

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of odontogenesis (GO:0042482) | 4.90014095 |
| 2 | homocysteine metabolic process (GO:0050667) | 4.69909949 |
| 3 | cellular response to epinephrine stimulus (GO:0071872) | 4.57426257 |
| 4 | regulation of relaxation of muscle (GO:1901077) | 4.52715321 |
| 5 | urea cycle (GO:0000050) | 4.46360196 |
| 6 | atrioventricular valve morphogenesis (GO:0003181) | 4.38186268 |
| 7 | midgut development (GO:0007494) | 4.23610050 |
| 8 | regulation of vitamin metabolic process (GO:0030656) | 4.09012562 |
| 9 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 4.08605626 |
| 10 | urea metabolic process (GO:0019627) | 3.95475634 |
| 11 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.94210153 |
| 12 | positive regulation of heat generation (GO:0031652) | 3.93546275 |
| 13 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.93001509 |
| 14 | citrulline biosynthetic process (GO:0019240) | 3.84460642 |
| 15 | positive regulation of p38MAPK cascade (GO:1900745) | 3.78794623 |
| 16 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.78379546 |
| 17 | response to peptidoglycan (GO:0032494) | 3.77997372 |
| 18 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.76214771 |
| 19 | T-helper 1 type immune response (GO:0042088) | 3.75445654 |
| 20 | neutrophil activation involved in immune response (GO:0002283) | 3.73125768 |
| 21 | germinal center formation (GO:0002467) | 3.73034780 |
| 22 | glycolipid catabolic process (GO:0019377) | 3.68885512 |
| 23 | regulation of fever generation (GO:0031620) | 3.68298267 |
| 24 | detection of molecule of bacterial origin (GO:0032490) | 3.63139782 |
| 25 | response to epinephrine (GO:0071871) | 3.59642947 |
| 26 | neutrophil chemotaxis (GO:0030593) | 3.57336286 |
| 27 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.55831168 |
| 28 | negative regulation of complement activation (GO:0045916) | 3.49938941 |
| 29 | nitrogen cycle metabolic process (GO:0071941) | 3.48786020 |
| 30 | cAMP catabolic process (GO:0006198) | 3.48195705 |
| 31 | hepatocyte differentiation (GO:0070365) | 3.47686715 |
| 32 | neutrophil migration (GO:1990266) | 3.47244775 |
| 33 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.37165118 |
| 34 | glycosphingolipid catabolic process (GO:0046479) | 3.34071025 |
| 35 | response to laminar fluid shear stress (GO:0034616) | 3.28820069 |
| 36 | cyclooxygenase pathway (GO:0019371) | 3.20320534 |
| 37 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.19133939 |
| 38 | low-density lipoprotein particle clearance (GO:0034383) | 3.18664232 |
| 39 | negative regulation of interleukin-12 production (GO:0032695) | 3.16711293 |
| 40 | cellular extravasation (GO:0045123) | 3.16409067 |
| 41 | cellular response to arsenic-containing substance (GO:0071243) | 3.15634379 |
| 42 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.15431751 |
| 43 | granulocyte activation (GO:0036230) | 3.15031829 |
| 44 | negative regulation of alcohol biosynthetic process (GO:1902931) | 3.14732351 |
| 45 | macrophage activation (GO:0042116) | 3.13978476 |
| 46 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.11392224 |
| 47 | negative regulation of protein activation cascade (GO:2000258) | 3.09379217 |
| 48 | positive regulation of osteoblast proliferation (GO:0033690) | 3.07242563 |
| 49 | granulocyte chemotaxis (GO:0071621) | 3.06665435 |
| 50 | citrulline metabolic process (GO:0000052) | 3.03800719 |
| 51 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.03792332 |
| 52 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.00757484 |
| 53 | iron ion import (GO:0097286) | 2.99070731 |
| 54 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.97800821 |
| 55 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.97639633 |
| 56 | GDP-mannose metabolic process (GO:0019673) | 2.97231869 |
| 57 | amyloid precursor protein catabolic process (GO:0042987) | 2.93087064 |
| 58 | energy homeostasis (GO:0097009) | 2.91867527 |
| 59 | granulocyte migration (GO:0097530) | 2.91694846 |
| 60 | cyclic nucleotide catabolic process (GO:0009214) | 2.90931636 |
| 61 | macrophage activation involved in immune response (GO:0002281) | 2.90634107 |
| 62 | neutrophil activation (GO:0042119) | 2.89619918 |
| 63 | positive regulation of acute inflammatory response (GO:0002675) | 2.86207853 |
| 64 | oligosaccharide catabolic process (GO:0009313) | 2.83813551 |
