCs_Mouse1.32253316
56ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30610085
57E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.26540780
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26034656
59SOX2_16153702_ChIP-ChIP_HESCs_Human1.26031723
60ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.25162395
61SRF_21415370_ChIP-Seq_HL-1_Mouse1.22753106
62SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.19443657
63TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.19323515
64* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.17531454
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.16834463
66* EWS_26573619_Chip-Seq_HEK293_Human1.16774901
67KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12793507
68* MYC_22102868_ChIP-Seq_BL_Human1.11045027
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09771759
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05979868
71SALL1_21062744_ChIP-ChIP_HESCs_Human1.05249981
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.04677976
73MYC_18940864_ChIP-ChIP_HL60_Human1.02857061
74CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.02103697
75SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00934184
76TFEB_21752829_ChIP-Seq_HELA_Human1.00813880
77ERG_20887958_ChIP-Seq_HPC-7_Mouse1.00607917
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.00384184
79NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.99886599
80POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98817609
81DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.96574145
82* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94966698
83FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.93869143
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.89694753
85FUS_26573619_Chip-Seq_HEK293_Human0.87331181
86NANOG_21062744_ChIP-ChIP_HESCs_Human0.87272245
87* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87039840
88CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86476956
89NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85287045
90SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.84669238
91KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.83922749
92BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.82514944
93* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.81413761
94SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.79743702
95* SPI1_23547873_ChIP-Seq_NB4_Human0.78331532
96ELK1_22589737_ChIP-Seq_MCF10A_Human0.77413636
97PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.76811348
98NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.76557638
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.76069979
100TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.75327770
101KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.73815135
102TCF3_18692474_ChIP-Seq_MEFs_Mouse0.73319803
103IRF1_19129219_ChIP-ChIP_H3396_Human0.73245950
104VDR_22108803_ChIP-Seq_LS180_Human0.72292783
105GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.71723940
106ZNF274_21170338_ChIP-Seq_K562_Hela0.71397836
107* SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.71256755
108* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.70812590
109SOX17_20123909_ChIP-Seq_XEN_Mouse0.69958113
110CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.69488053
111ESR1_15608294_ChIP-ChIP_MCF-7_Human0.68758372
112GATA1_26923725_Chip-Seq_HPCs_Mouse0.67943986
113KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.67767069
114KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.67767069
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.67767069
116NOTCH1_21737748_ChIP-Seq_TLL_Human0.66574548
117FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.63614653
118SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.63092730
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.62872733
120DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.62365936

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.44800774
2MP0003111_abnormal_nucleus_morphology5.26760409
3MP0010094_abnormal_chromosome_stability5.05931638
4MP0004957_abnormal_blastocyst_morpholog4.56457446
5MP0003077_abnormal_cell_cycle4.54705053
6MP0008057_abnormal_DNA_replication4.02008423
7MP0008058_abnormal_DNA_repair3.44696282
8MP0008877_abnormal_DNA_methylation3.22209795
9MP0008007_abnormal_cellular_replicative3.21732454
10MP0008932_abnormal_embryonic_tissue2.74406735
11MP0001730_embryonic_growth_arrest2.55324174
12MP0003123_paternal_imprinting2.51351900
13MP0000350_abnormal_cell_proliferation2.33306376
14MP0003786_premature_aging2.27989486
15MP0003718_maternal_effect2.23729980
16MP0009697_abnormal_copulation2.22802410
17MP0010307_abnormal_tumor_latency2.13466175
18MP0002396_abnormal_hematopoietic_system1.89261174
19MP0001672_abnormal_embryogenesis/_devel1.82876407
20MP0005380_embryogenesis_phenotype1.82876407
21MP0001697_abnormal_embryo_size1.80261725
22MP0002210_abnormal_sex_determination1.79322091
23MP0001929_abnormal_gametogenesis1.63840335
24MP0000372_irregular_coat_pigmentation1.62306790
25MP0010352_gastrointestinal_tract_polyps1.61226837
26MP0003984_embryonic_growth_retardation1.61074160
27MP0002080_prenatal_lethality1.60023716
28MP0002088_abnormal_embryonic_growth/wei1.56947188
29MP0001145_abnormal_male_reproductive1.52920067
30MP0002085_abnormal_embryonic_tissue1.52215641
31MP0003136_yellow_coat_color1.49570303
32MP0004808_abnormal_hematopoietic_stem1.44400016
33MP0000313_abnormal_cell_death1.43637005
34MP0005076_abnormal_cell_differentiation1.42309798
35MP0001529_abnormal_vocalization1.41211872
36MP0002019_abnormal_tumor_incidence1.38734009
37MP0000653_abnormal_sex_gland1.37567610
38MP0010030_abnormal_orbit_morphology1.34110725
39MP0003121_genomic_imprinting1.30526698
40MP0002084_abnormal_developmental_patter1.30174632
41MP0002086_abnormal_extraembryonic_tissu1.29866577
42MP0008789_abnormal_olfactory_epithelium1.27406493
43MP0000490_abnormal_crypts_of1.25387822
44MP0004197_abnormal_fetal_growth/weight/1.22067070
45MP0002697_abnormal_eye_size1.19225956
46MP0006292_abnormal_olfactory_placode1.16390472
47MP0003567_abnormal_fetal_cardiomyocyte1.15618753
48MP0002233_abnormal_nose_morphology1.14092682
49MP0009053_abnormal_anal_canal1.12594190
50MP0009333_abnormal_splenocyte_physiolog1.11647517
51MP0006035_abnormal_mitochondrial_morpho1.10762958
52MP0003315_abnormal_perineum_morphology1.10362833
53MP0003890_abnormal_embryonic-extraembry1.09209985
54MP0005171_absent_coat_pigmentation1.08457281
55MP0001346_abnormal_lacrimal_gland1.07923973
56MP0000566_synostosis1.07279963
57MP0001119_abnormal_female_reproductive1.05755107
58MP0001293_anophthalmia1.05562265
59MP0009672_abnormal_birth_weight1.01045653
60MP0003698_abnormal_male_reproductive0.99035717
61MP0008995_early_reproductive_senescence0.98370107
62MP0006054_spinal_hemorrhage0.96579932
63MP0005394_taste/olfaction_phenotype0.94359984
64MP0005499_abnormal_olfactory_system0.94359984
65MP0002751_abnormal_autonomic_nervous0.93223178
66MP0000049_abnormal_middle_ear0.91875409
67MP0003755_abnormal_palate_morphology0.91521881
68MP0000537_abnormal_urethra_morphology0.90666848
69MP0000647_abnormal_sebaceous_gland0.90057632
70MP0005397_hematopoietic_system_phenotyp0.88721465
71MP0001545_abnormal_hematopoietic_system0.88721465
72MP0005248_abnormal_Harderian_gland0.88504348
73MP0000703_abnormal_thymus_morphology0.87933700
74MP0000579_abnormal_nail_morphology0.87797691
75MP0003937_abnormal_limbs/digits/tail_de0.85998838
76MP0006036_abnormal_mitochondrial_physio0.85108331
77MP0003861_abnormal_nervous_system0.82297278
78MP0002161_abnormal_fertility/fecundity0.80968934
79MP0002398_abnormal_bone_marrow0.79099728
80MP0005384_cellular_phenotype0.79022868
