KRR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.67195125
2DNA replication checkpoint (GO:0000076)4.65349515
3protein localization to kinetochore (GO:0034501)4.60665022
4kinetochore organization (GO:0051383)4.33511835
5DNA replication initiation (GO:0006270)4.30132338
6nuclear pore organization (GO:0006999)4.25430325
7ribosome assembly (GO:0042255)4.24889883
8regulation of centriole replication (GO:0046599)4.23326464
9nuclear pore complex assembly (GO:0051292)4.21142575
10CENP-A containing nucleosome assembly (GO:0034080)4.17943321
11chromatin remodeling at centromere (GO:0031055)4.15204601
12maturation of SSU-rRNA (GO:0030490)4.13577071
13metaphase plate congression (GO:0051310)4.05561827
14kinetochore assembly (GO:0051382)3.97284429
15protein localization to chromosome, centromeric region (GO:0071459)3.94148328
16DNA unwinding involved in DNA replication (GO:0006268)3.90210497
17DNA strand elongation involved in DNA replication (GO:0006271)3.89869449
18nucleobase biosynthetic process (GO:0046112)3.87309948
19telomere maintenance via semi-conservative replication (GO:0032201)3.85495580
20mitotic nuclear envelope disassembly (GO:0007077)3.83277914
21purine nucleobase biosynthetic process (GO:0009113)3.81150412
22ribosome biogenesis (GO:0042254)3.79034284
23DNA replication-independent nucleosome organization (GO:0034724)3.77822146
24DNA replication-independent nucleosome assembly (GO:0006336)3.77822146
25IMP biosynthetic process (GO:0006188)3.76395731
26double-strand break repair via nonhomologous end joining (GO:0006303)3.75192661
27non-recombinational repair (GO:0000726)3.75192661
28attachment of spindle microtubules to kinetochore (GO:0008608)3.74428161
29telomere maintenance via recombination (GO:0000722)3.70996053
30DNA strand elongation (GO:0022616)3.70691726
31establishment of chromosome localization (GO:0051303)3.69413655
32regulation of spindle organization (GO:0090224)3.67498046
33mitotic recombination (GO:0006312)3.65030384
34formation of translation preinitiation complex (GO:0001731)3.60217429
35regulation of centrosome cycle (GO:0046605)3.55243686
36establishment of integrated proviral latency (GO:0075713)3.53757633
37nuclear envelope disassembly (GO:0051081)3.53590976
38membrane disassembly (GO:0030397)3.53590976
39ncRNA 3-end processing (GO:0043628)3.49272056
40ribosomal small subunit assembly (GO:0000028)3.47806623
41negative regulation of DNA repair (GO:0045738)3.44082554
42histone exchange (GO:0043486)3.43586708
43viral mRNA export from host cell nucleus (GO:0046784)3.42550128
44regulation of double-strand break repair via homologous recombination (GO:0010569)3.41875625
45ribonucleoprotein complex biogenesis (GO:0022613)3.41501545
46regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.40599622
47regulation of mitotic spindle checkpoint (GO:1903504)3.40599622
48IMP metabolic process (GO:0046040)3.39534118
49mitotic sister chromatid cohesion (GO:0007064)3.38626558
50mitotic G2/M transition checkpoint (GO:0044818)3.36411719
51regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.36136427
52pore complex assembly (GO:0046931)3.33520489
53DNA replication-dependent nucleosome organization (GO:0034723)3.32901105
54DNA replication-dependent nucleosome assembly (GO:0006335)3.32901105
55telomere maintenance via telomere lengthening (GO:0010833)3.31914129
56negative regulation of DNA-dependent DNA replication (GO:2000104)3.30255429
57ribosomal large subunit biogenesis (GO:0042273)3.29020811
58positive regulation of chromosome segregation (GO:0051984)3.28988128
59regulation of RNA export from nucleus (GO:0046831)3.26769744
60maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.26455828
61regulation of nuclear cell cycle DNA replication (GO:0033262)3.24264194
62DNA ligation (GO:0006266)3.21137965
63monoubiquitinated protein deubiquitination (GO:0035520)3.21031946
64protein K6-linked ubiquitination (GO:0085020)3.20920002
65spindle checkpoint (GO:0031577)3.20801783
66sister chromatid cohesion (GO:0007062)3.20107054
67DNA geometric change (GO:0032392)3.19701079
68DNA duplex unwinding (GO:0032508)3.18750313
69mitotic chromosome condensation (GO:0007076)3.16797715
70folic acid-containing compound biosynthetic process (GO:0009396)3.16163339
71regulation of mitotic spindle organization (GO:0060236)3.15093795
72RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.14237339
73regulation of centrosome duplication (GO:0010824)3.14207955
74somatic recombination of immunoglobulin gene segments (GO:0016447)3.12862269
75* rRNA processing (GO:0006364)3.12857925
76centriole replication (GO:0007099)3.12211009
77meiotic chromosome segregation (GO:0045132)3.11027621
78somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.09943729
79isotype switching (GO:0045190)3.09943729
80somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.09943729
81regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.09205605
82positive regulation of histone H3-K4 methylation (GO:0051571)3.06706593
83positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.05774413
84positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.05774413
