

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of memory T cell differentiation (GO:0043380) | 9.46293595 |
| 2 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 7.46601365 |
| 3 | regulation of RIG-I signaling pathway (GO:0039535) | 6.97713839 |
| 4 | positive regulation of hormone biosynthetic process (GO:0046886) | 6.53131784 |
| 5 | positive regulation of hormone metabolic process (GO:0032352) | 6.08202100 |
| 6 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 6.07070365 |
| 7 | sleep (GO:0030431) | 5.88591726 |
| 8 | positive regulation of protein sumoylation (GO:0033235) | 5.49654116 |
| 9 | regulation of interleukin-13 production (GO:0032656) | 5.21319500 |
| 10 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 5.01916422 |
| 11 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 4.95708203 |
| 12 | tolerance induction (GO:0002507) | 4.66616464 |
| 13 | positive regulation of T cell cytokine production (GO:0002726) | 4.62722716 |
| 14 | negative regulation of heart rate (GO:0010459) | 4.62094910 |
| 15 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.42874317 |
| 16 | negative regulation of T cell mediated immunity (GO:0002710) | 4.36140325 |
| 17 | regulation of establishment of cell polarity (GO:2000114) | 4.33434976 |
| 18 | negative regulation of interleukin-2 production (GO:0032703) | 4.31097927 |
| 19 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.30346354 |
| 20 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.29071240 |
| 21 | positive regulation of glycolytic process (GO:0045821) | 4.28174105 |
| 22 | adenosine metabolic process (GO:0046085) | 4.26856024 |
| 23 | positive regulation of T-helper 1 type immune response (GO:0002827) | 4.24571711 |
| 24 | regulation of glomerular filtration (GO:0003093) | 4.23744498 |
| 25 | positive regulation of defense response to virus by host (GO:0002230) | 4.21078806 |
| 26 | mRNA transcription (GO:0009299) | 4.17733491 |
| 27 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.17507682 |
| 28 | cellular response to interleukin-15 (GO:0071350) | 4.16873015 |
| 29 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.12297151 |
| 30 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 4.09003532 |
| 31 | T-helper cell differentiation (GO:0042093) | 4.09003532 |
| 32 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.04710622 |
| 33 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.04710622 |
| 34 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.97892621 |
| 35 | regulation of interleukin-5 production (GO:0032674) | 3.89625641 |
| 36 | regulation of protein sumoylation (GO:0033233) | 3.89296372 |
| 37 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.87606570 |
| 38 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 3.81218313 |
| 39 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 3.77751079 |
| 40 | regulation of cell killing (GO:0031341) | 3.77403329 |
| 41 | L-fucose catabolic process (GO:0042355) | 3.70345859 |
| 42 | fucose catabolic process (GO:0019317) | 3.70345859 |
| 43 | L-fucose metabolic process (GO:0042354) | 3.70345859 |
| 44 | positive regulation of cell killing (GO:0031343) | 3.65526404 |
| 45 | natural killer cell activation involved in immune response (GO:0002323) | 3.61635449 |
| 46 | positive regulation of circadian rhythm (GO:0042753) | 3.61503375 |
| 47 | positive regulation of fibroblast migration (GO:0010763) | 3.56253699 |
| 48 | response to testosterone (GO:0033574) | 3.51965411 |
| 49 | T cell differentiation involved in immune response (GO:0002292) | 3.51797722 |
| 50 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.51797722 |
| 51 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.51797722 |
| 52 | regulation of T cell chemotaxis (GO:0010819) | 3.50849828 |
| 53 | positive regulation of T cell chemotaxis (GO:0010820) | 3.50849828 |
| 54 | regulation of T-helper 1 type immune response (GO:0002825) | 3.50771777 |
| 55 | cellular response to nicotine (GO:0071316) | 3.48849669 |
| 56 | regulation of germinal center formation (GO:0002634) | 3.43809855 |
| 57 | mast cell activation involved in immune response (GO:0002279) | 3.42685849 |
| 58 | mast cell degranulation (GO:0043303) | 3.42685849 |
| 59 | positive regulation of prostaglandin secretion (GO:0032308) | 3.41986110 |
| 60 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.39489733 |
