Rank | Gene Set | Z-score |
---|---|---|
1 | virion attachment to host cell (GO:0019062) | 9.73375160 |
2 | adhesion of symbiont to host cell (GO:0044650) | 9.73375160 |
3 | peptide cross-linking (GO:0018149) | 8.69028591 |
4 | hair follicle morphogenesis (GO:0031069) | 8.43406351 |
5 | citrulline biosynthetic process (GO:0019240) | 8.22040090 |
6 | adhesion of symbiont to host (GO:0044406) | 8.15619364 |
7 | intermediate filament cytoskeleton organization (GO:0045104) | 6.79084119 |
8 | cell wall macromolecule catabolic process (GO:0016998) | 6.64540872 |
9 | cell wall macromolecule metabolic process (GO:0044036) | 6.64540872 |
10 | intermediate filament-based process (GO:0045103) | 6.56839742 |
11 | epidermis development (GO:0008544) | 6.47281620 |
12 | establishment of skin barrier (GO:0061436) | 6.34718421 |
13 | keratinocyte differentiation (GO:0030216) | 6.06729599 |
14 | hair cycle process (GO:0022405) | 5.72996596 |
15 | molting cycle process (GO:0022404) | 5.72996596 |
16 | regulation of water loss via skin (GO:0033561) | 5.62527120 |
17 | citrulline metabolic process (GO:0000052) | 5.43724234 |
18 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.87006421 |
19 | epidermal cell differentiation (GO:0009913) | 4.73816258 |
20 | hemidesmosome assembly (GO:0031581) | 4.65835731 |
21 | peptidyl-arginine modification (GO:0018195) | 4.52463358 |
22 | skin morphogenesis (GO:0043589) | 4.11358297 |
23 | hair cycle (GO:0042633) | 32.7194516 |
24 | molting cycle (GO:0042303) | 32.7194516 |
25 | keratinocyte development (GO:0003334) | 3.84893166 |
26 | tooth mineralization (GO:0034505) | 3.84428829 |
27 | multicellular organismal water homeostasis (GO:0050891) | 3.75399212 |
28 | hair follicle development (GO:0001942) | 3.74699873 |
29 | regulation of keratinocyte differentiation (GO:0045616) | 3.71339436 |
30 | bone trabecula formation (GO:0060346) | 3.53827287 |
31 | positive regulation of hair follicle development (GO:0051798) | 3.36548567 |
32 | positive regulation of hair cycle (GO:0042635) | 3.36548567 |
33 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.36412923 |
34 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.31281595 |
35 | gap junction assembly (GO:0016264) | 3.20598439 |
36 | positive regulation of meiotic cell cycle (GO:0051446) | 3.17684178 |
37 | negative regulation of establishment of protein localization to plasma membrane (GO:0090005) | 3.12228662 |
38 | regulation of hair follicle development (GO:0051797) | 3.12123526 |
39 | epithelium development (GO:0060429) | 3.08379432 |
40 | water homeostasis (GO:0030104) | 3.07336663 |
41 | regulation of hair cycle (GO:0042634) | 2.99641676 |
42 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.97594948 |
43 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.89802181 |
44 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 2.78286881 |
45 | regulation of epidermal cell differentiation (GO:0045604) | 2.77849996 |
46 | cranial suture morphogenesis (GO:0060363) | 2.76871154 |
47 | positive regulation of epidermis development (GO:0045684) | 2.65887761 |
48 | wound healing, spreading of epidermal cells (GO:0035313) | 2.59731916 |
49 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.59684105 |
50 | regulation of epidermis development (GO:0045682) | 2.58389583 |
51 | ectoderm development (GO:0007398) | 2.54925928 |
52 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 2.49894564 |
53 | fatty acid elongation (GO:0030497) | 2.49114165 |
54 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.46883285 |
55 | atrioventricular valve morphogenesis (GO:0003181) | 2.25538620 |
56 | phosphatidylserine metabolic process (GO:0006658) | 2.24702355 |
57 | negative regulation of epidermis development (GO:0045683) | 2.24321447 |
58 | keratinocyte proliferation (GO:0043616) | 2.23955857 |
59 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.22603463 |
60 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.20638997 |
61 | regulation of ruffle assembly (GO:1900027) | 2.19183966 |
62 | positive regulation of epidermal cell differentiation (GO:0045606) | 2.14437135 |
63 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 2.11713364 |