81MP0005621_abnormal_cell_physiology0.78989010
82MP0002722_abnormal_immune_system0.77750796
83MP0003221_abnormal_cardiomyocyte_apopto0.77612478
84MP0002160_abnormal_reproductive_system0.77006956
85MP0001188_hyperpigmentation0.76910041
86MP0002234_abnormal_pharynx_morphology0.73817046
87MP0004264_abnormal_extraembryonic_tissu0.72950642
88MP0005389_reproductive_system_phenotype0.72836175
89MP0000689_abnormal_spleen_morphology0.72663712
90MP0000358_abnormal_cell_content/0.72071566
91MP0003699_abnormal_female_reproductive0.70383924
92MP0009703_decreased_birth_body0.70240558
93MP0004133_heterotaxia0.69897760
94MP0001177_atelectasis0.66808953
95MP0003935_abnormal_craniofacial_develop0.65114171
96MP0002090_abnormal_vision0.64853950
97MP0002111_abnormal_tail_morphology0.64825950
98MP0001915_intracranial_hemorrhage0.64252499
99MP0003763_abnormal_thymus_physiology0.63700421
100MP0002132_abnormal_respiratory_system0.62323915
101MP0000432_abnormal_head_morphology0.62091648
102MP0002653_abnormal_ependyma_morphology0.62054563
103MP0003941_abnormal_skin_development0.61969444
104MP0002092_abnormal_eye_morphology0.61800299
105MP0005395_other_phenotype0.61021557
106MP0002429_abnormal_blood_cell0.60499117
107MP0001299_abnormal_eye_distance/0.60338581
108MP0000383_abnormal_hair_follicle0.60326776
109MP0000858_altered_metastatic_potential0.59432708
110MP0001286_abnormal_eye_development0.58958159
111MP0001727_abnormal_embryo_implantation0.57745344
112MP0005253_abnormal_eye_physiology0.57660523
113MP0000428_abnormal_craniofacial_morphol0.57525564
114MP0003950_abnormal_plasma_membrane0.56872470
115MP0003119_abnormal_digestive_system0.55578211
116MP0001324_abnormal_eye_pigmentation0.55062559
117MP0003806_abnormal_nucleotide_metabolis0.54512454
118MP0005391_vision/eye_phenotype0.54510280
119MP0005023_abnormal_wound_healing0.54509194
120MP0003705_abnormal_hypodermis_morpholog0.52675951
121MP0002102_abnormal_ear_morphology0.52416993
122MP0006072_abnormal_retinal_apoptosis0.50388275
123MP0003115_abnormal_respiratory_system0.49553547
124MP0001764_abnormal_homeostasis0.49526736
125MP0003943_abnormal_hepatobiliary_system0.47694842
126MP0002938_white_spotting0.46655151
127MP0001919_abnormal_reproductive_system0.46485043
128MP0000716_abnormal_immune_system0.46436599
129MP0005408_hypopigmentation0.45740659
130MP0005410_abnormal_fertilization0.44947777
131MP0003186_abnormal_redox_activity0.44934171

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.60234836
2Chromsome breakage (HP:0040012)4.26299633
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.05080895
4Cortical dysplasia (HP:0002539)3.99731408
5Breast hypoplasia (HP:0003187)3.96130544
6Carpal bone hypoplasia (HP:0001498)3.94325696
7Impulsivity (HP:0100710)3.88333416
8Patellar aplasia (HP:0006443)3.78851389
9Abnormality of the anterior horn cell (HP:0006802)3.67961680
10Degeneration of anterior horn cells (HP:0002398)3.67961680
11Aplasia/Hypoplasia of the patella (HP:0006498)3.56879049
12Abnormal lung lobation (HP:0002101)3.42624064
13Meckel diverticulum (HP:0002245)3.40243554
14Abnormality of chromosome stability (HP:0003220)3.38465825
15Small intestinal stenosis (HP:0012848)3.32908788
16Duodenal stenosis (HP:0100867)3.32908788
17Abnormality of the preputium (HP:0100587)3.28266374
18Abnormality of the ileum (HP:0001549)3.18869650
19Oral leukoplakia (HP:0002745)3.11422080
20Aplasia/Hypoplasia of the uvula (HP:0010293)3.05842364
21Abnormality of the labia minora (HP:0012880)3.00781474
22Colon cancer (HP:0003003)2.92307870
23Selective tooth agenesis (HP:0001592)2.91355558
2411 pairs of ribs (HP:0000878)2.91304731
25Reticulocytopenia (HP:0001896)2.88665830
26Sloping forehead (HP:0000340)2.87748602
27Myelodysplasia (HP:0002863)2.81613649
28Abnormal spermatogenesis (HP:0008669)2.80449731
29Medulloblastoma (HP:0002885)2.79013487
30Hypoplasia of the capital femoral epiphysis (HP:0003090)2.76444177
31Increased nuchal translucency (HP:0010880)2.76166783
32Rough bone trabeculation (HP:0100670)2.74213672
33Absent radius (HP:0003974)2.71894052
34Facial hemangioma (HP:0000329)2.69341640
35Abnormality of the duodenum (HP:0002246)2.68453515
36Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.64890214
37Cerebral hypomyelination (HP:0006808)2.59626901
38Aplasia/Hypoplasia of the sacrum (HP:0008517)2.57802761
39Ectopic kidney (HP:0000086)2.57035147
40Bone marrow hypocellularity (HP:0005528)2.54676269
41Absent thumb (HP:0009777)2.54392143
42Aplasia involving forearm bones (HP:0009822)2.51441866
43Absent forearm bone (HP:0003953)2.51441866
44Nephroblastoma (Wilms tumor) (HP:0002667)2.46308095
45Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.45904863
46Short 4th metacarpal (HP:0010044)2.45904863
47Supernumerary spleens (HP:0009799)2.40647778
48Horseshoe kidney (HP:0000085)2.37593831
49Embryonal neoplasm (HP:0002898)2.36293640
50Agnosia (HP:0010524)2.34124161
51Hypoplastic pelvis (HP:0008839)2.33395098
52Glioma (HP:0009733)2.32844460
53Pendular nystagmus (HP:0012043)2.32732362
54Abnormality of glycolysis (HP:0004366)2.32056594
55Neoplasm of the pancreas (HP:0002894)2.31071416
56Embryonal renal neoplasm (HP:0011794)2.30005172
57Abnormality of the fetal cardiovascular system (HP:0010948)2.28803893
58Abnormal umbilical cord blood vessels (HP:0011403)2.28803893
59Single umbilical artery (HP:0001195)2.28803893
60Aplastic anemia (HP:0001915)2.26083361
61Atrophy/Degeneration involving motor neurons (HP:0007373)2.24487011
62Neoplasm of the colon (HP:0100273)2.24297165
63Volvulus (HP:0002580)2.21257940
64Increased serum pyruvate (HP:0003542)2.20522312
65Tracheoesophageal fistula (HP:0002575)2.19066335
66Rhabdomyosarcoma (HP:0002859)2.18553866
67Ependymoma (HP:0002888)2.18090355
68Cafe-au-lait spot (HP:0000957)2.17505118
69Premature ovarian failure (HP:0008209)2.15645881
70Proximal placement of thumb (HP:0009623)2.15431987
71Deviation of the thumb (HP:0009603)2.13138768
72Short thumb (HP:0009778)2.11521429
73Astrocytoma (HP:0009592)2.10827017
74Abnormality of the astrocytes (HP:0100707)2.10827017
75Premature graying of hair (HP:0002216)2.10572400
76Atresia of the external auditory canal (HP:0000413)2.10064120
77Abnormality of cells of the erythroid lineage (HP:0012130)2.09569751
78Aplasia/Hypoplasia of the sternum (HP:0006714)2.06727991
79Secondary amenorrhea (HP:0000869)2.06095916
80Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.05836971
81Absent epiphyses (HP:0010577)2.05836971
82Abnormal number of erythroid precursors (HP:0012131)2.05057334
83Cleft eyelid (HP:0000625)2.02985395
84Cellular immunodeficiency (HP:0005374)2.02554836
85Choanal atresia (HP:0000453)2.02286382
86Abnormality of the carotid arteries (HP:0005344)2.01260386
87Duplicated collecting system (HP:0000081)2.01134095
88Abnormality of the umbilical cord (HP:0010881)2.01030742
89Multiple enchondromatosis (HP:0005701)1.99938156
90Microretrognathia (HP:0000308)1.99196827
91Squamous cell carcinoma (HP:0002860)1.96940344
92Absent septum pellucidum (HP:0001331)1.95915676
93Abnormal trabecular bone morphology (HP:0100671)1.95216455
94Trismus (HP:0000211)1.94908041
95Ureteral duplication (HP:0000073)1.94691328
96Abnormality of the septum pellucidum (HP:0007375)1.94221464
97Abnormal number of incisors (HP:0011064)1.93758105
98Abnormality of the calcaneus (HP:0008364)1.93594200
99Oligodactyly (HP:0012165)1.91695107
100Azoospermia (HP:0000027)1.90938979
101Basal cell carcinoma (HP:0002671)1.90152039
102Prominent nose (HP:0000448)1.90064641
103Triphalangeal thumb (HP:0001199)1.89632905
104Cutaneous melanoma (HP:0012056)1.88965313
105Facial cleft (HP:0002006)1.87050317
106High pitched voice (HP:0001620)1.85873674
107Intestinal atresia (HP:0011100)1.85678773
108Abnormality of methionine metabolism (HP:0010901)1.85655747
109Missing ribs (HP:0000921)1.83084635
110Irregular epiphyses (HP:0010582)1.81572588
111Pancreatic islet-cell hyperplasia (HP:0004510)1.80798416
112Neoplasm of the adrenal gland (HP:0100631)1.79553032
113Intestinal polyposis (HP:0200008)1.78783092
114Septo-optic dysplasia (HP:0100842)1.77404472
115Clubbing of toes (HP:0100760)1.76938291
116Entropion (HP:0000621)1.76892172
117Small epiphyses (HP:0010585)1.76167803
118Spinal muscular atrophy (HP:0007269)1.75813654
119Aplasia/Hypoplasia of the earlobes (HP:0009906)1.75436430
120Ovarian neoplasm (HP:0100615)1.75163351
121Dandy-Walker malformation (HP:0001305)1.73934914
122Broad distal phalanx of finger (HP:0009836)1.73912483
123Capillary hemangiomas (HP:0005306)1.73695288
124Glossoptosis (HP:0000162)1.73432453
125Microvesicular hepatic steatosis (HP:0001414)1.72988092
126Neoplasm of striated muscle (HP:0009728)1.67659084
127Bifid tongue (HP:0010297)1.67615535
128Arteriovenous malformation (HP:0100026)1.67285430
129Intestinal polyp (HP:0005266)1.65483191
130Spastic diplegia (HP:0001264)1.64311863
131Postnatal microcephaly (HP:0005484)1.64132628
132Preaxial hand polydactyly (HP:0001177)1.63841510
133Breast carcinoma (HP:0003002)1.62919121
134Acute encephalopathy (HP:0006846)1.62754211
135Oligodactyly (hands) (HP:0001180)1.60312422
136Median cleft lip (HP:0000161)1.58748348
137Acute necrotizing encephalopathy (HP:0006965)1.57430614
138Abnormality of serum amino acid levels (HP:0003112)1.57220370
139Abnormality of chromosome segregation (HP:0002916)1.55199593
140Holoprosencephaly (HP:0001360)1.55099918
141Small hand (HP:0200055)1.54083379
142Abnormality of aspartate family amino acid metabolism (HP:0010899)1.52009550
143Type I transferrin isoform profile (HP:0003642)1.51966217

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB16.54926029
2WEE14.67130978
3CDC73.76295156
4NEK23.29968857
5BRSK23.18127543
6EIF2AK12.86767247
7TTK2.86094265
8NEK12.68823665
9PLK42.47862659
10PLK12.39717540
11ACVR1B2.37645094
12SRPK12.34039324
13TRIM282.29647293
14CCNB12.19058280
15PLK32.17340222
16BRSK12.16922515
17TSSK62.10587577
18AURKB1.92243440
19VRK21.84690132
20STK161.80683515
21MKNK11.71736236
22TESK21.65786147
23EIF2AK31.57498098
24PBK1.56967854
25CHEK21.49984830
26VRK11.49030221
27STK101.48984814
28ATR1.45312233
29AURKA1.39958981
30RPS6KA41.39246539
31MKNK21.37185036
32MAP3K81.34206795
33CDK71.34134225
34TNIK1.32535965
35WNK31.30806112
36STK41.28223619
37DYRK31.24930148
38* CHEK11.16784777
39PDK41.16519485
40PDK31.16519485
41TAF11.16253849
42PASK1.12651155
43CDK41.09228795
44MELK1.02221138
45CDK121.00600206
46ZAK0.99949388
47TESK10.98377497
48STK30.96717047
49TLK10.92843018
50EIF2AK20.91925376
51RPS6KB20.91032564
52NME20.86363452
53ATM0.84719019
54BRAF0.84650402
55PAK40.83218080
56STK38L0.82874870
57BCR0.81776770
58TGFBR10.81500487
59CDK20.75025241
60CLK10.73505693
61CDK10.71440566
62BMPR1B0.70307845
63EPHA20.69819245
64PAK10.64775767
65EEF2K0.64330091
66PDK20.61446629
67CDK80.60224136
68CSNK2A10.55925063
69PNCK0.53747656
70CDK60.52564150
71MST40.52459401
72PIM10.50956050
73ERBB40.48901962
74MARK30.48778684
75PRKCI0.48189337
76CSNK1G10.47516197
77LATS10.47253084
78UHMK10.46792386
79CSNK2A20.45874532
80LIMK10.43778521
81SCYL20.43337079
82LATS20.42561502
83SIK30.40393049
84DYRK20.39405304
85FGFR10.38804871
86MAP3K100.37963277
87CSNK1G30.37877737
88MAP4K10.37752678
89MINK10.37371447
90LRRK20.36804335
91ALK0.35551513
92CDK30.30464014
93KDR0.29566756
94CDK140.29200143
95CSNK1G20.28265319
96BRD40.27742225
97BLK0.26759169
98RPS6KA50.26070637
99NUAK10.25398280
100STK240.25213842
101CSNK1A1L0.24882166
102MST1R0.24548937
103NEK90.23983774
104MET0.22268232
105PRKDC0.21943386
106CDK90.21594037
107PKN20.20872222
108SMG10.20136590
109AKT20.17788616
110CSNK1E0.17061634
111MAPK140.16638928
112PRKCG0.16345672