| 65 | positive regulation of pseudopodium assembly (GO:0031274) | 2.83382792 |
| 66 | establishment of endothelial barrier (GO:0061028) | 2.82147265 |
| 67 | trophoblast giant cell differentiation (GO:0060707) | 2.81223857 |
| 68 | xenobiotic catabolic process (GO:0042178) | 2.80941845 |
| 69 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.80666520 |
| 70 | NIK/NF-kappaB signaling (GO:0038061) | 2.78542721 |
| 71 | regulation of glucocorticoid metabolic process (GO:0031943) | 2.75359799 |
| 72 | ER overload response (GO:0006983) | 2.74894017 |
| 73 | modulation by symbiont of host defense response (GO:0052031) | 2.74888080 |
| 74 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.74888080 |
| 75 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.74888080 |
| 76 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.74888080 |
| 77 | modulation by symbiont of host immune response (GO:0052553) | 2.74888080 |
| 78 | positive regulation by symbiont of host defense response (GO:0052509) | 2.74888080 |
| 79 | embryonic process involved in female pregnancy (GO:0060136) | 2.73533810 |
| 80 | negative regulation of humoral immune response (GO:0002921) | 2.72349045 |
| 81 | renal absorption (GO:0070293) | 2.71642158 |
| 82 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 2.70589345 |
| 83 | membrane lipid catabolic process (GO:0046466) | 2.70063648 |
| 84 | positive regulation of nitric oxide biosynthetic process (GO:0045429) | 2.68791667 |
| 85 | prostanoid biosynthetic process (GO:0046457) | 2.68640463 |
| 86 | prostaglandin biosynthetic process (GO:0001516) | 2.68640463 |
| 87 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.67706491 |
| 88 | regulation of actin filament-based movement (GO:1903115) | 2.66584562 |
| 89 | positive regulation of astrocyte differentiation (GO:0048711) | 2.66548226 |
| 90 | regulation of heat generation (GO:0031650) | 2.66414221 |
| 91 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.64750446 |
| 92 | negative regulation of B cell mediated immunity (GO:0002713) | 2.64637481 |
| 93 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.64637481 |
| 94 | immunoglobulin mediated immune response (GO:0016064) | 2.63846457 |
| 95 | regulation of chemokine biosynthetic process (GO:0045073) | 2.60240744 |
| 96 | neutrophil mediated immunity (GO:0002446) | 2.59570691 |
| 97 | basement membrane organization (GO:0071711) | 2.58162860 |
| 98 | antimicrobial humoral response (GO:0019730) | 2.56478356 |
| 99 | positive regulation of leukocyte apoptotic process (GO:2000108) | 2.55227018 |
| 100 | regulation of NF-kappaB import into nucleus (GO:0042345) | 2.54173798 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.17771869 |
| 2 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 5.14194623 |
| 3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.96627824 |
| 4 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.92173720 |
| 5 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.38753999 |
| 6 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.31542522 |
| 7 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.26314945 |
| 8 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.26162249 |
| 9 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.19210363 |
| 10 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.18001066 |
| 11 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.15270138 |
| 12 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.03994964 |
| 13 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.01561024 |
| 14 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.00439119 |
| 15 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.84310389 |
| 16 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.84003537 |
| 17 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.82030963 |
| 18 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.80076982 |
| 19 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.76010646 |
| 20 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.75706274 |
| 21 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.73265990 |
| 22 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.72068172 |
| 23 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.71302757 |
| 24 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.70590522 |
| 25 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.67167321 |