64 | skin development (GO:0043588) | 2.08274530 |
65 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.06242800 |
66 | negative regulation of cell fate specification (GO:0009996) | 2.04954116 |
67 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 2.02137505 |
68 | ephrin receptor signaling pathway (GO:0048013) | 2.00018010 |
69 | keratinization (GO:0031424) | 12.3517591 |
70 | intermediate filament organization (GO:0045109) | 12.0012200 |
71 | desmosome organization (GO:0002934) | 10.4421670 |
72 | craniofacial suture morphogenesis (GO:0097094) | 1.98543586 |
73 | non-canonical Wnt signaling pathway (GO:0035567) | 1.96378851 |
74 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 1.93967000 |
75 | negative regulation of epidermal cell differentiation (GO:0045605) | 1.92390155 |
76 | outflow tract septum morphogenesis (GO:0003148) | 1.90916804 |
77 | aging (GO:0007568) | 1.89897333 |
78 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 1.89621037 |
79 | regulation of keratinocyte proliferation (GO:0010837) | 1.88925506 |
80 | regulation of heart rate by cardiac conduction (GO:0086091) | 1.88426037 |
81 | epithelial cell-cell adhesion (GO:0090136) | 1.86508884 |
82 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 1.86489022 |
83 | cell communication involved in cardiac conduction (GO:0086065) | 1.86109722 |
84 | chondrocyte development (GO:0002063) | 1.85968529 |
85 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 1.80121398 |
86 | positive regulation of meiosis (GO:0045836) | 1.79770589 |
87 | wound healing, spreading of cells (GO:0044319) | 1.78785523 |
88 | establishment of planar polarity (GO:0001736) | 1.78722258 |
89 | establishment of tissue polarity (GO:0007164) | 1.78722258 |
90 | very long-chain fatty acid metabolic process (GO:0000038) | 1.76419998 |
91 | regulation of cardioblast differentiation (GO:0051890) | 1.76018560 |
92 | lateral sprouting from an epithelium (GO:0060601) | 1.76008205 |
93 | regulation of monocyte chemotaxis (GO:0090025) | 1.75380888 |
94 | cellular zinc ion homeostasis (GO:0006882) | 1.74638027 |
95 | myotube differentiation (GO:0014902) | 1.72724938 |
96 | lymph vessel development (GO:0001945) | 1.71042030 |
97 | eyelid development in camera-type eye (GO:0061029) | 1.69693073 |
98 | cell-substrate junction assembly (GO:0007044) | 1.68769067 |
99 | cardiac epithelial to mesenchymal transition (GO:0060317) | 1.68171155 |
100 | negative regulation of neurotransmitter secretion (GO:0046929) | 1.67419384 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.12549705 |
2 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 5.30893879 |
3 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 3.71900310 |
4 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.13540321 |
5 | CTCF_20526341_ChIP-Seq_ESCs_Human | 2.25894628 |
6 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 12.6029302 |
7 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.98300987 |
8 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 1.82587788 |
9 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.77888944 |
10 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.76764595 |
11 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.76299232 |
12 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.73474461 |
13 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.73264272 |
14 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.70161661 |
15 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 1.69142257 |
16 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 1.67574614 |
17 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.67310874 |
18 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.66645014 |
19 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.65204156 |
20 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.62434095 |
21 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.58225020 |
22 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.57339217 |
23 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.57339217 |
24 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.52119488 |
25 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.50580869 |
