

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | type B pancreatic cell development (GO:0003323) | 9.58216038 |
| 2 | cerebellar Purkinje cell layer development (GO:0021680) | 6.67934348 |
| 3 | glandular epithelial cell development (GO:0002068) | 6.64114985 |
| 4 | epithelial cell maturation (GO:0002070) | 6.61447756 |
| 5 | regulation of transcription involved in cell fate commitment (GO:0060850) | 5.92661450 |
| 6 | oligodendrocyte differentiation (GO:0048709) | 5.82000988 |
| 7 | synaptic transmission, cholinergic (GO:0007271) | 5.56856278 |
| 8 | response to histamine (GO:0034776) | 5.25752555 |
| 9 | neurofilament cytoskeleton organization (GO:0060052) | 5.25315918 |
| 10 | columnar/cuboidal epithelial cell development (GO:0002066) | 5.21093088 |
| 11 | negative regulation of glial cell differentiation (GO:0045686) | 4.94459847 |
| 12 | pancreas development (GO:0031016) | 4.94033179 |
| 13 | positive regulation of vesicle fusion (GO:0031340) | 4.89798157 |
| 14 | phosphorelay signal transduction system (GO:0000160) | 4.80234214 |
| 15 | endoderm formation (GO:0001706) | 4.80105898 |
| 16 | short-term memory (GO:0007614) | 4.72477797 |
| 17 | inner ear receptor cell development (GO:0060119) | 4.70281062 |
| 18 | L-serine metabolic process (GO:0006563) | 4.69681077 |
| 19 | toxin metabolic process (GO:0009404) | 4.68117424 |
| 20 | positive regulation of glial cell differentiation (GO:0045687) | 4.60805934 |
| 21 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.59971213 |
| 22 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.59971213 |
| 23 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.59971213 |
| 24 | ganglion development (GO:0061548) | 4.44480230 |
| 25 | positive regulation of neurological system process (GO:0031646) | 4.42855341 |
| 26 | epithelial cell differentiation involved in kidney development (GO:0035850) | 4.38715652 |
| 27 | regulation of gene silencing by miRNA (GO:0060964) | 4.33755021 |
| 28 | regulation of gene silencing by RNA (GO:0060966) | 4.33755021 |
| 29 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.33755021 |
| 30 | nephron tubule morphogenesis (GO:0072078) | 4.29210044 |
| 31 | nephron epithelium morphogenesis (GO:0072088) | 4.29210044 |
| 32 | regulation of neuron migration (GO:2001222) | 4.28583802 |
| 33 | spinal cord motor neuron differentiation (GO:0021522) | 4.27386476 |
| 34 | negative regulation of gliogenesis (GO:0014014) | 4.24423405 |
| 35 | inner ear receptor stereocilium organization (GO:0060122) | 4.11077777 |
| 36 | spinal cord association neuron differentiation (GO:0021527) | 3.93200980 |
| 37 | forebrain neuron differentiation (GO:0021879) | 3.91967340 |
| 38 | protein localization to cilium (GO:0061512) | 3.89592487 |
| 39 | nonmotile primary cilium assembly (GO:0035058) | 3.81874456 |
| 40 | head development (GO:0060322) | 3.79731696 |
| 41 | mitochondrial calcium ion transport (GO:0006851) | 3.78025018 |
| 42 | dorsal/ventral neural tube patterning (GO:0021904) | 3.73790080 |
| 43 | endocrine pancreas development (GO:0031018) | 3.65388356 |
| 44 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.63134989 |
| 45 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.62213881 |
| 46 | regulation of ARF protein signal transduction (GO:0032012) | 3.56258442 |
| 47 | dendrite development (GO:0016358) | 3.56015584 |
| 48 | positive regulation of gliogenesis (GO:0014015) | 3.55285824 |
| 49 | intestinal epithelial cell development (GO:0060576) | 3.55228847 |
| 50 | cellular response to ammonium ion (GO:0071242) | 3.49747270 |
| 51 | regulation of cell fate specification (GO:0042659) | 3.46998845 |
| 52 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.39247860 |
| 53 | cerebral cortex neuron differentiation (GO:0021895) | 3.38906741 |
| 54 | heart valve formation (GO:0003188) | 3.33023053 |
| 55 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.32328961 |
| 56 | positive regulation of prostaglandin secretion (GO:0032308) | 3.32022212 |
| 57 | transmission of nerve impulse (GO:0019226) | 3.31827113 |
| 58 | positive regulation of synapse maturation (GO:0090129) | 3.31243540 |
| 59 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.29193135 |
| 60 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.29193135 |
| 61 | positive regulation of muscle cell apoptotic process (GO:0010661) | 3.28761816 |