| 61 | lymph node development (GO:0048535) | 3.37729658 |
| 62 | response to misfolded protein (GO:0051788) | 3.34290047 |
| 63 | tumor necrosis factor-mediated signaling pathway (GO:0033209) | 3.29519992 |
| 64 | mRNA cleavage (GO:0006379) | 3.29100596 |
| 65 | cellular response to interleukin-4 (GO:0071353) | 3.25907205 |
| 66 | protein deneddylation (GO:0000338) | 3.25675841 |
| 67 | response to interleukin-15 (GO:0070672) | 3.22626377 |
| 68 | negative regulation of multicellular organism growth (GO:0040015) | 3.20789153 |
| 69 | leukocyte degranulation (GO:0043299) | 3.20400023 |
| 70 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.16347587 |
| 71 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.13744554 |
| 72 | negative regulation of cell killing (GO:0031342) | 3.13744554 |
| 73 | macroautophagy (GO:0016236) | 3.11961957 |
| 74 | NIK/NF-kappaB signaling (GO:0038061) | 3.10175348 |
| 75 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.10118185 |
| 76 | positive regulation of cell fate commitment (GO:0010455) | 3.07821564 |
| 77 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.07655282 |
| 78 | nucleoside diphosphate catabolic process (GO:0009134) | 3.05213663 |
| 79 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.03356362 |
| 80 | trivalent inorganic anion homeostasis (GO:0072506) | 3.03070518 |
| 81 | phosphate ion homeostasis (GO:0055062) | 3.03070518 |
| 82 | N-glycan processing (GO:0006491) | 3.00645406 |
| 83 | positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) | 3.00563955 |
| 84 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.00082732 |
| 85 | regulation of T cell cytokine production (GO:0002724) | 2.99800015 |
| 86 | positive regulation of heat generation (GO:0031652) | 2.98235864 |
| 87 | positive regulation of osteoclast differentiation (GO:0045672) | 2.96548956 |
| 88 | regulation of defense response to virus by host (GO:0050691) | 2.94124466 |
| 89 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.92485343 |
| 90 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.92422697 |
| 91 | positive regulation of erythrocyte differentiation (GO:0045648) | 2.90902595 |
| 92 | regulation of activation of Janus kinase activity (GO:0010533) | 2.90352879 |
| 93 | protein polyglutamylation (GO:0018095) | 2.86549988 |
| 94 | positive regulation vascular endothelial growth factor production (GO:0010575) | 2.86187293 |
| 95 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.85746509 |
| 96 | termination of RNA polymerase I transcription (GO:0006363) | 2.85073779 |
| 97 | hepatocyte apoptotic process (GO:0097284) | 2.84907262 |
| 98 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.82650264 |
| 99 | positive regulation of T cell mediated immunity (GO:0002711) | 2.82331166 |
| 100 | renal system process involved in regulation of blood volume (GO:0001977) | 2.81601157 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 6.05257023 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.95908484 |
| 3 | IRF1_19129219_ChIP-ChIP_H3396_Human | 3.38857850 |
| 4 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.36942684 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.33743028 |
| 6 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.10834641 |
| 7 | GATA1_22025678_ChIP-Seq_K562_Human | 3.05500355 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.01459727 |
| 9 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.35709813 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.28686925 |
| 11 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 2.21882301 |
| 12 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.07733774 |
| 13 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.04187077 |
| 14 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.02161947 |
| 15 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.99388854 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.95400440 |
| 17 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.90428600 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 1.88492937 |
| 19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.84635018 |
| 20 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.82992274 |
| 21 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.75696774 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.74537305 |
| 23 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.70510232 |
