Rank | Gene Set | Z-score |
---|---|---|
1 | intermediate filament organization (GO:0045109) | 9.10134706 |
2 | negative regulation of stress fiber assembly (GO:0051497) | 8.42549689 |
3 | negative regulation of actin filament bundle assembly (GO:0032232) | 6.65841823 |
4 | positive regulation of lamellipodium assembly (GO:0010592) | 5.88517250 |
5 | regulation of female receptivity (GO:0045924) | 5.53280647 |
6 | intermediate filament cytoskeleton organization (GO:0045104) | 5.21439579 |
7 | hair follicle morphogenesis (GO:0031069) | 5.20025658 |
8 | positive regulation of lamellipodium organization (GO:1902745) | 5.16772373 |
9 | intermediate filament-based process (GO:0045103) | 5.11209009 |
10 | regulation of mesoderm development (GO:2000380) | 5.01004586 |
11 | rRNA catabolic process (GO:0016075) | 4.96267480 |
12 | female mating behavior (GO:0060180) | 4.66550909 |
13 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.46264675 |
14 | somite development (GO:0061053) | 4.44056504 |
15 | fatty acid elongation (GO:0030497) | 4.30431644 |
16 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 4.28082061 |
17 | keratinization (GO:0031424) | 4.17706145 |
18 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 4.12642017 |
19 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 4.04910471 |
20 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.94678705 |
21 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.86958955 |
22 | desmosome organization (GO:0002934) | 3.75598749 |
23 | membrane repolarization during action potential (GO:0086011) | 3.74856940 |
24 | negative regulation by host of viral transcription (GO:0043922) | 3.72749285 |
25 | positive regulation of glomerulus development (GO:0090193) | 3.72210897 |
26 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.61564178 |
27 | lateral sprouting from an epithelium (GO:0060601) | 3.61270609 |
28 | regulation of memory T cell differentiation (GO:0043380) | 3.58396910 |
29 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.54816707 |
30 | protein polyglutamylation (GO:0018095) | 3.54348765 |
31 | DNA deamination (GO:0045006) | 3.50182830 |
32 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 3.42568881 |
33 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 3.39614366 |
34 | regulation of heart rate by cardiac conduction (GO:0086091) | 3.30960680 |
35 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.29412718 |
36 | aggressive behavior (GO:0002118) | 3.28221785 |
37 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.24998422 |
38 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.23553920 |
39 | phosphatidylethanolamine metabolic process (GO:0046337) | 3.21633771 |
40 | positive regulation of organelle assembly (GO:1902117) | 3.21559470 |
41 | rhodopsin mediated signaling pathway (GO:0016056) | 3.20739680 |
42 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 3.18071277 |
43 | ADP metabolic process (GO:0046031) | 3.14788132 |
44 | cardiac muscle cell action potential (GO:0086001) | 3.11089359 |
45 | regulation of glomerulus development (GO:0090192) | 3.10427614 |
46 | cellular response to interferon-beta (GO:0035458) | 3.09905162 |
47 | regulation of natural killer cell differentiation (GO:0032823) | 3.09897119 |
48 | positive thymic T cell selection (GO:0045059) | 3.08294867 |
49 | regulation of defense response to virus by host (GO:0050691) | 3.07665326 |
50 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.06616322 |
51 | regulation of triglyceride catabolic process (GO:0010896) | 3.01564864 |
52 | negative regulation of monooxygenase activity (GO:0032769) | 3.01536537 |
53 | response to interferon-beta (GO:0035456) | 2.92976972 |
54 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.92394527 |
55 | positive regulation of defense response to virus by host (GO:0002230) | 2.91984251 |
56 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.86520311 |
57 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.86489217 |
58 | multicellular organismal reproductive behavior (GO:0033057) | 2.85208619 |
59 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.84555181 |
60 | immunoglobulin mediated immune response (GO:0016064) | 2.84440406 |
61 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.78458506 |