| 62 | ATP synthesis coupled proton transport (GO:0015986) | 3.27304528 |
| 63 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.27304528 |
| 64 | response to nicotine (GO:0035094) | 3.26752137 |
| 65 | cardiac septum development (GO:0003279) | 3.24913878 |
| 66 | regulation of prostaglandin secretion (GO:0032306) | 3.21546579 |
| 67 | renal tubule morphogenesis (GO:0061333) | 3.19700666 |
| 68 | cornea development in camera-type eye (GO:0061303) | 3.14305448 |
| 69 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.12679065 |
| 70 | positive regulation of antigen processing and presentation (GO:0002579) | 3.04697440 |
| 71 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.03424527 |
| 72 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.03424527 |
| 73 | vesicle transport along microtubule (GO:0047496) | 2.99549152 |
| 74 | ventricular septum development (GO:0003281) | 2.98282404 |
| 75 | activation of protein kinase A activity (GO:0034199) | 2.97527183 |
| 76 | smoothened signaling pathway (GO:0007224) | 2.95218381 |
| 77 | myoblast fusion (GO:0007520) | 2.91480196 |
| 78 | vocalization behavior (GO:0071625) | 2.89250012 |
| 79 | histone H3-K4 trimethylation (GO:0080182) | 2.89166065 |
| 80 | positive regulation of amino acid transport (GO:0051957) | 2.85660649 |
| 81 | intermediate filament organization (GO:0045109) | 2.85202790 |
| 82 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 2.82241347 |
| 83 | viral protein processing (GO:0019082) | 2.82034283 |
| 84 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.80715441 |
| 85 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.80138041 |
| 86 | positive regulation of protein depolymerization (GO:1901881) | 2.79844348 |
| 87 | protein insertion into membrane (GO:0051205) | 2.77450963 |
| 88 | phosphatidylinositol 3-kinase signaling (GO:0014065) | 2.76973976 |
| 89 | axon development (GO:0061564) | 2.75536101 |
| 90 | negative regulation of osteoblast proliferation (GO:0033689) | 2.75536054 |
| 91 | opioid receptor signaling pathway (GO:0038003) | 2.73078931 |
| 92 | behavioral response to nicotine (GO:0035095) | 2.72718917 |
| 93 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 2.67207946 |
| 94 | regulation of synapse maturation (GO:0090128) | 2.66946687 |
| 95 | lateral sprouting from an epithelium (GO:0060601) | 2.64622617 |
| 96 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.63561013 |
| 97 | regulation of glial cell differentiation (GO:0045685) | 2.61848042 |
| 98 | neuromuscular synaptic transmission (GO:0007274) | 2.61507229 |
| 99 | neuronal action potential propagation (GO:0019227) | 2.60822317 |
| 100 | cell differentiation in spinal cord (GO:0021515) | 2.60077575 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.98900142 |
| 2 | TAF15_26573619_Chip-Seq_HEK293_Human | 4.95945828 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.74193949 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.61059592 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.58922351 |
| 6 | RNF2_27304074_Chip-Seq_NSC_Mouse | 3.27270743 |
| 7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.88020108 |
| 8 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.67182200 |
| 9 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.60151764 |
| 10 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.45422655 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.38208746 |
| 12 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.35656440 |
| 13 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.20447529 |
| 14 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.20036208 |
| 15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.15416081 |
| 16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.15250530 |
| 17 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.11627611 |
| 18 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.00671751 |
| 19 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.95140682 |
| 20 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.88695203 |
| 21 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.84919591 |
| 22 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.83034124 |
| 23 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.81551830 |
| 24 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.80454648 |