| 24 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.69952560 |
| 25 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.67638607 |
| 26 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.67055570 |
| 27 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.66000248 |
| 28 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.65042089 |
| 29 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59932391 |
| 30 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.56128299 |
| 31 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.55149423 |
| 32 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.46772845 |
| 33 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.46673353 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.41297918 |
| 35 | GATA3_26560356_Chip-Seq_TH2_Human | 1.40660799 |
| 36 | ERA_21632823_ChIP-Seq_H3396_Human | 1.39124255 |
| 37 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.37800846 |
| 38 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.37257646 |
| 39 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.35793420 |
| 40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.31601024 |
| 41 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.31233359 |
| 42 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.30719742 |
| 43 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.28932876 |
| 44 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.28166825 |
| 45 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.27894711 |
| 46 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.26270416 |
| 47 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.25957945 |
| 48 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.23827127 |
| 49 | P68_20966046_ChIP-Seq_HELA_Human | 1.17716461 |
| 50 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.16714751 |
| 51 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.15528569 |
| 52 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.15092651 |
| 53 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.14867129 |
| 54 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.12944558 |
| 55 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12835342 |
| 56 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.11900844 |
| 57 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.11375699 |
| 58 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.10639331 |
| 59 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10060152 |
| 60 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.09201482 |
| 61 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.08844962 |
| 62 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.07907040 |
| 63 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.07827357 |
| 64 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.06780702 |
| 65 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.06234522 |
| 66 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.05146382 |
| 67 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.05111319 |
| 68 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.05003038 |
| 69 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.04921559 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.04635801 |
| 71 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.04146699 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03563242 |
| 73 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.01947860 |
| 74 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.01494394 |
| 75 | MAF_26560356_Chip-Seq_TH2_Human | 1.00092501 |
| 76 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.99927329 |
| 77 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98590325 |
| 78 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.97370349 |
| 79 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.96970366 |
| 80 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.96625270 |
| 81 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.96566488 |
| 82 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94454725 |
| 83 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.94225975 |
| 84 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.93474939 |
| 85 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.93411634 |
| 86 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.91942258 |
| 87 | MAF_26560356_Chip-Seq_TH1_Human | 0.91105459 |
| 88 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.89814573 |
