LAIR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of defense response of other organism involved in symbiotic interaction (GO:07.35149247
2positive regulation by organism of defense response of other organism involved in symbiotic interact7.35149247
3modulation by symbiont of host immune response (GO:0052553)7.35149247
4positive regulation by symbiont of host defense response (GO:0052509)7.35149247
5modulation by symbiont of host defense response (GO:0052031)7.35149247
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:007.35149247
7microglial cell activation (GO:0001774)7.08559751
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.67355955
9regulation of interferon-beta biosynthetic process (GO:0045357)6.37516337
10macrophage activation involved in immune response (GO:0002281)6.18437767
11G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)5.84739169
12regulation of B cell receptor signaling pathway (GO:0050855)5.09966538
13response to host immune response (GO:0052572)4.97446824
14response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.97446824
15regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.74934273
16positive regulation of interferon-alpha production (GO:0032727)4.73383485
17response to host (GO:0075136)4.73320703
18response to host defenses (GO:0052200)4.73320703
19response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.73320703
20macrophage activation (GO:0042116)4.66251951
21positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.61785618
22response to peptidoglycan (GO:0032494)4.56689828
23neutrophil activation involved in immune response (GO:0002283)4.53976804
24regulation of interferon-alpha production (GO:0032647)4.50669811
25negative regulation of granulocyte differentiation (GO:0030853)4.36591466
26myeloid cell activation involved in immune response (GO:0002275)4.35992024
27positive regulation of chemokine secretion (GO:0090197)4.34535772
28immunoglobulin mediated immune response (GO:0016064)4.18271424
29purinergic nucleotide receptor signaling pathway (GO:0035590)4.11588613
30positive regulation of antigen processing and presentation (GO:0002579)4.05772496
31regulation of gamma-delta T cell activation (GO:0046643)4.03588814
32respiratory burst (GO:0045730)3.99125947
33response to muramyl dipeptide (GO:0032495)3.92033715
34cellular extravasation (GO:0045123)3.89746703
35positive regulation of B cell differentiation (GO:0045579)3.89189894
36G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.78643106
37positive regulation of gamma-delta T cell activation (GO:0046645)3.74399348
38antigen processing and presentation of endogenous antigen (GO:0019883)3.71897227
39I-kappaB phosphorylation (GO:0007252)3.68077762
40neutrophil mediated immunity (GO:0002446)3.63729287
41positive regulation of cellular amide metabolic process (GO:0034250)3.59205640
42pinocytosis (GO:0006907)3.56866079
43regulation of gamma-delta T cell differentiation (GO:0045586)3.52637255
44regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.51513073
45detection of other organism (GO:0098543)3.47062031
46glycosphingolipid catabolic process (GO:0046479)3.46590243
47antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.45108757
48neutrophil activation (GO:0042119)3.40590935
49germinal center formation (GO:0002467)3.40190800
50regulation of antigen processing and presentation (GO:0002577)3.37663500
51positive regulation of interferon-beta production (GO:0032728)3.35224094
52regulation of mast cell degranulation (GO:0043304)3.32738853
53positive thymic T cell selection (GO:0045059)3.32539185
54regulation of interleukin-8 biosynthetic process (GO:0045414)3.32529089
55detection of bacterium (GO:0016045)3.32403461
56granulocyte activation (GO:0036230)3.32237512
57negative regulation of cell killing (GO:0031342)3.30414956
58negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.30414956
59response to protozoan (GO:0001562)3.28405041
60regulation of chemokine secretion (GO:0090196)3.27177035
61myeloid leukocyte activation (GO:0002274)3.24645495
62positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.23062087
63antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.22326589
64B cell receptor signaling pathway (GO:0050853)3.20543434
65negative regulation of erythrocyte differentiation (GO:0045647)3.19902412
66hyaluronan catabolic process (GO:0030214)3.19454585
67purinergic receptor signaling pathway (GO:0035587)3.18291449
68regulation of mast cell activation involved in immune response (GO:0033006)3.15291754
69negative regulation of interleukin-12 production (GO:0032695)3.15146689
70lipopolysaccharide-mediated signaling pathway (GO:0031663)3.14541578
71positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.14540086
72negative regulation of interleukin-1 beta production (GO:0032691)3.13512818
