

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of DNA endoreduplication (GO:0032875) | 4.80375167 |
| 2 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.80128664 |
| 3 | DNA strand elongation (GO:0022616) | 4.56077030 |
| 4 | nuclear pore complex assembly (GO:0051292) | 4.46308374 |
| 5 | DNA ligation (GO:0006266) | 4.41730463 |
| 6 | proteasome assembly (GO:0043248) | 4.38249043 |
| 7 | DNA unwinding involved in DNA replication (GO:0006268) | 4.36808731 |
| 8 | DNA topological change (GO:0006265) | 4.30522735 |
| 9 | DNA replication initiation (GO:0006270) | 4.27374939 |
| 10 | kinetochore organization (GO:0051383) | 4.17331719 |
| 11 | kinetochore assembly (GO:0051382) | 4.15676111 |
| 12 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.15300573 |
| 13 | nuclear pore organization (GO:0006999) | 4.05142402 |
| 14 | CENP-A containing nucleosome assembly (GO:0034080) | 4.04240278 |
| 15 | regulation of mitochondrial translation (GO:0070129) | 4.01306191 |
| 16 | DNA replication checkpoint (GO:0000076) | 4.00992302 |
| 17 | chromatin remodeling at centromere (GO:0031055) | 3.95514450 |
| 18 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.93548706 |
| 19 | viral mRNA export from host cell nucleus (GO:0046784) | 3.92147263 |
| 20 | replication fork processing (GO:0031297) | 3.89589838 |
| 21 | protein-cofactor linkage (GO:0018065) | 3.87979758 |
| 22 | ribosome biogenesis (GO:0042254) | 3.84971388 |
| 23 | chaperone-mediated protein transport (GO:0072321) | 3.84375428 |
| 24 | DNA strand renaturation (GO:0000733) | 3.82156289 |
| 25 | respiratory chain complex IV assembly (GO:0008535) | 3.77708648 |
| 26 | maturation of SSU-rRNA (GO:0030490) | 3.76986674 |
| 27 | pore complex assembly (GO:0046931) | 3.63786493 |
| 28 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.63342445 |
| 29 | mitotic metaphase plate congression (GO:0007080) | 3.60698596 |
| 30 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.58542204 |
| 31 | telomere maintenance via recombination (GO:0000722) | 3.57616865 |
| 32 | termination of RNA polymerase I transcription (GO:0006363) | 3.55575436 |
| 33 | protein localization to kinetochore (GO:0034501) | 3.48966022 |
| 34 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.44965607 |
| 35 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.44871891 |
| 36 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.44340308 |
| 37 | mitotic recombination (GO:0006312) | 3.41886881 |
| 38 | ribosomal small subunit assembly (GO:0000028) | 3.39643415 |
| 39 | metaphase plate congression (GO:0051310) | 3.37898463 |
| 40 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.37228216 |
| 41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.36148310 |
| 42 | microtubule depolymerization (GO:0007019) | 3.32109545 |
| 43 | cellular component biogenesis (GO:0044085) | 3.31219457 |
| 44 | translational termination (GO:0006415) | 3.30969646 |
| 45 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.30009068 |
| 46 | cytochrome complex assembly (GO:0017004) | 3.28956915 |
| 47 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.28905419 |
| 48 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.28905419 |
| 49 | protein complex biogenesis (GO:0070271) | 3.27306248 |
| 50 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.27110211 |
| 51 | DNA replication-independent nucleosome organization (GO:0034724) | 3.26914172 |
| 52 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.26914172 |
| 53 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.26633233 |
| 54 | granulocyte differentiation (GO:0030851) | 3.26551206 |
| 55 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.25489224 |
| 56 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.25489224 |
| 57 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.25489224 |
| 58 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.25037495 |
| 59 | inner mitochondrial membrane organization (GO:0007007) | 3.23773234 |
| 60 | histone exchange (GO:0043486) | 3.22787968 |
| 61 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.22080319 |
| 62 | negative regulation of ligase activity (GO:0051352) | 3.22080319 |
| 63 | viral transcription (GO:0019083) | 3.20861562 |
| 64 | mitotic nuclear envelope disassembly (GO:0007077) | 3.18573141 |
