

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein maturation by protein folding (GO:0022417) | 4.92405992 |
| 2 | regulation of mitochondrial translation (GO:0070129) | 4.88856794 |
| 3 | proteasome assembly (GO:0043248) | 4.80865211 |
| 4 | COPI coating of Golgi vesicle (GO:0048205) | 4.42916182 |
| 5 | Golgi transport vesicle coating (GO:0048200) | 4.42916182 |
| 6 | protein retention in ER lumen (GO:0006621) | 4.38857057 |
| 7 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.37149295 |
| 8 | cell adhesion mediated by integrin (GO:0033627) | 3.72025252 |
| 9 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.69010224 |
| 10 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.60718756 |
| 11 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.58982738 |
| 12 | GDP-mannose metabolic process (GO:0019673) | 3.58824901 |
| 13 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.53145956 |
| 14 | L-phenylalanine metabolic process (GO:0006558) | 3.53145956 |
| 15 | GTP biosynthetic process (GO:0006183) | 3.44662942 |
| 16 | UTP biosynthetic process (GO:0006228) | 3.42911581 |
| 17 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.37385521 |
| 18 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.36900386 |
| 19 | negative regulation of ligase activity (GO:0051352) | 3.36900386 |
| 20 | regulation of metalloenzyme activity (GO:0048552) | 3.36507679 |
| 21 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.32739413 |
| 22 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 3.26732171 |
| 23 | ribosome assembly (GO:0042255) | 3.26564289 |
| 24 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.22051345 |
| 25 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.19016449 |
| 26 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.19016449 |
| 27 | mitotic nuclear envelope reassembly (GO:0007084) | 3.18303454 |
| 28 | nuclear envelope reassembly (GO:0031468) | 3.18303454 |
| 29 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.14828228 |
| 30 | artery smooth muscle contraction (GO:0014824) | 3.14081529 |
| 31 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.13055888 |
| 32 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.13055888 |
| 33 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.11307465 |
| 34 | desmosome organization (GO:0002934) | 3.10347204 |
| 35 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.08670222 |
| 36 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.08670222 |
| 37 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.08670222 |
| 38 | ribosome biogenesis (GO:0042254) | 3.07942946 |
| 39 | tonic smooth muscle contraction (GO:0014820) | 3.07503496 |
| 40 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.06109601 |
| 41 | UTP metabolic process (GO:0046051) | 3.03367735 |
| 42 | xenobiotic catabolic process (GO:0042178) | 3.02825203 |
| 43 | prostaglandin biosynthetic process (GO:0001516) | 3.02701960 |
| 44 | prostanoid biosynthetic process (GO:0046457) | 3.02701960 |
| 45 | basement membrane organization (GO:0071711) | 3.01794587 |
| 46 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.00946936 |
| 47 | glutamine family amino acid biosynthetic process (GO:0009084) | 2.99475600 |
| 48 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.99393184 |
| 49 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.95369186 |
| 50 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.94209083 |
| 51 | positive regulation of ligase activity (GO:0051351) | 2.94107344 |
| 52 | CTP metabolic process (GO:0046036) | 2.93808830 |
| 53 | CTP biosynthetic process (GO:0006241) | 2.93808830 |
| 54 | ER overload response (GO:0006983) | 2.92261095 |
| 55 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.91907151 |
| 56 | negative regulation of B cell apoptotic process (GO:0002903) | 2.89570168 |
| 57 | ribosomal large subunit biogenesis (GO:0042273) | 2.89457695 |
| 58 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.86058030 |
| 59 | cobalamin metabolic process (GO:0009235) | 2.85887758 |
| 60 | protein heterotetramerization (GO:0051290) | 2.85205418 |
| 61 | formation of translation preinitiation complex (GO:0001731) | 2.85038290 |
| 62 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.77972758 |
| 63 | mitotic metaphase plate congression (GO:0007080) | 2.77340759 |
| 64 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.76156602 |
