KRTAP5-2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intermediate filament organization (GO:0045109)9.59200052
2establishment of skin barrier (GO:0061436)8.89487048
3adhesion of symbiont to host cell (GO:0044650)8.53510843
4virion attachment to host cell (GO:0019062)8.53510843
5cell wall macromolecule catabolic process (GO:0016998)8.35715935
6cell wall macromolecule metabolic process (GO:0044036)8.35715935
7peptide cross-linking (GO:0018149)7.97508631
8regulation of water loss via skin (GO:0033561)7.71176185
9adhesion of symbiont to host (GO:0044406)7.11429277
10citrulline biosynthetic process (GO:0019240)7.01564054
11hair follicle morphogenesis (GO:0031069)6.51519697
12synaptic vesicle maturation (GO:0016188)6.47445513
13epidermis development (GO:0008544)6.35579407
14keratinocyte differentiation (GO:0030216)6.32022698
15regulation of short-term neuronal synaptic plasticity (GO:0048172)6.31412102
16skin morphogenesis (GO:0043589)5.80676593
17bundle of His cell to Purkinje myocyte communication (GO:0086069)5.75786685
18intermediate filament cytoskeleton organization (GO:0045104)5.55711143
19glutamate secretion (GO:0014047)5.36834996
20intermediate filament-based process (GO:0045103)5.36289981
21multicellular organismal water homeostasis (GO:0050891)5.26645378
22peptidyl-arginine modification (GO:0018195)5.09860782
23synaptic vesicle docking involved in exocytosis (GO:0016081)5.09516665
24hair cycle process (GO:0022405)5.07930910
25molting cycle process (GO:0022404)5.07930910
26synaptic vesicle exocytosis (GO:0016079)4.98807635
27hemidesmosome assembly (GO:0031581)4.98292574
28epidermal cell differentiation (GO:0009913)4.88340513
29pyrimidine nucleobase catabolic process (GO:0006208)4.82923031
30neuron cell-cell adhesion (GO:0007158)4.64984064
31vocalization behavior (GO:0071625)4.62380667
32regulation of synaptic vesicle exocytosis (GO:2000300)4.61022002
33regulation of synaptic vesicle transport (GO:1902803)4.53911923
34citrulline metabolic process (GO:0000052)4.44043696
35fatty acid elongation (GO:0030497)4.43477772
36tooth mineralization (GO:0034505)4.39863895
37postsynaptic membrane organization (GO:0001941)4.38051760
38positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.36240873
39positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.34115987
40neurotransmitter secretion (GO:0007269)4.32798250
41water homeostasis (GO:0030104)4.32555423
42locomotory exploration behavior (GO:0035641)4.31997380
43ionotropic glutamate receptor signaling pathway (GO:0035235)4.21063019
44hair follicle development (GO:0001942)4.19448548
45positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.17682458
46positive regulation of hair cycle (GO:0042635)4.05486297
47positive regulation of hair follicle development (GO:0051798)4.05486297
48dendritic spine morphogenesis (GO:0060997)3.98998763
49layer formation in cerebral cortex (GO:0021819)3.87774005
50nucleobase catabolic process (GO:0046113)3.85607018
51keratinocyte development (GO:0003334)3.85157330
52neuronal ion channel clustering (GO:0045161)3.84825975
53protein localization to synapse (GO:0035418)3.82152494
54negative regulation of erythrocyte differentiation (GO:0045647)3.81407092
55regulation of hair follicle development (GO:0051797)3.76241308
56gamma-aminobutyric acid transport (GO:0015812)3.76191636
57regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.72716216
58presynaptic membrane assembly (GO:0097105)3.72286846
59positive regulation of meiotic cell cycle (GO:0051446)3.71701872
60sodium ion export (GO:0071436)3.71035788
61epithelial cell differentiation involved in prostate gland development (GO:0060742)3.69300369
62cell migration in hindbrain (GO:0021535)3.64642327
63axonal fasciculation (GO:0007413)3.63306155
64bone trabecula formation (GO:0060346)3.59561325
65gap junction assembly (GO:0016264)3.58454712
66synaptic transmission, glutamatergic (GO:0035249)3.58382914
67exploration behavior (GO:0035640)3.53386451
68neuromuscular synaptic transmission (GO:0007274)3.53084471
69regulation of neuronal synaptic plasticity (GO:0048168)3.52630485
70membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.52541136
71negative regulation of microtubule polymerization (GO:0031115)3.47507643
72negative regulation of synaptic transmission, GABAergic (GO:0032229)3.43342251
73presynaptic membrane organization (GO:0097090)3.42611875
74cellular potassium ion homeostasis (GO:0030007)3.42029570
75dendritic spine organization (GO:0097061)3.40199744
76neurofilament cytoskeleton organization (GO:0060052)3.38998861
77cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.36556310
78neuron recognition (GO:0008038)3.33402417
79negative regulation of keratinocyte proliferation (GO:0010839)3.30210648
80glutamate receptor signaling pathway (GO:0007215)3.28429046
81neurotransmitter transport (GO:0006836)3.27729351
82neurotransmitter-gated ion channel clustering (GO:0072578)3.26326518
83cell communication by electrical coupling (GO:0010644)3.23238911
84regulation of hair cycle (GO:0042634)3.22761350
85positive regulation of synapse maturation (GO:0090129)3.20651472
86establishment of mitochondrion localization (GO:0051654)3.19633582
87regulation of neurotransmitter levels (GO:0001505)3.17034236
88regulation of glutamate receptor signaling pathway (GO:1900449)3.16793287
89epithelium development (GO:0060429)3.16720198
90regulation of long-term neuronal synaptic plasticity (GO:0048169)3.16232184
91adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.14379988
92synapse assembly (GO:0007416)3.13026227
93regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.10154537
94neuron-neuron synaptic transmission (GO:0007270)3.08966745
95regulation of mesenchymal cell apoptotic process (GO:2001053)3.08586423
96transmission of nerve impulse (GO:0019226)3.07185820
97organelle transport along microtubule (GO:0072384)3.04313630
98myotube differentiation (GO:0014902)3.03919904
99creatine metabolic process (GO:0006600)3.03038594
100regulation of neurotransmitter secretion (GO:0046928)3.01462636
101regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.00775656
102hair cycle (GO:0042633)25.7265254
103molting cycle (GO:0042303)25.7265254
104gamma-aminobutyric acid signaling pathway (GO:0007214)2.96474046