26 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.49332436 |
27 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.45373862 |
28 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.44812651 |
29 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.44550813 |
30 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.44450872 |
31 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.42285374 |
32 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.41765477 |
33 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.41359713 |
34 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.39539789 |
35 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.39297345 |
36 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.38181091 |
37 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.37927388 |
38 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.37757914 |
39 | MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse | 1.37330988 |
40 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.30767299 |
41 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.28617488 |
42 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.27086078 |
43 | CEBPB_22108803_ChIP-Seq_LS180_Human | 1.25557603 |
44 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.23941333 |
45 | ATF3_27146783_Chip-Seq_COLON_Human | 1.22801460 |
46 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.20399990 |
47 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.17850017 |
48 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.16817390 |
49 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.15333895 |
50 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.13943954 |
51 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.13383555 |
52 | P68_20966046_ChIP-Seq_HELA_Human | 1.12981982 |
53 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.12860745 |
54 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.12500829 |
55 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.10515684 |
56 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.07629075 |
57 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.05932434 |
58 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.03491794 |
59 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.03140700 |
60 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.02704971 |
61 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02043807 |
62 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.00914067 |
63 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.00567873 |
64 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.99338010 |
65 | RXR_22108803_ChIP-Seq_LS180_Human | 0.99318593 |
66 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.98553666 |
67 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98439124 |
68 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.98299939 |
69 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.98218741 |
70 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.97691672 |
71 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.97276252 |
72 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.96970143 |
73 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.95425590 |
74 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.95280926 |
75 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.94980668 |
76 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94688823 |
77 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.94135514 |
78 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.93834076 |
79 | * E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.93469242 |
80 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.92631667 |
81 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.92556139 |
82 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.92109620 |
83 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.90261744 |
84 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.90169817 |
85 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.90034128 |
86 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.89025579 |
87 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.88597628 |
88 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.88405431 |
89 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.86558368 |
90 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.86558368 |
91 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.84776578 |
92 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.83931922 |
93 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.82557848 |
94 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.81635909 |
95 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.81616653 |
96 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.80985011 |
97 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.79991456 |
98 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.78593404 |
99 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.76020107 |
100 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.75653611 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000579_abnormal_nail_morphology | 7.52825961 |
2 | MP0002098_abnormal_vibrissa_morphology | 7.05528586 |
3 | MP0000647_abnormal_sebaceous_gland | 6.20328179 |
4 | MP0002796_impaired_skin_barrier | 5.71385072 |
5 | MP0005275_abnormal_skin_tensile | 5.32439395 |
6 | MP0000383_abnormal_hair_follicle | 5.19419767 |
7 | MP0010234_abnormal_vibrissa_follicle | 4.85514691 |
8 | MP0010678_abnormal_skin_adnexa | 4.55164713 |
9 | MP0000377_abnormal_hair_follicle | 4.01266874 |
10 | MP0000427_abnormal_hair_cycle | 3.68096028 |
11 | MP0005501_abnormal_skin_physiology | 3.47991358 |
12 | MP0002254_reproductive_system_inflammat | 3.39329495 |
13 | MP0003705_abnormal_hypodermis_morpholog | 3.33927569 |
14 | MP0001216_abnormal_epidermal_layer | 2.62137956 |
15 | MP0010771_integument_phenotype | 2.33721415 |
16 | MP0004947_skin_inflammation | 2.33660523 |
17 | MP0000367_abnormal_coat/_hair | 2.33045309 |
18 | MP0004381_abnormal_hair_follicle | 2.22931124 |
19 | MP0002060_abnormal_skin_morphology | 2.16695410 |
20 | MP0001243_abnormal_dermal_layer | 2.14140312 |
21 | MP0003453_abnormal_keratinocyte_physiol | 2.10264560 |
22 | MP0002234_abnormal_pharynx_morphology | 1.57753698 |
23 | MP0009931_abnormal_skin_appearance | 1.50938918 |
24 | MP0000467_abnormal_esophagus_morphology | 1.50448963 |
25 | MP0003941_abnormal_skin_development | 1.48196385 |
26 | MP0009053_abnormal_anal_canal | 1.42403647 |
27 | MP0000762_abnormal_tongue_morphology | 1.40022711 |
28 | MP0003566_abnormal_cell_adhesion | 1.37126375 |
29 | MP0001661_extended_life_span | 1.24885031 |
30 | MP0005409_darkened_coat_color | 1.24586404 |
31 | MP0002095_abnormal_skin_pigmentation | 1.12891628 |
32 | MP0004885_abnormal_endolymph | 1.08715465 |
33 | MP0009379_abnormal_foot_pigmentation | 1.07542389 |
34 | MP0008438_abnormal_cutaneous_collagen | 1.00664254 |
35 | MP0001191_abnormal_skin_condition | 1.00235717 |
36 | MP0004185_abnormal_adipocyte_glucose | 1.00116633 |
37 | MP0004264_abnormal_extraembryonic_tissu | 0.99633412 |
38 | MP0000566_synostosis | 0.83885478 |
39 | MP0001346_abnormal_lacrimal_gland | 0.80106746 |
40 | MP0002877_abnormal_melanocyte_morpholog | 0.71456737 |
41 | MP0001340_abnormal_eyelid_morphology | 0.69800543 |
42 | MP0010030_abnormal_orbit_morphology | 0.62664441 |
43 | MP0001851_eye_inflammation | 0.60770195 |
44 | MP0003315_abnormal_perineum_morphology | 0.55739805 |
45 | MP0002009_preneoplasia | 0.55062969 |
46 | MP0000627_abnormal_mammary_gland | 0.55042722 |
47 | MP0003191_abnormal_cellular_cholesterol | 0.51709634 |
48 | MP0001849_ear_inflammation | 0.46051598 |
49 | MP0002282_abnormal_trachea_morphology | 0.45283561 |
50 | MP0001784_abnormal_fluid_regulation | 0.45173820 |
51 | MP0002970_abnormal_white_adipose | 0.44080073 |
52 | MP0003755_abnormal_palate_morphology | 0.43963401 |
53 | MP0005023_abnormal_wound_healing | 0.42725228 |
54 | MP0010352_gastrointestinal_tract_polyps | 0.40689307 |
55 | MP0002111_abnormal_tail_morphology | 0.39403133 |
56 | MP0002177_abnormal_outer_ear | 0.37433773 |
57 | MP0009384_cardiac_valve_regurgitation | 0.36476956 |
58 | MP0002166_altered_tumor_susceptibility | 0.36425679 |
59 | MP0004272_abnormal_basement_membrane | 0.34463312 |
60 | MP0005451_abnormal_body_composition | 0.33972801 |
61 | MP0003385_abnormal_body_wall | 0.33495199 |
