L3MBTL4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1dopamine transport (GO:0015872)9.16513512
2peristalsis (GO:0030432)9.01121432
3phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)8.38265698
4regulation of dopamine uptake involved in synaptic transmission (GO:0051584)8.29443432
5regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)8.29443432
6piRNA metabolic process (GO:0034587)6.79354589
7cell proliferation in forebrain (GO:0021846)6.53877488
8adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)6.43096644
9lens fiber cell development (GO:0070307)6.41528367
10phenol-containing compound catabolic process (GO:0019336)6.38875747
11prepulse inhibition (GO:0060134)6.33012898
12behavioral response to cocaine (GO:0048148)6.19450087
13phasic smooth muscle contraction (GO:0014821)6.19030532
14synaptic transmission, dopaminergic (GO:0001963)6.15809195
15regulation of neurotransmitter uptake (GO:0051580)6.11853886
16astrocyte development (GO:0014002)6.11749602
17parental behavior (GO:0060746)6.10830187
18cerebellar granule cell differentiation (GO:0021707)6.03446584
19striatum development (GO:0021756)5.88160115
20transmission of nerve impulse (GO:0019226)5.62171917
21negative regulation of cAMP-mediated signaling (GO:0043951)5.53651089
22adult walking behavior (GO:0007628)5.32807167
23DNA methylation involved in gamete generation (GO:0043046)5.23408793
24sympathetic nervous system development (GO:0048485)5.19908222
25cell migration in hindbrain (GO:0021535)5.18333577
26synaptonemal complex organization (GO:0070193)4.97844040
27acrosome reaction (GO:0007340)4.95932084
28regulation of meiosis I (GO:0060631)4.71811644
29detection of temperature stimulus involved in sensory perception (GO:0050961)4.70290333
30detection of temperature stimulus involved in sensory perception of pain (GO:0050965)4.70290333
31neurofilament cytoskeleton organization (GO:0060052)4.66957113
32stem cell development (GO:0048864)4.62767834
33dentate gyrus development (GO:0021542)4.55829695
34detection of temperature stimulus (GO:0016048)4.54908329
35positive regulation of synapse assembly (GO:0051965)4.54196757
36acrosome assembly (GO:0001675)4.52467529
37regulation of catecholamine metabolic process (GO:0042069)4.52197923
38regulation of dopamine metabolic process (GO:0042053)4.52197923
39male meiosis (GO:0007140)4.50704467
40regulation of synaptic transmission, dopaminergic (GO:0032225)4.50352783
41long term synaptic depression (GO:0060292)4.50266674
42sex differentiation (GO:0007548)4.48797307
43fusion of sperm to egg plasma membrane (GO:0007342)4.48605244
44grooming behavior (GO:0007625)4.47774713
45behavioral response to ethanol (GO:0048149)4.42593362
46behavioral response to nicotine (GO:0035095)4.39485689
47synaptonemal complex assembly (GO:0007130)4.38666128
48maturation of 5.8S rRNA (GO:0000460)4.38352124
49asymmetric protein localization (GO:0008105)4.33086709
50sperm motility (GO:0030317)4.27889083
51positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-4.23087888
52cilium or flagellum-dependent cell motility (GO:0001539)4.11323007
53nephron epithelium morphogenesis (GO:0072088)4.08342353
54nephron tubule morphogenesis (GO:0072078)4.08342353
55positive regulation of synaptic transmission, glutamatergic (GO:0051968)4.07394666
56somatic stem cell division (GO:0048103)4.04446810
57positive regulation of cAMP-mediated signaling (GO:0043950)4.04207828
58negative regulation of oligodendrocyte differentiation (GO:0048715)4.01499539
59positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.98124006
60neuron fate determination (GO:0048664)3.96325826
61neuron cell-cell adhesion (GO:0007158)3.94751564
62negative regulation of dendrite morphogenesis (GO:0050774)3.92946486
63positive regulation of potassium ion transport (GO:0043268)3.92071057
64neuronal stem cell maintenance (GO:0097150)3.87768664
65calcium ion-dependent exocytosis (GO:0017156)3.86546421
66monoamine transport (GO:0015844)3.85417383
67vasodilation (GO:0042311)3.83150858
68protein localization to synapse (GO:0035418)3.77168568
69response to amphetamine (GO:0001975)3.72064867
70regulation of NFAT protein import into nucleus (GO:0051532)3.71243283
71negative regulation of microtubule polymerization (GO:0031115)3.70305416
72neuronal action potential propagation (GO:0019227)3.65723431
73vocalization behavior (GO:0071625)3.64768205
74cochlea development (GO:0090102)3.62998931
75cell morphogenesis involved in neuron differentiation (GO:0048667)3.58760794
76synaptic vesicle exocytosis (GO:0016079)3.56753266
77regulation of short-term neuronal synaptic plasticity (GO:0048172)3.56409262
78auditory receptor cell stereocilium organization (GO:0060088)3.55608174
79positive regulation of release of sequestered calcium ion into cytosol (GO:0051281)3.53467406
80epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.52693539
81fatty acid elongation (GO:0030497)3.50854356
82dopamine metabolic process (GO:0042417)3.47803671
83plasma membrane fusion (GO:0045026)3.45784942
84catecholamine transport (GO:0051937)3.44617930
85motile cilium assembly (GO:0044458)3.41321876
86positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.40692878
87behavioral fear response (GO:0001662)3.39395411
88behavioral defense response (GO:0002209)3.39395411
89dopamine biosynthetic process (GO:0042416)3.38982985
90artery development (GO:0060840)3.38944718
91regulation of cardioblast proliferation (GO:0003264)3.38161559
92regulation of secondary heart field cardioblast proliferation (GO:0003266)3.38161559
93neurotransmitter catabolic process (GO:0042135)3.37683760
94indole-containing compound catabolic process (GO:0042436)3.37398427
95indolalkylamine catabolic process (GO:0046218)3.37398427
96tryptophan catabolic process (GO:0006569)3.37398427
97neuron recognition (GO:0008038)3.31287379
98response to pain (GO:0048265)3.26773466
99regulation of synapse assembly (GO:0051963)3.25025580
100protein polyglutamylation (GO:0018095)3.24551017
