

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | diaphragm development (GO:0060539) | 9.83758804 |
| 2 | arginine catabolic process (GO:0006527) | 9.56323847 |
| 3 | skeletal muscle organ development (GO:0060538) | 8.75930283 |
| 4 | pyrimidine nucleoside salvage (GO:0043097) | 8.18562836 |
| 5 | pyrimidine-containing compound salvage (GO:0008655) | 8.18562836 |
| 6 | cellular protein complex localization (GO:0034629) | 8.10194694 |
| 7 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 7.98609807 |
| 8 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 7.98479925 |
| 9 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 7.81858801 |
| 10 | arginine metabolic process (GO:0006525) | 7.67421034 |
| 11 | negative regulation of neurotransmitter transport (GO:0051589) | 7.63967777 |
| 12 | exogenous drug catabolic process (GO:0042738) | 7.26430759 |
| 13 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 7.08440295 |
| 14 | UMP biosynthetic process (GO:0006222) | 7.08440295 |
| 15 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 7.08440295 |
| 16 | UMP metabolic process (GO:0046049) | 7.08440295 |
| 17 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 7.03365259 |
| 18 | negative regulation of vascular permeability (GO:0043116) | 6.97383001 |
| 19 | response to lipoprotein particle (GO:0055094) | 6.89066146 |
| 20 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 6.81233742 |
| 21 | positive regulation of guanylate cyclase activity (GO:0031284) | 6.06150874 |
| 22 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 6.03695506 |
| 23 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 5.89825900 |
| 24 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 5.77251382 |
| 25 | nucleotide salvage (GO:0043173) | 5.69155206 |
| 26 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 5.66433523 |
| 27 | negative regulation of potassium ion transport (GO:0043267) | 5.63403460 |
| 28 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 5.57298077 |
| 29 | regulation of guanylate cyclase activity (GO:0031282) | 5.55386248 |
| 30 | drug catabolic process (GO:0042737) | 5.53788270 |
| 31 | nucleoside salvage (GO:0043174) | 5.46757061 |
| 32 | protein complex localization (GO:0031503) | 5.40655639 |
| 33 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 5.33992348 |
| 34 | positive regulation of receptor biosynthetic process (GO:0010870) | 5.18006735 |
| 35 | regulation of neurotransmitter uptake (GO:0051580) | 5.16194763 |
| 36 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.08863176 |
| 37 | protein heterotrimerization (GO:0070208) | 5.03278704 |
| 38 | adenine nucleotide transport (GO:0051503) | 5.03175131 |
| 39 | activation of MAPKKK activity (GO:0000185) | 5.01124901 |
| 40 | regulation of cholesterol biosynthetic process (GO:0045540) | 4.99718408 |
| 41 | histone H3-K4 methylation (GO:0051568) | 4.80817341 |
| 42 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 4.75064358 |
| 43 | regulation of mitochondrial translation (GO:0070129) | 4.66414549 |
| 44 | regulation of stem cell maintenance (GO:2000036) | 4.65778776 |
| 45 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.48874103 |
| 46 | lateral sprouting from an epithelium (GO:0060601) | 4.48398454 |
| 47 | negative regulation of protein kinase B signaling (GO:0051898) | 4.46919829 |
| 48 | mRNA stabilization (GO:0048255) | 4.44887092 |
| 49 | RNA stabilization (GO:0043489) | 4.44887092 |
| 50 | negative regulation of macrophage differentiation (GO:0045650) | 4.44059920 |
| 51 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 4.43752749 |
| 52 | nitric oxide biosynthetic process (GO:0006809) | 4.42001191 |
| 53 | negative regulation of granulocyte differentiation (GO:0030853) | 4.37057044 |
| 54 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 4.36624969 |
| 55 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 4.30044023 |
| 56 | CTP biosynthetic process (GO:0006241) | 4.25772600 |
| 57 | CTP metabolic process (GO:0046036) | 4.25772600 |
| 58 | hypotonic response (GO:0006971) | 4.23609835 |
| 59 | regulation of mRNA catabolic process (GO:0061013) | 4.21775332 |
| 60 | chromatin silencing (GO:0006342) | 4.18675876 |
| 61 | ribosomal small subunit assembly (GO:0000028) | 4.17011328 |
| 62 | nerve growth factor signaling pathway (GO:0038180) | 4.13945198 |