| 25 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.80131327 |
| 26 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.74122092 |
| 27 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.72309772 |
| 28 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.70591221 |
| 29 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.69158724 |
| 30 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.68874646 |
| 31 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.66558473 |
| 32 | P300_19829295_ChIP-Seq_ESCs_Human | 1.65200822 |
| 33 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.61517886 |
| 34 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.60784336 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.60420728 |
| 36 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.60092252 |
| 37 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.59624492 |
| 38 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.59394439 |
| 39 | EWS_26573619_Chip-Seq_HEK293_Human | 1.56039653 |
| 40 | KDM2B_26808549_Chip-Seq_REH_Human | 1.54100411 |
| 41 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.53433068 |
| 42 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.49555244 |
| 43 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.49517874 |
| 44 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.47013531 |
| 45 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.46084423 |
| 46 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.43667121 |
| 47 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.43258312 |
| 48 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.43258312 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.41708218 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.41298483 |
| 51 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.37877236 |
| 52 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.37468063 |
| 53 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.35582450 |
| 54 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.30800895 |
| 55 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.30638537 |
| 56 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.30427603 |
| 57 | VDR_22108803_ChIP-Seq_LS180_Human | 1.30416823 |
| 58 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.30161677 |
| 59 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.29838643 |
| 60 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.28683570 |
| 61 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.27852858 |
| 62 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.27632492 |
| 63 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.26915359 |
| 64 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.26161280 |
| 65 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24207844 |
| 66 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.22921448 |
| 67 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.22789882 |
| 68 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.22079508 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.20992768 |
| 70 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.19692509 |
| 71 | AR_25329375_ChIP-Seq_VCAP_Human | 1.17564866 |
| 72 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.16198839 |
| 73 | STAT3_23295773_ChIP-Seq_U87_Human | 1.15872471 |
| 74 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.14859503 |
| 75 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.13413045 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.12635714 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.12635714 |
| 78 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.12433747 |
| 79 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.10569821 |
| 80 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.08362138 |
| 81 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.08228192 |
| 82 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.07206670 |
| 83 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.07206670 |
| 84 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03662953 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.02956248 |
| 86 | RXR_22108803_ChIP-Seq_LS180_Human | 1.01618153 |
| 87 | STAT3_18555785_ChIP-Seq_MESCs_Mouse | 0.99822031 |
| 88 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.99248965 |