101regulation of vesicle fusion (GO:0031338)3.23613251
102cysteine metabolic process (GO:0006534)3.23183625
103glutamate secretion (GO:0014047)3.22572506
104proline transport (GO:0015824)3.22258897
105ephrin receptor signaling pathway (GO:0048013)3.21248201
106positive regulation of meiosis (GO:0045836)3.18304748
107cerebellar Purkinje cell differentiation (GO:0021702)3.18110631
108synaptic transmission, cholinergic (GO:0007271)3.17605836
109positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.16909473
110radial glial cell differentiation (GO:0060019)3.16852009
111regulation of timing of cell differentiation (GO:0048505)3.16373388
112spermatid development (GO:0007286)3.15080232
113catechol-containing compound biosynthetic process (GO:0009713)3.14642647
114catecholamine biosynthetic process (GO:0042423)3.14642647
115multicellular organism reproduction (GO:0032504)3.14003480
116neurotransmitter secretion (GO:0007269)3.13693596
117presynaptic membrane organization (GO:0097090)3.13343446
118regulation of synaptic vesicle exocytosis (GO:2000300)3.12930423
119neuronal action potential (GO:0019228)3.12454666
120male meiosis I (GO:0007141)3.11741524
121multicellular organismal reproductive behavior (GO:0033057)3.10899109
122negative regulation of leukocyte chemotaxis (GO:0002689)3.08654945
123synaptic vesicle maturation (GO:0016188)3.08572427
124membrane depolarization during action potential (GO:0086010)3.08517091
125sodium-independent organic anion transport (GO:0043252)3.07990876
126detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.06112514
127pyrimidine nucleobase catabolic process (GO:0006208)3.05991027
128positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.01957579
129temperature homeostasis (GO:0001659)3.00680091
130negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.99321412
131response to water (GO:0009415)2.99191920
132calcium-mediated signaling using intracellular calcium source (GO:0035584)2.99093268
133nucleobase catabolic process (GO:0046113)2.97743435
134sperm-egg recognition (GO:0035036)2.97457928
135axonemal dynein complex assembly (GO:0070286)2.97367667
136neural tube formation (GO:0001841)2.97086474
137stem cell division (GO:0017145)2.95592827
138ganglion development (GO:0061548)2.94978320
139renal tubule morphogenesis (GO:0061333)2.94447700
140neuromuscular synaptic transmission (GO:0007274)2.94014719
141fear response (GO:0042596)2.93821347
142epithelial cell differentiation involved in kidney development (GO:0035850)2.93666623
143neural precursor cell proliferation (GO:0061351)2.93459738
144establishment of mitochondrion localization (GO:0051654)2.92795873
145enteric nervous system development (GO:0048484)2.92307915
146regulation of cAMP-dependent protein kinase activity (GO:2000479)2.91768581
147positive regulation of meiotic cell cycle (GO:0051446)2.91489137
148positive regulation of astrocyte differentiation (GO:0048711)2.91180876
149parturition (GO:0007567)2.90661685
150epithelial cilium movement (GO:0003351)2.88093922
151serine family amino acid catabolic process (GO:0009071)2.87765618
152positive regulation of neurotransmitter transport (GO:0051590)2.86631114
153binding of sperm to zona pellucida (GO:0007339)2.86108817
154positive regulation of potassium ion transmembrane transport (GO:1901381)2.86004149
155meiotic nuclear division (GO:0007126)2.85711473
156cilium movement (GO:0003341)2.84829637
157negative regulation of inclusion body assembly (GO:0090084)2.84641877
158activation of adenylate cyclase activity (GO:0007190)2.84296214
159cellular response to catecholamine stimulus (GO:0071870)2.83096649
160cellular response to monoamine stimulus (GO:0071868)2.83096649
161negative regulation of dendrite development (GO:2000171)2.83072492
162exploration behavior (GO:0035640)2.82903929
163mating behavior (GO:0007617)2.82809973
164embryonic axis specification (GO:0000578)2.82470494
165negative regulation of epidermal cell differentiation (GO:0045605)2.81226428
166cell aggregation (GO:0098743)2.80856536
167cartilage condensation (GO:0001502)2.80856536
168negative regulation of synaptic transmission, GABAergic (GO:0032229)2.80636335
169cell differentiation in hindbrain (GO:0021533)2.80442046
170regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.79904000
171smooth muscle contraction (GO:0006939)2.79362310
172neurotransmitter transport (GO:0006836)2.78364910
173adult locomotory behavior (GO:0008344)2.78312579
174inner ear receptor stereocilium organization (GO:0060122)2.77851079
175regulation of heat generation (GO:0031650)2.76299961
176axon extension (GO:0048675)2.75359483
177multicellular organismal signaling (GO:0035637)2.74349691
178regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.74146008
179nerve growth factor signaling pathway (GO:0038180)2.73493116
180high-density lipoprotein particle remodeling (GO:0034375)2.72333617
181regulation of neurotransmitter secretion (GO:0046928)2.71730442
182cell wall macromolecule catabolic process (GO:0016998)2.70838031
183cell wall macromolecule metabolic process (GO:0044036)2.70838031
184establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.69483602
185mitochondrion transport along microtubule (GO:0047497)2.69483602
186protein localization to cilium (GO:0061512)2.69219090
187layer formation in cerebral cortex (GO:0021819)2.68607794
188axon cargo transport (GO:0008088)2.67729861
189chromosome organization involved in meiosis (GO:0070192)2.67572516
190positive regulation of protein complex disassembly (GO:0043243)2.66153552
191regulation of synaptic vesicle transport (GO:1902803)2.65952629
192innervation (GO:0060384)2.65947764
193maternal behavior (GO:0042711)2.65649052
194substrate-independent telencephalic tangential migration (GO:0021826)10.0140520
195substrate-independent telencephalic tangential interneuron migration (GO:0021843)10.0140520

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.06017415
2GBX2_23144817_ChIP-Seq_PC3_Human3.32820671
3TAF15_26573619_Chip-Seq_HEK293_Human2.49815551
