

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | leukotriene biosynthetic process (GO:0019370) | 8.89856682 |
| 2 | leukotriene metabolic process (GO:0006691) | 6.97358287 |
| 3 | glutathione metabolic process (GO:0006749) | 6.06251032 |
| 4 | fatty acid derivative biosynthetic process (GO:1901570) | 5.67899699 |
| 5 | icosanoid biosynthetic process (GO:0046456) | 5.67899699 |
| 6 | peptide catabolic process (GO:0043171) | 5.45582174 |
| 7 | GDP-mannose metabolic process (GO:0019673) | 5.32113289 |
| 8 | unsaturated fatty acid biosynthetic process (GO:0006636) | 4.62758217 |
| 9 | NADH metabolic process (GO:0006734) | 4.45322931 |
| 10 | cysteine metabolic process (GO:0006534) | 4.29738329 |
| 11 | glutathione biosynthetic process (GO:0006750) | 4.13975955 |
| 12 | regulation of guanylate cyclase activity (GO:0031282) | 4.08140772 |
| 13 | mitochondrial calcium ion transport (GO:0006851) | 4.08024164 |
| 14 | dopamine transport (GO:0015872) | 4.06390936 |
| 15 | glutathione derivative biosynthetic process (GO:1901687) | 4.02851240 |
| 16 | glutathione derivative metabolic process (GO:1901685) | 4.02851240 |
| 17 | detection of molecule of bacterial origin (GO:0032490) | 4.01616197 |
| 18 | nonribosomal peptide biosynthetic process (GO:0019184) | 3.90632255 |
| 19 | icosanoid metabolic process (GO:0006690) | 3.89556533 |
| 20 | fatty acid derivative metabolic process (GO:1901568) | 3.89556533 |
| 21 | regulation of oxidative phosphorylation (GO:0002082) | 3.85773130 |
| 22 | proteasome assembly (GO:0043248) | 3.83304332 |
| 23 | angiotensin maturation (GO:0002003) | 3.83296492 |
| 24 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.74630684 |
| 25 | xenobiotic catabolic process (GO:0042178) | 3.64204728 |
| 26 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.63299989 |
| 27 | antibacterial humoral response (GO:0019731) | 3.61505855 |
| 28 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.57304533 |
| 29 | viral mRNA export from host cell nucleus (GO:0046784) | 3.55512895 |
| 30 | unsaturated fatty acid metabolic process (GO:0033559) | 3.50974462 |
| 31 | eosinophil chemotaxis (GO:0048245) | 3.49158285 |
| 32 | antimicrobial humoral response (GO:0019730) | 3.49000866 |
| 33 | peptide metabolic process (GO:0006518) | 3.37699806 |
| 34 | fructose metabolic process (GO:0006000) | 3.26569347 |
| 35 | positive regulation of guanylate cyclase activity (GO:0031284) | 3.21493674 |
| 36 | epoxygenase P450 pathway (GO:0019373) | 3.20947573 |
| 37 | carbohydrate phosphorylation (GO:0046835) | 3.20117983 |
| 38 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.18222400 |
| 39 | hepatocyte apoptotic process (GO:0097284) | 3.18133553 |
| 40 | artery smooth muscle contraction (GO:0014824) | 3.17597536 |
| 41 | protein retention in ER lumen (GO:0006621) | 3.14631231 |
| 42 | daunorubicin metabolic process (GO:0044597) | 3.12886448 |
| 43 | polyketide metabolic process (GO:0030638) | 3.12886448 |
| 44 | doxorubicin metabolic process (GO:0044598) | 3.12886448 |
| 45 | L-ascorbic acid metabolic process (GO:0019852) | 3.12801314 |
| 46 | eosinophil migration (GO:0072677) | 3.09712829 |
| 47 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.04705784 |
| 48 | regulation of metalloenzyme activity (GO:0048552) | 3.04252655 |
| 49 | positive regulation of pseudopodium assembly (GO:0031274) | 3.02603927 |
| 50 | regulation of mitochondrial translation (GO:0070129) | 2.99213710 |
| 51 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.95649161 |
| 52 | regulation of vitamin metabolic process (GO:0030656) | 2.94845168 |
| 53 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.94806683 |
| 54 | ATP synthesis coupled proton transport (GO:0015986) | 2.94806683 |
| 55 | cyclooxygenase pathway (GO:0019371) | 2.89782343 |
| 56 | peptide biosynthetic process (GO:0043043) | 2.84859377 |
| 57 | regulation of bile acid biosynthetic process (GO:0070857) | 2.81708167 |
| 58 | digestion (GO:0007586) | 2.81685268 |
| 59 | positive regulation of glycoprotein metabolic process (GO:1903020) | 2.80449955 |
| 60 | protein maturation by protein folding (GO:0022417) | 2.79917178 |
| 61 | negative regulation of epidermal cell differentiation (GO:0045605) | 2.79365951 |
| 62 | intestinal absorption (GO:0050892) | 2.79272435 |
| 63 | positive regulation of cellular amine metabolic process (GO:0033240) | 2.78140047 |