62 | positive regulation of antigen processing and presentation (GO:0002579) | 2.72426435 |
63 | regulation of lamellipodium assembly (GO:0010591) | 2.72067108 |
64 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.71415847 |
65 | organ formation (GO:0048645) | 2.70868573 |
66 | interferon-gamma secretion (GO:0072643) | 2.68744151 |
67 | NAD biosynthetic process (GO:0009435) | 2.67848585 |
68 | killing of cells of other organism (GO:0031640) | 2.64514047 |
69 | disruption of cells of other organism (GO:0044364) | 2.64514047 |
70 | epithelial cilium movement (GO:0003351) | 2.64348563 |
71 | retinol metabolic process (GO:0042572) | 2.62828865 |
72 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.61275180 |
73 | multicellular organismal signaling (GO:0035637) | 2.61249636 |
74 | ncRNA catabolic process (GO:0034661) | 2.60459477 |
75 | peptide cross-linking (GO:0018149) | 2.60149900 |
76 | magnesium ion transport (GO:0015693) | 2.59508541 |
77 | regulation of antigen processing and presentation (GO:0002577) | 2.58195886 |
78 | defense response to fungus (GO:0050832) | 2.57686044 |
79 | cardiac conduction (GO:0061337) | 2.57127405 |
80 | regulation of sequestering of triglyceride (GO:0010889) | 2.56145607 |
81 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.52205271 |
82 | lung-associated mesenchyme development (GO:0060484) | 2.51831106 |
83 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.51518197 |
84 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.51369811 |
85 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.50604310 |
86 | molting cycle process (GO:0022404) | 2.46485557 |
87 | hair cycle process (GO:0022405) | 2.46485557 |
88 | regulation of lamellipodium organization (GO:1902743) | 2.45240390 |
89 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.45143758 |
90 | epidermis development (GO:0008544) | 2.44134538 |
91 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.43603632 |
92 | sulfation (GO:0051923) | 2.42841316 |
93 | potassium ion export (GO:0071435) | 2.42079730 |
94 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.41757310 |
95 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.41618661 |
96 | transmission of nerve impulse (GO:0019226) | 2.41454132 |
97 | negative thymic T cell selection (GO:0045060) | 2.40808982 |
98 | axoneme assembly (GO:0035082) | 2.40160735 |
99 | molting cycle (GO:0042303) | 18.0429306 |
100 | hair cycle (GO:0042633) | 18.0429306 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.21004232 |
2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.13374917 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.67495404 |
4 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.82770435 |
5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.72591508 |
6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.64429122 |
7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.58114168 |
8 | ERG_20517297_ChIP-Seq_VCAP_Human | 2.35805392 |
9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.23458723 |
10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.16542468 |
11 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.95647045 |
12 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.93000060 |
13 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.89165134 |
14 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.79106658 |
15 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.71321929 |
16 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.68015669 |
17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.65325412 |
18 | RXR_22108803_ChIP-Seq_LS180_Human | 1.65304335 |
19 | AR_20517297_ChIP-Seq_VCAP_Human | 1.64889324 |
20 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.63647113 |
21 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63248036 |
22 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.57866974 |
23 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.55226194 |
24 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.52832311 |
25 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.49988222 |
26 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.47520571 |
27 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.47457735 |