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.47348052
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.43804040
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.43740771
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.39584830
8ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse2.33755121
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.23762800
10* REST_21632747_ChIP-Seq_MESCs_Mouse2.19377345
11BMI1_23680149_ChIP-Seq_NPCS_Mouse2.18413806
12TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.17490920
13* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.13863487
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.13754324
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.09371438
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.06004974
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.04855654
18EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04592448
19RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04592448
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.01410487
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.96284612
22* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.96277732
23ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94127347
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.94058708
25SUZ12_27294783_Chip-Seq_ESCs_Mouse1.87489449
26* EZH2_27294783_Chip-Seq_ESCs_Mouse1.82520872
27RNF2_27304074_Chip-Seq_ESCs_Mouse1.81330594
28CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81073960
29EED_16625203_ChIP-ChIP_MESCs_Mouse1.80095037
30ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.78478756
31SMAD4_21799915_ChIP-Seq_A2780_Human1.75687855
32NR3C1_23031785_ChIP-Seq_PC12_Mouse1.75537944
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.69685805
34FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.68996450
35RNF2_27304074_Chip-Seq_NSC_Mouse1.68495854
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.67295364
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.60518567
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60457775
39CDX2_19796622_ChIP-Seq_MESCs_Mouse1.59496404
40FLI1_27457419_Chip-Seq_LIVER_Mouse1.59007367
41* CBX2_27304074_Chip-Seq_ESCs_Mouse1.54049789
42ZNF274_21170338_ChIP-Seq_K562_Hela1.49400936
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47818763
44PCGF2_27294783_Chip-Seq_ESCs_Mouse1.46681707
45P300_19829295_ChIP-Seq_ESCs_Human1.45512910
46FUS_26573619_Chip-Seq_HEK293_Human1.42874173
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42320665
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.42130042
49VDR_22108803_ChIP-Seq_LS180_Human1.42065018
50ERG_21242973_ChIP-ChIP_JURKAT_Human1.41713029
51* PIAS1_25552417_ChIP-Seq_VCAP_Human1.39866297
52EWS_26573619_Chip-Seq_HEK293_Human1.39220201
53CBP_20019798_ChIP-Seq_JUKART_Human1.39132154
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39132154
55* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39120161
56* SMAD3_21741376_ChIP-Seq_EPCs_Human1.38869284
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36248535
58RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32624880
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.31301763
60EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30802374
61CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.28847554
62AHR_22903824_ChIP-Seq_MCF-7_Human1.28596917
63* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.28225218
64* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.27887967
65RUNX_20019798_ChIP-Seq_JUKART_Human1.27762681
66DROSHA_22980978_ChIP-Seq_HELA_Human1.27310752
67PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27275461
68BCAT_22108803_ChIP-Seq_LS180_Human1.27135093
69* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26317308
70EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.25352194
71OCT1_27270436_Chip-Seq_PROSTATE_Human1.24124154
72SOX2_19829295_ChIP-Seq_ESCs_Human1.23634403
73NANOG_19829295_ChIP-Seq_ESCs_Human1.23634403
74MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23336735
75NANOG_18555785_Chip-Seq_ESCs_Mouse1.23176071
76GATA1_26923725_Chip-Seq_HPCs_Mouse1.22973598
77MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.22443728
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21313638
79SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20321299
80IKZF1_21737484_ChIP-ChIP_HCT116_Human1.20268818
81* AR_25329375_ChIP-Seq_VCAP_Human1.19867902
82PRDM14_20953172_ChIP-Seq_ESCs_Human1.19188849
83ARNT_22903824_ChIP-Seq_MCF-7_Human1.18235165
84EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18166978
85KDM2B_26808549_Chip-Seq_REH_Human1.17768046
86* TCF4_23295773_ChIP-Seq_U87_Human1.17529660
87IGF1R_20145208_ChIP-Seq_DFB_Human1.16598714
88PCGF2_27294783_Chip-Seq_NPCs_Mouse1.15650620
89KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14098832
90FOXA1_27270436_Chip-Seq_PROSTATE_Human1.13787642
91FOXA1_25329375_ChIP-Seq_VCAP_Human1.13787642
92RARB_27405468_Chip-Seq_BRAIN_Mouse1.13713434
93SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12650740
94STAT6_21828071_ChIP-Seq_BEAS2B_Human1.11819474
95TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.11403562
96STAT3_23295773_ChIP-Seq_U87_Human1.10208712
97RING1B_27294783_Chip-Seq_ESCs_Mouse1.09667397
98POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09517357
99TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09517357
100OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09246085
101RXR_22108803_ChIP-Seq_LS180_Human1.08500988
102* RUNX2_22187159_ChIP-Seq_PCA_Human1.08347368
103CRX_20693478_ChIP-Seq_RETINA_Mouse1.08026995
104CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07966861
105E2F1_18555785_Chip-Seq_ESCs_Mouse1.07752712
106CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.06850123
107* SOX2_21211035_ChIP-Seq_LN229_Gbm1.06723261
108CMYC_18555785_Chip-Seq_ESCs_Mouse1.06057154
109EZH2_27294783_Chip-Seq_NPCs_Mouse1.04905514
110BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.04873787