| 89 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.99167691 |
| 90 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.97846819 |
| 91 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.97023769 |
| 92 | NFYA_21822215_ChIP-Seq_K562_Human | 0.95715799 |
| 93 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94888919 |
| 94 | TBL1_22424771_ChIP-Seq_293T_Human | 0.94061217 |
| 95 | AR_19668381_ChIP-Seq_PC3_Human | 0.93292776 |
| 96 | TCF4_23295773_ChIP-Seq_U87_Human | 0.93050728 |
| 97 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.92305410 |
| 98 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.91889838 |
| 99 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.89772794 |
| 100 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.89483035 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005248_abnormal_Harderian_gland | 5.09669187 |
| 2 | MP0008875_abnormal_xenobiotic_pharmacok | 3.86837656 |
| 3 | MP0001346_abnormal_lacrimal_gland | 3.59762832 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 3.59592714 |
| 5 | MP0004133_heterotaxia | 3.35009900 |
| 6 | MP0003879_abnormal_hair_cell | 2.84721697 |
| 7 | MP0004885_abnormal_endolymph | 2.80702195 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.79357287 |
| 9 | MP0001188_hyperpigmentation | 2.68723864 |
| 10 | MP0004145_abnormal_muscle_electrophysio | 2.63452745 |
| 11 | MP0008877_abnormal_DNA_methylation | 2.50917117 |
| 12 | MP0003787_abnormal_imprinting | 2.47005660 |
| 13 | MP0002735_abnormal_chemical_nociception | 2.38529193 |
| 14 | MP0000955_abnormal_spinal_cord | 2.32988513 |
| 15 | MP0004147_increased_porphyrin_level | 2.29086479 |
| 16 | MP0001486_abnormal_startle_reflex | 2.21146845 |
| 17 | MP0003890_abnormal_embryonic-extraembry | 2.15144802 |
| 18 | MP0009046_muscle_twitch | 2.10539810 |
| 19 | MP0000778_abnormal_nervous_system | 2.05122953 |
| 20 | MP0002009_preneoplasia | 1.93639230 |
| 21 | MP0004043_abnormal_pH_regulation | 1.85514682 |
| 22 | MP0001299_abnormal_eye_distance/ | 1.85338691 |
| 23 | MP0005253_abnormal_eye_physiology | 1.83147734 |
| 24 | MP0000631_abnormal_neuroendocrine_gland | 1.82982573 |
| 25 | MP0001984_abnormal_olfaction | 1.82290089 |
| 26 | MP0000026_abnormal_inner_ear | 1.81124695 |
| 27 | MP0002184_abnormal_innervation | 1.75905758 |
| 28 | MP0002272_abnormal_nervous_system | 1.75797217 |
| 29 | MP0003938_abnormal_ear_development | 1.72107161 |
| 30 | MP0009379_abnormal_foot_pigmentation | 1.61062458 |
| 31 | MP0002736_abnormal_nociception_after | 1.60803733 |
| 32 | MP0009745_abnormal_behavioral_response | 1.57679039 |
| 33 | MP0003941_abnormal_skin_development | 1.47354008 |
| 34 | MP0002752_abnormal_somatic_nervous | 1.47098961 |
| 35 | MP0005423_abnormal_somatic_nervous | 1.45904596 |
| 36 | MP0000647_abnormal_sebaceous_gland | 1.45449942 |
| 37 | MP0003755_abnormal_palate_morphology | 1.42116890 |
| 38 | MP0001286_abnormal_eye_development | 1.38928910 |
| 39 | MP0004782_abnormal_surfactant_physiolog | 1.34990299 |
| 40 | MP0005551_abnormal_eye_electrophysiolog | 1.33950445 |
| 41 | MP0003635_abnormal_synaptic_transmissio | 1.30522051 |
| 42 | MP0001963_abnormal_hearing_physiology | 1.30260625 |
| 43 | MP0009250_abnormal_appendicular_skeleto | 1.29976572 |
| 44 | MP0003567_abnormal_fetal_cardiomyocyte | 1.29746367 |
| 45 | MP0003385_abnormal_body_wall | 1.29117272 |
| 46 | MP0004215_abnormal_myocardial_fiber | 1.27648736 |
| 47 | MP0005394_taste/olfaction_phenotype | 1.26820299 |
| 48 | MP0005499_abnormal_olfactory_system | 1.26820299 |
| 49 | MP0003718_maternal_effect | 1.21960616 |
| 50 | MP0002138_abnormal_hepatobiliary_system | 1.21681823 |
| 51 | MP0005195_abnormal_posterior_eye | 1.19436617 |
| 52 | MP0006292_abnormal_olfactory_placode | 1.16861356 |
| 53 | MP0003121_genomic_imprinting | 1.15404462 |
| 54 | MP0002882_abnormal_neuron_morphology | 1.15041644 |
| 55 | MP0002557_abnormal_social/conspecific_i | 1.14275097 |
| 56 | MP0004742_abnormal_vestibular_system | 1.14169720 |
| 57 | MP0002234_abnormal_pharynx_morphology | 1.13443553 |
| 58 | MP0002697_abnormal_eye_size | 1.10235817 |
| 59 | MP0001968_abnormal_touch/_nociception | 1.08310302 |
| 60 | MP0002572_abnormal_emotion/affect_behav | 1.07867273 |
| 61 | MP0003937_abnormal_limbs/digits/tail_de | 1.06841222 |
| 62 | MP0005083_abnormal_biliary_tract | 1.05546237 |
| 63 | MP0002909_abnormal_adrenal_gland | 1.05143698 |
