

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | gonadal mesoderm development (GO:0007506) | 6.72679031 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.47915336 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.13244826 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.13244826 |
| 5 | proteasome assembly (GO:0043248) | 5.01803969 |
| 6 | rRNA modification (GO:0000154) | 4.79891912 |
| 7 | maturation of SSU-rRNA (GO:0030490) | 4.65584236 |
| 8 | rRNA methylation (GO:0031167) | 4.65222664 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 4.63013243 |
| 10 | viral transcription (GO:0019083) | 4.57272462 |
| 11 | translational termination (GO:0006415) | 4.55050527 |
| 12 | ribosomal small subunit biogenesis (GO:0042274) | 4.42929397 |
| 13 | hepatocyte apoptotic process (GO:0097284) | 4.42438533 |
| 14 | chaperone-mediated protein transport (GO:0072321) | 4.19490606 |
| 15 | ribosome assembly (GO:0042255) | 4.19001950 |
| 16 | ribosomal large subunit biogenesis (GO:0042273) | 4.17920435 |
| 17 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.13088185 |
| 18 | regulation of cellular respiration (GO:0043457) | 4.09025124 |
| 19 | respiratory electron transport chain (GO:0022904) | 4.07932281 |
| 20 | single strand break repair (GO:0000012) | 4.04471136 |
| 21 | electron transport chain (GO:0022900) | 4.00122138 |
| 22 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.99518623 |
| 23 | regulation of oxidative phosphorylation (GO:0002082) | 3.95122947 |
| 24 | translational elongation (GO:0006414) | 3.93342735 |
| 25 | cotranslational protein targeting to membrane (GO:0006613) | 3.91148858 |
| 26 | protein targeting to ER (GO:0045047) | 3.86417574 |
| 27 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.73131841 |
| 28 | translation (GO:0006412) | 3.72553159 |
| 29 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.71360885 |
| 30 | protein localization to endoplasmic reticulum (GO:0070972) | 3.71190504 |
| 31 | regulation of mitochondrial translation (GO:0070129) | 3.60420529 |
| 32 | cellular protein complex disassembly (GO:0043624) | 3.58768339 |
| 33 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.58736512 |
| 34 | translational initiation (GO:0006413) | 3.56179654 |
| 35 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.53155353 |
| 36 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.53155353 |
| 37 | viral life cycle (GO:0019058) | 3.47801081 |
| 38 | hydrogen ion transmembrane transport (GO:1902600) | 3.33393842 |
| 39 | regulation of centriole replication (GO:0046599) | 3.33158750 |
| 40 | negative regulation of complement activation (GO:0045916) | 3.32461815 |
| 41 | prostanoid biosynthetic process (GO:0046457) | 3.25390009 |
| 42 | prostaglandin biosynthetic process (GO:0001516) | 3.25390009 |
| 43 | intestinal epithelial cell development (GO:0060576) | 3.23981550 |
| 44 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.23551393 |
| 45 | ATP biosynthetic process (GO:0006754) | 3.22399308 |
| 46 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.17770337 |
| 47 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.16912030 |
| 48 | DNA replication checkpoint (GO:0000076) | 3.16880057 |
| 49 | histone mRNA metabolic process (GO:0008334) | 3.16183944 |
| 50 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.14833274 |
| 51 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.14438378 |
| 52 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.13301515 |
| 53 | rRNA processing (GO:0006364) | 3.10932772 |
| 54 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.09824824 |
| 55 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.09724896 |
| 56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.08215814 |
| 57 | protein complex disassembly (GO:0043241) | 3.05271461 |
| 58 | sperm motility (GO:0030317) | 3.04158339 |
| 59 | galactose catabolic process (GO:0019388) | 3.03683282 |
| 60 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.99519511 |
| 61 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.99519511 |
| 62 | spliceosomal complex assembly (GO:0000245) | 2.99510718 |
| 63 | rRNA metabolic process (GO:0016072) | 2.97225671 |
| 64 | artery smooth muscle contraction (GO:0014824) | 2.96526568 |
| 65 | mitotic metaphase plate congression (GO:0007080) | 2.95010795 |