111CDX2_22108803_ChIP-Seq_LS180_Human1.04332340
112TP63_17297297_ChIP-ChIP_HaCaT_Human1.04229327
113NFE2_27457419_Chip-Seq_LIVER_Mouse1.03587160
114P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03048275
115* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02884979
116E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02878314
117ER_23166858_ChIP-Seq_MCF-7_Human1.02609877
118SMAD4_21741376_ChIP-Seq_EPCs_Human1.02572597
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.01623018
120P53_22387025_ChIP-Seq_ESCs_Mouse1.01028916
121TP53_18474530_ChIP-ChIP_U2OS_Human1.00653027
122AR_21572438_ChIP-Seq_LNCaP_Human1.00085542
123CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99651751
124SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99454354
125PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99096010
126NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98714502
127STAT3_18555785_Chip-Seq_ESCs_Mouse0.98541167
128SMAD_19615063_ChIP-ChIP_OVARY_Human0.98284422
129RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.98131450
130EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97464318
131TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97174498
132EP300_21415370_ChIP-Seq_HL-1_Mouse0.96235979

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004270_analgesia4.72408948
2MP0002822_catalepsy4.65506867
3MP0006276_abnormal_autonomic_nervous4.06095239
4MP0002735_abnormal_chemical_nociception3.97609109
5MP0005410_abnormal_fertilization3.84491181
6MP0002734_abnormal_mechanical_nocicepti3.17890901
7MP0004859_abnormal_synaptic_plasticity3.04251814
8MP0003880_abnormal_central_pattern2.89293512
9MP0004858_abnormal_nervous_system2.88681498
10MP0005084_abnormal_gallbladder_morpholo2.74277314
11MP0002653_abnormal_ependyma_morphology2.67335261
12MP0003635_abnormal_synaptic_transmissio2.60139614
13MP0008877_abnormal_DNA_methylation2.48710944
14MP0001529_abnormal_vocalization2.46586878
15MP0001968_abnormal_touch/_nociception2.45933592
16MP0009046_muscle_twitch2.42200653
17MP0001986_abnormal_taste_sensitivity2.41263437
18MP0009745_abnormal_behavioral_response2.38620094
19MP0002733_abnormal_thermal_nociception2.36695763
20MP0001970_abnormal_pain_threshold2.29569239
21MP0001188_hyperpigmentation2.27948067
22MP0002736_abnormal_nociception_after2.26221145
23MP0001905_abnormal_dopamine_level2.24701490
24MP0000372_irregular_coat_pigmentation2.20984834
25MP0003011_delayed_dark_adaptation2.19654376
26MP0002184_abnormal_innervation2.13176690
27MP0002928_abnormal_bile_duct2.10234056
28MP0010386_abnormal_urinary_bladder2.09151211
29MP0002063_abnormal_learning/memory/cond2.03763959
30MP0002272_abnormal_nervous_system2.03531129
31MP0003283_abnormal_digestive_organ2.03288579
32MP0002064_seizures2.00845385
33MP0001440_abnormal_grooming_behavior2.00023735
34MP0003195_calcinosis1.99142684
35MP0003698_abnormal_male_reproductive1.97627728
36MP0002751_abnormal_autonomic_nervous1.92695907
37MP0002572_abnormal_emotion/affect_behav1.90991025
38MP0005409_darkened_coat_color1.89388583
39MP0009384_cardiac_valve_regurgitation1.88468617
40MP0002067_abnormal_sensory_capabilities1.78432203
41MP0002277_abnormal_respiratory_mucosa1.69879587
42MP0002234_abnormal_pharynx_morphology1.69859174
43MP0002638_abnormal_pupillary_reflex1.69854583
44MP0001485_abnormal_pinna_reflex1.65902349
45MP0000778_abnormal_nervous_system1.63689722
46MP0000955_abnormal_spinal_cord1.63521605
47MP0000026_abnormal_inner_ear1.58307885
48MP0005386_behavior/neurological_phenoty1.57876308
49MP0004924_abnormal_behavior1.57876308
50MP0001929_abnormal_gametogenesis1.57671130
51MP0001486_abnormal_startle_reflex1.53109979
52MP0005451_abnormal_body_composition1.52786454
53MP0000569_abnormal_digit_pigmentation1.47521434
54MP0004811_abnormal_neuron_physiology1.44130399
55MP0002160_abnormal_reproductive_system1.42853648
56MP0000538_abnormal_urinary_bladder1.42754831
57MP0004215_abnormal_myocardial_fiber1.40188405
58MP0002557_abnormal_social/conspecific_i1.37823573
59MP0005174_abnormal_tail_pigmentation1.37071621
60MP0004142_abnormal_muscle_tone1.36692818
61MP0008569_lethality_at_weaning1.34604289
62MP0002210_abnormal_sex_determination1.31495576
63MP0003938_abnormal_ear_development1.30684589
64MP0002882_abnormal_neuron_morphology1.30321374
65MP0003879_abnormal_hair_cell1.30045782
66MP0003136_yellow_coat_color1.29898881
67MP0001501_abnormal_sleep_pattern1.28369651
68MP0004043_abnormal_pH_regulation1.26756918
69MP0008872_abnormal_physiological_respon1.20242245
70MP0003868_abnormal_feces_composition1.19632018
71MP0005423_abnormal_somatic_nervous1.18811034
72MP0001324_abnormal_eye_pigmentation1.17464950
73MP0005085_abnormal_gallbladder_physiolo1.15710887
74MP0009250_abnormal_appendicular_skeleto1.13503731
75MP0005623_abnormal_meninges_morphology1.13359000
76MP0008995_early_reproductive_senescence1.13008029
77MP0001984_abnormal_olfaction1.12778091
78MP0002066_abnormal_motor_capabilities/c1.12472927
79MP0000751_myopathy1.08336987
80MP0003329_amyloid_beta_deposits1.05136398
81MP0002161_abnormal_fertility/fecundity1.04692796
82MP0002752_abnormal_somatic_nervous1.04661914
83MP0000383_abnormal_hair_follicle1.03650389
84MP0003633_abnormal_nervous_system1.03389765
85MP0001145_abnormal_male_reproductive1.02644817
86MP0002229_neurodegeneration1.02553371
87MP0000613_abnormal_salivary_gland0.99947583
88MP0005253_abnormal_eye_physiology0.96180908
89MP0003631_nervous_system_phenotype0.93949278
90MP0000653_abnormal_sex_gland0.93749101
91MP0001293_anophthalmia0.93126415
92MP0009379_abnormal_foot_pigmentation0.92955609
93MP0001764_abnormal_homeostasis0.91500119
94MP0006072_abnormal_retinal_apoptosis0.90708987
95MP0001348_abnormal_lacrimal_gland0.90222272
96MP0010329_abnormal_lipoprotein_level0.89205102
97MP0002152_abnormal_brain_morphology0.88773667
98MP0002876_abnormal_thyroid_physiology0.86916240
99MP0005083_abnormal_biliary_tract0.86221658
100MP0005535_abnormal_body_temperature0.85577040
101MP0002909_abnormal_adrenal_gland0.85103065