| 65 | endothelial cell morphogenesis (GO:0001886) | 2.74611947 |
| 66 | atrioventricular valve morphogenesis (GO:0003181) | 2.71539711 |
| 67 | galactose catabolic process (GO:0019388) | 2.70770531 |
| 68 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.70455647 |
| 69 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.69567550 |
| 70 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.68733847 |
| 71 | regulation of cardioblast differentiation (GO:0051890) | 2.68585267 |
| 72 | actin filament depolymerization (GO:0030042) | 2.68162477 |
| 73 | establishment of integrated proviral latency (GO:0075713) | 2.68038180 |
| 74 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.67198847 |
| 75 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.66719675 |
| 76 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.66151771 |
| 77 | regulation of cellular amine metabolic process (GO:0033238) | 2.65429007 |
| 78 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.65323540 |
| 79 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.65137853 |
| 80 | mitotic sister chromatid segregation (GO:0000070) | 2.64650183 |
| 81 | positive regulation of osteoblast proliferation (GO:0033690) | 2.63847158 |
| 82 | skin morphogenesis (GO:0043589) | 2.61136728 |
| 83 | doxorubicin metabolic process (GO:0044598) | 2.61127098 |
| 84 | daunorubicin metabolic process (GO:0044597) | 2.61127098 |
| 85 | polyketide metabolic process (GO:0030638) | 2.61127098 |
| 86 | regulation of gonadotropin secretion (GO:0032276) | 2.60468181 |
| 87 | DNA unwinding involved in DNA replication (GO:0006268) | 2.60460219 |
| 88 | positive regulation of cell cycle arrest (GO:0071158) | 2.60184584 |
| 89 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.57213718 |
| 90 | regulation of ligase activity (GO:0051340) | 2.56844894 |
| 91 | tRNA methylation (GO:0030488) | 2.56213844 |
| 92 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.55984213 |
| 93 | nucleoside transmembrane transport (GO:1901642) | 2.55632741 |
| 94 | pseudouridine synthesis (GO:0001522) | 2.55440371 |
| 95 | response to gravity (GO:0009629) | 2.55076275 |
| 96 | pentose-phosphate shunt (GO:0006098) | 2.54201504 |
| 97 | ncRNA 3-end processing (GO:0043628) | 2.51718409 |
| 98 | positive regulation of pseudopodium assembly (GO:0031274) | 2.50772234 |
| 99 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.50260453 |
| 100 | pentose metabolic process (GO:0019321) | 2.48190101 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.02752613 |
| 2 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.48192794 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.33076704 |
| 4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.21022219 |
| 5 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.11890740 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.83732225 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.80682748 |
| 8 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.72901899 |
| 9 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.64665481 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.64537175 |
| 11 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.61535197 |
| 12 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.50639394 |
| 13 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.41124329 |
| 14 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.37229389 |
| 15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.36367557 |
| 16 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.30385579 |
| 17 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.20026721 |
| 18 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.13792537 |
| 19 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.12049944 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.05458656 |
| 21 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 2.04353525 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.01881124 |
| 23 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 2.01724907 |
| 24 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.01071272 |
| 25 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.99830460 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.99087155 |
| 27 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.91070742 |
| 28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.88878553 |