| 89 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.89014038 |
| 90 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.88735306 |
| 91 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87867058 |
| 92 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.86967817 |
| 93 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.86893279 |
| 94 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.86567255 |
| 95 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86137294 |
| 96 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.85229482 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.84920317 |
| 98 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.84648507 |
| 99 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.83762106 |
| 100 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.82885223 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005075_abnormal_melanosome_morpholog | 5.95144205 |
| 2 | MP0002877_abnormal_melanocyte_morpholog | 4.56604120 |
| 3 | MP0002796_impaired_skin_barrier | 3.90511278 |
| 4 | MP0004381_abnormal_hair_follicle | 3.30679699 |
| 5 | MP0005671_abnormal_response_to | 3.23642009 |
| 6 | MP0003878_abnormal_ear_physiology | 2.89874338 |
| 7 | MP0005377_hearing/vestibular/ear_phenot | 2.89874338 |
| 8 | MP0003724_increased_susceptibility_to | 2.85487266 |
| 9 | MP0004264_abnormal_extraembryonic_tissu | 2.79970126 |
| 10 | MP0004147_increased_porphyrin_level | 2.32399046 |
| 11 | MP0005501_abnormal_skin_physiology | 2.23784318 |
| 12 | MP0001790_abnormal_immune_system | 2.16280902 |
| 13 | MP0005387_immune_system_phenotype | 2.16280902 |
| 14 | MP0000465_gastrointestinal_hemorrhage | 2.14088135 |
| 15 | MP0000372_irregular_coat_pigmentation | 2.13176726 |
| 16 | MP0001881_abnormal_mammary_gland | 2.00339945 |
| 17 | MP0002736_abnormal_nociception_after | 1.99098815 |
| 18 | MP0000685_abnormal_immune_system | 1.98115474 |
| 19 | MP0003638_abnormal_response/metabolism_ | 1.79211105 |
| 20 | MP0003763_abnormal_thymus_physiology | 1.79082366 |
| 21 | MP0005174_abnormal_tail_pigmentation | 1.77247634 |
| 22 | MP0003195_calcinosis | 1.76401064 |
| 23 | MP0004885_abnormal_endolymph | 1.66933587 |
| 24 | MP0000371_diluted_coat_color | 1.66192349 |
| 25 | MP0001853_heart_inflammation | 1.64121312 |
| 26 | MP0001873_stomach_inflammation | 1.63849609 |
| 27 | MP0000383_abnormal_hair_follicle | 1.60282925 |
| 28 | MP0000627_abnormal_mammary_gland | 1.57268744 |
| 29 | MP0003011_delayed_dark_adaptation | 1.52395143 |
| 30 | MP0005000_abnormal_immune_tolerance | 1.49388633 |
| 31 | MP0003828_pulmonary_edema | 1.45778390 |
| 32 | MP0002102_abnormal_ear_morphology | 1.43735193 |
| 33 | MP0003879_abnormal_hair_cell | 1.39451757 |
| 34 | MP0004043_abnormal_pH_regulation | 1.39109790 |
| 35 | MP0004947_skin_inflammation | 1.38315300 |
| 36 | MP0003303_peritoneal_inflammation | 1.37164939 |
| 37 | MP0008872_abnormal_physiological_respon | 1.36224608 |
| 38 | MP0003252_abnormal_bile_duct | 1.34046155 |
| 39 | MP0009780_abnormal_chondrocyte_physiolo | 1.31002096 |
| 40 | MP0000569_abnormal_digit_pigmentation | 1.29281896 |
| 41 | MP0001800_abnormal_humoral_immune | 1.29027297 |
| 42 | MP0001968_abnormal_touch/_nociception | 1.28420750 |
| 43 | MP0002723_abnormal_immune_serum | 1.26599896 |
| 44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25560816 |
| 45 | MP0001819_abnormal_immune_cell | 1.25455561 |
| 46 | MP0003453_abnormal_keratinocyte_physiol | 1.25417338 |
| 47 | MP0002098_abnormal_vibrissa_morphology | 1.25053340 |
| 48 | MP0001216_abnormal_epidermal_layer | 1.22644997 |
| 49 | MP0002420_abnormal_adaptive_immunity | 1.22248389 |
| 50 | MP0005408_hypopigmentation | 1.20717718 |
| 51 | MP0000427_abnormal_hair_cycle | 1.11810732 |
| 52 | MP0001835_abnormal_antigen_presentation | 1.11641465 |
| 53 | MP0003866_abnormal_defecation | 1.11325045 |
| 54 | MP0010771_integument_phenotype | 1.10307639 |
| 55 | MP0001188_hyperpigmentation | 1.09189417 |
| 56 | MP0002452_abnormal_antigen_presenting | 1.09020452 |
| 57 | MP0002876_abnormal_thyroid_physiology | 1.08722396 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.08044242 |
| 59 | MP0002722_abnormal_immune_system | 1.07334737 |
| 60 | MP0002933_joint_inflammation | 1.03682735 |
| 61 | MP0000367_abnormal_coat/_hair | 1.00800560 |
| 62 | MP0000377_abnormal_hair_follicle | 1.00191735 |
