

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | desmosome organization (GO:0002934) | 6.66605125 |
| 2 | Golgi transport vesicle coating (GO:0048200) | 5.17738113 |
| 3 | COPI coating of Golgi vesicle (GO:0048205) | 5.17738113 |
| 4 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.08917483 |
| 5 | protein maturation by protein folding (GO:0022417) | 4.90630199 |
| 6 | hemidesmosome assembly (GO:0031581) | 4.82190156 |
| 7 | artery smooth muscle contraction (GO:0014824) | 4.73057287 |
| 8 | establishment of integrated proviral latency (GO:0075713) | 4.35555898 |
| 9 | positive regulation of epidermal cell differentiation (GO:0045606) | 4.26849526 |
| 10 | interferon-gamma secretion (GO:0072643) | 4.26183941 |
| 11 | establishment of viral latency (GO:0019043) | 4.21037129 |
| 12 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.14487012 |
| 13 | tonic smooth muscle contraction (GO:0014820) | 4.01126940 |
| 14 | nuclear envelope reassembly (GO:0031468) | 3.96848253 |
| 15 | mitotic nuclear envelope reassembly (GO:0007084) | 3.96848253 |
| 16 | prostaglandin biosynthetic process (GO:0001516) | 3.91551759 |
| 17 | prostanoid biosynthetic process (GO:0046457) | 3.91551759 |
| 18 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 3.89727787 |
| 19 | positive regulation of actin filament depolymerization (GO:0030836) | 3.84332242 |
| 20 | hepatocyte apoptotic process (GO:0097284) | 3.80929434 |
| 21 | regulation of water loss via skin (GO:0033561) | 3.78549193 |
| 22 | xenobiotic catabolic process (GO:0042178) | 3.68803481 |
| 23 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.62179545 |
| 24 | regulation of metalloenzyme activity (GO:0048552) | 3.58114813 |
| 25 | proteasome assembly (GO:0043248) | 3.57518217 |
| 26 | GDP-mannose metabolic process (GO:0019673) | 3.52334744 |
| 27 | establishment of skin barrier (GO:0061436) | 3.49135156 |
| 28 | protein retention in ER lumen (GO:0006621) | 3.48228456 |
| 29 | membrane raft organization (GO:0031579) | 3.44175418 |
| 30 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.42122378 |
| 31 | NADH metabolic process (GO:0006734) | 3.36815417 |
| 32 | daunorubicin metabolic process (GO:0044597) | 3.36811189 |
| 33 | polyketide metabolic process (GO:0030638) | 3.36811189 |
| 34 | doxorubicin metabolic process (GO:0044598) | 3.36811189 |
| 35 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.27854727 |
| 36 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.27496354 |
| 37 | membrane budding (GO:0006900) | 3.26133799 |
| 38 | muscle cell migration (GO:0014812) | 3.25321778 |
| 39 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 3.23377625 |
| 40 | galactose catabolic process (GO:0019388) | 3.18767152 |
| 41 | glucose 6-phosphate metabolic process (GO:0051156) | 3.17175794 |
| 42 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.16378192 |
| 43 | prostanoid metabolic process (GO:0006692) | 3.14512379 |
| 44 | prostaglandin metabolic process (GO:0006693) | 3.14512379 |
| 45 | regulation of cell proliferation involved in kidney development (GO:1901722) | 3.13970698 |
| 46 | keratinocyte development (GO:0003334) | 3.13802824 |
| 47 | negative regulation of kidney development (GO:0090185) | 3.10648006 |
| 48 | positive regulation of pseudopodium assembly (GO:0031274) | 3.10262577 |
| 49 | positive regulation of epidermis development (GO:0045684) | 3.08350270 |
| 50 | ribosome assembly (GO:0042255) | 3.05109199 |
| 51 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.02384824 |
| 52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.00025116 |
| 53 | mesonephros development (GO:0001823) | 2.99139823 |
| 54 | pentose-phosphate shunt (GO:0006098) | 2.95468254 |
| 55 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.93930633 |
| 56 | glucose catabolic process (GO:0006007) | 2.93334207 |
| 57 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.92632780 |
| 58 | multicellular organismal water homeostasis (GO:0050891) | 2.90439317 |
| 59 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 2.90180254 |
| 60 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.87401503 |
| 61 | macrophage chemotaxis (GO:0048246) | 2.85564764 |
| 62 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.85512376 |
| 63 | hepatocyte differentiation (GO:0070365) | 2.85098698 |
| 64 | inositol phosphate-mediated signaling (GO:0048016) | 2.83673129 |
