

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | germinal center formation (GO:0002467) | 5.46547861 |
| 2 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.93441499 |
| 3 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.93441499 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.51999088 |
| 5 | hepatocyte apoptotic process (GO:0097284) | 4.48260293 |
| 6 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.44421039 |
| 7 | histone H3-K4 trimethylation (GO:0080182) | 4.38534433 |
| 8 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.28549322 |
| 9 | growth hormone receptor signaling pathway (GO:0060396) | 4.26248032 |
| 10 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.25266920 |
| 11 | negative regulation of B cell mediated immunity (GO:0002713) | 4.00367224 |
| 12 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 4.00367224 |
| 13 | cellular response to ethanol (GO:0071361) | 3.97414639 |
| 14 | myeloid leukocyte mediated immunity (GO:0002444) | 3.93528379 |
| 15 | neutrophil activation involved in immune response (GO:0002283) | 3.91836323 |
| 16 | cellular extravasation (GO:0045123) | 3.90469627 |
| 17 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.88419481 |
| 18 | positive regulation of granulocyte differentiation (GO:0030854) | 3.87719614 |
| 19 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.85006600 |
| 20 | protein K11-linked deubiquitination (GO:0035871) | 3.77940070 |
| 21 | cellular response to growth hormone stimulus (GO:0071378) | 3.77393029 |
| 22 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.74186059 |
| 23 | regulation of memory T cell differentiation (GO:0043380) | 3.71887453 |
| 24 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.69927516 |
| 25 | regulation of germinal center formation (GO:0002634) | 3.68779585 |
| 26 | positive regulation of developmental pigmentation (GO:0048087) | 3.66621489 |
| 27 | protein K48-linked deubiquitination (GO:0071108) | 3.65013221 |
| 28 | detection of molecule of bacterial origin (GO:0032490) | 3.61378055 |
| 29 | negative regulation of Rho protein signal transduction (GO:0035024) | 3.58306751 |
| 30 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.50337363 |
| 31 | regulation of hypersensitivity (GO:0002883) | 3.47885426 |
| 32 | definitive hemopoiesis (GO:0060216) | 3.45110588 |
| 33 | histone H3-K36 demethylation (GO:0070544) | 3.44927547 |
| 34 | B cell receptor signaling pathway (GO:0050853) | 3.42286889 |
| 35 | peptidyl-lysine trimethylation (GO:0018023) | 3.40191847 |
| 36 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.38786971 |
| 37 | regulation of pigment cell differentiation (GO:0050932) | 3.35484484 |
| 38 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.33829204 |
| 39 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.33829204 |
| 40 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.33829204 |
| 41 | necrotic cell death (GO:0070265) | 3.31028328 |
| 42 | negative T cell selection (GO:0043383) | 3.30874882 |
| 43 | protein K63-linked deubiquitination (GO:0070536) | 3.26595554 |
| 44 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.25241141 |
| 45 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.20107694 |
| 46 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.18798884 |
| 47 | regulation of gamma-delta T cell activation (GO:0046643) | 3.17836551 |
| 48 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.15577781 |
| 49 | negative thymic T cell selection (GO:0045060) | 3.12001577 |
| 50 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.10682859 |
| 51 | peptidyl-lysine methylation (GO:0018022) | 3.10264662 |
| 52 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.10078031 |
| 53 | neutrophil mediated immunity (GO:0002446) | 3.02446070 |
| 54 | positive regulation by symbiont of host defense response (GO:0052509) | 3.00928322 |
| 55 | modulation by symbiont of host defense response (GO:0052031) | 3.00928322 |
| 56 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.00928322 |
| 57 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.00928322 |
| 58 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.00928322 |
| 59 | modulation by symbiont of host immune response (GO:0052553) | 3.00928322 |
| 60 | embryonic process involved in female pregnancy (GO:0060136) | 3.00926962 |