| 65 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.16845313 |
| 66 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.16845313 |
| 67 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.16469304 |
| 68 | spindle checkpoint (GO:0031577) | 3.14403353 |
| 69 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.12623968 |
| 70 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.12623968 |
| 71 | GMP metabolic process (GO:0046037) | 3.12435562 |
| 72 | positive regulation of ligase activity (GO:0051351) | 3.09062955 |
| 73 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.08184447 |
| 74 | sister chromatid cohesion (GO:0007062) | 3.07906909 |
| 75 | transcription from RNA polymerase I promoter (GO:0006360) | 3.07378596 |
| 76 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.06349462 |
| 77 | ATP synthesis coupled proton transport (GO:0015986) | 3.02269531 |
| 78 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.02269531 |
| 79 | ribosomal small subunit biogenesis (GO:0042274) | 2.97340083 |
| 80 | sister chromatid segregation (GO:0000819) | 2.94679327 |
| 81 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.94180159 |
| 82 | NADH dehydrogenase complex assembly (GO:0010257) | 2.94180159 |
| 83 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.94180159 |
| 84 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.93066516 |
| 85 | telomere maintenance via telomere lengthening (GO:0010833) | 2.92675733 |
| 86 | mitotic spindle assembly checkpoint (GO:0007094) | 2.92010365 |
| 87 | negative regulation of chromosome segregation (GO:0051985) | 2.91274312 |
| 88 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.91099560 |
| 89 | spindle assembly checkpoint (GO:0071173) | 2.90383518 |
| 90 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.88661368 |
| 91 | oxidative phosphorylation (GO:0006119) | 2.88491396 |
| 92 | resolution of meiotic recombination intermediates (GO:0000712) | 2.88470222 |
| 93 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.87760287 |
| 94 | negative regulation of sister chromatid segregation (GO:0033046) | 2.87760287 |
| 95 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.87760287 |
| 96 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.87760287 |
| 97 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.87760287 |
| 98 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.87037379 |
| 99 | synapsis (GO:0007129) | 2.86934745 |
| 100 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.86235684 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.15482456 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.34256347 |
| 3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.09391522 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.00457927 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.85287444 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.74974913 |
| 7 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.53538016 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.49304214 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.46338953 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.30702082 |
| 11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.13456800 |
| 12 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.88784631 |
| 13 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.85830837 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.70053874 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.63008401 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.60106792 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.59790051 |
| 18 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.50122428 |
| 19 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.49914100 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.40522824 |
| 21 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.35186006 |
| 22 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.33598794 |
| 23 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.27890137 |
| 24 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.27167997 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.26256324 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.25376903 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.25103096 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.19816429 |
| 29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.14704355 |
| 30 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.14316242 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.10342356 |
| 32 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.04236319 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.99848396 |
| 34 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.99001048 |
| 35 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.94718362 |
| 36 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.93944586 |
| 37 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.86052904 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.81769488 |
| 39 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.80409711 |
| 40 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.77571411 |
| 41 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.70863607 |
| 42 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.64281295 |
| 43 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.62956062 |
| 44 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.56256551 |
| 45 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.55779338 |
| 46 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.55715591 |
| 47 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.52378035 |
| 48 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.50718032 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.49545430 |
| 50 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.48326095 |
| 51 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.47746262 |
| 52 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.42548832 |
| 53 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.42357208 |
| 54 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33762200 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.26256556 |
| 56 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.24279358 |
| 57 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21348374 |
| 58 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.20758373 |
| 59 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.20529725 |
| 60 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20237104 |
| 61 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.18176875 |
| 62 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.16185177 |
| 63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.15395992 |
| 64 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.13744688 |
| 65 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.10075514 |
| 66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.09616279 |
| 67 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.09420222 |
| 68 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.07544662 |
| 69 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.05009867 |
| 70 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.04477587 |
| 71 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.04470152 |
| 72 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.01984877 |
| 73 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.00894129 |
| 74 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.98183727 |
| 75 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.96738823 |
| 76 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.95769214 |
| 77 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.94289802 |
| 78 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.93046748 |
| 79 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90378925 |
| 80 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.90052926 |
| 81 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.88811025 |
| 82 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88385548 |
| 83 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.88010265 |
| 84 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.87478155 |
| 85 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.85147382 |
| 86 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.84793763 |
| 87 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.84301534 |
| 88 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83404999 |
| 89 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.81694635 |
| 90 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.80242458 |
| 91 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.76131664 |