| 29 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.80514096 |
| 30 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.76565981 |
| 31 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.74198892 |
| 32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.73244944 |
| 33 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.70196515 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.68414412 |
| 35 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.65821186 |
| 36 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.65483800 |
| 37 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.64506647 |
| 38 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.64001719 |
| 39 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.59683326 |
| 40 | ATF3_27146783_Chip-Seq_COLON_Human | 1.59366315 |
| 41 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.55753034 |
| 42 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.54018641 |
| 43 | * PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.51426310 |
| 44 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.50975620 |
| 45 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.50922302 |
| 46 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.50631805 |
| 47 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.50631805 |
| 48 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50482228 |
| 49 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.49190395 |
| 50 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.48681376 |
| 51 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.46522708 |
| 52 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.41990277 |
| 53 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.40478119 |
| 54 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.40099523 |
| 55 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.38922669 |
| 56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.38545756 |
| 57 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.34778853 |
| 58 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.34187103 |
| 59 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.32798398 |
| 60 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.31326324 |
| 61 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.31320365 |
| 62 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.29236908 |
| 63 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.27412360 |
| 64 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.25280991 |
| 65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25135928 |
| 66 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.24694514 |
| 67 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.23988722 |
| 68 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.21075162 |
| 69 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.20958220 |
| 70 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.20874253 |
| 71 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.19026983 |
| 72 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.19025964 |
| 73 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.17393182 |
| 74 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.17060701 |
| 75 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.16694961 |
| 76 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.15990078 |
| 77 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.15885232 |
| 78 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.14341167 |
| 79 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.10706684 |
| 80 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.10531436 |
| 81 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.09999655 |
| 82 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09607886 |
| 83 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.08915484 |
| 84 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.08612144 |
| 85 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.07836350 |
| 86 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04085491 |
| 87 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.04028144 |
| 88 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.03739148 |
| 89 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.03616283 |
| 90 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.03294612 |
