

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 9.92042925 |
| 2 | tachykinin receptor signaling pathway (GO:0007217) | 8.51856882 |
| 3 | regulation of uterine smooth muscle contraction (GO:0070472) | 8.02544734 |
| 4 | positive regulation of protein homodimerization activity (GO:0090073) | 7.14131050 |
| 5 | regulation of mitochondrial translation (GO:0070129) | 5.92109577 |
| 6 | viral transcription (GO:0019083) | 5.78862582 |
| 7 | translational termination (GO:0006415) | 5.53730966 |
| 8 | regulation of feeding behavior (GO:0060259) | 5.10529016 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.81815438 |
| 10 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.80475477 |
| 11 | cotranslational protein targeting to membrane (GO:0006613) | 4.72820098 |
| 12 | translational elongation (GO:0006414) | 4.70181950 |
| 13 | protein targeting to ER (GO:0045047) | 4.68005408 |
| 14 | positive regulation of T cell cytokine production (GO:0002726) | 4.59142731 |
| 15 | mitochondrial calcium ion transport (GO:0006851) | 4.58123092 |
| 16 | ribosomal small subunit biogenesis (GO:0042274) | 4.50882309 |
| 17 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.46919871 |
| 18 | positive regulation of smooth muscle contraction (GO:0045987) | 4.44131402 |
| 19 | cellular response to nitric oxide (GO:0071732) | 4.43248524 |
| 20 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.42649931 |
| 21 | protein localization to endoplasmic reticulum (GO:0070972) | 4.42288220 |
| 22 | cellular protein complex disassembly (GO:0043624) | 4.42272164 |
| 23 | chaperone-mediated protein transport (GO:0072321) | 4.38827870 |
| 24 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.22173451 |
| 25 | viral life cycle (GO:0019058) | 4.15699304 |
| 26 | purine deoxyribonucleotide catabolic process (GO:0009155) | 4.12761738 |
| 27 | translational initiation (GO:0006413) | 4.07903590 |
| 28 | NIK/NF-kappaB signaling (GO:0038061) | 4.04132136 |
| 29 | response to pheromone (GO:0019236) | 4.01420981 |
| 30 | grooming behavior (GO:0007625) | 3.86794809 |
| 31 | maturation of SSU-rRNA (GO:0030490) | 3.85282673 |
| 32 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.82733466 |
| 33 | ATP synthesis coupled proton transport (GO:0015986) | 3.82733466 |
| 34 | purine nucleotide salvage (GO:0032261) | 3.82001042 |
| 35 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.79154315 |
| 36 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.77661770 |
| 37 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.74673111 |
| 38 | ncRNA 3-end processing (GO:0043628) | 3.68541205 |
| 39 | positive regulation of growth hormone secretion (GO:0060124) | 3.64777540 |
| 40 | proteasome assembly (GO:0043248) | 3.63435026 |
| 41 | ribosomal small subunit assembly (GO:0000028) | 3.60856302 |
| 42 | protein complex disassembly (GO:0043241) | 3.56864171 |
| 43 | deoxyribose phosphate catabolic process (GO:0046386) | 3.55408325 |
| 44 | ubiquinone biosynthetic process (GO:0006744) | 3.52058240 |
| 45 | ribosomal large subunit biogenesis (GO:0042273) | 3.49922370 |
| 46 | macromolecular complex disassembly (GO:0032984) | 3.44584359 |
| 47 | positive regulation of muscle contraction (GO:0045933) | 3.42567784 |
| 48 | hyperosmotic salinity response (GO:0042538) | 3.38071108 |
| 49 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.37413643 |
| 50 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.36423391 |
| 51 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35069519 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35069519 |
| 53 | protein homotrimerization (GO:0070207) | 3.31524278 |
| 54 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.31403917 |
| 55 | pantothenate metabolic process (GO:0015939) | 3.29482652 |
| 56 | regulation of oxidative phosphorylation (GO:0002082) | 3.28323759 |
| 57 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.23436311 |
| 58 | regulation of gonadotropin secretion (GO:0032276) | 3.23118409 |
| 59 | protein targeting to membrane (GO:0006612) | 3.22474601 |
| 60 | translation (GO:0006412) | 3.18530506 |
| 61 | negative regulation of telomere maintenance (GO:0032205) | 3.16125031 |
| 62 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.14231607 |
| 63 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.13953259 |