| 65 | diterpenoid biosynthetic process (GO:0016102) | 2.81027430 |
| 66 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.80390822 |
| 67 | NADPH regeneration (GO:0006740) | 2.79322607 |
| 68 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.79129041 |
| 69 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.79129041 |
| 70 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.78799257 |
| 71 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.78050958 |
| 72 | positive regulation of keratinocyte differentiation (GO:0045618) | 2.76641260 |
| 73 | type B pancreatic cell proliferation (GO:0044342) | 2.76610113 |
| 74 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.75810440 |
| 75 | negative regulation of ligase activity (GO:0051352) | 2.75810440 |
| 76 | cell differentiation involved in embryonic placenta development (GO:0060706) | 2.74504198 |
| 77 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.73701403 |
| 78 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.73701403 |
| 79 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.73701403 |
| 80 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.73237407 |
| 81 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.73237407 |
| 82 | galactose metabolic process (GO:0006012) | 2.71813464 |
| 83 | regulation of pseudopodium assembly (GO:0031272) | 2.69658773 |
| 84 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.68346108 |
| 85 | endothelial tube morphogenesis (GO:0061154) | 2.68259784 |
| 86 | morphogenesis of an endothelium (GO:0003159) | 2.68259784 |
| 87 | embryonic skeletal joint morphogenesis (GO:0060272) | 2.66033490 |
| 88 | proline biosynthetic process (GO:0006561) | 2.65864841 |
| 89 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.65221399 |
| 90 | epithelial cell-cell adhesion (GO:0090136) | 2.63737542 |
| 91 | establishment of protein localization to plasma membrane (GO:0090002) | 2.60398495 |
| 92 | actin filament depolymerization (GO:0030042) | 2.59377741 |
| 93 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.58943881 |
| 94 | intestinal epithelial cell development (GO:0060576) | 2.58678827 |
| 95 | negative regulation of cell fate specification (GO:0009996) | 2.58425071 |
| 96 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.58132253 |
| 97 | regulation of cardioblast differentiation (GO:0051890) | 2.57287606 |
| 98 | barbed-end actin filament capping (GO:0051016) | 2.54513922 |
| 99 | extracellular fibril organization (GO:0043206) | 2.53380395 |
| 100 | cellular copper ion homeostasis (GO:0006878) | 2.51692540 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 5.02777778 |
| 2 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 4.55976134 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.45669674 |
| 4 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 3.30618237 |
| 5 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.77099396 |
| 6 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.76301792 |
| 7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.68863355 |
| 8 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.64379738 |
| 9 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.63698055 |
| 10 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.45521259 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.18213479 |
| 12 | RACK7_27058665_Chip-Seq_MCF-7_Human | 2.18074702 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.13529207 |
| 14 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 2.08560766 |
| 15 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.05432670 |
| 16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.98453681 |
| 17 | ATF3_27146783_Chip-Seq_COLON_Human | 1.97331926 |
| 18 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.97084067 |
| 19 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.97084067 |
| 20 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.91336823 |
| 21 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.91102156 |
| 22 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.85222630 |
| 23 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.83122580 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.77095455 |
| 25 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.75778477 |
| 26 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.75755507 |