| 91 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.02744940 |
| 92 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.01112362 |
| 93 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.00436017 |
| 94 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.00286370 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.00188588 |
| 96 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99795220 |
| 97 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.98902544 |
| 98 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.94799273 |
| 99 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.94658047 |
| 100 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.93875226 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010234_abnormal_vibrissa_follicle | 4.54429044 |
| 2 | MP0003950_abnormal_plasma_membrane | 3.81733831 |
| 3 | MP0008438_abnormal_cutaneous_collagen | 3.51683044 |
| 4 | MP0000537_abnormal_urethra_morphology | 3.10511961 |
| 5 | MP0005360_urolithiasis | 3.08526040 |
| 6 | MP0010352_gastrointestinal_tract_polyps | 3.07819350 |
| 7 | MP0004272_abnormal_basement_membrane | 2.63785191 |
| 8 | MP0003566_abnormal_cell_adhesion | 2.57408374 |
| 9 | MP0001853_heart_inflammation | 2.34387958 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.26274588 |
| 11 | MP0003693_abnormal_embryo_hatching | 2.21221174 |
| 12 | MP0002877_abnormal_melanocyte_morpholog | 2.19935674 |
| 13 | MP0005451_abnormal_body_composition | 2.01664715 |
| 14 | MP0001666_abnormal_nutrient_absorption | 1.81442122 |
| 15 | MP0002796_impaired_skin_barrier | 1.80181166 |
| 16 | MP0000751_myopathy | 1.77969706 |
| 17 | MP0004957_abnormal_blastocyst_morpholog | 1.74549086 |
| 18 | MP0005058_abnormal_lysosome_morphology | 1.72395155 |
| 19 | MP0003806_abnormal_nucleotide_metabolis | 1.67592048 |
| 20 | MP0010030_abnormal_orbit_morphology | 1.66988124 |
| 21 | MP0005623_abnormal_meninges_morphology | 1.64439727 |
| 22 | MP0002060_abnormal_skin_morphology | 1.62229509 |
| 23 | MP0005023_abnormal_wound_healing | 1.61146062 |
| 24 | MP0006054_spinal_hemorrhage | 1.58265858 |
| 25 | MP0010386_abnormal_urinary_bladder | 1.56811665 |
| 26 | MP0000462_abnormal_digestive_system | 1.52014161 |
| 27 | MP0002163_abnormal_gland_morphology | 1.50783118 |
| 28 | MP0005501_abnormal_skin_physiology | 1.50687091 |
| 29 | MP0005670_abnormal_white_adipose | 1.45047109 |
| 30 | MP0003191_abnormal_cellular_cholesterol | 1.42220651 |
| 31 | MP0005365_abnormal_bile_salt | 1.41744575 |
| 32 | MP0003315_abnormal_perineum_morphology | 1.37929142 |
| 33 | MP0001958_emphysema | 1.37673450 |
| 34 | MP0000647_abnormal_sebaceous_gland | 1.36855639 |
| 35 | MP0005257_abnormal_intraocular_pressure | 1.36705897 |
| 36 | MP0000538_abnormal_urinary_bladder | 1.34358178 |
| 37 | MP0001661_extended_life_span | 1.32280295 |
| 38 | MP0009780_abnormal_chondrocyte_physiolo | 1.23226746 |
| 39 | MP0000613_abnormal_salivary_gland | 1.22744088 |
| 40 | MP0004782_abnormal_surfactant_physiolog | 1.22644538 |
| 41 | MP0009697_abnormal_copulation | 1.22021282 |
| 42 | MP0005083_abnormal_biliary_tract | 1.21250071 |
| 43 | MP0003300_gastrointestinal_ulcer | 1.20414237 |
| 44 | MP0004233_abnormal_muscle_weight | 1.18998170 |
| 45 | MP0008260_abnormal_autophagy | 1.17716011 |
| 46 | MP0008932_abnormal_embryonic_tissue | 1.16334203 |
| 47 | MP0003111_abnormal_nucleus_morphology | 1.16021171 |
| 48 | MP0003786_premature_aging | 1.15591572 |
| 49 | MP0001216_abnormal_epidermal_layer | 1.14419199 |
| 50 | MP0001730_embryonic_growth_arrest | 1.13322207 |
| 51 | MP0001849_ear_inflammation | 1.10448953 |
| 52 | MP0002139_abnormal_hepatobiliary_system | 1.10324803 |
| 53 | MP0003705_abnormal_hypodermis_morpholog | 1.09554367 |
| 54 | MP0000749_muscle_degeneration | 1.06201747 |
| 55 | MP0005084_abnormal_gallbladder_morpholo | 1.06043293 |
| 56 | MP0003941_abnormal_skin_development | 1.05189061 |
| 57 | MP0000467_abnormal_esophagus_morphology | 1.04305777 |
| 58 | MP0009840_abnormal_foam_cell | 1.04101934 |
| 59 | MP0003123_paternal_imprinting | 1.03058456 |
| 60 | MP0010771_integument_phenotype | 1.01499579 |
| 61 | MP0005330_cardiomyopathy | 1.00426554 |
| 62 | MP0004185_abnormal_adipocyte_glucose | 0.99720168 |
| 63 | MP0003718_maternal_effect | 0.98165113 |
| 64 | MP0002098_abnormal_vibrissa_morphology | 0.97951531 |
| 65 | MP0004264_abnormal_extraembryonic_tissu | 0.97704566 |