| 64 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 2.77989938 |
| 65 | cobalamin metabolic process (GO:0009235) | 2.77903506 |
| 66 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.77655296 |
| 67 | galactose catabolic process (GO:0019388) | 2.76273483 |
| 68 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.75382641 |
| 69 | synaptic transmission, dopaminergic (GO:0001963) | 2.74332044 |
| 70 | very-low-density lipoprotein particle assembly (GO:0034379) | 2.73550105 |
| 71 | regulation of cellular amine metabolic process (GO:0033238) | 2.70864657 |
| 72 | regulation of cellular extravasation (GO:0002691) | 2.68003738 |
| 73 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.67982367 |
| 74 | regulation of pseudopodium assembly (GO:0031272) | 2.65563536 |
| 75 | GTP biosynthetic process (GO:0006183) | 2.65387581 |
| 76 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.65052084 |
| 77 | glycoside metabolic process (GO:0016137) | 2.62848868 |
| 78 | macrophage activation (GO:0042116) | 2.62618407 |
| 79 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.62096436 |
| 80 | oligosaccharide catabolic process (GO:0009313) | 2.61649119 |
| 81 | prostanoid biosynthetic process (GO:0046457) | 2.61612506 |
| 82 | prostaglandin biosynthetic process (GO:0001516) | 2.61612506 |
| 83 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.61002856 |
| 84 | response to copper ion (GO:0046688) | 2.59302623 |
| 85 | regulation of cellular respiration (GO:0043457) | 2.58527383 |
| 86 | nucleoside diphosphate biosynthetic process (GO:0009133) | 2.58118717 |
| 87 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.57927422 |
| 88 | tonic smooth muscle contraction (GO:0014820) | 2.57655964 |
| 89 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.57369765 |
| 90 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.57266549 |
| 91 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.57266549 |
| 92 | prostanoid metabolic process (GO:0006692) | 2.54557870 |
| 93 | prostaglandin metabolic process (GO:0006693) | 2.54557870 |
| 94 | disruption of cells of other organism (GO:0044364) | 2.53377054 |
| 95 | killing of cells of other organism (GO:0031640) | 2.53377054 |
| 96 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.52615440 |
| 97 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.52615440 |
| 98 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 2.51900647 |
| 99 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 2.51900647 |
| 100 | endocrine process (GO:0050886) | 2.51900647 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.34788048 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.75689586 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.85693481 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.70447024 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.38422454 |
| 6 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.81877057 |
| 7 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 2.52217737 |
| 8 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.42808154 |
| 9 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.38322188 |
| 10 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.34620011 |
| 11 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.33577103 |
| 12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.33015055 |
| 13 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.27399550 |
| 14 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.13949860 |
| 15 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.02965385 |
| 16 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.97824012 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.90629589 |
| 18 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.88003886 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.78739764 |
| 20 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.77442201 |
| 21 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.71302941 |
| 22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.70664187 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.64498226 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.62122524 |
| 25 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.61261001 |
| 26 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.57111752 |
| 27 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.53863374 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.52695147 |