| 26 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.62137322 |
| 27 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.59833669 |
| 28 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.56037919 |
| 29 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.53981080 |
| 30 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.53866828 |
| 31 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.53312901 |
| 32 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.52646861 |
| 33 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.52305301 |
| 34 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.51717961 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.48258161 |
| 36 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.47184520 |
| 37 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.46042137 |
| 38 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.44869617 |
| 39 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.43866924 |
| 40 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.43467679 |
| 41 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.41511783 |
| 42 | ATF3_27146783_Chip-Seq_COLON_Human | 1.39560318 |
| 43 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.39412891 |
| 44 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.37987028 |
| 45 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.34645890 |
| 46 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.33653319 |
| 47 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31839415 |
| 48 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.31771649 |
| 49 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.29681814 |
| 50 | MAF_26560356_Chip-Seq_TH1_Human | 1.28798971 |
| 51 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27966763 |
| 52 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.27330746 |
| 53 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.27085541 |
| 54 | MYC_22102868_ChIP-Seq_BL_Human | 1.27008007 |
| 55 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.26797439 |
| 56 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.26639929 |
| 57 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.23662951 |
| 58 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.23033310 |
| 59 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.21925924 |
| 60 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.20025042 |
| 61 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.19962803 |
| 62 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.18562585 |
| 63 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.17917506 |
| 64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.17565725 |
| 65 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.17445737 |
| 66 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.15695378 |
| 67 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.15572526 |
| 68 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.13369950 |
| 69 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.11547257 |
| 70 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.11176725 |
| 71 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.10907910 |
| 72 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.08380841 |
| 73 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.08061811 |
| 74 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.05786801 |
| 75 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.05198899 |
| 76 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.04907607 |
| 77 | GATA1_22025678_ChIP-Seq_K562_Human | 1.04699957 |
| 78 | UTX_26944678_Chip-Seq_JUKART_Human | 1.04420059 |
| 79 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.04416314 |
| 80 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04347949 |
| 81 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.04325390 |
| 82 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04183025 |
| 83 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.02413900 |
| 84 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.02378242 |
| 85 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02352570 |
| 86 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.01613854 |
| 87 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.00890547 |
| 88 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.00405971 |
| 89 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.00276556 |
| 90 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.99857335 |
| 91 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.99322601 |
| 92 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.99203878 |
| 93 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.99116479 |
| 94 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.98873140 |
| 95 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.98257476 |
| 96 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.98257476 |
| 97 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.97844485 |
| 98 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.96571000 |
| 99 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.95605499 |
| 100 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.95505007 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 5.88950772 |
| 2 | MP0003724_increased_susceptibility_to | 4.77199136 |
| 3 | MP0005083_abnormal_biliary_tract | 4.01857618 |
| 4 | MP0008004_abnormal_stomach_pH | 3.91872190 |
| 5 | MP0005451_abnormal_body_composition | 3.47791773 |
| 6 | MP0009840_abnormal_foam_cell | 2.91437512 |
| 7 | MP0009278_abnormal_bone_marrow | 2.83324292 |
| 8 | MP0002139_abnormal_hepatobiliary_system | 2.70052838 |
| 9 | MP0003436_decreased_susceptibility_to | 2.61288215 |
| 10 | MP0005058_abnormal_lysosome_morphology | 2.57653729 |
| 11 | MP0010352_gastrointestinal_tract_polyps | 2.36712507 |
| 12 | MP0009764_decreased_sensitivity_to | 2.11410578 |
| 13 | MP0005085_abnormal_gallbladder_physiolo | 2.10638193 |
| 14 | MP0010234_abnormal_vibrissa_follicle | 2.04374982 |
| 15 | MP0003075_altered_response_to | 2.03069610 |
| 16 | MP0005360_urolithiasis | 1.93689307 |
| 17 | MP0006082_CNS_inflammation | 1.93595905 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 1.90136249 |
| 19 | MP0002419_abnormal_innate_immunity | 1.88844506 |
| 20 | MP0008260_abnormal_autophagy | 1.86096704 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.70143833 |
| 22 | MP0005076_abnormal_cell_differentiation | 1.64080252 |
| 23 | MP0001533_abnormal_skeleton_physiology | 1.63544383 |
| 24 | MP0001835_abnormal_antigen_presentation | 1.55920600 |
| 25 | MP0009785_altered_susceptibility_to | 1.54445836 |
| 26 | MP0008875_abnormal_xenobiotic_pharmacok | 1.53960280 |
| 27 | MP0004233_abnormal_muscle_weight | 1.52953181 |
| 28 | MP0005166_decreased_susceptibility_to | 1.51957690 |
| 29 | MP0005000_abnormal_immune_tolerance | 1.50375955 |
| 30 | MP0010155_abnormal_intestine_physiology | 1.45876036 |
| 31 | MP0005319_abnormal_enzyme/_coenzyme | 1.43330833 |
| 32 | MP0001853_heart_inflammation | 1.43242330 |
| 33 | MP0001545_abnormal_hematopoietic_system | 1.42470500 |
| 34 | MP0005397_hematopoietic_system_phenotyp | 1.42470500 |
| 35 | MP0005167_abnormal_blood-brain_barrier | 1.41666310 |
| 36 | MP0005025_abnormal_response_to | 1.39912198 |
| 37 | MP0005365_abnormal_bile_salt | 1.36959110 |
| 38 | MP0003453_abnormal_keratinocyte_physiol | 1.34870384 |
| 39 | MP0008469_abnormal_protein_level | 1.34322848 |
| 40 | MP0002723_abnormal_immune_serum | 1.30548315 |
| 41 | MP0004947_skin_inflammation | 1.30270740 |
| 42 | MP0003693_abnormal_embryo_hatching | 1.28659258 |
| 43 | MP0006054_spinal_hemorrhage | 1.26687947 |
| 44 | MP0000490_abnormal_crypts_of | 1.25067503 |
| 45 | MP0001764_abnormal_homeostasis | 1.24773264 |
| 46 | MP0004808_abnormal_hematopoietic_stem | 1.24086878 |
| 47 | MP0003191_abnormal_cellular_cholesterol | 1.23276782 |
| 48 | MP0001845_abnormal_inflammatory_respons | 1.22202821 |
| 49 | MP0009333_abnormal_splenocyte_physiolog | 1.20207349 |
| 50 | MP0002332_abnormal_exercise_endurance | 1.16776325 |
| 51 | MP0002452_abnormal_antigen_presenting | 1.15953940 |
| 52 | MP0000609_abnormal_liver_physiology | 1.11616047 |
| 53 | MP0004510_myositis | 1.10616173 |
| 54 | MP0001800_abnormal_humoral_immune | 1.08111552 |
| 55 | MP0002132_abnormal_respiratory_system | 1.06719573 |
| 56 | MP0004019_abnormal_vitamin_homeostasis | 1.04672938 |
| 57 | MP0000465_gastrointestinal_hemorrhage | 1.00314832 |
| 58 | MP0001790_abnormal_immune_system | 0.98936774 |
| 59 | MP0005387_immune_system_phenotype | 0.98936774 |
| 60 | MP0001666_abnormal_nutrient_absorption | 0.98495426 |
| 61 | MP0003828_pulmonary_edema | 0.98103748 |
| 62 | MP0005671_abnormal_response_to | 0.98086828 |
| 63 | MP0000858_altered_metastatic_potential | 0.94245695 |
| 64 | MP0000343_altered_response_to | 0.94237725 |
| 65 | MP0001819_abnormal_immune_cell | 0.93226981 |
| 66 | MP0002420_abnormal_adaptive_immunity | 0.93018465 |
| 67 | MP0000003_abnormal_adipose_tissue | 0.92741379 |
| 68 | MP0003448_altered_tumor_morphology | 0.92562146 |
| 69 | MP0004957_abnormal_blastocyst_morpholog | 0.91662231 |
| 70 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.90728277 |
| 71 | MP0002877_abnormal_melanocyte_morpholog | 0.90306316 |
| 72 | MP0005375_adipose_tissue_phenotype | 0.90237786 |
| 73 | MP0002405_respiratory_system_inflammati | 0.87436575 |
| 74 | MP0005334_abnormal_fat_pad | 0.86647633 |
| 75 | MP0005248_abnormal_Harderian_gland | 0.85588404 |
| 76 | MP0002796_impaired_skin_barrier | 0.84270971 |
| 77 | MP0000685_abnormal_immune_system | 0.83452718 |
| 78 | MP0005464_abnormal_platelet_physiology | 0.79338492 |
| 79 | MP0002998_abnormal_bone_remodeling | 0.78579068 |
| 80 | MP0001849_ear_inflammation | 0.77684472 |
| 81 | MP0005332_abnormal_amino_acid | 0.75053738 |
| 82 | MP0005164_abnormal_response_to | 0.73693230 |
| 83 | MP0005666_abnormal_adipose_tissue | 0.73538480 |
| 84 | MP0001663_abnormal_digestive_system | 0.70917678 |
| 85 | MP0000604_amyloidosis | 0.69260800 |
| 86 | MP0000750_abnormal_muscle_regeneration | 0.67340328 |
| 87 | MP0009643_abnormal_urine_homeostasis | 0.67133931 |
| 88 | MP0009765_abnormal_xenobiotic_induced | 0.66345279 |
| 89 | MP0009763_increased_sensitivity_to | 0.64324386 |
| 90 | MP0001216_abnormal_epidermal_layer | 0.64209235 |
| 91 | MP0000716_abnormal_immune_system | 0.63783690 |
| 92 | MP0000598_abnormal_liver_morphology | 0.63268435 |
| 93 | MP0003879_abnormal_hair_cell | 0.63258365 |
| 94 | MP0005165_increased_susceptibility_to | 0.62006340 |
| 95 | MP0002118_abnormal_lipid_homeostasis | 0.61706036 |
| 96 | MP0002089_abnormal_postnatal_growth/wei | 0.61338911 |
| 97 | MP0002429_abnormal_blood_cell | 0.60839259 |
| 98 | MP0003795_abnormal_bone_structure | 0.60728854 |
| 99 | MP0001727_abnormal_embryo_implantation | 0.59580411 |
| 100 | MP0005376_homeostasis/metabolism_phenot | 0.58740142 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.69856629 |
| 2 | Abnormality of glycolipid metabolism (HP:0010969) | 4.51117921 |
| 3 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.51117921 |
| 4 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.51117921 |
| 5 | Malnutrition (HP:0004395) | 4.03492445 |
| 6 | Orchitis (HP:0100796) | 3.94644161 |
| 7 | Vacuolated lymphocytes (HP:0001922) | 3.78105005 |
| 8 | Vascular calcification (HP:0004934) | 3.75900855 |
| 9 | Increased cerebral lipofuscin (HP:0011813) | 3.46503304 |
| 10 | Abnormality of macrophages (HP:0004311) | 3.45361151 |
| 11 | Optic neuritis (HP:0100653) | 3.37774674 |
| 12 | Retrobulbar optic neuritis (HP:0100654) | 3.37774674 |
| 13 | Myositis (HP:0100614) | 3.18707659 |
| 14 | Cardiovascular calcification (HP:0011915) | 3.14694349 |
| 15 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.09619606 |
| 16 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.05176411 |
| 17 | Ragged-red muscle fibers (HP:0003200) | 2.99666164 |
| 18 | Alkalosis (HP:0001948) | 2.98864108 |
| 19 | Abnormality of the nasal septum (HP:0000419) | 2.93148642 |
| 20 | Loss of speech (HP:0002371) | 2.90333684 |
| 21 | Nausea (HP:0002018) | 2.88333725 |
| 22 | Recurrent bacterial skin infections (HP:0005406) | 2.85840243 |
| 23 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.83717958 |
| 24 | Micronodular cirrhosis (HP:0001413) | 2.80428079 |
| 25 | Retinal atrophy (HP:0001105) | 2.79448750 |
| 26 | Microvesicular hepatic steatosis (HP:0001414) | 2.78643881 |
| 27 | Recurrent abscess formation (HP:0002722) | 2.77232105 |
| 28 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.75183529 |
| 29 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.75183529 |
| 30 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.75183529 |
| 31 | Hyperammonemia (HP:0001987) | 2.66364623 |
| 32 | Progressive muscle weakness (HP:0003323) | 2.58191339 |
| 33 | Systemic lupus erythematosus (HP:0002725) | 2.58066973 |
| 34 | Increased serum ferritin (HP:0003281) | 2.51003225 |
| 35 | Amyloidosis (HP:0011034) | 2.48575885 |
| 36 | Mucopolysacchariduria (HP:0008155) | 2.45945909 |
| 37 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.45945909 |