| 63 | regulation of intracellular estrogen receptor signaling pathway (GO:0033146) | 4.07213477 |
| 64 | negative regulation of alcohol biosynthetic process (GO:1902931) | 4.04520364 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 4.02445975 |
| 66 | purine nucleotide transport (GO:0015865) | 4.01485750 |
| 67 | purine ribonucleotide transport (GO:0015868) | 3.97809786 |
| 68 | regulation of protein deacetylation (GO:0090311) | 3.96040098 |
| 69 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.92822851 |
| 70 | urea cycle (GO:0000050) | 3.89197226 |
| 71 | positive regulation of mRNA catabolic process (GO:0061014) | 3.83983208 |
| 72 | myoblast fusion (GO:0007520) | 3.83787495 |
| 73 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 3.82611428 |
| 74 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.79009109 |
| 75 | neurotransmitter biosynthetic process (GO:0042136) | 3.78706004 |
| 76 | positive regulation of catecholamine secretion (GO:0033605) | 3.77176690 |
| 77 | ncRNA 3-end processing (GO:0043628) | 3.75271608 |
| 78 | nitric oxide mediated signal transduction (GO:0007263) | 3.69626660 |
| 79 | regulation of cilium assembly (GO:1902017) | 3.69592644 |
| 80 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.69022966 |
| 81 | regulation of oxidative phosphorylation (GO:0002082) | 3.68273036 |
| 82 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.64437589 |
| 83 | urea metabolic process (GO:0019627) | 3.60936719 |
| 84 | positive regulation of cGMP biosynthetic process (GO:0030828) | 3.60073864 |
| 85 | inactivation of MAPK activity (GO:0000188) | 3.55293936 |
| 86 | positive regulation of histone acetylation (GO:0035066) | 3.54890386 |
| 87 | oogenesis (GO:0048477) | 3.53417884 |
| 88 | regulation of cell size (GO:0008361) | 3.49044725 |
| 89 | peptidyl-cysteine modification (GO:0018198) | 3.48064983 |
| 90 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.45473056 |
| 91 | regulation of cGMP biosynthetic process (GO:0030826) | 3.40963416 |
| 92 | syncytium formation by plasma membrane fusion (GO:0000768) | 3.40223842 |
| 93 | Rap protein signal transduction (GO:0032486) | 3.32891619 |
| 94 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.29569203 |
| 95 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 3.26612427 |
| 96 | regulation of synaptic vesicle transport (GO:1902803) | 3.26171962 |
| 97 | cellular response to nerve growth factor stimulus (GO:1990090) | 3.25407990 |
| 98 | response to nerve growth factor (GO:1990089) | 3.25407990 |
| 99 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 3.24362181 |
| 100 | positive regulation of cell size (GO:0045793) | 11.0189984 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 6.73623854 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.20370560 |
| 3 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.90789031 |
| 4 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 2.95159582 |
| 5 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 2.94322571 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.53428298 |
| 7 | GATA1_22025678_ChIP-Seq_K562_Human | 2.41192626 |
| 8 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.36375633 |
| 9 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.12856636 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.08897997 |
| 11 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 2.02076530 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 12.7701648 |
| 13 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.96183988 |
| 14 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.87024994 |
| 15 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.86007598 |
| 16 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.79034193 |
| 17 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.70009258 |
| 18 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.64806268 |
| 19 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.62188897 |
| 20 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.59683019 |
| 21 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.57400197 |
| 22 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.55268026 |
| 23 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.48240599 |
| 24 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.46163014 |
| 25 | KDM2B_26808549_Chip-Seq_K562_Human | 1.42574112 |