| 29 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.50882687 |
| 30 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.50357916 |
| 31 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.49944754 |
| 32 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49817470 |
| 33 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.48688148 |
| 34 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.47706003 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.42681586 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41383441 |
| 37 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.41099652 |
| 38 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.40957913 |
| 39 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.36035904 |
| 40 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.34389809 |
| 41 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.33944813 |
| 42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.31831607 |
| 43 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.30732427 |
| 44 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.28164368 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26894551 |
| 46 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.23449178 |
| 47 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.23072999 |
| 48 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.21778626 |
| 49 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20743220 |
| 50 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.19539574 |
| 51 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.18096348 |
| 52 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.18090390 |
| 53 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.17852849 |
| 54 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.15207382 |
| 55 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.14582104 |
| 56 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.11515483 |
| 57 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.09527172 |
| 58 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.08892314 |
| 59 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07746794 |
| 60 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.07706517 |
| 61 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.07672489 |
| 62 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.06777148 |
| 63 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.04085219 |
| 64 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.03848607 |
| 65 | P300_27268052_Chip-Seq_Bcells_Human | 1.02775523 |
| 66 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.02436525 |
| 67 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.02365373 |
| 68 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.01787229 |
| 69 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98885603 |
| 70 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98520327 |
| 71 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.97737662 |
| 72 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.97482524 |
| 73 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.97299515 |
| 74 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.95122027 |
| 75 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.94554721 |
| 76 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.94531865 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.93953618 |
| 78 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.93948359 |
| 79 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.93400812 |
| 80 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.93158446 |
| 81 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92970182 |
| 82 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.92965221 |
| 83 | MYB_26560356_Chip-Seq_TH2_Human | 0.92824768 |
| 84 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.92732015 |
| 85 | SA1_27219007_Chip-Seq_Bcells_Human | 0.91804555 |
| 86 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91030514 |
| 87 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.90319025 |
| 88 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.89734140 |
| 89 | ATF3_27146783_Chip-Seq_COLON_Human | 0.89261462 |
| 90 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.89036930 |
| 91 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.88262834 |