85positive regulation of mitotic sister chromatid separation (GO:1901970)3.05774413
86telomere maintenance (GO:0000723)3.05437663
87spindle assembly checkpoint (GO:0071173)3.04195954
88* rRNA metabolic process (GO:0016072)3.04003986
89regulation of mitotic metaphase/anaphase transition (GO:0030071)3.03894868
90protein localization to chromosome (GO:0034502)3.03402429
91response to X-ray (GO:0010165)3.02946922
92telomere organization (GO:0032200)3.02582619
93mitotic sister chromatid segregation (GO:0000070)3.02416129
94chromatin assembly or disassembly (GO:0006333)3.01922183
95spliceosomal snRNP assembly (GO:0000387)3.01828641
96transcription elongation from RNA polymerase I promoter (GO:0006362)3.01542329
97positive regulation of cell cycle checkpoint (GO:1901978)3.01476270
98replication fork processing (GO:0031297)3.01464685
99mitochondrial RNA metabolic process (GO:0000959)2.98503219
100regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.96994408
101regulation of sister chromatid cohesion (GO:0007063)2.96519304
102histone mRNA metabolic process (GO:0008334)2.95634739
103DNA topological change (GO:0006265)2.93975621
104nucleotide-excision repair, DNA gap filling (GO:0006297)2.90981407
105sister chromatid segregation (GO:0000819)2.90937028
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.90434904
107negative regulation of sister chromatid segregation (GO:0033046)2.90434904
108negative regulation of mitotic sister chromatid separation (GO:2000816)2.90434904
109negative regulation of mitotic sister chromatid segregation (GO:0033048)2.90434904
110mitotic G2 DNA damage checkpoint (GO:0007095)2.90429259
111somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.89737489
112somatic cell DNA recombination (GO:0016444)2.89737489
113translesion synthesis (GO:0019985)2.89725543
114negative regulation of chromosome segregation (GO:0051985)2.89290725
115maturation of 5.8S rRNA (GO:0000460)2.88258466
116mitotic spindle checkpoint (GO:0071174)2.87935841
117regulation of chromosome segregation (GO:0051983)2.87258418
118ATP-dependent chromatin remodeling (GO:0043044)2.86842680
119DNA deamination (GO:0045006)2.86738644
120intra-S DNA damage checkpoint (GO:0031573)2.86340546
121mitotic spindle assembly checkpoint (GO:0007094)2.86321997
122regulation of DNA endoreduplication (GO:0032875)2.84008682
123regulation of mitotic sister chromatid separation (GO:0010965)2.83587879
124regulation of mitotic sister chromatid segregation (GO:0033047)2.83587879
125regulation of sister chromatid segregation (GO:0033045)2.83587879
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.81900778
127rRNA modification (GO:0000154)2.80397320
128regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.77380542
129histone-serine phosphorylation (GO:0035404)2.77278472

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.59786918
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.55428275
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.33330769
4* MYC_18555785_ChIP-Seq_MESCs_Mouse3.95007042
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.24484549
6* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.89742222
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.83073210
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.78412928
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.73585294
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69323973
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.58153703
12* ETS1_20019798_ChIP-Seq_JURKAT_Human2.46897744
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.45760346
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.40773622
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.39858505
16* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.37215266
17* VDR_23849224_ChIP-Seq_CD4+_Human2.35918342
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.33237999
19* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.32008139
20E2F1_21310950_ChIP-Seq_MCF-7_Human2.29705163
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19400170
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.14261362
23* ELK1_19687146_ChIP-ChIP_HELA_Human2.11984311
24* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.09619238
25* FOXP3_21729870_ChIP-Seq_TREG_Human2.03178421
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.02323704
27AR_21909140_ChIP-Seq_LNCAP_Human2.02317756
28EWS_26573619_Chip-Seq_HEK293_Human2.00991928
29* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.98515913
30XRN2_22483619_ChIP-Seq_HELA_Human1.95986319
31MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93813178
32FUS_26573619_Chip-Seq_HEK293_Human1.88751717
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.86716635
34MYCN_18555785_ChIP-Seq_MESCs_Mouse1.84192416
35YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.83423115
36DCP1A_22483619_ChIP-Seq_HELA_Human1.82635416
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81853090
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.81731023
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79823311
40* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.79708129
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74598287
42* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72136880
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.72130829
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68362976
45HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68356842
46* TTF2_22483619_ChIP-Seq_HELA_Human1.65176015
47GABP_19822575_ChIP-Seq_HepG2_Human1.61443568
48HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.60197037
49KDM5A_27292631_Chip-Seq_BREAST_Human1.58449555
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.55808640
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53810136
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.53672529
53* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.52949259
54CIITA_25753668_ChIP-Seq_RAJI_Human1.52211800
55SALL1_21062744_ChIP-ChIP_HESCs_Human1.46449368
56MYC_22102868_ChIP-Seq_BL_Human1.44876273
57SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.42782905
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.40874943
59* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.40515451
60ERG_20887958_ChIP-Seq_HPC-7_Mouse1.39293336
61BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.38424127
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.36386164
63* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.35834741
64* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.32368276
65SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.32140550
66SPI1_23547873_ChIP-Seq_NB4_Human1.32038180
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.29739250
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29692652
69ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.27857860
70CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.27727304
71TFEB_21752829_ChIP-Seq_HELA_Human1.26721256
72YY1_21170310_ChIP-Seq_MESCs_Mouse1.21713480
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.21443065
74IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.16812740
75RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15476458
76E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15357779
77TAF15_26573619_Chip-Seq_HEK293_Human1.14592155
78* SRF_21415370_ChIP-Seq_HL-1_Mouse1.12212803
79IGF1R_20145208_ChIP-Seq_DFB_Human1.11741905
80MYB_21317192_ChIP-Seq_ERMYB_Mouse1.09322027
81RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09308599
82* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.09118757
83VDR_22108803_ChIP-Seq_LS180_Human1.05807192
84ZNF274_21170338_ChIP-Seq_K562_Hela1.04830407
85SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03372251
86GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01425906
87SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.01088571
88MYC_18940864_ChIP-ChIP_HL60_Human1.00492300
89GATA1_22025678_ChIP-Seq_K562_Human0.99350717
90ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99188006
91STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98075936
92IRF8_21731497_ChIP-ChIP_J774_Mouse0.97468851
93FOXM1_26456572_ChIP-Seq_MCF-7_Human0.92129055
94KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92056841
95IRF1_19129219_ChIP-ChIP_H3396_Human0.91563349
96* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.91115656
97POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90246151
98FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.89911052
99MYB_26560356_Chip-Seq_TH2_Human0.89686966
100PCGF2_27294783_Chip-Seq_ESCs_Mouse0.88764353
101HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.88459000
102FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.88155239
103SOX17_20123909_ChIP-Seq_XEN_Mouse0.88130909
104MYB_26560356_Chip-Seq_TH1_Human0.88073188
105FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.87733415
106SCL_19346495_ChIP-Seq_HPC-7_Human0.86745303
107* CHD1_26751641_Chip-Seq_LNCaP_Human0.84808043
108ELK1_22589737_ChIP-Seq_MCF10A_Human0.84691853
109CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.84663777
110GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83718292
111PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.83227506
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.82760769
113ER_23166858_ChIP-Seq_MCF-7_Human0.82670824
114IRF8_22096565_ChIP-ChIP_GC-B_Human0.82324229
115HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.82162342
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.82022374
117EZH2_27294783_Chip-Seq_NPCs_Mouse0.81031832
118FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.80858016
119ELF5_23300383_ChIP-Seq_T47D_Human0.80329099
120SOX2_18555785_ChIP-Seq_MESCs_Mouse0.80106395
121NANOG_16153702_ChIP-ChIP_HESCs_Human0.80077669
122P300_19829295_ChIP-Seq_ESCs_Human0.79913409
123DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.79823289
124CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79740734
125DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.79289389
126KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.79242649
127KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.79242649
128KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.79242649
129SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.78693729
130PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.78236849
131BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.78156085
132KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.76485365
133VDR_21846776_ChIP-Seq_THP-1_Human0.74047014
134CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.72515729

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.03776928
2MP0010094_abnormal_chromosome_stability4.63031668
3MP0008057_abnormal_DNA_replication4.34943251
4MP0003111_abnormal_nucleus_morphology4.18089368
5MP0003077_abnormal_cell_cycle3.86295824
6MP0004957_abnormal_blastocyst_morpholog3.73358965
7MP0002396_abnormal_hematopoietic_system3.48289407
8MP0008058_abnormal_DNA_repair3.34387785
9MP0008007_abnormal_cellular_replicative3.17912389
10MP0003123_paternal_imprinting2.41973003
11MP0000569_abnormal_digit_pigmentation2.26614759
12MP0010307_abnormal_tumor_latency2.26392137
13MP0008932_abnormal_embryonic_tissue2.22680007
14MP0008877_abnormal_DNA_methylation2.12368494
15MP0000350_abnormal_cell_proliferation2.04208446
16MP0004808_abnormal_hematopoietic_stem1.96526585
17MP0001730_embryonic_growth_arrest1.88665950
18MP0003786_premature_aging1.88201756
19MP0005174_abnormal_tail_pigmentation1.84809102
20MP0010352_gastrointestinal_tract_polyps1.69883151
21MP0000490_abnormal_crypts_of1.69073131
22MP0000015_abnormal_ear_pigmentation1.61353158
23MP0005076_abnormal_cell_differentiation1.58112760
24MP0002398_abnormal_bone_marrow1.57729719
25MP0005397_hematopoietic_system_phenotyp1.57482178
26MP0001545_abnormal_hematopoietic_system1.57482178
27MP0003763_abnormal_thymus_physiology1.54649655
28MP0003950_abnormal_plasma_membrane1.53882891
29MP0001835_abnormal_antigen_presentation1.53877195
30MP0003718_maternal_effect1.52387408
31MP0010234_abnormal_vibrissa_follicle1.50027967
32MP0005380_embryogenesis_phenotype1.47323413
33MP0001672_abnormal_embryogenesis/_devel1.47323413
34MP0001697_abnormal_embryo_size1.46611113
35MP0006292_abnormal_olfactory_placode1.45602424
36MP0002019_abnormal_tumor_incidence1.40525823
37MP0000703_abnormal_thymus_morphology1.39966398
38MP0003121_genomic_imprinting1.37414869
39MP0000313_abnormal_cell_death1.35727815
40MP0002160_abnormal_reproductive_system1.34783496
41MP0000689_abnormal_spleen_morphology1.34137771
42MP0002722_abnormal_immune_system1.31086330
43MP0002080_prenatal_lethality1.31068209
44MP0003984_embryonic_growth_retardation1.30971006
45MP0003567_abnormal_fetal_cardiomyocyte1.30957992
46MP0003937_abnormal_limbs/digits/tail_de1.30062439
47MP0001800_abnormal_humoral_immune1.28432739
48MP0002095_abnormal_skin_pigmentation1.28113673
49MP0002088_abnormal_embryonic_growth/wei1.27832030
50MP0010678_abnormal_skin_adnexa1.26454043
51MP0001853_heart_inflammation1.25808592
52MP0002452_abnormal_antigen_presenting1.25628636
53MP0003890_abnormal_embryonic-extraembry1.25227003
54MP0004185_abnormal_adipocyte_glucose1.23952955
55MP0002086_abnormal_extraembryonic_tissu1.23661263
56MP0009333_abnormal_splenocyte_physiolog1.22078974
57MP0002420_abnormal_adaptive_immunity1.18304075
58MP0001819_abnormal_immune_cell1.16974013
59MP0000716_abnormal_immune_system1.15928516
60MP0004197_abnormal_fetal_growth/weight/1.15719934
61MP0002084_abnormal_developmental_patter1.15553011
62MP0000858_altered_metastatic_potential1.13627869
63MP0002429_abnormal_blood_cell1.13560658
64MP0003221_abnormal_cardiomyocyte_apopto1.12549887
65MP0002085_abnormal_embryonic_tissue1.12500256
66MP0002166_altered_tumor_susceptibility1.10340581
67MP0002723_abnormal_immune_serum1.09496621
68MP0002102_abnormal_ear_morphology1.09295877
69MP0002006_tumorigenesis1.07677047
70MP0000427_abnormal_hair_cycle1.07633050
71MP0006072_abnormal_retinal_apoptosis1.06358460
72MP0001286_abnormal_eye_development1.05626221
73MP0001293_anophthalmia1.05519136
74MP0005075_abnormal_melanosome_morpholog1.04468288
75MP0000372_irregular_coat_pigmentation1.04168070
76MP0000383_abnormal_hair_follicle1.03413841
77MP0003303_peritoneal_inflammation1.03152866
78MP0008961_abnormal_basal_metabolism1.02903768
79MP0002210_abnormal_sex_determination0.98650834
80MP0005671_abnormal_response_to0.97230604
81MP0002419_abnormal_innate_immunity0.95344029
82MP0005025_abnormal_response_to0.94747342
83MP0001188_hyperpigmentation0.92797850
84MP0005621_abnormal_cell_physiology0.92154766
85MP0003941_abnormal_skin_development0.90778720
86MP0003448_altered_tumor_morphology0.90275281
87MP0009278_abnormal_bone_marrow0.89939871
88MP0005000_abnormal_immune_tolerance0.88680515
89MP0000371_diluted_coat_color0.88669081
90MP0003943_abnormal_hepatobiliary_system0.88553214
91MP0009703_decreased_birth_body0.87952071
92MP0005187_abnormal_penis_morphology0.87631365
93MP0006036_abnormal_mitochondrial_physio0.87593691
94MP0002234_abnormal_pharynx_morphology0.87398781
95MP0003436_decreased_susceptibility_to0.87090167
96MP0005384_cellular_phenotype0.85169166
97MP0009785_altered_susceptibility_to0.85103391
98MP0002277_abnormal_respiratory_mucosa0.83511831
99MP0002009_preneoplasia0.82440043
100MP0002697_abnormal_eye_size0.82333149
101MP0002233_abnormal_nose_morphology0.81858879
102MP0005389_reproductive_system_phenotype0.81349191
103MP0000428_abnormal_craniofacial_morphol0.81326222