| 66 | MP0000358_abnormal_cell_content/ | 0.94608254 |
| 67 | MP0009384_cardiac_valve_regurgitation | 0.94214682 |
| 68 | MP0000490_abnormal_crypts_of | 0.91656537 |
| 69 | MP0010094_abnormal_chromosome_stability | 0.89681188 |
| 70 | MP0010678_abnormal_skin_adnexa | 0.89444362 |
| 71 | MP0000534_abnormal_ureter_morphology | 0.88755474 |
| 72 | MP0008775_abnormal_heart_ventricle | 0.88647740 |
| 73 | MP0000858_altered_metastatic_potential | 0.87970485 |
| 74 | MP0002089_abnormal_postnatal_growth/wei | 0.86515140 |
| 75 | MP0005319_abnormal_enzyme/_coenzyme | 0.86514784 |
| 76 | MP0003077_abnormal_cell_cycle | 0.83307675 |
| 77 | MP0001542_abnormal_bone_strength | 0.82735958 |
| 78 | MP0003453_abnormal_keratinocyte_physiol | 0.82699921 |
| 79 | MP0001243_abnormal_dermal_layer | 0.80005934 |
| 80 | MP0009053_abnormal_anal_canal | 0.79176255 |
| 81 | MP0000604_amyloidosis | 0.78900514 |
| 82 | MP0005165_increased_susceptibility_to | 0.78802550 |
| 83 | MP0000747_muscle_weakness | 0.78332196 |
| 84 | MP0002080_prenatal_lethality | 0.77331440 |
| 85 | MP0000627_abnormal_mammary_gland | 0.76087364 |
| 86 | MP0001529_abnormal_vocalization | 0.75260947 |
| 87 | MP0002837_dystrophic_cardiac_calcinosis | 0.74487998 |
| 88 | MP0001764_abnormal_homeostasis | 0.73866248 |
| 89 | MP0001672_abnormal_embryogenesis/_devel | 0.73252605 |
| 90 | MP0005380_embryogenesis_phenotype | 0.73252605 |
| 91 | MP0005332_abnormal_amino_acid | 0.72979699 |
| 92 | MP0001756_abnormal_urination | 0.72819392 |
| 93 | MP0001697_abnormal_embryo_size | 0.72478113 |
| 94 | MP0008007_abnormal_cellular_replicative | 0.72208395 |
| 95 | MP0002086_abnormal_extraembryonic_tissu | 0.71151148 |
| 96 | MP0005395_other_phenotype | 0.70953492 |
| 97 | MP0005220_abnormal_exocrine_pancreas | 0.70161388 |
| 98 | MP0000465_gastrointestinal_hemorrhage | 0.69874201 |
| 99 | MP0003646_muscle_fatigue | 0.69041168 |
| 100 | MP0001727_abnormal_embryo_implantation | 0.68475996 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Premature rupture of membranes (HP:0001788) | 4.50235348 |
| 2 | Vascular calcification (HP:0004934) | 4.46821202 |
| 3 | Cardiovascular calcification (HP:0011915) | 4.29991267 |
| 4 | Cutaneous melanoma (HP:0012056) | 4.15628406 |
| 5 | Back pain (HP:0003418) | 3.42960724 |
| 6 | Trismus (HP:0000211) | 3.15207722 |
| 7 | Micronodular cirrhosis (HP:0001413) | 3.07898203 |
| 8 | Vertebral compression fractures (HP:0002953) | 2.98903414 |
| 9 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.92126083 |
| 10 | Short nail (HP:0001799) | 2.84125398 |
| 11 | Limb-girdle muscle atrophy (HP:0003797) | 2.81827539 |
| 12 | Distal upper limb amyotrophy (HP:0007149) | 2.74420600 |
| 13 | Upper limb amyotrophy (HP:0009129) | 2.74420600 |
| 14 | Abnormality of the Achilles tendon (HP:0005109) | 2.71954273 |
| 15 | Distal lower limb muscle weakness (HP:0009053) | 2.68452644 |
| 16 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.65954672 |
| 17 | Ankle contracture (HP:0006466) | 2.63084998 |
| 18 | Glucose intolerance (HP:0000833) | 2.62629774 |
| 19 | Hand muscle atrophy (HP:0009130) | 2.60180251 |
| 20 | Sparse eyelashes (HP:0000653) | 2.57338752 |
| 21 | Abnormality of the umbilical cord (HP:0010881) | 2.54607287 |
| 22 | Rough bone trabeculation (HP:0100670) | 2.53795600 |
| 23 | J-shaped sella turcica (HP:0002680) | 2.47122022 |
| 24 | Generalized amyotrophy (HP:0003700) | 2.46331667 |
| 25 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.42490337 |
| 26 | Microvesicular hepatic steatosis (HP:0001414) | 2.41713531 |
| 27 | Ileus (HP:0002595) | 2.41513448 |
| 28 | Abnormality of placental membranes (HP:0011409) | 2.41193856 |
| 29 | Amniotic constriction ring (HP:0009775) | 2.41193856 |
| 30 | Achilles tendon contracture (HP:0001771) | 2.41018689 |
| 31 | Distal lower limb amyotrophy (HP:0008944) | 2.38908803 |
| 32 | Abnormalities of placenta or umbilical cord (HP:0001194) | 2.38216277 |
| 33 | Ureteral duplication (HP:0000073) | 2.37313539 |
| 34 | Spastic diplegia (HP:0001264) | 2.33515963 |
| 35 | Increased serum pyruvate (HP:0003542) | 2.33259869 |
| 36 | Abnormality of glycolysis (HP:0004366) | 2.31410855 |
| 37 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.29837305 |
| 38 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.29447324 |
| 39 | Protrusio acetabuli (HP:0003179) | 2.22950914 |