| 92 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.88262834 |
| 93 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.88122959 |
| 94 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.87761813 |
| 95 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.87717348 |
| 96 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.86988949 |
| 97 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.86933823 |
| 98 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.86770522 |
| 99 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.86658303 |
| 100 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.86347361 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003183_abnormal_peptide_metabolism | 7.29127145 |
| 2 | MP0005360_urolithiasis | 4.83925368 |
| 3 | MP0002163_abnormal_gland_morphology | 4.72137677 |
| 4 | MP0002139_abnormal_hepatobiliary_system | 4.03746068 |
| 5 | MP0001666_abnormal_nutrient_absorption | 3.33526917 |
| 6 | MP0004019_abnormal_vitamin_homeostasis | 3.20582446 |
| 7 | MP0005379_endocrine/exocrine_gland_phen | 3.05923122 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.81579037 |
| 9 | MP0005085_abnormal_gallbladder_physiolo | 2.61436954 |
| 10 | MP0009379_abnormal_foot_pigmentation | 2.54904660 |
| 11 | MP0004264_abnormal_extraembryonic_tissu | 2.43921362 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.21523572 |
| 13 | MP0005365_abnormal_bile_salt | 2.21187601 |
| 14 | MP0010234_abnormal_vibrissa_follicle | 2.16273365 |
| 15 | MP0003195_calcinosis | 2.02333719 |
| 16 | MP0005451_abnormal_body_composition | 1.99797715 |
| 17 | MP0008260_abnormal_autophagy | 1.89993817 |
| 18 | MP0003191_abnormal_cellular_cholesterol | 1.87139622 |
| 19 | MP0001764_abnormal_homeostasis | 1.87138444 |
| 20 | MP0010155_abnormal_intestine_physiology | 1.86383279 |
| 21 | MP0009785_altered_susceptibility_to | 1.84455183 |
| 22 | MP0000613_abnormal_salivary_gland | 1.79242023 |
| 23 | MP0004147_increased_porphyrin_level | 1.77676975 |
| 24 | MP0002277_abnormal_respiratory_mucosa | 1.74419119 |
| 25 | MP0008872_abnormal_physiological_respon | 1.70990241 |
| 26 | MP0003252_abnormal_bile_duct | 1.67649648 |
| 27 | MP0006082_CNS_inflammation | 1.53823412 |
| 28 | MP0001756_abnormal_urination | 1.53090086 |
| 29 | MP0005220_abnormal_exocrine_pancreas | 1.48537324 |
| 30 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.46554105 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.35739315 |
| 32 | MP0005332_abnormal_amino_acid | 1.33975150 |
| 33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.33562469 |
| 34 | MP0002796_impaired_skin_barrier | 1.31409787 |
| 35 | MP0009840_abnormal_foam_cell | 1.31070367 |
| 36 | MP0003724_increased_susceptibility_to | 1.30664110 |
| 37 | MP0003866_abnormal_defecation | 1.30325086 |
| 38 | MP0002089_abnormal_postnatal_growth/wei | 1.29472257 |
| 39 | MP0003959_abnormal_lean_body | 1.28574925 |
| 40 | MP0009643_abnormal_urine_homeostasis | 1.26880939 |
| 41 | MP0006054_spinal_hemorrhage | 1.25892549 |
| 42 | MP0005319_abnormal_enzyme/_coenzyme | 1.24927849 |
| 43 | MP0000538_abnormal_urinary_bladder | 1.22323427 |
| 44 | MP0004957_abnormal_blastocyst_morpholog | 1.21319008 |
| 45 | MP0005166_decreased_susceptibility_to | 1.21296014 |
| 46 | MP0001845_abnormal_inflammatory_respons | 1.13390790 |
| 47 | MP0001873_stomach_inflammation | 1.11824147 |
| 48 | MP0002148_abnormal_hypersensitivity_rea | 1.09659738 |
| 49 | MP0005058_abnormal_lysosome_morphology | 1.08870986 |
| 50 | MP0000490_abnormal_crypts_of | 1.08073273 |
| 51 | MP0005025_abnormal_response_to | 1.08055144 |
| 52 | MP0008469_abnormal_protein_level | 1.07866427 |
| 53 | MP0009764_decreased_sensitivity_to | 1.07570123 |
| 54 | MP0001664_abnormal_digestion | 1.04608002 |
| 55 | MP0010386_abnormal_urinary_bladder | 1.04201214 |
| 56 | MP0003300_gastrointestinal_ulcer | 1.03954362 |
| 57 | MP0000537_abnormal_urethra_morphology | 1.03384284 |
| 58 | MP0005670_abnormal_white_adipose | 1.02321566 |
| 59 | MP0002822_catalepsy | 1.01196003 |
| 60 | MP0001765_abnormal_ion_homeostasis | 1.01157278 |
| 61 | MP0005636_abnormal_mineral_homeostasis | 1.00808978 |
| 62 | MP0002138_abnormal_hepatobiliary_system | 1.00595859 |
| 63 | MP0001800_abnormal_humoral_immune | 0.98518145 |
| 64 | MP0001663_abnormal_digestive_system | 0.96791119 |
| 65 | MP0003718_maternal_effect | 0.95634444 |