104MP0004147_increased_porphyrin_level0.81027517
105MP0006035_abnormal_mitochondrial_morpho0.79780017
106MP0001145_abnormal_male_reproductive0.79549498
107MP0003787_abnormal_imprinting0.77976042
108MP0009697_abnormal_copulation0.77224592
109MP0002148_abnormal_hypersensitivity_rea0.77089476
110MP0000358_abnormal_cell_content/0.76372894
111MP0002405_respiratory_system_inflammati0.76041119
112MP0003656_abnormal_erythrocyte_physiolo0.75698325
113MP0002075_abnormal_coat/hair_pigmentati0.74032277
114MP0004264_abnormal_extraembryonic_tissu0.71995679
115MP0002163_abnormal_gland_morphology0.71691165
116MP0001929_abnormal_gametogenesis0.71594077
117MP0000685_abnormal_immune_system0.70912895
118MP0005408_hypopigmentation0.70096368
119MP0002877_abnormal_melanocyte_morpholog0.69661554
120MP0003699_abnormal_female_reproductive0.69262240
121MP0001119_abnormal_female_reproductive0.68723470
122MP0002092_abnormal_eye_morphology0.68309129
123MP0005266_abnormal_metabolism0.67753984
124MP0000647_abnormal_sebaceous_gland0.67543891
125MP0009379_abnormal_foot_pigmentation0.67410044
126MP0008995_early_reproductive_senescence0.66995285
127MP0005387_immune_system_phenotype0.66977375
128MP0001790_abnormal_immune_system0.66977375
129MP0004233_abnormal_muscle_weight0.66782596
130MP0005464_abnormal_platelet_physiology0.66598558
131MP0005395_other_phenotype0.66431398
132MP0000465_gastrointestinal_hemorrhage0.66392976
133MP0005220_abnormal_exocrine_pancreas0.65886090
134MP0000653_abnormal_sex_gland0.65426044
135MP0000627_abnormal_mammary_gland0.64554540
136MP0009672_abnormal_birth_weight0.64446346
137MP0001186_pigmentation_phenotype0.64091512
138MP0002177_abnormal_outer_ear0.62778251
139MP0003755_abnormal_palate_morphology0.60620361
140MP0003935_abnormal_craniofacial_develop0.60154612
141MP0002269_muscular_atrophy0.59785768
142MP0003936_abnormal_reproductive_system0.59599784
143MP0004215_abnormal_myocardial_fiber0.58259155
144MP0002111_abnormal_tail_morphology0.57175743
145MP0003698_abnormal_male_reproductive0.56624534
146MP0003646_muscle_fatigue0.55466511

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)6.02136720
2Chromosomal breakage induced by crosslinking agents (HP:0003221)5.68595074
3Birth length less than 3rd percentile (HP:0003561)4.96187125
4Reticulocytopenia (HP:0001896)4.51850514
5Abnormality of chromosome stability (HP:0003220)3.91281287
6Abnormality of the preputium (HP:0100587)3.54285612
7Meckel diverticulum (HP:0002245)3.53066314
8Duplicated collecting system (HP:0000081)3.39539005
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.32949060
10Abnormality of the ileum (HP:0001549)3.31992504
11Impulsivity (HP:0100710)3.18411572
12Ectopic kidney (HP:0000086)3.13116405
13Degeneration of anterior horn cells (HP:0002398)3.10267931
14Abnormality of the anterior horn cell (HP:0006802)3.10267931
15Myelodysplasia (HP:0002863)3.09848224
16Clubbing of toes (HP:0100760)3.07104151
17Abnormality of the renal collecting system (HP:0004742)3.05481127
18Abnormality of DNA repair (HP:0003254)3.04331295
19Bone marrow hypocellularity (HP:0005528)3.03450744
20Agnosia (HP:0010524)3.01537389
21Breast hypoplasia (HP:0003187)3.00153114
22Absent thumb (HP:0009777)2.99371408
23Embryonal renal neoplasm (HP:0011794)2.98857093
24Volvulus (HP:0002580)2.98762842
25Rough bone trabeculation (HP:0100670)2.89952736
26Premature graying of hair (HP:0002216)2.84586328
27Colon cancer (HP:0003003)2.82511956
28Patellar aplasia (HP:0006443)2.72067969
29Duodenal stenosis (HP:0100867)2.71904768
30Small intestinal stenosis (HP:0012848)2.71904768
31Oral leukoplakia (HP:0002745)2.69135075
32Sloping forehead (HP:0000340)2.65545961
33Abnormal number of erythroid precursors (HP:0012131)2.54770514
34Pallor (HP:0000980)2.54039805
35Aplastic anemia (HP:0001915)2.53295651
36Abnormality of cells of the erythroid lineage (HP:0012130)2.52771710
37Absent radius (HP:0003974)2.52203743
38Papillary thyroid carcinoma (HP:0002895)2.51542707
39Aplasia/Hypoplasia of the patella (HP:0006498)2.48269591
40Abnormal lung lobation (HP:0002101)2.45871497
41Acute myeloid leukemia (HP:0004808)2.42933279
42Medulloblastoma (HP:0002885)2.42087943
43Thrombocytosis (HP:0001894)2.40522851
44Abnormality of the carotid arteries (HP:0005344)2.39940997
45Optic nerve coloboma (HP:0000588)2.39568321
46Lymphoma (HP:0002665)2.39322590
47Abnormality of the labia minora (HP:0012880)2.37568440
4811 pairs of ribs (HP:0000878)2.36857792
49Biliary tract neoplasm (HP:0100574)2.36748777
50Mediastinal lymphadenopathy (HP:0100721)2.32223447
51Absent forearm bone (HP:0003953)2.31561367
52Aplasia involving forearm bones (HP:0009822)2.31561367
53Progressive sensorineural hearing impairment (HP:0000408)2.30223215
54Recurrent abscess formation (HP:0002722)2.30169774
55Horseshoe kidney (HP:0000085)2.29602094
56Short middle phalanx of the 5th finger (HP:0004220)2.29325003
57Spinal muscular atrophy (HP:0007269)2.29285129
58Neoplasm of the colon (HP:0100273)2.27746867
59Ureteral duplication (HP:0000073)2.23365544
60Abnormal trabecular bone morphology (HP:0100671)2.23209349
61Abnormality of the duodenum (HP:0002246)2.22993515