| 27 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.75305989 |
| 28 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.69544029 |
| 29 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.67475800 |
| 30 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.64019075 |
| 31 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.63136391 |
| 32 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.61626974 |
| 33 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61440372 |
| 34 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.61111728 |
| 35 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.59519656 |
| 36 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.57541112 |
| 37 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.56906579 |
| 38 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.55724773 |
| 39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.54794258 |
| 40 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.54353296 |
| 41 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.53470185 |
| 42 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.52821279 |
| 43 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.51651169 |
| 44 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.51048813 |
| 45 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.48270349 |
| 46 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.48240967 |
| 47 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.47205533 |
| 48 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.47041541 |
| 49 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.45724994 |
| 50 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.44451058 |
| 51 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.38744955 |
| 52 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.37235517 |
| 53 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.36688854 |
| 54 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.35974816 |
| 55 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.35876529 |
| 56 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.33786624 |
| 57 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.33217450 |
| 58 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.32350043 |
| 59 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.31589609 |
| 60 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.30332802 |
| 61 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.30068236 |
| 62 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.29958787 |
| 63 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.28523404 |
| 64 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.28272987 |
| 65 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.25913764 |
| 66 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.25865883 |
| 67 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.24293064 |
| 68 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.23393237 |
| 69 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.22382757 |
| 70 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.21209700 |
| 71 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20771890 |
| 72 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.19939131 |
| 73 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.19641666 |
| 74 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.19508480 |
| 75 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.16727365 |
| 76 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.16325237 |
| 77 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.14927006 |
| 78 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.14366584 |
| 79 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.12690730 |
| 80 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.12458580 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.12399365 |
| 82 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.11472136 |
| 83 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.11274621 |
| 84 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.10285687 |
| 85 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.09101688 |
| 86 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.08990557 |
| 87 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.08635906 |
| 88 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.07593358 |
| 89 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.07554700 |