| 66 | MP0010329_abnormal_lipoprotein_level | 0.95611208 |
| 67 | MP0008004_abnormal_stomach_pH | 0.91296955 |
| 68 | MP0001835_abnormal_antigen_presentation | 0.88542902 |
| 69 | MP0002736_abnormal_nociception_after | 0.88509263 |
| 70 | MP0002136_abnormal_kidney_physiology | 0.87285693 |
| 71 | MP0003186_abnormal_redox_activity | 0.87105182 |
| 72 | MP0002102_abnormal_ear_morphology | 0.84419372 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.84185464 |
| 74 | MP0003315_abnormal_perineum_morphology | 0.82087067 |
| 75 | MP0000477_abnormal_intestine_morphology | 0.81871687 |
| 76 | MP0000858_altered_metastatic_potential | 0.79622446 |
| 77 | MP0002452_abnormal_antigen_presenting | 0.79334702 |
| 78 | MP0002723_abnormal_immune_serum | 0.78659722 |
| 79 | MP0010352_gastrointestinal_tract_polyps | 0.77396433 |
| 80 | MP0005408_hypopigmentation | 0.74502477 |
| 81 | MP0000609_abnormal_liver_physiology | 0.70609083 |
| 82 | MP0005000_abnormal_immune_tolerance | 0.68558786 |
| 83 | MP0005376_homeostasis/metabolism_phenot | 0.67357176 |
| 84 | MP0002118_abnormal_lipid_homeostasis | 0.65784743 |
| 85 | MP0001819_abnormal_immune_cell | 0.64621228 |
| 86 | MP0001853_heart_inflammation | 0.64383034 |
| 87 | MP0003878_abnormal_ear_physiology | 0.64007111 |
| 88 | MP0005377_hearing/vestibular/ear_phenot | 0.64007111 |
| 89 | MP0002166_altered_tumor_susceptibility | 0.63952991 |
| 90 | MP0000516_abnormal_urinary_system | 0.63242883 |
| 91 | MP0005367_renal/urinary_system_phenotyp | 0.63242883 |
| 92 | MP0002420_abnormal_adaptive_immunity | 0.62182146 |
| 93 | MP0006036_abnormal_mitochondrial_physio | 0.61777413 |
| 94 | MP0005666_abnormal_adipose_tissue | 0.61712351 |
| 95 | MP0000015_abnormal_ear_pigmentation | 0.60833226 |
| 96 | MP0005381_digestive/alimentary_phenotyp | 0.59809848 |
| 97 | MP0005501_abnormal_skin_physiology | 0.59804120 |
| 98 | MP0002006_tumorigenesis | 0.59754758 |
| 99 | MP0002419_abnormal_innate_immunity | 0.58795288 |
| 100 | MP0005167_abnormal_blood-brain_barrier | 0.58266289 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of liposaccharide metabolism (HP:0010968) | 6.44681864 |
| 2 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 6.44681864 |
| 3 | Abnormality of glycolipid metabolism (HP:0010969) | 6.44681864 |
| 4 | J-shaped sella turcica (HP:0002680) | 6.19781467 |
| 5 | Carpal bone hypoplasia (HP:0001498) | 5.13786451 |
| 6 | Vertebral arch anomaly (HP:0008438) | 4.87814979 |
| 7 | Diastasis recti (HP:0001540) | 4.59940110 |
| 8 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.02250080 |
| 9 | Thoracolumbar scoliosis (HP:0002944) | 3.95423122 |
| 10 | Flat acetabular roof (HP:0003180) | 3.88352862 |
| 11 | Abnormality of the lumbar spine (HP:0100712) | 3.75104068 |
| 12 | Nausea (HP:0002018) | 3.74089129 |
| 13 | Deformed sella turcica (HP:0002681) | 3.65757988 |
| 14 | Mucopolysacchariduria (HP:0008155) | 3.64388301 |
| 15 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.64388301 |
| 16 | Beaking of vertebral bodies (HP:0004568) | 3.61744934 |
| 17 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.54364913 |
| 18 | Dysostosis multiplex (HP:0000943) | 3.53926032 |
| 19 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.44454054 |
| 20 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.44454054 |
| 21 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.44454054 |
| 22 | Flared iliac wings (HP:0002869) | 3.42183881 |
| 23 | Broad alveolar ridges (HP:0000187) | 3.19806186 |
| 24 | Thoracic kyphosis (HP:0002942) | 3.18056730 |
| 25 | Recurrent bronchitis (HP:0002837) | 3.14632824 |
| 26 | Orthostatic hypotension (HP:0001278) | 3.01402407 |
| 27 | Abnormality of proline metabolism (HP:0010907) | 2.89733423 |
| 28 | Hydroxyprolinuria (HP:0003080) | 2.89733423 |
| 29 | Death in childhood (HP:0003819) | 2.76117959 |
| 30 | Tongue fasciculations (HP:0001308) | 2.73400957 |
| 31 | Broad ribs (HP:0000885) | 2.73015002 |
| 32 | Aortic regurgitation (HP:0001659) | 2.66236242 |
| 33 | Protuberant abdomen (HP:0001538) | 2.62815192 |
| 34 | Thickened calvaria (HP:0002684) | 2.60180166 |
| 35 | Fat malabsorption (HP:0002630) | 2.59821225 |
| 36 | Malnutrition (HP:0004395) | 2.59411371 |
| 37 | Abnormality of the sella turcica (HP:0002679) | 2.57985816 |
| 38 | Hepatocellular necrosis (HP:0001404) | 2.45331858 |
| 39 | Ileus (HP:0002595) | 2.44736339 |