| 40 | Follicular hyperkeratosis (HP:0007502) | 2.22627551 |
| 41 | Intrahepatic cholestasis (HP:0001406) | 2.21936474 |
| 42 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.18957685 |
| 43 | Popliteal pterygium (HP:0009756) | 2.16619645 |
| 44 | Hyperammonemia (HP:0001987) | 2.16473587 |
| 45 | Renal tubular acidosis (HP:0001947) | 2.15566684 |
| 46 | Acanthosis nigricans (HP:0000956) | 2.13675477 |
| 47 | Type I transferrin isoform profile (HP:0003642) | 2.13352481 |
| 48 | Osteolytic defects of the hand bones (HP:0009699) | 2.12178995 |
| 49 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.12178995 |
| 50 | Mitral stenosis (HP:0001718) | 2.10904431 |
| 51 | Upper limb muscle weakness (HP:0003484) | 2.10593522 |
| 52 | Elbow flexion contracture (HP:0002987) | 2.10225727 |
| 53 | Hyperglycinemia (HP:0002154) | 2.10088760 |
| 54 | Prolonged neonatal jaundice (HP:0006579) | 2.09732712 |
| 55 | Entropion (HP:0000621) | 2.08938590 |
| 56 | Spastic paraparesis (HP:0002313) | 2.04051143 |
| 57 | Abnormal trabecular bone morphology (HP:0100671) | 2.01714675 |
| 58 | Hypokinesia (HP:0002375) | 2.01206338 |
| 59 | Right ventricular cardiomyopathy (HP:0011663) | 2.00340813 |
| 60 | Lipid accumulation in hepatocytes (HP:0006561) | 1.99021247 |
| 61 | Unilateral renal agenesis (HP:0000122) | 1.95891144 |
| 62 | Hepatocellular carcinoma (HP:0001402) | 1.95403286 |
| 63 | Abdominal distention (HP:0003270) | 1.95111851 |
| 64 | Cervical subluxation (HP:0003308) | 1.87455022 |
| 65 | Subacute progressive viral hepatitis (HP:0006572) | 1.85768088 |
| 66 | Microretrognathia (HP:0000308) | 1.85059323 |
| 67 | Progressive sensorineural hearing impairment (HP:0000408) | 1.84556338 |
| 68 | Aortic dissection (HP:0002647) | 1.83673855 |
| 69 | Testicular atrophy (HP:0000029) | 1.83582054 |
| 70 | Paraparesis (HP:0002385) | 1.83073064 |
| 71 | Decreased subcutaneous fat (HP:0001002) | 1.82909842 |
| 72 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.82419849 |
| 73 | Spinal rigidity (HP:0003306) | 1.82044396 |
| 74 | Aplasia of the musculature (HP:0100854) | 1.81641923 |
| 75 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.81322064 |
| 76 | Renal Fanconi syndrome (HP:0001994) | 1.80587972 |
| 77 | Shoulder girdle muscle weakness (HP:0003547) | 1.79431110 |
| 78 | Opisthotonus (HP:0002179) | 1.79201043 |
| 79 | Hypoalphalipoproteinemia (HP:0003233) | 1.77781560 |
| 80 | Vacuolated lymphocytes (HP:0001922) | 1.76074129 |
| 81 | Atrophic scars (HP:0001075) | 1.75851170 |
| 82 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.75490489 |
| 83 | Fragile skin (HP:0001030) | 1.74872851 |
| 84 | Fat malabsorption (HP:0002630) | 1.73498853 |
| 85 | Slender build (HP:0001533) | 1.73490048 |
| 86 | Sparse lateral eyebrow (HP:0005338) | 1.72951142 |
| 87 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.71388349 |
| 88 | Increased hepatocellular lipid droplets (HP:0006565) | 1.71310518 |
| 89 | Gastrointestinal dysmotility (HP:0002579) | 1.71005202 |
| 90 | Parakeratosis (HP:0001036) | 1.71000883 |
| 91 | Difficulty climbing stairs (HP:0003551) | 1.70451863 |
| 92 | Insulin resistance (HP:0000855) | 1.70212503 |
| 93 | Increased connective tissue (HP:0009025) | 1.70072415 |
| 94 | Deep venous thrombosis (HP:0002625) | 1.70008334 |
| 95 | Hypolipoproteinemia (HP:0010981) | 1.69272623 |
| 96 | Ulnar deviation of the wrist (HP:0003049) | 1.69216754 |
| 97 | Pterygium (HP:0001059) | 1.69185762 |
| 98 | Pelvic girdle muscle weakness (HP:0003749) | 1.69037908 |
| 99 | Abnormal glycosylation (HP:0012345) | 1.67726092 |
| 100 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.67726092 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA2 | 5.55788010 |
| 2 | LMTK2 | 4.02629888 |
| 3 | BUB1 | 3.60611624 |
| 4 | MST1R | 3.20750859 |
| 5 | PBK | 3.13022660 |
| 6 | PAK4 | 3.06252990 |
| 7 | TLK1 | 2.95398191 |
| 8 | TESK1 | 2.84712258 |
| 9 | NME2 | 2.84013629 |
| 10 | ZAK | 2.78254017 |
| 11 | SMG1 | 2.55543481 |
| 12 | VRK2 | 2.53721042 |
| 13 | LIMK1 | 2.26902832 |
| 14 | MYLK | 1.99577010 |
| 15 | IRAK3 | 1.99451414 |
| 16 | MAP3K12 | 1.89579989 |
| 17 | TESK2 | 1.83776480 |
| 18 | PDK2 | 1.77991501 |
| 19 | SCYL2 | 1.68034395 |
| 20 | MET | 1.63992302 |
| 21 | ERN1 | 1.56248749 |
| 22 | RPS6KB2 | 1.52406263 |
| 23 | VRK1 | 1.46811324 |
| 24 | PTK2 | 1.37457586 |
| 25 | MST4 | 1.33100368 |
| 26 | NEK1 | 1.28384319 |
| 27 | AURKA | 1.23586615 |
| 28 | EIF2AK1 | 1.17492307 |
| 29 | BCKDK | 1.14311684 |
| 30 | DAPK3 | 1.13937309 |
| 31 | ABL2 | 1.07807964 |
| 32 | MAP3K8 | 1.03052363 |
| 33 | MAP3K3 | 1.01370135 |
| 34 | AURKB | 1.00607551 |
| 35 | SIK1 | 1.00263214 |
| 36 | CSNK1A1L | 0.99712913 |
| 37 | CDK9 | 0.98687256 |
| 38 | CSNK1G3 | 0.95745274 |
| 39 | TIE1 | 0.93360452 |
| 40 | PRKG2 | 0.93192039 |
| 41 | CDK8 | 0.92123560 |
| 42 | MAPKAPK3 | 0.91697496 |
| 43 | ILK | 0.89050526 |
| 44 | PIM2 | 0.88486033 |
| 45 | ERBB4 | 0.87512968 |
| 46 | STK10 | 0.84885024 |
| 47 | AKT2 | 0.83138843 |
| 48 | DAPK1 | 0.81367220 |
| 49 | FER | 0.79362816 |
| 50 | CAMK2G | 0.79248316 |
| 51 | PTK6 | 0.78773648 |
| 52 | STK4 | 0.78276955 |
| 53 | PLK1 | 0.78266680 |
| 54 | EPHB2 | 0.74637080 |
| 55 | CCNB1 | 0.73205819 |
| 56 | PAK1 | 0.69836105 |
| 57 | ROCK1 | 0.68626435 |
| 58 | STK16 | 0.67215887 |
| 59 | RPS6KA5 | 0.65767087 |
| 60 | CDK7 | 0.62184464 |
| 61 | TTN | 0.58269810 |
| 62 | MAP4K2 | 0.57904536 |
| 63 | ICK | 0.56776410 |
| 64 | TAOK2 | 0.56384538 |
| 65 | NEK2 | 0.55559059 |
| 66 | PRKCI | 0.54725050 |
| 67 | NME1 | 0.53747762 |
| 68 | EIF2AK3 | 0.51602905 |
| 69 | LATS2 | 0.51574144 |
| 70 | MUSK | 0.51367294 |
| 71 | CSNK1G1 | 0.51054034 |
| 72 | WEE1 | 0.49923887 |
| 73 | CAMK2D | 0.49700487 |
| 74 | MAP3K13 | 0.49238675 |
| 75 | TAF1 | 0.47706028 |
| 76 | MELK | 0.46418275 |
| 77 | SRPK1 | 0.46307417 |
| 78 | FGFR4 | 0.45446355 |
| 79 | MOS | 0.44904763 |
| 80 | TTK | 0.43830162 |
| 81 | CSNK1G2 | 0.41960768 |
| 82 | MAP2K2 | 0.41567443 |
| 83 | PLK3 | 0.41228093 |
| 84 | PAK2 | 0.41181780 |
| 85 | MAP2K7 | 0.40507073 |
| 86 | EIF2AK2 | 0.38573956 |
| 87 | BRSK1 | 0.38433071 |
| 88 | CAMK2B | 0.38420752 |
| 89 | CHEK2 | 0.37748594 |
| 90 | GRK1 | 0.36221066 |
| 91 | CHUK | 0.35928424 |
| 92 | LATS1 | 0.33643381 |
| 93 | ARAF | 0.33613246 |
| 94 | CDC7 | 0.31211713 |
| 95 | TSSK6 | 0.30951301 |
| 96 | ROCK2 | 0.30231425 |
| 97 | MAP2K1 | 0.29687735 |
| 98 | PRKD3 | 0.27893946 |
| 99 | STK39 | 0.27740196 |
| 100 | MAP3K11 | 0.25701192 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.63615301 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.02963229 |
| 3 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.90676891 |
| 4 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.73267538 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 2.39035663 |
| 6 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.36977030 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 2.25422468 |
| 8 | Glutathione metabolism_Homo sapiens_hsa00480 | 2.11393582 |
| 9 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.05064841 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.00671862 |
| 11 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.91017992 |
| 12 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.88627804 |
| 13 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.85998043 |
| 14 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.81831678 |
| 15 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.79533907 |
| 16 | Alcoholism_Homo sapiens_hsa05034 | 1.78424115 |
| 17 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.76958207 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.74487153 |
| 19 | Carbon metabolism_Homo sapiens_hsa01200 | 1.73823645 |
| 20 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.60122679 |
| 21 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.57712355 |
| 22 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.57454666 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.53871089 |
| 24 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.50866937 |
| 25 | Galactose metabolism_Homo sapiens_hsa00052 | 1.47883312 |
| 26 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.47564655 |
| 27 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.46444673 |
| 28 | RNA polymerase_Homo sapiens_hsa03020 | 1.41256187 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.37799687 |
| 30 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.36709678 |
| 31 | Mismatch repair_Homo sapiens_hsa03430 | 1.34000562 |
| 32 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.33213553 |
| 33 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.23165131 |
| 34 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.19499497 |