| 92 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.75166865 |
| 93 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.71761192 |
| 94 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.70415554 |
| 95 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.66306222 |
| 96 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.66070657 |
| 97 | GATA1_19941826_ChIP-Seq_K562_Human | 0.63763219 |
| 98 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.63664586 |
| 99 | GATA1_22025678_ChIP-Seq_K562_Human | 0.63635283 |
| 100 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.61847989 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.31920821 |
| 2 | MP0008058_abnormal_DNA_repair | 4.27859270 |
| 3 | MP0010094_abnormal_chromosome_stability | 4.25328347 |
| 4 | MP0003111_abnormal_nucleus_morphology | 3.55496775 |
| 5 | MP0009697_abnormal_copulation | 3.18681774 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 2.98653437 |
| 7 | MP0006035_abnormal_mitochondrial_morpho | 2.87685622 |
| 8 | MP0003646_muscle_fatigue | 2.71314873 |
| 9 | MP0008057_abnormal_DNA_replication | 2.70891029 |
| 10 | MP0003077_abnormal_cell_cycle | 2.48986001 |
| 11 | MP0001661_extended_life_span | 2.45704348 |
| 12 | MP0006054_spinal_hemorrhage | 2.43495755 |
| 13 | MP0003950_abnormal_plasma_membrane | 2.37339112 |
| 14 | MP0008932_abnormal_embryonic_tissue | 2.29772550 |
| 15 | MP0003806_abnormal_nucleotide_metabolis | 2.25554039 |
| 16 | MP0002132_abnormal_respiratory_system | 2.20412284 |
| 17 | MP0003186_abnormal_redox_activity | 2.11236495 |
| 18 | MP0000358_abnormal_cell_content/ | 2.08758966 |
| 19 | MP0003136_yellow_coat_color | 2.07960388 |
| 20 | MP0002396_abnormal_hematopoietic_system | 2.03418430 |
| 21 | MP0008995_early_reproductive_senescence | 1.93037298 |
| 22 | MP0003786_premature_aging | 1.86290972 |
| 23 | MP0004185_abnormal_adipocyte_glucose | 1.83655615 |
| 24 | MP0008007_abnormal_cellular_replicative | 1.83333149 |
| 25 | MP0004808_abnormal_hematopoietic_stem | 1.81062002 |
| 26 | MP0006036_abnormal_mitochondrial_physio | 1.77606615 |
| 27 | MP0002160_abnormal_reproductive_system | 1.71661669 |
| 28 | MP0003718_maternal_effect | 1.61648296 |
| 29 | MP0004147_increased_porphyrin_level | 1.56286604 |
| 30 | MP0003195_calcinosis | 1.50059233 |
| 31 | MP0005380_embryogenesis_phenotype | 1.49390499 |
| 32 | MP0001672_abnormal_embryogenesis/_devel | 1.49390499 |
| 33 | MP0001697_abnormal_embryo_size | 1.48794496 |
| 34 | MP0003984_embryonic_growth_retardation | 1.47743654 |
| 35 | MP0000313_abnormal_cell_death | 1.45260319 |
| 36 | MP0002088_abnormal_embryonic_growth/wei | 1.44923628 |
| 37 | MP0008260_abnormal_autophagy | 1.44829290 |
| 38 | MP0000569_abnormal_digit_pigmentation | 1.41958491 |
| 39 | MP0002210_abnormal_sex_determination | 1.41475422 |
| 40 | MP0002269_muscular_atrophy | 1.40467831 |
| 41 | MP0001243_abnormal_dermal_layer | 1.35109957 |
| 42 | MP0001929_abnormal_gametogenesis | 1.34226164 |
| 43 | MP0000350_abnormal_cell_proliferation | 1.33784366 |
| 44 | MP0000751_myopathy | 1.32322701 |
| 45 | MP0005408_hypopigmentation | 1.32233580 |
| 46 | MP0010307_abnormal_tumor_latency | 1.29282558 |
| 47 | MP0000015_abnormal_ear_pigmentation | 1.26524517 |
| 48 | MP0002080_prenatal_lethality | 1.25746025 |
| 49 | MP0001730_embryonic_growth_arrest | 1.24175055 |
| 50 | MP0006292_abnormal_olfactory_placode | 1.14521996 |
| 51 | MP0000749_muscle_degeneration | 1.11959178 |
| 52 | MP0001545_abnormal_hematopoietic_system | 1.11586692 |
| 53 | MP0005397_hematopoietic_system_phenotyp | 1.11586692 |
| 54 | MP0002837_dystrophic_cardiac_calcinosis | 1.09286559 |
| 55 | MP0003959_abnormal_lean_body | 1.07723952 |
| 56 | MP0002138_abnormal_hepatobiliary_system | 1.05454917 |
| 57 | MP0004084_abnormal_cardiac_muscle | 1.04219161 |
| 58 | MP0005501_abnormal_skin_physiology | 1.03701294 |
| 59 | MP0009379_abnormal_foot_pigmentation | 1.01105556 |
| 60 | MP0000372_irregular_coat_pigmentation | 0.97360575 |
| 61 | MP0003698_abnormal_male_reproductive | 0.97232076 |
| 62 | MP0002938_white_spotting | 0.96433337 |
| 63 | MP0002019_abnormal_tumor_incidence | 0.94846759 |
| 64 | MP0002086_abnormal_extraembryonic_tissu | 0.94096456 |
| 65 | MP0001145_abnormal_male_reproductive | 0.93515577 |
| 66 | MP0002084_abnormal_developmental_patter | 0.90438103 |
| 67 | MP0000653_abnormal_sex_gland | 0.89269440 |
| 68 | MP0003011_delayed_dark_adaptation | 0.89139071 |
| 69 | MP0002085_abnormal_embryonic_tissue | 0.88684727 |
| 70 | MP0005058_abnormal_lysosome_morphology | 0.85901186 |
| 71 | MP0005666_abnormal_adipose_tissue | 0.85194407 |
| 72 | MP0000747_muscle_weakness | 0.84326377 |
| 73 | MP0005319_abnormal_enzyme/_coenzyme | 0.83438830 |
| 74 | MP0005409_darkened_coat_color | 0.83314199 |
| 75 | MP0005075_abnormal_melanosome_morpholog | 0.83238142 |
| 76 | MP0005395_other_phenotype | 0.81830990 |
| 77 | MP0002111_abnormal_tail_morphology | 0.80866844 |
| 78 | MP0002095_abnormal_skin_pigmentation | 0.79560299 |
| 79 | MP0005384_cellular_phenotype | 0.78704686 |
| 80 | MP0001299_abnormal_eye_distance/ | 0.77975509 |
| 81 | MP0005670_abnormal_white_adipose | 0.77248951 |
| 82 | MP0005389_reproductive_system_phenotype | 0.76825087 |
| 83 | MP0002653_abnormal_ependyma_morphology | 0.76590415 |
| 84 | MP0003121_genomic_imprinting | 0.75734868 |
| 85 | MP0001727_abnormal_embryo_implantation | 0.74789748 |
| 86 | MP0001881_abnormal_mammary_gland | 0.74458345 |
| 87 | MP0000371_diluted_coat_color | 0.73990333 |
| 88 | MP0003890_abnormal_embryonic-extraembry | 0.73137969 |
| 89 | MP0005083_abnormal_biliary_tract | 0.72443869 |
| 90 | MP0003699_abnormal_female_reproductive | 0.71091083 |
| 91 | MP0010630_abnormal_cardiac_muscle | 0.68432241 |
| 92 | MP0000703_abnormal_thymus_morphology | 0.68348572 |
| 93 | MP0004197_abnormal_fetal_growth/weight/ | 0.67926775 |
| 94 | MP0002161_abnormal_fertility/fecundity | 0.66668215 |
| 95 | MP0001915_intracranial_hemorrhage | 0.65633676 |
| 96 | MP0005174_abnormal_tail_pigmentation | 0.64757049 |
| 97 | MP0002127_abnormal_cardiovascular_syste | 0.63022285 |
| 98 | MP0004130_abnormal_muscle_cell | 0.62383123 |
| 99 | MP0002970_abnormal_white_adipose | 0.61517777 |
| 100 | MP0002108_abnormal_muscle_morphology | 0.61089462 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 4.44120364 |
| 2 | Abnormal number of erythroid precursors (HP:0012131) | 4.16565438 |
| 3 | Birth length less than 3rd percentile (HP:0003561) | 4.04396481 |
| 4 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.04025630 |
| 5 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.94138941 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.79203037 |
| 7 | Chromsome breakage (HP:0040012) | 3.63021506 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.59877493 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.45966582 |
| 10 | Abnormality of reticulocytes (HP:0004312) | 3.38513942 |
| 11 | Urethral obstruction (HP:0000796) | 3.36113970 |
| 12 | Absent thumb (HP:0009777) | 3.24966419 |
| 13 | Abnormality of DNA repair (HP:0003254) | 3.15413289 |
| 14 | Mitochondrial inheritance (HP:0001427) | 3.03486774 |
| 15 | Increased CSF lactate (HP:0002490) | 2.99605666 |
| 16 | Acute encephalopathy (HP:0006846) | 2.98051580 |
| 17 | Macrocytic anemia (HP:0001972) | 2.95631348 |
| 18 | Abnormality of chromosome stability (HP:0003220) | 2.91056290 |
| 19 | Hepatocellular necrosis (HP:0001404) | 2.89829947 |
| 20 | Reticulocytosis (HP:0001923) | 2.88489847 |
| 21 | Short middle phalanx of the 5th finger (HP:0004220) | 2.88475847 |
| 22 | Pallor (HP:0000980) | 2.85068140 |
| 23 | Homocystinuria (HP:0002156) | 2.85025910 |
| 24 | Abnormality of homocysteine metabolism (HP:0010919) | 2.85025910 |
| 25 | Redundant skin (HP:0001582) | 2.83509731 |
| 26 | Sensory axonal neuropathy (HP:0003390) | 2.74824929 |
| 27 | Tinnitus (HP:0000360) | 2.71653115 |
| 28 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.71474079 |
| 29 | Small intestinal stenosis (HP:0012848) | 2.70964578 |
| 30 | Duodenal stenosis (HP:0100867) | 2.70964578 |
| 31 | Volvulus (HP:0002580) | 2.68766266 |
| 32 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.66044565 |
| 33 | Ileus (HP:0002595) | 2.64791741 |
| 34 | Ectopic kidney (HP:0000086) | 2.63253084 |
| 35 | Pustule (HP:0200039) | 2.61165959 |
| 36 | Thoracic kyphosis (HP:0002942) | 2.60379802 |
| 37 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.54730109 |
| 38 | Brushfield spots (HP:0001088) | 2.51097424 |
| 39 | Meckel diverticulum (HP:0002245) | 2.49580722 |
| 40 | Acanthocytosis (HP:0001927) | 2.49431697 |
| 41 | Short 5th finger (HP:0009237) | 2.46538218 |
| 42 | Microvesicular hepatic steatosis (HP:0001414) | 2.45862528 |
| 43 | Abnormality of the preputium (HP:0100587) | 2.45859769 |
| 44 | Cellular immunodeficiency (HP:0005374) | 2.45393976 |
| 45 | Horseshoe kidney (HP:0000085) | 2.42920700 |
| 46 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.38775606 |
| 47 | Poikilocytosis (HP:0004447) | 2.35567395 |
| 48 | Cerebral edema (HP:0002181) | 2.34114792 |
| 49 | Epiphyseal stippling (HP:0010655) | 2.33630312 |
| 50 | Delusions (HP:0000746) | 2.33488326 |
| 51 | Long clavicles (HP:0000890) | 2.31364435 |
| 52 | Tubulointerstitial nephritis (HP:0001970) | 2.30821155 |
| 53 | Acute myeloid leukemia (HP:0004808) | 2.30158530 |
| 54 | Hepatic necrosis (HP:0002605) | 2.28457801 |
| 55 | Respiratory difficulties (HP:0002880) | 2.28006540 |
| 56 | Abnormality of the duodenum (HP:0002246) | 2.27699715 |
| 57 | Orthostatic hypotension (HP:0001278) | 2.25713975 |
| 58 | Abnormality of the ileum (HP:0001549) | 2.25500404 |
| 59 | Polycythemia (HP:0001901) | 2.25444530 |
| 60 | Beaking of vertebral bodies (HP:0004568) | 2.25278198 |
| 61 | Ependymoma (HP:0002888) | 2.24349334 |
| 62 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.23146146 |
| 63 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.23028685 |
| 64 | Absent epiphyses (HP:0010577) | 2.23028685 |
| 65 | Myelodysplasia (HP:0002863) | 2.22717740 |
| 66 | Truncus arteriosus (HP:0001660) | 2.18172145 |
| 67 | Ulnar deviation of the wrist (HP:0003049) | 2.15681484 |
| 68 | Duplicated collecting system (HP:0000081) | 2.14437804 |
| 69 | Thyroid-stimulating hormone excess (HP:0002925) | 2.12782957 |
| 70 | Hyperthyroidism (HP:0000836) | 2.12701488 |
| 71 | Severe combined immunodeficiency (HP:0004430) | 2.06930263 |
| 72 | Respiratory failure (HP:0002878) | 2.05226629 |
| 73 | Hypoplasia of the pons (HP:0012110) | 2.05182534 |
| 74 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.04226982 |
| 75 | Abnormal epiphyseal ossification (HP:0010656) | 2.03195784 |
| 76 | Combined immunodeficiency (HP:0005387) | 2.03167057 |
| 77 | Abnormality of the carotid arteries (HP:0005344) | 2.02053447 |
| 78 | Clubbing of toes (HP:0100760) | 2.01529940 |
| 79 | Irregular epiphyses (HP:0010582) | 2.00128177 |
| 80 | Abnormal gallbladder physiology (HP:0012438) | 1.97298169 |
| 81 | Cholecystitis (HP:0001082) | 1.97298169 |
| 82 | Type I transferrin isoform profile (HP:0003642) | 1.96987787 |
| 83 | Abnormal number of incisors (HP:0011064) | 1.95919905 |
| 84 | CNS demyelination (HP:0007305) | 1.94387816 |
| 85 | Sloping forehead (HP:0000340) | 1.92977648 |
| 86 | Cerebral hypomyelination (HP:0006808) | 1.89791963 |
| 87 | Progressive external ophthalmoplegia (HP:0000590) | 1.89583823 |
| 88 | Short thumb (HP:0009778) | 1.89342569 |
| 89 | Exercise intolerance (HP:0003546) | 1.88561362 |
| 90 | Neutropenia (HP:0001875) | 1.88163267 |
| 91 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.87302121 |
| 92 | Pulmonary artery stenosis (HP:0004415) | 1.85688776 |
| 93 | Abnormality of the renal collecting system (HP:0004742) | 1.85210140 |
| 94 | Short chin (HP:0000331) | 1.84366844 |
| 95 | Hypoparathyroidism (HP:0000829) | 1.84311361 |
| 96 | Abnormality of dental color (HP:0011073) | 1.84139393 |
| 97 | Leukodystrophy (HP:0002415) | 1.83975713 |
| 98 | Hypoplastic iliac wings (HP:0002866) | 1.83564283 |
| 99 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.78369700 |
| 100 | Hypertensive crisis (HP:0100735) | 1.77431841 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK3 | 4.28701542 |
| 2 | PDK2 | 3.97123384 |
| 3 | PBK | 3.51182164 |
| 4 | EIF2AK1 | 3.19277824 |
| 5 | ZAK | 2.87192204 |
| 6 | MAPKAPK3 | 2.86553603 |
| 7 | TTK | 2.85577284 |
| 8 | MST4 | 2.71394694 |
| 9 | FRK | 2.58379407 |
| 10 | STK4 | 2.34731824 |
| 11 | STK10 | 2.28945463 |
| 12 | CDC7 | 2.24632100 |
| 13 | BUB1 | 2.17659395 |
| 14 | STK16 | 2.10737851 |
| 15 | PLK2 | 2.09766718 |
| 16 | PLK4 | 2.03802665 |
| 17 | VRK2 | 1.97332575 |
| 18 | PRKCI | 1.93328173 |
| 19 | NME1 | 1.84098787 |
| 20 | RIPK1 | 1.77486407 |
| 21 | PLK3 | 1.65931751 |
| 22 | CDK8 | 1.62752897 |
| 23 | MAP4K2 | 1.57345942 |
| 24 | CHEK2 | 1.57345718 |
| 25 | FLT3 | 1.54563713 |
| 26 | BRSK1 | 1.53034266 |
| 27 | PLK1 | 1.47674557 |
| 28 | NEK2 | 1.47264678 |
| 29 | BRSK2 | 1.41150430 |
| 30 | RAF1 | 1.36702727 |
| 31 | WEE1 | 1.32085999 |
| 32 | CDK12 | 1.30833423 |
| 33 | NEK1 | 1.30398014 |
| 34 | SRPK1 | 1.26921947 |
| 35 | ATR | 1.25149644 |
| 36 | TAF1 | 1.22849897 |
| 37 | RIPK4 | 1.20805156 |
| 38 | AURKB | 1.20571791 |
| 39 | KIT | 1.17104327 |
| 40 | CCNB1 | 1.16462434 |
| 41 | CLK1 | 1.11599244 |
| 42 | RPS6KB2 | 1.05880538 |
| 43 | EIF2AK2 | 1.03924299 |
| 44 | MAP3K8 | 1.03628233 |
| 45 | LRRK2 | 1.03275004 |
| 46 | RPS6KA4 | 0.86121263 |
| 47 | TRPM7 | 0.80206322 |
| 48 | TAOK1 | 0.79375271 |
| 49 | CDK7 | 0.78159746 |
| 50 | OXSR1 | 0.76002110 |
| 51 | NUAK1 | 0.74630505 |
| 52 | CSNK2A2 | 0.74008932 |
| 53 | NLK | 0.72889510 |
| 54 | CHEK1 | 0.72450248 |
| 55 | ATM | 0.72311271 |
| 56 | WNK4 | 0.67556350 |
| 57 | ALK | 0.67280939 |
| 58 | TYRO3 | 0.66967554 |
| 59 | MAP3K10 | 0.66664333 |
| 60 | DAPK1 | 0.61481595 |
| 61 | CDK2 | 0.60531263 |
| 62 | CAMK1G | 0.60509154 |
| 63 | PIM2 | 0.57603449 |
| 64 | CSNK1E | 0.57068471 |
| 65 | KSR2 | 0.56820923 |
| 66 | TNIK | 0.56577999 |
| 67 | SCYL2 | 0.55916642 |
| 68 | CAMK1D | 0.55589443 |
| 69 | DYRK2 | 0.54736990 |
| 70 | VRK1 | 0.54292636 |
| 71 | MARK3 | 0.53401956 |
| 72 | STK38 | 0.52992327 |
| 73 | BRAF | 0.52230504 |
| 74 | EEF2K | 0.51199315 |
| 75 | BRD4 | 0.50367594 |
| 76 | CSNK2A1 | 0.50209566 |
| 77 | PAK1 | 0.48844354 |
| 78 | CSNK1G3 | 0.44374754 |
| 79 | IRAK3 | 0.43763874 |
| 80 | CDK1 | 0.43299032 |
| 81 | PTK2B | 0.42194978 |
| 82 | CAMK1 | 0.41799661 |
| 83 | PAK4 | 0.39289924 |
| 84 | MAP3K7 | 0.38755773 |
| 85 | AKT3 | 0.37686180 |
| 86 | ERBB2 | 0.35936243 |
| 87 | CDK4 | 0.35843803 |
| 88 | NEK6 | 0.35184786 |
| 89 | SGK1 | 0.32486204 |
| 90 | AKT2 | 0.27959607 |
| 91 | CASK | 0.27940159 |
| 92 | STK11 | 0.24637625 |
| 93 | ADRBK1 | 0.24312298 |
| 94 | PHKG1 | 0.23089257 |
| 95 | PHKG2 | 0.23089257 |
| 96 | PAK2 | 0.21625563 |
| 97 | ARAF | 0.21622950 |
| 98 | PRKG2 | 0.21141325 |
| 99 | FGFR2 | 0.20571971 |
| 100 | CAMK4 | 0.18105573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.46989851 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.28980330 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 4.14003281 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.37445825 |
| 5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.31327949 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.90248743 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.72039297 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.71411622 |
| 9 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.71084690 |
| 10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.62778575 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.54100690 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.48990177 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.29737623 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 2.28846185 |
| 15 | Base excision repair_Homo sapiens_hsa03410 | 2.24955436 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.24139057 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 2.13309627 |
| 18 | Cell cycle_Homo sapiens_hsa04110 | 2.10950383 |
| 19 | Basal transcription factors_Homo sapiens_hsa03022 | 2.09676989 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.97679177 |
| 21 | Protein export_Homo sapiens_hsa03060 | 1.72899693 |
| 22 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.64756219 |
| 23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.61114645 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.54061456 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.42743912 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.37151006 |
| 27 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.29433077 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.28388279 |
| 29 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.27317763 |
| 30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.24413666 |
| 31 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.23544108 |
| 32 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.20949885 |
| 33 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.19023466 |
| 34 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.16046430 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.12418687 |
| 36 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.11462209 |
| 37 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.06299981 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.02382851 |
| 39 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.99020708 |
| 40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.90131629 |
| 41 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.90014067 |
| 42 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.87878540 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.86553055 |
| 44 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.85300343 |
| 45 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.78807134 |
| 46 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.77680308 |
| 47 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.75325361 |
| 48 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.74534401 |
| 49 | Lysine degradation_Homo sapiens_hsa00310 | 0.71098011 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69472671 |
| 51 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.68697605 |
| 52 | Thyroid cancer_Homo sapiens_hsa05216 | 0.66585185 |
| 53 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.62232831 |
| 54 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59354491 |
| 55 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.57099402 |
| 56 | Carbon metabolism_Homo sapiens_hsa01200 | 0.57025988 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55422048 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52731743 |
| 59 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.51429300 |
| 60 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.49901668 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.49414260 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.46321786 |
| 63 | Sulfur relay system_Homo sapiens_hsa04122 | 0.44420238 |
| 64 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.41597250 |
| 65 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41534266 |
| 66 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.41486285 |
| 67 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.37809357 |
| 68 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37134949 |
| 69 | Melanoma_Homo sapiens_hsa05218 | 0.36595136 |
| 70 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.35136809 |
| 71 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.33428230 |
| 72 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.31259941 |
| 73 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.29813617 |
| 74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.27641842 |
| 75 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27413225 |
| 76 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.26231962 |
| 77 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.26214993 |
| 78 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.25332932 |
| 79 | Phototransduction_Homo sapiens_hsa04744 | 0.25222170 |
| 80 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.25189272 |
| 81 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25106333 |
| 82 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.22976859 |
| 83 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.22308895 |
| 84 | HTLV-I infection_Homo sapiens_hsa05166 | 0.21077578 |
| 85 | Prostate cancer_Homo sapiens_hsa05215 | 0.19640788 |
| 86 | Other glycan degradation_Homo sapiens_hsa00511 | 0.19157084 |
| 87 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.18645266 |
| 88 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.17961059 |
| 89 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.16567511 |
| 90 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.15812849 |
| 91 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.15006483 |
| 92 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.14330385 |
| 93 | Hepatitis B_Homo sapiens_hsa05161 | 0.13060549 |
| 94 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.11447013 |
| 95 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.11239429 |
| 96 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.11218353 |
| 97 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10372092 |
| 98 | Insulin resistance_Homo sapiens_hsa04931 | 0.08272208 |
| 99 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.06768183 |
| 100 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.05765061 |