62Abnormality of the left ventricular outflow tract (HP:0011103)2.22959233
63Subaortic stenosis (HP:0001682)2.22959233
64Ependymoma (HP:0002888)2.20627700
65Abnormality of pyrimidine metabolism (HP:0004353)2.20201788
66IgM deficiency (HP:0002850)2.19970116
67Tracheoesophageal fistula (HP:0002575)2.18456653
68Fair hair (HP:0002286)2.17374580
69Recurrent bacterial skin infections (HP:0005406)2.17120635
70Abnormality of chromosome segregation (HP:0002916)2.15334898
71Abnormality of the pons (HP:0007361)2.14048063
72Neoplasm of the adrenal cortex (HP:0100641)2.13482939
73Leukopenia (HP:0001882)2.12970693
74Prominent nose (HP:0000448)2.12575104
75Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.09834822
76Abnormality of alanine metabolism (HP:0010916)2.09834822
77Hyperalaninemia (HP:0003348)2.09834822
78Carpal bone hypoplasia (HP:0001498)2.09420349
79Rhabdomyosarcoma (HP:0002859)2.08639886
80Progressive external ophthalmoplegia (HP:0000590)2.08062458
81Amaurosis fugax (HP:0100576)2.07982823
82Neoplasm of the pancreas (HP:0002894)2.07860068
83Multiple enchondromatosis (HP:0005701)2.07174842
84Prostate neoplasm (HP:0100787)2.06229292
85Supernumerary spleens (HP:0009799)2.04799583
86Cellular immunodeficiency (HP:0005374)2.03195176
87Breast carcinoma (HP:0003002)2.02727298
88Selective tooth agenesis (HP:0001592)2.02539888
89Abnormality of methionine metabolism (HP:0010901)2.02125727
90Sandal gap (HP:0001852)2.01705951
91Neoplasm of the small intestine (HP:0100833)2.00533256
92Glioma (HP:0009733)1.98731912
93Acute lymphatic leukemia (HP:0006721)1.98210100
94Triphalangeal thumb (HP:0001199)1.98069287
95Short thumb (HP:0009778)1.97813130
96Abnormal biliary tract morphology (HP:0012440)1.96496959
97Cystic hygroma (HP:0000476)1.96398170
98Hypoplasia of the pons (HP:0012110)1.94662580
99Thyroid carcinoma (HP:0002890)1.92418785
100Renal cortical cysts (HP:0000803)1.91417419
101Increased hepatocellular lipid droplets (HP:0006565)1.90700847
102Pancytopenia (HP:0001876)1.90491029
103Macrocytic anemia (HP:0001972)1.90132030
104Embryonal neoplasm (HP:0002898)1.88361417
105Abnormality of lateral ventricle (HP:0030047)1.86793953
106Abnormality of B cell number (HP:0010975)1.84865781
107B lymphocytopenia (HP:0010976)1.84865781
108Pulmonary fibrosis (HP:0002206)1.84812558
109Abnormality of the heme biosynthetic pathway (HP:0010472)1.84104540
110Pancreatic cysts (HP:0001737)1.83782090
111Abnormality of the prostate (HP:0008775)1.83463052
112Increased nuchal translucency (HP:0010880)1.82962293
113Cafe-au-lait spot (HP:0000957)1.82548276
114Proximal placement of thumb (HP:0009623)1.82374188
115Pancreatic fibrosis (HP:0100732)1.82267564
116Progressive muscle weakness (HP:0003323)1.81219530
117Gonadotropin excess (HP:0000837)1.81139297
118Lipid accumulation in hepatocytes (HP:0006561)1.81020775
119Progressive hearing impairment (HP:0001730)1.80395200
120Entropion (HP:0000621)1.79999304
121Deviation of the thumb (HP:0009603)1.79234782
122Recurrent viral infections (HP:0004429)1.75595574
123Abnormality of the columella (HP:0009929)1.75181056
124Sensory axonal neuropathy (HP:0003390)1.74584562
125Facial cleft (HP:0002006)1.74479398
126Aplasia/Hypoplasia of the tibia (HP:0005772)1.74423369
127Stomatitis (HP:0010280)1.74152755
128Bifid tongue (HP:0010297)1.73379523
129Basal cell carcinoma (HP:0002671)1.71795717
130Abnormality of the septum pellucidum (HP:0007375)1.71237624
131Abnormal spermatogenesis (HP:0008669)1.69887475
132Truncal obesity (HP:0001956)1.69057293
133Abnormal auditory evoked potentials (HP:0006958)1.67152685
134Ovarian neoplasm (HP:0100615)1.66531380
135Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.66144467
136Choanal atresia (HP:0000453)1.66114695
137Microglossia (HP:0000171)1.64686103
138Deep philtrum (HP:0002002)1.64681405
139Nephroblastoma (Wilms tumor) (HP:0002667)1.64448113
140Nemaline bodies (HP:0003798)1.64402177
141Abnormal number of incisors (HP:0011064)1.64156154
142Cutis marmorata (HP:0000965)1.63533990
143Short chin (HP:0000331)1.63266386
144Neoplasm of the oral cavity (HP:0100649)1.63024219
145Uterine neoplasm (HP:0010784)1.62993566
146Spinal cord lesions (HP:0100561)1.62148301
147Syringomyelia (HP:0003396)1.62148301
148Microvesicular hepatic steatosis (HP:0001414)1.61898897
149Abnormality of the astrocytes (HP:0100707)1.59307581
150Astrocytoma (HP:0009592)1.59307581
151Median cleft lip (HP:0000161)1.58503574
152Short tibia (HP:0005736)1.58341423
153Low anterior hairline (HP:0000294)1.57715136
154Capillary hemangiomas (HP:0005306)1.57595980
155Arteriovenous malformation (HP:0100026)1.55824477
156Pancreatic islet-cell hyperplasia (HP:0004510)1.54006522
157Aplasia/Hypoplasia of the sternum (HP:0006714)1.53996341
158Premature ovarian failure (HP:0008209)1.53505668
159Neoplasm of the rectum (HP:0100743)1.53081160

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRSK23.88801220
2WEE13.82184033
3CDC73.61679334
4IRAK43.36079653
5BUB13.15210591
6SRPK13.04934771
7EIF2AK13.01675322
8ACVR1B2.34200150
9TSSK62.31823202
10MKNK22.24012320
11PBK2.17609674
12NEK22.10082430
13MKNK12.09226267
14TTK2.02495716
15NME22.00691152
16VRK11.99540358
17EIF2AK31.98448923