102MP0005389_reproductive_system_phenotype0.84534936
103MP0002138_abnormal_hepatobiliary_system0.83172459
104MP0003634_abnormal_glial_cell0.82679145
105MP0003646_muscle_fatigue0.82612184
106MP0003252_abnormal_bile_duct0.81485709
107MP0008874_decreased_physiological_sensi0.80774140
108MP0005551_abnormal_eye_electrophysiolog0.76771232
109MP0002090_abnormal_vision0.76734374
110MP0000015_abnormal_ear_pigmentation0.76293820
111MP0005332_abnormal_amino_acid0.75490880
112MP0005365_abnormal_bile_salt0.74955296
113MP0001963_abnormal_hearing_physiology0.73807072
114MP0003690_abnormal_glial_cell0.71406625
115MP0005646_abnormal_pituitary_gland0.71262291
116MP0005499_abnormal_olfactory_system0.71120444
117MP0005394_taste/olfaction_phenotype0.71120444
118MP0005195_abnormal_posterior_eye0.70603067
119MP0003950_abnormal_plasma_membrane0.70459323
120MP0005408_hypopigmentation0.68113591
121MP0002837_dystrophic_cardiac_calcinosis0.66972687
122MP0000631_abnormal_neuroendocrine_gland0.66405607
123MP0002069_abnormal_eating/drinking_beha0.65584578
124MP0000639_abnormal_adrenal_gland0.65271478
125MP0000427_abnormal_hair_cycle0.65223079
126MP0002102_abnormal_ear_morphology0.65009891
127MP0002282_abnormal_trachea_morphology0.64145024
128MP0000467_abnormal_esophagus_morphology0.62518049
129MP0008260_abnormal_autophagy0.61690945
130MP0002249_abnormal_larynx_morphology0.61553171
131MP0004085_abnormal_heartbeat0.61471874
132MP0008789_abnormal_olfactory_epithelium0.61177308
133MP0001944_abnormal_pancreas_morphology0.59366436
134MP0000230_abnormal_systemic_arterial0.58736212
135MP0001919_abnormal_reproductive_system0.57835807
136MP0005171_absent_coat_pigmentation0.57449147
137MP0001727_abnormal_embryo_implantation0.56598794
138MP0003936_abnormal_reproductive_system0.56575967
139MP0008875_abnormal_xenobiotic_pharmacok0.56491907
140MP0009780_abnormal_chondrocyte_physiolo0.55984316
141MP0003861_abnormal_nervous_system0.55628309
142MP0002139_abnormal_hepatobiliary_system0.54912182
143MP0003122_maternal_imprinting0.54719793
144MP0004484_altered_response_of0.54666024
145MP0002095_abnormal_skin_pigmentation0.54025299
146MP0003632_abnormal_nervous_system0.53880708
147MP0003119_abnormal_digestive_system0.52663119
148MP0004742_abnormal_vestibular_system0.52455794
149MP0003137_abnormal_impulse_conducting0.50552526
150MP0003183_abnormal_peptide_metabolism0.49838557
151MP0003953_abnormal_hormone_level0.48317173
152MP0001286_abnormal_eye_development0.47941154
153MP0002938_white_spotting0.47790458

Predicted human phenotypes

RankGene SetZ-score
1Oligodactyly (hands) (HP:0001180)7.78673320
2Hypoplastic pelvis (HP:0008839)7.64646190
3Hypothermia (HP:0002045)7.50554669
4Fibular aplasia (HP:0002990)7.42994840
5Aplasia/Hypoplasia of the pubic bone (HP:0009104)7.33197724
6Split foot (HP:0001839)6.45549458
7Synostosis involving the elbow (HP:0003938)6.32612323
8Humeroradial synostosis (HP:0003041)6.32612323
9Myokymia (HP:0002411)6.04428790
10Adactyly (HP:0009776)5.58599556
11Aplasia/hypoplasia of the uterus (HP:0008684)5.42975308
12Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.36123922
13Oligodactyly (HP:0012165)5.15418495
14Aplasia/Hypoplasia involving the carpal bones (HP:0006502)5.05816054
15Absent/shortened dynein arms (HP:0200106)4.87939891
16Dynein arm defect of respiratory motile cilia (HP:0012255)4.87939891
17Radial bowing (HP:0002986)4.83072802
18Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)4.52874779
19Abnormality of the lower motor neuron (HP:0002366)4.48981045
20Abnormality of the pubic bones (HP:0003172)4.32086222
21Broad ribs (HP:0000885)4.30431275
22Ulnar claw (HP:0001178)4.27679361
23Hypoplastic nipples (HP:0002557)4.24068371
24Abnormal finger flexion creases (HP:0006143)4.08434745
25Barrel-shaped chest (HP:0001552)4.08120933
26Orthostatic hypotension (HP:0001278)4.01340861
27Hypoplastic iliac wings (HP:0002866)3.99087772
28Symphalangism affecting the phalanges of the hand (HP:0009773)3.89441086
29Abnormal respiratory motile cilium physiology (HP:0012261)3.82201255
30Progressive cerebellar ataxia (HP:0002073)3.62508013
31Febrile seizures (HP:0002373)3.61051994
32Aplasia/Hypoplasia of the 5th finger (HP:0006262)3.60843100
33Termporal pattern (HP:0011008)3.59477088
34Insidious onset (HP:0003587)3.59477088
35Skull defect (HP:0001362)3.55961219
36Congenital stationary night blindness (HP:0007642)3.47230862
37Abnormal autonomic nervous system physiology (HP:0012332)3.45676675
38Action tremor (HP:0002345)3.37701015
39Limb dystonia (HP:0002451)3.36076047
40Amyotrophic lateral sclerosis (HP:0007354)3.35483423
41Focal motor seizures (HP:0011153)3.34366902
42Aplasia/Hypoplasia of the fibula (HP:0006492)3.29558097
43Focal seizures (HP:0007359)3.16874356
44Bowed forearm bones (HP:0003956)3.11541940
45Bowing of the arm (HP:0006488)3.11541940
46Hypoventilation (HP:0002791)3.08583265
47Type II lissencephaly (HP:0007260)3.02573261
48Rhinitis (HP:0012384)3.02474141
49Abnormal respiratory epithelium morphology (HP:0012253)2.98737731
50Abnormal respiratory motile cilium morphology (HP:0005938)2.98737731
51Abnormal ciliary motility (HP:0012262)2.97493872
52Generalized tonic-clonic seizures (HP:0002069)2.95734947
53Infertility (HP:0000789)2.90226797
54Abnormality of the corticospinal tract (HP:0002492)2.83815418
55Hemivertebrae (HP:0002937)2.81108683
56Amblyopia (HP:0000646)2.79294718
57Autoamputation (HP:0001218)2.77018741
58Atonic seizures (HP:0010819)2.74495000
59Meningocele (HP:0002435)2.72611802
60Progressive inability to walk (HP:0002505)2.69952488
61Abnormality of pain sensation (HP:0010832)2.69393147
62Impaired pain sensation (HP:0007328)2.69393147
63Decreased motor nerve conduction velocity (HP:0003431)2.68005188
64Ankle clonus (HP:0011448)2.66525599
65Abdominal situs inversus (HP:0003363)2.63921275
66Abnormality of abdominal situs (HP:0011620)2.63921275
67Supranuclear gaze palsy (HP:0000605)2.63577676
68Agitation (HP:0000713)2.63267038
69Aplasia/Hypoplasia of the ulna (HP:0006495)2.60003114