105cerebellar Purkinje cell differentiation (GO:0021702)2.95665778
106regulation of vesicle fusion (GO:0031338)2.94809281
107positive regulation of dendritic spine morphogenesis (GO:0061003)2.94646996
108dendrite morphogenesis (GO:0048813)2.90774813
109vesicle transport along microtubule (GO:0047496)2.89868776
110epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.89520648
111lymph vessel development (GO:0001945)2.89292568
112establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.87839751
113mitochondrion transport along microtubule (GO:0047497)2.87839751
114regulation of excitatory postsynaptic membrane potential (GO:0060079)2.85389593
115membrane depolarization during action potential (GO:0086010)2.85247844
116regulation of cardioblast differentiation (GO:0051890)2.84700670
117positive regulation of membrane potential (GO:0045838)2.82411185
118synaptic vesicle endocytosis (GO:0048488)2.82008723
119regulation of synapse structural plasticity (GO:0051823)2.81947826
120atrioventricular valve morphogenesis (GO:0003181)2.81748713
121ectoderm development (GO:0007398)2.79914980
122respiratory system process (GO:0003016)2.79155856
123regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.79114609
124regulation of postsynaptic membrane potential (GO:0060078)2.77126788
125positive regulation of epidermis development (GO:0045684)2.75641402
126neuromuscular process controlling balance (GO:0050885)2.75581690
127cerebellar granule cell differentiation (GO:0021707)2.74053985
128skin development (GO:0043588)2.73493456
129keratinocyte proliferation (GO:0043616)2.71432473
130regulation of synaptic plasticity (GO:0048167)2.71081379
131regulation of keratinocyte differentiation (GO:0045616)2.71039251
132behavioral response to cocaine (GO:0048148)2.70213405
133long-term memory (GO:0007616)2.69915728
134regulation of autophagic vacuole assembly (GO:2000785)2.69043469
135synapse organization (GO:0050808)2.67023963
136cell surface receptor signaling pathway involved in heart development (GO:0061311)2.64493372
137ventricular cardiac muscle cell action potential (GO:0086005)2.64202340
138very long-chain fatty acid metabolic process (GO:0000038)2.63263299
139positive regulation of synapse assembly (GO:0051965)2.63114751
140signal release (GO:0023061)2.62989366
141regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.62681124
142regulation of dendritic spine morphogenesis (GO:0061001)2.61898416
143activation of protein kinase A activity (GO:0034199)2.60427990
144membrane depolarization (GO:0051899)2.59152130
145regulation of synapse maturation (GO:0090128)2.58620919
146regulation of voltage-gated calcium channel activity (GO:1901385)2.56944308
147dopamine receptor signaling pathway (GO:0007212)2.56925852
148regulation of neurotransmitter transport (GO:0051588)2.55270259
149negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.54361508
150axon extension (GO:0048675)2.53927355
151negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.51758256
152establishment of vesicle localization (GO:0051650)2.50914660
153long-chain fatty acid biosynthetic process (GO:0042759)2.50223102
154negative regulation of establishment of protein localization to plasma membrane (GO:0090005)2.48654371
155embryonic camera-type eye development (GO:0031076)2.46507613
156negative regulation of cell fate specification (GO:0009996)2.46343526
157valine metabolic process (GO:0006573)2.45162184
158cranial suture morphogenesis (GO:0060363)2.42903634
159positive regulation of meiosis (GO:0045836)2.39886318
160regulation of epidermis development (GO:0045682)2.38101332
161cell communication involved in cardiac conduction (GO:0086065)2.35526688
162long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.34896297
163planar cell polarity pathway involved in neural tube closure (GO:0090179)2.29711691
164outflow tract septum morphogenesis (GO:0003148)2.25501690
165phosphatidylinositol acyl-chain remodeling (GO:0036149)2.24054002
166fatty-acyl-CoA biosynthetic process (GO:0046949)2.22321738
167wound healing, spreading of epidermal cells (GO:0035313)2.21504629
168long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.19808438
169regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.19123207
170cytoskeletal anchoring at plasma membrane (GO:0007016)2.17990151
171non-canonical Wnt signaling pathway (GO:0035567)2.17793612
172regulation of secondary heart field cardioblast proliferation (GO:0003266)2.17175262
173regulation of cardioblast proliferation (GO:0003264)2.17175262
174regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.16844192
175regulation of transforming growth factor beta2 production (GO:0032909)2.13865117
176epithelial cell-cell adhesion (GO:0090136)2.13670125
177coronary vasculature morphogenesis (GO:0060977)2.12453365
178cardiac epithelial to mesenchymal transition (GO:0060317)2.11859937
179skeletal muscle fiber development (GO:0048741)2.08249825
180positive regulation of natural killer cell differentiation (GO:0032825)2.07735030
181outer ear morphogenesis (GO:0042473)2.04678774
182regulation of heart rate by cardiac conduction (GO:0086091)2.04310652
183negative regulation of epidermis development (GO:0045683)2.04289491
184regulation of epidermal cell differentiation (GO:0045604)2.00005574
185keratinization (GO:0031424)12.7085356
186desmosome organization (GO:0002934)11.0032175
187establishment of tissue polarity (GO:0007164)1.99824837
188establishment of planar polarity (GO:0001736)1.99824837
189phosphatidylserine acyl-chain remodeling (GO:0036150)1.99197608
190ephrin receptor signaling pathway (GO:0048013)1.97157302
191peptidyl-arginine omega-N-methylation (GO:0035247)1.97088966
192negative regulation of protein localization to plasma membrane (GO:1903077)1.95009831
193phosphatidylcholine acyl-chain remodeling (GO:0036151)1.94880087
194positive regulation of monocyte chemotaxis (GO:0090026)1.94074670

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.19735782
2CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human4.72320658
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse4.00542270
4EZH2_22144423_ChIP-Seq_EOC_Human3.59623395
5ZFP322A_24550733_ChIP-Seq_MESCs_Mouse3.40837056