28 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.47457735 |
29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.46944341 |
30 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.46809851 |
31 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.45451886 |
32 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.45429470 |
33 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.44972797 |
34 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.44972797 |
35 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.44790095 |
36 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.43633067 |
37 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.43408283 |
38 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.42778875 |
39 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.41432011 |
40 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.38498394 |
41 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.37891029 |
42 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.36820166 |
43 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.36083360 |
44 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.33728986 |
45 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.33005966 |
46 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32689573 |
47 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.31592577 |
48 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.29985307 |
49 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.28616322 |
50 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.27144902 |
51 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26792644 |
52 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.26286630 |
53 | NCOR_22424771_ChIP-Seq_293T_Human | 1.25958775 |
54 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.23702011 |
55 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.22472191 |
56 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.20808560 |
57 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.20613357 |
58 | P300_27268052_Chip-Seq_Bcells_Human | 1.18621904 |
59 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.16606086 |
60 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.15570171 |
61 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.14656690 |
62 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.13405173 |
63 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.11027741 |
64 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.10669592 |
65 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.09489693 |
66 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.09449860 |
67 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.09191479 |
68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.07965697 |
69 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.07717899 |
70 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.07524725 |
71 | FUS_26573619_Chip-Seq_HEK293_Human | 1.05938556 |
72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05422644 |
73 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.04821340 |
74 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.04789465 |
75 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04583689 |
76 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04002879 |
77 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.03878402 |
78 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.03723410 |
79 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.03241031 |
80 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.03125951 |
81 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.02024042 |
82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.01284121 |
83 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.00663121 |
84 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00339005 |
85 | AR_25329375_ChIP-Seq_VCAP_Human | 1.00238034 |
86 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99757604 |
87 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99757604 |
88 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.98536141 |
89 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.98083895 |
90 | * TP53_22573176_ChIP-Seq_HFKS_Human | 0.97458080 |