62 | MP0000537_abnormal_urethra_morphology | 0.33431227 |
63 | MP0002006_tumorigenesis | 0.33136334 |
64 | MP0002697_abnormal_eye_size | 0.30817000 |
65 | MP0005248_abnormal_Harderian_gland | 0.27947281 |
66 | MP0000432_abnormal_head_morphology | 0.25954270 |
67 | MP0003950_abnormal_plasma_membrane | 0.24461813 |
68 | MP0005075_abnormal_melanosome_morpholog | 0.22145583 |
69 | MP0003329_amyloid_beta_deposits | 0.19903295 |
70 | MP0003300_gastrointestinal_ulcer | 0.18849744 |
71 | MP0005666_abnormal_adipose_tissue | 0.18753175 |
72 | MP0006054_spinal_hemorrhage | 0.17929435 |
73 | MP0003935_abnormal_craniofacial_develop | 0.17450378 |
74 | MP0002249_abnormal_larynx_morphology | 0.16338727 |
75 | MP0009840_abnormal_foam_cell | 0.15881318 |
76 | MP0003763_abnormal_thymus_physiology | 0.13663238 |
77 | MP0005257_abnormal_intraocular_pressure | 0.13260211 |
78 | MP0000604_amyloidosis | 0.13020446 |
79 | MP0000465_gastrointestinal_hemorrhage | 0.12948105 |
80 | MP0003638_abnormal_response/metabolism_ | 0.12044999 |
81 | MP0001730_embryonic_growth_arrest | 0.11326524 |
82 | MP0005076_abnormal_cell_differentiation | 0.11173595 |
83 | MP0001958_emphysema | 0.10890030 |
84 | MP0005375_adipose_tissue_phenotype | 0.10419583 |
85 | MP0005367_renal/urinary_system_phenotyp | 0.10382722 |
86 | MP0000516_abnormal_urinary_system | 0.10382722 |
87 | MP0005193_abnormal_anterior_eye | 0.09787401 |
88 | MP0005503_abnormal_tendon_morphology | 0.09717357 |
89 | MP0005508_abnormal_skeleton_morphology | 0.08147128 |
90 | MP0002896_abnormal_bone_mineralization | 0.07598991 |
91 | MP0000013_abnormal_adipose_tissue | 0.07474725 |
92 | MP0003448_altered_tumor_morphology | 0.07439496 |
93 | MP0000538_abnormal_urinary_bladder | 0.07314819 |
94 | MP0000428_abnormal_craniofacial_morphol | 0.07263298 |
95 | MP0003937_abnormal_limbs/digits/tail_de | 0.07082224 |
96 | MP0004742_abnormal_vestibular_system | 0.07021004 |
97 | MP0004019_abnormal_vitamin_homeostasis | 0.06677001 |
98 | MP0000751_myopathy | 0.06196883 |
99 | MP0003075_altered_response_to | 0.05842690 |
100 | MP0002233_abnormal_nose_morphology | 0.04511154 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pili torti (HP:0003777) | 9.32155174 |
2 | Nail dystrophy (HP:0008404) | 7.31485009 |
3 | Abnormal hair laboratory examination (HP:0003328) | 5.90596445 |
4 | Fine hair (HP:0002213) | 5.57172853 |
5 | Abnormality of nail color (HP:0100643) | 5.38193901 |
6 | Fragile nails (HP:0001808) | 5.26681864 |
7 | Follicular hyperkeratosis (HP:0007502) | 5.06205425 |
8 | Alopecia of scalp (HP:0002293) | 4.70034856 |
9 | Palmoplantar hyperkeratosis (HP:0000972) | 4.30424764 |
10 | Palmar hyperkeratosis (HP:0010765) | 4.05317744 |
11 | Plantar hyperkeratosis (HP:0007556) | 3.91429395 |
12 | Right ventricular cardiomyopathy (HP:0011663) | 3.75742883 |
13 | Sparse eyelashes (HP:0000653) | 3.73878181 |
14 | Onycholysis (HP:0001806) | 3.66640846 |
15 | Parakeratosis (HP:0001036) | 3.65150849 |
16 | Thick nail (HP:0001805) | 3.62065513 |
17 | Congenital, generalized hypertrichosis (HP:0004540) | 3.49802588 |
18 | Erythema (HP:0010783) | 3.33626548 |
19 | Abnormality of the frontal sinuses (HP:0002687) | 3.31598779 |
20 | Increased IgE level (HP:0003212) | 3.17280993 |
21 | Amelogenesis imperfecta (HP:0000705) | 2.98059218 |
22 | Oral leukoplakia (HP:0002745) | 2.91244110 |
23 | Erythroderma (HP:0001019) | 2.78770252 |
24 | Milia (HP:0001056) | 2.77652521 |
25 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.74510600 |
26 | Intention tremor (HP:0002080) | 2.63468069 |
27 | Curly hair (HP:0002212) | 2.59930247 |
28 | Dry hair (HP:0011359) | 2.52205535 |
29 | Aplasia cutis congenita (HP:0001057) | 2.51851858 |
30 | Neck muscle weakness (HP:0000467) | 2.36483359 |
31 | Torticollis (HP:0000473) | 2.36442494 |
32 | Ridged nail (HP:0001807) | 2.35907027 |
33 | Corneal erosion (HP:0200020) | 2.13533256 |
34 | Concave nail (HP:0001598) | 2.11459460 |
35 | Natal tooth (HP:0000695) | 2.05267312 |
36 | Hypohidrosis (HP:0000966) | 2.03280203 |
37 | Abnormal blistering of the skin (HP:0008066) | 2.00815440 |
38 | Hypotrichosis (HP:0001006) | 14.8149229 |
39 | Abnormality of hair growth rate (HP:0011363) | 11.7322164 |