18IRAK31.96232852
19PLK31.90229932
20PLK11.86526548
21ATR1.84728542
22TAF11.81495137
23PLK41.79312886
24TRIM281.78639569
25BRSK11.76061011
26RPS6KA41.72868527
27ZAK1.71613387
28CDK121.68953987
29CHEK21.60595165
30AURKB1.60423111
31BMPR1B1.58245156
32FLT31.57872485
33TNIK1.54711251
34STK391.47698299
35TLK11.42385100
36DYRK31.37120835
37KIT1.36401299
38FRK1.34662575
39MARK31.25051949
40CDK71.20285107
41STK38L1.19644991
42NEK11.17963539
43TXK1.16482962
44CHEK11.16198417
45LATS11.15658916
46TEC1.15418112
47PIM11.10156250
48RPS6KB21.09593101
49STK241.08734335
50CCNB11.06792173
51STK161.06502228
52PASK1.05701703
53MAP4K11.05536758
54CDK41.05133373
55STK101.05053112
56ATM1.05000822
57MST1R1.04434018
58CDK61.04156803
59SCYL21.00541723
60MAP3K140.98842798
61STK40.97587832
62PIM20.97281573
63BMPR20.89352327
64MAP3K80.88267441
65FGFR10.87115629
66ERBB40.87064833
67YES10.82897913
68TAOK30.80326086
69TESK20.80168187
70CDK20.80081602
71BRD40.80050381
72OBSCN0.79014965
73MELK0.77412339
74ALK0.77161782
75BCR0.76358598
76TGFBR10.76013418
77NEK60.75619211
78EIF2AK20.75309028
79AURKA0.74937323
80NLK0.73710637
81CSF1R0.71320211
82PLK20.70733540
83JAK30.66278910
84EPHA20.62788797
85VRK20.62101622
86BLK0.62090923
87ZAP700.61688124
88CDK30.60678309
89CSNK2A20.60085116
90WNK40.59209571
91CDK10.58855525
92PDK20.58644856
93CHUK0.57255769
94IKBKB0.55723802
95CSNK2A10.55610706
96CSNK1E0.54964975
97RPS6KA50.54924995
98WNK30.54249741
99STK30.54236531
100NEK90.53622861
101MAP3K120.52467536
102NME10.51913081
103CLK10.51056858
104CDK80.48118210
105TRPM70.47609883
106PNCK0.45807119
107BTK0.43349551
108PRKDC0.42221532
109EEF2K0.40679681
110PDK40.39914693
111PDK30.39914693
112MET0.37546782
113CSNK1A1L0.36887462
114LYN0.35700659
115CSNK1D0.35657479
116OXSR10.35024975
117AKT30.33890136
118MAPK140.33467742
119LCK0.32286542
120ERBB30.32111229
121SIK30.31166581
122WNK10.30848963
123MAP3K40.30590808
124MAP3K100.30513733
125CSNK1G10.30126269
126RPS6KA60.29884310
127NUAK10.29778606
128PAK10.29318440
129MST40.28150716
130MAPKAPK20.28013723
131PRKCI0.25160501
132PAK40.24396911
133CDK90.24201566
134RPS6KB10.22972403
135AKT10.21999931
136RPS6KC10.21801464

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.33421296
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.88219397
3Mismatch repair_Homo sapiens_hsa034303.70024908
4RNA transport_Homo sapiens_hsa030133.22441383
5Spliceosome_Homo sapiens_hsa030403.09501320
6Homologous recombination_Homo sapiens_hsa034403.08458673
7RNA polymerase_Homo sapiens_hsa030202.88551492
8Non-homologous end-joining_Homo sapiens_hsa034502.86476828
9Fanconi anemia pathway_Homo sapiens_hsa034602.86354457
10Cell cycle_Homo sapiens_hsa041102.80969194
11Base excision repair_Homo sapiens_hsa034102.80178608
12Ribosome_Homo sapiens_hsa030102.62003686
13One carbon pool by folate_Homo sapiens_hsa006702.58086154
14Nucleotide excision repair_Homo sapiens_hsa034202.50471658
15Proteasome_Homo sapiens_hsa030502.11966332
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.11257974
17Pyrimidine metabolism_Homo sapiens_hsa002402.08577874
18RNA degradation_Homo sapiens_hsa030182.06992540
19Basal transcription factors_Homo sapiens_hsa030221.94445032
20p53 signaling pathway_Homo sapiens_hsa041151.75009136
21mRNA surveillance pathway_Homo sapiens_hsa030151.72498088
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.57127825
23Antigen processing and presentation_Homo sapiens_hsa046121.42115496
24Propanoate metabolism_Homo sapiens_hsa006401.37508264
25Epstein-Barr virus infection_Homo sapiens_hsa051691.36128635
26Systemic lupus erythematosus_Homo sapiens_hsa053221.29407565
27Herpes simplex infection_Homo sapiens_hsa051681.24987940
28Circadian rhythm_Homo sapiens_hsa047101.23776456
29Purine metabolism_Homo sapiens_hsa002301.20017768
30NF-kappa B signaling pathway_Homo sapiens_hsa040641.12971296
31Viral carcinogenesis_Homo sapiens_hsa052031.09055157
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06696847
33Primary immunodeficiency_Homo sapiens_hsa053401.05929585
34NOD-like receptor signaling pathway_Homo sapiens_hsa046211.04774139
35Measles_Homo sapiens_hsa051621.04313804
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.98427818
37Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97549329
38Oocyte meiosis_Homo sapiens_hsa041140.96119053
39Pyruvate metabolism_Homo sapiens_hsa006200.90058848
40MicroRNAs in cancer_Homo sapiens_hsa052060.85040417
41Transcriptional misregulation in cancer_Homo sapiens_hsa052020.83609018
42Legionellosis_Homo sapiens_hsa051340.81706022
43Lysine degradation_Homo sapiens_hsa003100.79882664
44HTLV-I infection_Homo sapiens_hsa051660.78829520
45Leishmaniasis_Homo sapiens_hsa051400.78589533
46Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.75077743
47Vitamin B6 metabolism_Homo sapiens_hsa007500.74693954
48Hematopoietic cell lineage_Homo sapiens_hsa046400.74619251
49Protein export_Homo sapiens_hsa030600.70684396
50Small cell lung cancer_Homo sapiens_hsa052220.69663479
51Apoptosis_Homo sapiens_hsa042100.68801923
52Hepatitis B_Homo sapiens_hsa051610.66896778
53Influenza A_Homo sapiens_hsa051640.65704959
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64461646