| 63 | MP0000716_abnormal_immune_system | 1.00187009 |
| 64 | MP0003936_abnormal_reproductive_system | 0.99659404 |
| 65 | MP0002405_respiratory_system_inflammati | 0.98751145 |
| 66 | MP0001664_abnormal_digestion | 0.97029482 |
| 67 | MP0002148_abnormal_hypersensitivity_rea | 0.95247497 |
| 68 | MP0001529_abnormal_vocalization | 0.94532552 |
| 69 | MP0000609_abnormal_liver_physiology | 0.93543806 |
| 70 | MP0001485_abnormal_pinna_reflex | 0.91962972 |
| 71 | MP0005410_abnormal_fertilization | 0.90734049 |
| 72 | MP0002938_white_spotting | 0.90302318 |
| 73 | MP0003786_premature_aging | 0.90163241 |
| 74 | MP0000689_abnormal_spleen_morphology | 0.89717198 |
| 75 | MP0002075_abnormal_coat/hair_pigmentati | 0.89610359 |
| 76 | MP0010678_abnormal_skin_adnexa | 0.89173018 |
| 77 | MP0002429_abnormal_blood_cell | 0.88837559 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 0.85842026 |
| 79 | MP0001905_abnormal_dopamine_level | 0.81748418 |
| 80 | MP0000703_abnormal_thymus_morphology | 0.80733573 |
| 81 | MP0002398_abnormal_bone_marrow | 0.79891620 |
| 82 | MP0008874_decreased_physiological_sensi | 0.79049814 |
| 83 | MP0006072_abnormal_retinal_apoptosis | 0.77580857 |
| 84 | MP0002138_abnormal_hepatobiliary_system | 0.77370942 |
| 85 | MP0001845_abnormal_inflammatory_respons | 0.76765587 |
| 86 | MP0003172_abnormal_lysosome_physiology | 0.76181656 |
| 87 | MP0000015_abnormal_ear_pigmentation | 0.74806067 |
| 88 | MP0008789_abnormal_olfactory_epithelium | 0.74675675 |
| 89 | MP0006036_abnormal_mitochondrial_physio | 0.74273488 |
| 90 | MP0000538_abnormal_urinary_bladder | 0.73347858 |
| 91 | MP0001851_eye_inflammation | 0.72952876 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 0.71008182 |
| 93 | MP0004019_abnormal_vitamin_homeostasis | 0.70291943 |
| 94 | MP0001765_abnormal_ion_homeostasis | 0.69056648 |
| 95 | MP0000358_abnormal_cell_content/ | 0.69001174 |
| 96 | MP0008260_abnormal_autophagy | 0.67712170 |
| 97 | MP0005076_abnormal_cell_differentiation | 0.66565664 |
| 98 | MP0000462_abnormal_digestive_system | 0.66331656 |
| 99 | MP0005360_urolithiasis | 0.65848795 |
| 100 | MP0001727_abnormal_embryo_implantation | 0.65177834 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Brittle hair (HP:0002299) | 5.90557572 |
| 2 | Hypotrichosis (HP:0001006) | 5.88169378 |
| 3 | Genetic anticipation (HP:0003743) | 4.68183261 |
| 4 | Abnormality of dental color (HP:0011073) | 4.01083914 |
| 5 | Dysmetric saccades (HP:0000641) | 3.99719398 |
| 6 | Anhidrosis (HP:0000970) | 3.89970058 |
| 7 | Slow saccadic eye movements (HP:0000514) | 3.72378122 |
| 8 | Prostate neoplasm (HP:0100787) | 3.48331888 |
| 9 | Severe combined immunodeficiency (HP:0004430) | 3.41009325 |
| 10 | Slow-growing hair (HP:0002217) | 3.27889760 |
| 11 | Abnormality of hair growth rate (HP:0011363) | 3.27889760 |
| 12 | Abnormality of eosinophils (HP:0001879) | 3.13124730 |
| 13 | Conical tooth (HP:0000698) | 3.12843478 |
| 14 | IgG deficiency (HP:0004315) | 2.98637897 |
| 15 | Progressive cerebellar ataxia (HP:0002073) | 2.96335789 |
| 16 | Hypophosphatemic rickets (HP:0004912) | 2.93640303 |
| 17 | Nail dystrophy (HP:0008404) | 2.86258311 |
| 18 | Facial shape deformation (HP:0011334) | 2.83700188 |
| 19 | Potter facies (HP:0002009) | 2.83700188 |
| 20 | Optic neuritis (HP:0100653) | 2.79792370 |
| 21 | Retrobulbar optic neuritis (HP:0100654) | 2.79792370 |
| 22 | T lymphocytopenia (HP:0005403) | 2.76567952 |
| 23 | Renal cortical cysts (HP:0000803) | 2.74184603 |
| 24 | Progressive muscle weakness (HP:0003323) | 2.62140735 |
| 25 | J-shaped sella turcica (HP:0002680) | 2.61607448 |
| 26 | Abnormality of the frontal sinuses (HP:0002687) | 2.60950455 |
| 27 | 3-Methylglutaconic aciduria (HP:0003535) | 2.60439351 |
| 28 | Pili torti (HP:0003777) | 2.58376510 |
| 29 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.55203083 |
| 30 | Combined immunodeficiency (HP:0005387) | 2.49252739 |
| 31 | Abnormality of T cell number (HP:0011839) | 2.47099049 |
| 32 | Abnormality of T cells (HP:0002843) | 2.45897531 |
| 33 | Bulbar palsy (HP:0001283) | 2.44903270 |
| 34 | Abnormality of the renal cortex (HP:0011035) | 2.44677883 |
| 35 | Rhinitis (HP:0012384) | 2.44259144 |
| 36 | Onycholysis (HP:0001806) | 2.40369351 |
| 37 | Molar tooth sign on MRI (HP:0002419) | 2.40350400 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.40350400 |
| 39 | Gastrointestinal stroma tumor (HP:0100723) | 2.39779057 |