73regulation of mast cell activation (GO:0033003)3.12018453
74mast cell activation (GO:0045576)3.11579359
75leukocyte aggregation (GO:0070486)3.10629347
76superoxide anion generation (GO:0042554)3.09386470
77negative regulation of interleukin-6 production (GO:0032715)3.08660339
78regulation of dendritic cell antigen processing and presentation (GO:0002604)3.06848043
79positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.06217330
80negative regulation of T cell mediated immunity (GO:0002710)3.06011045
81glycolipid catabolic process (GO:0019377)3.05906944
82regulation of hypersensitivity (GO:0002883)3.04965971
83detection of external biotic stimulus (GO:0098581)3.04247745
84positive regulation of mast cell activation (GO:0033005)2.97493266
85regulation of B cell differentiation (GO:0045577)2.97027284
86negative regulation of interleukin-17 production (GO:0032700)2.95489556
87T-helper 1 type immune response (GO:0042088)2.94063374
88production of molecular mediator involved in inflammatory response (GO:0002532)2.93667114
89B cell homeostasis (GO:0001782)2.93573075
90B cell mediated immunity (GO:0019724)2.90276729
91negative regulation of cytokine production involved in immune response (GO:0002719)2.89821742
92positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.89610439
93tolerance induction (GO:0002507)2.88417758
94positive regulation of mast cell activation involved in immune response (GO:0033008)2.86823411
95positive regulation of mast cell degranulation (GO:0043306)2.86823411
96ceramide catabolic process (GO:0046514)2.86385797
97cellular response to interferon-beta (GO:0035458)2.86127535
98T cell migration (GO:0072678)2.85921943
99leukocyte degranulation (GO:0043299)2.85638785
100detection of molecule of bacterial origin (GO:0032490)2.85025070
101phagocytosis, engulfment (GO:0006911)2.84607083
102leukocyte mediated cytotoxicity (GO:0001909)2.83614907
103positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.82955230
104detection of biotic stimulus (GO:0009595)2.81462342
105regulation of tolerance induction (GO:0002643)2.79834890
106negative regulation of leukocyte mediated immunity (GO:0002704)2.79638052
107negative regulation of interleukin-1 production (GO:0032692)2.79340147
108myeloid dendritic cell activation (GO:0001773)2.78789586
109negative regulation of growth of symbiont in host (GO:0044130)2.78085155
110negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.78085155
111modulation of growth of symbiont involved in interaction with host (GO:0044144)2.78085155
112regulation of growth of symbiont in host (GO:0044126)2.78085155
113negative regulation of lymphocyte mediated immunity (GO:0002707)2.76493551
114interferon-gamma-mediated signaling pathway (GO:0060333)2.76057000
115negative thymic T cell selection (GO:0045060)2.75791640
116mature B cell differentiation involved in immune response (GO:0002313)2.75517870
117negative regulation of innate immune response (GO:0045824)2.75469442
118histamine secretion (GO:0001821)2.75036066
119cellular response to thyroid hormone stimulus (GO:0097067)2.74367502
120myeloid leukocyte mediated immunity (GO:0002444)2.73998212
121regulation of leukocyte degranulation (GO:0043300)2.73465560
122positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.72899525
123regulation of T cell tolerance induction (GO:0002664)2.72827862
124regulation of mononuclear cell migration (GO:0071675)2.72731961
125regulation of interleukin-12 production (GO:0032655)2.71743509
126positive regulation of interleukin-1 beta secretion (GO:0050718)2.71548019
127regulation of macrophage chemotaxis (GO:0010758)2.71274157
128positive regulation of leukocyte degranulation (GO:0043302)2.71199794
129negative regulation of B cell proliferation (GO:0030889)2.70078501
130cellular response to exogenous dsRNA (GO:0071360)2.69897352
131neutrophil chemotaxis (GO:0030593)2.69688761
132regulation of interleukin-6 biosynthetic process (GO:0045408)2.69675485
133oligosaccharide catabolic process (GO:0009313)2.69226101
134G-protein coupled receptor internalization (GO:0002031)2.69116565
135cyclooxygenase pathway (GO:0019371)2.68978617
136regulation of myeloid leukocyte mediated immunity (GO:0002886)2.67927132
137negative regulation of mast cell activation (GO:0033004)2.67561194
138reactive oxygen species biosynthetic process (GO:1903409)2.66185118
139regulation of regulated secretory pathway (GO:1903305)2.65918485
140macrophage chemotaxis (GO:0048246)2.65292140
141monocyte chemotaxis (GO:0002548)2.64952944
142defense response to protozoan (GO:0042832)2.64411398
143adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.64177621
144regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.63236035

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse6.47244905
2BP1_19119308_ChIP-ChIP_Hs578T_Human5.69848939