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61937206
56Allograft rejection_Homo sapiens_hsa053300.60390779
57Intestinal immune network for IgA production_Homo sapiens_hsa046720.59621964
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59134699
59RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.57416448
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.56626852
61Hippo signaling pathway_Homo sapiens_hsa043900.55228892
62Caffeine metabolism_Homo sapiens_hsa002320.53586193
63Adherens junction_Homo sapiens_hsa045200.53030260
64Huntingtons disease_Homo sapiens_hsa050160.52935263
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51867926
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51802302
67Wnt signaling pathway_Homo sapiens_hsa043100.51599781
68Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51168757
69B cell receptor signaling pathway_Homo sapiens_hsa046620.50722035
70Graft-versus-host disease_Homo sapiens_hsa053320.50287465
71Thyroid cancer_Homo sapiens_hsa052160.49607630
72Pentose phosphate pathway_Homo sapiens_hsa000300.49406547
73Shigellosis_Homo sapiens_hsa051310.48559225
74Selenocompound metabolism_Homo sapiens_hsa004500.47853209
75Folate biosynthesis_Homo sapiens_hsa007900.46726827
76Asthma_Homo sapiens_hsa053100.46464883
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.46256653
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.46198430
79Acute myeloid leukemia_Homo sapiens_hsa052210.45896105
80Chronic myeloid leukemia_Homo sapiens_hsa052200.45436716
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45283144
82Colorectal cancer_Homo sapiens_hsa052100.44982594
83Prostate cancer_Homo sapiens_hsa052150.41192232
84Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.40472213
85Tuberculosis_Homo sapiens_hsa051520.40173775
86HIF-1 signaling pathway_Homo sapiens_hsa040660.38562823
87Toll-like receptor signaling pathway_Homo sapiens_hsa046200.38396364
88Pertussis_Homo sapiens_hsa051330.37986505
89Alcoholism_Homo sapiens_hsa050340.37845267
90Osteoclast differentiation_Homo sapiens_hsa043800.36099117
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.35773104
92Renin-angiotensin system_Homo sapiens_hsa046140.35725608
93T cell receptor signaling pathway_Homo sapiens_hsa046600.35439791
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.34545161
95Type I diabetes mellitus_Homo sapiens_hsa049400.34170559
96Toxoplasmosis_Homo sapiens_hsa051450.32466509
97Parkinsons disease_Homo sapiens_hsa050120.31482960
98Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.31380030
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.30290084
100N-Glycan biosynthesis_Homo sapiens_hsa005100.29952932
101FoxO signaling pathway_Homo sapiens_hsa040680.29170338
102Steroid biosynthesis_Homo sapiens_hsa001000.28842066
103Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.28556013
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.27922522
105Oxidative phosphorylation_Homo sapiens_hsa001900.27320533
106Regulation of autophagy_Homo sapiens_hsa041400.27136826
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.27089695
108Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25498213
109Fatty acid biosynthesis_Homo sapiens_hsa000610.24833549
110Viral myocarditis_Homo sapiens_hsa054160.24151057
111Carbon metabolism_Homo sapiens_hsa012000.23793398
112TNF signaling pathway_Homo sapiens_hsa046680.23354232
113Neurotrophin signaling pathway_Homo sapiens_hsa047220.22656081
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.21791621
115TGF-beta signaling pathway_Homo sapiens_hsa043500.21476158
116Pathways in cancer_Homo sapiens_hsa052000.21138744
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.20822517
118Hedgehog signaling pathway_Homo sapiens_hsa043400.20543064
119Basal cell carcinoma_Homo sapiens_hsa052170.20454562
120Pancreatic cancer_Homo sapiens_hsa052120.20266895
121Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.19884269
122Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.19530047
123Non-small cell lung cancer_Homo sapiens_hsa052230.18876538
124mTOR signaling pathway_Homo sapiens_hsa041500.18608711
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.18476424
126Melanoma_Homo sapiens_hsa052180.17810468
127Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.17437648
128Biosynthesis of amino acids_Homo sapiens_hsa012300.16687383
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.16438203
130Metabolic pathways_Homo sapiens_hsa011000.16410701
131Dorso-ventral axis formation_Homo sapiens_hsa043200.16314823
132Maturity onset diabetes of the young_Homo sapiens_hsa049500.15705458
133Inositol phosphate metabolism_Homo sapiens_hsa005620.13481750
134Butanoate metabolism_Homo sapiens_hsa006500.12551620
135Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.11447218
136Sulfur metabolism_Homo sapiens_hsa009200.11404782
137Proteoglycans in cancer_Homo sapiens_hsa052050.10542333
138Alzheimers disease_Homo sapiens_hsa050100.10127942
139Nitrogen metabolism_Homo sapiens_hsa009100.08686740
140Olfactory transduction_Homo sapiens_hsa047400.08526211

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