| 26 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.34769363 |
| 27 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.34517340 |
| 28 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.32650293 |
| 29 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.32406887 |
| 30 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.24387799 |
| 31 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.22921465 |
| 32 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.21315902 |
| 33 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.17718929 |
| 34 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.17108414 |
| 35 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.15987334 |
| 36 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.13395509 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.08723083 |
| 38 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.07580862 |
| 39 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.04912292 |
| 40 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.03614679 |
| 41 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.03475833 |
| 42 | SMAD4_21741376_ChIP-Seq_ESCs_Human | 1.03358967 |
| 43 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00416784 |
| 44 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.99824862 |
| 45 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.99240842 |
| 46 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.99033236 |
| 47 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.97202060 |
| 48 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.95029673 |
| 49 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.94300715 |
| 50 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.91639973 |
| 51 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.91562051 |
| 52 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.91545857 |
| 53 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.91232989 |
| 54 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.90508704 |
| 55 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.90121175 |
| 56 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.89451388 |
| 57 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.88909993 |
| 58 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.86229799 |
| 59 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.85814156 |
| 60 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.85206223 |
| 61 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.84876586 |
| 62 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.84873671 |
| 63 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.84873671 |
| 64 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.81024877 |
| 65 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.80862335 |
| 66 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.79957939 |
| 67 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.79422666 |
| 68 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.77688077 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.77449252 |
| 70 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.77305874 |
| 71 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.77296968 |
| 72 | ERA_21632823_ChIP-Seq_H3396_Human | 0.76746847 |
| 73 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.76525016 |
| 74 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75935769 |
| 75 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.75714989 |
| 76 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.75062333 |
| 77 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.74576151 |
| 78 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.73201493 |
| 79 | GATA3_26560356_Chip-Seq_TH2_Human | 0.72469217 |
| 80 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.72469213 |
| 81 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.72300848 |
| 82 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.71654902 |
| 83 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.71608449 |
| 84 | PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 0.71602921 |
| 85 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.70702386 |
| 86 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70318657 |
| 87 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.70207525 |
| 88 | P68_20966046_ChIP-Seq_HELA_Human | 0.70196782 |
| 89 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.70192573 |
| 90 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.69685351 |
| 91 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.69518243 |
| 92 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.69082630 |
| 93 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.69054796 |
| 94 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.68075281 |
| 95 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.67935984 |
| 96 | GATA1_19941826_ChIP-Seq_K562_Human | 0.67796247 |
| 97 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.67731142 |
| 98 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.66655754 |
| 99 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.65887283 |
| 100 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.65693821 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 8.20913786 |
| 2 | MP0003646_muscle_fatigue | 7.89704440 |
| 3 | MP0002234_abnormal_pharynx_morphology | 5.62857467 |
| 4 | MP0004233_abnormal_muscle_weight | 4.76992546 |
| 5 | MP0004858_abnormal_nervous_system | 4.76286503 |
| 6 | MP0010368_abnormal_lymphatic_system | 4.50753436 |
| 7 | MP0004043_abnormal_pH_regulation | 4.34578099 |
| 8 | MP0005167_abnormal_blood-brain_barrier | 4.06806117 |
| 9 | MP0005645_abnormal_hypothalamus_physiol | 4.01016135 |
| 10 | MP0009053_abnormal_anal_canal | 3.21219408 |
| 11 | MP0006082_CNS_inflammation | 2.97874249 |
| 12 | MP0003283_abnormal_digestive_organ | 2.66822895 |
| 13 | MP0004084_abnormal_cardiac_muscle | 2.58184986 |
| 14 | MP0003045_fibrosis | 2.45412195 |
| 15 | MP0000467_abnormal_esophagus_morphology | 2.10014623 |
| 16 | MP0002009_preneoplasia | 1.97565666 |
| 17 | MP0003718_maternal_effect | 1.91488044 |
| 18 | MP0005076_abnormal_cell_differentiation | 1.77344727 |
| 19 | MP0001919_abnormal_reproductive_system | 1.77142208 |
| 20 | MP0010307_abnormal_tumor_latency | 1.70510804 |
| 21 | MP0002233_abnormal_nose_morphology | 1.61535244 |
| 22 | MP0000733_abnormal_muscle_development | 1.60063936 |
| 23 | MP0001664_abnormal_digestion | 1.59462000 |
| 24 | MP0000537_abnormal_urethra_morphology | 1.47753863 |
| 25 | MP0001501_abnormal_sleep_pattern | 1.46326425 |
| 26 | MP0008872_abnormal_physiological_respon | 1.40248726 |
| 27 | MP0004036_abnormal_muscle_relaxation | 1.36712020 |
| 28 | MP0006138_congestive_heart_failure | 1.29123920 |
| 29 | MP0001879_abnormal_lymphatic_vessel | 1.22014133 |
| 30 | MP0000767_abnormal_smooth_muscle | 1.20490639 |
| 31 | MP0000470_abnormal_stomach_morphology | 1.18709500 |
| 32 | MP0004484_altered_response_of | 1.18441864 |
| 33 | MP0008775_abnormal_heart_ventricle | 1.17108886 |
| 34 | MP0004883_abnormal_blood_vessel | 1.07779348 |
| 35 | MP0002127_abnormal_cardiovascular_syste | 1.06606950 |
| 36 | MP0001764_abnormal_homeostasis | 1.02255829 |
| 37 | MP0005197_abnormal_uvea_morphology | 1.02065206 |
| 38 | MP0009764_decreased_sensitivity_to | 0.96181975 |
| 39 | MP0002109_abnormal_limb_morphology | 0.95194341 |
| 40 | MP0000383_abnormal_hair_follicle | 0.95101166 |
| 41 | MP0003937_abnormal_limbs/digits/tail_de | 0.93948539 |
| 42 | MP0001440_abnormal_grooming_behavior | 0.90564877 |
| 43 | MP0002116_abnormal_craniofacial_bone | 0.86947286 |
| 44 | MP0000490_abnormal_crypts_of | 0.86035297 |
| 45 | MP0000432_abnormal_head_morphology | 0.80290694 |
| 46 | MP0003075_altered_response_to | 0.78777015 |
| 47 | MP0005389_reproductive_system_phenotype | 0.77323744 |
| 48 | MP0005499_abnormal_olfactory_system | 0.74920983 |
| 49 | MP0005394_taste/olfaction_phenotype | 0.74920983 |
| 50 | MP0003123_paternal_imprinting | 0.73319059 |
| 51 | MP0002113_abnormal_skeleton_development | 0.72526601 |
| 52 | MP0004133_heterotaxia | 0.70686028 |
| 53 | MP0000163_abnormal_cartilage_morphology | 0.68187679 |
| 54 | MP0002396_abnormal_hematopoietic_system | 0.66819587 |
| 55 | MP0000955_abnormal_spinal_cord | 0.64127916 |
| 56 | MP0005166_decreased_susceptibility_to | 0.61676422 |
| 57 | MP0000631_abnormal_neuroendocrine_gland | 0.59039802 |
| 58 | MP0001756_abnormal_urination | 0.57698517 |
| 59 | MP0002168_other_aberrant_phenotype | 0.57690530 |
| 60 | MP0003633_abnormal_nervous_system | 0.57689586 |
| 61 | MP0000858_altered_metastatic_potential | 0.55809260 |
| 62 | MP0008058_abnormal_DNA_repair | 0.54981595 |
| 63 | MP0010329_abnormal_lipoprotein_level | 0.54711207 |
| 64 | MP0010678_abnormal_skin_adnexa | 0.54340789 |
| 65 | MP0005058_abnormal_lysosome_morphology | 0.53794069 |
| 66 | MP0003763_abnormal_thymus_physiology | 0.53314209 |
| 67 | MP0000477_abnormal_intestine_morphology | 0.52327823 |
| 68 | MP0003631_nervous_system_phenotype | 0.51980155 |
| 69 | MP0000428_abnormal_craniofacial_morphol | 0.50213621 |
| 70 | MP0001663_abnormal_digestive_system | 0.49579569 |
| 71 | MP0003942_abnormal_urinary_system | 0.45895229 |
| 72 | MP0008789_abnormal_olfactory_epithelium | 0.44884524 |
| 73 | MP0005332_abnormal_amino_acid | 0.44771006 |
| 74 | MP0004811_abnormal_neuron_physiology | 0.44519442 |
| 75 | MP0002115_abnormal_skeleton_extremities | 0.43055177 |
| 76 | MP0003315_abnormal_perineum_morphology | 0.42566142 |
| 77 | MP0001119_abnormal_female_reproductive | 0.40615925 |
| 78 | MP0009672_abnormal_birth_weight | 0.40328871 |
| 79 | MP0002932_abnormal_joint_morphology | 0.39355405 |
| 80 | MP0009745_abnormal_behavioral_response | 0.36978320 |
| 81 | MP0001784_abnormal_fluid_regulation | 0.35714997 |
| 82 | MP0005164_abnormal_response_to | 0.35425915 |
| 83 | MP0008260_abnormal_autophagy | 0.34931777 |
| 84 | MP0005367_renal/urinary_system_phenotyp | 0.34683764 |
| 85 | MP0000516_abnormal_urinary_system | 0.34683764 |
| 86 | MP0003119_abnormal_digestive_system | 0.34654755 |
| 87 | MP0003828_pulmonary_edema | 0.33800203 |
| 88 | MP0008874_decreased_physiological_sensi | 0.31250037 |
| 89 | MP0005395_other_phenotype | 0.30727379 |
| 90 | MP0002084_abnormal_developmental_patter | 0.30522932 |
| 91 | MP0003566_abnormal_cell_adhesion | 0.29548630 |
| 92 | MP0002064_seizures | 0.27540203 |
| 93 | MP0000538_abnormal_urinary_bladder | 0.26911249 |
| 94 | MP0002063_abnormal_learning/memory/cond | 0.26170976 |
| 95 | MP0001873_stomach_inflammation | 0.25717155 |
| 96 | MP0005670_abnormal_white_adipose | 0.25271265 |
| 97 | MP0003448_altered_tumor_morphology | 0.25100950 |
| 98 | MP0002132_abnormal_respiratory_system | 0.24858857 |
| 99 | MP0002272_abnormal_nervous_system | 0.24420739 |
| 100 | MP0002184_abnormal_innervation | 0.24394077 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Lip pit (HP:0100267) | 8.89412008 |
| 2 | Autoimmune thrombocytopenia (HP:0001973) | 8.82719930 |
| 3 | Sparse lateral eyebrow (HP:0005338) | 8.42943802 |
| 4 | Anal stenosis (HP:0002025) | 7.86275597 |
| 5 | Depressed nasal tip (HP:0000437) | 6.95449200 |
| 6 | Intestinal fistula (HP:0100819) | 6.77596177 |
| 7 | Abnormality of the fingertips (HP:0001211) | 6.65959007 |
| 8 | Ureteral stenosis (HP:0000071) | 6.05702714 |
| 9 | Short 5th finger (HP:0009237) | 5.79351743 |
| 10 | Ureteral obstruction (HP:0006000) | 5.57403428 |
| 11 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 5.39792065 |
| 12 | Popliteal pterygium (HP:0009756) | 4.87335495 |
| 13 | Lower limb hyperreflexia (HP:0002395) | 4.85160590 |
| 14 | Ectopic kidney (HP:0000086) | 4.18159534 |
| 15 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 4.12710509 |
| 16 | Vertebral hypoplasia (HP:0008417) | 4.12710509 |
| 17 | Mucopolysacchariduria (HP:0008155) | 4.00048633 |
| 18 | Urinary glycosaminoglycan excretion (HP:0003541) | 4.00048633 |
| 19 | Preauricular pit (HP:0004467) | 3.76329377 |
| 20 | Periauricular skin pits (HP:0100277) | 3.76329377 |
| 21 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.73706728 |
| 22 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.73706728 |
| 23 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.73706728 |
| 24 | Long palpebral fissure (HP:0000637) | 3.73288557 |
| 25 | Posterior subcapsular cataract (HP:0007787) | 3.72138178 |
| 26 | Increased CSF protein (HP:0002922) | 3.52850892 |
| 27 | Dysostosis multiplex (HP:0000943) | 3.47281311 |
| 28 | Ectropion (HP:0000656) | 3.46587949 |
| 29 | Natal tooth (HP:0000695) | 3.17430956 |
| 30 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.94865339 |
| 31 | Abnormality of the periventricular white matter (HP:0002518) | 2.90706413 |
| 32 | Facial cleft (HP:0002006) | 2.87368661 |
| 33 | Absent eyebrow (HP:0002223) | 2.87099598 |
| 34 | Self-mutilation (HP:0000742) | 2.86741983 |
| 35 | Mask-like facies (HP:0000298) | 2.86334820 |
| 36 | Pheochromocytoma (HP:0002666) | 2.84046594 |
| 37 | Neonatal short-limb short stature (HP:0008921) | 2.77313589 |
| 38 | Wide intermamillary distance (HP:0006610) | 2.66695616 |
