Rank | Gene Set | Z-score |
---|---|---|
1 | cardiac myofibril assembly (GO:0055003) | 6.05850569 |
2 | sarcomere organization (GO:0045214) | 5.90599926 |
3 | plasma membrane repair (GO:0001778) | 5.65781357 |
4 | myofibril assembly (GO:0030239) | 5.17625209 |
5 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 4.63757985 |
6 | muscle filament sliding (GO:0030049) | 4.57272232 |
7 | actin-myosin filament sliding (GO:0033275) | 4.57272232 |
8 | protein heterotrimerization (GO:0070208) | 4.39485804 |
9 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 4.30350551 |
10 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.25378079 |
11 | cardiac muscle cell development (GO:0055013) | 4.23582790 |
12 | actomyosin structure organization (GO:0031032) | 4.21835093 |
13 | regulation of skeletal muscle contraction (GO:0014819) | 4.17035449 |
14 | vascular endothelial growth factor signaling pathway (GO:0038084) | 4.09267562 |
15 | heart trabecula formation (GO:0060347) | 4.08704638 |
16 | cardiac cell development (GO:0055006) | 4.07693161 |
17 | actin-mediated cell contraction (GO:0070252) | 3.96098427 |
18 | cardiac muscle contraction (GO:0060048) | 3.95586482 |
19 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.92289976 |
20 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.85174875 |
21 | epithelial cell-cell adhesion (GO:0090136) | 3.85088750 |
22 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.68815880 |
23 | regulation of actin filament-based movement (GO:1903115) | 3.64218493 |
24 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.63335896 |
25 | collagen fibril organization (GO:0030199) | 3.59825383 |
26 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.57247682 |
27 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.54965152 |
28 | carnitine shuttle (GO:0006853) | 3.54953330 |
29 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.52926658 |
30 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.51577185 |
31 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.49548406 |
32 | basement membrane organization (GO:0071711) | 3.46350945 |
33 | regulation of cardioblast differentiation (GO:0051890) | 3.41840511 |
34 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.40962371 |
35 | renal filtration (GO:0097205) | 3.38025246 |
36 | trabecula formation (GO:0060343) | 3.37066533 |
37 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.36633756 |
38 | tricarboxylic acid cycle (GO:0006099) | 3.34314431 |
39 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.32590226 |
40 | extracellular fibril organization (GO:0043206) | 3.32191170 |
41 | glomerular filtration (GO:0003094) | 3.31917113 |
42 | actin filament-based movement (GO:0030048) | 3.31067544 |
43 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.29852977 |
44 | extracellular matrix assembly (GO:0085029) | 3.27297780 |
45 | muscle tissue morphogenesis (GO:0060415) | 3.26299125 |
46 | adult heart development (GO:0007512) | 3.25331594 |
47 | regulation of p38MAPK cascade (GO:1900744) | 3.23355407 |
48 | cell adhesion mediated by integrin (GO:0033627) | 3.21347346 |
49 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.19228548 |
50 | striated muscle hypertrophy (GO:0014897) | 3.16443842 |
51 | cardiac muscle hypertrophy (GO:0003300) | 3.14134595 |
52 | fatty acid transmembrane transport (GO:1902001) | 3.12672062 |
53 | * glomerular basement membrane development (GO:0032836) | 3.12519865 |
54 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.12080247 |
55 | axon extension involved in axon guidance (GO:0048846) | 3.10941917 |
56 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.10941917 |
57 | bone trabecula formation (GO:0060346) | 3.10742027 |
58 | cell-substrate junction assembly (GO:0007044) | 3.10508086 |
59 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.07912328 |
60 | negative regulation of fatty acid transport (GO:2000192) | 3.07434309 |
61 | regulation of relaxation of muscle (GO:1901077) | 3.07270218 |
62 | negative regulation of heart growth (GO:0061117) | 3.05197566 |
63 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 3.05197566 |
64 | atrioventricular valve morphogenesis (GO:0003181) | 3.02326194 |
65 | cardiac muscle cell proliferation (GO:0060038) | 3.02321836 |
66 | kidney mesenchyme development (GO:0072074) | 3.00500463 |
67 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.99277901 |
68 | striated muscle contraction (GO:0006941) | 2.98864090 |
69 | endodermal cell differentiation (GO:0035987) | 2.97518631 |
70 | COPI coating of Golgi vesicle (GO:0048205) | 2.96375882 |
71 | Golgi transport vesicle coating (GO:0048200) | 2.96375882 |
72 | endocardial cushion development (GO:0003197) | 2.96167166 |
73 | extracellular matrix disassembly (GO:0022617) | 2.95763993 |
74 | metanephric mesenchyme development (GO:0072075) | 2.94125025 |
75 | regulation of tight junction assembly (GO:2000810) | 2.93769383 |
76 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.93405090 |
77 | barbed-end actin filament capping (GO:0051016) | 2.93161200 |
78 | fibroblast migration (GO:0010761) | 2.91871286 |
79 | stress fiber assembly (GO:0043149) | 2.91211785 |
80 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.91156260 |
81 | collagen metabolic process (GO:0032963) | 2.90452295 |
82 | hemidesmosome assembly (GO:0031581) | 2.89707984 |
83 | regulation of striated muscle contraction (GO:0006942) | 2.89221383 |
84 | cell migration involved in heart development (GO:0060973) | 2.88370131 |
85 | fibril organization (GO:0097435) | 2.88051222 |
86 | cell communication involved in cardiac conduction (GO:0086065) | 2.87730585 |
87 | regulation of the force of heart contraction (GO:0002026) | 2.87058707 |
88 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.86780704 |
89 | apoptotic cell clearance (GO:0043277) | 2.84964618 |
90 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.84507058 |
91 | semaphorin-plexin signaling pathway (GO:0071526) | 2.84463674 |
92 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.84325217 |
93 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.83316905 |
94 | type B pancreatic cell proliferation (GO:0044342) | 2.82903987 |
95 | regulation of plasminogen activation (GO:0010755) | 2.81763675 |
96 | endothelial cell chemotaxis (GO:0035767) | 2.81158495 |
97 | adhesion of symbiont to host (GO:0044406) | 2.81103513 |
98 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.80923394 |
99 | adherens junction assembly (GO:0034333) | 2.80814885 |
100 | endothelial cell morphogenesis (GO:0001886) | 2.80533174 |
101 | collagen catabolic process (GO:0030574) | 2.80510533 |
102 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.79496304 |
103 | regulation of fatty acid oxidation (GO:0046320) | 2.75058789 |
104 | protein retention in ER lumen (GO:0006621) | 2.74981682 |
105 | skin morphogenesis (GO:0043589) | 2.74589389 |
106 | virion attachment to host cell (GO:0019062) | 2.71760499 |
107 | adhesion of symbiont to host cell (GO:0044650) | 2.71760499 |
108 | desmosome organization (GO:0002934) | 2.71527348 |
109 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.71432669 |
110 | muscle hypertrophy (GO:0014896) | 2.71359463 |
111 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.68845031 |
112 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.68375373 |
113 | heart morphogenesis (GO:0003007) | 2.67308185 |
114 | regulation of extracellular matrix disassembly (GO:0010715) | 2.67059842 |
115 | regulation of sarcomere organization (GO:0060297) | 2.67016570 |
116 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.66916547 |
117 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.66891377 |
118 | lymph vessel development (GO:0001945) | 2.65998537 |
119 | growth hormone secretion (GO:0030252) | 2.65923493 |
120 | coronary vasculature morphogenesis (GO:0060977) | 2.64962048 |
121 | focal adhesion assembly (GO:0048041) | 2.64933091 |
122 | cell-substrate adherens junction assembly (GO:0007045) | 2.64933091 |
123 | multicellular organismal catabolic process (GO:0044243) | 2.64395030 |
124 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.64338965 |
125 | multicellular organismal metabolic process (GO:0044236) | 2.64233912 |
126 | carnitine transmembrane transport (GO:1902603) | 2.63832191 |
127 | * extracellular matrix organization (GO:0030198) | 2.62813021 |
128 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.61976681 |
129 | cell communication by electrical coupling (GO:0010644) | 2.61973621 |
130 | * extracellular structure organization (GO:0043062) | 2.61782697 |
131 | lymphangiogenesis (GO:0001946) | 2.61385415 |
132 | chondrocyte proliferation (GO:0035988) | 2.60936016 |
133 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 2.60890545 |
134 | venous blood vessel morphogenesis (GO:0048845) | 2.60822690 |
135 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.60729886 |
136 | substrate-dependent cell migration (GO:0006929) | 2.59252854 |
137 | positive regulation of osteoblast proliferation (GO:0033690) | 2.59204836 |
138 | protein hydroxylation (GO:0018126) | 2.57979075 |
139 | regulation of sequestering of triglyceride (GO:0010889) | 2.56791987 |
140 | positive regulation of receptor recycling (GO:0001921) | 2.56523735 |
141 | regulation of establishment of planar polarity (GO:0090175) | 2.54855216 |
142 | negative regulation of cartilage development (GO:0061037) | 2.54294596 |
143 | regulation of apoptotic cell clearance (GO:2000425) | 2.53275003 |
144 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.51519874 |
145 | cell proliferation involved in metanephros development (GO:0072203) | 2.51475465 |
146 | wound healing, spreading of epidermal cells (GO:0035313) | 2.51021787 |
147 | paraxial mesoderm development (GO:0048339) | 2.49770526 |
148 | blood vessel maturation (GO:0001955) | 2.48084965 |
149 | negative regulation of catenin import into nucleus (GO:0035414) | 2.47102828 |
150 | keratan sulfate catabolic process (GO:0042340) | 2.46642821 |
151 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.45863881 |
152 | blood vessel endothelial cell migration (GO:0043534) | 2.44501913 |
153 | protein carboxylation (GO:0018214) | 2.39879867 |
154 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.39879867 |
155 | cochlea morphogenesis (GO:0090103) | 2.36209723 |
156 | cellular response to vitamin (GO:0071295) | 2.36187842 |
157 | muscle cell migration (GO:0014812) | 2.35799783 |
158 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.32951126 |
159 | cell-matrix adhesion (GO:0007160) | 2.32612218 |
160 | cell-substrate adhesion (GO:0031589) | 2.32567141 |
161 | protein localization to endosome (GO:0036010) | 2.32358811 |
162 | peptidyl-proline hydroxylation (GO:0019511) | 2.31730211 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.27673080 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.12060350 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.99159834 |
4 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.57043528 |
5 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 3.16855794 |
6 | CLOCK_20551151_ChIP-Seq_293T_Human | 3.16520471 |
7 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 2.58598214 |
8 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 2.58598214 |
9 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.50402605 |
10 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.43934816 |
11 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.41115195 |
12 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.39854076 |
13 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.37958435 |
14 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.28634829 |
15 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.25018015 |
16 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.17026366 |
17 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.11377846 |
18 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.11022046 |
19 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.09926210 |
20 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.95521719 |
21 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.88988999 |
22 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.82038287 |
23 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.80228405 |
24 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.79178992 |
25 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.77353503 |
26 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.74332107 |
27 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.72642937 |
28 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.69915738 |
29 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.69781773 |
30 | CJUN_26792858_Chip-Seq_BT549_Human | 1.69321632 |
31 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.60729613 |
32 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.59853042 |
33 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.56269174 |
34 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.55671955 |
35 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.53967533 |
36 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.52366013 |
37 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.50912674 |
38 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.49564490 |
39 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.49485539 |
40 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.43324690 |
41 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.41651338 |
42 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.41272461 |
43 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.41108231 |
44 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.39006855 |
45 | KDM2B_26808549_Chip-Seq_K562_Human | 1.38482442 |
46 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.38091848 |
47 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.37473522 |
48 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.37075419 |
49 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.36548834 |
50 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.35984761 |
51 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.31987496 |
52 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.31105459 |
53 | * ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.28682615 |
54 | ATF3_27146783_Chip-Seq_COLON_Human | 1.28105154 |
55 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.26787910 |
56 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.25718181 |
57 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.23673283 |
58 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.22709935 |
59 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.21040155 |
60 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.21033614 |
61 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.20401325 |
62 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.19780706 |
63 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.19541551 |
64 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.18836570 |
65 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.18836570 |
66 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.17983474 |
67 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.17103134 |
68 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.17001412 |
69 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.17001412 |
70 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.16916481 |
71 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.16615737 |
72 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.16355068 |
73 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.16145124 |
74 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.14617465 |
75 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.12590963 |
76 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.12247543 |
77 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.11315885 |
78 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.11070762 |
79 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.09993761 |
80 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09850493 |
81 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.09174976 |
82 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.08809905 |
83 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.08693932 |
84 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.08312274 |
85 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.07779246 |
86 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.07727653 |
87 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.07443949 |
88 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.07339867 |
89 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.07092419 |
90 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.06801964 |
91 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.06651922 |
92 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.05781312 |
93 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.05702080 |
94 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.05456823 |
95 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05454963 |
96 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.03431881 |
97 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.03250525 |
98 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.02941727 |
99 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02569495 |
100 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.02429367 |
101 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.02227457 |
102 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.02162975 |
103 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01991659 |
104 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.01507702 |
105 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.01167831 |
106 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.00977707 |
107 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.00829988 |
108 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.99913938 |
109 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.99842236 |
110 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.99523703 |
111 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.98777136 |
112 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.98168985 |
113 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.98149010 |
114 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.98074538 |
115 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.98051654 |
116 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.97174959 |
117 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.96275227 |
118 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.95969893 |
119 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.94938053 |
120 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.94938053 |
121 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94361602 |
122 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.94023404 |
123 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.93431030 |
124 | TP53_16413492_ChIP-PET_HCT116_Human | 0.92451538 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 4.82380798 |
2 | MP0002837_dystrophic_cardiac_calcinosis | 4.60731924 |
3 | MP0004084_abnormal_cardiac_muscle | 4.31410438 |
4 | MP0000751_myopathy | 4.08878087 |
5 | MP0005275_abnormal_skin_tensile | 3.32472500 |
6 | MP0004036_abnormal_muscle_relaxation | 3.02242594 |
7 | MP0003705_abnormal_hypodermis_morpholog | 2.95990784 |
8 | MP0004272_abnormal_basement_membrane | 2.92725461 |
9 | MP0004215_abnormal_myocardial_fiber | 2.88309879 |
10 | MP0003646_muscle_fatigue | 2.74857644 |
11 | MP0003279_aneurysm | 2.73807486 |
12 | MP0005330_cardiomyopathy | 2.71900850 |
13 | MP0000749_muscle_degeneration | 2.62818167 |
14 | MP0005503_abnormal_tendon_morphology | 2.55828049 |
15 | MP0000750_abnormal_muscle_regeneration | 2.44352860 |
16 | MP0005623_abnormal_meninges_morphology | 2.42256682 |
17 | MP0004087_abnormal_muscle_fiber | 2.35681015 |
18 | MP0001958_emphysema | 2.32565393 |
19 | MP0008775_abnormal_heart_ventricle | 2.13414610 |
20 | MP0006138_congestive_heart_failure | 2.11437077 |
21 | MP0002972_abnormal_cardiac_muscle | 2.08534946 |
22 | MP0010368_abnormal_lymphatic_system | 2.06818192 |
23 | MP0010630_abnormal_cardiac_muscle | 2.00297875 |
24 | MP0005620_abnormal_muscle_contractility | 1.94660021 |
25 | MP0001544_abnormal_cardiovascular_syste | 1.94242530 |
26 | MP0005385_cardiovascular_system_phenoty | 1.94242530 |
27 | MP0004130_abnormal_muscle_cell | 1.85065176 |
28 | MP0003566_abnormal_cell_adhesion | 1.83946367 |
29 | MP0003828_pulmonary_edema | 1.82563421 |
30 | MP0002106_abnormal_muscle_physiology | 1.70989235 |
31 | MP0003137_abnormal_impulse_conducting | 1.67071034 |
32 | MP0009384_cardiac_valve_regurgitation | 1.64638729 |
33 | MP0002269_muscular_atrophy | 1.64608320 |
34 | MP0004484_altered_response_of | 1.59299732 |
35 | MP0000759_abnormal_skeletal_muscle | 1.56755246 |
36 | MP0005670_abnormal_white_adipose | 1.56651044 |
37 | MP0004145_abnormal_muscle_electrophysio | 1.55352518 |
38 | MP0005369_muscle_phenotype | 1.55307775 |
39 | MP0005666_abnormal_adipose_tissue | 1.55081825 |
40 | MP0002108_abnormal_muscle_morphology | 1.54744522 |
41 | MP0001879_abnormal_lymphatic_vessel | 1.51568070 |
42 | MP0006054_spinal_hemorrhage | 1.51233857 |
43 | MP0001849_ear_inflammation | 1.48983449 |
44 | MP0000747_muscle_weakness | 1.45507269 |
45 | MP0004185_abnormal_adipocyte_glucose | 1.40336750 |
46 | MP0004233_abnormal_muscle_weight | 1.39713544 |
47 | MP0000013_abnormal_adipose_tissue | 1.37924189 |
48 | MP0000767_abnormal_smooth_muscle | 1.37556108 |
49 | MP0001542_abnormal_bone_strength | 1.36022374 |
50 | MP0005409_darkened_coat_color | 1.34194240 |
51 | MP0005058_abnormal_lysosome_morphology | 1.32973111 |
52 | MP0005375_adipose_tissue_phenotype | 1.28193490 |
53 | MP0000733_abnormal_muscle_development | 1.27845456 |
54 | MP0004085_abnormal_heartbeat | 1.26383155 |
55 | MP0002295_abnormal_pulmonary_circulatio | 1.26031962 |
56 | MP0003950_abnormal_plasma_membrane | 1.20924527 |
57 | MP0003045_fibrosis | 1.16432977 |
58 | MP0003091_abnormal_cell_migration | 1.13933211 |
59 | MP0002128_abnormal_blood_circulation | 1.11739114 |
60 | MP0009840_abnormal_foam_cell | 1.10914929 |
61 | MP0005508_abnormal_skeleton_morphology | 1.10842652 |
62 | MP0000762_abnormal_tongue_morphology | 1.10698668 |
63 | MP0000343_altered_response_to | 1.10120892 |
64 | MP0002254_reproductive_system_inflammat | 1.09688580 |
65 | MP0000003_abnormal_adipose_tissue | 1.08988872 |
66 | MP0000266_abnormal_heart_morphology | 1.07558217 |
67 | MP0001243_abnormal_dermal_layer | 1.06814138 |
68 | MP0002127_abnormal_cardiovascular_syste | 1.03924500 |
69 | MP0005171_absent_coat_pigmentation | 1.03468584 |
70 | MP0002060_abnormal_skin_morphology | 1.03113913 |
71 | MP0005165_increased_susceptibility_to | 1.00993953 |
72 | MP0002234_abnormal_pharynx_morphology | 1.00349565 |
73 | MP0003567_abnormal_fetal_cardiomyocyte | 0.99808525 |
74 | MP0005023_abnormal_wound_healing | 0.97118528 |
75 | MP0002933_joint_inflammation | 0.95536881 |
76 | MP0001348_abnormal_lacrimal_gland | 0.92019713 |
77 | MP0005167_abnormal_blood-brain_barrier | 0.91615756 |
78 | MP0002896_abnormal_bone_mineralization | 0.90806553 |
79 | MP0003283_abnormal_digestive_organ | 0.89514293 |
80 | MP0001915_intracranial_hemorrhage | 0.89443569 |
81 | MP0000462_abnormal_digestive_system | 0.89252679 |
82 | MP0002925_abnormal_cardiovascular_devel | 0.88054401 |
83 | MP0000534_abnormal_ureter_morphology | 0.87662046 |
84 | MP0003385_abnormal_body_wall | 0.85488949 |
85 | MP0001614_abnormal_blood_vessel | 0.85342708 |
86 | MP0001661_extended_life_span | 0.84726565 |
87 | MP0003221_abnormal_cardiomyocyte_apopto | 0.83470220 |
88 | MP0009780_abnormal_chondrocyte_physiolo | 0.83377355 |
89 | MP0010030_abnormal_orbit_morphology | 0.82230014 |
90 | MP0005257_abnormal_intraocular_pressure | 0.80996802 |
91 | MP0005390_skeleton_phenotype | 0.80571848 |
92 | MP0002932_abnormal_joint_morphology | 0.79689317 |
93 | MP0003191_abnormal_cellular_cholesterol | 0.79098051 |
94 | MP0002089_abnormal_postnatal_growth/wei | 0.78089468 |
95 | MP0000467_abnormal_esophagus_morphology | 0.76323980 |
96 | MP0002115_abnormal_skeleton_extremities | 0.75860671 |
97 | MP0000537_abnormal_urethra_morphology | 0.75706694 |
98 | MP0010352_gastrointestinal_tract_polyps | 0.73692057 |
99 | MP0004510_myositis | 0.73335204 |
100 | MP0003115_abnormal_respiratory_system | 0.73086614 |
101 | MP0009053_abnormal_anal_canal | 0.71987269 |
102 | MP0003941_abnormal_skin_development | 0.70841908 |
103 | MP0002332_abnormal_exercise_endurance | 0.70837044 |
104 | MP0005197_abnormal_uvea_morphology | 0.70518275 |
105 | MP0005595_abnormal_vascular_smooth | 0.69727780 |
106 | MP0002168_other_aberrant_phenotype | 0.69555648 |
107 | MP0002113_abnormal_skeleton_development | 0.68284585 |
108 | MP0001299_abnormal_eye_distance/ | 0.68054943 |
109 | MP0000230_abnormal_systemic_arterial | 0.67270396 |
110 | MP0002116_abnormal_craniofacial_bone | 0.67170677 |
111 | MP0009250_abnormal_appendicular_skeleto | 0.67099926 |
112 | MP0000428_abnormal_craniofacial_morphol | 0.67007265 |
113 | MP0005164_abnormal_response_to | 0.66176704 |
114 | MP0000566_synostosis | 0.65921510 |
115 | MP0002877_abnormal_melanocyte_morpholog | 0.65557332 |
116 | MP0003942_abnormal_urinary_system | 0.63557998 |
117 | MP0009278_abnormal_bone_marrow | 0.61414571 |
118 | MP0005076_abnormal_cell_differentiation | 0.60734222 |
119 | MP0003300_gastrointestinal_ulcer | 0.59456046 |
120 | MP0002133_abnormal_respiratory_system | 0.59393142 |
121 | MP0005388_respiratory_system_phenotype | 0.59393142 |
122 | MP0003935_abnormal_craniofacial_develop | 0.58198508 |
123 | MP0000163_abnormal_cartilage_morphology | 0.55841840 |
124 | MP0002249_abnormal_larynx_morphology | 0.55295136 |
125 | MP0001784_abnormal_fluid_regulation | 0.54419224 |
126 | MP0004858_abnormal_nervous_system | 0.52726276 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 5.21503072 |
2 | Muscle fiber splitting (HP:0003555) | 5.15827492 |
3 | Increased connective tissue (HP:0009025) | 5.06793950 |
4 | Protrusio acetabuli (HP:0003179) | 4.97844682 |
5 | Premature rupture of membranes (HP:0001788) | 4.88822766 |
6 | Ventricular tachycardia (HP:0004756) | 4.71172071 |
7 | Ankle contracture (HP:0006466) | 4.38512151 |
8 | Hyporeflexia of lower limbs (HP:0002600) | 4.37365745 |
9 | Broad metatarsal (HP:0001783) | 4.36673801 |
10 | Right ventricular cardiomyopathy (HP:0011663) | 4.34600571 |
11 | Type 1 muscle fiber predominance (HP:0003803) | 4.06872174 |
12 | Atrial fibrillation (HP:0005110) | 3.92511595 |
13 | Lipoatrophy (HP:0100578) | 3.89262428 |
14 | Abnormality of the calf musculature (HP:0001430) | 3.88569211 |
15 | Calf muscle hypertrophy (HP:0008981) | 3.83858596 |
16 | Cerebral aneurysm (HP:0004944) | 3.83601001 |
17 | Aortic dissection (HP:0002647) | 3.73038939 |
18 | Exercise-induced muscle cramps (HP:0003710) | 3.72392306 |
19 | Primary atrial arrhythmia (HP:0001692) | 3.66777675 |
20 | Increased variability in muscle fiber diameter (HP:0003557) | 3.64517106 |
21 | Arterial tortuosity (HP:0005116) | 3.61564381 |
22 | Exercise-induced myalgia (HP:0003738) | 3.59878418 |
23 | Supraventricular arrhythmia (HP:0005115) | 3.56256536 |
24 | Supraventricular tachycardia (HP:0004755) | 3.49107701 |
25 | Difficulty running (HP:0009046) | 3.48889131 |
26 | Shallow orbits (HP:0000586) | 3.41831922 |
27 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.41622450 |
28 | Aortic aneurysm (HP:0004942) | 3.31229359 |
29 | Abnormality of skeletal muscle fiber size (HP:0012084) | 3.24851554 |
30 | Difficulty climbing stairs (HP:0003551) | 3.23017507 |
31 | Mildly elevated creatine phosphokinase (HP:0008180) | 3.12128347 |
32 | Spinal rigidity (HP:0003306) | 3.08599875 |
33 | Subaortic stenosis (HP:0001682) | 3.06539403 |
34 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.06539403 |
35 | EMG: myopathic abnormalities (HP:0003458) | 2.99902602 |
36 | Vertebral compression fractures (HP:0002953) | 2.99843488 |
37 | Atrophic scars (HP:0001075) | 2.94022584 |
38 | Bundle branch block (HP:0011710) | 2.92953599 |
39 | Asymmetric septal hypertrophy (HP:0001670) | 2.91808979 |
40 | Dilated cardiomyopathy (HP:0001644) | 2.91472943 |
41 | Bladder diverticulum (HP:0000015) | 2.85556877 |
42 | Biconcave vertebral bodies (HP:0004586) | 2.83466849 |
43 | Myoglobinuria (HP:0002913) | 2.80343932 |