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.43926626
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.98215725
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.71473741
6NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.79845102
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.79295987
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.75871929
9Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.57963799
10SCL_19346495_ChIP-Seq_HPC-7_Human3.51804047
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.43149330
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.16777766
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.08617303
14MYB_21317192_ChIP-Seq_ERMYB_Mouse3.01193587
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.86855874
16* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.84253064
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.67569513
18* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.56103679
19* SPI1_23547873_ChIP-Seq_NB4_Human2.43870059
20SPI1_23127762_ChIP-Seq_K562_Human2.37685115
21BRD4_27068464_Chip-Seq_AML-cells_Mouse2.35486078
22VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.30104706
23PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.23113541
24RUNX_20019798_ChIP-Seq_JUKART_Human2.17108395
25PU_27001747_Chip-Seq_BMDM_Mouse2.04656053
26STAT4_19710469_ChIP-ChIP_TH1__Mouse1.99782939
27RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.97410396
28PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.97317282
29VDR_24763502_ChIP-Seq_THP-1_Human1.97198935
30FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.96807466
31RUNX1_22412390_ChIP-Seq_EML_Mouse1.89897809
32NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.88301363
33VDR_24787735_ChIP-Seq_THP-1_Human1.87421651
34LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.80763699
35MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.75453543
36GATA1_22025678_ChIP-Seq_K562_Human1.71833806
37* MYB_26560356_Chip-Seq_TH2_Human1.68813478
38CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.68354083
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.61504887
40LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.59811652
41* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.57260559
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.56209165
43MYC_22102868_ChIP-Seq_BL_Human1.53243857
44GATA2_21666600_ChIP-Seq_HMVEC_Human1.50712060
45SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.49812165
46VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.48971366
47MYB_26560356_Chip-Seq_TH1_Human1.47384922
48* VDR_21846776_ChIP-Seq_THP-1_Human1.45905057
49MAF_26560356_Chip-Seq_TH1_Human1.45555778
50E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.43610168
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.42111376
52MAF_26560356_Chip-Seq_TH2_Human1.37353381
53STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.36933378
54GATA2_22383799_ChIP-Seq_G1ME_Mouse1.33905892
55* BCL6_27268052_Chip-Seq_Bcells_Human1.32732037
56NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.32021722
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.29551452
58STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.28672233
59* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.27240938
60* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.26381898
61STAT1_20625510_ChIP-Seq_HELA_Human1.25650932
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.24008034
63GATA1_19941827_ChIP-Seq_MEL_Mouse1.22686637
64CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19810885
65CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19473271
66PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16643967
67ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16047402
68GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.16023463
69SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15973411
70TCF7_22412390_ChIP-Seq_EML_Mouse1.15864899
71* GATA3_26560356_Chip-Seq_TH2_Human1.15001721
72* GATA3_27048872_Chip-Seq_THYMUS_Human1.14554070
73* BCOR_27268052_Chip-Seq_Bcells_Human1.13872600
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11752587
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11633061
76SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10011710
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08736429
78THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07343256
79* KDM2B_26808549_Chip-Seq_DND41_Human1.03670263
80* ELF1_20517297_ChIP-Seq_JURKAT_Human1.00491440
81FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97617697
82GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97434916
83* UTX_26944678_Chip-Seq_JUKART_Human0.96811601
84PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96572919
85STAT6_21828071_ChIP-Seq_BEAS2B_Human0.96280072