| 39 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.66421483 |
| 40 | Absent eyelashes (HP:0000561) | 2.66036547 |
| 41 | Broad thumb (HP:0011304) | 2.61730167 |
| 42 | Narrow palate (HP:0000189) | 2.55662888 |
| 43 | Fibular aplasia (HP:0002990) | 2.52005533 |
| 44 | Preaxial foot polydactyly (HP:0001841) | 2.51915382 |
| 45 | Recurrent otitis media (HP:0000403) | 2.51673384 |
| 46 | Congenital hip dislocation (HP:0001374) | 2.51124943 |
| 47 | Leiomyosarcoma (HP:0100243) | 2.49008733 |
| 48 | Uterine leiomyosarcoma (HP:0002891) | 2.49008733 |
| 49 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.46450177 |
| 50 | Aplasia of the phalanges of the hand (HP:0009802) | 2.46450177 |
| 51 | Aplasia involving bones of the extremities (HP:0009825) | 2.46450177 |
| 52 | Pterygium (HP:0001059) | 2.41327790 |
| 53 | Non-midline cleft lip (HP:0100335) | 2.41030991 |
| 54 | Progressive neurologic deterioration (HP:0002344) | 2.40802607 |
| 55 | Neuroendocrine neoplasm (HP:0100634) | 2.40255563 |
| 56 | Skin pits (HP:0100276) | 2.40207174 |
| 57 | Coarctation of aorta (HP:0001680) | 2.38974178 |
| 58 | Renal cell carcinoma (HP:0005584) | 2.38921230 |
| 59 | Broad hallux (HP:0010055) | 2.35908449 |
| 60 | Neonatal death (HP:0003811) | 2.33997251 |
| 61 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.31848760 |
| 62 | Trismus (HP:0000211) | 2.31311149 |
| 63 | Atonic seizures (HP:0010819) | 2.30467597 |
| 64 | Generalized aminoaciduria (HP:0002909) | 2.27611113 |
| 65 | Fatigue (HP:0012378) | 2.22719052 |
| 66 | Anal atresia (HP:0002023) | 2.20266077 |
| 67 | Frequent falls (HP:0002359) | 2.18517539 |
| 68 | Hypoplastic labia majora (HP:0000059) | 2.17260258 |
| 69 | Transitional cell carcinoma of the bladder (HP:0006740) | 2.15754676 |
| 70 | Confusion (HP:0001289) | 2.13641178 |
| 71 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 2.08832478 |
| 72 | Facial shape deformation (HP:0011334) | 2.06767799 |
| 73 | Potter facies (HP:0002009) | 2.06767799 |
| 74 | Asymmetry of the thorax (HP:0001555) | 2.06008668 |
| 75 | Tubulointerstitial fibrosis (HP:0005576) | 2.05571972 |
| 76 | Subcapsular cataract (HP:0000523) | 2.02862612 |
| 77 | Abnormality of the labia majora (HP:0012881) | 2.01445427 |
| 78 | Abnormality of the renal cortex (HP:0011035) | 2.01418838 |
| 79 | Abnormality of cochlea (HP:0000375) | 1.98571761 |
| 80 | Blue irides (HP:0000635) | 1.96711216 |
| 81 | Poor head control (HP:0002421) | 1.96636142 |
| 82 | Obstructive sleep apnea (HP:0002870) | 1.95554988 |
| 83 | Tubular atrophy (HP:0000092) | 1.93987831 |
| 84 | Bladder carcinoma (HP:0002862) | 1.91728404 |
| 85 | Bladder neoplasm (HP:0009725) | 1.91728404 |
| 86 | Flat face (HP:0012368) | 1.90051744 |
| 87 | Polydipsia (HP:0001959) | 1.88888672 |
| 88 | Abnormal drinking behavior (HP:0030082) | 1.88888672 |
| 89 | Broad phalanges of the hand (HP:0009768) | 1.88521064 |
| 90 | Broad toe (HP:0001837) | 1.88274528 |
| 91 | Abnormal number of incisors (HP:0011064) | 1.86154659 |
| 92 | Absent thumb (HP:0009777) | 1.84968548 |
| 93 | Concave nail (HP:0001598) | 1.81131298 |
| 94 | Chronic bronchitis (HP:0004469) | 1.80903396 |
| 95 | Conical tooth (HP:0000698) | 1.80148095 |
| 96 | Spontaneous abortion (HP:0005268) | 1.75997325 |
| 97 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.73623008 |
| 98 | Absent hand (HP:0004050) | 1.73548751 |
| 99 | Broad finger (HP:0001500) | 1.73034905 |
| 100 | Advanced eruption of teeth (HP:0006288) | 1.72997300 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK24 | 8.81011583 |
| 2 | STK39 | 5.50293465 |
| 3 | WNK4 | 5.49044614 |
| 4 | CCNB1 | 4.74934577 |
| 5 | PINK1 | 4.17901368 |
| 6 | MAP3K2 | 4.07724428 |
| 7 | MAP3K3 | 3.95868117 |
| 8 | EEF2K | 3.80447839 |
| 9 | JAK3 | 2.94209388 |
| 10 | ILK | 2.42428262 |
| 11 | MAPKAPK3 | 2.26355830 |
| 12 | WNK1 | 2.11878406 |
| 13 | ZAK | 2.07019085 |
| 14 | CAMK4 | 1.57528850 |
| 15 | CAMK1 | 1.57173628 |
| 16 | RPS6KL1 | 1.38681811 |
| 17 | RPS6KC1 | 1.38681811 |
| 18 | CHEK2 | 1.38291046 |
| 19 | RPS6KA6 | 1.34133210 |
| 20 | PRKCQ | 1.30394965 |
| 21 | TRPM7 | 1.27903815 |
| 22 | NTRK2 | 1.25020442 |
| 23 | CDC7 | 1.15441900 |
| 24 | SRPK1 | 0.98366969 |
| 25 | MAPKAPK5 | 0.95439174 |
| 26 | CAMK1G | 0.93252395 |
| 27 | RPS6KB2 | 0.92510299 |
| 28 | MINK1 | 0.76258417 |
| 29 | CAMKK2 | 0.75668959 |
| 30 | TTK | 0.75609047 |
| 31 | RPS6KA2 | 0.70511093 |