| 64 | MP0003935_abnormal_craniofacial_develop | 1.04968823 |
| 65 | MP0000049_abnormal_middle_ear | 1.03966725 |
| 66 | MP0001440_abnormal_grooming_behavior | 1.01777728 |
| 67 | MP0005386_behavior/neurological_phenoty | 0.99857475 |
| 68 | MP0004924_abnormal_behavior | 0.99857475 |
| 69 | MP0002932_abnormal_joint_morphology | 0.97945881 |
| 70 | MP0003329_amyloid_beta_deposits | 0.97179487 |
| 71 | MP0002132_abnormal_respiratory_system | 0.97034613 |
| 72 | MP0002277_abnormal_respiratory_mucosa | 0.95895044 |
| 73 | MP0001324_abnormal_eye_pigmentation | 0.95727255 |
| 74 | MP0002067_abnormal_sensory_capabilities | 0.94575306 |
| 75 | MP0004142_abnormal_muscle_tone | 0.93545105 |
| 76 | MP0002734_abnormal_mechanical_nocicepti | 0.93278469 |
| 77 | MP0003119_abnormal_digestive_system | 0.92723904 |
| 78 | MP0003880_abnormal_central_pattern | 0.91710313 |
| 79 | MP0008995_early_reproductive_senescence | 0.91637774 |
| 80 | MP0003122_maternal_imprinting | 0.90605460 |
| 81 | MP0002102_abnormal_ear_morphology | 0.89512533 |
| 82 | MP0001501_abnormal_sleep_pattern | 0.89179939 |
| 83 | MP0000372_irregular_coat_pigmentation | 0.88623352 |
| 84 | MP0005084_abnormal_gallbladder_morpholo | 0.88450412 |
| 85 | MP0003115_abnormal_respiratory_system | 0.87735197 |
| 86 | MP0001986_abnormal_taste_sensitivity | 0.85939320 |
| 87 | MP0002152_abnormal_brain_morphology | 0.84658099 |
| 88 | MP0000613_abnormal_salivary_gland | 0.84504394 |
| 89 | MP0002233_abnormal_nose_morphology | 0.84497667 |
| 90 | MP0004084_abnormal_cardiac_muscle | 0.84048730 |
| 91 | MP0001485_abnormal_pinna_reflex | 0.84027143 |
| 92 | MP0002064_seizures | 0.83334979 |
| 93 | MP0004130_abnormal_muscle_cell | 0.82593748 |
| 94 | MP0003861_abnormal_nervous_system | 0.82089734 |
| 95 | MP0001340_abnormal_eyelid_morphology | 0.79790819 |
| 96 | MP0002751_abnormal_autonomic_nervous | 0.78981905 |
| 97 | MP0002693_abnormal_pancreas_physiology | 0.77694136 |
| 98 | MP0001944_abnormal_pancreas_morphology | 0.77268096 |
| 99 | MP0008789_abnormal_olfactory_epithelium | 0.76686091 |
| 100 | MP0002063_abnormal_learning/memory/cond | 0.75702302 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 6.72363156 |
| 2 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 6.72363156 |
| 3 | Abnormality of the corticospinal tract (HP:0002492) | 5.21029351 |
| 4 | Papilledema (HP:0001085) | 4.98006601 |
| 5 | Urinary urgency (HP:0000012) | 4.58946934 |
| 6 | Insidious onset (HP:0003587) | 4.49481605 |
| 7 | Termporal pattern (HP:0011008) | 4.49481605 |
| 8 | Septo-optic dysplasia (HP:0100842) | 4.42202983 |
| 9 | Overlapping toe (HP:0001845) | 4.01828327 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.93793723 |
| 11 | Calcaneovalgus deformity (HP:0001848) | 3.59182726 |
| 12 | Absent septum pellucidum (HP:0001331) | 3.58281571 |
| 13 | Adrenal hypoplasia (HP:0000835) | 3.57613039 |
| 14 | Hemiparesis (HP:0001269) | 3.53454867 |
| 15 | Medial flaring of the eyebrow (HP:0010747) | 3.40817048 |
| 16 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.35484846 |
| 17 | Deformed tarsal bones (HP:0008119) | 3.33642058 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.28354117 |
| 19 | Gait imbalance (HP:0002141) | 3.21639603 |
| 20 | Colon cancer (HP:0003003) | 3.19028762 |
| 21 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.06660617 |
| 22 | Diastasis recti (HP:0001540) | 3.04395391 |
| 23 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.03676901 |
| 24 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.03143839 |
| 25 | Congenital primary aphakia (HP:0007707) | 3.02425846 |
| 26 | Ulnar claw (HP:0001178) | 2.85049426 |
| 27 | Atonic seizures (HP:0010819) | 2.83538506 |
| 28 | Acute encephalopathy (HP:0006846) | 2.83536795 |
| 29 | Nephrogenic diabetes insipidus (HP:0009806) | 2.83376488 |
| 30 | Abnormality of the septum pellucidum (HP:0007375) | 2.83170260 |
| 31 | Breast hypoplasia (HP:0003187) | 2.78364117 |
| 32 | Lower limb muscle weakness (HP:0007340) | 2.76740465 |
| 33 | Paraplegia (HP:0010550) | 2.68770367 |
| 34 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.60932459 |
| 35 | Cortical dysplasia (HP:0002539) | 2.45977026 |
| 36 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.41881379 |
| 37 | Supernumerary spleens (HP:0009799) | 2.38238094 |
| 38 | Ankle clonus (HP:0011448) | 2.36364299 |