| 40 | Hepatic necrosis (HP:0002605) | 2.43365422 |
| 41 | Abdominal distention (HP:0003270) | 2.41407312 |
| 42 | Abnormality of urine glucose concentration (HP:0011016) | 2.40021273 |
| 43 | Glycosuria (HP:0003076) | 2.40021273 |
| 44 | Proximal tubulopathy (HP:0000114) | 2.35257520 |
| 45 | Mitochondrial inheritance (HP:0001427) | 2.30543096 |
| 46 | Muscle fibrillation (HP:0010546) | 2.28753218 |
| 47 | Pathologic fracture (HP:0002756) | 2.18784095 |
| 48 | Type I transferrin isoform profile (HP:0003642) | 2.12588755 |
| 49 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.12513824 |
| 50 | Progressive neurologic deterioration (HP:0002344) | 2.12473931 |
| 51 | Prolonged neonatal jaundice (HP:0006579) | 2.11526701 |
| 52 | Hypoplasia of the odontoid process (HP:0003311) | 2.09786106 |
| 53 | Microretrognathia (HP:0000308) | 2.09549869 |
| 54 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.09371881 |
| 55 | Chronic diarrhea (HP:0002028) | 2.08515895 |
| 56 | Acute necrotizing encephalopathy (HP:0006965) | 2.07931984 |
| 57 | Increased CSF lactate (HP:0002490) | 2.07722297 |
| 58 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.07430351 |
| 59 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.07430351 |
| 60 | Recurrent pneumonia (HP:0006532) | 2.04859842 |
| 61 | Renal tubular acidosis (HP:0001947) | 2.04784148 |
| 62 | Abnormality of the thoracic spine (HP:0100711) | 2.04272995 |
| 63 | Abnormality of the alveolar ridges (HP:0006477) | 2.03481525 |
| 64 | Slow saccadic eye movements (HP:0000514) | 1.99287173 |
| 65 | Acute encephalopathy (HP:0006846) | 1.97788178 |
| 66 | Anomalous pulmonary venous return (HP:0010772) | 1.97060962 |
| 67 | Pancreatitis (HP:0001733) | 1.95660702 |
| 68 | Vascular calcification (HP:0004934) | 1.95211007 |
| 69 | Steatorrhea (HP:0002570) | 1.94611854 |
| 70 | Systemic lupus erythematosus (HP:0002725) | 1.94187115 |
| 71 | Abnormality of the odontoid process (HP:0003310) | 1.93494088 |
| 72 | Bronchitis (HP:0012387) | 1.92976089 |
| 73 | Dysautonomia (HP:0002459) | 1.91037183 |
| 74 | Wide intermamillary distance (HP:0006610) | 1.90985690 |
| 75 | Late onset (HP:0003584) | 1.88392650 |
| 76 | Severe global developmental delay (HP:0011344) | 1.85888783 |
| 77 | Lethargy (HP:0001254) | 1.82962288 |
| 78 | Rough bone trabeculation (HP:0100670) | 1.82695743 |
| 79 | Ovoid vertebral bodies (HP:0003300) | 1.81240713 |
| 80 | Hypobetalipoproteinemia (HP:0003563) | 1.80173010 |
| 81 | Increased muscle lipid content (HP:0009058) | 1.80143653 |
| 82 | Cerebral edema (HP:0002181) | 1.79407296 |
| 83 | Abnormality of the pulmonary veins (HP:0011718) | 1.77871447 |
| 84 | Hoarse voice (HP:0001609) | 1.76531019 |
| 85 | Abnormal trabecular bone morphology (HP:0100671) | 1.76332491 |
| 86 | Increased intramyocellular lipid droplets (HP:0012240) | 1.75681485 |
| 87 | Intrahepatic cholestasis (HP:0001406) | 1.75457426 |
| 88 | Renal tubular dysfunction (HP:0000124) | 1.75005692 |
| 89 | Amyloidosis (HP:0011034) | 1.73365711 |
| 90 | Dicarboxylic aciduria (HP:0003215) | 1.71593816 |
| 91 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.71593816 |
| 92 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.69427076 |
| 93 | Acne (HP:0001061) | 1.69411616 |
| 94 | Hypotension (HP:0002615) | 1.69358517 |
| 95 | Palpebral edema (HP:0100540) | 1.68848302 |
| 96 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.66384727 |
| 97 | Lactic acidosis (HP:0003128) | 1.65045371 |
| 98 | Hyperuricemia (HP:0002149) | 1.64728481 |
| 99 | Increased purine levels (HP:0004368) | 1.64728481 |
| 100 | Conjugated hyperbilirubinemia (HP:0002908) | 1.63980153 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA2 | 4.07148146 |
| 2 | BLK | 3.92323533 |
| 3 | GRK6 | 3.08466601 |
| 4 | CAMKK2 | 2.83412565 |
| 5 | MST4 | 2.78442307 |
| 6 | TESK1 | 2.77468269 |
| 7 | TESK2 | 2.74620728 |
| 8 | VRK2 | 2.60084970 |
| 9 | ACVR1B | 2.58088579 |
| 10 | NME2 | 2.57402655 |
| 11 | MST1R | 2.55269312 |
| 12 | TAF1 | 2.52463046 |
| 13 | MAP3K12 | 2.44608325 |
| 14 | PDK2 | 2.14776203 |
| 15 | BCKDK | 2.03778007 |
| 16 | LMTK2 | 1.87685045 |
| 17 | ERN1 | 1.73578729 |
| 18 | SCYL2 | 1.66363004 |
| 19 | BUB1 | 1.58421522 |
| 20 | EIF2AK1 | 1.55910445 |
| 21 | TBK1 | 1.55910303 |
| 22 | RIPK1 | 1.44431073 |
| 23 | GRK5 | 1.43360647 |
| 24 | FRK | 1.42622917 |
| 25 | BRSK2 | 1.40283230 |
| 26 | MAP3K3 | 1.39468292 |
| 27 | TXK | 1.39029179 |
| 28 | NME1 | 1.36818202 |
| 29 | RIPK4 | 1.34089567 |
| 30 | RPS6KB2 | 1.34002302 |
| 31 | TYK2 | 1.33880750 |
| 32 | IKBKE | 1.29495509 |
| 33 | IRAK3 | 1.28400415 |
| 34 | STK4 | 1.28226401 |
| 35 | KDR | 1.22656734 |
| 36 | ABL2 | 1.20555453 |
| 37 | PBK | 1.18199434 |
| 38 | IRAK2 | 1.16769375 |
| 39 | TLK1 | 1.13346803 |
| 40 | DAPK1 | 1.09572829 |
| 41 | MAP3K2 | 1.08857793 |
| 42 | LIMK1 | 1.05922465 |
| 43 | PAK4 | 1.03132566 |
| 44 | PTK2B | 1.02556814 |
| 45 | BRSK1 | 0.97870355 |
| 46 | VRK1 | 0.97138047 |
| 47 | MYLK | 0.94230567 |
| 48 | MAP3K11 | 0.86280272 |
| 49 | PRPF4B | 0.85035617 |
| 50 | DAPK3 | 0.84918393 |
| 51 | GRK1 | 0.84046381 |
| 52 | PRKG2 | 0.81407544 |
| 53 | PIM2 | 0.78510005 |
| 54 | TAOK2 | 0.76173301 |
| 55 | CAMK4 | 0.76026970 |
| 56 | MAP3K1 | 0.74175443 |
| 57 | MATK | 0.73276294 |
| 58 | IKBKB | 0.68906121 |
| 59 | BMPR2 | 0.68143622 |
| 60 | TAOK3 | 0.67668032 |
| 61 | RPS6KA4 | 0.66410765 |
| 62 | IRAK4 | 0.65471633 |
| 63 | STK16 | 0.60443474 |
| 64 | MAP2K3 | 0.59762160 |
| 65 | FGR | 0.58447361 |
| 66 | AURKB | 0.57499845 |
| 67 | DAPK2 | 0.56703856 |
| 68 | IRAK1 | 0.55636737 |
| 69 | CAMK2D | 0.55618441 |
| 70 | STK10 | 0.55574071 |
| 71 | PIM1 | 0.54402927 |
| 72 | CAMK2G | 0.53910253 |
| 73 | MAP4K2 | 0.53094627 |
| 74 | CAMK2B | 0.52944062 |
| 75 | TNIK | 0.50172564 |
| 76 | YES1 | 0.49350993 |
| 77 | OXSR1 | 0.47777659 |
| 78 | RPS6KA5 | 0.46992491 |
| 79 | FES | 0.45275862 |
| 80 | TRIM28 | 0.44064511 |
| 81 | LYN | 0.43357793 |
| 82 | ADRBK1 | 0.43311789 |
| 83 | CSNK1G3 | 0.43151331 |
| 84 | MET | 0.43067296 |
| 85 | MAP3K8 | 0.42247908 |
| 86 | ADRBK2 | 0.41549141 |
| 87 | CSNK1A1L | 0.39760330 |
| 88 | EIF2AK3 | 0.39582781 |
| 89 | ZAK | 0.37847726 |
| 90 | LRRK2 | 0.37540328 |
| 91 | MAP2K2 | 0.37187197 |
| 92 | CDK19 | 0.37067839 |
| 93 | GRK7 | 0.35985673 |
| 94 | PLK1 | 0.34948627 |
| 95 | CHUK | 0.33284315 |
| 96 | FER | 0.33161884 |
| 97 | SYK | 0.29141617 |
| 98 | PRKCA | 0.26127376 |
| 99 | CSNK1A1 | 0.25960500 |
| 100 | STK39 | 0.25780678 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 6.99458966 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.76206683 |
| 3 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.87530340 |
| 4 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.78859332 |
| 5 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.58182891 |
| 6 | Glutathione metabolism_Homo sapiens_hsa00480 | 2.56790307 |
| 7 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 2.31473928 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.05251469 |
| 9 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.98837253 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 1.88137457 |
| 11 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.87731152 |
| 12 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.75237372 |
| 13 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.68353271 |
| 14 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.62130667 |
| 15 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.59746561 |
| 16 | Galactose metabolism_Homo sapiens_hsa00052 | 1.59468656 |
| 17 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.57540664 |
| 18 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.56066393 |
| 19 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.51093742 |
| 20 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.38938273 |
| 21 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.35834206 |
| 22 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.32248205 |
| 23 | Mineral absorption_Homo sapiens_hsa04978 | 1.32221372 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.29313026 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.27851740 |
| 26 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.24987719 |
| 27 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.23760810 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.22882030 |
| 29 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.22293197 |
| 30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.19401091 |
| 31 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.18792431 |
| 32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.11937836 |
| 33 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.11557145 |
| 34 | DNA replication_Homo sapiens_hsa03030 | 1.11087865 |
