KRTCAP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.55647565
2viral transcription (GO:0019083)5.32840057
3translational termination (GO:0006415)5.14942360
4maturation of SSU-rRNA (GO:0030490)5.09209320
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.08487008
6protein targeting to ER (GO:0045047)4.94554149
7cotranslational protein targeting to membrane (GO:0006613)4.91900691
8establishment of protein localization to endoplasmic reticulum (GO:0072599)4.67952622
9ribosomal small subunit biogenesis (GO:0042274)4.66925646
10protein localization to endoplasmic reticulum (GO:0070972)4.61495320
11rRNA methylation (GO:0031167)4.60256572
12translational elongation (GO:0006414)4.58993568
13establishment of apical/basal cell polarity (GO:0035089)4.40441194
14intestinal epithelial cell development (GO:0060576)4.36445748
15DNA deamination (GO:0045006)4.30555524
16viral life cycle (GO:0019058)4.22025838
17Golgi transport vesicle coating (GO:0048200)4.11827038
18COPI coating of Golgi vesicle (GO:0048205)4.11827038
19proteasome assembly (GO:0043248)4.11125847
20GDP-mannose metabolic process (GO:0019673)4.05251325
21translational initiation (GO:0006413)4.00612058
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.99717200
23cellular protein complex disassembly (GO:0043624)3.99464346
24regulation of mitochondrial translation (GO:0070129)3.91369563
25sperm capacitation (GO:0048240)3.83199287
26ribosomal large subunit biogenesis (GO:0042273)3.71108182
27fusion of sperm to egg plasma membrane (GO:0007342)3.70716820
28mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.66580716
29interferon-gamma secretion (GO:0072643)3.65587390
30L-alpha-amino acid transmembrane transport (GO:1902475)3.65221683
31single strand break repair (GO:0000012)3.61758753
32deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.60519682
33respiratory chain complex IV assembly (GO:0008535)3.55986093
34protein complex disassembly (GO:0043241)3.53948822
35proline biosynthetic process (GO:0006561)3.50764631
36polarized epithelial cell differentiation (GO:0030859)3.45753975
37protein autoprocessing (GO:0016540)3.43571672
38regulation of respiratory burst (GO:0060263)3.43379459
39bundle of His cell to Purkinje myocyte communication (GO:0086069)3.41693509
40hemidesmosome assembly (GO:0031581)3.40341265
41establishment of monopolar cell polarity (GO:0061162)3.38218854
42establishment or maintenance of monopolar cell polarity (GO:0061339)3.38218854
43sperm motility (GO:0030317)3.33256339
44glandular epithelial cell differentiation (GO:0002067)3.32304484
45macromolecular complex disassembly (GO:0032984)3.31667875
46establishment of integrated proviral latency (GO:0075713)3.29321328
47nodal signaling pathway (GO:0038092)3.28955766
48maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.27916246
49ribosome assembly (GO:0042255)3.26067948
50translation (GO:0006412)3.25591617
51formation of translation preinitiation complex (GO:0001731)3.24295938
52protein targeting to membrane (GO:0006612)3.21686968
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.20242978
54cytochrome complex assembly (GO:0017004)3.19090369
55calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.18113598
56protein retention in ER lumen (GO:0006621)3.15356872
57negative regulation of glycoprotein biosynthetic process (GO:0010561)3.10654265
58antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.10587374
59antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.10587374
60antimicrobial humoral response (GO:0019730)3.10363161
61antibacterial humoral response (GO:0019731)3.08440176
62glutathione derivative metabolic process (GO:1901685)3.03695021
63glutathione derivative biosynthetic process (GO:1901687)3.03695021
64regulation of cellular amino acid metabolic process (GO:0006521)3.03662938
65nuclear-transcribed mRNA catabolic process (GO:0000956)3.03027484
66water-soluble vitamin biosynthetic process (GO:0042364)2.98508102
67regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.98086782
68intestinal absorption (GO:0050892)2.92327479
69establishment of protein localization to mitochondrial membrane (GO:0090151)2.90642418
70hepatocyte apoptotic process (GO:0097284)2.90448971
71histone exchange (GO:0043486)2.90054849
72mRNA catabolic process (GO:0006402)2.89882692
73NADH metabolic process (GO:0006734)2.88633208
74negative regulation of ligase activity (GO:0051352)2.88356966
75negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.88356966
76desmosome organization (GO:0002934)2.87950181
77chromosome condensation (GO:0030261)2.85309609
78regulation of water loss via skin (GO:0033561)2.84311268
79keratinocyte development (GO:0003334)2.82948080
80axonemal dynein complex assembly (GO:0070286)2.82138831
81positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.81752086
82energy coupled proton transport, down electrochemical gradient (GO:0015985)2.79731708
83ATP synthesis coupled proton transport (GO:0015986)2.79731708
84regulation of chemokine secretion (GO:0090196)2.79405357
85acrosome reaction (GO:0007340)2.79140499
86pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.77370684
87UDP-N-acetylglucosamine metabolic process (GO:0006047)2.76570816
88trophectodermal cell differentiation (GO:0001829)2.75511286
89binding of sperm to zona pellucida (GO:0007339)2.75003232
90mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.74051452
91ribonucleoprotein complex biogenesis (GO:0022613)2.73784647
92paraxial mesoderm development (GO:0048339)2.71864050
93RNA catabolic process (GO:0006401)2.71008293
94endocrine pancreas development (GO:0031018)2.70880331
95nucleotide-sugar biosynthetic process (GO:0009226)2.70844315
96spermatid development (GO:0007286)2.69193218
97regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.69161531
98regulation of apoptotic process involved in morphogenesis (GO:1902337)2.69057058