| 64 | regulation of immunoglobulin secretion (GO:0051023) | 3.13756069 |
| 65 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.11052773 |
| 66 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.10807973 |
| 67 | ubiquinone metabolic process (GO:0006743) | 3.10489280 |
| 68 | response to nitric oxide (GO:0071731) | 3.08734799 |
| 69 | electron transport chain (GO:0022900) | 3.04597145 |
| 70 | respiratory electron transport chain (GO:0022904) | 3.03468155 |
| 71 | positive regulation of heart rate (GO:0010460) | 3.02760308 |
| 72 | formation of translation preinitiation complex (GO:0001731) | 3.01774576 |
| 73 | DNA deamination (GO:0045006) | 3.01384242 |
| 74 | peptidyl-arginine N-methylation (GO:0035246) | 3.01191509 |
| 75 | peptidyl-arginine methylation (GO:0018216) | 3.01191509 |
| 76 | actin nucleation (GO:0045010) | 2.99491675 |
| 77 | regulation of protein homodimerization activity (GO:0043496) | 2.96442197 |
| 78 | regulation of dopamine metabolic process (GO:0042053) | 2.94412356 |
| 79 | regulation of catecholamine metabolic process (GO:0042069) | 2.94412356 |
| 80 | DNA damage response, detection of DNA damage (GO:0042769) | 2.93327718 |
| 81 | histone arginine methylation (GO:0034969) | 2.91872723 |
| 82 | regulation of translational termination (GO:0006449) | 2.90588687 |
| 83 | quinone biosynthetic process (GO:1901663) | 2.90346684 |
| 84 | coenzyme A biosynthetic process (GO:0015937) | 2.90002578 |
| 85 | deoxyribonucleotide catabolic process (GO:0009264) | 2.85063155 |
| 86 | positive regulation of blood pressure (GO:0045777) | 2.84854758 |
| 87 | hepatocyte apoptotic process (GO:0097284) | 2.84777598 |
| 88 | regulation of T cell cytokine production (GO:0002724) | 2.84665069 |
| 89 | protein refolding (GO:0042026) | 2.82709253 |
| 90 | coenzyme A metabolic process (GO:0015936) | 2.82466235 |
| 91 | artery smooth muscle contraction (GO:0014824) | 2.78285760 |
| 92 | regulation of cellular amine metabolic process (GO:0033238) | 2.78254725 |
| 93 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.73999295 |
| 94 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.73190276 |
| 95 | metallo-sulfur cluster assembly (GO:0031163) | 2.71637947 |
| 96 | iron-sulfur cluster assembly (GO:0016226) | 2.71637947 |
| 97 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.69310093 |
| 98 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.69187024 |
| 99 | rRNA transcription (GO:0009303) | 2.68015076 |
| 100 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.67491104 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 7.10620266 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.14060594 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.88030059 |
| 4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.26169381 |
| 5 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.13587577 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.96482270 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.82851380 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.72537396 |
| 9 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.71345095 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.70926835 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.49050440 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.33288992 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.27976206 |
| 14 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 2.22174913 |
| 15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.04257031 |
| 16 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.00514635 |
| 17 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.95015766 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 1.92569490 |
| 19 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.90573952 |
| 20 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.85666524 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.82976115 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.82936838 |
| 23 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.81633018 |
| 24 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75504106 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.72775004 |
| 26 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.69475771 |
| 27 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.59641665 |