| 40 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.31887692 |
| 41 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.31887692 |
| 42 | Abnormality of glycolipid metabolism (HP:0010969) | 2.31887692 |
| 43 | B lymphocytopenia (HP:0010976) | 2.31763122 |
| 44 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.30911532 |
| 45 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.30911532 |
| 46 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.30911532 |
| 47 | Chromsome breakage (HP:0040012) | 2.28541306 |
| 48 | Acute encephalopathy (HP:0006846) | 2.28170406 |
| 49 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.27106199 |
| 50 | Recurrent bronchitis (HP:0002837) | 2.26288034 |
| 51 | Gaze-evoked nystagmus (HP:0000640) | 2.22923224 |
| 52 | Increased density of long bones (HP:0006392) | 2.19181597 |
| 53 | Impaired proprioception (HP:0010831) | 2.19064055 |
| 54 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.16882127 |
| 55 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.16882127 |
| 56 | Abnormal protein glycosylation (HP:0012346) | 2.16882127 |
| 57 | Abnormal glycosylation (HP:0012345) | 2.16882127 |
| 58 | Tubular atrophy (HP:0000092) | 2.16617039 |
| 59 | Hyperammonemia (HP:0001987) | 2.12906012 |
| 60 | Abolished electroretinogram (ERG) (HP:0000550) | 2.12029798 |
| 61 | Chorioretinal atrophy (HP:0000533) | 2.09593395 |
| 62 | Abnormality of T cell physiology (HP:0011840) | 2.08997225 |
| 63 | Germ cell neoplasia (HP:0100728) | 2.07551666 |
| 64 | Abnormality of oral frenula (HP:0000190) | 2.07312723 |
| 65 | Orchitis (HP:0100796) | 2.07100073 |
| 66 | Clitoromegaly (HP:0000057) | 2.06839879 |
| 67 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.06737958 |
| 68 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.06737958 |
| 69 | Limb ataxia (HP:0002070) | 2.06644254 |
| 70 | Abnormality of B cell number (HP:0010975) | 2.06348493 |
| 71 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.03531590 |
| 72 | Dysostosis multiplex (HP:0000943) | 2.02183650 |
| 73 | Duplicated collecting system (HP:0000081) | 1.99394893 |
| 74 | Poor head control (HP:0002421) | 1.99001658 |
| 75 | Absent/shortened dynein arms (HP:0200106) | 1.98975648 |
| 76 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.98975648 |
| 77 | Horseshoe kidney (HP:0000085) | 1.98879428 |
| 78 | Bronchitis (HP:0012387) | 1.98834228 |
| 79 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.98287353 |
| 80 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.97526106 |
| 81 | Abnormal hair laboratory examination (HP:0003328) | 1.95708731 |
| 82 | Arterial thrombosis (HP:0004420) | 1.95124850 |
| 83 | Abnormal ciliary motility (HP:0012262) | 1.93022240 |
| 84 | Abnormality of the prostate (HP:0008775) | 1.93009843 |
| 85 | Vertigo (HP:0002321) | 1.91852408 |
| 86 | Abnormality of the renal collecting system (HP:0004742) | 1.91658296 |
| 87 | Nephronophthisis (HP:0000090) | 1.89424128 |
| 88 | Micronodular cirrhosis (HP:0001413) | 1.87467439 |
| 89 | Hypergonadotropic hypogonadism (HP:0000815) | 1.87272907 |
| 90 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.84864017 |
| 91 | Mucopolysacchariduria (HP:0008155) | 1.84864017 |
| 92 | Hypoplasia of the uterus (HP:0000013) | 1.84496736 |
| 93 | Anorexia (HP:0002039) | 1.83200650 |
| 94 | Abnormality of the pons (HP:0007361) | 1.83080764 |
| 95 | Amelogenesis imperfecta (HP:0000705) | 1.82750516 |
| 96 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.81659904 |
| 97 | Thyroiditis (HP:0100646) | 1.81601415 |
| 98 | Hypophosphatemia (HP:0002148) | 1.80003672 |
| 99 | Gonadal dysgenesis (HP:0000133) | 1.79445630 |
| 100 | Abnormality of the umbilical cord (HP:0010881) | 1.78275493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 7.36089310 |
| 2 | MUSK | 5.12656216 |
| 3 | MATK | 4.03842846 |
| 4 | MAPKAPK3 | 3.68243859 |
| 5 | FES | 3.15011072 |
| 6 | TXK | 2.99301892 |
| 7 | GRK6 | 2.94834832 |
| 8 | MAP3K11 | 2.45797483 |
| 9 | TAOK1 | 2.33096109 |
| 10 | NTRK1 | 2.19372396 |
| 11 | MST4 | 2.12394385 |
| 12 | TAOK2 | 1.96066581 |
| 13 | MAP2K2 | 1.93215396 |
| 14 | MAP3K14 | 1.90268573 |
| 15 | VRK2 | 1.78353477 |
| 16 | NEK6 | 1.77632359 |
| 17 | PIK3CA | 1.65761585 |
| 18 | MARK3 | 1.63857232 |
| 19 | MAP3K3 | 1.51163579 |
| 20 | KIT | 1.49478928 |
| 21 | IRAK3 | 1.44168886 |
| 22 | PINK1 | 1.43165072 |
| 23 | FER | 1.38929574 |