70Abnormality of the wing of the ilium (HP:0011867)2.56081415
71Tarsal synostosis (HP:0008368)2.55732951
72Decreased number of peripheral myelinated nerve fibers (HP:0003380)2.55258256
73Mesangial abnormality (HP:0001966)2.53874898
74Absent forearm bone (HP:0003953)2.53674252
75Aplasia involving forearm bones (HP:0009822)2.53674252
76Aplasia/hypoplasia of the femur (HP:0005613)2.48819241
77Patellar aplasia (HP:0006443)2.48818974
78Abnormality of midbrain morphology (HP:0002418)2.48653213
79Molar tooth sign on MRI (HP:0002419)2.48653213
80Steppage gait (HP:0003376)2.47587126
81Akinesia (HP:0002304)2.47371958
82Pancreatic fibrosis (HP:0100732)2.47296614
83Hyperventilation (HP:0002883)2.46834799
84Gaze-evoked nystagmus (HP:0000640)2.42036911
85Chronic bronchitis (HP:0004469)2.41624114
86Pancreatic cysts (HP:0001737)2.41506047
87Femoral bowing (HP:0002980)2.40825917
88Decreased circulating renin level (HP:0003351)2.39785722
89Distal sensory impairment (HP:0002936)2.39116044
90Synostosis involving bones of the feet (HP:0009140)2.38843076
91Synostosis involving bones of the lower limbs (HP:0009138)2.38843076
92Cystic liver disease (HP:0006706)2.38819157
93Pheochromocytoma (HP:0002666)2.37408131
94Abnormality of the vocal cords (HP:0008777)2.36482472
95Short tibia (HP:0005736)2.35474755
96Aplasia/Hypoplasia of the patella (HP:0006498)2.33651753
97Urinary urgency (HP:0000012)2.33638558
98Dysdiadochokinesis (HP:0002075)2.32230493
99Sensory axonal neuropathy (HP:0003390)2.31865938
100Gait imbalance (HP:0002141)2.28858037
101Hypercortisolism (HP:0001578)2.28140889
102Spastic gait (HP:0002064)2.27195282
103True hermaphroditism (HP:0010459)2.25687722
104Genital tract atresia (HP:0001827)2.25672634
105Hypoplastic ilia (HP:0000946)2.22185211
106Urinary bladder sphincter dysfunction (HP:0002839)2.22064539
107Medial flaring of the eyebrow (HP:0010747)2.20163889
108Upper motor neuron abnormality (HP:0002127)2.19887366
109Lower limb amyotrophy (HP:0007210)2.18631158
110Aplasia/Hypoplasia of the tibia (HP:0005772)2.17714876
111Aplasia/Hypoplasia involving the pelvis (HP:0009103)2.16719713
112Ulnar deviation of finger (HP:0009465)2.16035987
113Fetal akinesia sequence (HP:0001989)2.15521250
114Neonatal onset (HP:0003623)2.14327875
115Lissencephaly (HP:0001339)2.14210389
116Aplasia/Hypoplasia of the nipples (HP:0006709)2.13767506
117Neuroendocrine neoplasm (HP:0100634)2.13368785
118Hyporeflexia of lower limbs (HP:0002600)2.13248167
119Hyperglycinemia (HP:0002154)2.11515899
120Myotonia (HP:0002486)2.10186185
121Bradycardia (HP:0001662)2.09850812
122Abnormality of the fibula (HP:0002991)2.09632619
123Hypoplasia of the radius (HP:0002984)2.09200325
124Epileptic encephalopathy (HP:0200134)2.08965510
125Visual hallucinations (HP:0002367)2.07874067
126Dysautonomia (HP:0002459)2.07522488
127Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.07319739
128Degeneration of the lateral corticospinal tracts (HP:0002314)2.07319739
129Cerebellar dysplasia (HP:0007033)2.06432355
130Hypoplasia of the brainstem (HP:0002365)2.05033802
131Aplasia/Hypoplasia of the brainstem (HP:0007362)2.05033802
132Aplasia/Hypoplasia of the macula (HP:0008059)2.04341108
133Decreased skull ossification (HP:0004331)2.03534227
134Foot dorsiflexor weakness (HP:0009027)2.01287234
135Sclerocornea (HP:0000647)2.00907152
136Vaginal atresia (HP:0000148)2.00387448
137Aplasia/Hypoplasia affecting the retina (HP:0008061)2.00026710
138Neonatal hypoglycemia (HP:0001998)1.98415598
139Scrotal hypoplasia (HP:0000046)1.98303833
140Hyperthyroidism (HP:0000836)1.97986214
141Lower limb muscle weakness (HP:0007340)1.97501232
142Nephronophthisis (HP:0000090)1.96487284
143Anxiety (HP:0000739)1.94255395
144Albinism (HP:0001022)1.93871924
145Impaired vibration sensation in the lower limbs (HP:0002166)1.92509689
146Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.92016658
147Postaxial hand polydactyly (HP:0001162)1.91631103
148Short foot (HP:0001773)1.90553559
149Segmental peripheral demyelination/remyelination (HP:0003481)1.90342597
150Hypotension (HP:0002615)1.90313382
151Abolished electroretinogram (ERG) (HP:0000550)1.90098173
152Delayed gross motor development (HP:0002194)1.89924325
153Morphological abnormality of the pyramidal tract (HP:0002062)1.88944715
154Hammertoe (HP:0001765)1.88668185
155Thyroid carcinoma (HP:0002890)1.88562562
156External ophthalmoplegia (HP:0000544)1.88497888
157Aplasia/Hypoplasia of the clavicles (HP:0006710)1.85820479
158Retinal atrophy (HP:0001105)1.82705095
159Onion bulb formation (HP:0003383)1.81911942
160Chronic hepatic failure (HP:0100626)1.81711606
161Shoulder girdle muscle weakness (HP:0003547)1.81683355
162Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.80684431
163Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.80526913
164Aplasia/Hypoplasia of the lens (HP:0008063)1.79658926
165Absence seizures (HP:0002121)1.79623113
166Congenital primary aphakia (HP:0007707)1.79335693
167Inability to walk (HP:0002540)1.78104066
168Paraplegia (HP:0010550)1.77008918
169Tubular atrophy (HP:0000092)1.76898802
170Arthropathy (HP:0003040)1.76699774
171Hyperglycinuria (HP:0003108)1.76251414
172Retinal dysplasia (HP:0007973)1.75178200
173Forearm undergrowth (HP:0009821)1.74988093
174Exotropia (HP:0000577)1.74445363
175Abnormality of the foot musculature (HP:0001436)1.74275838
176Blue irides (HP:0000635)1.72195343
177Clumsiness (HP:0002312)1.72121651
178Abnormality of the humerus (HP:0003063)1.71383347
179Abnormality of the renal medulla (HP:0100957)1.70986918
180Anophthalmia (HP:0000528)1.70782498
181Decreased electroretinogram (ERG) amplitude (HP:0000654)1.68705140
182Abnormal drinking behavior (HP:0030082)1.68501883
183Polydipsia (HP:0001959)1.68501883
184Abnormality of the upper arm (HP:0001454)1.67343996
185Abnormality of skull ossification (HP:0002703)1.63083604
186Large for gestational age (HP:0001520)1.59449474

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK8.12646968
2NTRK33.83386684
3NTRK13.75389819
4FRK3.52091891