| 28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.58823089 |
| 29 | ERA_21632823_ChIP-Seq_H3396_Human | 1.58135237 |
| 30 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.57031267 |
| 31 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.56862228 |
| 32 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.52226860 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.51281838 |
| 34 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.40958625 |
| 35 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.35960675 |
| 36 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.35456734 |
| 37 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31768641 |
| 38 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30534674 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.30102295 |
| 40 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.26129225 |
| 41 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.25690681 |
| 42 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.24349535 |
| 43 | SA1_27219007_Chip-Seq_Bcells_Human | 1.22922605 |
| 44 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.22682658 |
| 45 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.18732822 |
| 46 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.17317660 |
| 47 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.17247881 |
| 48 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.16792668 |
| 49 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.16659128 |
| 50 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.15494577 |
| 51 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.13820403 |
| 52 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.13581873 |
| 53 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.12709956 |
| 54 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.12324866 |
| 55 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12220170 |
| 56 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.11860296 |
| 57 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.11660042 |
| 58 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11446868 |
| 59 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.10481708 |
| 60 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.10168667 |
| 61 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.06591935 |
| 62 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.05464399 |
| 63 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05126385 |
| 64 | P68_20966046_ChIP-Seq_HELA_Human | 1.05005115 |
| 65 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.03281594 |
| 66 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.03035727 |
| 67 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.00458640 |
| 68 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00371830 |
| 69 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.00369675 |
| 70 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.00152933 |
| 71 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98954370 |
| 72 | GATA3_26560356_Chip-Seq_TH2_Human | 0.98700758 |
| 73 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.98334921 |
| 74 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97835156 |
| 75 | P300_27268052_Chip-Seq_Bcells_Human | 0.97822058 |
| 76 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.97130039 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94829802 |
| 78 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.94522763 |
| 79 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.93892042 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93210544 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93210544 |
| 82 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.93166983 |
| 83 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.92803483 |
| 84 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92344175 |
| 85 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.91979707 |
| 86 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.91750452 |
| 87 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.88935578 |
| 88 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.88723802 |
| 89 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.86755168 |
| 90 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.86724001 |
| 91 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.86348772 |