6P63_26484246_Chip-Seq_KERATINOCYTES_Human3.09819497
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.96830468
8PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.77374049
9EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.61080897
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.50436625
11GBX2_23144817_ChIP-Seq_PC3_Human2.47430616
12REST_21632747_ChIP-Seq_MESCs_Mouse2.45346555
13DROSHA_22980978_ChIP-Seq_HELA_Human2.31312393
14REST_18959480_ChIP-ChIP_MESCs_Mouse2.23974135
15RARB_27405468_Chip-Seq_BRAIN_Mouse2.15565220
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.11535800
17ESR1_20079471_ChIP-ChIP_T-47D_Human2.04528717
18SOX9_24532713_ChIP-Seq_HFSC_Mouse2.02343043
19TP63_17297297_ChIP-ChIP_HaCaT_Human11.2233084
20ZFP281_18757296_ChIP-ChIP_E14_Mouse1.89166625
21VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.84829957
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64694831
23* CBX2_27304074_Chip-Seq_ESCs_Mouse1.61829612
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.59311266
25RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.58109331
26IGF1R_20145208_ChIP-Seq_DFB_Human1.57168897
27CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.55256759
28GATA1_22025678_ChIP-Seq_K562_Human1.54606439
29SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49613059
30ESR1_21235772_ChIP-Seq_MCF-7_Human1.49398138
31RNF2_27304074_Chip-Seq_NSC_Mouse1.48215628
32* CTCF_20526341_ChIP-Seq_ESCs_Human1.45830216
33JARID2_20075857_ChIP-Seq_MESCs_Mouse1.45688929
34ESR2_21235772_ChIP-Seq_MCF-7_Human1.43589942
35KDM2B_26808549_Chip-Seq_K562_Human1.42959421
36EGR1_19032775_ChIP-ChIP_M12_Human1.42939047
37TP53_20018659_ChIP-ChIP_R1E_Mouse1.42519880
38NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.42000117
39ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36711608
40CTCF_27219007_Chip-Seq_Bcells_Human1.36156462
41TP63_23658742_ChIP-Seq_EP156T_Human1.34920992
42FOXO3_23340844_ChIP-Seq_DLD1_Human1.34869350
43AR_21572438_ChIP-Seq_LNCaP_Human1.34761118
44SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.32921614
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32382286
46TRIM28_21343339_ChIP-Seq_HEK293_Human1.31803396
47WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.31479410
48CTBP2_25329375_ChIP-Seq_LNCAP_Human1.31131402
49ERG_20517297_ChIP-Seq_VCAP_Human1.30959736
50TP63_22573176_ChIP-Seq_HFKS_Human1.30909325
51RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.29115327
52P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.28641410
53ARNT_22903824_ChIP-Seq_MCF-7_Human1.27846152
54CSB_26484114_Chip-Seq_FIBROBLAST_Human1.26121983
55TET1_21490601_ChIP-Seq_MESCs_Mouse1.25122305
56OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.23585664
57EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.22011741
58PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.21778225
59DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21120884
60EZH2_27304074_Chip-Seq_ESCs_Mouse1.20389584
61MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse1.20109174
62RNF2_27304074_Chip-Seq_ESCs_Mouse1.18505175
63SMC4_20622854_ChIP-Seq_HELA_Human1.18460956
64P53_21459846_ChIP-Seq_SAOS-2_Human1.17970008
65AHR_22903824_ChIP-Seq_MCF-7_Human1.17646366
66SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.16404841
67SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.16404841
68RACK7_27058665_Chip-Seq_MCF-7_Human1.16044272
69NANOG_20526341_ChIP-Seq_ESCs_Human1.15869474
70SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.15563416
71GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.14819268
72SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.14272197
73ZNF217_24962896_ChIP-Seq_MCF-7_Human1.13723299
74ERG_21242973_ChIP-ChIP_JURKAT_Human1.11774977
75E2F1_20622854_ChIP-Seq_HELA_Human1.11657108
76* TAF2_19829295_ChIP-Seq_ESCs_Human1.11626937
77EZH2_27294783_Chip-Seq_ESCs_Mouse1.11051959
78ZFP281_27345836_Chip-Seq_ESCs_Mouse1.10677857
79BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.10254957
80RARG_19884340_ChIP-ChIP_MEFs_Mouse1.10081945
81EZH2_18974828_ChIP-Seq_MESCs_Mouse1.09814154
82RNF2_18974828_ChIP-Seq_MESCs_Mouse1.09814154
83SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09747187
84GATA6_21074721_ChIP-Seq_CACO-2_Human1.09708763
85LXR_22292898_ChIP-Seq_THP-1_Human1.09049735
86YY1_22570637_ChIP-Seq_MALME-3M_Human1.08872313
87JARID2_20064375_ChIP-Seq_MESCs_Mouse1.07652137
88MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.07647609
89THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07206282
90CREB1_26743006_Chip-Seq_LNCaP_Human1.07181539
91AR_19668381_ChIP-Seq_PC3_Human1.07164763
92ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.05809624
93UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.05421135
94RING1B_27294783_Chip-Seq_ESCs_Mouse1.03867117
95TP53_18474530_ChIP-ChIP_U2OS_Human1.03315226
96PIAS1_25552417_ChIP-Seq_VCAP_Human1.03043507
97PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.02836773
98* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.01058905
99CEBPB_22108803_ChIP-Seq_LS180_Human1.00093468
100EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.99844469
101E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.99097580
102SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98417960
103SOX2_20726797_ChIP-Seq_SW620_Human0.97565623
104WT1_25993318_ChIP-Seq_PODOCYTE_Human0.97454526
105SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.97398968
106UBF1/2_26484160_Chip-Seq_HMECs_Human0.97382438
107CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97017055
108VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.96910240
109KLF5_25053715_ChIP-Seq_YYC3_Human0.96802081
110GATA3_24758297_ChIP-Seq_MCF-7_Human0.96693174
111KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.95816982
112YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95797785
113ZNF263_19887448_ChIP-Seq_K562_Human0.95562342
114EED_16625203_ChIP-ChIP_MESCs_Mouse0.95476308
115RXR_22108803_ChIP-Seq_LS180_Human0.95199170
116OCT4_19829295_ChIP-Seq_ESCs_Human0.94972992
117PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93131043
118NR3C1_23031785_ChIP-Seq_PC12_Mouse0.92293687
119SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.92003239