99plasma membrane fusion (GO:0045026)2.68956373
100establishment of viral latency (GO:0019043)2.68503078
101glutathione biosynthetic process (GO:0006750)2.67941607
102pseudouridine synthesis (GO:0001522)2.67870952
103positive regulation of epidermal cell differentiation (GO:0045606)2.67794015
104blastocyst development (GO:0001824)2.67188744
105DNA packaging (GO:0006323)2.66575819
106regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.65242047
107regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.65201467
108protein complex localization (GO:0031503)2.64511639
109L-serine metabolic process (GO:0006563)2.64241918
110electron transport chain (GO:0022900)2.63847661
111antigen processing and presentation of endogenous antigen (GO:0019883)2.63648341
112respiratory electron transport chain (GO:0022904)2.62730662
113nonribosomal peptide biosynthetic process (GO:0019184)2.61676042
114DNA replication checkpoint (GO:0000076)2.61654907
115maintenance of gastrointestinal epithelium (GO:0030277)2.59650695
116transcytosis (GO:0045056)2.58953949
117establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.56595695
118anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.56145751
119chromatin remodeling at centromere (GO:0031055)2.55182238
120deoxyribonucleotide catabolic process (GO:0009264)2.55179805
121positive regulation of interleukin-8 secretion (GO:2000484)2.54242844
122sperm-egg recognition (GO:0035036)2.52412757
123negative regulation of keratinocyte proliferation (GO:0010839)2.52046354
124uronic acid metabolic process (GO:0006063)2.49687133
125glucuronate metabolic process (GO:0019585)2.49687133
126pteridine-containing compound biosynthetic process (GO:0042559)2.49039329
127CENP-A containing nucleosome assembly (GO:0034080)2.48958170
128DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.48616415
129negative regulation of cell fate commitment (GO:0010454)2.48406918
130positive regulation of Cdc42 GTPase activity (GO:0043089)2.48331044
131regulation of gamma-delta T cell differentiation (GO:0045586)2.47568803
132negative regulation of T cell differentiation in thymus (GO:0033085)2.47078520
133signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.45239631
134signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.45239631
135signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.45239631
136purine nucleobase biosynthetic process (GO:0009113)2.44676313
137glutathione metabolic process (GO:0006749)2.43902002
138intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.43856056
139signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.43856056
140regulation of guanylate cyclase activity (GO:0031282)2.43457276
141termination of RNA polymerase III transcription (GO:0006386)2.43380588
142transcription elongation from RNA polymerase III promoter (GO:0006385)2.43380588
143negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.42792992
144positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.41467353
145negative regulation of cell fate specification (GO:0009996)2.41417731
146lactate metabolic process (GO:0006089)2.39556209
147Leydig cell differentiation (GO:0033327)2.39387002
148pyrimidine nucleotide catabolic process (GO:0006244)2.39069190
149positive regulation of glycoprotein metabolic process (GO:1903020)2.38555205
150establishment of protein localization to membrane (GO:0090150)2.37838163
151chaperone-mediated protein transport (GO:0072321)2.37654782
152signal transduction involved in DNA integrity checkpoint (GO:0072401)2.36329011
153signal transduction involved in DNA damage checkpoint (GO:0072422)2.36329011
154positive regulation of ligase activity (GO:0051351)2.35347611
155deoxyribose phosphate catabolic process (GO:0046386)2.35267658
156tricarboxylic acid cycle (GO:0006099)2.35222478
157regulation of gamma-delta T cell activation (GO:0046643)2.34379769
158L-ascorbic acid metabolic process (GO:0019852)2.34170527
159nucleobase biosynthetic process (GO:0046112)2.33945137
160positive regulation of glycoprotein biosynthetic process (GO:0010560)2.33124300
161cellular glucuronidation (GO:0052695)2.33108127
162rRNA processing (GO:0006364)2.32531336
163folic acid-containing compound biosynthetic process (GO:0009396)2.32325588
164regulation of cellular amine metabolic process (GO:0033238)2.32240205
165proline metabolic process (GO:0006560)2.32144660
166establishment of skin barrier (GO:0061436)2.31829961
167glycerol ether metabolic process (GO:0006662)2.31652576
168columnar/cuboidal epithelial cell development (GO:0002066)2.31280332
169negative regulation of transcription by competitive promoter binding (GO:0010944)2.31203409
170COPII vesicle coating (GO:0048208)2.30287405
1713-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.29952713
172purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.29952713
173lung secretory cell differentiation (GO:0061140)2.29325005
174signal peptide processing (GO:0006465)2.29124566
175rRNA metabolic process (GO:0016072)2.28158727
176tight junction assembly (GO:0070830)2.27792919
177retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.27553337
178renal absorption (GO:0070293)2.27040419
179multicellular organismal water homeostasis (GO:0050891)2.25729663
180rRNA modification (GO:0000154)2.25559829
181signal transduction involved in regulation of gene expression (GO:0023019)2.23062298
182chaperone mediated protein folding requiring cofactor (GO:0051085)2.21162030
183positive regulation of gamma-delta T cell activation (GO:0046645)2.19532135
184phosphatidylserine acyl-chain remodeling (GO:0036150)2.19321078
185negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.18394946
186nucleotide-sugar metabolic process (GO:0009225)2.18191325
187purine deoxyribonucleotide catabolic process (GO:0009155)2.17513763