40 | Slow-growing hair (HP:0002217) | 11.7322164 |
41 | Woolly hair (HP:0002224) | 11.1898380 |
42 | Brittle hair (HP:0002299) | 10.9929343 |
43 | Craniofacial dystonia (HP:0012179) | 1.99488212 |
44 | Abnormality of the parietal bone (HP:0002696) | 1.96591169 |
45 | Advanced eruption of teeth (HP:0006288) | 1.95962231 |
46 | Pruritus (HP:0000989) | 1.92939797 |
47 | Palmoplantar keratoderma (HP:0000982) | 1.92263870 |
48 | Absent eyelashes (HP:0000561) | 1.88614292 |
49 | Abnormality of the pupil (HP:0000615) | 1.84777219 |
50 | Focal dystonia (HP:0004373) | 1.82912985 |
51 | Widely patent fontanelles and sutures (HP:0004492) | 1.81616335 |
52 | Abnormality of the dental root (HP:0006486) | 1.81221001 |
53 | Taurodontia (HP:0000679) | 1.81221001 |
54 | Abnormality of permanent molar morphology (HP:0011071) | 1.81221001 |
55 | Abnormality of molar morphology (HP:0011070) | 1.78349362 |
56 | Abnormality of molar (HP:0011077) | 1.78349362 |
57 | Abnormality of dental color (HP:0011073) | 1.77778043 |
58 | Hyporeflexia of lower limbs (HP:0002600) | 1.76889028 |
59 | Ventricular tachycardia (HP:0004756) | 1.76612866 |
60 | Difficulty walking (HP:0002355) | 1.72871310 |
61 | Recurrent corneal erosions (HP:0000495) | 1.69968435 |
62 | Ventricular fibrillation (HP:0001663) | 1.61051553 |
63 | Conjunctival hamartoma (HP:0100780) | 1.58850171 |
64 | Abnormality of the dental pulp (HP:0006479) | 1.58105518 |
65 | Amniotic constriction ring (HP:0009775) | 1.57997475 |
66 | Abnormality of placental membranes (HP:0011409) | 1.57997475 |
67 | Lip pit (HP:0100267) | 1.56050161 |
68 | Blepharitis (HP:0000498) | 1.52505400 |
69 | Keratoconjunctivitis sicca (HP:0001097) | 1.46249199 |
70 | Acanthosis nigricans (HP:0000956) | 1.45365806 |
71 | Craniofacial hyperostosis (HP:0004493) | 1.44146183 |
72 | Autoamputation (HP:0001218) | 1.41312436 |
73 | Heterogeneous (HP:0001425) | 1.37252270 |
74 | Achilles tendon contracture (HP:0001771) | 1.34337611 |
75 | Distal lower limb muscle weakness (HP:0009053) | 1.31575393 |
76 | Round ear (HP:0100830) | 1.29782876 |
77 | Ectropion (HP:0000656) | 1.29198415 |
78 | Gangrene (HP:0100758) | 1.29035079 |
79 | Widely spaced teeth (HP:0000687) | 1.28605677 |
80 | Keratoconjunctivitis (HP:0001096) | 1.28211103 |
81 | Abnormality of the Achilles tendon (HP:0005109) | 1.27964017 |
82 | Carious teeth (HP:0000670) | 1.26494180 |
83 | Sudden death (HP:0001699) | 1.25628412 |
84 | Atrophic scars (HP:0001075) | 1.25012975 |
85 | Lack of skin elasticity (HP:0100679) | 1.23746029 |
86 | Fatigable weakness (HP:0003473) | 1.20861227 |
87 | Abnormality of the neuromuscular junction (HP:0003398) | 1.20861227 |
88 | Rectal prolapse (HP:0002035) | 1.17982787 |
89 | Variable expressivity (HP:0003828) | 1.17592596 |
90 | Wide cranial sutures (HP:0010537) | 1.16891843 |
91 | Abnormality of the fingernails (HP:0001231) | 1.16365037 |
92 | Increased connective tissue (HP:0009025) | 1.15479441 |
93 | Hypoplastic labia majora (HP:0000059) | 1.14303886 |
94 | Sparse scalp hair (HP:0002209) | 1.13105732 |
95 | Type 1 muscle fiber predominance (HP:0003803) | 1.11779691 |
96 | Bronchomalacia (HP:0002780) | 1.08888004 |
97 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.08251370 |
98 | Selective tooth agenesis (HP:0001592) | 1.07623303 |
99 | Anonychia (HP:0001798) | 1.06661796 |
100 | Cranial hyperostosis (HP:0004437) | 1.05652218 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 4.21303912 |
2 | MAPKAPK3 | 3.77516423 |
3 | FER | 3.35783760 |
4 | ERN1 | 3.34450402 |
5 | LATS1 | 3.24383582 |
6 | EPHB2 | 3.09685083 |
7 | MAP3K6 | 2.96040511 |
8 | MAP3K2 | 2.85390655 |
9 | FGFR2 | 2.78234408 |
10 | MAP3K3 | 2.69468883 |
11 | TAOK1 | 2.56268470 |
12 | TRIB3 | 2.20741300 |
13 | RPS6KB2 | 1.96330821 |
14 | TTN | 1.87321819 |
15 | MAP2K6 | 1.86630304 |
16 | BCR | 1.75944962 |
17 | LATS2 | 1.75368242 |
18 | FGFR1 | 1.71825030 |
19 | MAP3K11 | 1.70564999 |
20 | PIK3CG | 1.65629659 |
21 | FGFR3 | 1.55466139 |
22 | MST1R | 1.44841871 |
23 | CDK6 | 1.42160915 |
24 | KSR2 | 1.35671021 |
25 | PBK | 1.31338572 |
26 | NME1 | 1.27986953 |
27 | EPHB1 | 1.26469568 |
28 | EEF2K | 1.24113503 |
29 | PDGFRA | 1.18507122 |
30 | MAP3K1 | 1.17076214 |
31 | PTK6 | 1.16424609 |
32 | RIPK1 | 1.13800225 |
33 | LRRK2 | 1.06962638 |
34 | MAP3K7 | 1.06566205 |
35 | MAP3K9 | 1.02154313 |
36 | MAP2K4 | 1.01732431 |
37 | MAP2K3 | 1.00581532 |
38 | BMX | 0.97635175 |
39 | ERBB4 | 0.97460361 |
40 | PKN2 | 0.93461742 |
41 | MAPKAPK2 | 0.92725846 |
42 | ERBB3 | 0.89881798 |
43 | MET | 0.84426583 |
44 | FGFR4 | 0.80439233 |
45 | MAP2K1 | 0.80267743 |
46 | PAK3 | 0.75994388 |
47 | SIK1 | 0.74371191 |
48 | NEK1 | 0.73512936 |
49 | STK38 | 0.73254102 |
50 | FRK | 0.73253541 |
51 | DYRK1B | 0.72730223 |
52 | TRPM7 | 0.71980827 |
53 | DDR2 | 0.70182485 |
54 | NTRK2 | 0.70169340 |
55 | BLK | 0.69015784 |
56 | CDK19 | 0.67916355 |
57 | PRKD1 | 0.66914597 |
58 | MST4 | 0.65787598 |
59 | PTK2 | 0.65368001 |
60 | RPS6KA4 | 0.63946924 |
61 | TGFBR1 | 0.63823012 |
62 | STK38L | 0.59872479 |
63 | ERBB2 | 0.58538655 |
64 | TYRO3 | 0.57652652 |
65 | MAP3K5 | 0.57333600 |
66 | TESK1 | 0.56849045 |
67 | PRKCH | 0.56502684 |
68 | PIM2 | 0.54393655 |
69 | CSNK1A1L | 0.53441245 |
70 | PAK4 | 0.52734636 |
71 | CSNK1E | 0.51533290 |
72 | RET | 0.50787352 |
73 | SCYL2 | 0.50137971 |
74 | ALK | 0.47347678 |
75 | GSK3A | 0.46806839 |
76 | CSNK1G1 | 0.42975994 |
77 | STK3 | 0.41745626 |
78 | PAK6 | 0.40670019 |
79 | EPHA4 | 0.40260759 |
80 | LIMK1 | 0.39699454 |
81 | CSNK1G3 | 0.38432203 |
82 | JAK2 | 0.37751090 |
83 | MAPK12 | 0.37230363 |
84 | PRKCI | 0.35484000 |
85 | MARK3 | 0.34028710 |
86 | PAK2 | 0.33781012 |
87 | RPS6KA1 | 0.32955210 |
88 | MINK1 | 0.32699532 |
89 | ILK | 0.32228364 |
90 | CSNK1D | 0.31035813 |
91 | FYN | 0.29678940 |
92 | CSNK1G2 | 0.29623940 |
93 | ROCK2 | 0.29597644 |
94 | KSR1 | 0.29468301 |
95 | PDPK1 | 0.28573283 |
96 | SRC | 0.28562400 |
97 | MAP3K10 | 0.28299459 |
98 | JAK1 | 0.27324695 |
99 | MAP2K2 | 0.26414452 |
100 | PRKACG | 0.25988512 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 4.25585755 |
2 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 4.25530275 |
3 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.65927452 |
4 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.43156418 |
5 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.32846279 |
6 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.26758753 |
7 | Melanogenesis_Homo sapiens_hsa04916 | 1.74544605 |
8 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.71988773 |
9 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.68121489 |
10 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.67090628 |
11 | Axon guidance_Homo sapiens_hsa04360 | 1.60330639 |
12 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.56653860 |
13 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.55783161 |
14 | Bladder cancer_Homo sapiens_hsa05219 | 1.51903990 |
15 | Glioma_Homo sapiens_hsa05214 | 1.48580584 |
16 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.46819763 |
17 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.46311346 |
18 | Thyroid cancer_Homo sapiens_hsa05216 | 1.43459070 |
19 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.43227796 |
20 | Histidine metabolism_Homo sapiens_hsa00340 | 1.39543710 |
21 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.38820316 |
22 | Long-term potentiation_Homo sapiens_hsa04720 | 1.37676585 |
23 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.28638118 |
24 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.28309377 |
25 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.27843090 |
26 | Mineral absorption_Homo sapiens_hsa04978 | 1.26666635 |
27 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.25722620 |
28 | Tight junction_Homo sapiens_hsa04530 | 1.18519272 |
29 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.08803603 |
30 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.06626286 |
31 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.04221311 |
32 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.01942871 |
33 | Long-term depression_Homo sapiens_hsa04730 | 1.01204820 |
34 | Adherens junction_Homo sapiens_hsa04520 | 1.00196787 |
35 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.99392725 |
36 | Endometrial cancer_Homo sapiens_hsa05213 | 0.98948203 |