120SA1_27219007_Chip-Seq_ERYTHROID_Human0.91566478
121TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90370821
122GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.89897837
123BMI1_23680149_ChIP-Seq_NPCS_Mouse0.89640512
124CJUN_26792858_Chip-Seq_BT549_Human0.89547871
125ELF1_20517297_ChIP-Seq_JURKAT_Human0.88375547
126KDM2B_26808549_Chip-Seq_DND41_Human0.87838130
127BCAT_22108803_ChIP-Seq_LS180_Human0.87827966
128SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.87450430
129GATA4_25053715_ChIP-Seq_YYC3_Human0.87305194
130BCL6_27268052_Chip-Seq_Bcells_Human0.87260170
131BCOR_27268052_Chip-Seq_Bcells_Human0.86766545
132SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.86328423
133SOX2_21211035_ChIP-Seq_LN229_Gbm0.85321657
134KDM2B_26808549_Chip-Seq_SUP-B15_Human0.85133845
135RUNX1_27514584_Chip-Seq_MCF-7_Human0.84393287
136P300_27058665_Chip-Seq_ZR-75-30cells_Human0.84391651
137SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.83581353
138BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.80870259
139CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.80842468
140ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.80817405
141ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.80568342
142RING1B_27294783_Chip-Seq_NPCs_Mouse0.80288965
143KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.79688115
144IKZF1_21737484_ChIP-ChIP_HCT116_Human0.79594827
145P68_20966046_ChIP-Seq_HELA_Human0.79430301
146ZFP57_27257070_Chip-Seq_ESCs_Mouse0.78666654
147MTF2_20144788_ChIP-Seq_MESCs_Mouse0.78634697
148SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.78452119
149MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.78154027
150TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.77245934
151AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.76750299
152TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.76628788
153ATF3_27146783_Chip-Seq_COLON_Human0.75937292
154TAF15_26573619_Chip-Seq_HEK293_Human0.75668734
155RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.75105936
156JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.73558496
157NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.72901624
158CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.72454682
159GATA2_21666600_ChIP-Seq_HMVEC_Human0.72260252

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000579_abnormal_nail_morphology7.04819264
2MP0002796_impaired_skin_barrier6.80190873
3MP0005275_abnormal_skin_tensile6.03253397
4MP0002098_abnormal_vibrissa_morphology5.80391098
5MP0000647_abnormal_sebaceous_gland5.44351103
6MP0004859_abnormal_synaptic_plasticity5.15296318
7MP0000383_abnormal_hair_follicle4.71056325
8MP0004270_analgesia4.47533356
9MP0002254_reproductive_system_inflammat4.20513376
10MP0003880_abnormal_central_pattern4.17370138
11MP0010234_abnormal_vibrissa_follicle4.04988001
12MP0005501_abnormal_skin_physiology4.04248537
13MP0010678_abnormal_skin_adnexa4.03889795
14MP0000377_abnormal_hair_follicle3.63128516
15MP0000427_abnormal_hair_cycle3.51763157
16MP0005423_abnormal_somatic_nervous3.47055952
17MP0003705_abnormal_hypodermis_morpholog3.36357949
18MP0002822_catalepsy3.18559417
19MP0003635_abnormal_synaptic_transmissio3.12319660
20MP0001216_abnormal_epidermal_layer2.74678911
21MP0002734_abnormal_mechanical_nocicepti2.53359625
22MP0010771_integument_phenotype2.53200841
23MP0004947_skin_inflammation2.43246511
24MP0002060_abnormal_skin_morphology2.41572726
25MP0009745_abnormal_behavioral_response2.40664811
26MP0002063_abnormal_learning/memory/cond2.38832106
27MP0002064_seizures2.36825522
28MP0004381_abnormal_hair_follicle2.31847273
29MP0001243_abnormal_dermal_layer2.24972323
30MP0009046_muscle_twitch2.21624866
31MP0001984_abnormal_olfaction2.18821478
32MP0001529_abnormal_vocalization2.07885595
33MP0006276_abnormal_autonomic_nervous2.06936254
34MP0001968_abnormal_touch/_nociception2.04929994
35MP0000367_abnormal_coat/_hair2.01285838
36MP0002572_abnormal_emotion/affect_behav1.97631303
37MP0000778_abnormal_nervous_system1.95935314
38MP0001486_abnormal_startle_reflex1.93803952
39MP0002735_abnormal_chemical_nociception1.92532638
40MP0002272_abnormal_nervous_system1.91187822
41MP0003453_abnormal_keratinocyte_physiol1.89004484
42MP0003329_amyloid_beta_deposits1.77171236
43MP0001502_abnormal_circadian_rhythm1.71441204
44MP0003122_maternal_imprinting1.70761529
45MP0004811_abnormal_neuron_physiology1.69471966
46MP0009379_abnormal_foot_pigmentation1.68678308
47MP0003879_abnormal_hair_cell1.65664746
48MP0009931_abnormal_skin_appearance1.59338810
49MP0002184_abnormal_innervation1.58196732
50MP0002234_abnormal_pharynx_morphology1.57315624
51MP0003566_abnormal_cell_adhesion1.55161075
52MP0005394_taste/olfaction_phenotype1.54707852
53MP0005499_abnormal_olfactory_system1.54707852
54MP0003941_abnormal_skin_development1.49563432
55MP0000467_abnormal_esophagus_morphology1.48902286
56MP0001970_abnormal_pain_threshold1.47626940
57MP0003787_abnormal_imprinting1.47202442
58MP0000762_abnormal_tongue_morphology1.45485212
59MP0005645_abnormal_hypothalamus_physiol1.43053203
60MP0000955_abnormal_spinal_cord1.42729191
61MP0002095_abnormal_skin_pigmentation1.41028109
62MP0001485_abnormal_pinna_reflex1.40061852
63MP0004185_abnormal_adipocyte_glucose1.36531953
64MP0002882_abnormal_neuron_morphology1.35461542
65MP0009780_abnormal_chondrocyte_physiolo1.34120797
66MP0002736_abnormal_nociception_after1.31827041
67MP0002557_abnormal_social/conspecific_i1.30380006
68MP0002067_abnormal_sensory_capabilities1.30192752
69MP0002733_abnormal_thermal_nociception1.30075504
70MP0004924_abnormal_behavior1.27230502
71MP0005386_behavior/neurological_phenoty1.27230502
72MP0008569_lethality_at_weaning1.25190577
73MP0000537_abnormal_urethra_morphology1.23034515
74MP0005409_darkened_coat_color1.17259189
75MP0008438_abnormal_cutaneous_collagen1.17134694
76MP0001191_abnormal_skin_condition1.15943032
77MP0001177_atelectasis1.13453787
78MP0005646_abnormal_pituitary_gland1.13029444
79MP0002066_abnormal_motor_capabilities/c1.12636448
80MP0003633_abnormal_nervous_system1.05109131
81MP0002909_abnormal_adrenal_gland1.04078581
82MP0009053_abnormal_anal_canal1.02686870
83MP0001501_abnormal_sleep_pattern1.01480610