188telomere maintenance via semi-conservative replication (GO:0032201)2.17208207
189positive thymic T cell selection (GO:0045059)2.16737416
190innate immune response in mucosa (GO:0002227)2.16607067
191epithelial structure maintenance (GO:0010669)2.16600625

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.96931318
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.56696304
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.11666566
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.07401513
5E2F7_22180533_ChIP-Seq_HELA_Human2.61875614
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.27685075
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.21640521
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.14465716
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.10448549
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.09969782
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.01300812
12EST1_17652178_ChIP-ChIP_JURKAT_Human1.99715504
13XRN2_22483619_ChIP-Seq_HELA_Human1.98796379
14ETS1_20019798_ChIP-Seq_JURKAT_Human1.97172256
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.91280291
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.82327748
17TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.81525654
18ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.79197665
19ELF1_17652178_ChIP-ChIP_JURKAT_Human1.75936004
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75486850
21EGR1_19374776_ChIP-ChIP_THP-1_Human1.75146526
22NELFA_20434984_ChIP-Seq_ESCs_Mouse1.73770346
23TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.71831529
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.71206356
25SOX2_27498859_Chip-Seq_STOMACH_Mouse1.68383509
26VDR_23849224_ChIP-Seq_CD4+_Human1.67414244
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.67009938
28NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.64964412
29MYC_22102868_ChIP-Seq_BL_Human1.61554874
30CREB1_15753290_ChIP-ChIP_HEK293T_Human1.61432639
31DCP1A_22483619_ChIP-Seq_HELA_Human1.58008801
32STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.55843840
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.55041147
34KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.53827090
35KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.53827090
36KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.53827090
37VDR_21846776_ChIP-Seq_THP-1_Human1.47695735
38TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45556146
39GATA6_25053715_ChIP-Seq_YYC3_Human1.44957518
40HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.43721641
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.42711702
42HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.42530070
43RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41070542
44CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39923392
45FOXP3_21729870_ChIP-Seq_TREG_Human1.38454607
46NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.37711069
47IRF8_22096565_ChIP-ChIP_GC-B_Human1.37239848
48FOXM1_23109430_ChIP-Seq_U2OS_Human1.35562042
49GABP_19822575_ChIP-Seq_HepG2_Human1.33562616
50KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.33006554
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.32975290
52TTF2_22483619_ChIP-Seq_HELA_Human1.32670187
53AR_21909140_ChIP-Seq_LNCAP_Human1.30993693
54POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.27938409
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.27900007
56ELK1_22589737_ChIP-Seq_MCF10A_Human1.27225340
57NANOG_16153702_ChIP-ChIP_HESCs_Human1.27014589
58ELF5_23300383_ChIP-Seq_T47D_Human1.25270477
59ATF3_27146783_Chip-Seq_COLON_Human1.24879364
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.24727516
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.24525595
62STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.24342272
63* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24171780
64KDM5A_27292631_Chip-Seq_BREAST_Human1.23700868
65SRY_22984422_ChIP-ChIP_TESTIS_Rat1.23691863
66CHD1_26751641_Chip-Seq_LNCaP_Human1.23070730
67NANOG_18555785_ChIP-Seq_MESCs_Mouse1.22023731
68ZNF263_19887448_ChIP-Seq_K562_Human1.21297542
69ESR1_21235772_ChIP-Seq_MCF-7_Human1.21098550
70NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.20814653
71CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.20696126
72CIITA_25753668_ChIP-Seq_RAJI_Human1.19518170
73KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19278077
74FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.19098390
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.19067961
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.19023180
77GATA4_25053715_ChIP-Seq_YYC3_Human1.18739409
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.17234388
79FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.16623961
80KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16335440
81CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.16250864
82SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.14885850
83RACK7_27058665_Chip-Seq_MCF-7_Human1.13967321
84GATA3_24758297_ChIP-Seq_MCF-7_Human1.13539820
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13291774
86E2F4_17652178_ChIP-ChIP_JURKAT_Human1.13256999
87ERG_20887958_ChIP-Seq_HPC-7_Mouse1.12488905
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.12386099
89CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11981221
90PADI4_21655091_ChIP-ChIP_MCF-7_Human1.09936179
91FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07170417
92TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06672851
93SRF_21415370_ChIP-Seq_HL-1_Mouse1.06283489
94SOX2_18555785_ChIP-Seq_MESCs_Mouse1.05892365
95ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.05279345
96CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04521869
97PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04446654
98HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.03882682
99POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.03500269
100NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.03263782
101HOXB4_20404135_ChIP-ChIP_EML_Mouse1.01653590
102SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.01397635
103FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.01130145
104PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00138653
105FOXP1_21924763_ChIP-Seq_HESCs_Human1.00025669
106CDX2_20551321_ChIP-Seq_CACO-2_Human0.99538298
107DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99511045
108PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.99505346
109ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.99389630
110GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98729738
111E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.98446817
112SPI1_23547873_ChIP-Seq_NB4_Human0.98437404
113UTX_26944678_Chip-Seq_JUKART_Human0.98270447
114HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.98045929
115BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.97327118
116SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.96636149
117E2F1_21310950_ChIP-Seq_MCF-7_Human0.96606463
118MYCN_18555785_ChIP-Seq_MESCs_Mouse0.96199605
119ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.96114830
120CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95788082
121TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.95037041
122PPARA_22158963_ChIP-Seq_LIVER_Mouse0.94891058
123SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.94852975
124RXR_22158963_ChIP-Seq_LIVER_Mouse0.94702920
125MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.94560114
126* SOX2_20726797_ChIP-Seq_SW620_Human0.93526535
127POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.93502255
128TCF3_18692474_ChIP-Seq_MEFs_Mouse0.93337748
129MAF_26560356_Chip-Seq_TH1_Human0.92393100
130CTCF_26484167_Chip-Seq_Bcells_Mouse0.91761611
131ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91399696
132STAT4_19710469_ChIP-ChIP_TH1__Mouse0.91060302
133RBPJ_21746931_ChIP-Seq_IB4_Human0.90221713
134NANOG_18692474_ChIP-Seq_MEFs_Mouse0.89959962
135NANOG_20526341_ChIP-Seq_ESCs_Human0.89866132
136* PHF8_20622854_ChIP-Seq_HELA_Human0.88830009
137* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88539891
138SOX2_18692474_ChIP-Seq_MEFs_Mouse0.88405862
139ELK1_19687146_ChIP-ChIP_HELA_Human0.88377536

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.30327415
2MP0005410_abnormal_fertilization3.13382206
3MP0010234_abnormal_vibrissa_follicle2.84663237
4MP0004264_abnormal_extraembryonic_tissu2.75587898
5MP0001873_stomach_inflammation2.65301050
6MP0003283_abnormal_digestive_organ2.59571511
7MP0010352_gastrointestinal_tract_polyps2.48227295
8MP0003718_maternal_effect2.44183947
9MP0003866_abnormal_defecation2.33212423
10MP0000490_abnormal_crypts_of2.32986107
11MP0004957_abnormal_blastocyst_morpholog2.30531149
12MP0001666_abnormal_nutrient_absorption2.19379000
13MP0003806_abnormal_nucleotide_metabolis2.17562466
14MP0010155_abnormal_intestine_physiology2.09119725
15MP0009379_abnormal_foot_pigmentation2.08591821
16MP0003763_abnormal_thymus_physiology2.08095496
17MP0005365_abnormal_bile_salt2.01437887
18MP0000462_abnormal_digestive_system1.92897676
19MP0003300_gastrointestinal_ulcer1.92347504
20MP0003878_abnormal_ear_physiology1.81775905
21MP0005377_hearing/vestibular/ear_phenot1.81775905
22MP0002277_abnormal_respiratory_mucosa1.81328887
23MP0002139_abnormal_hepatobiliary_system1.79213321
24MP0001849_ear_inflammation1.72278676
25MP0003941_abnormal_skin_development1.61363068
26MP0005670_abnormal_white_adipose1.58830013
27MP0001188_hyperpigmentation1.58545459
28MP0006292_abnormal_olfactory_placode1.56602012
29MP0000477_abnormal_intestine_morphology1.53800922
30MP0005220_abnormal_exocrine_pancreas1.52831408
31MP0000678_abnormal_parathyroid_gland1.48788051
32MP0005332_abnormal_amino_acid1.43663254
33MP0002098_abnormal_vibrissa_morphology1.41883391
34MP0005085_abnormal_gallbladder_physiolo1.37576026
35MP0002138_abnormal_hepatobiliary_system1.37462282
36MP0008004_abnormal_stomach_pH1.37183333
37MP0008932_abnormal_embryonic_tissue1.37108826
38MP0002132_abnormal_respiratory_system1.36477912
39MP0004133_heterotaxia1.34621536
40MP0001485_abnormal_pinna_reflex1.33934821
41MP0005367_renal/urinary_system_phenotyp1.33287351
42MP0000516_abnormal_urinary_system1.33287351
43MP0002693_abnormal_pancreas_physiology1.33101140
44MP0009333_abnormal_splenocyte_physiolog1.32509207
45MP0000566_synostosis1.30778818
46MP0005381_digestive/alimentary_phenotyp1.29530041
47MP0003077_abnormal_cell_cycle1.28046739
48MP0001663_abnormal_digestive_system1.26858030
49MP0003453_abnormal_keratinocyte_physiol1.25573476
50MP0002396_abnormal_hematopoietic_system1.25271241
51MP0000613_abnormal_salivary_gland1.24724412
52MP0004947_skin_inflammation1.24453686
53MP0000470_abnormal_stomach_morphology1.23937462
54MP0001944_abnormal_pancreas_morphology1.23694796
55MP0009278_abnormal_bone_marrow1.22805827
56MP0003123_paternal_imprinting1.22075924
57MP0002796_impaired_skin_barrier1.21966677
58MP0009643_abnormal_urine_homeostasis1.21767270
59MP0005379_endocrine/exocrine_gland_phen1.19728822
60MP0006036_abnormal_mitochondrial_physio1.19567301
61MP0000537_abnormal_urethra_morphology1.18676505
62MP0001730_embryonic_growth_arrest1.18590493
63MP0001929_abnormal_gametogenesis1.18001578
64MP0005451_abnormal_body_composition1.17155003
65MP0000685_abnormal_immune_system1.16129446
66MP0002060_abnormal_skin_morphology1.15666913
67MP0008875_abnormal_xenobiotic_pharmacok1.15363272
68MP0002877_abnormal_melanocyte_morpholog1.14631778
69MP0000579_abnormal_nail_morphology1.14016791
70MP0002166_altered_tumor_susceptibility1.13990528
71MP0004043_abnormal_pH_regulation1.13877657
72MP0005076_abnormal_cell_differentiation1.13816316