| 39 | Coarctation of aorta (HP:0001680) | 2.35711475 |
| 40 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.32823810 |
| 41 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.32823810 |
| 42 | Single umbilical artery (HP:0001195) | 2.32823810 |
| 43 | Hypoplastic left heart (HP:0004383) | 2.31189868 |
| 44 | True hermaphroditism (HP:0010459) | 2.30992162 |
| 45 | Absent/shortened dynein arms (HP:0200106) | 2.27731333 |
| 46 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.27731333 |
| 47 | Spastic paraplegia (HP:0001258) | 2.27450898 |
| 48 | Proximal amyotrophy (HP:0007126) | 2.24876719 |
| 49 | Poor coordination (HP:0002370) | 2.23637581 |
| 50 | Spinal muscular atrophy (HP:0007269) | 2.23524207 |
| 51 | Nephronophthisis (HP:0000090) | 2.22664669 |
| 52 | Abnormality of midbrain morphology (HP:0002418) | 2.18516137 |
| 53 | Molar tooth sign on MRI (HP:0002419) | 2.18516137 |
| 54 | Abnormality of the calcaneus (HP:0008364) | 2.17663089 |
| 55 | 3-Methylglutaconic aciduria (HP:0003535) | 2.17435652 |
| 56 | Shawl scrotum (HP:0000049) | 2.17183376 |
| 57 | Broad foot (HP:0001769) | 2.16348631 |
| 58 | Focal seizures (HP:0007359) | 2.14986172 |
| 59 | Febrile seizures (HP:0002373) | 2.14806507 |
| 60 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.10376133 |
| 61 | Vaginal atresia (HP:0000148) | 2.08158338 |
| 62 | Hypoplastic iliac wings (HP:0002866) | 2.07838865 |
| 63 | Spastic gait (HP:0002064) | 2.07306298 |
| 64 | Mitochondrial inheritance (HP:0001427) | 2.06332483 |
| 65 | Cerebral edema (HP:0002181) | 2.04981890 |
| 66 | Optic nerve hypoplasia (HP:0000609) | 2.02669426 |
| 67 | Growth hormone deficiency (HP:0000824) | 1.99384881 |
| 68 | Coronal craniosynostosis (HP:0004440) | 1.98169677 |
| 69 | Chin dimple (HP:0010751) | 1.97522374 |
| 70 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.94474234 |
| 71 | Genital tract atresia (HP:0001827) | 1.94276834 |
| 72 | Pancreatic fibrosis (HP:0100732) | 1.91604769 |
| 73 | Congenital, generalized hypertrichosis (HP:0004540) | 1.90412261 |
| 74 | Hypoplastic heart (HP:0001961) | 1.89974369 |
| 75 | Chronic bronchitis (HP:0004469) | 1.89659707 |
| 76 | Frequent falls (HP:0002359) | 1.86392927 |
| 77 | Genetic anticipation (HP:0003743) | 1.86088957 |
| 78 | Pterygium (HP:0001059) | 1.85145160 |
| 79 | Abnormality of the umbilical cord (HP:0010881) | 1.82481349 |
| 80 | Focal motor seizures (HP:0011153) | 1.81677318 |
| 81 | Woolly hair (HP:0002224) | 1.80963638 |
| 82 | Abnormality of homocysteine metabolism (HP:0010919) | 1.79275271 |
| 83 | Homocystinuria (HP:0002156) | 1.79275271 |
| 84 | Abnormality of the vocal cords (HP:0008777) | 1.79237488 |
| 85 | Abnormality of the fingertips (HP:0001211) | 1.78729733 |
| 86 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.78154881 |
| 87 | Abnormality of the renal medulla (HP:0100957) | 1.74930681 |
| 88 | Pachygyria (HP:0001302) | 1.72931524 |
| 89 | Hemiplegia (HP:0002301) | 1.70855849 |
| 90 | Biliary tract neoplasm (HP:0100574) | 1.70285802 |
| 91 | Exotropia (HP:0000577) | 1.70272876 |
| 92 | Absence seizures (HP:0002121) | 1.68522725 |
| 93 | Down-sloping shoulders (HP:0200021) | 1.68263217 |
| 94 | Asymmetric growth (HP:0100555) | 1.67608335 |
| 95 | Volvulus (HP:0002580) | 1.67475586 |
| 96 | Occipital encephalocele (HP:0002085) | 1.66918650 |
| 97 | Increased CSF lactate (HP:0002490) | 1.65645036 |
| 98 | Hypoplastic labia majora (HP:0000059) | 1.64828386 |
| 99 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.64801849 |
| 100 | Neoplasm of head and neck (HP:0012288) | 1.63697001 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK1 | 9.31008645 |
| 2 | NME1 | 4.72420952 |
| 3 | DYRK1B | 3.93238572 |
| 4 | IRAK3 | 3.60017023 |
| 5 | WNK3 | 3.52673849 |
| 6 | PINK1 | 2.78480056 |
| 7 | EPHB2 | 2.60040031 |
| 8 | ICK | 2.54424721 |
| 9 | MAP3K4 | 2.38403722 |
| 10 | TNIK | 2.16626344 |
| 11 | ADRBK2 | 1.98554602 |
| 12 | STK11 | 1.85116275 |
| 13 | TAF1 | 1.81821418 |
| 14 | MARK1 | 1.81270917 |
| 15 | FRK | 1.74999490 |
| 16 | LATS2 | 1.67682535 |
| 17 | UHMK1 | 1.53991313 |
| 18 | TYRO3 | 1.41088530 |
| 19 | LIMK1 | 1.40546673 |
| 20 | MARK2 | 1.32233394 |
| 21 | MAP2K2 | 1.30513366 |
| 22 | MKNK2 | 1.30043270 |
| 23 | NTRK2 | 1.29799782 |
| 24 | NLK | 1.26222674 |
| 25 | NEK2 | 1.12335899 |
| 26 | CDK3 | 1.08970074 |