5STK38L3.36007674
6MARK13.27431537
7PDK33.27348705
8PDK43.27348705
9MAPK133.05351058
10MAP3K42.94492854
11LIMK12.91649929
12GRK72.75221245
13MAP2K72.74142459
14MINK12.73389683
15LATS12.39720318
16PNCK2.39243575
17CASK2.30475406
18NTRK22.23715220
19MAPK152.21376763
20INSRR2.19310449
21BMPR22.05118981
22LMTK22.02287229
23ACVR1B2.00187993
24TAOK31.94448627
25EPHA31.87383171
26PDK21.82962914
27STK391.80062160
28MATK1.79170756
29GRK51.77253742
30TGFBR11.74024870
31MAP2K41.71922333
32WNK31.68543551
33PRKD31.66784476
34WNK11.64745257
35WNK41.58646645
36PHKG21.57261166
37PHKG11.57261166
38MAP3K121.56300508
39ADRBK21.54554834
40STK101.46143809
41MARK31.43927578
42GRK11.37867442
43MAP4K21.36481392
44TESK11.34913417
45UHMK11.32373286
46ARAF1.28734719
47MUSK1.24163842
48LATS21.23207781
49DYRK21.22388140
50PTK2B1.17723552
51MAP3K91.14689694
52SGK4941.14385893
53SGK2231.14385893
54CDC42BPA1.12967888
55EPHB11.08835905
56TXK1.07306392
57PKN11.06976961
58BCR1.04669740
59CAMKK11.03918235
60YES11.03497476
61STK111.01127854
62CSNK1G21.00931529
63MAP2K10.99891575
64PRKCG0.99598515
65PAK60.99134757
66SIK30.96511787
67CSNK1G30.94961432
68RPS6KA20.90984601
69STK30.89851994
70SGK20.89536856
71CDK50.87876052
72CHUK0.85409266
73MAPKAPK30.84529243
74KSR20.82574577
75MAPKAPK50.82296312
76RET0.81238197
77PLK20.80760345
78ADRBK10.80235133
79IKBKB0.79777853
80HIPK20.75489269
81PRKAA20.74687844
82IRAK20.74676976
83NUAK10.74362147
84CSF1R0.73789120
85DAPK20.73028738
86TYRO30.72099923
87CAMK2A0.71009432
88PIM10.69968172
89PRKCE0.66023780
90FER0.65561813
91SIK20.64665480
92AKT30.64557063
93ERBB20.62340924
94ICK0.60264468
95CAMKK20.59505845
96ZAK0.58505846
97MAP3K20.57848419
98CSNK1G10.56247003
99NLK0.53906471
100CDK80.50663438
101MAPK40.50573389
102TLK10.50242969
103DDR20.50107992
104PRKCZ0.49588112
105CAMK10.49014406
106ROCK20.48738778
107MAPK120.48336067
108CDK140.47778553
109PRKACB0.47071617
110PINK10.46833833
111STK380.46554595
112PIK3CG0.46106257
113RIPK40.44527970
114CAMK2G0.43944786
115CSNK1A1L0.43653659
116MAP3K10.43460628
117CDK90.43420365
118PRKCH0.42818215
119FES0.42735493
120ROCK10.42243621
121SGK30.41914711
122MAP3K70.41561272
123MAP2K60.41544260
124ERBB40.41464539
125IRAK10.41437461
126SGK10.40809038
127OBSCN0.40239987
128TIE10.39458336
129CAMK2B0.39235584
130PRKCQ0.39020835
131PRKACA0.38123873
132BMPR1B0.37707069
133RPS6KB10.35459409
134IKBKE0.34926821
135PRPF4B0.34721158
136KIT0.34064905
137DYRK1A0.33914262
138CSNK1A10.33769864
139STK240.33332661
140CSNK1E0.32231944
141PRKCB0.32125672
142PRKG10.31724635
143PLK40.31594123
144PAK30.31147146
145ITK0.30505335
146JAK10.30380339
147DYRK1B0.29121231
148IGF1R0.29116536
149GSK3A0.28927025
150TRIM280.28794803
151OXSR10.28522627
152NEK90.28510836
153ERBB30.27850958
154CDK180.26117767
155MAPK80.25898693
156KSR10.25889301
157CAMK2D0.25222549

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004304.26778455
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.94143606
3Synaptic vesicle cycle_Homo sapiens_hsa047213.47371601
4Amphetamine addiction_Homo sapiens_hsa050312.58071824
5Collecting duct acid secretion_Homo sapiens_hsa049662.54468994
6Dopaminergic synapse_Homo sapiens_hsa047282.29550904
7Cocaine addiction_Homo sapiens_hsa050302.29336446
8Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.28947329
9Oxidative phosphorylation_Homo sapiens_hsa001902.25460934
10Basal cell carcinoma_Homo sapiens_hsa052172.20304339
11Nicotine addiction_Homo sapiens_hsa050332.11006248
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.10207113
13Dorso-ventral axis formation_Homo sapiens_hsa043202.08175369
14Cholinergic synapse_Homo sapiens_hsa047252.02414725
15Primary bile acid biosynthesis_Homo sapiens_hsa001202.01796276
16Parkinsons disease_Homo sapiens_hsa050121.92809722
17Glutamatergic synapse_Homo sapiens_hsa047241.90125369
18Olfactory transduction_Homo sapiens_hsa047401.87298182
19Serotonergic synapse_Homo sapiens_hsa047261.85679499
20Circadian entrainment_Homo sapiens_hsa047131.80359878
21Long-term potentiation_Homo sapiens_hsa047201.79359250
22Taste transduction_Homo sapiens_hsa047421.74320412
23Fatty acid elongation_Homo sapiens_hsa000621.71495228
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.71267335
25Protein export_Homo sapiens_hsa030601.66126394
26Alzheimers disease_Homo sapiens_hsa050101.65683975
27Renin secretion_Homo sapiens_hsa049241.62496943
28Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.62021523
29Huntingtons disease_Homo sapiens_hsa050161.61680271
30Insulin secretion_Homo sapiens_hsa049111.61481150
31Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.60807613
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.57690917
33Tryptophan metabolism_Homo sapiens_hsa003801.53540974
34Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.52943541
35Phenylalanine metabolism_Homo sapiens_hsa003601.52603896
36Nitrogen metabolism_Homo sapiens_hsa009101.52123895
37Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51128218
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.48944806
39Complement and coagulation cascades_Homo sapiens_hsa046101.45581040
40Axon guidance_Homo sapiens_hsa043601.43752203
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.42302834
42Salivary secretion_Homo sapiens_hsa049701.40653125
43Tyrosine metabolism_Homo sapiens_hsa003501.40638247
44Butanoate metabolism_Homo sapiens_hsa006501.37118732
45Vibrio cholerae infection_Homo sapiens_hsa051101.35947578
46Caffeine metabolism_Homo sapiens_hsa002321.35501289
47Pyruvate metabolism_Homo sapiens_hsa006201.32699922
48Retinol metabolism_Homo sapiens_hsa008301.32239738
49Vitamin digestion and absorption_Homo sapiens_hsa049771.30860738
50Steroid hormone biosynthesis_Homo sapiens_hsa001401.30655147
51Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.27402117
52Morphine addiction_Homo sapiens_hsa050321.25929951
53Cardiac muscle contraction_Homo sapiens_hsa042601.25546415
54Long-term depression_Homo sapiens_hsa047301.24657019
55Phototransduction_Homo sapiens_hsa047441.24121166