86GATA1_22383799_ChIP-Seq_G1ME_Mouse0.96161980
87KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.95138270
88LXR_22292898_ChIP-Seq_THP-1_Human0.92888577
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91458915
90E2F7_22180533_ChIP-Seq_HELA_Human0.91249089
91PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90375665
92* KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.89852960
93* P300_27268052_Chip-Seq_Bcells_Human0.88931899
94TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.88413906
95GATA2_19941826_ChIP-Seq_K562_Human0.86745865
96FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84446068
97CTCF_26484167_Chip-Seq_Bcells_Mouse0.82747130
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.82320929
99RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.80745002
100EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.80284403
101RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78431120
102RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.75238037
103CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.75072438
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.72844387
105IKZF1_21737484_ChIP-ChIP_HCT116_Human0.72837423
106PCGF2_27294783_Chip-Seq_NPCs_Mouse0.72209039
107FOXM1_23109430_ChIP-Seq_U2OS_Human0.71729562
108SMRT_27268052_Chip-Seq_Bcells_Human0.69766260
109GATA1_19941826_ChIP-Seq_K562_Human0.68226567
110TFEB_21752829_ChIP-Seq_HELA_Human0.65463150
111PU1_27457419_Chip-Seq_LIVER_Mouse0.64930741
112SUZ12_27294783_Chip-Seq_NPCs_Mouse0.63490801
113GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.62788038
114SPI1_20517297_ChIP-Seq_HL60_Human0.62714022
115TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.60700600
116PCGF2_27294783_Chip-Seq_ESCs_Mouse0.59604162
117TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.59446767
118ETS1_22383799_ChIP-Seq_G1ME_Mouse0.58791199
119NFE2_27457419_Chip-Seq_LIVER_Mouse0.57852838
120RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.57783076
121CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.57713533
122CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.56463394
123CDX2_19796622_ChIP-Seq_MESCs_Mouse0.55952744
124EZH2_27294783_Chip-Seq_NPCs_Mouse0.55233707
125KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.54458986

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.49497655
2MP0001835_abnormal_antigen_presentation4.37645330
3MP0006082_CNS_inflammation3.74360775
4MP0003172_abnormal_lysosome_physiology3.61020209
5MP0002419_abnormal_innate_immunity3.22601066
6MP0003191_abnormal_cellular_cholesterol3.20462891
7MP0003436_decreased_susceptibility_to3.10529438
8MP0005464_abnormal_platelet_physiology3.08432023
9MP0005671_abnormal_response_to3.04234322
10MP0000569_abnormal_digit_pigmentation3.03126248
11MP0003303_peritoneal_inflammation2.97503914
12MP0002148_abnormal_hypersensitivity_rea2.69703654
13MP0005000_abnormal_immune_tolerance2.62701272
14MP0002452_abnormal_antigen_presenting2.59364081
15MP0009785_altered_susceptibility_to2.46622283
16MP0005025_abnormal_response_to2.46467523
17MP0001800_abnormal_humoral_immune2.43971271
18MP0002723_abnormal_immune_serum2.39767001
19MP0003724_increased_susceptibility_to2.23925357
20MP0001819_abnormal_immune_cell2.21907376
21MP0002420_abnormal_adaptive_immunity2.20414398
22MP0001790_abnormal_immune_system2.15315461
23MP0005387_immune_system_phenotype2.15315461
24MP0002396_abnormal_hematopoietic_system2.12476462
25MP0003183_abnormal_peptide_metabolism2.11773477
26MP0003690_abnormal_glial_cell2.06944039
27MP0005174_abnormal_tail_pigmentation1.99772381
28MP0001533_abnormal_skeleton_physiology1.89277975
29MP0000685_abnormal_immune_system1.86907407
30MP0003075_altered_response_to1.80279354
31MP0003300_gastrointestinal_ulcer1.72168301
32MP0001845_abnormal_inflammatory_respons1.68889931
33MP0001853_heart_inflammation1.68051142
34MP0000716_abnormal_immune_system1.65441766
35MP0004510_myositis1.62225364
36MP0000343_altered_response_to1.62117264
37MP0000015_abnormal_ear_pigmentation1.59758613
38MP0008469_abnormal_protein_level1.58776110
39MP0002398_abnormal_bone_marrow1.57747966
40MP0002405_respiratory_system_inflammati1.57518279
41MP0000689_abnormal_spleen_morphology1.54817204
42MP0009840_abnormal_foam_cell1.44196088
43MP0000465_gastrointestinal_hemorrhage1.43782783
44MP0009278_abnormal_bone_marrow1.42783429
45MP0008004_abnormal_stomach_pH1.41770242
46MP0005310_abnormal_salivary_gland1.38958822
47MP0002998_abnormal_bone_remodeling1.38385694
48MP0001851_eye_inflammation1.36363938
49MP0002429_abnormal_blood_cell1.34844130
50MP0005397_hematopoietic_system_phenotyp1.33882774
51MP0001545_abnormal_hematopoietic_system1.33882774
52MP0010155_abnormal_intestine_physiology1.33822798
53MP0002722_abnormal_immune_system1.33310817
54MP0003806_abnormal_nucleotide_metabolis1.30954804