| 61 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.99293257 |
| 62 | cell wall macromolecule catabolic process (GO:0016998) | 2.99252630 |
| 63 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.98276091 |
| 64 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.97832578 |
| 65 | negative regulation of cell killing (GO:0031342) | 2.97832578 |
| 66 | negative regulation of type 2 immune response (GO:0002829) | 2.96852664 |
| 67 | corticosteroid receptor signaling pathway (GO:0031958) | 2.95775239 |
| 68 | histone H3-K4 methylation (GO:0051568) | 2.95509362 |
| 69 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.95408738 |
| 70 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.93559244 |
| 71 | myeloid cell activation involved in immune response (GO:0002275) | 2.90197521 |
| 72 | macrophage activation (GO:0042116) | 2.90087376 |
| 73 | macrophage activation involved in immune response (GO:0002281) | 2.89861490 |
| 74 | regulation of establishment of cell polarity (GO:2000114) | 2.89390821 |
| 75 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.89290854 |
| 76 | neutrophil activation (GO:0042119) | 2.88578848 |
| 77 | negative regulation of interleukin-12 production (GO:0032695) | 2.88431388 |
| 78 | regulation of viral entry into host cell (GO:0046596) | 2.86187783 |
| 79 | programmed necrotic cell death (GO:0097300) | 2.86035920 |
| 80 | T cell migration (GO:0072678) | 2.82565610 |
| 81 | innate immune response in mucosa (GO:0002227) | 2.81805899 |
| 82 | positive T cell selection (GO:0043368) | 2.81259897 |
| 83 | phospholipid translocation (GO:0045332) | 2.81142004 |
| 84 | lipid translocation (GO:0034204) | 2.81142004 |
| 85 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.80656140 |
| 86 | negative regulation of DNA recombination (GO:0045910) | 2.77472596 |
| 87 | pericardium development (GO:0060039) | 2.77383215 |
| 88 | iron ion import (GO:0097286) | 2.75829050 |
| 89 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.73561222 |
| 90 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.72550929 |
| 91 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.71944299 |
| 92 | microglial cell activation (GO:0001774) | 2.71106057 |
| 93 | negative regulation of viral entry into host cell (GO:0046597) | 2.70801837 |
| 94 | detection of external biotic stimulus (GO:0098581) | 2.70642038 |
| 95 | negative regulation of DNA repair (GO:0045738) | 2.69472160 |
| 96 | negative regulation of B cell proliferation (GO:0030889) | 2.66281204 |
| 97 | histone mRNA catabolic process (GO:0071044) | 2.63767976 |
| 98 | oocyte development (GO:0048599) | 2.62402283 |
| 99 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.61417174 |
| 100 | natural killer cell activation involved in immune response (GO:0002323) | 2.60042842 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.65798570 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.15126593 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.09573106 |
| 4 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 3.27131009 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.17148797 |
| 6 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.09590827 |
| 7 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.70144042 |
| 8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.50773009 |
| 9 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.40972481 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.35907336 |
| 11 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.35011296 |
| 12 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.30864966 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.29357912 |
| 14 | MYB_26560356_Chip-Seq_TH2_Human | 2.27322868 |
| 15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.23024695 |
| 16 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.20043921 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.17471367 |
| 18 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.13391115 |
| 19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.10136816 |
| 20 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.07892423 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.04243811 |
| 22 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.99372311 |
| 23 | TP53_16413492_ChIP-PET_HCT116_Human | 1.94974462 |