| 27 | MINK1 | 1.07980034 |
| 28 | MAP4K2 | 1.05596116 |
| 29 | YES1 | 1.04935755 |
| 30 | PHKG1 | 1.02459885 |
| 31 | PHKG2 | 1.02459885 |
| 32 | CDK19 | 1.00783677 |
| 33 | DYRK2 | 0.98913697 |
| 34 | MKNK1 | 0.96765324 |
| 35 | CAMK2A | 0.88681030 |
| 36 | NTRK1 | 0.88416901 |
| 37 | VRK2 | 0.84207991 |
| 38 | BCR | 0.83120288 |
| 39 | SGK1 | 0.80386227 |
| 40 | SGK2 | 0.77586922 |
| 41 | CDK8 | 0.71394392 |
| 42 | EIF2AK3 | 0.70146808 |
| 43 | MAPK12 | 0.69396244 |
| 44 | MAP3K6 | 0.69139543 |
| 45 | CDK9 | 0.66815912 |
| 46 | PRKG1 | 0.65345422 |
| 47 | WNK1 | 0.64537792 |
| 48 | TIE1 | 0.59421267 |
| 49 | OXSR1 | 0.58581817 |
| 50 | RPS6KA4 | 0.56067177 |
| 51 | CSNK1E | 0.51662135 |
| 52 | CDK6 | 0.51203091 |
| 53 | SIK2 | 0.48100247 |
| 54 | EIF2AK1 | 0.48020857 |
| 55 | DYRK3 | 0.46587782 |
| 56 | SGK223 | 0.45456665 |
| 57 | SGK494 | 0.45456665 |
| 58 | NEK6 | 0.44478986 |
| 59 | TAOK3 | 0.43666445 |
| 60 | WNK4 | 0.43207654 |
| 61 | NUAK1 | 0.40477992 |
| 62 | PRKCG | 0.39868491 |
| 63 | MAPK13 | 0.36723300 |
| 64 | RPS6KL1 | 0.36079574 |
| 65 | RPS6KC1 | 0.36079574 |
| 66 | CAMK1 | 0.35989053 |
| 67 | RPS6KA6 | 0.35637381 |
| 68 | DDR2 | 0.34877263 |
| 69 | VRK1 | 0.34034997 |
| 70 | CDK5 | 0.33947333 |
| 71 | MAPK4 | 0.33672277 |
| 72 | DYRK1A | 0.32338957 |
| 73 | MAPK9 | 0.31805809 |
| 74 | PDGFRA | 0.31284547 |
| 75 | MAP3K7 | 0.31242360 |
| 76 | CDK7 | 0.30869086 |
| 77 | ITK | 0.30036308 |
| 78 | TESK1 | 0.29872901 |
| 79 | MELK | 0.27344162 |
| 80 | SGK3 | 0.26690343 |
| 81 | BMPR1B | 0.26502740 |
| 82 | RPS6KA3 | 0.26424779 |
| 83 | TRIM28 | 0.25861063 |
| 84 | CDK14 | 0.24853461 |
| 85 | TSSK6 | 0.24391561 |
| 86 | SIK3 | 0.23791655 |
| 87 | OBSCN | 0.23762340 |
| 88 | CSNK1A1 | 0.23455507 |
| 89 | PRKACA | 0.23422969 |
| 90 | CHUK | 0.23061036 |
| 91 | PIM1 | 0.22796551 |
| 92 | MAP2K7 | 0.21001688 |
| 93 | TGFBR1 | 0.20859424 |
| 94 | FYN | 0.18987946 |
| 95 | CAMKK2 | 0.18549714 |
| 96 | INSRR | 0.17444543 |
| 97 | AURKB | 0.17248521 |
| 98 | PRKD1 | 0.17038470 |
| 99 | PRKAA1 | 0.16616072 |
| 100 | CAMK2D | 0.15308649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 6.34550862 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.34481113 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.25605600 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.97926828 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.95118740 |
| 6 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.81174036 |
| 7 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.66688487 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.60282551 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.42422826 |
| 10 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 2.29972373 |
| 11 | GABAergic synapse_Homo sapiens_hsa04727 | 2.16956792 |
| 12 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.90469915 |
| 13 | Morphine addiction_Homo sapiens_hsa05032 | 1.88104664 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.78402006 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.75486815 |
| 16 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.71179841 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.68008321 |
| 18 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.67803383 |
| 19 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.63269220 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.59025598 |
| 21 | Ribosome_Homo sapiens_hsa03010 | 1.51504805 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.46891436 |
| 23 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.43929517 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.33596420 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.24562698 |
| 26 | Taste transduction_Homo sapiens_hsa04742 | 1.22057591 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.13685300 |
| 28 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.12773204 |
| 29 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.11631591 |
| 30 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.05285870 |
| 31 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.04165971 |
| 32 | Phagosome_Homo sapiens_hsa04145 | 1.03873534 |
| 33 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.03298049 |
| 34 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.02319038 |