73MP0003698_abnormal_male_reproductive1.13555284
74MP0003436_decreased_susceptibility_to1.12828096
75MP0002822_catalepsy1.11148913
76MP0004019_abnormal_vitamin_homeostasis1.09200553
77MP0001216_abnormal_epidermal_layer1.09081293
78MP0008058_abnormal_DNA_repair1.08791311
79MP0003724_increased_susceptibility_to1.08099797
80MP0001764_abnormal_homeostasis1.05816561
81MP0010030_abnormal_orbit_morphology1.05127849
82MP0005360_urolithiasis1.04767871
83MP0000467_abnormal_esophagus_morphology1.04615277
84MP0010678_abnormal_skin_adnexa1.04156695
85MP0006035_abnormal_mitochondrial_morpho1.03262080
86MP0002405_respiratory_system_inflammati1.02692447
87MP0003119_abnormal_digestive_system1.01046658
88MP0002163_abnormal_gland_morphology1.00919164
89MP0001881_abnormal_mammary_gland0.99610203
90MP0005501_abnormal_skin_physiology0.99189379
91MP0001765_abnormal_ion_homeostasis0.98788111
92MP0003786_premature_aging0.97257111
93MP0005395_other_phenotype0.96400337
94MP0005408_hypopigmentation0.96298691
95MP0002909_abnormal_adrenal_gland0.96226634
96MP0009672_abnormal_birth_weight0.96088698
97MP0010094_abnormal_chromosome_stability0.95132622
98MP0008872_abnormal_physiological_respon0.94784024
99MP0003111_abnormal_nucleus_morphology0.94522256
100MP0004782_abnormal_surfactant_physiolog0.94417491
101MP0005636_abnormal_mineral_homeostasis0.93653754
102MP0000350_abnormal_cell_proliferation0.93647064
103MP0005310_abnormal_salivary_gland0.89725161
104MP0008007_abnormal_cellular_replicative0.89646471
105MP0009697_abnormal_copulation0.88964872
106MP0001664_abnormal_digestion0.88791233
107MP0000465_gastrointestinal_hemorrhage0.88337790
108MP0003191_abnormal_cellular_cholesterol0.87806202
109MP0002085_abnormal_embryonic_tissue0.86867526
110MP0002111_abnormal_tail_morphology0.86833946
111MP0004381_abnormal_hair_follicle0.86245717
112MP0001145_abnormal_male_reproductive0.86203085
113MP0002006_tumorigenesis0.86125181
114MP0002084_abnormal_developmental_patter0.86085480
115MP0001845_abnormal_inflammatory_respons0.85913755
116MP0003011_delayed_dark_adaptation0.84758675
117MP0009785_altered_susceptibility_to0.84453376
118MP0002254_reproductive_system_inflammat0.83296038
119MP0003315_abnormal_perineum_morphology0.83221996
120MP0003183_abnormal_peptide_metabolism0.83142287
121MP0001293_anophthalmia0.82544907
122MP0001756_abnormal_urination0.82200718
123MP0001672_abnormal_embryogenesis/_devel0.82013339
124MP0005380_embryogenesis_phenotype0.82013339
125MP0000377_abnormal_hair_follicle0.81759822
126MP0003890_abnormal_embryonic-extraembry0.81608429
127MP0001697_abnormal_embryo_size0.81585539
128MP0009384_cardiac_valve_regurgitation0.81355955
129MP0002019_abnormal_tumor_incidence0.81226223
130MP0009840_abnormal_foam_cell0.80755366
131MP0003566_abnormal_cell_adhesion0.79955484
132MP0002420_abnormal_adaptive_immunity0.79759076
133MP0001819_abnormal_immune_cell0.79167505
134MP0005671_abnormal_response_to0.78957330
135MP0002210_abnormal_sex_determination0.78456819
136MP0002398_abnormal_bone_marrow0.78212656
137MP0003186_abnormal_redox_activity0.78089085
138MP0005397_hematopoietic_system_phenotyp0.77679325
139MP0001545_abnormal_hematopoietic_system0.77679325
140MP0005023_abnormal_wound_healing0.77348391
141MP0000858_altered_metastatic_potential0.77210609
142MP0002080_prenatal_lethality0.76815046
143MP0000703_abnormal_thymus_morphology0.76640098
144MP0002148_abnormal_hypersensitivity_rea0.76351278
145MP0002161_abnormal_fertility/fecundity0.76295213
146MP0000538_abnormal_urinary_bladder0.76164137
147MP0000313_abnormal_cell_death0.75209932
148MP0000627_abnormal_mammary_gland0.75088101
149MP0000653_abnormal_sex_gland0.72393610

Predicted human phenotypes

RankGene SetZ-score
1Chronic bronchitis (HP:0004469)3.68561370
2Abnormality of cells of the erythroid lineage (HP:0012130)3.65842123
3Reticulocytopenia (HP:0001896)3.57815626
4Milia (HP:0001056)3.54694252
5Onycholysis (HP:0001806)3.48122766
6Abnormal number of erythroid precursors (HP:0012131)3.32375120
7Right ventricular cardiomyopathy (HP:0011663)3.29814149
811 pairs of ribs (HP:0000878)3.26252954
9Fragile nails (HP:0001808)3.23282042
10Colon cancer (HP:0003003)3.21273123
11Pustule (HP:0200039)3.05132289
12Late onset (HP:0003584)3.03274341
13Abnormal hemoglobin (HP:0011902)3.03052089
14Microretrognathia (HP:0000308)2.99618313
15Severe visual impairment (HP:0001141)2.99614360
16Hyperglycinuria (HP:0003108)2.90802910
17Acute encephalopathy (HP:0006846)2.84711928
18Azoospermia (HP:0000027)2.81305585
19Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.80565577
20Pili torti (HP:0003777)2.80530466
21Biliary tract neoplasm (HP:0100574)2.79151762
22Rough bone trabeculation (HP:0100670)2.75707719
23Abnormal biliary tract morphology (HP:0012440)2.74487042
24Trismus (HP:0000211)2.73135341
25Abdominal distention (HP:0003270)2.61516541
26Abnormal pancreas size (HP:0012094)2.61292695
27Micronodular cirrhosis (HP:0001413)2.60142819
28Intrahepatic cholestasis (HP:0001406)2.57939505
29Acute necrotizing encephalopathy (HP:0006965)2.56210768
30Amelogenesis imperfecta (HP:0000705)2.55286403
31Male infertility (HP:0003251)2.53873941
32Villous atrophy (HP:0011473)2.49747600
33Abnormality of small intestinal villus morphology (HP:0011472)2.49747600
34Megaloblastic anemia (HP:0001889)2.46663311
35Abnormality of glycine metabolism (HP:0010895)2.45893384
36Abnormality of serine family amino acid metabolism (HP:0010894)2.45893384
37Hypoglycemic coma (HP:0001325)2.44878233
38Aplasia/Hypoplasia of the sacrum (HP:0008517)2.44204020
39Hyperactive renin-angiotensin system (HP:0000841)2.39568611
40Aplastic anemia (HP:0001915)2.38716840
41Hepatocellular necrosis (HP:0001404)2.38365823
42Macrocytic anemia (HP:0001972)2.37831274
43Abnormality of vitamin B metabolism (HP:0004340)2.34348862
44Abnormal mitochondria in muscle tissue (HP:0008316)2.34119229
45Woolly hair (HP:0002224)2.33831542
46Generalized aminoaciduria (HP:0002909)2.30372252
47Oral leukoplakia (HP:0002745)2.30275710
48Abnormality of aspartate family amino acid metabolism (HP:0010899)2.29892703
49Abnormal spermatogenesis (HP:0008669)2.29421145
50Cerebral edema (HP:0002181)2.27555329
51Rectal prolapse (HP:0002035)2.27103515
52Cheilitis (HP:0100825)2.27080848
53Decreased circulating renin level (HP:0003351)2.26389331
54Mitochondrial inheritance (HP:0001427)2.25505341
55Pallor (HP:0000980)2.24950330
56Methylmalonic aciduria (HP:0012120)2.24073459
57Aplasia/hypoplasia of the uterus (HP:0008684)2.23512292
58Abnormal respiratory motile cilium physiology (HP:0012261)2.23197343
59Increased CSF lactate (HP:0002490)2.22351019
60Hypoplasia of the uterus (HP:0000013)2.21605091
61Abnormality of vitamin metabolism (HP:0100508)2.21162753
62Abnormality of glutamine family amino acid metabolism (HP:0010902)2.21065350
63Gout (HP:0001997)2.20237770
64Symptomatic seizures (HP:0011145)2.20088910
65Abnormality of the vitamin B12 metabolism (HP:0004341)2.19923923
66Abnormality of the gastric mucosa (HP:0004295)2.18471737
67Congenital malformation of the right heart (HP:0011723)2.18250617
68Double outlet right ventricle (HP:0001719)2.18250617
69Rhinitis (HP:0012384)2.17182250
70Bronchiectasis (HP:0002110)2.16253162
71Abnormality of sulfur amino acid metabolism (HP:0004339)2.13552705
72Increased purine levels (HP:0004368)2.13466943
73Hyperuricemia (HP:0002149)2.13466943
74Increased hepatocellular lipid droplets (HP:0006565)2.12842286
75Plantar hyperkeratosis (HP:0007556)2.12637059
76Exocrine pancreatic insufficiency (HP:0001738)2.12277058
77Lipid accumulation in hepatocytes (HP:0006561)2.12178847
78Abnormal trabecular bone morphology (HP:0100671)2.11775091
79Hyponatremia (HP:0002902)2.11644804
80Thrombocytosis (HP:0001894)2.11391516
81Lethargy (HP:0001254)2.09971029
82Ileus (HP:0002595)2.09025659
83Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.08926860
84Renal salt wasting (HP:0000127)2.08738481
85Abnormal respiratory motile cilium morphology (HP:0005938)2.08609553
86Abnormal respiratory epithelium morphology (HP:0012253)2.08609553
87Abnormality of serum amino acid levels (HP:0003112)2.07968474
88Abnormality of methionine metabolism (HP:0010901)2.07549177
89Neoplasm of the pancreas (HP:0002894)2.04937280
90Hyperparathyroidism (HP:0000843)2.04250887
91Median cleft lip (HP:0000161)2.03292011
92Abnormality of monocarboxylic acid metabolism (HP:0010996)2.01794623
93Progressive macrocephaly (HP:0004481)1.99942440
94Vertebral hypoplasia (HP:0008417)1.99745404
95Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.99745404
96Hepatic necrosis (HP:0002605)1.99374252
97Malnutrition (HP:0004395)1.98920434
98Hyperglycinemia (HP:0002154)1.98648571
99Abnormality of renin-angiotensin system (HP:0000847)1.98417314
100Renal Fanconi syndrome (HP:0001994)1.98285381
101Abnormality of chloride homeostasis (HP:0011422)1.97981435
102Neoplasm of the rectum (HP:0100743)1.97603822
103Hyperphosphatemia (HP:0002905)1.96289043
104Abnormality of the 1st metacarpal (HP:0010009)1.96206843
105Unilateral renal agenesis (HP:0000122)1.96034312
106Hypoplasia of the radius (HP:0002984)1.95927227
107Neoplasm of the colon (HP:0100273)1.95580323
108Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94132221
109Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94132221
110IgM deficiency (HP:0002850)1.93550203
111Abnormality of aromatic amino acid family metabolism (HP:0004338)1.93449458
112Palpitations (HP:0001962)1.91865920
113Methylmalonic acidemia (HP:0002912)1.91467965
114Septo-optic dysplasia (HP:0100842)1.91444877
115T lymphocytopenia (HP:0005403)1.91422674
116Abnormality of the labia minora (HP:0012880)1.90298785
117Missing ribs (HP:0000921)1.89891757
118Prolonged partial thromboplastin time (HP:0003645)1.89793685
119Flat acetabular roof (HP:0003180)1.89510059
120Uterine neoplasm (HP:0010784)1.89118558
121Insulin resistance (HP:0000855)1.88748040
122Periodontitis (HP:0000704)1.87891860
123Abnormality of urine glucose concentration (HP:0011016)1.86940092
124Glycosuria (HP:0003076)1.86940092
125Infertility (HP:0000789)1.86079061
126Abnormal blistering of the skin (HP:0008066)1.85842601
127Maternal diabetes (HP:0009800)1.85642024
128Abnormality of renal resorption (HP:0011038)1.84821227
129Abnormal protein glycosylation (HP:0012346)1.83412098
130Abnormal glycosylation (HP:0012345)1.83412098
131Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.83412098
132Abnormal protein N-linked glycosylation (HP:0012347)1.83412098
133Hypoglycemic seizures (HP:0002173)1.81954559
134Type I transferrin isoform profile (HP:0003642)1.81855624
135Absent/shortened dynein arms (HP:0200106)1.80882728
136Dynein arm defect of respiratory motile cilia (HP:0012255)1.80882728
137Abnormal ciliary motility (HP:0012262)1.80725902
138Autoimmune hemolytic anemia (HP:0001890)1.80261756
139Premature loss of primary teeth (HP:0006323)1.78406727
140Abnormality of endocrine pancreas physiology (HP:0012093)1.78381123
141Abnormality of the pancreatic islet cells (HP:0006476)1.78381123
142Hyperphosphaturia (HP:0003109)1.77069664
143Breast carcinoma (HP:0003002)1.76861092
144Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.76848571
145Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.76761278
146Atrophic scars (HP:0001075)1.76329143
147Facial cleft (HP:0002006)1.75745952
148Nail dystrophy (HP:0008404)1.75291286
149Carpal bone hypoplasia (HP:0001498)1.74647487
150Abnormality of T cell number (HP:0011839)1.74185117
151Vacuolated lymphocytes (HP:0001922)1.73527547
152Neoplasm of the adrenal gland (HP:0100631)1.73148063
153Hyperglycemia (HP:0003074)1.72775550
154Ureteral stenosis (HP:0000071)1.72658849
155Hyperinsulinemic hypoglycemia (HP:0000825)1.72466654
156Abnormal hair laboratory examination (HP:0003328)1.72418980
157Poikiloderma (HP:0001029)1.72198652
158Neoplasm of the small intestine (HP:0100833)1.72190728
159Testicular atrophy (HP:0000029)1.71168164
160Increased serum lactate (HP:0002151)1.70955886
161Pancreatic islet-cell hyperplasia (HP:0004510)1.70423009
162Exertional dyspnea (HP:0002875)1.70322451
163Ridged nail (HP:0001807)1.70313330
164Abdominal situs inversus (HP:0003363)1.69986094
165Abnormality of abdominal situs (HP:0011620)1.69986094
166Sparse eyelashes (HP:0000653)1.69392825
167Confusion (HP:0001289)1.69263835
168Hyperaldosteronism (HP:0000859)1.69220694
169Abnormality of the anterior horn cell (HP:0006802)1.69200185
170Degeneration of anterior horn cells (HP:0002398)1.69200185
171Abnormality of T cells (HP:0002843)1.69048232
172Fat malabsorption (HP:0002630)1.68949866
173Dicarboxylic aciduria (HP:0003215)1.68789730
174Multiple enchondromatosis (HP:0005701)1.67004930

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R3.64327535
2PBK3.61570411
3EPHA23.44483756
4ERN12.95241292
5VRK22.72652247
6MAP3K102.71675396
7MST42.69554501
8NME22.35376496
9MAPK152.35084426
10MAP2K22.18930489
11RPS6KB22.15031357
12FRK2.08464705
13NME12.07515662
14TNIK2.00563440
15IRAK31.91789493
16TESK11.80160297
17ZAP701.76972976
18PASK1.70132301
19STK161.68669491
20KDR1.68471064
21MAP4K11.64408706
22TRIM281.63456315
23MAP3K31.61349657
24STK391.60002073
25RPS6KA41.57708865
26TAF11.55280460
27LRRK21.54877689
28CDC71.51385953
29STK101.49951353
30NLK1.48505726
31MAP3K21.45821218
32MAP3K111.45191543
33TSSK61.43424794
34BCKDK1.41670734
35MKNK21.35728830
36BMPR1B1.35530900
37BUB11.33555041
38DYRK31.31041984
39PAK41.30689617
40MAP2K61.29928127
41PTK61.27562920
42PRKCI1.27053971
43MAPKAPK31.26966728
44PRKD31.24646057
45INSRR1.22225850
46SMG11.21288103
47STK241.20660718
48PLK31.18720955
49OXSR11.16469555
50PDK21.13009236
51TYK21.12885233
52NEK21.12834716
53STK38L1.08778321
54AURKB1.07185365
55PKN21.05903128
56FER1.05892082
57TEC0.98047809
58NEK10.97610502
59BRSK20.97562050
60MET0.96915227
61PRKG20.95714479
62LMTK20.95522864
63MAP3K80.95299388
64TAOK30.92651560
65WNK40.92188442
66TESK20.91795844
67DYRK1B0.90944562
68BTK0.90826666
69NUAK10.90724852
70PIM20.90722945
71EEF2K0.89508060
72HIPK20.88694654
73CHUK0.87989569
74ITK0.82536046
75PTK20.82427477
76EIF2AK30.81866771
77STK30.81227294
78SCYL20.80279181
79FGFR40.80251736
80IKBKE0.80106324
81WEE10.79289089
82GRK60.78564811
83TTK0.75583193
84TLK10.74359277
85MAP3K90.72893925
86JAK30.72404673
87FLT30.70405189
88TBK10.67386499
89CSK0.66022264
90PIK3CA0.65984666
91DAPK10.65312204
92MKNK10.65050825
93ACVR1B0.64505358
94STK40.63692565
95TRIB30.62514246
96SIK10.62048706
97ABL20.61717238
98CDK70.61186634
99MYLK0.60907981
100MAP3K120.60737236
101RIPK10.58321392
102SRPK10.58220324
103PLK10.56963770
104BLK0.55382524
105ZAK0.53471450
106VRK10.51934717
107MAP4K20.50985683
108CDK90.49705720
109ILK0.49616942
110PNCK0.47417383
111BRSK10.47357130
112MAPKAPK20.47093884
113PLK40.45214454
114TAOK10.44875990
115FGFR20.44648316
116MAP2K10.44647974
117LATS10.44131373
118ERBB40.44097059
119PDK40.43986143
120PDK30.43986143
121FGFR10.43268256
122MAP2K30.43156716
123TXK0.41657701
124IKBKB0.41086136
125CSNK2A10.40147061
126STK380.40108288
127DDR20.39484704
128PRKCE0.39411836
129EIF2AK10.39217876
130CHEK20.39086388
131SIK30.38745823
132PIK3CG0.38698889
133GRK10.38223024
134LCK0.38132589
135CAMK2D0.38132197
136LATS20.38058829
137CDK120.37218599
138IRAK40.36664256
139CHEK10.36440591
140CSNK1E0.36010583
141NEK60.35883603
142WNK30.35873397
143CSNK1G10.34781937
144CSNK2A20.34651234
145ALK0.32722309
146DYRK20.32655488
147MUSK0.31679205
148CSNK1A10.29258739
149ATM0.25941217

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.27822525
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.86024034
3Sulfur metabolism_Homo sapiens_hsa009203.73063317
4Protein export_Homo sapiens_hsa030602.64615070
5Sulfur relay system_Homo sapiens_hsa041222.57811130
6Vitamin digestion and absorption_Homo sapiens_hsa049772.50661100
7RNA polymerase_Homo sapiens_hsa030202.17331940
8DNA replication_Homo sapiens_hsa030302.06554407
9Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.98032084
102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.96132879
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.92590554
12Mismatch repair_Homo sapiens_hsa034301.85802639
13Proteasome_Homo sapiens_hsa030501.81808240
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.76264874
15Pyrimidine metabolism_Homo sapiens_hsa002401.76209285
16Folate biosynthesis_Homo sapiens_hsa007901.71298542
17Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.68511471
18Homologous recombination_Homo sapiens_hsa034401.66779887
19Pyruvate metabolism_Homo sapiens_hsa006201.66134629
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.66048791
21Spliceosome_Homo sapiens_hsa030401.60805757
22Vitamin B6 metabolism_Homo sapiens_hsa007501.57366384
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.56025245
24Base excision repair_Homo sapiens_hsa034101.55799450
25Fatty acid elongation_Homo sapiens_hsa000621.48246715
26Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.47804732
27Galactose metabolism_Homo sapiens_hsa000521.42495490
28Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.41336618
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.40784830
30Phenylalanine metabolism_Homo sapiens_hsa003601.40448516
31Retinol metabolism_Homo sapiens_hsa008301.39969144
32Fat digestion and absorption_Homo sapiens_hsa049751.38606544
33Pentose and glucuronate interconversions_Homo sapiens_hsa000401.38414834
34Arginine and proline metabolism_Homo sapiens_hsa003301.37330846
35Propanoate metabolism_Homo sapiens_hsa006401.35552108
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.33118345
37Arginine biosynthesis_Homo sapiens_hsa002201.32374201
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.29301371
39Fructose and mannose metabolism_Homo sapiens_hsa000511.26843354
40RNA transport_Homo sapiens_hsa030131.25801665
41N-Glycan biosynthesis_Homo sapiens_hsa005101.25568003
42Primary immunodeficiency_Homo sapiens_hsa053401.24636909
43Thyroid cancer_Homo sapiens_hsa052161.23477162
44Biosynthesis of amino acids_Homo sapiens_hsa012301.19182006
45Selenocompound metabolism_Homo sapiens_hsa004501.12802937
46RNA degradation_Homo sapiens_hsa030181.12141717
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.11201793
48Antigen processing and presentation_Homo sapiens_hsa046121.10658886
49Pentose phosphate pathway_Homo sapiens_hsa000301.08618444
50Fatty acid metabolism_Homo sapiens_hsa012121.07401344
51Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.06703870
52Glutathione metabolism_Homo sapiens_hsa004801.06425492
53Drug metabolism - other enzymes_Homo sapiens_hsa009831.05343675
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.04455634
55Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.04041783
56Steroid biosynthesis_Homo sapiens_hsa001001.03068047
57p53 signaling pathway_Homo sapiens_hsa041151.02521849
58Peroxisome_Homo sapiens_hsa041461.02438951
59Oxidative phosphorylation_Homo sapiens_hsa001901.02359477
60beta-Alanine metabolism_Homo sapiens_hsa004101.00833505
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.00378145
62Nucleotide excision repair_Homo sapiens_hsa034200.99765289
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98722369
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.98190246
65Tyrosine metabolism_Homo sapiens_hsa003500.96641855
66Tryptophan metabolism_Homo sapiens_hsa003800.95611847
67Mineral absorption_Homo sapiens_hsa049780.94889732
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94032876
69Fatty acid biosynthesis_Homo sapiens_hsa000610.93794030
70Linoleic acid metabolism_Homo sapiens_hsa005910.93686935
71Other glycan degradation_Homo sapiens_hsa005110.89382996
72Legionellosis_Homo sapiens_hsa051340.89156799
73Caffeine metabolism_Homo sapiens_hsa002320.89111334
74Parkinsons disease_Homo sapiens_hsa050120.86944411
75Non-homologous end-joining_Homo sapiens_hsa034500.86269455
76Leukocyte transendothelial migration_Homo sapiens_hsa046700.85668028
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85234545
78Butanoate metabolism_Homo sapiens_hsa006500.84788882
79Cell cycle_Homo sapiens_hsa041100.80338909
80Intestinal immune network for IgA production_Homo sapiens_hsa046720.79864086
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79537762
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.78446813
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.77796252
84Hepatitis C_Homo sapiens_hsa051600.76604324
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76425127
86Bladder cancer_Homo sapiens_hsa052190.75766270
87Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.75216555
88Huntingtons disease_Homo sapiens_hsa050160.74714251
89Basal transcription factors_Homo sapiens_hsa030220.73252297
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.72968496
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72204336
92Purine metabolism_Homo sapiens_hsa002300.71654882
93Arachidonic acid metabolism_Homo sapiens_hsa005900.70316352
94Herpes simplex infection_Homo sapiens_hsa051680.66895499
95NF-kappa B signaling pathway_Homo sapiens_hsa040640.66337899
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.65626333
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65107011
98Chemical carcinogenesis_Homo sapiens_hsa052040.64929066
99Tight junction_Homo sapiens_hsa045300.64011240
100Influenza A_Homo sapiens_hsa051640.63093321
101NOD-like receptor signaling pathway_Homo sapiens_hsa046210.63019824
102One carbon pool by folate_Homo sapiens_hsa006700.61635011
103Glycerophospholipid metabolism_Homo sapiens_hsa005640.61108032
104Epstein-Barr virus infection_Homo sapiens_hsa051690.59102578
105Fanconi anemia pathway_Homo sapiens_hsa034600.58619605
106Small cell lung cancer_Homo sapiens_hsa052220.57943202
107T cell receptor signaling pathway_Homo sapiens_hsa046600.57367113
108mRNA surveillance pathway_Homo sapiens_hsa030150.57343530
109Histidine metabolism_Homo sapiens_hsa003400.56027667
110Starch and sucrose metabolism_Homo sapiens_hsa005000.53531344
111Protein digestion and absorption_Homo sapiens_hsa049740.52738747
112Sphingolipid metabolism_Homo sapiens_hsa006000.50682302
113Ether lipid metabolism_Homo sapiens_hsa005650.50549385
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50227589
115Alzheimers disease_Homo sapiens_hsa050100.49589184
116Measles_Homo sapiens_hsa051620.49310055
117Hematopoietic cell lineage_Homo sapiens_hsa046400.48603892
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48111323
119Prolactin signaling pathway_Homo sapiens_hsa049170.47081446
120Toxoplasmosis_Homo sapiens_hsa051450.46838360
121Apoptosis_Homo sapiens_hsa042100.46609229
122Pancreatic secretion_Homo sapiens_hsa049720.45853816
123Glycerolipid metabolism_Homo sapiens_hsa005610.45118514
124RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.44062045
125Acute myeloid leukemia_Homo sapiens_hsa052210.43534907
126Adherens junction_Homo sapiens_hsa045200.42228259
127Leishmaniasis_Homo sapiens_hsa051400.41802156
128Renin-angiotensin system_Homo sapiens_hsa046140.41084943
129HTLV-I infection_Homo sapiens_hsa051660.39489737
130Shigellosis_Homo sapiens_hsa051310.36590407
131Metabolic pathways_Homo sapiens_hsa011000.36472025
132Notch signaling pathway_Homo sapiens_hsa043300.35336127
133Fatty acid degradation_Homo sapiens_hsa000710.35175302
134TNF signaling pathway_Homo sapiens_hsa046680.34774362
135Transcriptional misregulation in cancer_Homo sapiens_hsa052020.31636323
136Carbon metabolism_Homo sapiens_hsa012000.30873087

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