| 66 | spliceosomal snRNP assembly (GO:0000387) | 2.94966646 |
| 67 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.94556111 |
| 68 | negative regulation of ligase activity (GO:0051352) | 2.94556111 |
| 69 | cellular component biogenesis (GO:0044085) | 2.94167106 |
| 70 | protein targeting to mitochondrion (GO:0006626) | 2.93808116 |
| 71 | macromolecular complex disassembly (GO:0032984) | 2.92110125 |
| 72 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.91012600 |
| 73 | peptidyl-histidine modification (GO:0018202) | 2.90361893 |
| 74 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.90024597 |
| 75 | protein targeting to membrane (GO:0006612) | 2.87582201 |
| 76 | proton transport (GO:0015992) | 2.87063519 |
| 77 | negative regulation of protein activation cascade (GO:2000258) | 2.85956773 |
| 78 | regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) | 2.85634510 |
| 79 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.84692332 |
| 80 | oxidative phosphorylation (GO:0006119) | 2.83737993 |
| 81 | protein localization to mitochondrion (GO:0070585) | 2.83366662 |
| 82 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.82729257 |
| 83 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.81141292 |
| 84 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.80392541 |
| 85 | hydrogen transport (GO:0006818) | 2.79851399 |
| 86 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.79285965 |
| 87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.77761445 |
| 88 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.77761445 |
| 89 | DNA damage response, detection of DNA damage (GO:0042769) | 2.75861329 |
| 90 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.74303586 |
| 91 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.74303586 |
| 92 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.74303586 |
| 93 | positive regulation of ligase activity (GO:0051351) | 2.73754154 |
| 94 | establishment of protein localization to mitochondrion (GO:0072655) | 2.70454379 |
| 95 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.70343864 |
| 96 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.70343864 |
| 97 | GTP biosynthetic process (GO:0006183) | 2.70005623 |
| 98 | base-excision repair, AP site formation (GO:0006285) | 2.69319023 |
| 99 | chromosome condensation (GO:0030261) | 2.65062624 |
| 100 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.64718633 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.41767435 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21715268 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.12871504 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.60203676 |
| 5 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.49252024 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.34068086 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.18717556 |
| 8 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.18343093 |
| 9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.05467691 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.03865246 |
| 11 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.92124504 |
| 12 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.91218622 |
| 13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.87223632 |
| 14 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.76238564 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.73841610 |
| 16 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.64913856 |
| 17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.60366876 |
| 18 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.35861817 |
| 19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.26365494 |
| 20 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.24370125 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.14897685 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.10296192 |
| 23 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.09416121 |
| 24 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.06549509 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.04267423 |
| 26 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.02178810 |
| 27 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.00330121 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.97683106 |
| 29 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.95412370 |