| 38 | Vertebral compression fractures (HP:0002953) | 2.44140351 |
| 39 | Dysostosis multiplex (HP:0000943) | 2.40303800 |
| 40 | Hypobetalipoproteinemia (HP:0003563) | 2.39628538 |
| 41 | Eczematoid dermatitis (HP:0000976) | 2.33384358 |
| 42 | Subacute progressive viral hepatitis (HP:0006572) | 2.31798356 |
| 43 | Sparse lateral eyebrow (HP:0005338) | 2.30597454 |
| 44 | Tetany (HP:0001281) | 2.29634747 |
| 45 | Stomatitis (HP:0010280) | 2.29305441 |
| 46 | Paralysis (HP:0003470) | 2.21820065 |
| 47 | Abnormality of the periventricular white matter (HP:0002518) | 2.21411738 |
| 48 | Myocardial infarction (HP:0001658) | 2.20329183 |
| 49 | Hepatocellular carcinoma (HP:0001402) | 2.18866281 |
| 50 | Episodic fever (HP:0001954) | 2.18645125 |
| 51 | Pathologic fracture (HP:0002756) | 2.17798333 |
| 52 | Petechiae (HP:0000967) | 2.15587836 |
| 53 | Rough bone trabeculation (HP:0100670) | 2.15569932 |
| 54 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.13030658 |
| 55 | Anorexia (HP:0002039) | 2.11599971 |
| 56 | Abnormal trabecular bone morphology (HP:0100671) | 2.11450051 |
| 57 | Progressive neurologic deterioration (HP:0002344) | 2.10334375 |
| 58 | Keratoconjunctivitis sicca (HP:0001097) | 2.08309004 |
| 59 | Elbow flexion contracture (HP:0002987) | 2.07878635 |
| 60 | Nuclear cataract (HP:0100018) | 2.07028195 |
| 61 | Xanthomatosis (HP:0000991) | 2.05890459 |
| 62 | Increased circulating renin level (HP:0000848) | 2.04714599 |
| 63 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.02593190 |
| 64 | Prolonged neonatal jaundice (HP:0006579) | 2.02295185 |
| 65 | Steatorrhea (HP:0002570) | 2.01070497 |
| 66 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.99585126 |
| 67 | Mediastinal lymphadenopathy (HP:0100721) | 1.96822103 |
| 68 | Abnormality of alanine metabolism (HP:0010916) | 1.92985928 |
| 69 | Hyperalaninemia (HP:0003348) | 1.92985928 |
| 70 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.92985928 |
| 71 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.91886958 |
| 72 | Gangrene (HP:0100758) | 1.89834791 |
| 73 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.88757035 |
| 74 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.87784990 |
| 75 | Fat malabsorption (HP:0002630) | 1.84708905 |
| 76 | Hemorrhage of the eye (HP:0011885) | 1.84486673 |
| 77 | Abnormality of the peritoneum (HP:0002585) | 1.82702215 |
| 78 | Stroke (HP:0001297) | 1.82543792 |
| 79 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.81866739 |
| 80 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.81184012 |
| 81 | Autoimmune thrombocytopenia (HP:0001973) | 1.81025398 |
| 82 | Paraparesis (HP:0002385) | 1.80514932 |
| 83 | Renal tubular acidosis (HP:0001947) | 1.80470714 |
| 84 | Keratoconjunctivitis (HP:0001096) | 1.78994158 |
| 85 | Mitral stenosis (HP:0001718) | 1.78766566 |
| 86 | Hepatosplenomegaly (HP:0001433) | 1.77952622 |
| 87 | Abnormality of iron homeostasis (HP:0011031) | 1.77721055 |
| 88 | Elevated alkaline phosphatase (HP:0003155) | 1.76629629 |
| 89 | Hypolipoproteinemia (HP:0010981) | 1.74697559 |
| 90 | Tetraparesis (HP:0002273) | 1.73405062 |
| 91 | Acute hepatic failure (HP:0006554) | 1.72080550 |
| 92 | Ureteral duplication (HP:0000073) | 1.71930374 |
| 93 | Purpura (HP:0000979) | 1.71898692 |
| 94 | Deformed sella turcica (HP:0002681) | 1.71881212 |
| 95 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.71212246 |
| 96 | Irritability (HP:0000737) | 1.70702946 |
| 97 | Abnormality of the costochondral junction (HP:0000919) | 1.68683316 |
| 98 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.68043301 |
| 99 | Abnormality of the Achilles tendon (HP:0005109) | 1.67718447 |
| 100 | Parakeratosis (HP:0001036) | 1.67655221 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PDK2 | 9.08489854 |
| 2 | TLK1 | 3.65086339 |
| 3 | IRAK3 | 3.22617573 |
| 4 | ZAK | 2.93437820 |
| 5 | ERN1 | 2.77245035 |
| 6 | NME2 | 2.61067598 |
| 7 | PIM2 | 2.57882398 |
| 8 | PBK | 2.23919259 |
| 9 | SMG1 | 2.03376690 |
| 10 | MST1R | 1.99690675 |
| 11 | STK39 | 1.99588229 |
| 12 | WNK4 | 1.85571940 |
| 13 | BLK | 1.84726411 |
| 14 | ACVR1B | 1.84028340 |
| 15 | OXSR1 | 1.78836288 |
| 16 | STK16 | 1.74798956 |
| 17 | EPHA2 | 1.66489678 |
| 18 | NEK6 | 1.66162948 |
| 19 | MAP3K3 | 1.66074530 |
| 20 | ICK | 1.63109794 |
| 21 | TAOK2 | 1.56211128 |
| 22 | TESK2 | 1.54879393 |
| 23 | IRAK4 | 1.40068659 |