44 | Syncope (HP:0001279) | 2.73906324 |
45 | Aneurysm (HP:0002617) | 2.68199873 |
46 | Fragile skin (HP:0001030) | 2.66575208 |
47 | Prolonged QT interval (HP:0001657) | 2.65830059 |
48 | Soft skin (HP:0000977) | 2.65645160 |
49 | Ulnar bowing (HP:0003031) | 2.60597787 |
50 | Mitral valve prolapse (HP:0001634) | 2.57911922 |
51 | Ventricular arrhythmia (HP:0004308) | 2.56613394 |
52 | Myotonia (HP:0002486) | 2.55816260 |
53 | Mitral regurgitation (HP:0001653) | 2.51477798 |
54 | Lymphangioma (HP:0100764) | 2.48348976 |
55 | Atrioventricular block (HP:0001678) | 2.46657724 |
56 | Wrist flexion contracture (HP:0001239) | 2.43776753 |
57 | Abnormal atrioventricular conduction (HP:0005150) | 2.43646289 |
58 | Hypoplastic ischia (HP:0003175) | 2.42469864 |
59 | Dilatation of the ascending aorta (HP:0005111) | 2.41667100 |
60 | Scapular winging (HP:0003691) | 2.41242243 |
61 | Aortic regurgitation (HP:0001659) | 2.40532542 |
62 | Mitral stenosis (HP:0001718) | 2.40043313 |
63 | Heart block (HP:0012722) | 2.38308361 |
64 | Palpitations (HP:0001962) | 2.35701020 |
65 | Follicular hyperkeratosis (HP:0007502) | 2.31746308 |
66 | Bowel diverticulosis (HP:0005222) | 2.31452016 |
67 | Abnormality of the acetabulum (HP:0003170) | 2.25582454 |
68 | Abnormal delivery (HP:0001787) | 2.23556093 |
69 | Joint stiffness (HP:0001387) | 2.20922460 |
70 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.19633885 |
71 | Osteolytic defects of the hand bones (HP:0009699) | 2.19633885 |
72 | Round ear (HP:0100830) | 2.16745806 |
73 | Limb-girdle muscle atrophy (HP:0003797) | 2.16347800 |
74 | Distal lower limb muscle weakness (HP:0009053) | 2.13951306 |
75 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.13778858 |
76 | Pulmonary artery stenosis (HP:0004415) | 2.13513873 |
77 | Facial diplegia (HP:0001349) | 2.11361832 |
78 | Peritonitis (HP:0002586) | 2.11266495 |
79 | Abnormality of the ischium (HP:0003174) | 2.10867859 |
80 | Short nail (HP:0001799) | 2.10553135 |
81 | Spondylolisthesis (HP:0003302) | 2.06474660 |
82 | Distal lower limb amyotrophy (HP:0008944) | 2.05789974 |
83 | Ventricular fibrillation (HP:0001663) | 2.05585797 |
84 | Ectopia lentis (HP:0001083) | 2.05101016 |
85 | Hip contracture (HP:0003273) | 2.04145449 |
86 | Limb-girdle muscle weakness (HP:0003325) | 2.03924548 |
87 | Cervical subluxation (HP:0003308) | 2.02485649 |
88 | Infantile muscular hypotonia (HP:0008947) | 2.01674743 |
89 | Blue sclerae (HP:0000592) | 1.99685945 |
90 | Rectal prolapse (HP:0002035) | 1.97491763 |
91 | Thin bony cortex (HP:0002753) | 1.97027976 |
92 | Wormian bones (HP:0002645) | 1.96703974 |
93 | Aortic valve stenosis (HP:0001650) | 1.96524366 |
94 | Rhabdomyolysis (HP:0003201) | 1.96506967 |
95 | Hyperacusis (HP:0010780) | 1.96425385 |
96 | Broad face (HP:0000283) | 1.96164245 |
97 | Coronal craniosynostosis (HP:0004440) | 1.96048607 |
98 | Neonatal short-limb short stature (HP:0008921) | 1.95453026 |
99 | Natal tooth (HP:0000695) | 1.93005547 |
100 | Disproportionate tall stature (HP:0001519) | 1.92483369 |
101 | Slender build (HP:0001533) | 1.91253082 |
102 | Coxa vara (HP:0002812) | 1.91061816 |
103 | Abnormality of dentin (HP:0010299) | 1.90521546 |
104 | Osteoarthritis (HP:0002758) | 1.88589611 |
105 | Hyperextensible skin (HP:0000974) | 1.87776789 |
106 | Generalized amyotrophy (HP:0003700) | 1.87715912 |
107 | Limited hip movement (HP:0008800) | 1.87011101 |
108 | Genu recurvatum (HP:0002816) | 1.85569844 |
109 | Breech presentation (HP:0001623) | 1.84099515 |
110 | Testicular atrophy (HP:0000029) | 1.83509796 |
111 | Muscular dystrophy (HP:0003560) | 1.81987598 |
112 | Vascular tortuosity (HP:0004948) | 1.80917089 |
113 | Short hallux (HP:0010109) | 1.80290608 |
114 | Overgrowth (HP:0001548) | 1.79851106 |
115 | Venous abnormality (HP:0002624) | 1.79315890 |
116 | Abnormality of the 4th metacarpal (HP:0010012) | 1.79201427 |
117 | Camptodactyly of toe (HP:0001836) | 1.78248580 |
118 | Turricephaly (HP:0000262) | 1.77389989 |
119 | Neck muscle weakness (HP:0000467) | 1.77317281 |
120 | Ulnar deviation of the wrist (HP:0003049) | 1.77036609 |
121 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.76970950 |
122 | Inguinal hernia (HP:0000023) | 1.76606974 |
123 | Abnormality of complement system (HP:0005339) | 1.75757656 |
124 | Abnormality of carpal bone ossification (HP:0006257) | 1.75460898 |
125 | Nonimmune hydrops fetalis (HP:0001790) | 1.74742771 |
126 | Wide anterior fontanel (HP:0000260) | 1.73533362 |
127 | Deep venous thrombosis (HP:0002625) | 1.72838519 |
128 | Elbow flexion contracture (HP:0002987) | 1.72789221 |
129 | Knee flexion contracture (HP:0006380) | 1.72420642 |
130 | Advanced eruption of teeth (HP:0006288) | 1.71983697 |
131 | Mild short stature (HP:0003502) | 1.71709725 |
132 | Abnormal EKG (HP:0003115) | 1.71562377 |
133 | Upper limb amyotrophy (HP:0009129) | 1.71318424 |
134 | Distal upper limb amyotrophy (HP:0007149) | 1.71318424 |
135 | Abnormal ossification of hand bones (HP:0005921) | 1.70960485 |
136 | Muscle fiber inclusion bodies (HP:0100299) | 1.70481767 |
137 | Long toe (HP:0010511) | 1.70405649 |
138 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.70108795 |
139 | Joint laxity (HP:0001388) | 1.69669463 |
140 | Obstructive sleep apnea (HP:0002870) | 1.69385394 |
141 | Hypoventilation (HP:0002791) | 1.69224504 |
142 | Ovoid vertebral bodies (HP:0003300) | 1.68309292 |
143 | Achilles tendon contracture (HP:0001771) | 1.68192155 |
144 | Cupped ribs (HP:0000887) | 1.67695844 |
145 | Cardiovascular calcification (HP:0011915) | 1.66102985 |
146 | Complement deficiency (HP:0004431) | 1.64710430 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 5.80785721 |
2 | TRIB3 | 4.14918582 |
3 | MYLK | 3.37025658 |
4 | LMTK2 | 3.08251834 |
5 | PKN2 | 2.91081359 |
6 | TIE1 | 2.74940139 |
7 | DMPK | 2.67061020 |
8 | PDGFRA | 2.63260710 |
9 | RIPK1 | 2.35330439 |
10 | PHKG2 | 2.33158224 |
11 | PHKG1 | 2.33158224 |
12 | DDR2 | 2.26868162 |
13 | PDK4 | 2.07566453 |
14 | PDK3 | 2.07566453 |
15 | EPHB2 | 2.06620870 |
16 | SIK1 | 2.03948033 |
17 | OBSCN | 2.01633913 |
18 | TGFBR2 | 2.00601216 |
19 | LATS1 | 1.80576275 |
20 | TESK1 | 1.69145530 |
21 | PDK2 | 1.56590743 |
22 | ERN1 | 1.54138815 |
23 | MAP3K6 | 1.43900696 |
24 | MST1R | 1.43278250 |
25 | PAK3 | 1.40297110 |
26 | PIK3CA | 1.39778009 |
27 | SMG1 | 1.31521702 |
28 | PTK6 | 1.31048060 |
29 | FER | 1.28356838 |
30 | LATS2 | 1.27360280 |
31 | AKT3 | 1.20933150 |
32 | PAK2 | 1.19394760 |
33 | ROCK1 | 1.18865762 |
34 | EPHB1 | 1.18127196 |
35 | KDR | 1.17148216 |
36 | BCKDK | 1.16552272 |
37 | ILK | 1.15505348 |
38 | PRKD1 | 1.14950098 |
39 | LIMK1 | 1.12459633 |
40 | CAMK1D | 1.09146838 |
41 | PAK4 | 1.08380123 |
42 | EEF2K | 1.08304760 |
43 | WNK4 | 1.06048230 |
44 | MAPKAPK3 | 1.03775549 |
45 | NEK1 | 1.02982497 |
46 | TRPM7 | 0.99886357 |
47 | ICK | 0.98356674 |
48 | PTK2B | 0.97100497 |
49 | LRRK2 | 0.94538890 |
50 | CDC42BPA | 0.90565077 |
51 | MOS | 0.89097182 |
52 | MTOR | 0.88709531 |
53 | PDGFRB | 0.86235122 |
54 | CAMK1G | 0.85453585 |
55 | ERBB4 | 0.84292828 |
56 | PTK2 | 0.84192503 |
57 | MAP3K3 | 0.81614064 |
58 | MAPK7 | 0.80892901 |
59 | BMX | 0.79829010 |
60 | MARK2 | 0.79412256 |
61 | MAP2K3 | 0.77934503 |
62 | ROCK2 | 0.76984945 |
63 | PRKD3 | 0.75634693 |
64 | MAP3K7 | 0.75374467 |
65 | STK38L | 0.73866889 |
66 | MET | 0.71931920 |
67 | FGFR4 | 0.66894489 |
68 | STK24 | 0.66085220 |
69 | ABL2 | 0.65811936 |
70 | MAP3K10 | 0.65352700 |
71 | DAPK3 | 0.61809251 |
72 | PRKAA2 | 0.59893940 |
73 | EPHA3 | 0.59510975 |
74 | PRPF4B | 0.59453391 |
75 | TGFBR1 | 0.59269621 |
76 | WNK1 | 0.58990346 |
77 | FGFR1 | 0.58490560 |
78 | MAPK12 | 0.56208028 |
79 | FGFR2 | 0.55514111 |
80 | NTRK1 | 0.52737830 |
81 | EPHA2 | 0.52445201 |
82 | STK38 | 0.52348276 |
83 | PRKAA1 | 0.52250261 |
84 | CAMK2D | 0.52100182 |
85 | RET | 0.51604923 |
86 | PDPK1 | 0.49709941 |
87 | CAMK2G | 0.49185207 |
88 | PRKCH | 0.48303038 |
89 | STK39 | 0.47955204 |
90 | PINK1 | 0.47855284 |
91 | NEK9 | 0.47734784 |
92 | STK3 | 0.47270751 |
93 | MAP2K1 | 0.46785029 |
94 | TYRO3 | 0.46516249 |
95 | MUSK | 0.45016978 |
96 | FLT3 | 0.44873166 |
97 | PRKD2 | 0.43576951 |
98 | DYRK1B | 0.42726933 |
99 | RPS6KC1 | 0.42317931 |
100 | RPS6KL1 | 0.42317931 |
101 | CAMK4 | 0.41537405 |
102 | CDK12 | 0.40471151 |
103 | MAPK15 | 0.40444982 |
104 | PRKG2 | 0.40136948 |
105 | FGFR3 | 0.39150505 |
106 | IRAK3 | 0.37118640 |
107 | KSR2 | 0.36501102 |
108 | RPS6KA6 | 0.35373373 |
109 | MAPK4 | 0.34431607 |
110 | JAK1 | 0.34408734 |
111 | MELK | 0.33493406 |
112 | AKT2 | 0.33069110 |
113 | STK4 | 0.32088154 |
114 | ERBB2 | 0.31087496 |
115 | RPS6KA2 | 0.30931472 |
116 | ZAP70 | 0.29913992 |
117 | PRKACB | 0.29303624 |
118 | PIK3CG | 0.28047050 |
119 | PRKCE | 0.27801078 |
120 | HIPK2 | 0.27702237 |
121 | PIM2 | 0.27640790 |
122 | GSK3A | 0.27262012 |
123 | PAK6 | 0.27214738 |
124 | SRC | 0.26094258 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 3.82498376 |
2 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.67724329 |
3 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.61100104 |
4 | * ECM-receptor interaction_Homo sapiens_hsa04512 | 3.13588161 |
5 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.97507463 |
6 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.87750367 |
7 | * Focal adhesion_Homo sapiens_hsa04510 | 2.53257198 |
8 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.48121510 |
9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.30230713 |
10 | Other glycan degradation_Homo sapiens_hsa00511 | 2.04048102 |
11 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.01745877 |
12 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.01121438 |
13 | Viral myocarditis_Homo sapiens_hsa05416 | 1.91371798 |
14 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.88620555 |
15 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.77545579 |
16 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.75403968 |
17 | Adherens junction_Homo sapiens_hsa04520 | 1.69587996 |
18 | * Amoebiasis_Homo sapiens_hsa05146 | 1.57363046 |
19 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.57214330 |
20 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.53533102 |
21 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.49634662 |
22 | Prion diseases_Homo sapiens_hsa05020 | 1.48412082 |
23 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.44114701 |
24 | Carbon metabolism_Homo sapiens_hsa01200 | 1.39133331 |
25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.35399906 |
26 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.35301384 |
27 | Tight junction_Homo sapiens_hsa04530 | 1.33989553 |
28 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.33221341 |
29 | Insulin resistance_Homo sapiens_hsa04931 | 1.32360863 |
30 | * Small cell lung cancer_Homo sapiens_hsa05222 | 1.28241498 |
31 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.25857543 |
32 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.13746384 |
33 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.12624894 |
34 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.09758889 |
35 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.08718220 |
36 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.04250402 |
37 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.02983975 |
38 | Lysine degradation_Homo sapiens_hsa00310 | 1.01886076 |
39 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.00960841 |
40 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.00485555 |
41 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.00236790 |
42 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.99818377 |
43 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.98877108 |
44 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.98720371 |
45 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.97838199 |
46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.96548528 |
47 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.95142382 |
48 | Bladder cancer_Homo sapiens_hsa05219 | 0.94483605 |
49 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.93903723 |
50 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.93566411 |
51 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.89667442 |
52 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.89177368 |
53 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.88027320 |
54 | Galactose metabolism_Homo sapiens_hsa00052 | 0.87537276 |
55 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.86589001 |
56 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.86402167 |
57 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.86065356 |
58 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.85523219 |
59 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.81073392 |
60 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.79817693 |
61 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.79316480 |
62 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.76795946 |
63 | Lysosome_Homo sapiens_hsa04142 | 0.76365279 |
64 | Platelet activation_Homo sapiens_hsa04611 | 0.75601441 |
65 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.75284053 |
66 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.74154342 |
67 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.70897439 |
68 | * Pathways in cancer_Homo sapiens_hsa05200 | 0.69968227 |
69 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.68059990 |
70 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.66574397 |
71 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.66450300 |
72 | Melanoma_Homo sapiens_hsa05218 | 0.66190133 |
73 | Renin secretion_Homo sapiens_hsa04924 | 0.65609733 |
74 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.65598995 |
75 | Thyroid cancer_Homo sapiens_hsa05216 | 0.64841214 |
76 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.64601949 |
77 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.64256938 |
78 | Axon guidance_Homo sapiens_hsa04360 | 0.64253777 |
79 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.64062844 |
80 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.62889959 |
81 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.60982601 |
82 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.60705238 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.60215297 |
84 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.59576836 |
85 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.58788737 |
86 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.58015099 |
87 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.57505071 |
88 | Gap junction_Homo sapiens_hsa04540 | 0.57404003 |
89 | Glioma_Homo sapiens_hsa05214 | 0.56630406 |
90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.54910666 |
91 | Parkinsons disease_Homo sapiens_hsa05012 | 0.54731151 |
92 | Melanogenesis_Homo sapiens_hsa04916 | 0.54312410 |
93 | * Toxoplasmosis_Homo sapiens_hsa05145 | 0.53762030 |
94 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.52117396 |
95 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.51823893 |
96 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.51692233 |
97 | Endometrial cancer_Homo sapiens_hsa05213 | 0.50805788 |
98 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50474284 |
99 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50136023 |
100 | Endocytosis_Homo sapiens_hsa04144 | 0.49624979 |
101 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.49069781 |
102 | Alzheimers disease_Homo sapiens_hsa05010 | 0.48777687 |
103 | Malaria_Homo sapiens_hsa05144 | 0.47674573 |
104 | Histidine metabolism_Homo sapiens_hsa00340 | 0.46640786 |
105 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46627314 |
106 | Pertussis_Homo sapiens_hsa05133 | 0.46377680 |
107 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45820929 |
108 | ABC transporters_Homo sapiens_hsa02010 | 0.45815095 |
109 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.45199394 |
110 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.44767696 |
111 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.44545771 |
112 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.43247957 |
113 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.43117524 |
114 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.43073056 |
115 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.42322328 |
116 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.41955114 |
117 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.41713250 |
118 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.40495037 |
119 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.40489294 |
120 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.39575978 |
121 | Prostate cancer_Homo sapiens_hsa05215 | 0.38850359 |
122 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.36086288 |
123 | HTLV-I infection_Homo sapiens_hsa05166 | 0.36049346 |
124 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.35053983 |
125 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.34128215 |
126 | Bile secretion_Homo sapiens_hsa04976 | 0.33316222 |