84MP0001905_abnormal_dopamine_level1.01383126
85MP0002152_abnormal_brain_morphology0.98058229
86MP0001440_abnormal_grooming_behavior0.92970229
87MP0003631_nervous_system_phenotype0.91850716
88MP0001346_abnormal_lacrimal_gland0.91687134
89MP0004885_abnormal_endolymph0.86476971
90MP0002752_abnormal_somatic_nervous0.85687037
91MP0002069_abnormal_eating/drinking_beha0.84138774
92MP0000462_abnormal_digestive_system0.83631613
93MP0004858_abnormal_nervous_system0.83265911
94MP0003121_genomic_imprinting0.81800045
95MP0005187_abnormal_penis_morphology0.80827831
96MP0004782_abnormal_surfactant_physiolog0.79653577
97MP0004264_abnormal_extraembryonic_tissu0.78324372
98MP0002229_neurodegeneration0.77196953
99MP0001664_abnormal_digestion0.75457999
100MP0003123_paternal_imprinting0.74883058
101MP0001340_abnormal_eyelid_morphology0.74290640
102MP0001188_hyperpigmentation0.74215305
103MP0002102_abnormal_ear_morphology0.72067994
104MP0008874_decreased_physiological_sensi0.71787598
105MP0004742_abnormal_vestibular_system0.69667678
106MP0003861_abnormal_nervous_system0.69348342
107MP0001661_extended_life_span0.68793263
108MP0008872_abnormal_physiological_respon0.67998432
109MP0001784_abnormal_fluid_regulation0.67696006
110MP0002177_abnormal_outer_ear0.66603928
111MP0002638_abnormal_pupillary_reflex0.65955148
112MP0010030_abnormal_orbit_morphology0.65659233
113MP0003191_abnormal_cellular_cholesterol0.64889880
114MP0001943_abnormal_respiration0.64758707
115MP0003385_abnormal_body_wall0.63842324
116MP0002653_abnormal_ependyma_morphology0.63205094
117MP0002249_abnormal_larynx_morphology0.62977328
118MP0003632_abnormal_nervous_system0.62881649
119MP0001849_ear_inflammation0.62305055
120MP0002082_postnatal_lethality0.61256613
121MP0010770_preweaning_lethality0.61256613
122MP0000566_synostosis0.60767619
123MP0000026_abnormal_inner_ear0.60518431
124MP0001963_abnormal_hearing_physiology0.59864843
125MP0000627_abnormal_mammary_gland0.59184723
126MP0002282_abnormal_trachea_morphology0.58166922
127MP0001851_eye_inflammation0.57863194
128MP0002877_abnormal_melanocyte_morpholog0.55903791
129MP0001879_abnormal_lymphatic_vessel0.54385637
130MP0000569_abnormal_digit_pigmentation0.53780510
131MP0003755_abnormal_palate_morphology0.52298334
132MP0009384_cardiac_valve_regurgitation0.51833613
133MP0000751_myopathy0.49728931
134MP0005451_abnormal_body_composition0.49094136
135MP0005023_abnormal_wound_healing0.47734577
136MP0002089_abnormal_postnatal_growth/wei0.41791194
137MP0005174_abnormal_tail_pigmentation0.40907483
138MP0002111_abnormal_tail_morphology0.40760618
139MP0000432_abnormal_head_morphology0.35056147
140MP0003300_gastrointestinal_ulcer0.34767759
141MP0000465_gastrointestinal_hemorrhage0.31941035
142MP0000747_muscle_weakness0.31876651
143MP0002009_preneoplasia0.31776471
144MP0005666_abnormal_adipose_tissue0.31740819
145MP0001958_emphysema0.31363930
146MP0005248_abnormal_Harderian_gland0.31216916
147MP0004272_abnormal_basement_membrane0.30896867
148MP0002970_abnormal_white_adipose0.30244344
149MP0000015_abnormal_ear_pigmentation0.29487571
150MP0005508_abnormal_skeleton_morphology0.28171409
151MP0005623_abnormal_meninges_morphology0.28006319
152MP0002697_abnormal_eye_size0.27576594
153MP0002166_altered_tumor_susceptibility0.23794674
154MP0003935_abnormal_craniofacial_develop0.23373905
155MP0005257_abnormal_intraocular_pressure0.23271986
156MP0003315_abnormal_perineum_morphology0.22710464
157MP0000749_muscle_degeneration0.21377329
158MP0003638_abnormal_response/metabolism_0.20909456
159MP0000733_abnormal_muscle_development0.20626496
160MP0000678_abnormal_parathyroid_gland0.20224230
161MP0001881_abnormal_mammary_gland0.18790699
162MP0005075_abnormal_melanosome_morpholog0.18571872
163MP0000428_abnormal_craniofacial_morphol0.18260815
164MP0005503_abnormal_tendon_morphology0.18066727
165MP0002896_abnormal_bone_mineralization0.17685805
166MP0003045_fibrosis0.17550952
167MP0001853_heart_inflammation0.16015455
168MP0002006_tumorigenesis0.15901483
169MP0005375_adipose_tissue_phenotype0.15299184
170MP0009250_abnormal_appendicular_skeleto0.15141148
171MP0005193_abnormal_anterior_eye0.15092466
172MP0002295_abnormal_pulmonary_circulatio0.15023707
173MP0002109_abnormal_limb_morphology0.14192164
174MP0000750_abnormal_muscle_regeneration0.14141551
175MP0009333_abnormal_splenocyte_physiolog0.14012065
176MP0005171_absent_coat_pigmentation0.13356653

Predicted human phenotypes

RankGene SetZ-score
1Slow-growing hair (HP:0002217)7.54221275
2Abnormality of hair growth rate (HP:0011363)7.54221275
3Brittle hair (HP:0002299)7.02114066
4Abnormal hair laboratory examination (HP:0003328)6.77232320
5Increased IgE level (HP:0003212)6.65556922
6Abnormality of nail color (HP:0100643)5.97679474
7Fragile nails (HP:0001808)5.53019608
8Nail dystrophy (HP:0008404)5.40265586
9Onycholysis (HP:0001806)5.16518507
10Myokymia (HP:0002411)5.15140672
11Alopecia of scalp (HP:0002293)5.13180810
12Follicular hyperkeratosis (HP:0007502)5.06827889
13Palmoplantar hyperkeratosis (HP:0000972)5.06440896
14Ankle clonus (HP:0011448)4.80477793
15Erythema (HP:0010783)4.77575159
16Palmar hyperkeratosis (HP:0010765)4.74532823
17Plantar hyperkeratosis (HP:0007556)4.64308227
18Right ventricular cardiomyopathy (HP:0011663)4.49930795
19Atonic seizures (HP:0010819)4.09423689
20Thick nail (HP:0001805)4.07416688
21Urinary urgency (HP:0000012)3.93215435
22Focal seizures (HP:0007359)3.83388327
23Fine hair (HP:0002213)3.81258794
24Epileptic encephalopathy (HP:0200134)3.78461557
25Focal motor seizures (HP:0011153)3.70210525
26Erythroderma (HP:0001019)3.68651112
27Sparse eyelashes (HP:0000653)3.50641974
28Absent eyebrow (HP:0002223)3.43069991
29Abnormality of the frontal sinuses (HP:0002687)3.30948691
30Progressive cerebellar ataxia (HP:0002073)3.29407803
31Spastic gait (HP:0002064)3.29171145
32Congenital, generalized hypertrichosis (HP:0004540)3.29118498
33Action tremor (HP:0002345)3.29011414
34Febrile seizures (HP:0002373)3.26588541
35Postural instability (HP:0002172)3.24986575
36Akinesia (HP:0002304)3.06631427
37Amelogenesis imperfecta (HP:0000705)3.03267972
38Polyphagia (HP:0002591)3.02682473
39Depression (HP:0000716)2.97390948
40Congenital ichthyosiform erythroderma (HP:0007431)2.95365035