91 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.97068967 |
92 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.96125713 |
93 | GATA3_26560356_Chip-Seq_TH2_Human | 0.95994787 |
94 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.95955567 |
95 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.94678917 |
96 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.94502888 |
97 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.94497189 |
98 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.93653224 |
99 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.93477560 |
100 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.93080669 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000647_abnormal_sebaceous_gland | 5.14394244 |
2 | MP0002098_abnormal_vibrissa_morphology | 4.52169376 |
3 | MP0000383_abnormal_hair_follicle | 4.29383692 |
4 | MP0005646_abnormal_pituitary_gland | 4.09591511 |
5 | MP0004885_abnormal_endolymph | 3.77681605 |
6 | MP0005377_hearing/vestibular/ear_phenot | 3.63725264 |
7 | MP0003878_abnormal_ear_physiology | 3.63725264 |
8 | MP0000579_abnormal_nail_morphology | 3.58436396 |
9 | MP0010678_abnormal_skin_adnexa | 3.56881002 |
10 | MP0009780_abnormal_chondrocyte_physiolo | 2.80249275 |
11 | MP0005275_abnormal_skin_tensile | 2.79828999 |
12 | MP0009379_abnormal_foot_pigmentation | 2.75503504 |
13 | MP0000377_abnormal_hair_follicle | 2.68531675 |
14 | MP0003283_abnormal_digestive_organ | 2.59358804 |
15 | MP0004381_abnormal_hair_follicle | 2.53588901 |
16 | MP0000467_abnormal_esophagus_morphology | 2.46317745 |
17 | MP0003646_muscle_fatigue | 2.46087109 |
18 | MP0002138_abnormal_hepatobiliary_system | 2.35027763 |
19 | MP0000537_abnormal_urethra_morphology | 2.30542517 |
20 | MP0002876_abnormal_thyroid_physiology | 2.28713869 |
21 | MP0009053_abnormal_anal_canal | 2.21490023 |
22 | MP0004130_abnormal_muscle_cell | 2.15650830 |
23 | MP0003011_delayed_dark_adaptation | 2.02577367 |
24 | MP0002102_abnormal_ear_morphology | 2.02514724 |
25 | MP0002796_impaired_skin_barrier | 2.02420521 |
26 | MP0005075_abnormal_melanosome_morpholog | 1.99313086 |
27 | MP0000427_abnormal_hair_cycle | 1.95643732 |
28 | MP0002282_abnormal_trachea_morphology | 1.90601573 |
29 | MP0010234_abnormal_vibrissa_follicle | 1.83945109 |
30 | MP0001485_abnormal_pinna_reflex | 1.78514778 |
31 | MP0002254_reproductive_system_inflammat | 1.75787598 |
32 | MP0002837_dystrophic_cardiac_calcinosis | 1.71969251 |
33 | MP0002095_abnormal_skin_pigmentation | 1.63668813 |
34 | MP0001661_extended_life_span | 1.54159303 |
35 | MP0000367_abnormal_coat/_hair | 1.47039973 |
36 | MP0005174_abnormal_tail_pigmentation | 1.43890566 |
37 | MP0010771_integument_phenotype | 1.40536364 |
38 | MP0004145_abnormal_muscle_electrophysio | 1.35994858 |
39 | MP0001968_abnormal_touch/_nociception | 1.34141102 |
40 | MP0001243_abnormal_dermal_layer | 1.27706508 |
41 | MP0005670_abnormal_white_adipose | 1.26194844 |
42 | MP0004947_skin_inflammation | 1.24505597 |
43 | MP0000015_abnormal_ear_pigmentation | 1.21575303 |
44 | MP0001216_abnormal_epidermal_layer | 1.19706535 |
45 | MP0003137_abnormal_impulse_conducting | 1.18754845 |
46 | MP0003806_abnormal_nucleotide_metabolis | 1.18395495 |
47 | MP0002160_abnormal_reproductive_system | 1.15989688 |
48 | MP0004782_abnormal_surfactant_physiolog | 1.14518340 |
49 | MP0000569_abnormal_digit_pigmentation | 1.08107234 |
50 | MP0005464_abnormal_platelet_physiology | 1.07564341 |
51 | MP0003119_abnormal_digestive_system | 1.03629958 |
52 | MP0005647_abnormal_sex_gland | 1.01939969 |
53 | MP0005501_abnormal_skin_physiology | 0.98354560 |
54 | MP0002060_abnormal_skin_morphology | 0.97189554 |
55 | MP0000681_abnormal_thyroid_gland | 0.96898426 |
56 | MP0003879_abnormal_hair_cell | 0.96733716 |
57 | MP0005389_reproductive_system_phenotype | 0.96144499 |
58 | MP0000372_irregular_coat_pigmentation | 0.94441871 |
59 | MP0003938_abnormal_ear_development | 0.92718197 |
60 | MP0003453_abnormal_keratinocyte_physiol | 0.84042257 |
61 | MP0001919_abnormal_reproductive_system | 0.83587164 |
62 | MP0005000_abnormal_immune_tolerance | 0.79474113 |
63 | MP0002736_abnormal_nociception_after | 0.78634922 |
64 | MP0002139_abnormal_hepatobiliary_system | 0.78584644 |