37 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.97077497 |
38 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.95506262 |
39 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.93856993 |
40 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.93223469 |
41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.91330306 |
42 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.89532180 |
43 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.86743982 |
44 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.84394551 |
45 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.83151523 |
46 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.81795099 |
47 | Pertussis_Homo sapiens_hsa05133 | 0.81186855 |
48 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.80913464 |
49 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.79335061 |
50 | Renin secretion_Homo sapiens_hsa04924 | 0.78662163 |
51 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.77842894 |
52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.74474892 |
53 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.72583354 |
54 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.72110040 |
55 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.71075963 |
56 | Amoebiasis_Homo sapiens_hsa05146 | 0.70416834 |
57 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.70378282 |
58 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69992091 |
59 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.68015586 |
60 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.67917478 |
61 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.67895045 |
62 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.67865362 |
63 | Gap junction_Homo sapiens_hsa04540 | 0.65706408 |
64 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.64692285 |
65 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61025592 |
66 | Insulin resistance_Homo sapiens_hsa04931 | 0.60891577 |
67 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.60356810 |
68 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.60324490 |
69 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.58501691 |
70 | Focal adhesion_Homo sapiens_hsa04510 | 0.58410028 |
71 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.58215149 |
72 | Hepatitis C_Homo sapiens_hsa05160 | 0.57988134 |
73 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.57602506 |
74 | Platelet activation_Homo sapiens_hsa04611 | 0.57195784 |
75 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.56359616 |
76 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.56288905 |
77 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.56169629 |
78 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.56101281 |
79 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.55810430 |
80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.55721740 |
81 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.54350655 |
82 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.53018651 |
83 | Salivary secretion_Homo sapiens_hsa04970 | 0.48187905 |
84 | Salmonella infection_Homo sapiens_hsa05132 | 0.48151759 |
85 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.47761929 |
86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47531723 |
87 | Melanoma_Homo sapiens_hsa05218 | 0.46817209 |
88 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.45653823 |
89 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45296136 |
90 | Phototransduction_Homo sapiens_hsa04744 | 0.44672414 |
91 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44590341 |
92 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.44060595 |
93 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.42994241 |
94 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.42875128 |
95 | Prion diseases_Homo sapiens_hsa05020 | 0.41715494 |
96 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.41638409 |
97 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37219077 |
98 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.35078265 |
99 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.34862934 |
100 | Prostate cancer_Homo sapiens_hsa05215 | 0.34055542 |