41Oral leukoplakia (HP:0002745)2.95104420
42Conjunctival hamartoma (HP:0100780)2.91125587
43Milia (HP:0001056)2.89667191
44Curly hair (HP:0002212)2.85495052
45Supranuclear gaze palsy (HP:0000605)2.85162880
46Epileptiform EEG discharges (HP:0011182)2.76780363
47Abnormal blistering of the skin (HP:0008066)2.67815140
48Mutism (HP:0002300)2.67227020
49Truncal ataxia (HP:0002078)2.65656505
50Urinary bladder sphincter dysfunction (HP:0002839)2.64944187
51Type 1 muscle fiber predominance (HP:0003803)2.64805788
52Parakeratosis (HP:0001036)2.64776215
53Abnormal eating behavior (HP:0100738)2.64332810
54EEG with generalized epileptiform discharges (HP:0011198)2.59926432
55Aplasia cutis congenita (HP:0001057)2.58938457
56Poor eye contact (HP:0000817)2.58148382
57Generalized tonic-clonic seizures (HP:0002069)2.55823728
58Abnormality of the corticospinal tract (HP:0002492)2.54822447
59Round ear (HP:0100830)2.54593737
60Limb dystonia (HP:0002451)2.54333547
61Concave nail (HP:0001598)2.54272887
62Dialeptic seizures (HP:0011146)2.51837009
63Advanced eruption of teeth (HP:0006288)2.50000034
64Hypsarrhythmia (HP:0002521)2.48711197
65Absence seizures (HP:0002121)2.47292863
66Ridged nail (HP:0001807)2.47078660
67Genetic anticipation (HP:0003743)2.47037985
68Ventricular tachycardia (HP:0004756)2.44073795
69Impaired social interactions (HP:0000735)2.42284740
70Abnormal social behavior (HP:0012433)2.42284740
71Drooling (HP:0002307)2.38782167
72Amblyopia (HP:0000646)2.38489425
73Resting tremor (HP:0002322)2.38089633
74Ulnar claw (HP:0001178)2.33287362
75Absent hair (HP:0002298)2.29558191
76Visual hallucinations (HP:0002367)2.27550313
77Failure to thrive in infancy (HP:0001531)2.27058688
78Impaired vibration sensation in the lower limbs (HP:0002166)2.26646095
79Lower limb muscle weakness (HP:0007340)2.26607794
80Dysmetria (HP:0001310)2.25123114
81Palmoplantar keratoderma (HP:0000982)2.22327838
82Excessive salivation (HP:0003781)2.21273393
83Abnormality of the lower motor neuron (HP:0002366)2.21098177
84Corneal erosion (HP:0200020)2.21068895
85Agitation (HP:0000713)2.19778716
86Natal tooth (HP:0000695)2.18655343
87Intention tremor (HP:0002080)2.15623338
88Neck muscle weakness (HP:0000467)2.15184662
89Hyporeflexia of lower limbs (HP:0002600)2.14523577
90Foot dorsiflexor weakness (HP:0009027)2.12573861
91Apathy (HP:0000741)2.11652028
92Clonus (HP:0002169)2.11508868
93Aplasia/Hypoplasia of the brainstem (HP:0007362)2.11478634
94Hypoplasia of the brainstem (HP:0002365)2.11478634
95Abnormality of molar (HP:0011077)2.11298180
96Abnormality of molar morphology (HP:0011070)2.11298180
97Anxiety (HP:0000739)2.11131052
98Lower limb amyotrophy (HP:0007210)2.09781459
99Clumsiness (HP:0002312)2.09423220
100Morphological abnormality of the pyramidal tract (HP:0002062)2.07558687
101Abnormality of the dental root (HP:0006486)2.07545582
102Taurodontia (HP:0000679)2.07545582
103Abnormality of permanent molar morphology (HP:0011071)2.07545582
104Pruritus (HP:0000989)2.05676040
105Bradykinesia (HP:0002067)2.04768659
106Hyperventilation (HP:0002883)2.04497678
107Eczematoid dermatitis (HP:0000976)2.03672866
108Abnormality of the foot musculature (HP:0001436)2.03387046
109Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.03079256
110Distal arthrogryposis (HP:0005684)2.01802544
111Broad-based gait (HP:0002136)2.01565499
112Status epilepticus (HP:0002133)2.01280210
113Hypotrichosis (HP:0001006)11.9369021
114Pili torti (HP:0003777)10.2328117
115Woolly hair (HP:0002224)10.1961523
116Steppage gait (HP:0003376)1.99570219
117Hypohidrosis (HP:0000966)1.98024375
118Increased connective tissue (HP:0009025)1.97948132
119Gangrene (HP:0100758)1.96724847
120Scapular winging (HP:0003691)1.96369790
121Rapidly progressive (HP:0003678)1.95608350
122Absent speech (HP:0001344)1.94400126
123Diplopia (HP:0000651)1.90345644
124Abnormality of binocular vision (HP:0011514)1.90345644
125Dry hair (HP:0011359)1.89371541
126Neurofibrillary tangles (HP:0002185)1.88571424
127Nemaline bodies (HP:0003798)1.86858458
128Diminished motivation (HP:0000745)1.86653115
129Atrophic scars (HP:0001075)1.85867737
130Spastic tetraplegia (HP:0002510)1.85059874
131Amyotrophic lateral sclerosis (HP:0007354)1.84523898
132Muscle fiber inclusion bodies (HP:0100299)1.83318603
133Hypoventilation (HP:0002791)1.82768540
134Abnormality of the shoulder girdle musculature (HP:0001435)1.82100383
135Abnormality of the parietal bone (HP:0002696)1.82006618
136Cerebral inclusion bodies (HP:0100314)1.81887576
137Hamartoma of the eye (HP:0010568)1.81571878
138Sleep apnea (HP:0010535)1.80683995
139Abnormality of the dental pulp (HP:0006479)1.80228682
140Bronchomalacia (HP:0002780)1.79552333
141Laryngomalacia (HP:0001601)1.79114006
142Hypergammaglobulinemia (HP:0010702)1.78088482
143Calcaneovalgus deformity (HP:0001848)1.77129432
144Peripheral hypomyelination (HP:0007182)1.75294800
145Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.75269502
146Morphological abnormality of the middle ear (HP:0008609)1.75174033
147Hemiplegia (HP:0002301)1.73830347
148Stereotypic behavior (HP:0000733)1.73778541
149Hand muscle atrophy (HP:0009130)1.72740994
150Widely patent fontanelles and sutures (HP:0004492)1.72074388
151Fetal akinesia sequence (HP:0001989)1.71138495
152Dysdiadochokinesis (HP:0002075)1.70537670
153Craniofacial hyperostosis (HP:0004493)1.70167706
154Ulnar deviation of the wrist (HP:0003049)1.68632532
155Lip pit (HP:0100267)1.63551665
156Absent eyelashes (HP:0000561)1.62630551
157Fatigable weakness (HP:0003473)1.61720291
158Abnormality of the neuromuscular junction (HP:0003398)1.61720291
159Sudden death (HP:0001699)1.61011311
160Acanthosis nigricans (HP:0000956)1.57470197
161Abnormality of the aortic arch (HP:0012303)1.55811751
162Fragile skin (HP:0001030)1.53566629
163Deformed tarsal bones (HP:0008119)1.53371962
164Keratoconjunctivitis sicca (HP:0001097)1.51756197
165Abnormality of dental color (HP:0011073)1.51507134
166Torticollis (HP:0000473)1.51465511
167Recurrent corneal erosions (HP:0000495)1.49432293
168Unilateral renal agenesis (HP:0000122)1.46985580
169Ventricular fibrillation (HP:0001663)1.46382828
170Difficulty walking (HP:0002355)1.46248887
171Blepharitis (HP:0000498)1.45985014
172Distal lower limb muscle weakness (HP:0009053)1.45442451