65 | MP0005220_abnormal_exocrine_pancreas | 0.77667701 |
66 | MP0008775_abnormal_heart_ventricle | 0.77574257 |
67 | MP0004185_abnormal_adipocyte_glucose | 0.77381503 |
68 | MP0005360_urolithiasis | 0.75368938 |
69 | MP0009931_abnormal_skin_appearance | 0.74724369 |
70 | MP0003724_increased_susceptibility_to | 0.73378739 |
71 | MP0000613_abnormal_salivary_gland | 0.71475392 |
72 | MP0000685_abnormal_immune_system | 0.70004971 |
73 | MP0005551_abnormal_eye_electrophysiolog | 0.69801023 |
74 | MP0003638_abnormal_response/metabolism_ | 0.67576678 |
75 | MP0001800_abnormal_humoral_immune | 0.67520826 |
76 | MP0008004_abnormal_stomach_pH | 0.65880461 |
77 | MP0002148_abnormal_hypersensitivity_rea | 0.65583447 |
78 | MP0003436_decreased_susceptibility_to | 0.63498968 |
79 | MP0005671_abnormal_response_to | 0.62135694 |
80 | MP0001835_abnormal_antigen_presentation | 0.60416709 |
81 | MP0006082_CNS_inflammation | 0.59546999 |
82 | MP0000631_abnormal_neuroendocrine_gland | 0.57583598 |
83 | MP0000230_abnormal_systemic_arterial | 0.57556222 |
84 | MP0001963_abnormal_hearing_physiology | 0.56184579 |
85 | MP0004134_abnormal_chest_morphology | 0.55301434 |
86 | MP0005503_abnormal_tendon_morphology | 0.55241155 |
87 | MP0001533_abnormal_skeleton_physiology | 0.54989817 |
88 | MP0000026_abnormal_inner_ear | 0.53949363 |
89 | MP0006072_abnormal_retinal_apoptosis | 0.52811360 |
90 | MP0008875_abnormal_xenobiotic_pharmacok | 0.50843256 |
91 | MP0003191_abnormal_cellular_cholesterol | 0.49985865 |
92 | MP0005410_abnormal_fertilization | 0.49240741 |
93 | MP0004215_abnormal_myocardial_fiber | 0.49132746 |
94 | MP0002733_abnormal_thermal_nociception | 0.48393817 |
95 | MP0001486_abnormal_startle_reflex | 0.47962138 |
96 | MP0008058_abnormal_DNA_repair | 0.47852248 |
97 | MP0002723_abnormal_immune_serum | 0.46240360 |
98 | MP0009765_abnormal_xenobiotic_induced | 0.44651964 |
99 | MP0003195_calcinosis | 0.44475640 |
100 | MP0001663_abnormal_digestive_system | 0.43275484 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pili torti (HP:0003777) | 8.06827281 |
2 | Onycholysis (HP:0001806) | 7.20070804 |
3 | Brittle hair (HP:0002299) | 6.72506287 |
4 | Woolly hair (HP:0002224) | 6.48673548 |
5 | Abnormality of hair growth rate (HP:0011363) | 5.77089020 |
6 | Slow-growing hair (HP:0002217) | 5.77089020 |
7 | Hypotrichosis (HP:0001006) | 5.25532357 |
8 | Abnormal hair laboratory examination (HP:0003328) | 4.93203701 |
9 | Absent eyelashes (HP:0000561) | 4.43204383 |
10 | Absent eyebrow (HP:0002223) | 4.27125501 |
11 | Congenital, generalized hypertrichosis (HP:0004540) | 4.15817673 |
12 | Morphological abnormality of the middle ear (HP:0008609) | 3.82943531 |
13 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.70813011 |
14 | Absent hair (HP:0002298) | 3.63238858 |
15 | Dry hair (HP:0011359) | 3.50578584 |
16 | Erythroderma (HP:0001019) | 3.45719210 |
17 | Bilateral microphthalmos (HP:0007633) | 3.45089320 |
18 | Abnormality of the nasal septum (HP:0000419) | 3.18042422 |
19 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 3.02904895 |
20 | Erythema (HP:0010783) | 3.00631960 |
21 | Abnormality of the axillary hair (HP:0100134) | 2.94840813 |
22 | Abnormality of secondary sexual hair (HP:0009888) | 2.94840813 |
23 | Short hallux (HP:0010109) | 2.93065485 |
24 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.83372679 |
25 | Abnormality of nail color (HP:0100643) | 2.80963047 |
26 | Palmoplantar hyperkeratosis (HP:0000972) | 2.79377986 |
27 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.78171594 |
28 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.72400068 |
29 | Ventricular fibrillation (HP:0001663) | 2.70817053 |
30 | Thyroid-stimulating hormone excess (HP:0002925) | 2.70383216 |
31 | Increased IgE level (HP:0003212) | 2.70103121 |
32 | Hyperthyroidism (HP:0000836) | 2.65947704 |
33 | Asplenia (HP:0001746) | 2.65232518 |
34 | Methylmalonic acidemia (HP:0002912) | 2.64008995 |
35 | Synostosis involving the elbow (HP:0003938) | 2.61203428 |
36 | Humeroradial synostosis (HP:0003041) | 2.61203428 |
37 | Nail dystrophy (HP:0008404) | 2.61059337 |
38 | Fine hair (HP:0002213) | 2.58871929 |
39 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.58772042 |
40 | Palmar hyperkeratosis (HP:0010765) | 2.56630534 |
41 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.54404409 |
42 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.53472822 |
43 | Thick nail (HP:0001805) | 2.51105812 |
44 | Furrowed tongue (HP:0000221) | 2.48088233 |
45 | Stomach cancer (HP:0012126) | 2.46281842 |
46 | Alopecia of scalp (HP:0002293) | 2.39141435 |
47 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.33586098 |
48 | Hematochezia (HP:0002573) | 2.27470672 |
49 | Conjunctival hamartoma (HP:0100780) | 2.26191712 |
50 | Abnormality of the costochondral junction (HP:0000919) | 2.26019525 |
51 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.25664291 |
52 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.25590581 |
53 | Hyperglycinemia (HP:0002154) | 2.22264634 |
54 | Long nose (HP:0003189) | 2.21505817 |
55 | Absent phalangeal crease (HP:0006109) | 2.20661286 |
56 | Pancreatic cysts (HP:0001737) | 2.14833600 |
57 | Plantar hyperkeratosis (HP:0007556) | 2.14074762 |
58 | Congenital stationary night blindness (HP:0007642) | 2.12186232 |
59 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.08443874 |
60 | Follicular hyperkeratosis (HP:0007502) | 2.06777037 |
61 | Large for gestational age (HP:0001520) | 2.06534765 |
62 | Abolished electroretinogram (ERG) (HP:0000550) | 2.05782908 |
63 | Syncope (HP:0001279) | 2.05586293 |
64 | Decreased circulating renin level (HP:0003351) | 2.04108406 |
65 | Spontaneous abortion (HP:0005268) | 2.02367907 |
66 | Sparse eyelashes (HP:0000653) | 1.99978213 |
67 | Right ventricular cardiomyopathy (HP:0011663) | 1.97636933 |
68 | Fragile nails (HP:0001808) | 1.93786152 |
69 | Methylmalonic aciduria (HP:0012120) | 1.93196967 |
70 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.90955779 |
71 | Short 1st metacarpal (HP:0010034) | 1.90955779 |
72 | Chorioretinal atrophy (HP:0000533) | 1.88320702 |
73 | Nephronophthisis (HP:0000090) | 1.86710565 |
74 | Pendular nystagmus (HP:0012043) | 1.86620357 |
75 | Absent/shortened dynein arms (HP:0200106) | 1.85990308 |
76 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.85990308 |
77 | Ketosis (HP:0001946) | 1.85901893 |
78 | Abnormality of the renal cortex (HP:0011035) | 1.84663930 |
79 | Abnormality of the columella (HP:0009929) | 1.84616404 |
80 | Cutaneous finger syndactyly (HP:0010554) | 1.84218342 |
81 | Abnormality of the prostate (HP:0008775) | 1.81315543 |
82 | Corneal erosion (HP:0200020) | 1.78677221 |
83 | Abnormality of the pupil (HP:0000615) | 1.75327355 |
84 | Abnormal finger flexion creases (HP:0006143) | 1.72993901 |
85 | Short femoral neck (HP:0100864) | 1.71895129 |
86 | Small epiphyses (HP:0010585) | 1.71113538 |
87 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.70632542 |
88 | Lipid accumulation in hepatocytes (HP:0006561) | 1.69861284 |
89 | Renal cortical cysts (HP:0000803) | 1.69602971 |
90 | Short phalanx of the thumb (HP:0009660) | 1.69071826 |
91 | Abnormality of the 1st metacarpal (HP:0010009) | 1.68830463 |
92 | Keratoconus (HP:0000563) | 1.68695526 |
93 | Increased corneal curvature (HP:0100692) | 1.68695526 |
94 | Attenuation of retinal blood vessels (HP:0007843) | 1.68468609 |
95 | Increased hepatocellular lipid droplets (HP:0006565) | 1.65759263 |
96 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.65595560 |
97 | Hyperalaninemia (HP:0003348) | 1.65279058 |
98 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.65279058 |
99 | Abnormality of alanine metabolism (HP:0010916) | 1.65279058 |
100 | Keratoconjunctivitis (HP:0001096) | 1.64033325 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 3.66018500 |
2 | ZAK | 3.28903240 |
3 | ITK | 3.25099619 |
4 | STK16 | 3.19241428 |
5 | TLK1 | 3.11590958 |
6 | GRK1 | 3.10994631 |
7 | ADRBK2 | 3.06028318 |
8 | EIF2AK3 | 2.80700856 |
9 | KDR | 2.72036196 |
10 | TEC | 2.71753112 |
11 | KIT | 2.43714171 |
12 | IKBKE | 2.28873853 |
13 | GRK7 | 2.20119425 |
14 | CAMKK2 | 1.82947743 |
15 | PDK2 | 1.80842909 |
16 | RIPK4 | 1.73223742 |
17 | MAPKAPK3 | 1.69044112 |
18 | PHKG2 | 1.67261498 |
19 | PHKG1 | 1.67261498 |
20 | BTK | 1.62848942 |
21 | NUAK1 | 1.58844715 |
22 | TAOK3 | 1.54985044 |
23 | TESK2 | 1.53401909 |
24 | BCKDK | 1.31854350 |
25 | MST4 | 1.30430004 |
26 | CAMKK1 | 1.29928851 |
27 | RPS6KA5 | 1.28558367 |
28 | PRKCQ | 1.25178769 |
29 | SYK | 1.24486489 |
30 | ADRBK1 | 1.20030122 |
31 | CSF1R | 1.19166421 |
32 | ABL1 | 1.18057771 |
33 | FGFR2 | 1.17971033 |
34 | MAP4K2 | 1.12235031 |
35 | IKBKB | 1.12077385 |
36 | TXK | 1.10174651 |
37 | VRK1 | 1.06998911 |
38 | MAP2K6 | 1.05578780 |
39 | RPS6KA6 | 1.05110034 |
40 | MAP4K1 | 1.03782079 |
41 | MAP3K9 | 1.02536402 |
42 | OXSR1 | 0.93596856 |
43 | LYN | 0.93136686 |
44 | PASK | 0.91232797 |
45 | HCK | 0.90296280 |
46 | PLK2 | 0.87180369 |
47 | FES | 0.84935102 |
48 | INSRR | 0.84791888 |
49 | GRK5 | 0.80181381 |
50 | PLK4 | 0.80048593 |
51 | LCK | 0.77008696 |
52 | MAPK7 | 0.76394918 |
53 | BMPR2 | 0.75696581 |
54 | MAPK3 | 0.75690559 |
55 | PIM1 | 0.74926810 |
56 | TIE1 | 0.72337023 |
57 | MAP2K2 | 0.71532910 |
58 | DAPK2 | 0.70768292 |
59 | BRSK2 | 0.70576638 |
60 | STK39 | 0.69821375 |
61 | RPS6KC1 | 0.68691164 |
62 | RPS6KL1 | 0.68691164 |
63 | PDK1 | 0.68652537 |
64 | FLT3 | 0.67799069 |
65 | MAPK15 | 0.66755016 |
66 | NME1 | 0.66413662 |
67 | PINK1 | 0.65851870 |
68 | MAPK13 | 0.64827056 |
69 | CDK3 | 0.63149795 |
70 | WNK4 | 0.62523890 |
71 | RPS6KA2 | 0.62327296 |
72 | TGFBR1 | 0.61110514 |
73 | TBK1 | 0.60169323 |
74 | PIK3CA | 0.59185817 |
75 | STK10 | 0.58243763 |
76 | PIK3CG | 0.56893078 |
77 | MAPKAPK5 | 0.52886783 |
78 | GRK6 | 0.52262181 |
79 | VRK2 | 0.50055783 |
80 | TRPM7 | 0.48813021 |
81 | CSNK1A1 | 0.47539650 |
82 | DAPK1 | 0.47125982 |
83 | PIM2 | 0.46220838 |
84 | FER | 0.46187280 |
85 | BMPR1B | 0.45236974 |
86 | MAP3K5 | 0.44397092 |
87 | IGF1R | 0.41812488 |
88 | STK11 | 0.40299520 |
89 | MKNK1 | 0.39387659 |
90 | CSNK1G1 | 0.39229897 |
91 | WEE1 | 0.38158940 |
92 | CSNK2A1 | 0.37162489 |
93 | OBSCN | 0.36753264 |
94 | PRKCA | 0.36217284 |
95 | GSK3A | 0.35385043 |
96 | CSNK1G3 | 0.35096754 |
97 | RPS6KA1 | 0.33308329 |
98 | PRKACA | 0.32458532 |
99 | MOS | 0.31643592 |
100 | MAPK1 | 0.30947470 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Asthma_Homo sapiens_hsa05310 | 3.87222173 |
2 | Allograft rejection_Homo sapiens_hsa05330 | 3.39257658 |
3 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.27906231 |
4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.23718418 |
5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.12903452 |
6 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.98624773 |
7 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.66632660 |
8 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.35928731 |
9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.28796666 |
10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.28706919 |
11 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.27413166 |
12 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 2.27248436 |
13 | Phototransduction_Homo sapiens_hsa04744 | 2.25408611 |
14 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.21695512 |
15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.87570947 |
16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.80236406 |
17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.67370128 |
18 | Other glycan degradation_Homo sapiens_hsa00511 | 1.66693995 |
19 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.64619738 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.61675256 |
21 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.58043577 |
22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.53665939 |
23 | Retinol metabolism_Homo sapiens_hsa00830 | 1.48202003 |
24 | Homologous recombination_Homo sapiens_hsa03440 | 1.45422710 |
25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.45195059 |
26 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.43251494 |
27 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.41239515 |
28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.36928557 |
29 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.34745999 |
30 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.32069318 |
31 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.31082091 |
32 | RNA degradation_Homo sapiens_hsa03018 | 1.30125551 |
33 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.28210836 |
34 | Leishmaniasis_Homo sapiens_hsa05140 | 1.26777994 |
35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.23572109 |
36 | Salivary secretion_Homo sapiens_hsa04970 | 1.20345051 |
37 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.19451279 |
38 | Histidine metabolism_Homo sapiens_hsa00340 | 1.18973381 |
39 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.17296570 |
40 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.11114245 |
41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.04390375 |
42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.01885772 |
43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.00992226 |
44 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.96621618 |
45 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.96438601 |
46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.96206661 |
47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92010493 |
48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85668185 |
49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.85540861 |
50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.83003966 |
51 | Taste transduction_Homo sapiens_hsa04742 | 0.82602862 |
52 | Circadian entrainment_Homo sapiens_hsa04713 | 0.80291398 |
53 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.80170156 |
54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.73340218 |
55 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.72953432 |
56 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.70076025 |
57 | Peroxisome_Homo sapiens_hsa04146 | 0.68591688 |
58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68398539 |
59 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.66459407 |
60 | Morphine addiction_Homo sapiens_hsa05032 | 0.65890122 |
61 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.65824806 |
62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.64949720 |
63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61455829 |
64 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60858615 |
65 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.59818736 |
66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.57204765 |
67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.57171190 |
68 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.56002602 |
69 | Nicotine addiction_Homo sapiens_hsa05033 | 0.54898752 |
70 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.54502581 |
71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53197628 |
72 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51130751 |
73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48816779 |
74 | Pertussis_Homo sapiens_hsa05133 | 0.43210572 |
75 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.43115710 |
76 | ABC transporters_Homo sapiens_hsa02010 | 0.41995887 |
77 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.41758649 |
78 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.40573402 |
79 | Proteasome_Homo sapiens_hsa03050 | 0.38540976 |
80 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.36308759 |
81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35115391 |
82 | Malaria_Homo sapiens_hsa05144 | 0.34770474 |
83 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33522862 |
84 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.32601557 |
85 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.31096688 |
86 | Tuberculosis_Homo sapiens_hsa05152 | 0.30482239 |
87 | Renin secretion_Homo sapiens_hsa04924 | 0.30291985 |
88 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.30061150 |
89 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.26547802 |
90 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.26351295 |
91 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.26307613 |
92 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.25727469 |
93 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.25690325 |
94 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.24131933 |
95 | Purine metabolism_Homo sapiens_hsa00230 | 0.23687369 |
96 | Shigellosis_Homo sapiens_hsa05131 | 0.22702168 |
97 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.22251081 |
98 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.21981221 |
99 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.21903007 |
100 | Mineral absorption_Homo sapiens_hsa04978 | 0.21524174 |