113MAP4K20.16028483
114MAP3K120.15417006
115MAPKAPK20.14892472
116MTOR0.14353266
117IRAK40.12714320
118NME10.12350410
119CDK180.11505207
120PIM20.11471627
121CDK150.11466277
122PLK20.11157953
123CDK11A0.10387853
124GSK3B0.10154142
125FLT30.09244333
126ERBB30.08890510

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.44712388
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.01687274
3Mismatch repair_Homo sapiens_hsa034303.95964222
4RNA transport_Homo sapiens_hsa030133.53676517
5Cell cycle_Homo sapiens_hsa041103.50175314
6RNA polymerase_Homo sapiens_hsa030203.40192889
7Spliceosome_Homo sapiens_hsa030403.36965963
8Proteasome_Homo sapiens_hsa030503.30464120
9Homologous recombination_Homo sapiens_hsa034403.12634723
10Base excision repair_Homo sapiens_hsa034102.99075324
11Nucleotide excision repair_Homo sapiens_hsa034202.81395136
12Fanconi anemia pathway_Homo sapiens_hsa034602.51943783
13Basal transcription factors_Homo sapiens_hsa030222.46230576
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.35693887
15Pyrimidine metabolism_Homo sapiens_hsa002402.33510409
16Ribosome_Homo sapiens_hsa030102.15637888
17One carbon pool by folate_Homo sapiens_hsa006702.15553272
18Non-homologous end-joining_Homo sapiens_hsa034502.06250027
19RNA degradation_Homo sapiens_hsa030182.03995411
20Vitamin B6 metabolism_Homo sapiens_hsa007501.98485640
21p53 signaling pathway_Homo sapiens_hsa041151.97399279
22mRNA surveillance pathway_Homo sapiens_hsa030151.97357400
23Oocyte meiosis_Homo sapiens_hsa041141.66304288
24Steroid biosynthesis_Homo sapiens_hsa001001.57282885
25Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.48635322
26Purine metabolism_Homo sapiens_hsa002301.39094155
27Epstein-Barr virus infection_Homo sapiens_hsa051691.35392094
28Propanoate metabolism_Homo sapiens_hsa006401.30527059
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.18748103
30Fatty acid elongation_Homo sapiens_hsa000621.13521980
31Systemic lupus erythematosus_Homo sapiens_hsa053221.12301045
32Pentose phosphate pathway_Homo sapiens_hsa000301.09301366
33Parkinsons disease_Homo sapiens_hsa050121.08568099
34Viral carcinogenesis_Homo sapiens_hsa052031.02261039
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.02116299
36Selenocompound metabolism_Homo sapiens_hsa004500.98757501
37Cysteine and methionine metabolism_Homo sapiens_hsa002700.95372491
38Biosynthesis of amino acids_Homo sapiens_hsa012300.92238132
39Oxidative phosphorylation_Homo sapiens_hsa001900.91885911
40Herpes simplex infection_Homo sapiens_hsa051680.91618041
41Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.91158764
42Phototransduction_Homo sapiens_hsa047440.87853738
43Antigen processing and presentation_Homo sapiens_hsa046120.87195153
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83234471
45HTLV-I infection_Homo sapiens_hsa051660.79642444
46Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79620530
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.79594354
48Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.73234472
49MicroRNAs in cancer_Homo sapiens_hsa052060.68650667
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63622290
51Drug metabolism - other enzymes_Homo sapiens_hsa009830.62753689
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.61729131
53Legionellosis_Homo sapiens_hsa051340.59798198
54Protein export_Homo sapiens_hsa030600.58004125
55Small cell lung cancer_Homo sapiens_hsa052220.54854680
56Carbon metabolism_Homo sapiens_hsa012000.53671129
57Lysine degradation_Homo sapiens_hsa003100.53422125
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52321075
59Thyroid cancer_Homo sapiens_hsa052160.50871839
60Glutathione metabolism_Homo sapiens_hsa004800.49334106
61Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48979880
62Cyanoamino acid metabolism_Homo sapiens_hsa004600.48568555
63Alzheimers disease_Homo sapiens_hsa050100.45942673
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45572746
65Folate biosynthesis_Homo sapiens_hsa007900.45414962
66Wnt signaling pathway_Homo sapiens_hsa043100.44507747
67Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44340076
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.44209701
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41872587
70Arginine and proline metabolism_Homo sapiens_hsa003300.41167475
71Sulfur relay system_Homo sapiens_hsa041220.40825597
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39795949
73Apoptosis_Homo sapiens_hsa042100.39406533
74Fatty acid metabolism_Homo sapiens_hsa012120.38350689
75Huntingtons disease_Homo sapiens_hsa050160.38038119
76Hippo signaling pathway_Homo sapiens_hsa043900.35892073
77TGF-beta signaling pathway_Homo sapiens_hsa043500.35480447
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35334967
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35016966
80Colorectal cancer_Homo sapiens_hsa052100.34155486
81Fructose and mannose metabolism_Homo sapiens_hsa000510.32654746
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32314333
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31170598
84Alcoholism_Homo sapiens_hsa050340.30144359
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29146504
86N-Glycan biosynthesis_Homo sapiens_hsa005100.28723764
87Regulation of autophagy_Homo sapiens_hsa041400.28601306
88Shigellosis_Homo sapiens_hsa051310.27856780
89Primary immunodeficiency_Homo sapiens_hsa053400.27819152
90Hepatitis B_Homo sapiens_hsa051610.26812907
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.26057124
92Viral myocarditis_Homo sapiens_hsa054160.25317660
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.24375312
94HIF-1 signaling pathway_Homo sapiens_hsa040660.24007203
95Tight junction_Homo sapiens_hsa045300.23642804
96FoxO signaling pathway_Homo sapiens_hsa040680.22950790
97Sulfur metabolism_Homo sapiens_hsa009200.22432223
98beta-Alanine metabolism_Homo sapiens_hsa004100.22134979
99Basal cell carcinoma_Homo sapiens_hsa052170.21140986
100Measles_Homo sapiens_hsa051620.20732598
101NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18077747
1022-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.17816795
103NF-kappa B signaling pathway_Homo sapiens_hsa040640.17485599
104* Influenza A_Homo sapiens_hsa051640.17002904
105Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.15227297
106Butanoate metabolism_Homo sapiens_hsa006500.14940233
107Metabolic pathways_Homo sapiens_hsa011000.14855346
108Renin-angiotensin system_Homo sapiens_hsa046140.14562149
109Vitamin digestion and absorption_Homo sapiens_hsa049770.14253457
110Notch signaling pathway_Homo sapiens_hsa043300.14219144
111Intestinal immune network for IgA production_Homo sapiens_hsa046720.14015260
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.13957130
113Pathways in cancer_Homo sapiens_hsa052000.13953382
114Hedgehog signaling pathway_Homo sapiens_hsa043400.13466358
115Galactose metabolism_Homo sapiens_hsa000520.12950445
116Chronic myeloid leukemia_Homo sapiens_hsa052200.12788477
117mTOR signaling pathway_Homo sapiens_hsa041500.12519981
118Fatty acid degradation_Homo sapiens_hsa000710.11909338
119Central carbon metabolism in cancer_Homo sapiens_hsa052300.11837911
120Adherens junction_Homo sapiens_hsa045200.09671653
121Peroxisome_Homo sapiens_hsa041460.09404130
122Pancreatic cancer_Homo sapiens_hsa052120.08193604
123Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.08024267
124Pyruvate metabolism_Homo sapiens_hsa006200.07252301
125Tyrosine metabolism_Homo sapiens_hsa003500.06924331
126Hematopoietic cell lineage_Homo sapiens_hsa046400.06627476
127Prostate cancer_Homo sapiens_hsa052150.06611913
128Bladder cancer_Homo sapiens_hsa052190.03064378

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