173Lack of skin elasticity (HP:0100679)1.43702698
174Protrusio acetabuli (HP:0003179)1.41730222
175Abnormality of placental membranes (HP:0011409)1.41369296
176Amniotic constriction ring (HP:0009775)1.41369296
177Corneal dystrophy (HP:0001131)1.40264777
178Abnormality of skeletal muscle fiber size (HP:0012084)1.38343450
179Obstructive sleep apnea (HP:0002870)1.36243807
180Premature rupture of membranes (HP:0001788)1.35208826
181Exercise-induced myalgia (HP:0003738)1.34166334
182Widely spaced teeth (HP:0000687)1.32918960

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.26122612
2PINK14.70615824
3MST1R4.19290251
4FER3.57480504
5CASK3.12299081
6PIK3CG3.10108932
7MAP2K73.04234094
8MAP3K92.96681353
9TTN2.85714019
10EPHA42.76231468
11EPHB22.65416196
12OBSCN2.61979818
13EPHA22.51854580
14LATS12.32244628
15SIK22.23867873
16MINK12.23813351
17ERN12.17062958
18MAP3K42.16297217
19MAP3K32.13371269
20MAPKAPK32.12760713
21MAP3K22.06558834
22NTRK31.93864358
23FGFR21.92598418
24FGFR11.92107707
25EPHB11.89421678
26MET1.88389613
27TRIB31.83951864
28ERBB41.72886783
29EPHA31.71777819
30BMX1.70202292
31JAK31.65575800
32ICK1.61104539
33TAOK11.58957752
34DAPK21.56171114
35BCR1.53547351
36MAP3K111.49208569
37TESK11.44107362
38CDK51.40443785
39FGFR31.40016129
40MAP3K61.38823808
41LATS21.36528293
42MAPK131.36159079
43SGK2231.35350125
44SGK4941.35350125
45TRIM281.33362833
46FGFR41.32709938
47NTRK21.30170079
48NTRK11.29131688
49PKN21.28567405
50MAPK121.28002662
51CSNK1A1L1.23435032
52CAMKK11.22062195
53PHKG11.22052196
54PHKG21.22052196
55UHMK11.18551139
56DYRK21.17633581
57CAMK2B1.17336964
58CSNK1G11.14573924
59MAP2K41.12770542
60SIK31.12599238
61RPS6KB21.10106233
62CDK141.09889692
63PBK1.09555851
64MARK21.08707647
65CDK61.05851663
66KSR21.04301578
67RET1.01759753
68CSNK1G31.01213955
69BTK0.98503935
70PRKD30.98415624
71MAP3K10.96622282
72DDR20.93186790
73JAK20.92240870
74TIE10.90764978
75MAPKAPK20.88207773
76SIK10.87527713
77CDK180.86629543
78PRKCG0.85298450
79RPS6KB10.83943522
80PDPK10.83654367
81NEK60.83514615
82CDK150.83353345
83ERBB30.82360738
84SGK20.82329306
85FGR0.80338375
86CSNK1G20.79767409
87KSR10.79530605
88STK110.79193596
89PDK10.78333192
90JAK10.77939927
91MAP3K70.77414368
92CDK11A0.76505835
93FES0.76053399
94RPS6KA10.74214953
95MAP2K60.74051221
96NLK0.73433234
97MAPK40.72878939
98MARK30.69456196
99DAPK10.67471953
100RPS6KA20.66452892
101PIK3CA0.65395767
102CAMK2A0.64209574
103DYRK1A0.63989101
104PRKG20.59815635
105CDK30.58756725
106SYK0.57882243
107MUSK0.57326068
108CAMK2G0.56606052
109MAPK150.54863244
110PRKAA10.53674306
111GSK3A0.53122456
112LIMK10.53096249
113HIPK20.52181100
114SGK30.52028835
115PDGFRA0.51932860
116PTK60.51683502
117LRRK20.50834303
118TYRO30.50649870
119DMPK0.49044773
120LMTK20.48163796
121CAMK10.47920654
122EEF2K0.46709419
123CAMK2D0.45749060
124PRKCZ0.45010662
125ARAF0.44753182
126DYRK30.43493759
127PTK20.43010838
128PAK60.43001189
129MAP2K30.42991068
130PRKCH0.42013647
131GRK70.41656952
132SCYL20.40818808
133PRKD10.40736833
134STK380.40652613
135DYRK1B0.39985701
136MAPK80.39638267
137MAP3K80.39452248
138HCK0.39094648
139PRKD20.38683989
140PAK30.38641739
141GRK60.38075115
142MAP2K10.37267838
143SRC0.36547126
144CSNK1A10.35415110
145RIPK10.34909790
146NME10.34430334
147TGFBR10.33742690
148MAP3K50.33696698
149INSRR0.33514513
150STK30.33152915
151NME20.32714574
152TRPM70.32407897
153ALK0.31190402
154CDK190.31133662
155TGFBR20.29837579
156CAMK40.29213465
157PKN10.29140928
158MAPK90.28746706
159ERBB20.28267355
160PRKACA0.27793861
161CSNK1D0.26067194

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.00801983
2Fatty acid elongation_Homo sapiens_hsa000623.82350307
3Synaptic vesicle cycle_Homo sapiens_hsa047213.59835763
4GABAergic synapse_Homo sapiens_hsa047272.65319786
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.41129234
6Linoleic acid metabolism_Homo sapiens_hsa005912.38993026
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.31402897
8Glutamatergic synapse_Homo sapiens_hsa047242.23632499
9Amphetamine addiction_Homo sapiens_hsa050312.17038137
10Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.16521946
11Dopaminergic synapse_Homo sapiens_hsa047282.05175752
12Cocaine addiction_Homo sapiens_hsa050302.00572809
13Morphine addiction_Homo sapiens_hsa050321.95878779
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.76090947
15Basal cell carcinoma_Homo sapiens_hsa052171.76047498
16Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.74758938
17Histidine metabolism_Homo sapiens_hsa003401.70363734
18Melanogenesis_Homo sapiens_hsa049161.69107111
19Long-term potentiation_Homo sapiens_hsa047201.58454889
20Insulin secretion_Homo sapiens_hsa049111.58088440
21Cholinergic synapse_Homo sapiens_hsa047251.55485977
22Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.55428535
23Phenylalanine metabolism_Homo sapiens_hsa003601.45689453
24Fat digestion and absorption_Homo sapiens_hsa049751.43336263
25Axon guidance_Homo sapiens_hsa043601.42494830
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41486516
27Collecting duct acid secretion_Homo sapiens_hsa049661.40722081
28GnRH signaling pathway_Homo sapiens_hsa049121.36413165
29Taste transduction_Homo sapiens_hsa047421.36181799
30Glioma_Homo sapiens_hsa052141.35609314
31Proteoglycans in cancer_Homo sapiens_hsa052051.33456044
32PPAR signaling pathway_Homo sapiens_hsa033201.30119064
33Vibrio cholerae infection_Homo sapiens_hsa051101.27489234
34beta-Alanine metabolism_Homo sapiens_hsa004101.27109780
35VEGF signaling pathway_Homo sapiens_hsa043701.26346726
36Ether lipid metabolism_Homo sapiens_hsa005651.24682513
37Long-term depression_Homo sapiens_hsa047301.24662496
38Acute myeloid leukemia_Homo sapiens_hsa052211.23104452
39AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.21587828
40Gastric acid secretion_Homo sapiens_hsa049711.20856687
41Leukocyte transendothelial migration_Homo sapiens_hsa046701.18953127
42ECM-receptor interaction_Homo sapiens_hsa045121.18509652
43Adherens junction_Homo sapiens_hsa045201.17060804
44Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15268999
45Type II diabetes mellitus_Homo sapiens_hsa049301.13845002
46Tight junction_Homo sapiens_hsa045301.12986924