55MP0002166_altered_tumor_susceptibility1.29718420
56MP0004947_skin_inflammation1.28222781
57MP0003828_pulmonary_edema1.27920797
58MP0009333_abnormal_splenocyte_physiolog1.25663412
59MP0005166_decreased_susceptibility_to1.25101701
60MP0004808_abnormal_hematopoietic_stem1.19344035
61MP0002277_abnormal_respiratory_mucosa1.15678862
62MP0002138_abnormal_hepatobiliary_system1.15399791
63MP0000371_diluted_coat_color1.13393481
64MP0010307_abnormal_tumor_latency1.12414615
65MP0001873_stomach_inflammation1.11808585
66MP0002006_tumorigenesis1.11328746
67MP0003448_altered_tumor_morphology1.09986812
68MP0003045_fibrosis1.09907147
69MP0009764_decreased_sensitivity_to1.00770493
70MP0002139_abnormal_hepatobiliary_system0.99467399
71MP0003195_calcinosis0.99220839
72MP0001663_abnormal_digestive_system0.98880218
73MP0000858_altered_metastatic_potential0.97843720
74MP0004883_abnormal_blood_vessel0.96639581
75MP0000249_abnormal_blood_vessel0.92288344
76MP0000490_abnormal_crypts_of0.92212609
77MP0005167_abnormal_blood-brain_barrier0.92172082
78MP0002933_joint_inflammation0.91790532
79MP0005390_skeleton_phenotype0.89163467
80MP0003763_abnormal_thymus_physiology0.88789912
81MP0009763_increased_sensitivity_to0.88205278
82MP0003566_abnormal_cell_adhesion0.86032204
83MP0002928_abnormal_bile_duct0.85735621
84MP0000604_amyloidosis0.81089614
85MP0000703_abnormal_thymus_morphology0.80514581
86MP0000767_abnormal_smooth_muscle0.77183079
87MP0005075_abnormal_melanosome_morpholog0.76537861
88MP0001986_abnormal_taste_sensitivity0.75768162
89MP0005164_abnormal_response_to0.75662866
90MP0006054_spinal_hemorrhage0.74891061
91MP0003656_abnormal_erythrocyte_physiolo0.74720066
92MP0003866_abnormal_defecation0.74259588
93MP0009765_abnormal_xenobiotic_induced0.73553859
94MP0002095_abnormal_skin_pigmentation0.73154606
95MP0001915_intracranial_hemorrhage0.73143237
96MP0004130_abnormal_muscle_cell0.71227236
97MP0008007_abnormal_cellular_replicative0.71106693
98MP0003795_abnormal_bone_structure0.70746263
99MP0004782_abnormal_surfactant_physiolog0.70727913
100MP0002090_abnormal_vision0.68628728
101MP0005535_abnormal_body_temperature0.65985068
102MP0005670_abnormal_white_adipose0.65417708
103MP0003646_muscle_fatigue0.63073905
104MP0002132_abnormal_respiratory_system0.62906130
105MP0005409_darkened_coat_color0.62102447
106MP0002075_abnormal_coat/hair_pigmentati0.61768096
107MP0009115_abnormal_fat_cell0.61561641
108MP0005257_abnormal_intraocular_pressure0.61461211
109MP0000920_abnormal_myelination0.61079595
110MP0003252_abnormal_bile_duct0.60904592
111MP0008873_increased_physiological_sensi0.59671314
112MP0005319_abnormal_enzyme/_coenzyme0.59075431
113MP0003279_aneurysm0.58265735
114MP0005365_abnormal_bile_salt0.57966991
115MP0005334_abnormal_fat_pad0.57364421
116MP0008260_abnormal_autophagy0.55805776
117MP0002693_abnormal_pancreas_physiology0.54290773
118MP0005165_increased_susceptibility_to0.52620385
119MP0003638_abnormal_response/metabolism_0.51830374
120MP0005381_digestive/alimentary_phenotyp0.51391700

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.79454352
2Systemic lupus erythematosus (HP:0002725)6.61622782
3Recurrent bacterial skin infections (HP:0005406)6.40505950
4Eczematoid dermatitis (HP:0000976)5.40775100
5Abnormality of glycolipid metabolism (HP:0010969)5.39458617
6Abnormality of liposaccharide metabolism (HP:0010968)5.39458617
7Abnormality of glycosphingolipid metabolism (HP:0004343)5.39458617
8Glomerulonephritis (HP:0000099)5.11655281
9Increased cerebral lipofuscin (HP:0011813)4.98967041
10Increased neuronal autofluorescent lipopigment (HP:0002074)4.79116628
11Vacuolated lymphocytes (HP:0001922)4.56020984
12Dysostosis multiplex (HP:0000943)4.28452177
13Recurrent gram-negative bacterial infections (HP:0005420)4.26711259
14Recurrent skin infections (HP:0001581)3.96087831
15Abnormality of macrophages (HP:0004311)3.94332644
16Myositis (HP:0100614)3.72093172
17Disinhibition (HP:0000734)3.70862740
18Panhypogammaglobulinemia (HP:0003139)3.48532161
19Abnormal delayed hypersensitivity skin test (HP:0002963)3.40554602
20Abnormality of polysaccharide metabolism (HP:0011012)3.36334652
21Abnormality of glycosaminoglycan metabolism (HP:0004371)3.36334652
22Abnormality of mucopolysaccharide metabolism (HP:0011020)3.36334652
23Complement deficiency (HP:0004431)3.34516505
24Recurrent fungal infections (HP:0002841)3.29599552
25Mucopolysacchariduria (HP:0008155)3.29474861
26Urinary glycosaminoglycan excretion (HP:0003541)3.29474861
27Obstructive lung disease (HP:0006536)3.22062736
28Chronic obstructive pulmonary disease (HP:0006510)3.22062736
29Gingivitis (HP:0000230)3.21379168
30Agnosia (HP:0010524)3.19618254
31Prostate neoplasm (HP:0100787)3.18273607
32Elevated erythrocyte sedimentation rate (HP:0003565)3.16242064
33Axonal loss (HP:0003447)3.15355534
34Retinal atrophy (HP:0001105)3.13533691