| 24 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.93193806 |
| 25 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.91550088 |
| 26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.91294857 |
| 27 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.88970121 |
| 28 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.83871269 |
| 29 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.81360650 |
| 30 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.80346039 |
| 31 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.76170129 |
| 32 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.75292764 |
| 33 | SPI1_23127762_ChIP-Seq_K562_Human | 1.70617383 |
| 34 | MYB_26560356_Chip-Seq_TH1_Human | 1.68151546 |
| 35 | GATA3_26560356_Chip-Seq_TH2_Human | 1.67539236 |
| 36 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.65044578 |
| 37 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.60332611 |
| 38 | GATA1_22025678_ChIP-Seq_K562_Human | 1.56278920 |
| 39 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.54388738 |
| 40 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.53798019 |
| 41 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.53332732 |
| 42 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.53320187 |
| 43 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.53143956 |
| 44 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.51475541 |
| 45 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.49846923 |
| 46 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.46668151 |
| 47 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.44914993 |
| 48 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.43129258 |
| 49 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40677981 |
| 50 | GATA1_19941826_ChIP-Seq_K562_Human | 1.35913624 |
| 51 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.35886593 |
| 52 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.35497356 |
| 53 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.34132032 |
| 54 | MAF_26560356_Chip-Seq_TH1_Human | 1.31665490 |
| 55 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.25839417 |
| 56 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.23211819 |
| 57 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.19316918 |
| 58 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.17891528 |
| 59 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.16965497 |
| 60 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.15800386 |
| 61 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.14513769 |
| 62 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14513769 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.13508220 |
| 64 | GATA2_19941826_ChIP-Seq_K562_Human | 1.10679825 |
| 65 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.09674037 |
| 66 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09508589 |
| 67 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.09193943 |
| 68 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.08921944 |
| 69 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.08751270 |
| 70 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08602559 |
| 71 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.07350638 |
| 72 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.06352764 |
| 73 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.05970670 |
| 74 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05554516 |
| 75 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.04007572 |
| 76 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.01821194 |
| 77 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.01146820 |
| 78 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.98524570 |
| 79 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.97458354 |
| 80 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97419411 |
| 81 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.96894610 |
| 82 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.96528214 |
| 83 | EWS_26573619_Chip-Seq_HEK293_Human | 0.96324324 |
| 84 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.94795472 |
| 85 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.93826947 |
| 86 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.93764141 |
| 87 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.92874904 |
| 88 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.92581803 |
| 89 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.90331070 |
| 90 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.88950055 |
| 91 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.88848665 |
| 92 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88573375 |
| 93 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88573375 |
| 94 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.87683137 |
| 95 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.87683137 |
| 96 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.87404681 |
| 97 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.84908008 |
| 98 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.83985980 |
| 99 | STAT3_23295773_ChIP-Seq_U87_Human | 0.82845263 |
| 100 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.82844239 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 5.13312210 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.93699935 |
| 3 | MP0004381_abnormal_hair_follicle | 3.92391452 |
| 4 | MP0000569_abnormal_digit_pigmentation | 3.76096298 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.26601543 |
| 6 | MP0003763_abnormal_thymus_physiology | 3.02829434 |
| 7 | MP0005075_abnormal_melanosome_morpholog | 2.92931835 |
| 8 | MP0002166_altered_tumor_susceptibility | 2.82263657 |
| 9 | MP0000685_abnormal_immune_system | 2.46342608 |
| 10 | MP0001853_heart_inflammation | 2.44968811 |
| 11 | MP0001800_abnormal_humoral_immune | 2.33541167 |
| 12 | MP0002396_abnormal_hematopoietic_system | 2.29160031 |
| 13 | MP0003828_pulmonary_edema | 2.14831160 |
| 14 | MP0010352_gastrointestinal_tract_polyps | 1.98195222 |
| 15 | MP0002006_tumorigenesis | 1.97595906 |
| 16 | MP0005167_abnormal_blood-brain_barrier | 1.87333615 |
| 17 | MP0003724_increased_susceptibility_to | 1.81808201 |
| 18 | MP0002405_respiratory_system_inflammati | 1.81669232 |
| 19 | MP0006054_spinal_hemorrhage | 1.78063441 |
| 20 | MP0002419_abnormal_innate_immunity | 1.75888799 |
| 21 | MP0002452_abnormal_antigen_presenting | 1.73303300 |
| 22 | MP0002420_abnormal_adaptive_immunity | 1.69048334 |
| 23 | MP0004808_abnormal_hematopoietic_stem | 1.68907478 |
| 24 | MP0001819_abnormal_immune_cell | 1.65664787 |
| 25 | MP0002723_abnormal_immune_serum | 1.63822339 |
| 26 | MP0009785_altered_susceptibility_to | 1.62239024 |
| 27 | MP0003866_abnormal_defecation | 1.60722161 |
| 28 | MP0002398_abnormal_bone_marrow | 1.60323713 |
| 29 | MP0000716_abnormal_immune_system | 1.52225446 |
| 30 | MP0005310_abnormal_salivary_gland | 1.51991276 |
| 31 | MP0001790_abnormal_immune_system | 1.50654322 |
| 32 | MP0005387_immune_system_phenotype | 1.50654322 |
| 33 | MP0008961_abnormal_basal_metabolism | 1.49508141 |
| 34 | MP0000689_abnormal_spleen_morphology | 1.46299018 |
| 35 | MP0005025_abnormal_response_to | 1.44444309 |
| 36 | MP0003045_fibrosis | 1.44416600 |
| 37 | MP0000703_abnormal_thymus_morphology | 1.43375386 |
| 38 | MP0004947_skin_inflammation | 1.43256409 |
| 39 | MP0003436_decreased_susceptibility_to | 1.42227965 |
| 40 | MP0005000_abnormal_immune_tolerance | 1.40336707 |
| 41 | MP0003172_abnormal_lysosome_physiology | 1.37338303 |
| 42 | MP0002722_abnormal_immune_system | 1.36947290 |
| 43 | MP0000015_abnormal_ear_pigmentation | 1.33511499 |
| 44 | MP0000427_abnormal_hair_cycle | 1.33353357 |
| 45 | MP0005076_abnormal_cell_differentiation | 1.29358484 |
| 46 | MP0004147_increased_porphyrin_level | 1.29158055 |
| 47 | MP0003091_abnormal_cell_migration | 1.29118577 |
| 48 | MP0003300_gastrointestinal_ulcer | 1.28427912 |
| 49 | MP0003303_peritoneal_inflammation | 1.27369599 |
| 50 | MP0004130_abnormal_muscle_cell | 1.24374894 |
| 51 | MP0001873_stomach_inflammation | 1.24308758 |
| 52 | MP0003786_premature_aging | 1.21814110 |
| 53 | MP0002429_abnormal_blood_cell | 1.19736171 |
| 54 | MP0003195_calcinosis | 1.16486585 |
| 55 | MP0002009_preneoplasia | 1.16353817 |
| 56 | MP0005671_abnormal_response_to | 1.14322995 |
| 57 | MP0005174_abnormal_tail_pigmentation | 1.13634064 |
| 58 | MP0009764_decreased_sensitivity_to | 1.12113570 |
| 59 | MP0002254_reproductive_system_inflammat | 1.11201365 |
| 60 | MP0001545_abnormal_hematopoietic_system | 1.10655227 |
| 61 | MP0005397_hematopoietic_system_phenotyp | 1.10655227 |
| 62 | MP0006082_CNS_inflammation | 1.10455394 |
| 63 | MP0002148_abnormal_hypersensitivity_rea | 1.08800259 |
| 64 | MP0001845_abnormal_inflammatory_respons | 1.01641991 |
| 65 | MP0000647_abnormal_sebaceous_gland | 0.99046081 |
| 66 | MP0009115_abnormal_fat_cell | 0.98947603 |
| 67 | MP0004484_altered_response_of | 0.93156198 |
| 68 | MP0002168_other_aberrant_phenotype | 0.89748971 |
| 69 | MP0002638_abnormal_pupillary_reflex | 0.89203420 |
| 70 | MP0009333_abnormal_splenocyte_physiolog | 0.87707260 |
| 71 | MP0000371_diluted_coat_color | 0.87431214 |
| 72 | MP0008995_early_reproductive_senescence | 0.86291045 |
| 73 | MP0005464_abnormal_platelet_physiology | 0.85753417 |
| 74 | MP0003646_muscle_fatigue | 0.85749331 |
| 75 | MP0005266_abnormal_metabolism | 0.85618702 |
| 76 | MP0002019_abnormal_tumor_incidence | 0.85361023 |
| 77 | MP0002998_abnormal_bone_remodeling | 0.84286316 |
| 78 | MP0002277_abnormal_respiratory_mucosa | 0.84133122 |
| 79 | MP0002332_abnormal_exercise_endurance | 0.81872937 |
| 80 | MP0008260_abnormal_autophagy | 0.80469982 |
| 81 | MP0004883_abnormal_blood_vessel | 0.79916969 |
| 82 | MP0003656_abnormal_erythrocyte_physiolo | 0.76549851 |
| 83 | MP0000372_irregular_coat_pigmentation | 0.76443459 |
| 84 | MP0001851_eye_inflammation | 0.75993504 |
| 85 | MP0005220_abnormal_exocrine_pancreas | 0.74142893 |
| 86 | MP0010155_abnormal_intestine_physiology | 0.73214366 |
| 87 | MP0003221_abnormal_cardiomyocyte_apopto | 0.69639898 |
| 88 | MP0005376_homeostasis/metabolism_phenot | 0.68121297 |
| 89 | MP0009697_abnormal_copulation | 0.67997953 |
| 90 | MP0005621_abnormal_cell_physiology | 0.67833179 |
| 91 | MP0008875_abnormal_xenobiotic_pharmacok | 0.67548440 |
| 92 | MP0003984_embryonic_growth_retardation | 0.66997099 |
| 93 | MP0002088_abnormal_embryonic_growth/wei | 0.66642906 |
| 94 | MP0002928_abnormal_bile_duct | 0.66600447 |
| 95 | MP0001542_abnormal_bone_strength | 0.64533966 |
| 96 | MP0000249_abnormal_blood_vessel | 0.62475988 |
| 97 | MP0006035_abnormal_mitochondrial_morpho | 0.61112343 |
| 98 | MP0005164_abnormal_response_to | 0.60628598 |
| 99 | MP0003252_abnormal_bile_duct | 0.57829913 |
| 100 | MP0008873_increased_physiological_sensi | 0.57238272 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.91987463 |
| 2 | Abnormality of the fingertips (HP:0001211) | 6.30639541 |
| 3 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.34287895 |
| 4 | Abnormality of alanine metabolism (HP:0010916) | 4.34287895 |
| 5 | Hyperalaninemia (HP:0003348) | 4.34287895 |
| 6 | Prominent nose (HP:0000448) | 3.56551796 |
| 7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.53144208 |
| 8 | Abnormality of T cell number (HP:0011839) | 3.52975464 |
| 9 | T lymphocytopenia (HP:0005403) | 3.48847916 |
| 10 | Genetic anticipation (HP:0003743) | 3.31702481 |
| 11 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.29320861 |
| 12 | Mediastinal lymphadenopathy (HP:0100721) | 3.10324757 |
| 13 | Chronic hepatic failure (HP:0100626) | 3.07164978 |
| 14 | Amyloidosis (HP:0011034) | 3.05498432 |
| 15 | Clubbing of toes (HP:0100760) | 3.04859682 |
| 16 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.00542367 |
| 17 | Recurrent cutaneous fungal infections (HP:0011370) | 3.00542367 |
| 18 | Recurrent fungal infections (HP:0002841) | 3.00443964 |
| 19 | Large eyes (HP:0001090) | 2.97348449 |
| 20 | Recurrent bronchitis (HP:0002837) | 2.90307347 |
| 21 | Stomatitis (HP:0010280) | 2.85584537 |
| 22 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.80598153 |
| 23 | Clumsiness (HP:0002312) | 2.77637284 |
| 24 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.72919781 |
| 25 | IgA deficiency (HP:0002720) | 2.72347719 |
| 26 | Colitis (HP:0002583) | 2.60778143 |
| 27 | Abnormality of the peritoneum (HP:0002585) | 2.54663539 |
| 28 | Autoimmune hemolytic anemia (HP:0001890) | 2.54338909 |
| 29 | Recurrent bacterial skin infections (HP:0005406) | 2.52752783 |
| 30 | Fair hair (HP:0002286) | 2.52541193 |
| 31 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.49732249 |
| 32 | Birth length less than 3rd percentile (HP:0003561) | 2.49624530 |
| 33 | Optic neuritis (HP:0100653) | 2.44866838 |
| 34 | Retrobulbar optic neuritis (HP:0100654) | 2.44866838 |
| 35 | Chronic otitis media (HP:0000389) | 2.43776146 |
| 36 | Microcytic anemia (HP:0001935) | 2.43343123 |
| 37 | IgM deficiency (HP:0002850) | 2.43295776 |
| 38 | Macroglossia (HP:0000158) | 2.43243777 |
| 39 | Papillary thyroid carcinoma (HP:0002895) | 2.43067919 |
| 40 | Postural instability (HP:0002172) | 2.40547852 |
| 41 | Myositis (HP:0100614) | 2.39675141 |
| 42 | Abnormality of T cells (HP:0002843) | 2.39535894 |
| 43 | Orchitis (HP:0100796) | 2.36443468 |
| 44 | Hypochromic microcytic anemia (HP:0004840) | 2.36226281 |
| 45 | Widely spaced teeth (HP:0000687) | 2.33288680 |
| 46 | Narrow palate (HP:0000189) | 2.29490522 |
| 47 | Sparse lateral eyebrow (HP:0005338) | 2.28520195 |
| 48 | Slow saccadic eye movements (HP:0000514) | 2.28361280 |
| 49 | Acute myeloid leukemia (HP:0004808) | 2.27772573 |
| 50 | Autoimmune thrombocytopenia (HP:0001973) | 2.26920616 |
| 51 | Leukocytosis (HP:0001974) | 2.26014897 |
| 52 | Recurrent abscess formation (HP:0002722) | 2.25859674 |
| 53 | Long eyelashes (HP:0000527) | 2.24723627 |
| 54 | Eosinophilia (HP:0001880) | 2.23518168 |
| 55 | Encephalitis (HP:0002383) | 2.19546793 |
| 56 | Protruding tongue (HP:0010808) | 2.19423806 |
| 57 | Abnormal glucose tolerance (HP:0001952) | 2.16385827 |
| 58 | Submucous cleft hard palate (HP:0000176) | 2.15716370 |
| 59 | Eczematoid dermatitis (HP:0000976) | 2.14529021 |
| 60 | Meningitis (HP:0001287) | 2.13841918 |
| 61 | Gaze-evoked nystagmus (HP:0000640) | 2.11228209 |
| 62 | Subacute progressive viral hepatitis (HP:0006572) | 2.07772915 |
| 63 | Spontaneous hematomas (HP:0007420) | 2.06060275 |
| 64 | Bicuspid aortic valve (HP:0001647) | 2.05256191 |
| 65 | Recurrent viral infections (HP:0004429) | 2.04115057 |
| 66 | Generalized hypopigmentation of hair (HP:0011358) | 2.03556194 |
| 67 | Basal ganglia calcification (HP:0002135) | 2.03381717 |
| 68 | Vasculitis (HP:0002633) | 2.02949923 |
| 69 | Lip pit (HP:0100267) | 2.00949097 |
| 70 | Chest pain (HP:0100749) | 2.00572724 |
| 71 | Increased cerebral lipofuscin (HP:0011813) | 1.99484612 |
| 72 | Abnormality of eosinophils (HP:0001879) | 1.99353803 |
| 73 | Abnormal hair whorl (HP:0010721) | 1.99043685 |
| 74 | Micronodular cirrhosis (HP:0001413) | 1.98718038 |
| 75 | Tubulointerstitial nephritis (HP:0001970) | 1.95406300 |
| 76 | Facial diplegia (HP:0001349) | 1.93744539 |
| 77 | Recurrent skin infections (HP:0001581) | 1.92686118 |
| 78 | Viral hepatitis (HP:0006562) | 1.92647683 |
| 79 | Hematochezia (HP:0002573) | 1.92521299 |
| 80 | Febrile seizures (HP:0002373) | 1.91002617 |
| 81 | Hypoplastic iliac wings (HP:0002866) | 1.90317407 |
| 82 | Abnormality of T cell physiology (HP:0011840) | 1.89636202 |
| 83 | Inflammation of the large intestine (HP:0002037) | 1.89090640 |
| 84 | Abnormality of the pleura (HP:0002103) | 1.89031689 |
| 85 | Granulocytopenia (HP:0001913) | 1.88828186 |
| 86 | Neonatal hypoglycemia (HP:0001998) | 1.83810118 |
| 87 | Fatigue (HP:0012378) | 1.83354011 |
| 88 | Abnormality of the columella (HP:0009929) | 1.82457484 |
| 89 | Ileus (HP:0002595) | 1.80488242 |
| 90 | Chronic diarrhea (HP:0002028) | 1.80218943 |
| 91 | Abnormal spermatogenesis (HP:0008669) | 1.79911481 |
| 92 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.78735154 |
| 93 | Gastrointestinal infarctions (HP:0005244) | 1.77946960 |
| 94 | Acute lymphatic leukemia (HP:0006721) | 1.76539266 |
| 95 | Hyperventilation (HP:0002883) | 1.76427801 |
| 96 | Thyroiditis (HP:0100646) | 1.76273942 |
| 97 | Stomach cancer (HP:0012126) | 1.76029559 |
| 98 | Short chin (HP:0000331) | 1.75398873 |
| 99 | Atonic seizures (HP:0010819) | 1.73254321 |
| 100 | Arterial thrombosis (HP:0004420) | 1.71763307 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.21120347 |
| 2 | AKT3 | 4.76122432 |
| 3 | ACVR1B | 2.76935216 |
| 4 | PIK3CG | 2.16298233 |
| 5 | BLK | 2.11851344 |
| 6 | CAMK1D | 2.10922466 |
| 7 | BRD4 | 2.09219520 |
| 8 | NLK | 2.01221256 |
| 9 | MAP3K6 | 1.97637886 |
| 10 | CDK12 | 1.95763642 |
| 11 | CHUK | 1.93794005 |
| 12 | IKBKE | 1.85121145 |
| 13 | TXK | 1.76672991 |
| 14 | MARK3 | 1.75170277 |
| 15 | MELK | 1.73840335 |
| 16 | MAP2K3 | 1.73181554 |
| 17 | MKNK2 | 1.70004412 |
| 18 | IRAK1 | 1.63432593 |
| 19 | MAP3K14 | 1.61986709 |
| 20 | TAOK3 | 1.59267801 |
| 21 | MAP3K2 | 1.58430764 |
| 22 | IKBKB | 1.54039825 |
| 23 | MAP3K5 | 1.48224012 |
| 24 | TRPM7 | 1.45066126 |
| 25 | MAP4K1 | 1.43586361 |
| 26 | TEC | 1.40360903 |
| 27 | BTK | 1.39608461 |
| 28 | PIM1 | 1.36195292 |
| 29 | SGK2 | 1.33068558 |
| 30 | WNK1 | 1.32716642 |
| 31 | RIPK4 | 1.28149228 |
| 32 | TYK2 | 1.23699084 |
| 33 | CAMK1G | 1.18941854 |
| 34 | CAMKK2 | 1.16011381 |
| 35 | BMPR1B | 1.13930514 |
| 36 | MAP3K13 | 1.13051690 |
| 37 | JAK1 | 1.12408494 |
| 38 | SYK | 1.09671487 |
| 39 | PIK3CA | 1.02849640 |
| 40 | OXSR1 | 1.02075718 |
| 41 | FGFR3 | 1.02063943 |
| 42 | MAPK11 | 1.00769583 |
| 43 | ZAP70 | 0.99914894 |
| 44 | CSK | 0.99400693 |
| 45 | STK4 | 0.98300200 |
| 46 | NUAK1 | 0.94655113 |
| 47 | SGK3 | 0.89438210 |
| 48 | LATS1 | 0.89351549 |
| 49 | HCK | 0.88248598 |
| 50 | JAK2 | 0.86026963 |
| 51 | ITK | 0.85279342 |
| 52 | MAP3K7 | 0.82849647 |
| 53 | CAMK4 | 0.80440950 |
| 54 | PTK2B | 0.77962370 |
| 55 | IRAK4 | 0.77662142 |
| 56 | CDK6 | 0.75810570 |
| 57 | JAK3 | 0.75553939 |
| 58 | STK11 | 0.73819282 |
| 59 | IRAK2 | 0.70022218 |
| 60 | CAMK1 | 0.67327308 |
| 61 | RAF1 | 0.66696509 |
| 62 | RPS6KB2 | 0.66263970 |
| 63 | LCK | 0.65739665 |
| 64 | MARK2 | 0.65070734 |
| 65 | FES | 0.63505209 |
| 66 | PKN2 | 0.62282624 |
| 67 | GRK6 | 0.61297423 |
| 68 | SIK2 | 0.58844374 |
| 69 | RPS6KA5 | 0.57956332 |
| 70 | LYN | 0.56460372 |
| 71 | ZAK | 0.55706807 |
| 72 | TLK1 | 0.55390989 |
| 73 | SGK223 | 0.53066428 |
| 74 | SGK494 | 0.53066428 |
| 75 | PDK2 | 0.53049674 |
| 76 | PDK1 | 0.51420252 |
| 77 | PDGFRB | 0.50500114 |
| 78 | BMPR2 | 0.49717479 |
| 79 | NEK6 | 0.49363406 |
| 80 | FER | 0.49055764 |
| 81 | PRKAA1 | 0.48643168 |
| 82 | ATR | 0.48462965 |
| 83 | PRKAA2 | 0.47320423 |
| 84 | MKNK1 | 0.46653288 |
| 85 | KSR1 | 0.46136851 |
| 86 | PRKCQ | 0.46049392 |
| 87 | MAP3K1 | 0.45608491 |
| 88 | YES1 | 0.43732744 |
| 89 | EPHB1 | 0.43535327 |
| 90 | EGFR | 0.42717616 |
| 91 | BRSK2 | 0.41246129 |
| 92 | NEK9 | 0.40752132 |
| 93 | MAP4K2 | 0.39951246 |
| 94 | CSNK1A1L | 0.38310394 |
| 95 | DYRK1A | 0.37335848 |
| 96 | RET | 0.36883755 |
| 97 | HIPK2 | 0.36864658 |
| 98 | INSRR | 0.36733719 |
| 99 | STK10 | 0.36588170 |
| 100 | SGK1 | 0.36533140 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 3.92811984 |
| 2 | Viral carcinogenesis_Homo sapiens_hsa05203 | 2.48714491 |
| 3 | Alcoholism_Homo sapiens_hsa05034 | 2.34993214 |
| 4 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.12626794 |
| 5 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.08725053 |
| 6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.99220831 |
| 7 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.77852639 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.75387676 |
| 9 | Leishmaniasis_Homo sapiens_hsa05140 | 1.71970697 |
| 10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.71560102 |
| 11 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.69177229 |
| 12 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.68858233 |
| 13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.65434012 |
| 14 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.62577949 |
| 15 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.55489723 |
| 16 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.54898972 |
| 17 | Measles_Homo sapiens_hsa05162 | 1.54331406 |
| 18 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.52205152 |
| 19 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.51884607 |
| 20 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.49592475 |
| 21 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.48603851 |
| 22 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.47706954 |
| 23 | Allograft rejection_Homo sapiens_hsa05330 | 1.46215898 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.44508614 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.42482283 |
| 26 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.42361158 |
| 27 | Tuberculosis_Homo sapiens_hsa05152 | 1.42309174 |
| 28 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.36450115 |
| 29 | Influenza A_Homo sapiens_hsa05164 | 1.36027452 |
| 30 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.33832823 |
| 31 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.32182063 |
| 32 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.29732521 |
| 33 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.29221534 |
| 34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.26874605 |
| 35 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.22055253 |
| 36 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.21810238 |
| 37 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.21274912 |
| 38 | Hepatitis B_Homo sapiens_hsa05161 | 1.20859090 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.20265939 |
| 40 | Legionellosis_Homo sapiens_hsa05134 | 1.18208796 |
| 41 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.17330432 |
| 42 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.14982296 |
| 43 | Lysine degradation_Homo sapiens_hsa00310 | 1.12758047 |
| 44 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.11628520 |
| 45 | Circadian rhythm_Homo sapiens_hsa04710 | 1.08469742 |
| 46 | Platelet activation_Homo sapiens_hsa04611 | 1.08413678 |
| 47 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.08029219 |
| 48 | Endometrial cancer_Homo sapiens_hsa05213 | 1.06722888 |
| 49 | Colorectal cancer_Homo sapiens_hsa05210 | 1.06599769 |
| 50 | Apoptosis_Homo sapiens_hsa04210 | 1.04098510 |
| 51 | Hepatitis C_Homo sapiens_hsa05160 | 1.03779982 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.02264744 |
| 53 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.00811745 |
| 54 | Prostate cancer_Homo sapiens_hsa05215 | 0.99016471 |
| 55 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.88408459 |
| 56 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.87578877 |
| 57 | ABC transporters_Homo sapiens_hsa02010 | 0.85481031 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.85359365 |
| 59 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84454971 |
| 60 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.82469630 |
| 61 | Malaria_Homo sapiens_hsa05144 | 0.81940312 |
| 62 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.78929516 |
| 63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.78732534 |
| 64 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.78198213 |
| 65 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.77169974 |
| 66 | Taste transduction_Homo sapiens_hsa04742 | 0.75453039 |
| 67 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.74962725 |
| 68 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.72194032 |
| 69 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.70441886 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.69878050 |
| 71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.65356045 |
| 72 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.65329985 |
| 73 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.65109754 |
| 74 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.64685212 |
| 75 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.64563940 |
| 76 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.63763321 |
| 77 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.62615135 |
| 78 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.60534887 |
| 79 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.59429597 |
| 80 | Insulin resistance_Homo sapiens_hsa04931 | 0.59394451 |
| 81 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.58038105 |
| 82 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.57744132 |
| 83 | HTLV-I infection_Homo sapiens_hsa05166 | 0.55000613 |
| 84 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.53271949 |
| 85 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.52021518 |
| 86 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.51518400 |
| 87 | RNA polymerase_Homo sapiens_hsa03020 | 0.49879116 |
| 88 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.49299941 |
| 89 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.48884234 |
| 90 | Homologous recombination_Homo sapiens_hsa03440 | 0.48493582 |
| 91 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48080889 |
| 92 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.47503032 |
| 93 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.43257451 |
| 94 | Thyroid cancer_Homo sapiens_hsa05216 | 0.43253110 |
| 95 | Asthma_Homo sapiens_hsa05310 | 0.42567798 |
| 96 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.42373883 |
| 97 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.42218131 |
| 98 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.39079797 |
| 99 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.38963825 |
| 100 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.38036237 |