| 30 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.94272191 |
| 31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.92772869 |
| 32 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.81949847 |
| 33 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.80374291 |
| 34 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.70541467 |
| 35 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.67896548 |
| 36 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.57469915 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.57104502 |
| 38 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.56418188 |
| 39 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.56294555 |
| 40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.55879741 |
| 41 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.54373218 |
| 42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52883294 |
| 43 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.52622567 |
| 44 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.47746036 |
| 45 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.45190847 |
| 46 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.43023086 |
| 47 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.42533387 |
| 48 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.39458064 |
| 49 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.37968114 |
| 50 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.31302073 |
| 51 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.27661705 |
| 52 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.26958273 |
| 53 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.25931143 |
| 54 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.25439594 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.24296618 |
| 56 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.23093546 |
| 57 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.23007694 |
| 58 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.21857168 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.20735507 |
| 60 | ATF3_27146783_Chip-Seq_COLON_Human | 1.19911925 |
| 61 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.18365583 |
| 62 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.16162351 |
| 63 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.12299480 |
| 64 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.10900022 |
| 65 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.09577161 |
| 66 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09233555 |
| 67 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.08749826 |
| 68 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.04645417 |
| 69 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.03531006 |
| 70 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.01566979 |
| 71 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.01545230 |
| 72 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.99949416 |
| 73 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.99902728 |
| 74 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.99093214 |
| 75 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.97450772 |
| 76 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.97316490 |
| 77 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.97159450 |
| 78 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.96292431 |
| 79 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.96260797 |
| 80 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.95931820 |
| 81 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.95237841 |
| 82 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.94960517 |
| 83 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90810968 |
| 84 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.90199266 |
| 85 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.90070226 |
| 86 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89792967 |
| 87 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89558376 |
| 88 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.87763580 |
| 89 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.86710145 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.85615648 |
| 91 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.84339224 |
| 92 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.83611952 |