| 35 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.18003561 |
| 36 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.17311998 |
| 37 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.17309738 |
| 38 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.13140298 |
| 39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.12461854 |
| 40 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.08769658 |
| 41 | Spliceosome_Homo sapiens_hsa03040 | 1.08108739 |
| 42 | Other glycan degradation_Homo sapiens_hsa00511 | 1.04874395 |
| 43 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.03410174 |
| 44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.01590854 |
| 45 | RNA transport_Homo sapiens_hsa03013 | 0.95878565 |
| 46 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.93301659 |
| 47 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.90901390 |
| 48 | Ribosome_Homo sapiens_hsa03010 | 0.90462669 |
| 49 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89770947 |
| 50 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.89710944 |
| 51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.89490095 |
| 52 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.86279148 |
| 53 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.84348215 |
| 54 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.84335697 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.81802288 |
| 56 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.81720488 |
| 57 | Tight junction_Homo sapiens_hsa04530 | 0.80844701 |
| 58 | Huntingtons disease_Homo sapiens_hsa05016 | 0.79682616 |
| 59 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.77047364 |
| 60 | Thyroid cancer_Homo sapiens_hsa05216 | 0.76154750 |
| 61 | Parkinsons disease_Homo sapiens_hsa05012 | 0.74769051 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.74185116 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.73536219 |
| 64 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.72236398 |
| 65 | Peroxisome_Homo sapiens_hsa04146 | 0.71736757 |
| 66 | Cell cycle_Homo sapiens_hsa04110 | 0.71511082 |
| 67 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71242020 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.69058505 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.68910435 |
| 70 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.68239424 |
| 71 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.67533180 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66678383 |
| 73 | Bladder cancer_Homo sapiens_hsa05219 | 0.65150937 |
| 74 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.63939851 |
| 75 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.63394258 |
| 76 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.62881218 |
| 77 | Basal transcription factors_Homo sapiens_hsa03022 | 0.60956006 |
| 78 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.57241466 |
| 79 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.56490358 |
| 80 | Homologous recombination_Homo sapiens_hsa03440 | 0.56353998 |
| 81 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.54493019 |
| 82 | Alzheimers disease_Homo sapiens_hsa05010 | 0.54405786 |
| 83 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.52606542 |
| 84 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.52022177 |
| 85 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.50832560 |
| 86 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.50738135 |
| 87 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50582124 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50244691 |
| 89 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.47135138 |
| 90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.45560009 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45285600 |
| 92 | Lysosome_Homo sapiens_hsa04142 | 0.44155211 |
| 93 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.43100538 |
| 94 | Focal adhesion_Homo sapiens_hsa04510 | 0.41898275 |
| 95 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.40299880 |
| 96 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.40275449 |
| 97 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.39293053 |
| 98 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.38993151 |
| 99 | Protein export_Homo sapiens_hsa03060 | 0.38656959 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38369139 |