| 90 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.07399799 |
| 91 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.06729251 |
| 92 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.05803797 |
| 93 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.00991708 |
| 94 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.00630046 |
| 95 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.00400555 |
| 96 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.00236364 |
| 97 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.98881536 |
| 98 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.98873482 |
| 99 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98648611 |
| 100 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.97809580 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010234_abnormal_vibrissa_follicle | 5.34265697 |
| 2 | MP0004264_abnormal_extraembryonic_tissu | 4.55946772 |
| 3 | MP0002796_impaired_skin_barrier | 3.76283218 |
| 4 | MP0003191_abnormal_cellular_cholesterol | 2.86217329 |
| 5 | MP0005501_abnormal_skin_physiology | 2.75170582 |
| 6 | MP0003566_abnormal_cell_adhesion | 2.53577250 |
| 7 | MP0003806_abnormal_nucleotide_metabolis | 2.52532982 |
| 8 | MP0005360_urolithiasis | 2.50462519 |
| 9 | MP0005083_abnormal_biliary_tract | 2.46638791 |
| 10 | MP0003315_abnormal_perineum_morphology | 2.31122685 |
| 11 | MP0000537_abnormal_urethra_morphology | 2.14054222 |
| 12 | MP0009780_abnormal_chondrocyte_physiolo | 2.10487507 |
| 13 | MP0001216_abnormal_epidermal_layer | 2.10406933 |
| 14 | MP0000762_abnormal_tongue_morphology | 2.08865170 |
| 15 | MP0000467_abnormal_esophagus_morphology | 2.06116247 |
| 16 | MP0002060_abnormal_skin_morphology | 2.05821141 |
| 17 | MP0002098_abnormal_vibrissa_morphology | 2.05070292 |
| 18 | MP0008260_abnormal_autophagy | 2.04446069 |
| 19 | MP0010678_abnormal_skin_adnexa | 2.04054558 |
| 20 | MP0003693_abnormal_embryo_hatching | 2.04053830 |
| 21 | MP0009840_abnormal_foam_cell | 1.98614041 |
| 22 | MP0010030_abnormal_orbit_morphology | 1.98521328 |
| 23 | MP0003941_abnormal_skin_development | 1.95147546 |
| 24 | MP0002877_abnormal_melanocyte_morpholog | 1.90925959 |
| 25 | MP0003123_paternal_imprinting | 1.90556409 |
| 26 | MP0001666_abnormal_nutrient_absorption | 1.88997437 |
| 27 | MP0009053_abnormal_anal_canal | 1.88684311 |
| 28 | MP0005257_abnormal_intraocular_pressure | 1.79542406 |
| 29 | MP0003453_abnormal_keratinocyte_physiol | 1.75225197 |
| 30 | MP0004272_abnormal_basement_membrane | 1.73404665 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.70872403 |
| 32 | MP0000579_abnormal_nail_morphology | 1.70578810 |
| 33 | MP0010352_gastrointestinal_tract_polyps | 1.66259343 |
| 34 | MP0005451_abnormal_body_composition | 1.64536930 |
| 35 | MP0010771_integument_phenotype | 1.63639512 |
| 36 | MP0003950_abnormal_plasma_membrane | 1.57444307 |
| 37 | MP0000516_abnormal_urinary_system | 1.55500638 |
| 38 | MP0005367_renal/urinary_system_phenotyp | 1.55500638 |
| 39 | MP0004957_abnormal_blastocyst_morpholog | 1.46582860 |
| 40 | MP0000383_abnormal_hair_follicle | 1.46527411 |
| 41 | MP0000627_abnormal_mammary_gland | 1.42054313 |
| 42 | MP0000750_abnormal_muscle_regeneration | 1.39125714 |
| 43 | MP0004019_abnormal_vitamin_homeostasis | 1.36197345 |
| 44 | MP0003705_abnormal_hypodermis_morpholog | 1.32612149 |
| 45 | MP0000377_abnormal_hair_follicle | 1.31317781 |
| 46 | MP0005165_increased_susceptibility_to | 1.29700708 |
| 47 | MP0005023_abnormal_wound_healing | 1.25692382 |
| 48 | MP0005670_abnormal_white_adipose | 1.25572541 |
| 49 | MP0000647_abnormal_sebaceous_gland | 1.17459142 |
| 50 | MP0000858_altered_metastatic_potential | 1.13976986 |
| 51 | MP0003786_premature_aging | 1.13738751 |
| 52 | MP0001881_abnormal_mammary_gland | 1.10028423 |
| 53 | MP0005365_abnormal_bile_salt | 1.09235740 |
| 54 | MP0005058_abnormal_lysosome_morphology | 1.07141605 |
| 55 | MP0005330_cardiomyopathy | 1.06712328 |
| 56 | MP0000462_abnormal_digestive_system | 1.03281410 |
| 57 | MP0000566_synostosis | 1.02021033 |
| 58 | MP0000427_abnormal_hair_cycle | 0.99613245 |
| 59 | MP0008007_abnormal_cellular_replicative | 0.98062397 |
| 60 | MP0000751_myopathy | 0.96956509 |
| 61 | MP0000538_abnormal_urinary_bladder | 0.95606617 |
| 62 | MP0003638_abnormal_response/metabolism_ | 0.95371704 |