56Gastric acid secretion_Homo sapiens_hsa049711.23909351
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.23787899
58GnRH signaling pathway_Homo sapiens_hsa049121.22098615
59Pancreatic secretion_Homo sapiens_hsa049721.21867682
60GABAergic synapse_Homo sapiens_hsa047271.19954337
61Calcium signaling pathway_Homo sapiens_hsa040201.19665842
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.18049246
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15741141
64Glucagon signaling pathway_Homo sapiens_hsa049221.15175194
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14425519
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.13086205
67Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.09940323
68Oxytocin signaling pathway_Homo sapiens_hsa049211.04827857
69Gap junction_Homo sapiens_hsa045401.03408692
70Arachidonic acid metabolism_Homo sapiens_hsa005901.02575495
71ABC transporters_Homo sapiens_hsa020101.02376891
72Chemical carcinogenesis_Homo sapiens_hsa052041.02245399
73Staphylococcus aureus infection_Homo sapiens_hsa051500.99421623
74Histidine metabolism_Homo sapiens_hsa003400.98892192
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.98400872
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98026691
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.97527704
78Cysteine and methionine metabolism_Homo sapiens_hsa002700.92409607
79Peroxisome_Homo sapiens_hsa041460.91280700
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91121552
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.88084397
82cAMP signaling pathway_Homo sapiens_hsa040240.87965703
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.87695160
84Intestinal immune network for IgA production_Homo sapiens_hsa046720.86174169
85ErbB signaling pathway_Homo sapiens_hsa040120.85973114
86Oocyte meiosis_Homo sapiens_hsa041140.85135872
87Estrogen signaling pathway_Homo sapiens_hsa049150.84713776
88Linoleic acid metabolism_Homo sapiens_hsa005910.84030965
89Fat digestion and absorption_Homo sapiens_hsa049750.83508904
90Phagosome_Homo sapiens_hsa041450.82463798
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81032906
92Melanogenesis_Homo sapiens_hsa049160.79209948
93Hippo signaling pathway_Homo sapiens_hsa043900.78223917
94Fatty acid biosynthesis_Homo sapiens_hsa000610.76365032
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74386789
96Type II diabetes mellitus_Homo sapiens_hsa049300.73565465
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73444010
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.73062724
99Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70967464
100Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.70092234
101Ether lipid metabolism_Homo sapiens_hsa005650.69051811
102Graft-versus-host disease_Homo sapiens_hsa053320.67631529
103Hedgehog signaling pathway_Homo sapiens_hsa043400.67594737
104cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63147432
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61267297
106Pentose and glucuronate interconversions_Homo sapiens_hsa000400.61036325
107Glycerolipid metabolism_Homo sapiens_hsa005610.59839031
108Alcoholism_Homo sapiens_hsa050340.58778443
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58170800
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.57920402
111Asthma_Homo sapiens_hsa053100.57678341
112Rheumatoid arthritis_Homo sapiens_hsa053230.56563441
113Fanconi anemia pathway_Homo sapiens_hsa034600.56474599
114Ovarian steroidogenesis_Homo sapiens_hsa049130.55781675
115Circadian rhythm_Homo sapiens_hsa047100.55066403
116VEGF signaling pathway_Homo sapiens_hsa043700.54881356
117African trypanosomiasis_Homo sapiens_hsa051430.54844976
118Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53111977
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52520801
120Thyroid hormone synthesis_Homo sapiens_hsa049180.52408968
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51982318
122Allograft rejection_Homo sapiens_hsa053300.51122772
123Bile secretion_Homo sapiens_hsa049760.50870274
124Type I diabetes mellitus_Homo sapiens_hsa049400.49698639
125Autoimmune thyroid disease_Homo sapiens_hsa053200.49383716
126Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.49290754
127Wnt signaling pathway_Homo sapiens_hsa043100.48768184
128Phospholipase D signaling pathway_Homo sapiens_hsa040720.46917372
129Mineral absorption_Homo sapiens_hsa049780.45851492
130Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.44571136
131Ras signaling pathway_Homo sapiens_hsa040140.43017877
132Propanoate metabolism_Homo sapiens_hsa006400.42631577
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40846073
134Prion diseases_Homo sapiens_hsa050200.40837252
135MAPK signaling pathway_Homo sapiens_hsa040100.40338411
136Glioma_Homo sapiens_hsa052140.38703804
137Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.38350331
138Basal transcription factors_Homo sapiens_hsa030220.38207738
139Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37819961
140Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37791415
141Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.37687957
142PPAR signaling pathway_Homo sapiens_hsa033200.37619087
143Inositol phosphate metabolism_Homo sapiens_hsa005620.37456305
144Proteasome_Homo sapiens_hsa030500.36675798
145Steroid biosynthesis_Homo sapiens_hsa001000.34322831
146Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34122656
147Fatty acid metabolism_Homo sapiens_hsa012120.33868191
148Selenocompound metabolism_Homo sapiens_hsa004500.33498994
149Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32771482
150Metabolic pathways_Homo sapiens_hsa011000.32299400
151Regulation of autophagy_Homo sapiens_hsa041400.32205646
152Central carbon metabolism in cancer_Homo sapiens_hsa052300.32167491
153Glycerophospholipid metabolism_Homo sapiens_hsa005640.31265796
154Drug metabolism - other enzymes_Homo sapiens_hsa009830.30472129

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »