KRTAP26-1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1adhesion of symbiont to host cell (GO:0044650)9.94864613
2virion attachment to host cell (GO:0019062)9.94864613
3citrulline biosynthetic process (GO:0019240)8.97173610
4peptide cross-linking (GO:0018149)8.42740227
5adhesion of symbiont to host (GO:0044406)8.41225810
6hair follicle morphogenesis (GO:0031069)8.39996527
7intermediate filament cytoskeleton organization (GO:0045104)6.61325777
8intermediate filament-based process (GO:0045103)6.40058408
9cell wall macromolecule metabolic process (GO:0044036)6.32347426
10cell wall macromolecule catabolic process (GO:0016998)6.32347426
11epidermis development (GO:0008544)6.12298386
12citrulline metabolic process (GO:0000052)5.90053218
13keratinocyte differentiation (GO:0030216)5.76938791
14establishment of skin barrier (GO:0061436)5.72401965
15negative regulation of stress fiber assembly (GO:0051497)5.43896917
16molting cycle process (GO:0022404)5.42374934
17hair cycle process (GO:0022405)5.42374934
18regulation of water loss via skin (GO:0033561)5.06951254
19bundle of His cell to Purkinje myocyte communication (GO:0086069)5.02785260
20peptidyl-arginine modification (GO:0018195)5.01331072
21skin morphogenesis (GO:0043589)4.75283606
22hemidesmosome assembly (GO:0031581)4.50678418
23epidermal cell differentiation (GO:0009913)4.50050445
24keratinocyte development (GO:0003334)4.05601566
25negative regulation of actin filament bundle assembly (GO:0032232)4.05361428
26hair cycle (GO:0042633)35.0347827
27molting cycle (GO:0042303)35.0347827
28linoleic acid metabolic process (GO:0043651)3.97323880
29seminiferous tubule development (GO:0072520)3.96906742
30regulation of female receptivity (GO:0045924)3.94842152
31tooth mineralization (GO:0034505)3.92369346
32positive regulation of lamellipodium assembly (GO:0010592)3.90848821
33hindbrain development (GO:0030902)3.86198387
34long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.70888339
35cellular response to ATP (GO:0071318)3.55527183
36fatty-acyl-CoA biosynthetic process (GO:0046949)3.45908438
37multicellular organismal water homeostasis (GO:0050891)3.41056162
38lateral sprouting from an epithelium (GO:0060601)3.38826212
39negative regulation of keratinocyte proliferation (GO:0010839)3.35566995
40retinol metabolic process (GO:0042572)3.32912655
41regulation of keratinocyte differentiation (GO:0045616)3.28536977
42phosphatidylinositol acyl-chain remodeling (GO:0036149)3.28319176
43female mating behavior (GO:0060180)3.25578061
44long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.24990945
45hair follicle development (GO:0001942)3.22432396
46positive regulation of hair cycle (GO:0042635)3.21741704
47positive regulation of hair follicle development (GO:0051798)3.21741704
48aggressive behavior (GO:0002118)3.21307415
49positive regulation of lamellipodium organization (GO:1902745)3.19575179
50negative regulation of smooth muscle cell differentiation (GO:0051151)3.17684086
51negative regulation of establishment of protein localization to plasma membrane (GO:0090005)3.16051508
52regulation of mesoderm development (GO:2000380)3.14708789
53cilium or flagellum-dependent cell motility (GO:0001539)3.10205836
54acyl-CoA biosynthetic process (GO:0071616)3.05745475
55thioester biosynthetic process (GO:0035384)3.05745475
56positive regulation of glomerulus development (GO:0090193)3.02194494
57phosphatidylserine acyl-chain remodeling (GO:0036150)2.98754930
58regulation of hair follicle development (GO:0051797)2.97383218
59water homeostasis (GO:0030104)2.96637025
60somite development (GO:0061053)2.94468992
61epithelium development (GO:0060429)2.90905278
62bone trabecula formation (GO:0060346)2.90486290
63regulation of sequestering of triglyceride (GO:0010889)2.85270824
64RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.83486341
65single strand break repair (GO:0000012)2.82965335
66positive regulation of meiotic cell cycle (GO:0051446)2.82342379
67phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.79920122
68fatty-acyl-CoA metabolic process (GO:0035337)2.77992212
69positive regulation of antigen processing and presentation (GO:0002579)2.74396479
70DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.73900290
71gap junction assembly (GO:0016264)2.70737323
72regulation of triglyceride catabolic process (GO:0010896)2.69748299
73positive regulation of epidermis development (GO:0045684)2.68528629
74regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.66963522
75primary alcohol metabolic process (GO:0034308)2.64132929
76fatty acid elongation (GO:0030497)2.63688481
77regulation of hair cycle (GO:0042634)2.63683061
78defense response to fungus (GO:0050832)2.63234573
79regulation of antigen processing and presentation (GO:0002577)2.60861860
80negative regulation of protein localization to plasma membrane (GO:1903077)2.56729597
81disruption of cells of other organism (GO:0044364)2.56574020
82killing of cells of other organism (GO:0031640)2.56574020
83regulation of epidermal cell differentiation (GO:0045604)2.56148236
84atrioventricular valve morphogenesis (GO:0003181)2.52467006
85ectoderm development (GO:0007398)2.52172981
86triglyceride biosynthetic process (GO:0019432)2.46891428
87positive regulation of cAMP-mediated signaling (GO:0043950)2.46713151
88regulation of glomerulus development (GO:0090192)2.46152536
89regulation of epidermis development (GO:0045682)2.44865948
90epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.44077267
91prostate gland growth (GO:0060736)2.41934744
92positive regulation of T-helper 1 type immune response (GO:0002827)2.41919584
93uterus development (GO:0060065)2.39920522
94axonemal dynein complex assembly (GO:0070286)2.39201192
95protein polyglutamylation (GO:0018095)2.39094601
96immunoglobulin mediated immune response (GO:0016064)2.38539238
97regulation of rhodopsin mediated signaling pathway (GO:0022400)2.36883083
98neutral lipid biosynthetic process (GO:0046460)2.36584405
99acylglycerol biosynthetic process (GO:0046463)2.36584405
100regulation of inositol phosphate biosynthetic process (GO:0010919)2.36151656
101endothelium development (GO:0003158)2.34013081
102ventricular cardiac muscle cell action potential (GO:0086005)2.33054742
103DNA damage response, signal transduction resulting in transcription (GO:0042772)2.32625692
104regulation of defense response to virus by host (GO:0050691)2.32476327
105regulation of mesenchymal cell apoptotic process (GO:2001053)2.31482682
106positive regulation of organelle assembly (GO:1902117)2.29992923
107positive regulation of chemokine secretion (GO:0090197)2.29439665
108spinal cord development (GO:0021510)2.26948374
109positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.26375465
110embryonic skeletal joint morphogenesis (GO:0060272)2.25636025
111wound healing, spreading of epidermal cells (GO:0035313)2.24689740
112lymph vessel development (GO:0001945)2.24131836
113negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.23666429
114nitric oxide mediated signal transduction (GO:0007263)2.23011023
115rhodopsin mediated signaling pathway (GO:0016056)2.22752431
116phosphatidylserine metabolic process (GO:0006658)2.22493626
117water-soluble vitamin biosynthetic process (GO:0042364)2.21050634
118DNA deamination (GO:0045006)2.20901385
119regulation of ruffle assembly (GO:1900027)2.20569454
120positive regulation of epidermal cell differentiation (GO:0045606)2.19981889
121negative regulation of cell fate specification (GO:0009996)2.18870086
122cellular response to interferon-beta (GO:0035458)2.18658888
123positive regulation of monocyte chemotaxis (GO:0090026)2.17322328
124cell surface receptor signaling pathway involved in heart development (GO:0061311)2.17196719
125epithelial cell maturation (GO:0002070)2.17045663
126phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.16812689
127interferon-gamma secretion (GO:0072643)2.15870189
128positive thymic T cell selection (GO:0045059)2.15262236
129organ formation (GO:0048645)2.13914107
130activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.13685378
131magnesium ion transport (GO:0015693)2.13092354
132regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.12241664
133phosphatidylethanolamine biosynthetic process (GO:0006646)2.09471252
134cranial suture morphogenesis (GO:0060363)2.08394221
135cellular ketone body metabolic process (GO:0046950)2.06683330
136indolalkylamine catabolic process (GO:0046218)2.04761754
137tryptophan catabolic process (GO:0006569)2.04761754
138skin development (GO:0043588)2.04596281
139aging (GO:0007568)2.01508416
140myotube differentiation (GO:0014902)2.00618963
141intermediate filament organization (GO:0045109)12.0890814
142keratinization (GO:0031424)11.6256873
143desmosome organization (GO:0002934)10.0118849
144negative regulation of epidermis development (GO:0045683)1.97467380
145regulation of keratinocyte proliferation (GO:0010837)1.95804748
146regulation of heart rate by cardiac conduction (GO:0086091)1.93273197
147outflow tract septum morphogenesis (GO:0003148)1.92576386
148epithelial cell-cell adhesion (GO:0090136)1.92188203
149regulation of cardioblast differentiation (GO:0051890)1.92087890
150phosphatidylcholine acyl-chain remodeling (GO:0036151)1.91535641
151cytoskeletal anchoring at plasma membrane (GO:0007016)1.89454181
152ephrin receptor signaling pathway (GO:0048013)1.88930299
153planar cell polarity pathway involved in neural tube closure (GO:0090179)1.86071557
154cell communication involved in cardiac conduction (GO:0086065)1.85834869
155regulation of Wnt signaling pathway involved in heart development (GO:0003307)1.80339201
156non-canonical Wnt signaling pathway (GO:0035567)1.74651057
157regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901211.71188705
158establishment of tissue polarity (GO:0007164)1.70428274
159establishment of planar polarity (GO:0001736)1.70428274
160regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)1.69390749
161primary alcohol catabolic process (GO:0034310)1.68796283
162cardiac right ventricle morphogenesis (GO:0003215)1.67332034
163regulation of cardioblast proliferation (GO:0003264)1.66196758
164regulation of secondary heart field cardioblast proliferation (GO:0003266)1.66196758
165very long-chain fatty acid metabolic process (GO:0000038)1.65513537
166keratinocyte proliferation (GO:0043616)1.64100809
167cell-substrate junction assembly (GO:0007044)1.62775836
168alditol phosphate metabolic process (GO:0052646)1.62706799
169G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071991.62532092
170coronary vasculature morphogenesis (GO:0060977)1.60348107
171lung-associated mesenchyme development (GO:0060484)1.60316764
172negative regulation of epidermal cell differentiation (GO:0045605)1.58487084
173wound healing, spreading of cells (GO:0044319)1.56778258
174craniofacial suture morphogenesis (GO:0097094)1.54228290

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.68491922
2CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human4.97234048
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.81778376
4P63_26484246_Chip-Seq_KERATINOCYTES_Human3.56212783
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.71437226
6CTCF_20526341_ChIP-Seq_ESCs_Human2.39592542
7BMI1_19503595_ChIP-Seq_MEFsC_Mouse2.22118698
8NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse2.21434986
9TP63_17297297_ChIP-ChIP_HaCaT_Human12.2643918
10STAT6_21828071_ChIP-Seq_BEAS2B_Human1.96730408
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.91889378
12IRF8_22096565_ChIP-ChIP_GC-B_Human1.88584373
13E2F1_20622854_ChIP-Seq_HELA_Human1.86103437
14TAF2_19829295_ChIP-Seq_ESCs_Human1.85807333
15VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.76957514
16GBX2_23144817_ChIP-Seq_PC3_Human1.76480643
17P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.76334324
18CSB_26484114_Chip-Seq_FIBROBLAST_Human1.75076732
19NANOG_20526341_ChIP-Seq_ESCs_Human1.74616904
20EGR1_19032775_ChIP-ChIP_M12_Human1.73555040
21RNF2_27304074_Chip-Seq_NSC_Mouse1.70996374
22BP1_19119308_ChIP-ChIP_Hs578T_Human1.68420671
23SOX9_24532713_ChIP-Seq_HFSC_Mouse1.67022935
24TP53_16413492_ChIP-PET_HCT116_Human1.66214365
25CTCF_27219007_Chip-Seq_Bcells_Human1.66198280
26TP53_20018659_ChIP-ChIP_R1E_Mouse1.62964959
27P53_21459846_ChIP-Seq_SAOS-2_Human1.59855720
28BCL6_27268052_Chip-Seq_Bcells_Human1.54658934
29YY1_22570637_ChIP-Seq_MALME-3M_Human1.52148184
30MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse1.50732045
31DNAJC2_21179169_ChIP-ChIP_NT2_Human1.50512732
32TP63_22573176_ChIP-Seq_HFKS_Human1.48602602
33FOXO3_23340844_ChIP-Seq_DLD1_Human1.46761810
34RACK7_27058665_Chip-Seq_MCF-7_Human1.44881393
35LXR_22292898_ChIP-Seq_THP-1_Human1.42983141
36EGR1_23403033_ChIP-Seq_LIVER_Mouse1.42949128
37SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.42889088
38SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.42889088
39FOXA1_25329375_ChIP-Seq_VCAP_Human1.42282449
40IGF1R_20145208_ChIP-Seq_DFB_Human1.40783185
41BCOR_27268052_Chip-Seq_Bcells_Human1.40694817
42* ERG_20517297_ChIP-Seq_VCAP_Human1.37772682
43IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.36669785
44UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.34945505
45CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.34941837
46AUTS2_25519132_ChIP-Seq_293T-REX_Human1.33135736
47SUZ12_27294783_Chip-Seq_ESCs_Mouse1.33043607
48ZNF274_21170338_ChIP-Seq_K562_Hela1.32925860
49FLI1_27457419_Chip-Seq_LIVER_Mouse1.32365025
50ESR1_21235772_ChIP-Seq_MCF-7_Human1.32129439
51EZH2_22144423_ChIP-Seq_EOC_Human1.30834316
52SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.30612094
53ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.29959131
54RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29715342
55AR_25329375_ChIP-Seq_VCAP_Human1.29611466
56ARNT_22903824_ChIP-Seq_MCF-7_Human1.27878108
57PHF8_20622854_ChIP-Seq_HELA_Human1.27052759
58ATF3_27146783_Chip-Seq_COLON_Human1.26832950
59SOX2_19829295_ChIP-Seq_ESCs_Human1.25319518
60NANOG_19829295_ChIP-Seq_ESCs_Human1.25319518
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25225822
62SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.24575584
63RARG_19884340_ChIP-ChIP_MEFs_Mouse1.24071251
64JARID2_20075857_ChIP-Seq_MESCs_Mouse1.23881598
65IKZF1_21737484_ChIP-ChIP_HCT116_Human1.23825041
66CBP_20019798_ChIP-Seq_JUKART_Human1.23824008
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23824008
68EED_16625203_ChIP-ChIP_MESCs_Mouse1.23754809
69ESR2_21235772_ChIP-Seq_MCF-7_Human1.23570636
70AHR_22903824_ChIP-Seq_MCF-7_Human1.22993630
71E2F1_17053090_ChIP-ChIP_MCF-7_Human1.20218671
72P68_20966046_ChIP-Seq_HELA_Human1.19859123
73ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19792888
74PIAS1_25552417_ChIP-Seq_VCAP_Human1.19736631
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.19568981
76CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.19519565
77OCT4_20526341_ChIP-Seq_ESCs_Human1.19424710
78NCOR_22424771_ChIP-Seq_293T_Human1.19020149
79ELF1_20517297_ChIP-Seq_JURKAT_Human1.18025191
80JARID2_20064375_ChIP-Seq_MESCs_Mouse1.17432658
81CEBPB_22108803_ChIP-Seq_LS180_Human1.16941720
82ELK4_26923725_Chip-Seq_MESODERM_Mouse1.16635420
83PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16461852
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.16403872
85AR_20517297_ChIP-Seq_VCAP_Human1.16104091
86PCGF2_27294783_Chip-Seq_NPCs_Mouse1.14070797
87STAT1_20625510_ChIP-Seq_HELA_Human1.13532457
88KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13129957
89RAC3_21632823_ChIP-Seq_H3396_Human1.11895274
90GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11674380
91HTT_18923047_ChIP-ChIP_STHdh_Human1.11289785
92SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.09651212
93CBX2_27304074_Chip-Seq_ESCs_Mouse1.09623639
94KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.09531146
95KAP1_22055183_ChIP-Seq_ESCs_Mouse1.08518206
96TP63_23658742_ChIP-Seq_EP156T_Human1.07651370
97TRIM28_21343339_ChIP-Seq_HEK293_Human1.07147582
98BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07119575
99SMC4_20622854_ChIP-Seq_HELA_Human1.06916683
100EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.06844662
101NFE2_27457419_Chip-Seq_LIVER_Mouse1.06773541
102SOX2_21211035_ChIP-Seq_LN229_Human1.06675111
103P300_27268052_Chip-Seq_Bcells_Human1.06644744
104PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06527857
105CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05395945
106JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05328463
107UBF1/2_26484160_Chip-Seq_HMECs_Human1.05024492
108EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.04604249
109OCT1_27270436_Chip-Seq_PROSTATE_Human1.04395688
110PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.03869329
111GATA3_24758297_ChIP-Seq_MCF-7_Human1.03751395
112IRF8_21731497_ChIP-ChIP_J774_Mouse1.03525513
113FUS_26573619_Chip-Seq_HEK293_Human1.03432934
114FOXH1_21741376_ChIP-Seq_EPCs_Human1.02486780
115JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02371135
116CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.02316109
117TP53_18474530_ChIP-ChIP_U2OS_Human1.01916584
118ERG_21242973_ChIP-ChIP_JURKAT_Human1.01864791
119CDX2_19796622_ChIP-Seq_MESCs_Mouse1.00463385
120TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00139605
121P300_27058665_Chip-Seq_ZR-75-30cells_Human0.99743999
122GATA4_25053715_ChIP-Seq_YYC3_Human0.99564418
123AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99428603
124GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.98687700
125FOXH1_21741376_ChIP-Seq_ESCs_Human0.98122559
126SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97746507
127POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96685011
128RING1B_27294783_Chip-Seq_ESCs_Mouse0.95780055
129GATA3_21878914_ChIP-Seq_MCF-7_Human0.94837795
130RXRA_24833708_ChIP-Seq_LIVER_Mouse0.94431225
131SPI1_20517297_ChIP-Seq_HL60_Human0.93811352
132EWS_26573619_Chip-Seq_HEK293_Human0.92684185
133KLF5_25053715_ChIP-Seq_YYC3_Human0.92494302
134EZH2_27294783_Chip-Seq_ESCs_Mouse0.92390503
135* SA1_27219007_Chip-Seq_ERYTHROID_Human0.91642552
136GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.90900048
137VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90363115
138RNF2_27304074_Chip-Seq_ESCs_Mouse0.90313613
139GATA6_21074721_ChIP-Seq_CACO-2_Human0.89789092
140TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.89340240
141GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.89174124
142P53_22387025_ChIP-Seq_ESCs_Mouse0.88934996
143VDR_22108803_ChIP-Seq_LS180_Human0.88853427
144AR_21572438_ChIP-Seq_LNCaP_Human0.88791778
145SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.88476253
146RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.87526171
147RUNX1_27514584_Chip-Seq_MCF-7_Human0.85816990
148EZH2_27304074_Chip-Seq_ESCs_Mouse0.85041455
149CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.84955951
150ZNF263_19887448_ChIP-Seq_K562_Human0.84926100
151BMI1_23680149_ChIP-Seq_NPCS_Mouse0.83828243
152TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82575501
153SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.82181518
154SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.81227752
155SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.80549327
156RXR_22108803_ChIP-Seq_LS180_Human0.80335601
157SOX2_20726797_ChIP-Seq_SW620_Human0.80217441
158RNF2_18974828_ChIP-Seq_MESCs_Mouse0.79855460
159EZH2_18974828_ChIP-Seq_MESCs_Mouse0.79855460
160FOXA1_27270436_Chip-Seq_PROSTATE_Human0.76148968

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000579_abnormal_nail_morphology7.57274602
2MP0002098_abnormal_vibrissa_morphology7.35263118
3MP0000647_abnormal_sebaceous_gland6.57584801
4MP0002796_impaired_skin_barrier5.97640658
5MP0005275_abnormal_skin_tensile5.17576250
6MP0010234_abnormal_vibrissa_follicle5.02385341
7MP0000383_abnormal_hair_follicle4.51886739
8MP0000377_abnormal_hair_follicle4.10871623
9MP0010678_abnormal_skin_adnexa3.98176502
10MP0005501_abnormal_skin_physiology3.71666610
11MP0005646_abnormal_pituitary_gland3.65530883
12MP0003705_abnormal_hypodermis_morpholog3.63630199
13MP0000427_abnormal_hair_cycle3.52236040
14MP0002254_reproductive_system_inflammat3.18929308
15MP0001216_abnormal_epidermal_layer2.66242740
16MP0004381_abnormal_hair_follicle2.40386717
17MP0000367_abnormal_coat/_hair2.39202572
18MP0010771_integument_phenotype2.32225478
19MP0004947_skin_inflammation2.27704076
20MP0001986_abnormal_taste_sensitivity2.22612213
21MP0001243_abnormal_dermal_layer2.18522054
22MP0002060_abnormal_skin_morphology2.16037289
23MP0003453_abnormal_keratinocyte_physiol2.10911423
24MP0002234_abnormal_pharynx_morphology2.07097030
25MP0002138_abnormal_hepatobiliary_system2.06419466
26MP0009780_abnormal_chondrocyte_physiolo1.90329970
27MP0005647_abnormal_sex_gland1.70896429
28MP0003646_muscle_fatigue1.68537031
29MP0003283_abnormal_digestive_organ1.66010948
30MP0000467_abnormal_esophagus_morphology1.61950862
31MP0001968_abnormal_touch/_nociception1.54610555
32MP0002876_abnormal_thyroid_physiology1.50020948
33MP0009931_abnormal_skin_appearance1.49675403
34MP0009053_abnormal_anal_canal1.48800906
35MP0000762_abnormal_tongue_morphology1.46352691
36MP0005377_hearing/vestibular/ear_phenot1.42808429
37MP0003878_abnormal_ear_physiology1.42808429
38MP0003566_abnormal_cell_adhesion1.39749941
39MP0002735_abnormal_chemical_nociception1.35463164
40MP0005187_abnormal_penis_morphology1.29499962
41MP0003941_abnormal_skin_development1.28407919
42MP0005409_darkened_coat_color1.19040217
43MP0008775_abnormal_heart_ventricle1.12581300
44MP0004145_abnormal_muscle_electrophysio1.09853249
45MP0001919_abnormal_reproductive_system1.07376243
46MP0005220_abnormal_exocrine_pancreas0.98239353
47MP0001191_abnormal_skin_condition0.95586856
48MP0002102_abnormal_ear_morphology0.94167974
49MP0004885_abnormal_endolymph0.93775715
50MP0005389_reproductive_system_phenotype0.92554798
51MP0001666_abnormal_nutrient_absorption0.88760691
52MP0004185_abnormal_adipocyte_glucose0.86771350
53MP0002095_abnormal_skin_pigmentation0.84300629
54MP0003195_calcinosis0.83564126
55MP0006035_abnormal_mitochondrial_morpho0.82616650
56MP0004264_abnormal_extraembryonic_tissu0.82561491
57MP0002139_abnormal_hepatobiliary_system0.81153333
58MP0004782_abnormal_surfactant_physiolog0.79968033
59MP0004130_abnormal_muscle_cell0.79430167
60MP0002837_dystrophic_cardiac_calcinosis0.78715650
61MP0003119_abnormal_digestive_system0.78578328
62MP0001664_abnormal_digestion0.78474087
63MP0004043_abnormal_pH_regulation0.75568118
64MP0001851_eye_inflammation0.75069670
65MP0003724_increased_susceptibility_to0.74302043
66MP0003303_peritoneal_inflammation0.73311708
67MP0002733_abnormal_thermal_nociception0.72308909
68MP0005464_abnormal_platelet_physiology0.71104905
69MP0001873_stomach_inflammation0.70399058
70MP0001340_abnormal_eyelid_morphology0.70325993
71MP0002877_abnormal_melanocyte_morpholog0.69671284
72MP0003315_abnormal_perineum_morphology0.69449928
73MP0001346_abnormal_lacrimal_gland0.66634097
74MP0008438_abnormal_cutaneous_collagen0.66234651
75MP0003868_abnormal_feces_composition0.63672066
76MP0001661_extended_life_span0.63071657
77MP0002282_abnormal_trachea_morphology0.62363461
78MP0010030_abnormal_orbit_morphology0.60119209
79MP0001764_abnormal_homeostasis0.60004664
80MP0000230_abnormal_systemic_arterial0.59439786
81MP0000613_abnormal_salivary_gland0.58887414
82MP0001849_ear_inflammation0.57117516
83MP0000566_synostosis0.56946715
84MP0008995_early_reproductive_senescence0.55575113
85MP0000627_abnormal_mammary_gland0.55219294
86MP0005551_abnormal_eye_electrophysiolog0.53990338
87MP0002249_abnormal_larynx_morphology0.53942985
88MP0005670_abnormal_white_adipose0.52533151
89MP0001440_abnormal_grooming_behavior0.50952207
90MP0005174_abnormal_tail_pigmentation0.50876015
91MP0003191_abnormal_cellular_cholesterol0.50373916
92MP0002148_abnormal_hypersensitivity_rea0.50109402
93MP0003866_abnormal_defecation0.49652284
94MP0003755_abnormal_palate_morphology0.48702209
95MP0008872_abnormal_physiological_respon0.48696511
96MP0001784_abnormal_fluid_regulation0.45210882
97MP0009379_abnormal_foot_pigmentation0.44399963
98MP0002970_abnormal_white_adipose0.43509308
99MP0004484_altered_response_of0.43059415
100MP0005023_abnormal_wound_healing0.42908235
101MP0005451_abnormal_body_composition0.42436805
102MP0002111_abnormal_tail_morphology0.42340343
103MP0001663_abnormal_digestive_system0.41362247
104MP0001485_abnormal_pinna_reflex0.39463575
105MP0002160_abnormal_reproductive_system0.39026325
106MP0005075_abnormal_melanosome_morpholog0.37143244
107MP0000470_abnormal_stomach_morphology0.36807064
108MP0002177_abnormal_outer_ear0.36800021
109MP0001533_abnormal_skeleton_physiology0.35806954
110MP0003718_maternal_effect0.35685526
111MP0000678_abnormal_parathyroid_gland0.34850477
112MP0003385_abnormal_body_wall0.34499092
113MP0006072_abnormal_retinal_apoptosis0.34439059
114MP0003436_decreased_susceptibility_to0.32983447
115MP0001293_anophthalmia0.32015991
116MP0004272_abnormal_basement_membrane0.30710841
117MP0000631_abnormal_neuroendocrine_gland0.30610406
118MP0001501_abnormal_sleep_pattern0.30448102
119MP0010329_abnormal_lipoprotein_level0.29249457
120MP0000465_gastrointestinal_hemorrhage0.28073430
121MP0000537_abnormal_urethra_morphology0.26566075
122MP0010352_gastrointestinal_tract_polyps0.26415697
123MP0005248_abnormal_Harderian_gland0.26213096
124MP0002697_abnormal_eye_size0.25509201
125MP0009840_abnormal_foam_cell0.24652666
126MP0003763_abnormal_thymus_physiology0.21705858
127MP0001879_abnormal_lymphatic_vessel0.20335507
128MP0003011_delayed_dark_adaptation0.19013682
129MP0003950_abnormal_plasma_membrane0.18310928
130MP0000432_abnormal_head_morphology0.18307957
131MP0004019_abnormal_vitamin_homeostasis0.17768229
132MP0003329_amyloid_beta_deposits0.17421546
133MP0004742_abnormal_vestibular_system0.16871807
134MP0003448_altered_tumor_morphology0.15949449
135MP0003935_abnormal_craniofacial_develop0.15793242
136MP0000751_myopathy0.13770584
137MP0005666_abnormal_adipose_tissue0.13390903
138MP0006054_spinal_hemorrhage0.12852164
139MP0003638_abnormal_response/metabolism_0.12051722
140MP0005375_adipose_tissue_phenotype0.11980142
141MP0003300_gastrointestinal_ulcer0.11567909
142MP0004858_abnormal_nervous_system0.10894693
143MP0000462_abnormal_digestive_system0.09339362
144MP0002233_abnormal_nose_morphology0.09091475
145MP0005193_abnormal_anterior_eye0.08403441
146MP0001188_hyperpigmentation0.08181513
147MP0005076_abnormal_cell_differentiation0.07953970
148MP0000750_abnormal_muscle_regeneration0.07804241
149MP0000538_abnormal_urinary_bladder0.07611170
150MP0000747_muscle_weakness0.07587291
151MP0008569_lethality_at_weaning0.07480166
152MP0005508_abnormal_skeleton_morphology0.07059384
153MP0000013_abnormal_adipose_tissue0.07041837
154MP0000604_amyloidosis0.06566913
155MP0003075_altered_response_to0.06485576
156MP0001958_emphysema0.06180073
157MP0002006_tumorigenesis0.06067189
158MP0002166_altered_tumor_susceptibility0.05632893
159MP0000516_abnormal_urinary_system0.05507205

Predicted human phenotypes

RankGene SetZ-score
1Pili torti (HP:0003777)9.12170807
2Nail dystrophy (HP:0008404)7.40529854
3Abnormality of nail color (HP:0100643)5.73744306
4Abnormal hair laboratory examination (HP:0003328)5.72519137
5Absent eyebrow (HP:0002223)5.52085701
6Fragile nails (HP:0001808)5.45310809
7Fine hair (HP:0002213)5.35123804
8Absent hair (HP:0002298)4.84177343
9Chronic otitis media (HP:0000389)4.66074539
10Onycholysis (HP:0001806)4.64820413
11Palmoplantar hyperkeratosis (HP:0000972)4.61230703
12Alopecia of scalp (HP:0002293)4.59509876
13Increased IgE level (HP:0003212)4.46321564
14Palmar hyperkeratosis (HP:0010765)4.33544511
15Plantar hyperkeratosis (HP:0007556)4.18723451
16Right ventricular cardiomyopathy (HP:0011663)4.09342612
17Thick nail (HP:0001805)4.08350996
18Follicular hyperkeratosis (HP:0007502)4.02069364
19Abnormality of the axillary hair (HP:0100134)3.93572082
20Abnormality of secondary sexual hair (HP:0009888)3.93572082
21Sparse eyelashes (HP:0000653)3.50567590
22Erythema (HP:0010783)3.46735923
23Amelogenesis imperfecta (HP:0000705)3.17497415
24Abnormality of the frontal sinuses (HP:0002687)3.14872246
25Parakeratosis (HP:0001036)3.11179010
26Oral leukoplakia (HP:0002745)3.11094869
27Erythroderma (HP:0001019)2.98905382
28Congenital, generalized hypertrichosis (HP:0004540)2.90859963
29Milia (HP:0001056)2.89120240
30Curly hair (HP:0002212)2.74894450
31Dry hair (HP:0011359)2.72964830
32Abnormality of the proximal phalanges of the hand (HP:0009834)2.70042190
33Aplasia cutis congenita (HP:0001057)2.64591356
34Congenital ichthyosiform erythroderma (HP:0007431)2.58360690
35Bilateral microphthalmos (HP:0007633)2.58229961
36Morphological abnormality of the middle ear (HP:0008609)2.57782257
37Intention tremor (HP:0002080)2.57500515
38Natal tooth (HP:0000695)2.56223713
39Ridged nail (HP:0001807)2.49417255
40Neck muscle weakness (HP:0000467)2.46131023
41Abnormality of the middle phalanges of the toes (HP:0010183)2.45231376
42Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.40704253
43Torticollis (HP:0000473)2.38033526
44Advanced eruption of teeth (HP:0006288)2.34972049
45Abnormal respiratory motile cilium morphology (HP:0005938)2.33714614
46Abnormal respiratory epithelium morphology (HP:0012253)2.33714614
47Abnormal blistering of the skin (HP:0008066)2.23631407
48Abnormality of the nasal septum (HP:0000419)2.18881510
49Furrowed tongue (HP:0000221)2.17913019
50Corneal erosion (HP:0200020)2.10361898
51Aplasia/Hypoplasia of the sternum (HP:0006714)2.03332132
52Clumsiness (HP:0002312)2.03173240
53Hypohidrosis (HP:0000966)2.03149351
54Craniofacial dystonia (HP:0012179)2.01643061
55Hypotrichosis (HP:0001006)15.0369999
56Abnormality of hair growth rate (HP:0011363)11.4360011
57Slow-growing hair (HP:0002217)11.4360011
58Woolly hair (HP:0002224)11.2073540
59Brittle hair (HP:0002299)10.7350717
60Chronic sinusitis (HP:0011109)1.96877082
61Palmoplantar keratoderma (HP:0000982)1.96693409
62Aplasia/Hypoplasia of the hallux (HP:0008362)1.95719215
63Aplasia/Hypoplasia of the spleen (HP:0010451)1.94740965
64Short hallux (HP:0010109)1.94543641
65Humeroradial synostosis (HP:0003041)1.94096418
66Synostosis involving the elbow (HP:0003938)1.94096418
67Ventricular tachycardia (HP:0004756)1.92938217
68Pruritus (HP:0000989)1.91633319
69Asplenia (HP:0001746)1.89236067
70Difficulty walking (HP:0002355)1.87246812
71Abnormality of the pupil (HP:0000615)1.87136032
72Abnormality of the costochondral junction (HP:0000919)1.85403401
73Abnormality of the parietal bone (HP:0002696)1.84471406
74Focal dystonia (HP:0004373)1.84299898
75Concave nail (HP:0001598)1.83480294
76Abnormality of dental color (HP:0011073)1.83278385
77Gonadotropin excess (HP:0000837)1.81767487
78Abnormality of the dental root (HP:0006486)1.79112592
79Taurodontia (HP:0000679)1.79112592
80Abnormality of permanent molar morphology (HP:0011071)1.79112592
81Abnormality of molar morphology (HP:0011070)1.76223003
82Abnormality of molar (HP:0011077)1.76223003
83Ventricular fibrillation (HP:0001663)1.74788564
84Nephronophthisis (HP:0000090)1.71311981
85Widely patent fontanelles and sutures (HP:0004492)1.67498636
86Conjunctival hamartoma (HP:0100780)1.67437564
87Carpal bone hypoplasia (HP:0001498)1.64649423
88Recurrent corneal erosions (HP:0000495)1.62583624
89Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.62346139
90Hyporeflexia of lower limbs (HP:0002600)1.62223495
91Absent eyelashes (HP:0000561)1.59379529
92Stomach cancer (HP:0012126)1.58168739
93Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.57766892
94Abnormality of alanine metabolism (HP:0010916)1.57766892
95Hyperalaninemia (HP:0003348)1.57766892
96Abnormality of the dental pulp (HP:0006479)1.57532959
97Amniotic constriction ring (HP:0009775)1.56080376
98Abnormality of placental membranes (HP:0011409)1.56080376
99Unilateral renal agenesis (HP:0000122)1.54158122
100Long nose (HP:0003189)1.52450165
101Symphalangism affecting the phalanges of the hand (HP:0009773)1.51985941
102Attenuation of retinal blood vessels (HP:0007843)1.51975889
103Chorioretinal atrophy (HP:0000533)1.51061574
104Short 1st metacarpal (HP:0010034)1.50247236
105Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.50247236
106Methylmalonic acidemia (HP:0002912)1.50210444
107Hamartoma of the eye (HP:0010568)1.50004456
108Recurrent sinusitis (HP:0011108)1.49918208
109Abnormality of the aortic arch (HP:0012303)1.49895615
110Absent phalangeal crease (HP:0006109)1.48486765
111Enlarged penis (HP:0000040)1.47901033
112Sudden death (HP:0001699)1.47649732
113Blepharitis (HP:0000498)1.47293668
114Abnormality of the neuromuscular junction (HP:0003398)1.46558928
115Fatigable weakness (HP:0003473)1.46558928
116Heterogeneous (HP:0001425)1.46359369
117Fused cervical vertebrae (HP:0002949)1.45344151
118Distal lower limb muscle weakness (HP:0009053)1.44977645
119Urticaria (HP:0001025)1.44915330
120Abnormality of the phalanges of the 5th finger (HP:0004213)1.44238968
121Multifactorial inheritance (HP:0001426)1.44119107
122Abnormality of the columella (HP:0009929)1.43950400
123Abnormality of the prostate (HP:0008775)1.43680408
124Thyroid-stimulating hormone excess (HP:0002925)1.42927006
125Abnormality of the distal phalanges of the toes (HP:0010182)1.42575471
126Acanthosis nigricans (HP:0000956)1.41386624
127Pancreatic cysts (HP:0001737)1.41045831
128Lip pit (HP:0100267)1.40405851
129Xerostomia (HP:0000217)1.39476831
130Autoamputation (HP:0001218)1.39166615
131Radial bowing (HP:0002986)1.37036917
132Abnormality of the renal medulla (HP:0100957)1.35815855
133Abolished electroretinogram (ERG) (HP:0000550)1.35488514
134Hyperventilation (HP:0002883)1.35386080
135Carious teeth (HP:0000670)1.32763389
136Gangrene (HP:0100758)1.32415766
137Keratoconjunctivitis sicca (HP:0001097)1.32257422
138Round ear (HP:0100830)1.31842313
139Achilles tendon contracture (HP:0001771)1.31187266
140Craniofacial hyperostosis (HP:0004493)1.31072097
141Ectropion (HP:0000656)1.29229920
142Hypergammaglobulinemia (HP:0010702)1.26246495
143Anonychia (HP:0001798)1.25405295
144Sparse scalp hair (HP:0002209)1.24178875
145Abnormality of the Achilles tendon (HP:0005109)1.23368685
146Variable expressivity (HP:0003828)1.23060859
147Abnormality of the fingernails (HP:0001231)1.19937121
148Type 1 muscle fiber predominance (HP:0003803)1.19243923
149Keratoconjunctivitis (HP:0001096)1.18295298
150Widely spaced teeth (HP:0000687)1.17795432
151Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.15906472
152Selective tooth agenesis (HP:0001592)1.14694555
153Neonatal onset (HP:0003623)1.14214713
154Bronchomalacia (HP:0002780)1.11756213
155Lack of skin elasticity (HP:0100679)1.08706417
156Atrophic scars (HP:0001075)1.08411836
157Increased connective tissue (HP:0009025)1.06092544

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.91349357
2EPHA24.64153530
3MAPKAPK34.13965298
4INSRR4.04886178
5FER3.93872244
6TLK13.68093661
7FRK3.53982619
8ERN13.53149341
9MAP3K63.52509838
10TAOK13.36468870
11EPHB23.04793403
12KIT2.91782527
13MAP3K32.70055671
14MAP4K22.65614549
15GRK12.56562539
16TAOK32.49015646
17PLK42.42279545
18LATS12.41182190
19TEC2.40886431
20PIK3CG2.39513539
21MKNK12.36284254
22RIPK42.30449555
23MAP3K22.25892589
24TRIB32.25357595
25PINK12.24860544
26MAPKAPK52.11453828
27ZAK2.10820273
28BCKDK2.09349098
29RPS6KB22.06366205
30ITK1.98327850
31MAP3K111.94219852
32EEF2K1.93307240
33TTN1.92248024
34ADRBK21.91340317
35DAPK21.78908381
36FLT31.78901020
37LATS21.69248052
38MAP2K61.67490467
39NME11.61500620
40MAP4K11.56057675
41EPHB11.51201645