| 63 | MP0009931_abnormal_skin_appearance | 0.91934080 |
| 64 | MP0000490_abnormal_crypts_of | 0.91373127 |
| 65 | MP0004233_abnormal_muscle_weight | 0.89084587 |
| 66 | MP0000678_abnormal_parathyroid_gland | 0.88186652 |
| 67 | MP0003075_altered_response_to | 0.87409797 |
| 68 | MP0001243_abnormal_dermal_layer | 0.86469312 |
| 69 | MP0001849_ear_inflammation | 0.86186845 |
| 70 | MP0004782_abnormal_surfactant_physiolog | 0.84326862 |
| 71 | MP0000749_muscle_degeneration | 0.83699551 |
| 72 | MP0001727_abnormal_embryo_implantation | 0.81138488 |
| 73 | MP0009643_abnormal_urine_homeostasis | 0.80868206 |
| 74 | MP0001730_embryonic_growth_arrest | 0.80614327 |
| 75 | MP0001340_abnormal_eyelid_morphology | 0.79855879 |
| 76 | MP0000358_abnormal_cell_content/ | 0.76809819 |
| 77 | MP0001873_stomach_inflammation | 0.75799825 |
| 78 | MP0000534_abnormal_ureter_morphology | 0.74562524 |
| 79 | MP0002177_abnormal_outer_ear | 0.74458343 |
| 80 | MP0000477_abnormal_intestine_morphology | 0.74004977 |
| 81 | MP0003718_maternal_effect | 0.73568625 |
| 82 | MP0001765_abnormal_ion_homeostasis | 0.73490566 |
| 83 | MP0004185_abnormal_adipocyte_glucose | 0.71760983 |
| 84 | MP0002234_abnormal_pharynx_morphology | 0.71360892 |
| 85 | MP0003936_abnormal_reproductive_system | 0.70658800 |
| 86 | MP0000613_abnormal_salivary_gland | 0.70363754 |
| 87 | MP0008932_abnormal_embryonic_tissue | 0.69600772 |
| 88 | MP0001542_abnormal_bone_strength | 0.68713442 |
| 89 | MP0003077_abnormal_cell_cycle | 0.67955669 |
| 90 | MP0002080_prenatal_lethality | 0.67684123 |
| 91 | MP0005085_abnormal_gallbladder_physiolo | 0.66291729 |
| 92 | MP0001664_abnormal_digestion | 0.65714467 |
| 93 | MP0005408_hypopigmentation | 0.65159037 |
| 94 | MP0002653_abnormal_ependyma_morphology | 0.64971077 |
| 95 | MP0000350_abnormal_cell_proliferation | 0.64944960 |
| 96 | MP0005197_abnormal_uvea_morphology | 0.63264341 |
| 97 | MP0000343_altered_response_to | 0.62907389 |
| 98 | MP0003866_abnormal_defecation | 0.62268068 |
| 99 | MP0005166_decreased_susceptibility_to | 0.61919589 |
| 100 | MP0000367_abnormal_coat/_hair | 0.61717123 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Right ventricular cardiomyopathy (HP:0011663) | 5.21032033 |
| 2 | Vascular calcification (HP:0004934) | 4.30472327 |
| 3 | Abnormality of the distal phalanges of the toes (HP:0010182) | 4.03603921 |
| 4 | Distal lower limb muscle weakness (HP:0009053) | 3.96607885 |
| 5 | Pili torti (HP:0003777) | 3.74710030 |
| 6 | Cardiovascular calcification (HP:0011915) | 3.69986276 |
| 7 | Abnormal hair laboratory examination (HP:0003328) | 3.51738263 |
| 8 | Short nail (HP:0001799) | 3.41217378 |
| 9 | Onycholysis (HP:0001806) | 3.37194507 |
| 10 | Sparse eyelashes (HP:0000653) | 3.32535358 |
| 11 | Milia (HP:0001056) | 3.32113579 |
| 12 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.28235108 |
| 13 | Alopecia of scalp (HP:0002293) | 3.26343055 |
| 14 | Fragile nails (HP:0001808) | 3.21331772 |
| 15 | Microglossia (HP:0000171) | 3.19586183 |
| 16 | Micronodular cirrhosis (HP:0001413) | 3.04841286 |
| 17 | Upper limb muscle weakness (HP:0003484) | 2.94588163 |
| 18 | Adrenal hypoplasia (HP:0000835) | 2.91445407 |
| 19 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.88960228 |
| 20 | Plantar hyperkeratosis (HP:0007556) | 2.88262946 |
| 21 | Nail dystrophy (HP:0008404) | 2.86454777 |
| 22 | Glucose intolerance (HP:0000833) | 2.82427730 |
| 23 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.66335997 |
| 24 | Osteolytic defects of the hand bones (HP:0009699) | 2.66335997 |
| 25 | Abnormality of glycolysis (HP:0004366) | 2.66168567 |
| 26 | Atrophic scars (HP:0001075) | 2.61835977 |
| 27 | Abnormality of the umbilical cord (HP:0010881) | 2.61562940 |
| 28 | Selective tooth agenesis (HP:0001592) | 2.61036155 |
| 29 | Rough bone trabeculation (HP:0100670) | 2.60868746 |
| 30 | Distal lower limb amyotrophy (HP:0008944) | 2.59462612 |
| 31 | Thick nail (HP:0001805) | 2.54973036 |
| 32 | Axonal loss (HP:0003447) | 2.53448314 |
| 33 | Type I transferrin isoform profile (HP:0003642) | 2.52691832 |
| 34 | Increased serum pyruvate (HP:0003542) | 2.51673532 |
| 35 | Cholecystitis (HP:0001082) | 2.47834333 |
| 36 | Abnormal gallbladder physiology (HP:0012438) | 2.47834333 |
| 37 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.46926971 |
| 38 | Trismus (HP:0000211) | 2.45797612 |