| 24 | CSK | 1.29913234 |
| 25 | RPS6KB2 | 1.29497177 |
| 26 | TLK1 | 1.29038513 |
| 27 | IKBKB | 1.26661294 |
| 28 | SIK3 | 1.23481883 |
| 29 | TIE1 | 1.20779248 |
| 30 | TBK1 | 1.15687174 |
| 31 | BMPR2 | 1.15159600 |
| 32 | MAP3K12 | 1.13240351 |
| 33 | IKBKE | 1.11659048 |
| 34 | PHKG2 | 1.08031016 |
| 35 | PHKG1 | 1.08031016 |
| 36 | NUAK1 | 1.05320276 |
| 37 | EIF2AK2 | 1.04318397 |
| 38 | GRK1 | 1.03512272 |
| 39 | STK10 | 1.03228719 |
| 40 | TESK2 | 1.01197491 |
| 41 | ALK | 1.00890616 |
| 42 | ZAK | 0.99172885 |
| 43 | NLK | 0.97963024 |
| 44 | OXSR1 | 0.89755192 |
| 45 | EIF2AK1 | 0.88917305 |
| 46 | MAP4K1 | 0.88775384 |
| 47 | KDR | 0.77040845 |
| 48 | EPHA2 | 0.76214760 |
| 49 | NEK1 | 0.74468138 |
| 50 | MAP4K2 | 0.70923982 |
| 51 | SIK1 | 0.68864688 |
| 52 | PRKD2 | 0.68574455 |
| 53 | CSNK1G3 | 0.68197984 |
| 54 | JAK1 | 0.66924882 |
| 55 | WNK4 | 0.65879227 |
| 56 | LMTK2 | 0.64374229 |
| 57 | CHUK | 0.62034899 |
| 58 | DAPK1 | 0.60685966 |
| 59 | MAPKAPK2 | 0.59866377 |
| 60 | LCK | 0.56225248 |
| 61 | CHEK2 | 0.56074659 |
| 62 | CSNK1A1L | 0.56071308 |
| 63 | SMG1 | 0.50942045 |
| 64 | ADRBK2 | 0.48848075 |
| 65 | ILK | 0.46535002 |
| 66 | MAP2K3 | 0.46091273 |
| 67 | MAP3K1 | 0.43064413 |
| 68 | FRK | 0.42556846 |
| 69 | CDK3 | 0.41907325 |
| 70 | SRPK1 | 0.40782193 |
| 71 | MAP3K5 | 0.40300573 |
| 72 | PRKCQ | 0.38956537 |
| 73 | TYRO3 | 0.38884675 |
| 74 | INSR | 0.38337238 |
| 75 | PRKCI | 0.37127211 |
| 76 | CDK7 | 0.36589125 |
| 77 | CDK19 | 0.35153109 |
| 78 | JAK3 | 0.32574817 |
| 79 | CSNK1G2 | 0.32027374 |
| 80 | ERBB3 | 0.30326505 |
| 81 | MAP3K7 | 0.29624531 |
| 82 | CDK4 | 0.29391220 |
| 83 | ARAF | 0.27260047 |
| 84 | ERBB2 | 0.27200522 |
| 85 | STK39 | 0.26596257 |
| 86 | IGF1R | 0.26369946 |
| 87 | CSNK1G1 | 0.26073924 |
| 88 | TESK1 | 0.25298892 |
| 89 | FGR | 0.24729677 |
| 90 | MAP2K1 | 0.24354917 |
| 91 | LYN | 0.23475444 |
| 92 | PIM1 | 0.22599327 |
| 93 | VRK1 | 0.21220553 |
| 94 | PDK1 | 0.20871021 |
| 95 | FYN | 0.20819258 |
| 96 | CSNK1D | 0.18179521 |
| 97 | ADRBK1 | 0.17580787 |
| 98 | RPS6KA1 | 0.16821283 |
| 99 | MYLK | 0.16330091 |
| 100 | TTK | 0.16163446 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 5.65389139 |
| 2 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 3.09650508 |
| 3 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.87832904 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.74785706 |
| 5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.59965684 |
| 6 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.50209305 |
| 7 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.48913622 |
| 8 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.45740024 |
| 9 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.26794638 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.15857759 |
| 11 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.12813026 |
| 12 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.95200398 |
| 13 | Thyroid cancer_Homo sapiens_hsa05216 | 1.89204891 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.87799905 |
| 15 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.87352083 |
| 16 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.83576871 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.79853361 |
| 18 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.77669980 |
| 19 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.77018865 |
| 20 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.73411150 |
| 21 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.68340628 |
| 22 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.64751667 |
| 23 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.60358697 |
| 24 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.55469494 |
| 25 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.51383791 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.49005630 |
| 27 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.48900669 |
| 28 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.47534029 |
| 29 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.45924255 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.42205857 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.37336189 |
| 32 | Base excision repair_Homo sapiens_hsa03410 | 1.29140438 |
| 33 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.26027739 |