42TNK21.48772953
43OXSR11.44582027
44DAPK11.41290120
45KSR21.38943734
46TIE11.38222875
47RPS6KA51.32263542
48BCR1.28759971
49CSF1R1.26974229
50MAP3K11.20145816
51FGFR11.17552894
52FGFR21.14022739
53MST1R1.14006504
54FGFR41.12703331
55PBK1.11748575
56IKBKB1.10116770
57MAP3K71.08503565
58BMX1.08416260
59FES1.08177493
60LRRK21.08143172
61BLK1.05172751
62MAP2K31.04834054
63PDK21.04709101
64ADRBK11.04299266
65STK391.02447166
66CDK191.01788950
67MAPKAPK21.00688617
68EIF2AK30.99658345
69MAP3K130.98665568
70CDK60.97590202
71PDGFRA0.97195622
72KDR0.96459906
73SYK0.96016057
74STK160.94924597
75RIPK10.93934139
76PLK20.89191562
77BTK0.87496053
78PAK30.87212737
79FGFR30.86500469
80PTK60.86391090
81TXK0.85462736
82ABL10.84479207
83BMPR20.83849707
84MAP2K40.83033876
85DYRK1B0.82757530
86OBSCN0.80081484
87MAP2K10.79709222
88RPS6KA60.79293727
89PKN20.79067133
90PRKCQ0.73850384
91SIK10.72641071
92PAK60.72484949
93NUAK10.71767669
94MAP3K90.71370485
95PAK40.71210654
96LYN0.70638133
97PRKD10.68975290
98STK38L0.68589338
99STK380.68101023
100NTRK20.67833088
101IKBKE0.67345923
102PTK20.66709472
103PRKCE0.66281508
104TRPM70.65094078
105TYRO30.64805166
106GRK70.64662822
107TBK10.64463365
108ERBB40.63740506
109PIM20.59984156
110MAPK120.59876608
111RPS6KL10.58128535
112RPS6KC10.58128535
113MAPK130.57114770
114MAPK30.56930904
115DDR20.56758404
116MET0.55751865
117PRKCH0.53182982
118RPS6KA40.52013324
119RPS6KA20.51991214
120WNK40.50046515
121CSNK1E0.49507335
122RPS6KA10.49271097
123CHUK0.49131244
124GSK3A0.48839145
125PIK3CA0.48425514
126IGF1R0.47916712
127TESK10.46371232
128TGFBR10.45990381
129MAPK70.45704139
130CDK30.45306820
131PAK20.45036596
132ILK0.44515938
133ERBB20.43729638
134CSNK1A1L0.42405799
135PHKG10.42210388
136PHKG20.42210388
137ALK0.41982802
138MARK10.41536360
139JAK10.41443900
140CSNK1G30.40440777
141GRK50.39875427
142NEK10.39766301
143SGK20.39645335
144CAMKK10.39522559
145PRKCI0.38889197
146MAP3K100.38830573
147IRAK10.38571632
148RPS6KB10.37328379
149MAP3K50.37311986
150MYLK0.37181409
151RET0.37079400
152NTRK30.36288626
153ERBB30.35155127
154JAK20.35026988
155PDK10.34714254
156SIK20.34652561
157LCK0.33470291
158FYN0.33073379
159CSNK1G10.32885292
160CAMK2A0.32407314
161GRK60.32133095
162PRKCA0.31089831
163HCK0.30856942
164MST40.30727148
165MAPK40.29525701
166MAP2K20.29403455
167CSNK1A10.28631740
168TYK20.28557155
169EPHA30.28335765
170PRKACA0.27711869
171MARK20.27549848
172PKN10.26556819
173PRKCG0.26393330
174ROCK20.26146636
175TGFBR20.25120175
176MAPK10.20515753
177PRKG20.19511583
178CSNK2A10.19419499

Predicted pathways (KEGG)

RankGene SetZ-score
1Linoleic acid metabolism_Homo sapiens_hsa005914.81054962
2alpha-Linolenic acid metabolism_Homo sapiens_hsa005924.79948623
3Asthma_Homo sapiens_hsa053103.93941263
4Fat digestion and absorption_Homo sapiens_hsa049753.19056136
5Allograft rejection_Homo sapiens_hsa053303.03738070
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.88492058
7Fatty acid elongation_Homo sapiens_hsa000622.88129393
8Autoimmune thyroid disease_Homo sapiens_hsa053202.79897774
9Graft-versus-host disease_Homo sapiens_hsa053322.75424133
10Type I diabetes mellitus_Homo sapiens_hsa049402.67223181
11Ether lipid metabolism_Homo sapiens_hsa005652.46593969
12Basal cell carcinoma_Homo sapiens_hsa052172.17207390
13Vitamin digestion and absorption_Homo sapiens_hsa049772.16384073
14Glycerolipid metabolism_Homo sapiens_hsa005612.15305480
15Phenylalanine metabolism_Homo sapiens_hsa003601.92026704
16Arachidonic acid metabolism_Homo sapiens_hsa005901.91014969
17Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.85022704
18Ovarian steroidogenesis_Homo sapiens_hsa049131.80251966
19VEGF signaling pathway_Homo sapiens_hsa043701.76784163
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.75662526
21Fatty acid biosynthesis_Homo sapiens_hsa000611.66618841
22Melanogenesis_Homo sapiens_hsa049161.61624134
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.58785655
24Axon guidance_Homo sapiens_hsa043601.56777523
25Retinol metabolism_Homo sapiens_hsa008301.51474768
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.45109737
27Hedgehog signaling pathway_Homo sapiens_hsa043401.38585637
28Histidine metabolism_Homo sapiens_hsa003401.37947579
29Glioma_Homo sapiens_hsa052141.36556330
30Antigen processing and presentation_Homo sapiens_hsa046121.34495498
31GnRH signaling pathway_Homo sapiens_hsa049121.31880270
32Bladder cancer_Homo sapiens_hsa052191.31506298
33Vascular smooth muscle contraction_Homo sapiens_hsa042701.30146632
34Proteoglycans in cancer_Homo sapiens_hsa052051.28169490
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.27497600
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.26077997
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.23850497
38Rheumatoid arthritis_Homo sapiens_hsa053231.23101169
39Hippo signaling pathway_Homo sapiens_hsa043901.22278382
40Caffeine metabolism_Homo sapiens_hsa002321.21910999
41Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.19068613
42Acute myeloid leukemia_Homo sapiens_hsa052211.18975578
43Mineral absorption_Homo sapiens_hsa049781.16232389
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.16072525
45Leishmaniasis_Homo sapiens_hsa051401.14583715
46Peroxisome_Homo sapiens_hsa041461.14261778
47Thyroid cancer_Homo sapiens_hsa052161.13411860
48Pancreatic secretion_Homo sapiens_hsa049721.13193667
49Tight junction_Homo sapiens_hsa045301.10844952
50Circadian entrainment_Homo sapiens_hsa047131.07214246
51Long-term potentiation_Homo sapiens_hsa047201.06431640
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.03638600
53Dorso-ventral axis formation_Homo sapiens_hsa043201.03055125
54Tyrosine metabolism_Homo sapiens_hsa003500.99909028
55Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99261730
56PPAR signaling pathway_Homo sapiens_hsa033200.99002812
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.96745917
58Propanoate metabolism_Homo sapiens_hsa006400.96435508
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.93810043
60Taste transduction_Homo sapiens_hsa047420.93306695
61Pertussis_Homo sapiens_hsa051330.91733363
62ECM-receptor interaction_Homo sapiens_hsa045120.89901950
63Systemic lupus erythematosus_Homo sapiens_hsa053220.89352741
64Long-term depression_Homo sapiens_hsa047300.88866230
65Non-small cell lung cancer_Homo sapiens_hsa052230.87066447
66Steroid biosynthesis_Homo sapiens_hsa001000.86972460
67Estrogen signaling pathway_Homo sapiens_hsa049150.86152658
68Phototransduction_Homo sapiens_hsa047440.84559640
69Glycerophospholipid metabolism_Homo sapiens_hsa005640.84094344
70RNA degradation_Homo sapiens_hsa030180.83378039
71Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82238157
72Tryptophan metabolism_Homo sapiens_hsa003800.81840219
73Ras signaling pathway_Homo sapiens_hsa040140.81694092
74Leukocyte transendothelial migration_Homo sapiens_hsa046700.78997833
75Endometrial cancer_Homo sapiens_hsa052130.77793015
76Adherens junction_Homo sapiens_hsa045200.77590099
77Viral myocarditis_Homo sapiens_hsa054160.77152748
78Staphylococcus aureus infection_Homo sapiens_hsa051500.76595522
79Wnt signaling pathway_Homo sapiens_hsa043100.75980819
80Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.75149186
81Nitrogen metabolism_Homo sapiens_hsa009100.75047956
82Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.74901672
83Gastric acid secretion_Homo sapiens_hsa049710.74630043
84Amoebiasis_Homo sapiens_hsa051460.74052077
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.73864276
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.73776173
87beta-Alanine metabolism_Homo sapiens_hsa004100.73499691
88ABC transporters_Homo sapiens_hsa020100.70513517
89Renin secretion_Homo sapiens_hsa049240.69069512
90Homologous recombination_Homo sapiens_hsa034400.67917917
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65752763
92Serotonergic synapse_Homo sapiens_hsa047260.65320066
93Gap junction_Homo sapiens_hsa045400.65281687
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.64198389
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.62578714
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61382558
97Rap1 signaling pathway_Homo sapiens_hsa040150.60416659
98Oxytocin signaling pathway_Homo sapiens_hsa049210.60371861
99Salivary secretion_Homo sapiens_hsa049700.59427948
100Renal cell carcinoma_Homo sapiens_hsa052110.59357143
101MicroRNAs in cancer_Homo sapiens_hsa052060.58403413
102Hematopoietic cell lineage_Homo sapiens_hsa046400.56420262
103Hepatitis C_Homo sapiens_hsa051600.55647242
104Fatty acid metabolism_Homo sapiens_hsa012120.53188803
105RNA polymerase_Homo sapiens_hsa030200.52947393
106Salmonella infection_Homo sapiens_hsa051320.52867664
107p53 signaling pathway_Homo sapiens_hsa041150.52604193
108Sphingolipid metabolism_Homo sapiens_hsa006000.50853940
109ErbB signaling pathway_Homo sapiens_hsa040120.50557808
110Central carbon metabolism in cancer_Homo sapiens_hsa052300.49957505
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49743434
112Insulin resistance_Homo sapiens_hsa049310.49147068
113Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48621801
114Nicotine addiction_Homo sapiens_hsa050330.48335343
115Protein digestion and absorption_Homo sapiens_hsa049740.46519684
116Ribosome_Homo sapiens_hsa030100.46397354
117Platelet activation_Homo sapiens_hsa046110.46321246
118Chemical carcinogenesis_Homo sapiens_hsa052040.46037254
119Olfactory transduction_Homo sapiens_hsa047400.45876214
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45796777
121Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.44529327
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44498286
123Prolactin signaling pathway_Homo sapiens_hsa049170.43452968
124Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42967696
125Choline metabolism in cancer_Homo sapiens_hsa052310.42747776
126Focal adhesion_Homo sapiens_hsa045100.41883392
127Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40816049
128Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39150067
129Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39087386
130TGF-beta signaling pathway_Homo sapiens_hsa043500.38914621
131Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38453966
132Dopaminergic synapse_Homo sapiens_hsa047280.38027757
133Butanoate metabolism_Homo sapiens_hsa006500.38003898
134Melanoma_Homo sapiens_hsa052180.37554270
135Prion diseases_Homo sapiens_hsa050200.37316535
136Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.37293179
137Calcium signaling pathway_Homo sapiens_hsa040200.36824597
138Tuberculosis_Homo sapiens_hsa051520.35653359
139Notch signaling pathway_Homo sapiens_hsa043300.35493457
140Fatty acid degradation_Homo sapiens_hsa000710.35245257
141Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35185051
142Chronic myeloid leukemia_Homo sapiens_hsa052200.34566191
143Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.33748015
144Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.27526266
145Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25788697
146Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23605129
147Fanconi anemia pathway_Homo sapiens_hsa034600.22830641
148Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.22214056
149Purine metabolism_Homo sapiens_hsa002300.22126995
150Pyruvate metabolism_Homo sapiens_hsa006200.20159331
151NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20134220
152Type II diabetes mellitus_Homo sapiens_hsa049300.18796138
153Toxoplasmosis_Homo sapiens_hsa051450.18469717
154Metabolic pathways_Homo sapiens_hsa011000.18368184
155Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.16360833
156Regulation of autophagy_Homo sapiens_hsa041400.16186268
157Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.15876462
158Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.13385632

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