| 24 | MAP3K14 | 1.37434384 |
| 25 | MAP3K11 | 1.36374601 |
| 26 | TBK1 | 1.29562752 |
| 27 | TAOK1 | 1.21914409 |
| 28 | PAK4 | 1.21889483 |
| 29 | MAP3K1 | 1.14720301 |
| 30 | MAP2K3 | 1.12032396 |
| 31 | IRAK2 | 1.09613568 |
| 32 | IKBKB | 1.08941149 |
| 33 | BMPR2 | 1.05006286 |
| 34 | BUB1 | 1.01814079 |
| 35 | PIM1 | 1.01309660 |
| 36 | RPS6KA5 | 0.98622013 |
| 37 | RIPK1 | 0.92853783 |
| 38 | MAP2K2 | 0.92157865 |
| 39 | MAP4K1 | 0.92147168 |
| 40 | PDPK1 | 0.86206000 |
| 41 | MATK | 0.85606894 |
| 42 | LATS2 | 0.85594130 |
| 43 | RPS6KB2 | 0.81399636 |
| 44 | RAF1 | 0.78862999 |
| 45 | ABL2 | 0.78647525 |
| 46 | ZAP70 | 0.77357942 |
| 47 | TXK | 0.76655407 |
| 48 | SIK1 | 0.76234447 |
| 49 | IRAK1 | 0.74139578 |
| 50 | IKBKE | 0.70673471 |
| 51 | JAK2 | 0.70071722 |
| 52 | CSK | 0.68957388 |
| 53 | CHUK | 0.68300412 |
| 54 | RIPK4 | 0.66512880 |
| 55 | MAPK12 | 0.66186179 |
| 56 | TYK2 | 0.66016626 |
| 57 | AURKA | 0.65832757 |
| 58 | MAPK7 | 0.63949811 |
| 59 | MAPK11 | 0.62999961 |
| 60 | CCNB1 | 0.59232613 |
| 61 | PTK6 | 0.58407712 |
| 62 | CDK12 | 0.57528487 |
| 63 | TGFBR2 | 0.54724514 |
| 64 | AKT3 | 0.52798758 |
| 65 | GSK3A | 0.52736512 |
| 66 | DDR2 | 0.52381658 |
| 67 | MAP3K12 | 0.52024294 |
| 68 | CDK6 | 0.51513870 |
| 69 | DAPK3 | 0.51444323 |
| 70 | PDK1 | 0.49907272 |
| 71 | EPHB1 | 0.47879964 |
| 72 | FGFR4 | 0.47539528 |
| 73 | PRPF4B | 0.43335677 |
| 74 | GRK7 | 0.43220594 |
| 75 | AKT2 | 0.43125241 |
| 76 | STK10 | 0.42517647 |
| 77 | MAP3K8 | 0.42367868 |
| 78 | SRPK1 | 0.41411952 |
| 79 | GRK6 | 0.39901269 |
| 80 | PRKG2 | 0.37830736 |
| 81 | VRK1 | 0.37277238 |
| 82 | CDK9 | 0.37198498 |
| 83 | JAK3 | 0.37020986 |
| 84 | MTOR | 0.35580013 |
| 85 | CAMK1D | 0.34754862 |
| 86 | FER | 0.33242015 |
| 87 | MELK | 0.33002820 |
| 88 | NME1 | 0.32241156 |
| 89 | MET | 0.29793082 |
| 90 | CSNK1G3 | 0.29503554 |
| 91 | PAK1 | 0.28641728 |
| 92 | CAMK4 | 0.27825183 |
| 93 | CSNK1A1L | 0.27667135 |
| 94 | RPS6KA1 | 0.27088311 |
| 95 | AURKB | 0.27043082 |
| 96 | TESK1 | 0.23577210 |
| 97 | SIK3 | 0.23533961 |
| 98 | CAMK2G | 0.23178086 |
| 99 | MAP3K5 | 0.22949620 |
| 100 | STK11 | 0.22389173 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 3.96777575 |
| 2 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.21951722 |
| 3 | Other glycan degradation_Homo sapiens_hsa00511 | 2.97347786 |
| 4 | Sulfur relay system_Homo sapiens_hsa04122 | 2.52113369 |
| 5 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.38397839 |
| 6 | Alcoholism_Homo sapiens_hsa05034 | 2.29924037 |
| 7 | Legionellosis_Homo sapiens_hsa05134 | 2.27276101 |
| 8 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.13795088 |
| 9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.08846999 |
| 10 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 2.07863964 |
| 11 | Lysosome_Homo sapiens_hsa04142 | 2.03928191 |
| 12 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.03511355 |
| 13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.00661629 |
| 14 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.95007372 |
| 15 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.85030803 |
| 16 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.78547035 |
| 17 | Leishmaniasis_Homo sapiens_hsa05140 | 1.76877201 |
| 18 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.75966009 |
| 19 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.72532623 |
| 20 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.63804413 |
| 21 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.60660421 |
| 22 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.60652410 |
| 23 | Pertussis_Homo sapiens_hsa05133 | 1.59798663 |
| 24 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.56502875 |
| 25 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.54993916 |
| 26 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.51294197 |
| 27 | Galactose metabolism_Homo sapiens_hsa00052 | 1.49186699 |
| 28 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.48653345 |
| 29 | Bladder cancer_Homo sapiens_hsa05219 | 1.41237680 |
| 30 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.40022269 |
| 31 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.36876834 |
| 32 | Malaria_Homo sapiens_hsa05144 | 1.35912859 |
| 33 | Tuberculosis_Homo sapiens_hsa05152 | 1.35234776 |
| 34 | Influenza A_Homo sapiens_hsa05164 | 1.33039017 |