35Encephalitis (HP:0002383)3.13024751
36Orchitis (HP:0100796)3.06885573
37Arterial tortuosity (HP:0005116)3.06647449
38Hematochezia (HP:0002573)3.06500207
39Abnormality of B cell number (HP:0010975)3.06303218
40Mediastinal lymphadenopathy (HP:0100721)3.03656975
41Agammaglobulinemia (HP:0004432)2.97534968
42Colitis (HP:0002583)2.96253779
43Retrobulbar optic neuritis (HP:0100654)2.95009210
44Optic neuritis (HP:0100653)2.95009210
45Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.85987859
46Hemoptysis (HP:0002105)2.83997509
47Recurrent viral infections (HP:0004429)2.83579209
48Increased IgE level (HP:0003212)2.81680097
49Recurrent cutaneous fungal infections (HP:0011370)2.81283819
50Chronic mucocutaneous candidiasis (HP:0002728)2.81283819
51Basal ganglia calcification (HP:0002135)2.78075280
52Abnormality of complement system (HP:0005339)2.77455479
53B lymphocytopenia (HP:0010976)2.77422685
54Hepatosplenomegaly (HP:0001433)2.75541282
55Nephritis (HP:0000123)2.75473050
56J-shaped sella turcica (HP:0002680)2.75137688
57T lymphocytopenia (HP:0005403)2.70171120
58Mutism (HP:0002300)2.66860328
59Chronic diarrhea (HP:0002028)2.65257013
60Inflammation of the large intestine (HP:0002037)2.63812962
61Stomatitis (HP:0010280)2.63545812
62Periodontitis (HP:0000704)2.63129689
63Urethral obstruction (HP:0000796)2.62554223
64Abnormality of T cell number (HP:0011839)2.60734170
65Vascular tortuosity (HP:0004948)2.58965246
66Upper motor neuron abnormality (HP:0002127)2.57522473
67Amyloidosis (HP:0011034)2.56126821
68Granulocytopenia (HP:0001913)2.55719534
69Keratoconjunctivitis sicca (HP:0001097)2.54678991
70Pustule (HP:0200039)2.50229389
71Gastrointestinal infarctions (HP:0005244)2.50206048
72Cellulitis (HP:0100658)2.48444445
73Abnormality of T cells (HP:0002843)2.48323110
74Combined immunodeficiency (HP:0005387)2.48057447
75Severe combined immunodeficiency (HP:0004430)2.47636196
76Keratoconjunctivitis (HP:0001096)2.47172499
77Thick nail (HP:0001805)2.46181799
78Spondylolisthesis (HP:0003302)2.46131313
79Abnormal platelet function (HP:0011869)2.45896846
80Impaired platelet aggregation (HP:0003540)2.45896846
81Meningitis (HP:0001287)2.45571076
82Pathologic fracture (HP:0002756)2.44540477
83Cerebral aneurysm (HP:0004944)2.43994844
84Thoracic kyphosis (HP:0002942)2.40587068
85Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.39820802
86Vasculitis (HP:0002633)2.37563026
87Loss of speech (HP:0002371)2.37388933
88Autoimmune thrombocytopenia (HP:0001973)2.36917758
89Increased serum ferritin (HP:0003281)2.36907580
90Gastrointestinal inflammation (HP:0004386)2.35715998
91Osteomyelitis (HP:0002754)2.34846738
92Prolonged bleeding time (HP:0003010)2.31060286
93Epistaxis (HP:0000421)2.28041726
94Purpura (HP:0000979)2.27777889
95Abnormality of the prostate (HP:0008775)2.27029673
96Recurrent pneumonia (HP:0006532)2.26400890
97Autoimmune hemolytic anemia (HP:0001890)2.24786384
98Progressive neurologic deterioration (HP:0002344)2.23811241
99Abnormality of iron homeostasis (HP:0011031)2.23393027
100Chest pain (HP:0100749)2.23190241
101Abnormality of T cell physiology (HP:0011840)2.23144550
102Increased IgM level (HP:0003496)2.22145115
103Arterial thrombosis (HP:0004420)2.18227689
104Pulmonary embolism (HP:0002204)2.15304339
105Eosinophilia (HP:0001880)2.14521916
106Hypergammaglobulinemia (HP:0010702)2.13179166
107Leukocytosis (HP:0001974)2.13014210
108Pulmonary infiltrates (HP:0002113)2.12638955
109Polyneuropathy (HP:0001271)2.11983306
110Petechiae (HP:0000967)2.10748327
111Gingival bleeding (HP:0000225)2.10254560
112Spontaneous hematomas (HP:0007420)2.08941475
113Abnormality of the pleura (HP:0002103)2.07651185
114Abnormality of eosinophils (HP:0001879)2.05696305
115Progressive visual loss (HP:0000529)2.04673002
116Abnormality of transition element cation homeostasis (HP:0011030)2.03319880
117Thrombocytosis (HP:0001894)2.03209980
118Abnormality of the thoracic spine (HP:0100711)2.02504233
119Bone pain (HP:0002653)2.02386069
120Inappropriate behavior (HP:0000719)2.01245221
121IgM deficiency (HP:0002850)2.00642129
122Joint hemorrhage (HP:0005261)2.00304157
123Abnormality of the vasculature of the conjunctiva (HP:0008054)1.96324742
124Gangrene (HP:0100758)1.95051667
125Chronic otitis media (HP:0000389)1.92142901
126Interstitial pulmonary disease (HP:0006530)1.91867004
127Sepsis (HP:0100806)1.90952087
128Osteolytic defects of the phalanges of the hand (HP:0009771)1.89869284
129Osteolytic defects of the hand bones (HP:0009699)1.89869284
130Chromosomal breakage induced by crosslinking agents (HP:0003221)1.88603279
131Vertigo (HP:0002321)1.87754501
132Abnormality of the lumbar spine (HP:0100712)1.86672599
133Urticaria (HP:0001025)1.86254575
134Recurrent lower respiratory tract infections (HP:0002783)1.85752106
135Striae distensae (HP:0001065)1.85464038