| 35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.08965439 |
| 36 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.07012460 |
| 37 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05883568 |
| 38 | Asthma_Homo sapiens_hsa05310 | 1.02657780 |
| 39 | Histidine metabolism_Homo sapiens_hsa00340 | 0.97020227 |
| 40 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.95794745 |
| 41 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.94330568 |
| 42 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.94261796 |
| 43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.93945957 |
| 44 | Sulfur relay system_Homo sapiens_hsa04122 | 0.93263818 |
| 45 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.92445353 |
| 46 | Ribosome_Homo sapiens_hsa03010 | 0.92259966 |
| 47 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.92259701 |
| 48 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.90992542 |
| 49 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.90824947 |
| 50 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.89684197 |
| 51 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.89662902 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.86705954 |
| 53 | RNA polymerase_Homo sapiens_hsa03020 | 0.84252428 |
| 54 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.83484737 |
| 55 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.83079730 |
| 56 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.83067217 |
| 57 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.82983979 |
| 58 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.80833938 |
| 59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76474315 |
| 60 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.74399593 |
| 61 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74395044 |
| 62 | Mismatch repair_Homo sapiens_hsa03430 | 0.72383023 |
| 63 | Lysosome_Homo sapiens_hsa04142 | 0.71033188 |
| 64 | Leishmaniasis_Homo sapiens_hsa05140 | 0.70290245 |
| 65 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.67620564 |
| 66 | Peroxisome_Homo sapiens_hsa04146 | 0.65773422 |
| 67 | Carbon metabolism_Homo sapiens_hsa01200 | 0.65200488 |
| 68 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.64624470 |
| 69 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.64421176 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.63532995 |
| 71 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.62554052 |
| 72 | Tuberculosis_Homo sapiens_hsa05152 | 0.62178587 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61568363 |
| 74 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.61047391 |
| 75 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.57662910 |
| 76 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.56899485 |
| 77 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.54906043 |
| 78 | Base excision repair_Homo sapiens_hsa03410 | 0.53284973 |
| 79 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.53109086 |
| 80 | Purine metabolism_Homo sapiens_hsa00230 | 0.52443680 |
| 81 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.49346236 |
| 82 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.47494745 |
| 83 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43557242 |
| 84 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.43459216 |
| 85 | Hepatitis C_Homo sapiens_hsa05160 | 0.43150995 |
| 86 | Alcoholism_Homo sapiens_hsa05034 | 0.41346591 |
| 87 | Protein export_Homo sapiens_hsa03060 | 0.40787031 |
| 88 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.40356155 |
| 89 | Legionellosis_Homo sapiens_hsa05134 | 0.39935508 |
| 90 | Allograft rejection_Homo sapiens_hsa05330 | 0.39758779 |
| 91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.39202337 |
| 92 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.38351767 |
| 93 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.36820351 |
| 94 | Bile secretion_Homo sapiens_hsa04976 | 0.34468525 |
| 95 | Salmonella infection_Homo sapiens_hsa05132 | 0.34369038 |
| 96 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.33580457 |
| 97 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.33485887 |
| 98 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.32740518 |
| 99 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.31402829 |
| 100 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.31214160 |