| 93 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.83155860 |
| 94 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.82284055 |
| 95 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.81018504 |
| 96 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.79718307 |
| 97 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.79304385 |
| 98 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.78905593 |
| 99 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.76103655 |
| 100 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.75802892 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.79627874 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 4.45886182 |
| 3 | MP0005410_abnormal_fertilization | 3.24787765 |
| 4 | MP0005377_hearing/vestibular/ear_phenot | 3.17410466 |
| 5 | MP0003878_abnormal_ear_physiology | 3.17410466 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 3.16536539 |
| 7 | MP0003693_abnormal_embryo_hatching | 3.16286110 |
| 8 | MP0008995_early_reproductive_senescence | 2.57984052 |
| 9 | MP0002254_reproductive_system_inflammat | 2.45588058 |
| 10 | MP0000516_abnormal_urinary_system | 2.38220547 |
| 11 | MP0005367_renal/urinary_system_phenotyp | 2.38220547 |
| 12 | MP0000566_synostosis | 2.22509974 |
| 13 | MP0000537_abnormal_urethra_morphology | 2.17266547 |
| 14 | MP0002796_impaired_skin_barrier | 2.09444461 |
| 15 | MP0005670_abnormal_white_adipose | 2.09069634 |
| 16 | MP0010234_abnormal_vibrissa_follicle | 2.08925118 |
| 17 | MP0008877_abnormal_DNA_methylation | 1.95918547 |
| 18 | MP0003077_abnormal_cell_cycle | 1.85017645 |
| 19 | MP0008058_abnormal_DNA_repair | 1.83845588 |
| 20 | MP0003718_maternal_effect | 1.81143014 |
| 21 | MP0003786_premature_aging | 1.73517660 |
| 22 | MP0004019_abnormal_vitamin_homeostasis | 1.70833144 |
| 23 | MP0006036_abnormal_mitochondrial_physio | 1.65079306 |
| 24 | MP0004264_abnormal_extraembryonic_tissu | 1.62614480 |
| 25 | MP0005501_abnormal_skin_physiology | 1.60514003 |
| 26 | MP0003111_abnormal_nucleus_morphology | 1.51589760 |
| 27 | MP0001929_abnormal_gametogenesis | 1.49862769 |
| 28 | MP0003186_abnormal_redox_activity | 1.49762125 |
| 29 | MP0003011_delayed_dark_adaptation | 1.46685672 |
| 30 | MP0002098_abnormal_vibrissa_morphology | 1.46530010 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.44768919 |
| 32 | MP0010678_abnormal_skin_adnexa | 1.43215995 |
| 33 | MP0000358_abnormal_cell_content/ | 1.41930161 |
| 34 | MP0010094_abnormal_chromosome_stability | 1.41084912 |
| 35 | MP0002837_dystrophic_cardiac_calcinosis | 1.39471792 |
| 36 | MP0001756_abnormal_urination | 1.38662008 |
| 37 | MP0000383_abnormal_hair_follicle | 1.37997559 |
| 38 | MP0005408_hypopigmentation | 1.35773261 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.34577601 |
| 40 | MP0001727_abnormal_embryo_implantation | 1.34254171 |
| 41 | MP0001697_abnormal_embryo_size | 1.30990777 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.27453517 |
| 43 | MP0001666_abnormal_nutrient_absorption | 1.26042012 |
| 44 | MP0003698_abnormal_male_reproductive | 1.25130713 |
| 45 | MP0008932_abnormal_embryonic_tissue | 1.23512528 |
| 46 | MP0008872_abnormal_physiological_respon | 1.22523876 |
| 47 | MP0003638_abnormal_response/metabolism_ | 1.20711712 |
| 48 | MP0002210_abnormal_sex_determination | 1.19893646 |
| 49 | MP0001346_abnormal_lacrimal_gland | 1.19104940 |
| 50 | MP0002139_abnormal_hepatobiliary_system | 1.18613990 |
| 51 | MP0005084_abnormal_gallbladder_morpholo | 1.18156865 |
| 52 | MP0000647_abnormal_sebaceous_gland | 1.17528883 |
| 53 | MP0001293_anophthalmia | 1.17259800 |
| 54 | MP0005360_urolithiasis | 1.12472917 |
| 55 | MP0006054_spinal_hemorrhage | 1.11411500 |
| 56 | MP0005332_abnormal_amino_acid | 1.10338852 |
| 57 | MP0010030_abnormal_orbit_morphology | 1.09699292 |
| 58 | MP0003315_abnormal_perineum_morphology | 1.04295345 |
| 59 | MP0009643_abnormal_urine_homeostasis | 1.02367216 |
| 60 | MP0000350_abnormal_cell_proliferation | 1.02022632 |
| 61 | MP0001881_abnormal_mammary_gland | 1.01764167 |
| 62 | MP0002234_abnormal_pharynx_morphology | 1.00989230 |
| 63 | MP0000427_abnormal_hair_cycle | 0.99474262 |
| 64 | MP0000627_abnormal_mammary_gland | 0.99426247 |
| 65 | MP0003936_abnormal_reproductive_system | 0.98427565 |
| 66 | MP0002085_abnormal_embryonic_tissue | 0.95860521 |
| 67 | MP0001968_abnormal_touch/_nociception | 0.95213542 |
| 68 | MP0001145_abnormal_male_reproductive | 0.94250930 |
| 69 | MP0005380_embryogenesis_phenotype | 0.93826273 |
| 70 | MP0001672_abnormal_embryogenesis/_devel | 0.93826273 |
| 71 | MP0004147_increased_porphyrin_level | 0.92593496 |
| 72 | MP0002088_abnormal_embryonic_growth/wei | 0.89632103 |
| 73 | MP0003984_embryonic_growth_retardation | 0.88285555 |
| 74 | MP0001730_embryonic_growth_arrest | 0.85815115 |
| 75 | MP0005636_abnormal_mineral_homeostasis | 0.85725982 |
| 76 | MP0004782_abnormal_surfactant_physiolog | 0.84936296 |
| 77 | MP0010771_integument_phenotype | 0.84157048 |
| 78 | MP0000653_abnormal_sex_gland | 0.83946893 |
| 79 | MP0000049_abnormal_middle_ear | 0.83389150 |
| 80 | MP0002161_abnormal_fertility/fecundity | 0.82899433 |
| 81 | MP0002080_prenatal_lethality | 0.81921955 |
| 82 | MP0004233_abnormal_muscle_weight | 0.81002335 |
| 83 | MP0003252_abnormal_bile_duct | 0.80903219 |
| 84 | MP0002177_abnormal_outer_ear | 0.80635260 |
| 85 | MP0000467_abnormal_esophagus_morphology | 0.79936909 |
| 86 | MP0003937_abnormal_limbs/digits/tail_de | 0.77003009 |
| 87 | MP0003941_abnormal_skin_development | 0.75160082 |
| 88 | MP0001188_hyperpigmentation | 0.73669504 |
| 89 | MP0000762_abnormal_tongue_morphology | 0.72987785 |
| 90 | MP0003123_paternal_imprinting | 0.71781582 |
| 91 | MP0000313_abnormal_cell_death | 0.70739796 |
| 92 | MP0001485_abnormal_pinna_reflex | 0.68466980 |
| 93 | MP0002136_abnormal_kidney_physiology | 0.67583605 |
| 94 | MP0001286_abnormal_eye_development | 0.66884117 |
| 95 | MP0008007_abnormal_cellular_replicative | 0.66415914 |
| 96 | MP0002111_abnormal_tail_morphology | 0.65878004 |
| 97 | MP0003943_abnormal_hepatobiliary_system | 0.65157364 |
| 98 | MP0005075_abnormal_melanosome_morpholog | 0.64977555 |
| 99 | MP0002160_abnormal_reproductive_system | 0.64611488 |
| 100 | MP0002938_white_spotting | 0.63623942 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.87206590 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.68777761 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.67648675 |
| 4 | Acute encephalopathy (HP:0006846) | 4.53823091 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.33991255 |
| 6 | Hepatic necrosis (HP:0002605) | 4.19458721 |
| 7 | Micronodular cirrhosis (HP:0001413) | 4.19316757 |
| 8 | Increased CSF lactate (HP:0002490) | 4.12245567 |
| 9 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.88719294 |
| 10 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.88719294 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.84927963 |
| 12 | Stenosis of the external auditory canal (HP:0000402) | 3.79723152 |
| 13 | Reticulocytopenia (HP:0001896) | 3.46224583 |
| 14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.42100043 |
| 15 | Macrocytic anemia (HP:0001972) | 3.15951426 |
| 16 | Cerebral edema (HP:0002181) | 3.15475908 |
| 17 | Glycosuria (HP:0003076) | 3.05537680 |
| 18 | Abnormality of urine glucose concentration (HP:0011016) | 3.05537680 |
| 19 | Male infertility (HP:0003251) | 3.04157372 |
| 20 | Generalized aminoaciduria (HP:0002909) | 3.01536421 |
| 21 | Renal Fanconi syndrome (HP:0001994) | 2.94757908 |
| 22 | Lactic acidosis (HP:0003128) | 2.87888174 |
| 23 | Abnormal number of erythroid precursors (HP:0012131) | 2.86225128 |
| 24 | Abnormality of magnesium homeostasis (HP:0004921) | 2.84823433 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.80968754 |
| 26 | Proximal tubulopathy (HP:0000114) | 2.74305717 |
| 27 | Cone-rod dystrophy (HP:0000548) | 2.67890838 |
| 28 | Lipid accumulation in hepatocytes (HP:0006561) | 2.67440739 |
| 29 | Optic disc pallor (HP:0000543) | 2.62931313 |
| 30 | Increased serum lactate (HP:0002151) | 2.62808639 |
| 31 | Tetany (HP:0001281) | 2.62792424 |
| 32 | Severe visual impairment (HP:0001141) | 2.59405184 |
| 33 | Amelogenesis imperfecta (HP:0000705) | 2.57839110 |
| 34 | Respiratory failure (HP:0002878) | 2.54574795 |
| 35 | Abnormality of macular pigmentation (HP:0008002) | 2.51257915 |
| 36 | Renal tubular acidosis (HP:0001947) | 2.49029013 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.48896261 |
| 38 | Renal tubular dysfunction (HP:0000124) | 2.47546952 |
| 39 | Leukodystrophy (HP:0002415) | 2.39677927 |
| 40 | Congenital, generalized hypertrichosis (HP:0004540) | 2.38135510 |
| 41 | Exercise intolerance (HP:0003546) | 2.37647591 |
| 42 | Abnormality of the anterior horn cell (HP:0006802) | 2.37221786 |
| 43 | Degeneration of anterior horn cells (HP:0002398) | 2.37221786 |
| 44 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.36256472 |
| 45 | Paralysis (HP:0003470) | 2.34511181 |
| 46 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.28887460 |
| 47 | Type I transferrin isoform profile (HP:0003642) | 2.28545870 |
| 48 | Lethargy (HP:0001254) | 2.28242559 |
| 49 | Hyperglycinemia (HP:0002154) | 2.24115240 |
| 50 | Hypomagnesemia (HP:0002917) | 2.23168455 |
| 51 | Increased circulating renin level (HP:0000848) | 2.22826456 |
| 52 | Facial cleft (HP:0002006) | 2.22248802 |
| 53 | Nausea (HP:0002018) | 2.19798452 |
| 54 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.19647059 |
| 55 | Sensory axonal neuropathy (HP:0003390) | 2.19164463 |
| 56 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.19044121 |
| 57 | Concave nail (HP:0001598) | 2.16335857 |
| 58 | Increased muscle lipid content (HP:0009058) | 2.10700795 |
| 59 | Abnormality of renal resorption (HP:0011038) | 2.08854717 |
| 60 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.05337493 |
| 61 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.03290876 |
| 62 | Sclerocornea (HP:0000647) | 2.00943444 |
| 63 | Polydipsia (HP:0001959) | 2.00818624 |
| 64 | Abnormal drinking behavior (HP:0030082) | 2.00818624 |
| 65 | Ureteral duplication (HP:0000073) | 1.98545364 |
| 66 | Scotoma (HP:0000575) | 1.98344704 |
| 67 | Subcapsular cataract (HP:0000523) | 1.95774741 |
| 68 | CNS demyelination (HP:0007305) | 1.95065749 |
| 69 | Abnormality of dental color (HP:0011073) | 1.94029500 |
| 70 | Congenital malformation of the right heart (HP:0011723) | 1.93806421 |
| 71 | Double outlet right ventricle (HP:0001719) | 1.93806421 |
| 72 | Woolly hair (HP:0002224) | 1.93196811 |
| 73 | Abnormality of the umbilical cord (HP:0010881) | 1.92007594 |
| 74 | Humeroradial synostosis (HP:0003041) | 1.91817012 |
| 75 | Synostosis involving the elbow (HP:0003938) | 1.91817012 |
| 76 | Cerebral palsy (HP:0100021) | 1.90763022 |
| 77 | Exertional dyspnea (HP:0002875) | 1.88207187 |
| 78 | Aplasia cutis congenita (HP:0001057) | 1.87671670 |
| 79 | Amniotic constriction ring (HP:0009775) | 1.87038122 |
| 80 | Abnormality of placental membranes (HP:0011409) | 1.87038122 |
| 81 | Palpitations (HP:0001962) | 1.86737735 |
| 82 | Patent foramen ovale (HP:0001655) | 1.84126936 |
| 83 | Abnormal protein glycosylation (HP:0012346) | 1.83213921 |
| 84 | Abnormal glycosylation (HP:0012345) | 1.83213921 |
| 85 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.83213921 |
| 86 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.83213921 |
| 87 | Birth length less than 3rd percentile (HP:0003561) | 1.81931282 |
| 88 | Abnormal auditory evoked potentials (HP:0006958) | 1.79617188 |
| 89 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.77858111 |
| 90 | Single umbilical artery (HP:0001195) | 1.77858111 |
| 91 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.77858111 |
| 92 | Upper limb muscle weakness (HP:0003484) | 1.76449343 |
| 93 | Megaloblastic anemia (HP:0001889) | 1.75353309 |
| 94 | Septate vagina (HP:0001153) | 1.73048429 |
| 95 | High anterior hairline (HP:0009890) | 1.71947348 |
| 96 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.70887798 |
| 97 | Hypoparathyroidism (HP:0000829) | 1.70740666 |
| 98 | Seborrheic dermatitis (HP:0001051) | 1.70596326 |
| 99 | Blindness (HP:0000618) | 1.70417487 |
| 100 | Vomiting (HP:0002013) | 1.69974621 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 4.17314867 |
| 2 | EPHA2 | 3.75549727 |
| 3 | PLK4 | 3.46402323 |
| 4 | STK39 | 3.39679354 |
| 5 | ARAF | 3.38042680 |
| 6 | VRK2 | 3.27992898 |
| 7 | PBK | 3.20588975 |
| 8 | MAP3K9 | 3.04048589 |
| 9 | WNK4 | 2.93726793 |
| 10 | OXSR1 | 2.89619572 |
| 11 | NME2 | 2.62365017 |
| 12 | MST4 | 2.46416918 |
| 13 | MYLK | 2.07817689 |
| 14 | MAP3K13 | 1.99066022 |
| 15 | BUB1 | 1.97667288 |
| 16 | MST1R | 1.89262278 |
| 17 | ILK | 1.76345661 |
| 18 | PDK2 | 1.70322550 |
| 19 | BCKDK | 1.67008840 |
| 20 | NEK1 | 1.65569867 |
| 21 | RPS6KB2 | 1.65266164 |
| 22 | CDK19 | 1.57229298 |
| 23 | PAK4 | 1.49580245 |
| 24 | STK16 | 1.45815332 |
| 25 | TESK1 | 1.43072553 |
| 26 | SRPK1 | 1.36092122 |
| 27 | EIF2AK1 | 1.34597232 |
| 28 | CHEK2 | 1.28773396 |
| 29 | BRAF | 1.23780115 |
| 30 | EIF2AK3 | 1.22037008 |
| 31 | CDC7 | 1.17696637 |
| 32 | ABL2 | 1.16629303 |
| 33 | BMPR1B | 1.16424334 |
| 34 | DAPK1 | 1.04844050 |
| 35 | EPHB2 | 0.98940124 |
| 36 | INSRR | 0.97268065 |
| 37 | LATS2 | 0.94161269 |
| 38 | NME1 | 0.91762842 |
| 39 | PLK2 | 0.91379655 |
| 40 | CSNK1G3 | 0.90631698 |
| 41 | TRIM28 | 0.90572953 |
| 42 | VRK1 | 0.89572762 |
| 43 | DAPK3 | 0.88047883 |
| 44 | TESK2 | 0.87937209 |
| 45 | PIM2 | 0.80927449 |
| 46 | PLK1 | 0.80594179 |
| 47 | PNCK | 0.79191608 |
| 48 | CDK8 | 0.78761185 |
| 49 | CDK7 | 0.77391490 |
| 50 | SCYL2 | 0.74659024 |
| 51 | NEK2 | 0.74613923 |
| 52 | AURKB | 0.73938192 |
| 53 | CSNK1A1L | 0.73393042 |
| 54 | MAP3K8 | 0.73158507 |
| 55 | PASK | 0.73086261 |
| 56 | AURKA | 0.71317675 |
| 57 | STK38L | 0.69583031 |
| 58 | CSNK1G1 | 0.68214491 |
| 59 | CAMK2G | 0.68133204 |
| 60 | CSNK1G2 | 0.66097532 |
| 61 | NUAK1 | 0.65492541 |
| 62 | LIMK1 | 0.65441050 |
| 63 | LMTK2 | 0.60933615 |
| 64 | DYRK2 | 0.60696695 |
| 65 | PHKG1 | 0.59907615 |
| 66 | PHKG2 | 0.59907615 |
| 67 | MET | 0.58793398 |
| 68 | PRKCI | 0.51621151 |
| 69 | PINK1 | 0.50232152 |
| 70 | TNIK | 0.49623273 |
| 71 | DYRK3 | 0.48611859 |
| 72 | WNK3 | 0.46997496 |
| 73 | ERBB4 | 0.46943913 |
| 74 | PLK3 | 0.43106292 |
| 75 | PIK3CA | 0.41454801 |
| 76 | NEK6 | 0.40293386 |
| 77 | AKT2 | 0.40111268 |
| 78 | CSNK2A2 | 0.39882960 |
| 79 | GRK1 | 0.39666734 |
| 80 | CDK3 | 0.38931046 |
| 81 | CSNK2A1 | 0.38123332 |
| 82 | ZAK | 0.37803638 |
| 83 | DMPK | 0.37238481 |
| 84 | KDR | 0.37231842 |
| 85 | CHEK1 | 0.36650650 |
| 86 | PRKG2 | 0.36612081 |
| 87 | CAMK2D | 0.36201342 |
| 88 | MOS | 0.35244768 |
| 89 | TSSK6 | 0.34816289 |
| 90 | CSNK1E | 0.33709677 |
| 91 | TAF1 | 0.33427656 |
| 92 | ROCK1 | 0.32180470 |
| 93 | PAK1 | 0.32051809 |
| 94 | FGFR2 | 0.32032225 |
| 95 | IRAK3 | 0.31571830 |
| 96 | TLK1 | 0.29753910 |
| 97 | CSNK1A1 | 0.29674421 |
| 98 | MAP2K7 | 0.28500389 |
| 99 | RPS6KA4 | 0.28325563 |
| 100 | RAF1 | 0.28124721 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.00897117 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.49000741 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.28419386 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.43878413 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.80317940 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.79479919 |
| 7 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.62787250 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.40314806 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.17279994 |
| 10 | DNA replication_Homo sapiens_hsa03030 | 2.12107356 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.11869483 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.10933452 |
| 13 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.09749094 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 1.94617027 |
| 15 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.84131578 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.77940210 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.77199244 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.76171999 |
| 19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.75720511 |
| 20 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.74433137 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.58684050 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.55564908 |
| 23 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.52597364 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.47751509 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.39153783 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.30610307 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.23966548 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.20178808 |
| 29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.20034307 |
| 30 | Sulfur relay system_Homo sapiens_hsa04122 | 1.18321807 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.06929017 |
| 32 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.05108597 |
| 33 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.03522218 |
| 34 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.02292882 |
| 35 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.02158586 |