136Aortic aneurysm (HP:0004942)1.82912824
137Deformed sella turcica (HP:0002681)1.82905615

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR26.11689448
2GRK73.40417234
3IRAK43.28739174
4RIPK43.11087756
5BLK3.03459501
6TYK22.93936923
7IRAK32.90661562
8CSF1R2.85809654
9KIT2.76597532
10MAP4K12.42252777
11MAP3K142.36301211
12TBK12.28952593
13TXK2.15408802
14MAP2K32.07344985
15CAMK1D1.95295088
16MAPK151.94817129
17JAK11.93169543
18ZAP701.82183172
19ACVR1B1.81266049
20IKBKB1.77270941
21IKBKE1.76677304
22TEC1.71837444
23MAP3K111.69800394
24NME21.64883386
25STK101.62043021
26HCK1.55512861
27FES1.54430003
28GRK61.54329482
29TAOK31.53545426
30ITK1.51943216
31BTK1.40275875
32JAK31.38687919
33CAMK1G1.37810489
34CLK11.35248734
35SYK1.34251704
36CSK1.31831270
37EIF2AK21.30700623
38MATK1.26122771
39* LYN1.25187802
40DAPK21.20987267
41ADRBK21.20916339
42TLK11.20554475
43LCK1.15749805
44NEK91.15220634
45CAMKK21.11610852
46RPS6KA41.05642128
47MAP3K131.04419881
48CDK31.04271968
49PRPF4B1.03208703
50TGFBR10.97712812
51MAP3K60.96779313
52JAK20.95169713
53MAPK70.94649787
54TESK20.92321480
55YES10.91393200
56TAOK10.89597148
57MAPK120.88658511
58BCKDK0.86313308
59CDC42BPA0.84684575
60PAK40.84026285
61MAP2K60.83670991
62ABL20.82980975
63CHUK0.82564322
64MOS0.81422885
65TRPM70.79673400
66PIK3CG0.74408330
67SIK20.73236171
68FRK0.71276619
69FGR0.69130473
70CDK60.68776491
71CDK80.68756181
72ERN10.67690621
73MAP3K10.67255781
74TAOK20.67170303
75TNIK0.65681018
76HIPK20.62485562
77BMPR1B0.62441550
78CAMK40.59476065
79KDR0.55185175
80MAPKAPK20.54372159
81MARK30.53075574
82CDK120.52651858
83PIM10.52170639
84PDK10.52090422
85PRKD20.51806889
86EGFR0.51401970
87IGF1R0.51198196
88MAP3K30.50833636
89PDPK10.50497761
90FGFR30.48853219
91VRK10.48169486
92PRKCD0.46227945
93EPHB10.45648909
94TSSK60.44123371
95MAP2K20.43330296
96CAMKK10.42989479
97CDK40.42947905
98STK40.41596900
99MAPKAPK50.41405927
100FLT30.40077211
101IRAK10.39926965
102ABL10.39166156
103SGK30.38457875
104MARK20.38341323
105PIM20.37220176
106EEF2K0.34094431
107ADRBK10.34022472
108RPS6KA60.33295679
109BMPR20.33004366
110ZAK0.32769088
111MAPK110.31674759
112MAPK40.30837806
113SGK20.29468564
114MAPK30.28658105
115PRKAA20.27791935
116EPHA30.26399090
117RPS6KC10.26147697
118RPS6KL10.26147697
119PRKCQ0.26041929
120PDK20.25864599
121RPS6KA20.25781568
122BRD40.25718958
123FYN0.25102475
124TNK20.24828802
125GRK50.23575210
126SIK30.22110547
127MAP3K50.21725057
128IRAK20.20939461
129CAMK10.20162145

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051504.00412297
2Glycosaminoglycan degradation_Homo sapiens_hsa005313.94036239
3Other glycan degradation_Homo sapiens_hsa005113.50744832
4Leishmaniasis_Homo sapiens_hsa051402.98871728
5Lysosome_Homo sapiens_hsa041422.89942616
6Osteoclast differentiation_Homo sapiens_hsa043802.82904812
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.45683013
8Type I diabetes mellitus_Homo sapiens_hsa049402.42248444
9Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.26947046
10Pertussis_Homo sapiens_hsa051332.23641966
11B cell receptor signaling pathway_Homo sapiens_hsa046622.21144048
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.03511047
13Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.01761119
14Tuberculosis_Homo sapiens_hsa051522.01061918
15Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.85567701
16Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.82239158
17Measles_Homo sapiens_hsa051621.81122276
18Antigen processing and presentation_Homo sapiens_hsa046121.77366091
19Legionellosis_Homo sapiens_hsa051341.69982671
20Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.68985633
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.68546428
22Phagosome_Homo sapiens_hsa041451.55328767
23Influenza A_Homo sapiens_hsa051641.55282165
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.54300344
25Hematopoietic cell lineage_Homo sapiens_hsa046401.53706315
26Toxoplasmosis_Homo sapiens_hsa051451.51067006
27Malaria_Homo sapiens_hsa051441.49283757
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.46762592
29Rheumatoid arthritis_Homo sapiens_hsa053231.42609954
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42483060
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.34264628
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.31637631
33Chemokine signaling pathway_Homo sapiens_hsa040621.27749094
34TNF signaling pathway_Homo sapiens_hsa046681.25901410
35Apoptosis_Homo sapiens_hsa042101.20247459
36Herpes simplex infection_Homo sapiens_hsa051681.19998732
37Salmonella infection_Homo sapiens_hsa051321.14152410
38Graft-versus-host disease_Homo sapiens_hsa053321.10333478
39Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.10217021
40Jak-STAT signaling pathway_Homo sapiens_hsa046301.07488460
41Complement and coagulation cascades_Homo sapiens_hsa046101.04259257