| 35 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.30076278 |
| 36 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.29272341 |
| 37 | Salmonella infection_Homo sapiens_hsa05132 | 1.26840794 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25789261 |
| 39 | Hepatitis C_Homo sapiens_hsa05160 | 1.22882550 |
| 40 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.22169361 |
| 41 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.05341915 |
| 42 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.99822093 |
| 43 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.97623208 |
| 44 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.95450933 |
| 45 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.93387897 |
| 46 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.90563810 |
| 47 | Carbon metabolism_Homo sapiens_hsa01200 | 0.88639593 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.87063119 |
| 49 | DNA replication_Homo sapiens_hsa03030 | 0.84019381 |
| 50 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83679810 |
| 51 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.81666986 |
| 52 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.81582190 |
| 53 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.80663131 |
| 54 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.78257382 |
| 55 | Mineral absorption_Homo sapiens_hsa04978 | 0.77155687 |
| 56 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.75741411 |
| 57 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.74105908 |
| 58 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.72420819 |
| 59 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.70963765 |
| 60 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.68612079 |
| 61 | Hepatitis B_Homo sapiens_hsa05161 | 0.68034740 |
| 62 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.67991852 |
| 63 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66508308 |
| 64 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.66098482 |
| 65 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.65339598 |
| 66 | Apoptosis_Homo sapiens_hsa04210 | 0.64910614 |
| 67 | Amoebiasis_Homo sapiens_hsa05146 | 0.61915178 |
| 68 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.61838854 |
| 69 | Phagosome_Homo sapiens_hsa04145 | 0.56457982 |
| 70 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.56075589 |
| 71 | Prion diseases_Homo sapiens_hsa05020 | 0.55308644 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.55195385 |
| 73 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.54194839 |
| 74 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.52261177 |
| 75 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.49563305 |
| 76 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.48329857 |
| 77 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.46266119 |
| 78 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.45479309 |
| 79 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.43288345 |
| 80 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.42455492 |
| 81 | Asthma_Homo sapiens_hsa05310 | 0.41534479 |
| 82 | Shigellosis_Homo sapiens_hsa05131 | 0.40999879 |
| 83 | Histidine metabolism_Homo sapiens_hsa00340 | 0.39980083 |
| 84 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.39915983 |
| 85 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.38201056 |
| 86 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38179552 |
| 87 | Bile secretion_Homo sapiens_hsa04976 | 0.37423935 |
| 88 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.37240045 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.36925156 |
| 90 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.36690688 |
| 91 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.36584879 |
| 92 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.36461088 |
| 93 | Proteasome_Homo sapiens_hsa03050 | 0.36382252 |
| 94 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.36054797 |
| 95 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.35968516 |
| 96 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.35654334 |
| 97 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.34184449 |
| 98 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.33548126 |
| 99 | Allograft rejection_Homo sapiens_hsa05330 | 0.32272824 |
| 100 | Thyroid cancer_Homo sapiens_hsa05216 | 0.32254440 |