| 36 | Protein export_Homo sapiens_hsa03060 | 0.99689907 |
| 37 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.93418870 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 0.92715351 |
| 39 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.91800213 |
| 40 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.91533916 |
| 41 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.91247468 |
| 42 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.89414100 |
| 43 | Metabolic pathways_Homo sapiens_hsa01100 | 0.88182701 |
| 44 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.87698299 |
| 45 | Carbon metabolism_Homo sapiens_hsa01200 | 0.87462019 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.85585503 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.85023342 |
| 48 | Galactose metabolism_Homo sapiens_hsa00052 | 0.83556307 |
| 49 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.83396404 |
| 50 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.83141322 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.83139579 |
| 52 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.79404834 |
| 53 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.76010235 |
| 54 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.74417250 |
| 55 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.73284210 |
| 56 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.72990703 |
| 57 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.72024572 |
| 58 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70730694 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70380240 |
| 60 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.68887340 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.67058348 |
| 62 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.64380845 |
| 63 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.62861140 |
| 64 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.59768804 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57614424 |
| 66 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.57395475 |
| 67 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.55624842 |
| 68 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.54395764 |
| 69 | Tight junction_Homo sapiens_hsa04530 | 0.54111756 |
| 70 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52273234 |
| 71 | Bladder cancer_Homo sapiens_hsa05219 | 0.52097012 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51283465 |
| 73 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.51001917 |
| 74 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.48545510 |
| 75 | Cell cycle_Homo sapiens_hsa04110 | 0.47615588 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46986832 |
| 77 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.45844255 |
| 78 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42330468 |
| 79 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.42170496 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.41450604 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39377116 |
| 82 | Bile secretion_Homo sapiens_hsa04976 | 0.36965082 |
| 83 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.36837878 |
| 84 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.36312347 |
| 85 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.36271329 |
| 86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.35525438 |
| 87 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.35288399 |
| 88 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.35121702 |
| 89 | Peroxisome_Homo sapiens_hsa04146 | 0.32764727 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32694528 |
| 91 | Thyroid cancer_Homo sapiens_hsa05216 | 0.32037612 |
| 92 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.29448026 |
| 93 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.27168397 |
| 94 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.27120810 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25935284 |
| 96 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.25919833 |
| 97 | Viral myocarditis_Homo sapiens_hsa05416 | 0.25778659 |
| 98 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.25558461 |
| 99 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.25264848 |
| 100 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.24028537 |