| 32 | CAMK1D | 0.66977101 |
| 33 | DAPK2 | 0.66863751 |
| 34 | CDK9 | 0.57778139 |
| 35 | NEK9 | 0.56326284 |
| 36 | PNCK | 0.54414625 |
| 37 | TNIK | 0.51627257 |
| 38 | ACVR1B | 0.48098636 |
| 39 | STK4 | 0.45491396 |
| 40 | IRAK3 | 0.44864743 |
| 41 | MAPK13 | 0.43442684 |
| 42 | CAMKK1 | 0.42170207 |
| 43 | PASK | 0.38217563 |
| 44 | TNK2 | 0.35006036 |
| 45 | DYRK3 | 0.32494300 |
| 46 | HCK | 0.31314758 |
| 47 | YES1 | 0.29488910 |
| 48 | EGFR | 0.27724037 |
| 49 | MELK | 0.27697047 |
| 50 | PRPF4B | 0.27553139 |
| 51 | EIF2AK2 | 0.27478482 |
| 52 | MAP3K10 | 0.26757947 |
| 53 | BCKDK | 0.26134533 |
| 54 | GRK1 | 0.22262582 |
| 55 | CSNK1G3 | 0.21614769 |
| 56 | WEE1 | 0.17412075 |
| 57 | RPS6KB1 | 0.16478977 |
| 58 | ADRBK1 | 0.16276304 |
| 59 | JAK1 | 0.15405325 |
| 60 | SGK2 | 0.15221058 |
| 61 | PRKCD | 0.15005648 |
| 62 | MAPK12 | 0.14931607 |
| 63 | CSNK1A1L | 0.13698240 |
| 64 | PRKCZ | 0.13598284 |
| 65 | PRKCG | 0.11924684 |
| 66 | PRKACG | 0.11423101 |
| 67 | MAPK11 | 0.10786600 |
| 68 | MAPK9 | 0.10689501 |
| 69 | MTOR | 0.09983058 |
| 70 | CSNK1G2 | 0.09633303 |
| 71 | BMPR1B | 0.09608380 |
| 72 | MAP3K5 | 0.09225485 |
| 73 | PRKG2 | 0.09082462 |
| 74 | CSNK1G1 | 0.07408232 |
| 75 | PRKCA | 0.06834312 |
| 76 | KIT | 0.06765493 |
| 77 | ERBB3 | 0.04847357 |
| 78 | IRAK2 | 0.03626266 |
| 79 | PIM1 | 0.03540902 |
| 80 | MAP3K11 | 0.03026273 |
| 81 | CAMK2A | 0.02474816 |
| 82 | BMX | 0.02122038 |
| 83 | FER | 0.02010282 |
| 84 | SGK494 | 0.00993595 |
| 85 | SGK223 | 0.00993595 |
| 86 | PRKACA | 0.00235464 |
| 87 | PRKCE | 0.00020914 |
| 88 | RPS6KA1 | -0.0625200 |
| 89 | OBSCN | -0.0619123 |
| 90 | SGK3 | -0.0522405 |
| 91 | ABL1 | -0.0490454 |
| 92 | MAP2K1 | -0.0478961 |
| 93 | ROCK1 | -0.0465281 |
| 94 | ERBB2 | -0.0312891 |
| 95 | SRC | -0.0284970 |
| 96 | TXK | -0.0248936 |
| 97 | MAP4K2 | -0.0211135 |
| 98 | IRAK4 | -0.0208145 |
| 99 | INSR | -0.0151115 |
| 100 | CDK2 | -0.0117776 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Arginine biosynthesis_Homo sapiens_hsa00220 | 8.93947633 |
| 2 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 4.20725488 |
| 3 | Lysine degradation_Homo sapiens_hsa00310 | 3.84426306 |
| 4 | AMPK signaling pathway_Homo sapiens_hsa04152 | 3.33863970 |
| 5 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 2.52467940 |
| 6 | Phototransduction_Homo sapiens_hsa04744 | 2.46039215 |
| 7 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 2.14770079 |
| 8 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.09911348 |
| 9 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.07329339 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.82604596 |
| 11 | Circadian entrainment_Homo sapiens_hsa04713 | 1.81141068 |
| 12 | Salivary secretion_Homo sapiens_hsa04970 | 1.72250439 |
| 13 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.65101106 |
| 14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.63649049 |
| 15 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.62069112 |
| 16 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.53759254 |
| 17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.51169295 |
| 18 | Long-term depression_Homo sapiens_hsa04730 | 1.44794169 |
| 19 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.44476389 |
| 20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.43476345 |
| 21 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 1.41201335 |
| 22 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.38920058 |
| 23 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.37035027 |
| 24 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.33148448 |
| 25 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.27573528 |
| 26 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.18693058 |
| 27 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.18669215 |
| 28 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.15805582 |
| 29 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.12903601 |
| 30 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.11514867 |
| 31 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.11162132 |
| 32 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.07900591 |
| 33 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.04666199 |
| 34 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.95261774 |
| 35 | Taste transduction_Homo sapiens_hsa04742 | 0.94573901 |
| 36 | Pertussis_Homo sapiens_hsa05133 | 0.91156872 |
| 37 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.85550243 |
| 38 | Adherens junction_Homo sapiens_hsa04520 | 0.84346995 |
| 39 | Phagosome_Homo sapiens_hsa04145 | 0.82537111 |
| 40 | Olfactory transduction_Homo sapiens_hsa04740 | 0.81317823 |
| 41 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.78440106 |
| 42 | Endocytosis_Homo sapiens_hsa04144 | 0.76660377 |
| 43 | Other glycan degradation_Homo sapiens_hsa00511 | 0.74485864 |
| 44 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.73877154 |
| 45 | Glioma_Homo sapiens_hsa05214 | 0.71813279 |
| 46 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67591671 |
| 47 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.65714106 |
| 48 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.62140893 |
| 49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.61311357 |
| 50 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.57309931 |
| 51 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.56807617 |
| 52 | Renin secretion_Homo sapiens_hsa04924 | 0.56081192 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.54546857 |
| 54 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.53877374 |
| 55 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.52416250 |
| 56 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.50237424 |
| 57 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.49778331 |
| 58 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.49050856 |
| 59 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.48995458 |
| 60 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.44780864 |
| 61 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.41026064 |
| 62 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40383245 |
| 63 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.39062187 |
| 64 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.38875928 |
| 65 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.38638358 |
| 66 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.37208984 |
| 67 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.37051071 |
| 68 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.35641113 |
| 69 | Alcoholism_Homo sapiens_hsa05034 | 0.31442272 |
| 70 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.31272806 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.30511921 |
| 72 | Measles_Homo sapiens_hsa05162 | 0.29106941 |
| 73 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.28547001 |
| 74 | Lysosome_Homo sapiens_hsa04142 | 0.25835146 |
| 75 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.24518148 |
| 76 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.23136252 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.22608194 |
| 78 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.22554939 |
| 79 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.21393829 |
| 80 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.20631143 |
| 81 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.20289001 |
| 82 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.20131798 |
| 83 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.19476879 |
| 84 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.19381605 |
| 85 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.18385435 |
| 86 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.17100046 |
| 87 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.16841484 |
| 88 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.16837307 |
| 89 | Long-term potentiation_Homo sapiens_hsa04720 | 0.15741485 |
| 90 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.15449488 |
| 91 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.15169147 |
| 92 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.14257503 |
| 93 | Melanogenesis_Homo sapiens_hsa04916 | 0.13345050 |
| 94 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.13043550 |
| 95 | Focal adhesion_Homo sapiens_hsa04510 | 0.12453004 |
| 96 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.12084039 |
| 97 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.11035023 |
| 98 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.10989100 |
| 99 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.10239325 |
| 100 | Peroxisome_Homo sapiens_hsa04146 | 0.10098282 |