| 34 | Malaria_Homo sapiens_hsa05144 | 1.21307442 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.17731125 |
| 36 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.16544130 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.12456201 |
| 38 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.08810383 |
| 39 | Apoptosis_Homo sapiens_hsa04210 | 1.07709627 |
| 40 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.05351852 |
| 41 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.04342872 |
| 42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.02689978 |
| 43 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.01714390 |
| 44 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.99717840 |
| 45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.98432675 |
| 46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.97145936 |
| 47 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.96222650 |
| 48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.96140577 |
| 49 | Lysosome_Homo sapiens_hsa04142 | 0.96075174 |
| 50 | Homologous recombination_Homo sapiens_hsa03440 | 0.93603045 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.91197327 |
| 52 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.89235787 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.88455378 |
| 54 | Phototransduction_Homo sapiens_hsa04744 | 0.87252825 |
| 55 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.82911567 |
| 56 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.82666758 |
| 57 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.79755966 |
| 58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.79208139 |
| 59 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.77738238 |
| 60 | Proteasome_Homo sapiens_hsa03050 | 0.76478761 |
| 61 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.75475934 |
| 62 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.74621946 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63605384 |
| 64 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.60903448 |
| 65 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.59835118 |
| 66 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.59040576 |
| 67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.59034455 |
| 68 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.56331887 |
| 69 | Ribosome_Homo sapiens_hsa03010 | 0.56037150 |
| 70 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.55890689 |
| 71 | Mineral absorption_Homo sapiens_hsa04978 | 0.54987802 |
| 72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.54473761 |
| 73 | RNA degradation_Homo sapiens_hsa03018 | 0.52655165 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.49208224 |
| 75 | Endocytosis_Homo sapiens_hsa04144 | 0.48241362 |
| 76 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47928654 |
| 77 | Spliceosome_Homo sapiens_hsa03040 | 0.45691443 |
| 78 | Peroxisome_Homo sapiens_hsa04146 | 0.45446453 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44929215 |
| 80 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.43934201 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.41296745 |
| 82 | Other glycan degradation_Homo sapiens_hsa00511 | 0.38446579 |
| 83 | Measles_Homo sapiens_hsa05162 | 0.37178721 |
| 84 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.35136165 |
| 85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.33560861 |
| 86 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.32155263 |
| 87 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.31904955 |
| 88 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.30507875 |
| 89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.29949184 |
| 90 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.29189012 |
| 91 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.26026013 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.25436108 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.24375852 |
| 94 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.23092587 |
| 95 | Legionellosis_Homo sapiens_hsa05134 | 0.22519278 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.19118973 |
| 97 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.19094426 |
| 98 | Circadian rhythm_Homo sapiens_hsa04710 | 0.19018455 |
| 99 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.18244451 |
| 100 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.16692268 |