| 92 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.86177005 |
| 93 | AR_20517297_ChIP-Seq_VCAP_Human | 0.85752419 |
| 94 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.85742901 |
| 95 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85348181 |
| 96 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.83777852 |
| 97 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.83557175 |
| 98 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82629596 |
| 99 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.82493158 |
| 100 | NFYB_21822215_ChIP-Seq_K562_Human | 0.81468742 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 5.67823938 |
| 2 | MP0000372_irregular_coat_pigmentation | 4.89741317 |
| 3 | MP0003806_abnormal_nucleotide_metabolis | 4.72762206 |
| 4 | MP0005451_abnormal_body_composition | 4.51225575 |
| 5 | MP0002132_abnormal_respiratory_system | 3.93362351 |
| 6 | MP0009379_abnormal_foot_pigmentation | 3.12540198 |
| 7 | MP0002736_abnormal_nociception_after | 2.92629125 |
| 8 | MP0002163_abnormal_gland_morphology | 2.89925071 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.70847986 |
| 10 | MP0005410_abnormal_fertilization | 2.52442729 |
| 11 | MP0002277_abnormal_respiratory_mucosa | 2.50042155 |
| 12 | MP0004381_abnormal_hair_follicle | 2.46533484 |
| 13 | MP0005671_abnormal_response_to | 2.45710342 |
| 14 | MP0001873_stomach_inflammation | 2.44312564 |
| 15 | MP0002102_abnormal_ear_morphology | 2.35250386 |
| 16 | MP0003763_abnormal_thymus_physiology | 2.33689694 |
| 17 | MP0002254_reproductive_system_inflammat | 2.32334965 |
| 18 | MP0003183_abnormal_peptide_metabolism | 2.05728686 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 1.99003980 |
| 20 | MP0006292_abnormal_olfactory_placode | 1.96724172 |
| 21 | MP0006035_abnormal_mitochondrial_morpho | 1.81413860 |
| 22 | MP0001968_abnormal_touch/_nociception | 1.72816233 |
| 23 | MP0003786_premature_aging | 1.66670680 |
| 24 | MP0005377_hearing/vestibular/ear_phenot | 1.53626329 |
| 25 | MP0003878_abnormal_ear_physiology | 1.53626329 |
| 26 | MP0009840_abnormal_foam_cell | 1.39216742 |
| 27 | MP0003718_maternal_effect | 1.37748588 |
| 28 | MP0000631_abnormal_neuroendocrine_gland | 1.37736393 |
| 29 | MP0003880_abnormal_central_pattern | 1.37332483 |
| 30 | MP0005379_endocrine/exocrine_gland_phen | 1.36775178 |
| 31 | MP0006036_abnormal_mitochondrial_physio | 1.34866978 |
| 32 | MP0003252_abnormal_bile_duct | 1.33746752 |
| 33 | MP0008872_abnormal_physiological_respon | 1.32919015 |
| 34 | MP0005083_abnormal_biliary_tract | 1.28470948 |
| 35 | MP0009697_abnormal_copulation | 1.26328198 |
| 36 | MP0003693_abnormal_embryo_hatching | 1.26286142 |
| 37 | MP0001881_abnormal_mammary_gland | 1.25438475 |
| 38 | MP0002234_abnormal_pharynx_morphology | 1.25421977 |
| 39 | MP0004147_increased_porphyrin_level | 1.23747309 |
| 40 | MP0005266_abnormal_metabolism | 1.20119885 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.18199055 |
| 42 | MP0005636_abnormal_mineral_homeostasis | 1.16552353 |
| 43 | MP0010386_abnormal_urinary_bladder | 1.16100180 |
| 44 | MP0003950_abnormal_plasma_membrane | 1.15198378 |
| 45 | MP0002733_abnormal_thermal_nociception | 1.12795054 |
| 46 | MP0004133_heterotaxia | 1.11959903 |
| 47 | MP0001501_abnormal_sleep_pattern | 1.09385118 |
| 48 | MP0008004_abnormal_stomach_pH | 1.04557476 |
| 49 | MP0001765_abnormal_ion_homeostasis | 1.03603660 |
| 50 | MP0003724_increased_susceptibility_to | 0.99774977 |
| 51 | MP0003866_abnormal_defecation | 0.98853864 |
| 52 | MP0002653_abnormal_ependyma_morphology | 0.92162045 |
| 53 | MP0005025_abnormal_response_to | 0.91767121 |
| 54 | MP0000604_amyloidosis | 0.89333993 |
| 55 | MP0006276_abnormal_autonomic_nervous | 0.87007147 |
| 56 | MP0003938_abnormal_ear_development | 0.86295439 |
| 57 | MP0002210_abnormal_sex_determination | 0.85663929 |
| 58 | MP0001905_abnormal_dopamine_level | 0.84666814 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 0.84076372 |
| 60 | MP0001666_abnormal_nutrient_absorption | 0.82937562 |
| 61 | MP0003698_abnormal_male_reproductive | 0.80979869 |
| 62 | MP0004019_abnormal_vitamin_homeostasis | 0.80588670 |
| 63 | MP0000490_abnormal_crypts_of | 0.79294781 |
| 64 | MP0009333_abnormal_splenocyte_physiolog | 0.79103059 |
| 65 | MP0002136_abnormal_kidney_physiology | 0.78900658 |
| 66 | MP0000230_abnormal_systemic_arterial | 0.77348024 |
| 67 | MP0005085_abnormal_gallbladder_physiolo | 0.77145296 |
| 68 | MP0001963_abnormal_hearing_physiology | 0.76491639 |
| 69 | MP0002693_abnormal_pancreas_physiology | 0.75370947 |
| 70 | MP0000358_abnormal_cell_content/ | 0.75108505 |
| 71 | MP0002723_abnormal_immune_serum | 0.74606348 |
| 72 | MP0002876_abnormal_thyroid_physiology | 0.73903197 |
| 73 | MP0003186_abnormal_redox_activity | 0.72554601 |
| 74 | MP0000026_abnormal_inner_ear | 0.72102968 |
| 75 | MP0001119_abnormal_female_reproductive | 0.71701488 |
| 76 | MP0000647_abnormal_sebaceous_gland | 0.71210030 |
| 77 | MP0001929_abnormal_gametogenesis | 0.70831401 |
| 78 | MP0005187_abnormal_penis_morphology | 0.70178135 |
| 79 | MP0002148_abnormal_hypersensitivity_rea | 0.69372834 |
| 80 | MP0001542_abnormal_bone_strength | 0.68575598 |
| 81 | MP0005171_absent_coat_pigmentation | 0.66477849 |
| 82 | MP0004885_abnormal_endolymph | 0.66101174 |
| 83 | MP0000383_abnormal_hair_follicle | 0.66073410 |
| 84 | MP0002837_dystrophic_cardiac_calcinosis | 0.65038964 |
| 85 | MP0003936_abnormal_reproductive_system | 0.64654989 |
| 86 | MP0002735_abnormal_chemical_nociception | 0.64196770 |
| 87 | MP0009643_abnormal_urine_homeostasis | 0.63491066 |
| 88 | MP0001663_abnormal_digestive_system | 0.62697265 |
| 89 | MP0001293_anophthalmia | 0.62507376 |
| 90 | MP0003011_delayed_dark_adaptation | 0.62328560 |
| 91 | MP0000049_abnormal_middle_ear | 0.62299892 |
| 92 | MP0000627_abnormal_mammary_gland | 0.57346129 |
| 93 | MP0000653_abnormal_sex_gland | 0.56842266 |
| 94 | MP0002933_joint_inflammation | 0.55602539 |
| 95 | MP0001800_abnormal_humoral_immune | 0.55498837 |
| 96 | MP0001286_abnormal_eye_development | 0.55395538 |
| 97 | MP0001970_abnormal_pain_threshold | 0.55056760 |
| 98 | MP0000716_abnormal_immune_system | 0.54213245 |
| 99 | MP0001819_abnormal_immune_cell | 0.53961863 |
| 100 | MP0001485_abnormal_pinna_reflex | 0.52014677 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sensory axonal neuropathy (HP:0003390) | 5.85487674 |
| 2 | Dysphonia (HP:0001618) | 5.64409497 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.98187303 |
| 4 | 3-Methylglutaconic aciduria (HP:0003535) | 4.83914152 |
| 5 | Testicular atrophy (HP:0000029) | 4.76986008 |
| 6 | Concave nail (HP:0001598) | 4.29905619 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.92685550 |
| 8 | Abnormality of B cell number (HP:0010975) | 3.82059847 |
| 9 | Flat capital femoral epiphysis (HP:0003370) | 3.79319579 |
| 10 | B lymphocytopenia (HP:0010976) | 3.61937799 |
| 11 | Acute encephalopathy (HP:0006846) | 3.52090158 |
| 12 | Limb dystonia (HP:0002451) | 3.48489159 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.43207728 |
| 14 | IgM deficiency (HP:0002850) | 3.30755340 |
| 15 | Microvesicular hepatic steatosis (HP:0001414) | 3.23662810 |
| 16 | Hypoplasia of the pons (HP:0012110) | 3.19671302 |
| 17 | IgG deficiency (HP:0004315) | 3.12366127 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.03449400 |
| 19 | Abnormal biliary tract physiology (HP:0012439) | 3.02055288 |
| 20 | Bile duct proliferation (HP:0001408) | 3.02055288 |
| 21 | Conical tooth (HP:0000698) | 2.96704038 |
| 22 | Dyschromatopsia (HP:0007641) | 2.86907723 |
| 23 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.85389068 |
| 24 | Abnormality of the renal cortex (HP:0011035) | 2.84578971 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.79831457 |
| 26 | Abnormality of the pons (HP:0007361) | 2.78679222 |
| 27 | Macrocytic anemia (HP:0001972) | 2.73968868 |
| 28 | Severe visual impairment (HP:0001141) | 2.73218205 |
| 29 | Polydipsia (HP:0001959) | 2.72376805 |
| 30 | Abnormal drinking behavior (HP:0030082) | 2.72376805 |
| 31 | Rough bone trabeculation (HP:0100670) | 2.66979392 |
| 32 | Mitochondrial inheritance (HP:0001427) | 2.61428972 |
| 33 | Abnormal number of erythroid precursors (HP:0012131) | 2.56729275 |
| 34 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.53166217 |
| 35 | Renal cortical cysts (HP:0000803) | 2.49769385 |
| 36 | Malnutrition (HP:0004395) | 2.44558289 |
| 37 | Severe combined immunodeficiency (HP:0004430) | 2.42778041 |
| 38 | Diastasis recti (HP:0001540) | 2.38905749 |
| 39 | Increased CSF lactate (HP:0002490) | 2.37551955 |
| 40 | Hyperlipoproteinemia (HP:0010980) | 2.36736231 |
| 41 | Nephronophthisis (HP:0000090) | 2.35294068 |
| 42 | Aplastic anemia (HP:0001915) | 2.35021522 |
| 43 | Cerebral edema (HP:0002181) | 2.34994002 |
| 44 | Poor speech (HP:0002465) | 2.34496273 |
| 45 | Abnormal hemoglobin (HP:0011902) | 2.33898300 |
| 46 | Thoracic kyphosis (HP:0002942) | 2.33804564 |
| 47 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.32865769 |
| 48 | Congenital sensorineural hearing impairment (HP:0008527) | 2.31416077 |
| 49 | Cerebral hypomyelination (HP:0006808) | 2.31011917 |
| 50 | Paralysis (HP:0003470) | 2.28866279 |
| 51 | Polyuria (HP:0000103) | 2.25787340 |
| 52 | Leukodystrophy (HP:0002415) | 2.19450946 |
| 53 | Tubular atrophy (HP:0000092) | 2.19264279 |
| 54 | Pallor (HP:0000980) | 2.18904530 |
| 55 | Resting tremor (HP:0002322) | 2.16739384 |
| 56 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.16584171 |
| 57 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.16490302 |
| 58 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.16490302 |
| 59 | Abnormal trabecular bone morphology (HP:0100671) | 2.13582704 |
| 60 | Prostate neoplasm (HP:0100787) | 2.12383822 |
| 61 | Fibular aplasia (HP:0002990) | 2.11901466 |
| 62 | Exercise intolerance (HP:0003546) | 2.10544936 |
| 63 | Parakeratosis (HP:0001036) | 2.08800450 |
| 64 | Hyperglycinuria (HP:0003108) | 2.05920555 |
| 65 | Pancytopenia (HP:0001876) | 2.04136112 |
| 66 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.03994899 |
| 67 | Stomatitis (HP:0010280) | 2.03008827 |
| 68 | Palpebral edema (HP:0100540) | 2.00919852 |
| 69 | Distal arthrogryposis (HP:0005684) | 1.99240305 |
| 70 | Type I diabetes mellitus (HP:0100651) | 1.98357595 |
| 71 | Sparse eyelashes (HP:0000653) | 1.97872864 |
| 72 | Abnormality of renal excretion (HP:0011036) | 1.95950269 |
| 73 | Increased intramyocellular lipid droplets (HP:0012240) | 1.95861565 |
| 74 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.95472703 |
| 75 | Respiratory difficulties (HP:0002880) | 1.94080268 |
| 76 | Abnormality of the renal medulla (HP:0100957) | 1.93163912 |
| 77 | Chronic diarrhea (HP:0002028) | 1.92211918 |
| 78 | Abnormal urine output (HP:0012590) | 1.91502636 |
| 79 | Bilateral microphthalmos (HP:0007633) | 1.89809880 |
| 80 | Optic disc pallor (HP:0000543) | 1.88833814 |
| 81 | Microretrognathia (HP:0000308) | 1.86553147 |
| 82 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.84773578 |
| 83 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.84375314 |
| 84 | Tubulointerstitial fibrosis (HP:0005576) | 1.84283704 |
| 85 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 1.82472913 |
| 86 | Impaired proprioception (HP:0010831) | 1.82286934 |
| 87 | Poor head control (HP:0002421) | 1.82149014 |
| 88 | Cellular immunodeficiency (HP:0005374) | 1.81304326 |
| 89 | Combined immunodeficiency (HP:0005387) | 1.80514430 |
| 90 | Xanthomatosis (HP:0000991) | 1.80115488 |
| 91 | Cortical visual impairment (HP:0100704) | 1.79747966 |
| 92 | Premature graying of hair (HP:0002216) | 1.76283155 |
| 93 | Type 2 muscle fiber atrophy (HP:0003554) | 1.76175198 |
| 94 | Oligodontia (HP:0000677) | 1.75091435 |
| 95 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.74941717 |
| 96 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.74757933 |
| 97 | Abnormality of the fovea (HP:0000493) | 1.73281661 |
| 98 | Nasolacrimal duct obstruction (HP:0000579) | 1.73171786 |
| 99 | Spastic paraparesis (HP:0002313) | 1.72694932 |
| 100 | Gastrointestinal stroma tumor (HP:0100723) | 1.71291769 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCYL2 | 6.90982674 |
| 2 | TESK2 | 5.47923998 |
| 3 | TLK1 | 4.28259724 |
| 4 | TESK1 | 3.90719515 |
| 5 | LIMK1 | 3.02140268 |
| 6 | KDR | 2.96943867 |
| 7 | PASK | 2.73844952 |
| 8 | WNK4 | 2.61007940 |
| 9 | EIF2AK1 | 2.56992285 |
| 10 | NUAK1 | 2.27373991 |
| 11 | TAOK2 | 2.20154630 |
| 12 | MAP3K12 | 2.13193034 |
| 13 | VRK1 | 2.10968630 |
| 14 | EPHA2 | 2.05764073 |
| 15 | ZAK | 1.96045324 |
| 16 | ITK | 1.69639457 |
| 17 | CDK19 | 1.69038902 |
| 18 | MYLK | 1.65674526 |
| 19 | EIF2AK3 | 1.61456058 |
| 20 | NEK1 | 1.54343671 |
| 21 | VRK2 | 1.42997705 |
| 22 | ZAP70 | 1.35167343 |
| 23 | INSRR | 1.29421599 |
| 24 | STK39 | 1.28045644 |
| 25 | CSK | 1.24791626 |
| 26 | NME2 | 1.19906748 |
| 27 | PINK1 | 1.19759292 |
| 28 | OXSR1 | 1.17827192 |
| 29 | BCKDK | 1.17405913 |
| 30 | ADRBK2 | 1.15759287 |
| 31 | DYRK3 | 1.12879109 |
| 32 | TEC | 1.11896877 |
| 33 | ERN1 | 1.10067721 |
| 34 | BRSK2 | 1.07686406 |
| 35 | ILK | 1.02783509 |
| 36 | RPS6KB2 | 0.91268808 |
| 37 | CAMKK2 | 0.88736676 |
| 38 | DAPK1 | 0.87346420 |
| 39 | TIE1 | 0.86107168 |
| 40 | TXK | 0.77624127 |
| 41 | ABL2 | 0.74235298 |
| 42 | CAMKK1 | 0.73917798 |
| 43 | BTK | 0.70093900 |
| 44 | GRK1 | 0.65667907 |
| 45 | MAPKAPK3 | 0.62577756 |
| 46 | GRK6 | 0.61876605 |
| 47 | MAP2K2 | 0.61752589 |
| 48 | AURKA | 0.59243020 |
| 49 | SRPK1 | 0.58177867 |
| 50 | CDK12 | 0.57451481 |
| 51 | PRKCQ | 0.56052648 |
| 52 | PRPF4B | 0.51427393 |
| 53 | DAPK3 | 0.49640426 |
| 54 | SYK | 0.49628516 |
| 55 | LCK | 0.49336581 |
| 56 | BLK | 0.48595396 |
| 57 | PRKAA2 | 0.47427628 |
| 58 | FLT3 | 0.47059990 |
| 59 | PRKCZ | 0.46772334 |
| 60 | MST4 | 0.45638786 |
| 61 | FES | 0.44212127 |
| 62 | AURKB | 0.41697625 |
| 63 | BRSK1 | 0.39623819 |
| 64 | PKN1 | 0.37317404 |
| 65 | DYRK2 | 0.35939479 |
| 66 | ADRBK1 | 0.35253979 |
| 67 | PRKCD | 0.33590636 |
| 68 | PDK2 | 0.33110113 |
| 69 | AKT2 | 0.32120460 |
| 70 | PLK1 | 0.31882356 |
| 71 | CAMK1 | 0.30683006 |
| 72 | PAK1 | 0.30265328 |
| 73 | PRKACA | 0.29434169 |
| 74 | CAMK2B | 0.29392686 |
| 75 | CAMK2G | 0.29003278 |
| 76 | HIPK2 | 0.28907167 |
| 77 | RPS6KA4 | 0.28851791 |
| 78 | MAPKAPK2 | 0.27674308 |
| 79 | RPS6KA5 | 0.27604025 |
| 80 | NME1 | 0.27385781 |
| 81 | PRKD1 | 0.27214092 |
| 82 | PAK4 | 0.26300850 |
| 83 | PRKCA | 0.25596516 |
| 84 | INSR | 0.25447092 |
| 85 | BMX | 0.23840249 |
| 86 | IKBKB | 0.23592056 |
| 87 | ROCK1 | 0.23106783 |
| 88 | CSNK2A1 | 0.23050949 |
| 89 | NEK6 | 0.21594284 |
| 90 | PLK3 | 0.21219015 |
| 91 | PIK3CG | 0.20293227 |
| 92 | IGF1R | 0.19922972 |
| 93 | TYRO3 | 0.19892427 |
| 94 | CHEK2 | 0.19779188 |
| 95 | PRKCI | 0.19255368 |
| 96 | IKBKE | 0.19155748 |
| 97 | PRKD2 | 0.16858417 |
| 98 | MAP3K11 | 0.16723923 |
| 99 | MAP3K8 | 0.15834312 |
| 100 | CAMK1D | 0.15637494 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.73173751 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.33523537 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.62295829 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.50766383 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.89190288 |
| 6 | Sulfur relay system_Homo sapiens_hsa04122 | 2.87050979 |
| 7 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.35885893 |
| 8 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.18582715 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.14332534 |
| 10 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.96218171 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 1.88059358 |
| 12 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.86320116 |
| 13 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.81656908 |
| 14 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.78718380 |
| 15 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.73992732 |
| 16 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.69137845 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.66528965 |
| 18 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.64115322 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.63109051 |
| 20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.56670357 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.55916820 |
| 22 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.51214123 |
| 23 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.48406400 |
| 24 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.46005316 |
| 25 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.44401446 |
| 26 | Protein export_Homo sapiens_hsa03060 | 1.41536509 |
| 27 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.37127492 |
| 28 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.33216370 |
| 29 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.32315387 |
| 30 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.21530117 |
| 31 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.20142442 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.17794150 |
| 33 | Histidine metabolism_Homo sapiens_hsa00340 | 1.14352320 |
| 34 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.12774480 |
| 35 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.12748868 |
| 36 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.11361972 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.08505677 |
| 38 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.05769957 |
| 39 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.04526611 |
| 40 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.02942967 |
| 41 | Retinol metabolism_Homo sapiens_hsa00830 | 1.01418282 |
| 42 | Spliceosome_Homo sapiens_hsa03040 | 1.01407917 |
| 43 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.99774454 |
| 44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.96899288 |
| 45 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.96855354 |
| 46 | Base excision repair_Homo sapiens_hsa03410 | 0.96643464 |
| 47 | Legionellosis_Homo sapiens_hsa05134 | 0.94045867 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.93683965 |
| 49 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.93053356 |
| 50 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.88715860 |
| 51 | RNA degradation_Homo sapiens_hsa03018 | 0.86698078 |
| 52 | Homologous recombination_Homo sapiens_hsa03440 | 0.84427408 |
| 53 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.80862656 |
| 54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.79782815 |
| 55 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.78944882 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.76377977 |
| 57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75738519 |
| 58 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72642603 |
| 59 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.71381697 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.70654838 |
| 61 | DNA replication_Homo sapiens_hsa03030 | 0.69401867 |
| 62 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.67276447 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66264490 |
| 64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64727866 |
| 65 | Galactose metabolism_Homo sapiens_hsa00052 | 0.64190562 |
| 66 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.60992149 |
| 67 | Basal transcription factors_Homo sapiens_hsa03022 | 0.53870494 |
| 68 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.53851846 |
| 69 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.51058633 |
| 70 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.50922845 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.49707598 |
| 72 | RNA polymerase_Homo sapiens_hsa03020 | 0.48724478 |
| 73 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.47513732 |
| 74 | Malaria_Homo sapiens_hsa05144 | 0.46555342 |
| 75 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.45922477 |
| 76 | RNA transport_Homo sapiens_hsa03013 | 0.45675167 |
| 77 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.44519503 |
| 78 | Phototransduction_Homo sapiens_hsa04744 | 0.40800803 |
| 79 | Shigellosis_Homo sapiens_hsa05131 | 0.40339698 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.38503331 |
| 81 | Measles_Homo sapiens_hsa05162 | 0.33479911 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31384582 |
| 83 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.30524754 |
| 84 | Apoptosis_Homo sapiens_hsa04210 | 0.27758052 |
| 85 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.26260127 |
| 86 | Circadian rhythm_Homo sapiens_hsa04710 | 0.25219929 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.25106671 |
| 88 | Allograft rejection_Homo sapiens_hsa05330 | 0.23756550 |
| 89 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.23590615 |
| 90 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.23548111 |
| 91 | Mineral absorption_Homo sapiens_hsa04978 | 0.21581938 |
| 92 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.20166184 |
| 93 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.19453860 |
| 94 | Olfactory transduction_Homo sapiens_hsa04740 | 0.19413105 |
| 95 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.18868738 |
| 96 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.18145569 |
| 97 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.17987962 |
| 98 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.16540494 |
| 99 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.16433574 |
| 100 | Mismatch repair_Homo sapiens_hsa03430 | 0.15035728 |