42Pancreatic cancer_Homo sapiens_hsa052121.04093848
43Platelet activation_Homo sapiens_hsa046111.03760262
44Hepatitis B_Homo sapiens_hsa051611.03399966
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.00432790
46Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.98062101
47Primary immunodeficiency_Homo sapiens_hsa053400.96756760
48Chronic myeloid leukemia_Homo sapiens_hsa052200.95962925
49Shigellosis_Homo sapiens_hsa051310.93417885
50Allograft rejection_Homo sapiens_hsa053300.92341415
51Asthma_Homo sapiens_hsa053100.89314813
52AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.84285104
53Hepatitis C_Homo sapiens_hsa051600.83800629
54T cell receptor signaling pathway_Homo sapiens_hsa046600.82514165
55African trypanosomiasis_Homo sapiens_hsa051430.81283378
56Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.78998330
57Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.78592548
58ABC transporters_Homo sapiens_hsa020100.78336647
59Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.78169868
60Systemic lupus erythematosus_Homo sapiens_hsa053220.75511476
61Prion diseases_Homo sapiens_hsa050200.75472931
62Collecting duct acid secretion_Homo sapiens_hsa049660.75172825
63Transcriptional misregulation in cancer_Homo sapiens_hsa052020.73054034
64Acute myeloid leukemia_Homo sapiens_hsa052210.71441206
65Sphingolipid metabolism_Homo sapiens_hsa006000.70599722
66Caffeine metabolism_Homo sapiens_hsa002320.68150364
67Ether lipid metabolism_Homo sapiens_hsa005650.67912091
68alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66971207
69Sphingolipid signaling pathway_Homo sapiens_hsa040710.62541221
70Neurotrophin signaling pathway_Homo sapiens_hsa047220.61675147
71Adipocytokine signaling pathway_Homo sapiens_hsa049200.60279886
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.60138844
73Endocytosis_Homo sapiens_hsa041440.59947366
74Inositol phosphate metabolism_Homo sapiens_hsa005620.57133342
75Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50934640
76Amoebiasis_Homo sapiens_hsa051460.50424900
77Arachidonic acid metabolism_Homo sapiens_hsa005900.49958138
78Epstein-Barr virus infection_Homo sapiens_hsa051690.49136296
79Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.48383176
80Notch signaling pathway_Homo sapiens_hsa043300.45859597
81Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43055342
82Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42855668
83Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42086609
84Linoleic acid metabolism_Homo sapiens_hsa005910.41395557
85Colorectal cancer_Homo sapiens_hsa052100.40920938
86Viral myocarditis_Homo sapiens_hsa054160.40508160
87Prolactin signaling pathway_Homo sapiens_hsa049170.39672361
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38513759
89VEGF signaling pathway_Homo sapiens_hsa043700.35940367
90Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35546918
91Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.34647415
92Small cell lung cancer_Homo sapiens_hsa052220.33456427
93Dorso-ventral axis formation_Homo sapiens_hsa043200.33294591
94Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.31040868
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30887464
96Viral carcinogenesis_Homo sapiens_hsa052030.30389280
97Autoimmune thyroid disease_Homo sapiens_hsa053200.30147160
98Regulation of autophagy_Homo sapiens_hsa041400.30146278
99Renin-angiotensin system_Homo sapiens_hsa046140.30002532
100Vitamin digestion and absorption_Homo sapiens_hsa049770.29661075
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28610168
102FoxO signaling pathway_Homo sapiens_hsa040680.28468426
103Tryptophan metabolism_Homo sapiens_hsa003800.28345763
104HTLV-I infection_Homo sapiens_hsa051660.28102087
105Non-small cell lung cancer_Homo sapiens_hsa052230.27774332
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27435808
107Phospholipase D signaling pathway_Homo sapiens_hsa040720.26093191
108MAPK signaling pathway_Homo sapiens_hsa040100.24442318
109HIF-1 signaling pathway_Homo sapiens_hsa040660.23539556
110N-Glycan biosynthesis_Homo sapiens_hsa005100.22394997
111Type II diabetes mellitus_Homo sapiens_hsa049300.22156049
112Mineral absorption_Homo sapiens_hsa049780.21899241
113Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.21308556
114SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19820412
115Rap1 signaling pathway_Homo sapiens_hsa040150.18965553
116Bladder cancer_Homo sapiens_hsa052190.17262177
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.16688244
118PPAR signaling pathway_Homo sapiens_hsa033200.16221974
119Glycerolipid metabolism_Homo sapiens_hsa005610.16172940
120Insulin resistance_Homo sapiens_hsa049310.14589677
121Nitrogen metabolism_Homo sapiens_hsa009100.11717671

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