| 39 | Delayed CNS myelination (HP:0002188) | 2.42992362 |
| 40 | Abnormalities of placenta or umbilical cord (HP:0001194) | 2.42565895 |
| 41 | Prolonged neonatal jaundice (HP:0006579) | 2.41380380 |
| 42 | Reduced antithrombin III activity (HP:0001976) | 2.38516449 |
| 43 | Vertebral compression fractures (HP:0002953) | 2.36416792 |
| 44 | Premature rupture of membranes (HP:0001788) | 2.36369965 |
| 45 | Entropion (HP:0000621) | 2.30728982 |
| 46 | Microretrognathia (HP:0000308) | 2.25038037 |
| 47 | Acanthosis nigricans (HP:0000956) | 2.22957323 |
| 48 | Septate vagina (HP:0001153) | 2.22532781 |
| 49 | Abnormal trabecular bone morphology (HP:0100671) | 2.22500297 |
| 50 | J-shaped sella turcica (HP:0002680) | 2.20649418 |
| 51 | Ridged nail (HP:0001807) | 2.20048634 |
| 52 | Abnormal glucose tolerance (HP:0001952) | 2.19869228 |
| 53 | Palpitations (HP:0001962) | 2.19836281 |
| 54 | Palmoplantar hyperkeratosis (HP:0000972) | 2.19201005 |
| 55 | Abdominal distention (HP:0003270) | 2.19074824 |
| 56 | Distal upper limb amyotrophy (HP:0007149) | 2.18971327 |
| 57 | Upper limb amyotrophy (HP:0009129) | 2.18971327 |
| 58 | Tongue fasciculations (HP:0001308) | 2.16929612 |
| 59 | Amyloidosis (HP:0011034) | 2.16431892 |
| 60 | Deviation of the thumb (HP:0009603) | 2.15396252 |
| 61 | Hepatocellular necrosis (HP:0001404) | 2.14061890 |
| 62 | Hypokinesia (HP:0002375) | 2.12294146 |
| 63 | Hepatic necrosis (HP:0002605) | 2.10537685 |
| 64 | Proximal placement of thumb (HP:0009623) | 2.08633494 |
| 65 | Abnormality of proline metabolism (HP:0010907) | 2.08031666 |
| 66 | Hydroxyprolinuria (HP:0003080) | 2.08031666 |
| 67 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.06811246 |
| 68 | Abnormal protein glycosylation (HP:0012346) | 2.06811246 |
| 69 | Abnormal glycosylation (HP:0012345) | 2.06811246 |
| 70 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.06811246 |
| 71 | Fasciculations (HP:0002380) | 2.06642990 |
| 72 | Ureteral duplication (HP:0000073) | 2.06435632 |
| 73 | Ventricular tachycardia (HP:0004756) | 2.04944711 |
| 74 | Natal tooth (HP:0000695) | 2.02784132 |
| 75 | Amelogenesis imperfecta (HP:0000705) | 2.02004593 |
| 76 | Woolly hair (HP:0002224) | 2.00801730 |
| 77 | Hyperacusis (HP:0010780) | 2.00593496 |
| 78 | Palmar hyperkeratosis (HP:0010765) | 2.00356329 |
| 79 | Hand muscle atrophy (HP:0009130) | 2.00216851 |
| 80 | Lip pit (HP:0100267) | 1.94915047 |
| 81 | Amniotic constriction ring (HP:0009775) | 1.93802744 |
| 82 | Abnormality of placental membranes (HP:0011409) | 1.93802744 |
| 83 | Increased connective tissue (HP:0009025) | 1.92881987 |
| 84 | Focal segmental glomerulosclerosis (HP:0000097) | 1.91021672 |
| 85 | Glomerulosclerosis (HP:0000096) | 1.90475092 |
| 86 | Hypoplasia of dental enamel (HP:0006297) | 1.88650927 |
| 87 | Progressive hearing impairment (HP:0001730) | 1.87112781 |
| 88 | Advanced eruption of teeth (HP:0006288) | 1.87104535 |
| 89 | Achilles tendon contracture (HP:0001771) | 1.87025053 |
| 90 | Abnormality of nail color (HP:0100643) | 1.83836787 |
| 91 | Gout (HP:0001997) | 1.82186450 |
| 92 | Testicular atrophy (HP:0000029) | 1.81505259 |
| 93 | Pterygium (HP:0001059) | 1.79655863 |
| 94 | Secondary amenorrhea (HP:0000869) | 1.79235929 |
| 95 | Down-sloping shoulders (HP:0200021) | 1.78095095 |
| 96 | Abnormal blistering of the skin (HP:0008066) | 1.77515915 |
| 97 | Abnormality of permanent molar morphology (HP:0011071) | 1.75772683 |
| 98 | Abnormality of the dental root (HP:0006486) | 1.75772683 |
| 99 | Taurodontia (HP:0000679) | 1.75772683 |
| 100 | Insulin resistance (HP:0000855) | 1.75225587 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA2 | 7.54578152 |
| 2 | TESK1 | 4.03177955 |
| 3 | MST1R | 3.97937794 |
| 4 | NME2 | 3.69859962 |
| 5 | VRK2 | 3.48962542 |
| 6 | TESK2 | 3.16872527 |
| 7 | LMTK2 | 2.85952854 |
| 8 | MST4 | 2.82858200 |
| 9 | LIMK1 | 2.80038317 |
| 10 | MAP3K12 | 2.70680945 |
| 11 | MAPKAPK3 | 2.27534393 |
| 12 | PAK4 | 2.16142867 |
| 13 | RPS6KB2 | 1.87883087 |
| 14 | ERN1 | 1.86992515 |
| 15 | SIK1 | 1.86381949 |
| 16 | MET | 1.81200685 |
| 17 | SMG1 | 1.64423547 |
| 18 | TRIB3 | 1.62636745 |
| 19 | SCYL2 | 1.60759832 |
| 20 | ARAF | 1.51209383 |
| 21 | IRAK3 | 1.46302624 |
| 22 | BUB1 | 1.42364612 |
| 23 | DAPK1 | 1.39868539 |
| 24 | PIM2 | 1.33131577 |
| 25 | BCKDK | 1.31781141 |
| 26 | PTK2 | 1.29048194 |
| 27 | MAP3K3 | 1.28668645 |
| 28 | PBK | 1.22588663 |
| 29 | ERBB4 | 1.21729338 |
| 30 | NEK1 | 1.20425559 |
| 31 | ILK | 1.15812491 |
| 32 | PKN2 | 1.13099444 |
| 33 | FER | 1.07844361 |
| 34 | EIF2AK1 | 1.07066847 |
| 35 | SIK3 | 1.06721019 |
| 36 | MYLK | 0.99413627 |
| 37 | TSSK6 | 0.98185286 |
| 38 | TRIM28 | 0.98003968 |
| 39 | STK10 | 0.97366632 |
| 40 | EPHB1 | 0.96036080 |
| 41 | PRKCI | 0.95744777 |
| 42 | EPHB2 | 0.90023695 |
| 43 | PTK6 | 0.88757790 |
| 44 | ABL2 | 0.79688329 |
| 45 | RIPK1 | 0.75296654 |
| 46 | LRRK2 | 0.75285539 |
| 47 | CAMK2G | 0.73871753 |
| 48 | SRPK1 | 0.70416787 |
| 49 | STK16 | 0.68959764 |
| 50 | NME1 | 0.64615696 |
| 51 | TAOK2 | 0.64071950 |
| 52 | CDK7 | 0.62488396 |
| 53 | MAP3K9 | 0.59399330 |
| 54 | MAP2K7 | 0.57928779 |
| 55 | PRKG2 | 0.55298748 |
| 56 | MAP2K2 | 0.53966298 |
| 57 | DAPK3 | 0.53683777 |
| 58 | TBK1 | 0.53192128 |
| 59 | AURKB | 0.51166827 |
| 60 | MAP3K2 | 0.47903690 |
| 61 | MAP3K8 | 0.46067726 |
| 62 | AURKA | 0.45548368 |
| 63 | MAPKAPK2 | 0.45292726 |
| 64 | PHKG1 | 0.45010222 |
| 65 | PHKG2 | 0.45010222 |
| 66 | TAF1 | 0.42933078 |
| 67 | CAMK2D | 0.42484495 |
| 68 | CSNK1G3 | 0.40810270 |
| 69 | VRK1 | 0.39889909 |
| 70 | PIK3CA | 0.38024401 |
| 71 | CSNK1A1L | 0.37134597 |
| 72 | PAK1 | 0.37071630 |
| 73 | BMX | 0.36339425 |
| 74 | HIPK2 | 0.34366200 |
| 75 | NEK6 | 0.32105634 |
| 76 | RPS6KA4 | 0.31693788 |
| 77 | GRK5 | 0.29936683 |
| 78 | BRSK1 | 0.29820553 |
| 79 | CAMK2B | 0.29217605 |
| 80 | PDK2 | 0.28245983 |
| 81 | AKT2 | 0.27590365 |
| 82 | ROCK2 | 0.27365340 |
| 83 | MAP2K1 | 0.27084845 |
| 84 | CHUK | 0.26468571 |
| 85 | PLK1 | 0.25851076 |
| 86 | STK38 | 0.24912364 |
| 87 | MUSK | 0.24140077 |
| 88 | CDK12 | 0.23956502 |
| 89 | ERBB2 | 0.23005566 |
| 90 | MAP3K11 | 0.22303627 |
| 91 | BRAF | 0.22081462 |
| 92 | CDK8 | 0.21525489 |
| 93 | EIF2AK2 | 0.21282854 |
| 94 | TAOK1 | 0.19620723 |
| 95 | KDR | 0.17604896 |
| 96 | MTOR | 0.17594986 |
| 97 | PTK2B | 0.16977767 |
| 98 | ICK | 0.16703513 |
| 99 | ROCK1 | 0.16362072 |
| 100 | CSNK1G1 | 0.15945648 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.45892924 |
| 2 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 3.07615473 |
| 3 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.69049003 |
| 4 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.67629217 |
| 5 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.59083282 |
| 6 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 2.57865495 |
| 7 | Galactose metabolism_Homo sapiens_hsa00052 | 2.56909902 |
| 8 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.52625558 |
| 9 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.34564597 |
| 10 | Glutathione metabolism_Homo sapiens_hsa00480 | 2.34548148 |
| 11 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 2.06409959 |
| 12 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.95528134 |
| 13 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.83580332 |
| 14 | Sulfur relay system_Homo sapiens_hsa04122 | 1.79002504 |
| 15 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.78485930 |
| 16 | Carbon metabolism_Homo sapiens_hsa01200 | 1.72171076 |
| 17 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.69974460 |
| 18 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.62244159 |
| 19 | DNA replication_Homo sapiens_hsa03030 | 1.60222976 |
| 20 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.57476006 |
| 21 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.54280662 |
| 22 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.50883225 |
| 23 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.48362658 |
| 24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.47574226 |
| 25 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.46723647 |
| 26 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.35456408 |
| 27 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.32848808 |
| 28 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.31572675 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.31398473 |
| 30 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.28148334 |
| 31 | Mismatch repair_Homo sapiens_hsa03430 | 1.28094102 |
| 32 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.26713657 |
| 33 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.26624210 |
| 34 | Base excision repair_Homo sapiens_hsa03410 | 1.25049214 |
| 35 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.25004541 |
| 36 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.24025361 |
| 37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.22822845 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.22611008 |
| 39 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.18162167 |
| 40 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.16929423 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.13709866 |
| 42 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.06674361 |
| 43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.06499572 |
| 44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.03422412 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.02276363 |
| 46 | Tight junction_Homo sapiens_hsa04530 | 1.00869495 |
| 47 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.97455108 |
| 48 | Thyroid cancer_Homo sapiens_hsa05216 | 0.96821255 |
| 49 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.95943621 |
| 50 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.94302368 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.91711941 |
| 52 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.90739233 |
| 53 | Huntingtons disease_Homo sapiens_hsa05016 | 0.88811914 |
| 54 | Histidine metabolism_Homo sapiens_hsa00340 | 0.86739651 |
| 55 | RNA polymerase_Homo sapiens_hsa03020 | 0.86557276 |
| 56 | Bladder cancer_Homo sapiens_hsa05219 | 0.83908984 |
| 57 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.81596942 |
| 58 | Other glycan degradation_Homo sapiens_hsa00511 | 0.81269817 |
| 59 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.80487182 |
| 60 | Alzheimers disease_Homo sapiens_hsa05010 | 0.77325454 |
| 61 | Parkinsons disease_Homo sapiens_hsa05012 | 0.76521161 |
| 62 | Ribosome_Homo sapiens_hsa03010 | 0.74842339 |
| 63 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.72993935 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.71840295 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71617538 |
| 66 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.70102631 |
| 67 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.70050453 |
| 68 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.69660940 |
| 69 | Shigellosis_Homo sapiens_hsa05131 | 0.67640040 |
| 70 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.62993359 |
| 71 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.61991928 |
| 72 | Hepatitis C_Homo sapiens_hsa05160 | 0.58617181 |
| 73 | Endocytosis_Homo sapiens_hsa04144 | 0.56985336 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56857398 |
| 75 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.54862504 |
| 76 | Homologous recombination_Homo sapiens_hsa03440 | 0.51821104 |
| 77 | Mineral absorption_Homo sapiens_hsa04978 | 0.51229966 |
| 78 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.50571680 |
| 79 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.49906724 |
| 80 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.49740017 |
| 81 | Lysosome_Homo sapiens_hsa04142 | 0.48849607 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48770708 |
| 83 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.48106724 |
| 84 | Adherens junction_Homo sapiens_hsa04520 | 0.47442877 |
| 85 | Purine metabolism_Homo sapiens_hsa00230 | 0.46355655 |
| 86 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46323975 |
| 87 | RNA transport_Homo sapiens_hsa03013 | 0.46235320 |
| 88 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.42987178 |
| 89 | Spliceosome_Homo sapiens_hsa03040 | 0.39281574 |
| 90 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.39083111 |
| 91 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.38902585 |
| 92 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.36993275 |
| 93 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.35178239 |
| 94 | Peroxisome_Homo sapiens_hsa04146 | 0.34825299 |
| 95 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.34491387 |
| 96 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.33722146 |
| 97 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.33715137 |
| 98 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.33669367 |
| 99 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.33415516 |
| 100 | Legionellosis_Homo sapiens_hsa05134 | 0.32097511 |