| 35 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.01398668 |
| 36 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.98871216 |
| 37 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.96314782 |
| 38 | Axon guidance_Homo sapiens_hsa04360 | 0.91981608 |
| 39 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.88151205 |
| 40 | Insulin secretion_Homo sapiens_hsa04911 | 0.86883259 |
| 41 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.81176663 |
| 42 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.77057792 |
| 43 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.76774836 |
| 44 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.75576215 |
| 45 | Circadian entrainment_Homo sapiens_hsa04713 | 0.74007367 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.73457565 |
| 47 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72531099 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.71072947 |
| 49 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.70849351 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.66794489 |
| 51 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.65952152 |
| 52 | RNA polymerase_Homo sapiens_hsa03020 | 0.65439738 |
| 53 | Salivary secretion_Homo sapiens_hsa04970 | 0.65418658 |
| 54 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.65206831 |
| 55 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.63314142 |
| 56 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.61802591 |
| 57 | RNA transport_Homo sapiens_hsa03013 | 0.55657457 |
| 58 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.54991151 |
| 59 | Bile secretion_Homo sapiens_hsa04976 | 0.54438999 |
| 60 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.53867241 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50568819 |
| 62 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.49762548 |
| 63 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.49240582 |
| 64 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.48506782 |
| 65 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.47145287 |
| 66 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.46575226 |
| 67 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.45211301 |
| 68 | Gap junction_Homo sapiens_hsa04540 | 0.45029637 |
| 69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.44956904 |
| 70 | Peroxisome_Homo sapiens_hsa04146 | 0.44453194 |
| 71 | Homologous recombination_Homo sapiens_hsa03440 | 0.43661933 |
| 72 | Melanogenesis_Homo sapiens_hsa04916 | 0.43462981 |
| 73 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.43337002 |
| 74 | Tight junction_Homo sapiens_hsa04530 | 0.40964557 |
| 75 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.39478393 |
| 76 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.38606773 |
| 77 | Cell cycle_Homo sapiens_hsa04110 | 0.36185919 |
| 78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.33916333 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33544353 |
| 80 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.31733066 |
| 81 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.31686423 |
| 82 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.31621895 |
| 83 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.30295489 |
| 84 | Melanoma_Homo sapiens_hsa05218 | 0.29904316 |
| 85 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.28171395 |
| 86 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.27840363 |
| 87 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.26669042 |
| 88 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.26309973 |
| 89 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.25845478 |
| 90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25330580 |
| 91 | Asthma_Homo sapiens_hsa05310 | 0.24753613 |
| 92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.24472816 |
| 93 | Salmonella infection_Homo sapiens_hsa05132 | 0.24341246 |
| 94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.24166506 |
| 95 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.23825637 |
| 96 | Mineral absorption_Homo sapiens_hsa04978 | 0.23735506 |
| 97 | Renin secretion_Homo sapiens_hsa04924 | 0.22099017 |
| 98 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.21706889 |
| 99 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.20921559 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.20854380 |