47Non-small cell lung cancer_Homo sapiens_hsa052231.11855302
48Renin secretion_Homo sapiens_hsa049241.11000806
49Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.10681927
50Amoebiasis_Homo sapiens_hsa051461.10051367
51Butanoate metabolism_Homo sapiens_hsa006501.07463943
52Vascular smooth muscle contraction_Homo sapiens_hsa042701.07304508
53Hippo signaling pathway_Homo sapiens_hsa043901.07035299
54cAMP signaling pathway_Homo sapiens_hsa040241.04153902
55Tyrosine metabolism_Homo sapiens_hsa003501.01483810
56Dorso-ventral axis formation_Homo sapiens_hsa043201.01443226
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.99695265
58Steroid biosynthesis_Homo sapiens_hsa001000.99114570
59Salivary secretion_Homo sapiens_hsa049700.97131419
60Protein digestion and absorption_Homo sapiens_hsa049740.96980648
61Serotonergic synapse_Homo sapiens_hsa047260.96684476
62Wnt signaling pathway_Homo sapiens_hsa043100.96254384
63Arachidonic acid metabolism_Homo sapiens_hsa005900.93692612
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93415412
65Nitrogen metabolism_Homo sapiens_hsa009100.92987803
66Pancreatic secretion_Homo sapiens_hsa049720.92962146
67Staphylococcus aureus infection_Homo sapiens_hsa051500.92529896
68Rap1 signaling pathway_Homo sapiens_hsa040150.91838737
69Phototransduction_Homo sapiens_hsa047440.89735926
70Hedgehog signaling pathway_Homo sapiens_hsa043400.88792963
71MicroRNAs in cancer_Homo sapiens_hsa052060.86870100
72Bladder cancer_Homo sapiens_hsa052190.86497625
73ErbB signaling pathway_Homo sapiens_hsa040120.85791645
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84727259
75Platelet activation_Homo sapiens_hsa046110.83156037
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82988217
77Oxytocin signaling pathway_Homo sapiens_hsa049210.82070298
78Estrogen signaling pathway_Homo sapiens_hsa049150.81767353
79Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.80606212
80Dilated cardiomyopathy_Homo sapiens_hsa054140.79314949
81AMPK signaling pathway_Homo sapiens_hsa041520.78310816
82Thyroid cancer_Homo sapiens_hsa052160.77082947
83Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76383407
84Focal adhesion_Homo sapiens_hsa045100.76216416
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.74073905
86Sphingolipid metabolism_Homo sapiens_hsa006000.73444194
87Choline metabolism in cancer_Homo sapiens_hsa052310.72622485
88Endometrial cancer_Homo sapiens_hsa052130.71800859
89Renal cell carcinoma_Homo sapiens_hsa052110.71322375
90Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.70956263
91Complement and coagulation cascades_Homo sapiens_hsa046100.70097021
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68992264
93Mineral absorption_Homo sapiens_hsa049780.68779315
94Insulin signaling pathway_Homo sapiens_hsa049100.68631705
95Ras signaling pathway_Homo sapiens_hsa040140.67220862
96Pertussis_Homo sapiens_hsa051330.66706401
97Circadian rhythm_Homo sapiens_hsa047100.66295529
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65847322
99Gap junction_Homo sapiens_hsa045400.65582218
100Glucagon signaling pathway_Homo sapiens_hsa049220.65397909
101Insulin resistance_Homo sapiens_hsa049310.65307347
102Oocyte meiosis_Homo sapiens_hsa041140.64983146
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64136503
104Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.63652452
105MAPK signaling pathway_Homo sapiens_hsa040100.62252060
106TGF-beta signaling pathway_Homo sapiens_hsa043500.61588478
107Arginine biosynthesis_Homo sapiens_hsa002200.60284331
108Alcoholism_Homo sapiens_hsa050340.59272666
109Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.58491791
110Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58086594
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57825352
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57516255
113Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55908074
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53926135
115Chronic myeloid leukemia_Homo sapiens_hsa052200.52754914
116Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52392318
117Fatty acid metabolism_Homo sapiens_hsa012120.52102760
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.52051905
119Malaria_Homo sapiens_hsa051440.51815981
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.51695415
121Salmonella infection_Homo sapiens_hsa051320.51333890
122Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51216086
123Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.50816357
124Central carbon metabolism in cancer_Homo sapiens_hsa052300.50355337
125Ovarian steroidogenesis_Homo sapiens_hsa049130.49278008
126Fatty acid degradation_Homo sapiens_hsa000710.48838583
127Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.48343884
128Calcium signaling pathway_Homo sapiens_hsa040200.47952229
129Regulation of autophagy_Homo sapiens_hsa041400.47297724
130Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47106116
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.47008025
132Fatty acid biosynthesis_Homo sapiens_hsa000610.45691738
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45387463
134mTOR signaling pathway_Homo sapiens_hsa041500.44587794
135Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44476410
136Pathways in cancer_Homo sapiens_hsa052000.43981298
137Caffeine metabolism_Homo sapiens_hsa002320.43565546
138Circadian entrainment_Homo sapiens_hsa047130.43546954
139Endocytosis_Homo sapiens_hsa041440.43428760
140Melanoma_Homo sapiens_hsa052180.42987109
141Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.42840954
142Chemical carcinogenesis_Homo sapiens_hsa052040.42054200
143Phospholipase D signaling pathway_Homo sapiens_hsa040720.41717170
144Olfactory transduction_Homo sapiens_hsa047400.41438768
145Bile secretion_Homo sapiens_hsa049760.41154665
146Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.40998138
147Prolactin signaling pathway_Homo sapiens_hsa049170.40979351
148Thyroid hormone synthesis_Homo sapiens_hsa049180.37218320
149Inositol phosphate metabolism_Homo sapiens_hsa005620.37214784
150Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.31493304
151Cardiac muscle contraction_Homo sapiens_hsa042600.31475694

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »