LAMTOR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrocyte maturation (GO:0043249)9.08721623
2mitochondrial calcium ion homeostasis (GO:0051560)8.23180001
3UV protection (GO:0009650)7.65723020
4myelin assembly (GO:0032288)6.99429983
5hematopoietic stem cell differentiation (GO:0060218)6.73291188
6organelle membrane fusion (GO:0090174)6.24422177
7nucleotide-excision repair, DNA damage removal (GO:0000718)6.21301742
8DNA excision (GO:0044349)6.21301742
97-methylguanosine mRNA capping (GO:0006370)6.06531604
10spinal cord development (GO:0021510)6.03978526
11regulation of early endosome to late endosome transport (GO:2000641)5.89354471
127-methylguanosine RNA capping (GO:0009452)5.82977729
13RNA capping (GO:0036260)5.82977729
14termination of RNA polymerase I transcription (GO:0006363)5.54101990
15hair cell differentiation (GO:0035315)5.09843847
16deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.93782823
17ATP synthesis coupled proton transport (GO:0015986)4.84515571
18energy coupled proton transport, down electrochemical gradient (GO:0015985)4.84515571
19negative regulation of organelle assembly (GO:1902116)4.79829785
20transcription-coupled nucleotide-excision repair (GO:0006283)4.79067609
21negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.75228310
22transcription elongation from RNA polymerase I promoter (GO:0006362)4.57456784
23mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.43176629
24sequestering of actin monomers (GO:0042989)4.31499996
25transcription from RNA polymerase I promoter (GO:0006360)4.30179213
26protein neddylation (GO:0045116)4.28854564
27negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)4.26826219
28protein maturation by protein folding (GO:0022417)4.25002386
29neuronal ion channel clustering (GO:0045161)4.20985801
30transcription initiation from RNA polymerase I promoter (GO:0006361)4.17331175
31negative regulation of catenin import into nucleus (GO:0035414)4.13584593
32viral transcription (GO:0019083)3.98288517
33aldehyde catabolic process (GO:0046185)3.97561835
34positive regulation of viral transcription (GO:0050434)3.95645941
35translational termination (GO:0006415)3.75295887
36DNA damage response, detection of DNA damage (GO:0042769)3.73260635
37lipoxygenase pathway (GO:0019372)3.66082613
38ribosomal small subunit biogenesis (GO:0042274)3.66008206
39SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.64536091
40cotranslational protein targeting to membrane (GO:0006613)3.60307204
41protein targeting to ER (GO:0045047)3.59403821
42neutrophil activation involved in immune response (GO:0002283)3.56296055
43ribosomal small subunit assembly (GO:0000028)3.52690229
44antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.46386684
45telomere maintenance via semi-conservative replication (GO:0032201)3.45107674
46antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.43881438
47establishment of protein localization to endoplasmic reticulum (GO:0072599)3.42368863
48protein localization to endoplasmic reticulum (GO:0070972)3.41226573
49positive regulation of B cell differentiation (GO:0045579)3.38668818
50proteasome assembly (GO:0043248)3.36831839
51negative regulation of epithelial to mesenchymal transition (GO:0010719)3.33937218
52transcription elongation from RNA polymerase II promoter (GO:0006368)3.30239116
53positive regulation of DNA binding (GO:0043388)3.27596056
54translational elongation (GO:0006414)3.26970292
55L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.26303604
56pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.24531327
57autophagic vacuole fusion (GO:0000046)3.24162472
58deoxyribonucleotide catabolic process (GO:0009264)3.23117762
59negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.22971724
60maturation of SSU-rRNA (GO:0030490)3.20228842
61response to peptidoglycan (GO:0032494)3.17522248
62platelet aggregation (GO:0070527)3.15877363
63deoxyribose phosphate catabolic process (GO:0046386)3.13741050
64regulation of mast cell degranulation (GO:0043304)3.13435152
65execution phase of apoptosis (GO:0097194)3.13207101
66regulation of superoxide anion generation (GO:0032928)3.12967410
67negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.12843327
68positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.12630523
69anatomical structure maturation (GO:0071695)3.10688378
70mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.10388079
71respiratory electron transport chain (GO:0022904)3.08626050
72neutrophil activation (GO:0042119)3.06043170
73purine nucleotide salvage (GO:0032261)3.04283894
74GTP biosynthetic process (GO:0006183)3.02367529
75electron transport chain (GO:0022900)3.02177282
76pentose-phosphate shunt (GO:0006098)3.00853659
77pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.99083710
78immunoglobulin mediated immune response (GO:0016064)2.97027675
79viral life cycle (GO:0019058)2.96603114
80pinocytosis (GO:0006907)2.96492466
81thrombin receptor signaling pathway (GO:0070493)2.95995478
82purine-containing compound salvage (GO:0043101)2.95402457
83respiratory burst (GO:0045730)2.95105214
84regulation of platelet aggregation (GO:0090330)2.94641273
85translational initiation (GO:0006413)2.93828710
86cellular protein complex disassembly (GO:0043624)2.92610790
87telomere maintenance via recombination (GO:0000722)2.92429387
88positive regulation of mast cell activation (GO:0033005)2.92235410
89negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.91884210
90negative regulation of ligase activity (GO:0051352)2.91884210
91granulocyte activation (GO:0036230)2.89065942
92DNA strand elongation involved in DNA replication (GO:0006271)2.88127820
93angiogenesis involved in wound healing (GO:0060055)2.87521228
94mitochondrial transport (GO:0006839)2.87245841
95regulation of integrin-mediated signaling pathway (GO:2001044)2.86488919
96phagosome maturation (GO:0090382)2.84888766
97nucleotide-excision repair (GO:0006289)2.83485820
98pyrimidine nucleoside salvage (GO:0043097)2.82652125
99pyrimidine-containing compound salvage (GO:0008655)2.82652125
100purine deoxyribonucleotide catabolic process (GO:0009155)2.82284756
101DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.81363014
102nucleoside salvage (GO:0043174)2.80544867
103response to dietary excess (GO:0002021)2.80425626
104translation (GO:0006412)2.79564351
105regulation of mast cell activation involved in immune response (GO:0033006)2.79151518
106ribosomal large subunit biogenesis (GO:0042273)2.79032394
107modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.78843200
108positive regulation by organism of defense response of other organism involved in symbiotic interact2.78843200
109modulation by symbiont of host immune response (GO:0052553)2.78843200
110positive regulation by symbiont of host defense response (GO:0052509)2.78843200
111modulation by symbiont of host defense response (GO:0052031)2.78843200
112modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.78843200
113NADPH regeneration (GO:0006740)2.78002878
114positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.75674408
115protein targeting to mitochondrion (GO:0006626)2.73705478
116DNA deamination (GO:0045006)2.73680874
117Arp2/3 complex-mediated actin nucleation (GO:0034314)2.73398301
118pentose metabolic process (GO:0019321)2.73359687
119regulation of cellular amino acid metabolic process (GO:0006521)2.72664282
120DNA strand elongation (GO:0022616)2.72601419
121L-methionine salvage (GO:0071267)2.72173632
122L-methionine biosynthetic process (GO:0071265)2.72173632
123amino acid salvage (GO:0043102)2.72173632
124regulation of viral transcription (GO:0046782)2.71961475
125B cell mediated immunity (GO:0019724)2.71840932
126extracellular fibril organization (GO:0043206)2.70548531
127intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.70386566
128signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.70386566
129negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.70339072
130hydrogen peroxide catabolic process (GO:0042744)2.69908474
131protein complex biogenesis (GO:0070271)2.69846218
132nucleotide-excision repair, DNA gap filling (GO:0006297)2.68960250
133UTP biosynthetic process (GO:0006228)2.68907180
134signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.68697457
135signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.68697457
136signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.68697457
137antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.68392890
138regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.67840970
139establishment of protein localization to mitochondrion (GO:0072655)2.67762714
140chaperone-mediated protein transport (GO:0072321)2.67751744
141positive regulation of mast cell degranulation (GO:0043306)2.66816955
142positive regulation of mast cell activation involved in immune response (GO:0033008)2.66816955
143regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803)2.65281420
144mitochondrion morphogenesis (GO:0070584)2.64962583
145amino sugar catabolic process (GO:0046348)2.64900701
146negative regulation of fibroblast apoptotic process (GO:2000270)2.64786421
147adenosine receptor signaling pathway (GO:0001973)2.64066289
148negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.63496472
149deoxyribose phosphate biosynthetic process (GO:0046385)2.63472021
1502-deoxyribonucleotide biosynthetic process (GO:0009265)2.63472021
151anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.63421400
152positive regulation of viral process (GO:0048524)2.62857890
153establishment of mitochondrion localization (GO:0051654)2.62242697
154regulation of platelet activation (GO:0010543)2.61454015
155nucleotide salvage (GO:0043173)2.61224682
156cyclooxygenase pathway (GO:0019371)2.58231250
157leukocyte migration involved in inflammatory response (GO:0002523)2.56954743
158pyrimidine nucleotide catabolic process (GO:0006244)2.56561718
159response to interferon-beta (GO:0035456)2.53842968
160fibril organization (GO:0097435)2.53480565
161regulation of myeloid leukocyte mediated immunity (GO:0002886)2.53405161
162glucose catabolic process (GO:0006007)2.51748179
163deoxyribose phosphate metabolic process (GO:0019692)2.51330300
164mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.47649642
165mitochondrial respiratory chain complex I assembly (GO:0032981)2.47649642
166NADH dehydrogenase complex assembly (GO:0010257)2.47649642
167leukocyte degranulation (GO:0043299)2.47640364
168regulation of superoxide metabolic process (GO:0090322)2.47470348
169platelet dense granule organization (GO:0060155)2.46571111
170regulation of leukocyte degranulation (GO:0043300)2.44370146
171response to host immune response (GO:0052572)2.43378323
172response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.43378323
173mitochondrial calcium ion transport (GO:0006851)11.3628703

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.40716148
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.39391604
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.35959115
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.30047431
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.21373611
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.03565025
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.97934463
8ELF1_17652178_ChIP-ChIP_JURKAT_Human2.88438427
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.78327482
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.75921757
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.68490299
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.61501846
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.59862756
14RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.43803835
15IRF8_21731497_ChIP-ChIP_J774_Mouse2.43336071
16BP1_19119308_ChIP-ChIP_Hs578T_Human2.32507739
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.24753724
18MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.14642688
19STAT1_20625510_ChIP-Seq_HELA_Human2.09913732
20IRF8_22096565_ChIP-ChIP_GC-B_Human2.09795981
21PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.05822947
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.01945395
23YY1_21170310_ChIP-Seq_MESCs_Mouse1.97095000
24MYC_19079543_ChIP-ChIP_MESCs_Mouse1.96414516
25PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.89172188
26RARG_19884340_ChIP-ChIP_MEFs_Mouse1.88445059
27E2F1_18555785_ChIP-Seq_MESCs_Mouse1.87350889
28MYC_19030024_ChIP-ChIP_MESCs_Mouse1.86897751
29TFEB_21752829_ChIP-Seq_HELA_Human1.80363682
30CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.79010221
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.76949099
32LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.76779837
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.72006655
34XRN2_22483619_ChIP-Seq_HELA_Human1.71255956
35HOXB4_20404135_ChIP-ChIP_EML_Mouse1.67531789
36STAT3_1855785_ChIP-Seq_MESCs_Mouse1.62447322
37SCL_19346495_ChIP-Seq_HPC-7_Human1.62381698
38NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.57016703
39HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.55718486
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.55600416
41MYB_21317192_ChIP-Seq_ERMYB_Mouse1.55078066
42SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.54996800
43IKZF1_21737484_ChIP-ChIP_HCT116_Human1.53919432
44NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.52534207
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.51272295
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.50450666
47SRF_21415370_ChIP-Seq_HL-1_Mouse1.50262062
48POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.49506478
49VDR_24763502_ChIP-Seq_THP-1_Human1.48253459
50YY1_22570637_ChIP-Seq_MALME-3M_Human1.45740766
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.45526993
52STAT4_19710469_ChIP-ChIP_TH1__Mouse1.45141860
53DCP1A_22483619_ChIP-Seq_HELA_Human1.44687851
54ELK1_22589737_ChIP-Seq_MCF10A_Human1.43594756
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.42931792
56ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.42126451
57CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.41578096
58CTCF_18555785_ChIP-Seq_MESCs_Mouse1.39542483
59BCL6_27268052_Chip-Seq_Bcells_Human1.38794917
60CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.38079651
61ELK3_25401928_ChIP-Seq_HUVEC_Human1.37753521
62SPI1_23127762_ChIP-Seq_K562_Human1.37338499
63HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.37231569
64BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.36745911
65SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.35150160
66GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.34979440
67SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.34582795
68ELF1_20517297_ChIP-Seq_JURKAT_Human1.34497534
69TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.33821689
70LXR_22292898_ChIP-Seq_THP-1_Human1.31842153
71OCT4_18692474_ChIP-Seq_MEFs_Mouse1.31073631
72PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.30371607
73TP63_17297297_ChIP-ChIP_HaCaT_Human1.29793068
74NELFA_20434984_ChIP-Seq_ESCs_Mouse1.29777854
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.29493663
76SRY_22984422_ChIP-ChIP_TESTIS_Rat1.29467555
77SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.28790328
78CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.28784006
79VDR_23849224_ChIP-Seq_CD4+_Human1.28250842
80CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.26479306
81ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25981780
82VDR_21846776_ChIP-Seq_THP-1_Human1.24576931
83TET1_21451524_ChIP-Seq_MESCs_Mouse1.24002846
84NANOG_18555785_ChIP-Seq_MESCs_Mouse1.22596056
85BRD4_27068464_Chip-Seq_AML-cells_Mouse1.21160465
86GABP_19822575_ChIP-Seq_HepG2_Human1.20912617
87GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20488090
88TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.19432249
89SOX2_18692474_ChIP-Seq_MEFs_Mouse1.19063171
90SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.18202422
91BCOR_27268052_Chip-Seq_Bcells_Human1.16404085
92NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.14515512
93RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.13840445
94EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.13817936
95PU.1_20513432_ChIP-Seq_Bcells_Mouse1.13401639
96UTX_26944678_Chip-Seq_JUKART_Human1.13165856
97KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.12427626
98KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.12427626
99KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.12427626
100GATA1_19941827_ChIP-Seq_MEL_Mouse1.11694714
101KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11075234
102ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.10866205
103FOXP3_21729870_ChIP-Seq_TREG_Human1.10217923
104RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.10152290
105CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09861319
106CIITA_25753668_ChIP-Seq_RAJI_Human1.09136555
107SPI1_20517297_ChIP-Seq_HL60_Human1.08590835
108IRF8_27001747_Chip-Seq_BMDM_Mouse1.07331277
109CSB_26484114_Chip-Seq_FIBROBLAST_Human1.07019521
110TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06355248
111FOXP1_21924763_ChIP-Seq_HESCs_Human1.06338817
112MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.06105268
113E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.05405463
114SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05196594
115POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.04872826
116CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04658363
117ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.04233955
118TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04134162
119FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04090851
120ZNF263_19887448_ChIP-Seq_K562_Human1.03890352
121CTCF_26484167_Chip-Seq_Bcells_Mouse1.02643575
122SPI1_23547873_ChIP-Seq_NB4_Human1.01881675
123TP53_22127205_ChIP-Seq_IMR90_Human1.01092703
124P68_20966046_ChIP-Seq_HELA_Human0.98768054
125CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97930487
126GATA1_22383799_ChIP-Seq_G1ME_Mouse0.97256032
127ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.96592671
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95682129
129CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94537100
130PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94528497
131E2F1_20622854_ChIP-Seq_HELA_Human0.94485451
132TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94397063
133DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.93885299
134NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.92936051
135RAD21_21589869_ChIP-Seq_MESCs_Mouse0.92510286

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000013_abnormal_adipose_tissue8.26928509
2MP0005464_abnormal_platelet_physiology5.52036905
3MP0002938_white_spotting5.02963982
4MP0003878_abnormal_ear_physiology4.33617609
5MP0005377_hearing/vestibular/ear_phenot4.33617609
6MP0002102_abnormal_ear_morphology4.29194038
7MP0010307_abnormal_tumor_latency3.71908882
8MP0003786_premature_aging3.11694298
9MP0000003_abnormal_adipose_tissue3.09406998
10MP0000749_muscle_degeneration2.85520607
11MP0008004_abnormal_stomach_pH2.42188365
12MP0001835_abnormal_antigen_presentation2.40575628
13MP0000465_gastrointestinal_hemorrhage2.34033555
14MP0002148_abnormal_hypersensitivity_rea2.29275545
15MP0005058_abnormal_lysosome_morphology2.23004676
16MP0002837_dystrophic_cardiac_calcinosis2.12328977
17MP0003646_muscle_fatigue2.11904975
18MP0003075_altered_response_to2.11845690
19MP0009840_abnormal_foam_cell2.00469482
20MP0002132_abnormal_respiratory_system1.94964686
21MP0003879_abnormal_hair_cell1.85392107
22MP0005671_abnormal_response_to1.82169624
23MP0005397_hematopoietic_system_phenotyp1.81444602
24MP0001545_abnormal_hematopoietic_system1.81444602
25MP0005075_abnormal_melanosome_morpholog1.77617289
26MP0008438_abnormal_cutaneous_collagen1.77338471
27MP0003436_decreased_susceptibility_to1.76234834
28MP0005332_abnormal_amino_acid1.75574578
29MP0003186_abnormal_redox_activity1.74213140
30MP0005257_abnormal_intraocular_pressure1.74053802
31MP0006082_CNS_inflammation1.64453848
32MP0005083_abnormal_biliary_tract1.63770389
33MP0004510_myositis1.63583024
34MP0003724_increased_susceptibility_to1.60163512
35MP0003303_peritoneal_inflammation1.59037849
36MP0000685_abnormal_immune_system1.56451626
37MP0005165_increased_susceptibility_to1.55360279
38MP0000015_abnormal_ear_pigmentation1.52649426
39MP0005375_adipose_tissue_phenotype1.50784529
40MP0003950_abnormal_plasma_membrane1.49230301
41MP0009333_abnormal_splenocyte_physiolog1.48296124
42MP0008058_abnormal_DNA_repair1.45803343
43MP0001845_abnormal_inflammatory_respons1.44054993
44MP0004742_abnormal_vestibular_system1.42711286
45MP0005451_abnormal_body_composition1.41541376
46MP0006036_abnormal_mitochondrial_physio1.38168447
47MP0000751_myopathy1.37844145
48MP0000343_altered_response_to1.37334516
49MP0010155_abnormal_intestine_physiology1.37075931
50MP0009278_abnormal_bone_marrow1.35703692
51MP0001485_abnormal_pinna_reflex1.34099731
52MP0002398_abnormal_bone_marrow1.32452705
53MP0009764_decreased_sensitivity_to1.30903508
54MP0006035_abnormal_mitochondrial_morpho1.30163058
55MP0003866_abnormal_defecation1.27815653
56MP0009785_altered_susceptibility_to1.25052683
57MP0002429_abnormal_blood_cell1.21587858
58MP0005501_abnormal_skin_physiology1.19970064
59MP0005508_abnormal_skeleton_morphology1.17312358
60MP0003806_abnormal_nucleotide_metabolis1.16390749
61MP0000716_abnormal_immune_system1.15850021
62MP0005390_skeleton_phenotype1.14447344
63MP0002419_abnormal_innate_immunity1.14403238
64MP0005000_abnormal_immune_tolerance1.14386611
65MP0002722_abnormal_immune_system1.10399507
66MP0000490_abnormal_crypts_of1.07049652
67MP0009763_increased_sensitivity_to1.05964580
68MP0001533_abnormal_skeleton_physiology1.05872501
69MP0001542_abnormal_bone_strength1.04621107
70MP0005025_abnormal_response_to1.04248429
71MP0003656_abnormal_erythrocyte_physiolo0.98706497
72MP0000750_abnormal_muscle_regeneration0.98395106
73MP0001663_abnormal_digestive_system0.98085044
74MP0003638_abnormal_response/metabolism_0.96963883
75MP0003136_yellow_coat_color0.96902245
76MP0000858_altered_metastatic_potential0.96847567
77MP0005166_decreased_susceptibility_to0.96691722
78MP0004084_abnormal_cardiac_muscle0.96148198
79MP0003828_pulmonary_edema0.95848642
80MP0005319_abnormal_enzyme/_coenzyme0.95218366
81MP0004947_skin_inflammation0.94723271
82MP0005584_abnormal_enzyme/coenzyme_acti0.92668199
83MP0003300_gastrointestinal_ulcer0.89816454
84MP0001851_eye_inflammation0.89555013
85MP0000747_muscle_weakness0.88163894
86MP0002452_abnormal_antigen_presenting0.88091235
87MP0002405_respiratory_system_inflammati0.86833948
88MP0002254_reproductive_system_inflammat0.85036527
89MP0004036_abnormal_muscle_relaxation0.84605451
90MP0002998_abnormal_bone_remodeling0.84415380
91MP0006054_spinal_hemorrhage0.83179403
92MP0008874_decreased_physiological_sensi0.81991554
93MP0005410_abnormal_fertilization0.81903843
94MP0005408_hypopigmentation0.81812274
95MP0008873_increased_physiological_sensi0.80809306
96MP0003011_delayed_dark_adaptation0.80390080
97MP0003195_calcinosis0.79490325
98MP0008932_abnormal_embryonic_tissue0.78415833
99MP0009765_abnormal_xenobiotic_induced0.76846727
100MP0003693_abnormal_embryo_hatching0.75813041
101MP0010386_abnormal_urinary_bladder0.74974256
102MP0002723_abnormal_immune_serum0.74697571
103MP0002877_abnormal_melanocyte_morpholog0.74196699
104MP0004145_abnormal_muscle_electrophysio0.73815335
105MP0000920_abnormal_myelination0.73332690
106MP0004134_abnormal_chest_morphology0.72153193
107MP0000249_abnormal_blood_vessel0.70741718
108MP0000604_amyloidosis0.70366122
109MP0005365_abnormal_bile_salt0.70356116
110MP0004215_abnormal_myocardial_fiber0.70301068
111MP0009642_abnormal_blood_homeostasis0.68405928
112MP0002736_abnormal_nociception_after0.68378701
113MP0003795_abnormal_bone_structure0.68184166
114MP0001790_abnormal_immune_system0.67701610
115MP0005387_immune_system_phenotype0.67701610
116MP0005174_abnormal_tail_pigmentation0.67463746
117MP0001853_heart_inflammation0.67337495
118MP0003763_abnormal_thymus_physiology0.66489932
119MP0000681_abnormal_thyroid_gland0.66037497
120MP0005636_abnormal_mineral_homeostasis0.65985833
121MP0001958_emphysema0.65950695
122MP0002282_abnormal_trachea_morphology0.65462480
123MP0009643_abnormal_urine_homeostasis0.64053376
124MP0008469_abnormal_protein_level0.63801834
125MP0005330_cardiomyopathy0.63700124
126MP0005381_digestive/alimentary_phenotyp0.63432925
127MP0001819_abnormal_immune_cell0.63412955
128MP0003566_abnormal_cell_adhesion0.63307049
129MP0002277_abnormal_respiratory_mucosa0.63186844
130MP0002972_abnormal_cardiac_muscle0.62810824
131MP0002933_joint_inflammation0.62504804
132MP0005193_abnormal_anterior_eye0.62441874
133MP0002420_abnormal_adaptive_immunity0.61436805
134MP0009379_abnormal_foot_pigmentation0.61045406
135MP0003191_abnormal_cellular_cholesterol0.60971872
136MP0001879_abnormal_lymphatic_vessel0.60464760
137MP0001727_abnormal_embryo_implantation0.60456038
138MP0003172_abnormal_lysosome_physiology0.60150417
139MP0000372_irregular_coat_pigmentation0.59367034
140MP0002295_abnormal_pulmonary_circulatio0.59056990
141MP0000358_abnormal_cell_content/0.58392736
142MP0001800_abnormal_humoral_immune0.58373180
143MP0003718_maternal_effect0.57471159
144MP0008260_abnormal_autophagy0.56054685
145MP0003448_altered_tumor_morphology0.55847561
146MP0002019_abnormal_tumor_incidence0.55283998
147MP0000759_abnormal_skeletal_muscle0.53818175
148MP0005670_abnormal_white_adipose0.52063751
149MP0003279_aneurysm0.51484924
150MP0000689_abnormal_spleen_morphology0.50643854
151MP0005084_abnormal_gallbladder_morpholo0.50010156
152MP0003329_amyloid_beta_deposits0.49971605
153MP0002638_abnormal_pupillary_reflex0.49757162
154MP0001905_abnormal_dopamine_level0.49255307

Predicted human phenotypes

RankGene SetZ-score
1Congenital nonbullous ichthyosiform erythroderma (HP:0007479)9.12898092
2Entropion (HP:0000621)8.97885277
3Poikiloderma (HP:0001029)7.36760933
4Decreased subcutaneous fat (HP:0001002)7.17287535
5Petechiae (HP:0000967)6.84723514
6Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)6.69907736
7Fragile nails (HP:0001808)6.15179491
8Congenital ichthyosiform erythroderma (HP:0007431)5.94340421
9Abnormality of DNA repair (HP:0003254)5.69304063
10Prolonged bleeding time (HP:0003010)5.55992466
11Purpura (HP:0000979)5.47889283
12Prominent metopic ridge (HP:0005487)5.21242214
13Abnormality of subcutaneous fat tissue (HP:0001001)5.17636761
14Erythroderma (HP:0001019)5.15104749
15Generalized aminoaciduria (HP:0002909)4.63576383
16Renal Fanconi syndrome (HP:0001994)4.59279760
17Abnormality of the metopic suture (HP:0005556)4.38918060
18Menorrhagia (HP:0000132)4.27824456
19Abnormal platelet volume (HP:0011876)4.21686443
20Increased mean platelet volume (HP:0011877)4.15473097
21Epistaxis (HP:0000421)4.08880647
22Conjunctival hamartoma (HP:0100780)3.85752881
23Brittle hair (HP:0002299)3.75971261
24Decreased activity of mitochondrial respiratory chain (HP:0008972)3.41056646
25Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.41056646
26Death in childhood (HP:0003819)3.41007203
27Gingival bleeding (HP:0000225)3.40223252
28Male infertility (HP:0003251)3.37097551
29Abnormal platelet function (HP:0011869)3.17015445
30Impaired platelet aggregation (HP:0003540)3.17015445
31Cone-rod dystrophy (HP:0000548)3.13916268
32Vacuolated lymphocytes (HP:0001922)3.10750011
33Obstructive lung disease (HP:0006536)3.05885591
34Chronic obstructive pulmonary disease (HP:0006510)3.05885591
35Ectropion (HP:0000656)3.01291465
36Progressive macrocephaly (HP:0004481)2.92065787
37Abnormality of the costochondral junction (HP:0000919)2.90790329
38Abnormality of renal resorption (HP:0011038)2.82645543
39Abnormality of the heme biosynthetic pathway (HP:0010472)2.78084804
40Dysostosis multiplex (HP:0000943)2.76802344
41Recurrent corneal erosions (HP:0000495)2.75879956
42Hypophosphatemic rickets (HP:0004912)2.75305507
43Abnormal pupillary function (HP:0007686)2.72154410
44Stomatitis (HP:0010280)2.69368359
45IgG deficiency (HP:0004315)2.64379716
46Aplasia/Hypoplasia of the sacrum (HP:0008517)2.61815805
47Increased serum ferritin (HP:0003281)2.60240444
48Abnormality of fatty-acid metabolism (HP:0004359)2.55677012
49Acute necrotizing encephalopathy (HP:0006965)2.47649496
50Abnormality of iron homeostasis (HP:0011031)2.45927622
51Mitochondrial inheritance (HP:0001427)2.45828434
52Bone cyst (HP:0012062)2.45811844
53Abnormality of cells of the erythroid lineage (HP:0012130)2.42351549
54Progressive neurologic deterioration (HP:0002344)2.39451065
55Keratitis (HP:0000491)2.38837740
56Increased IgM level (HP:0003496)2.38019979
57Hepatocellular necrosis (HP:0001404)2.37688251
58Hepatic necrosis (HP:0002605)2.37202601
59Failure to thrive in infancy (HP:0001531)2.35084811
60Stomach cancer (HP:0012126)2.33229450
61Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.28991707
62Abnormality of macrophages (HP:0004311)2.23826073
63Abnormal number of erythroid precursors (HP:0012131)2.22199988
64Type I transferrin isoform profile (HP:0003642)2.21334479
65Recurrent abscess formation (HP:0002722)2.20824274
66Aplastic anemia (HP:0001915)2.19880329
673-Methylglutaconic aciduria (HP:0003535)2.19848643
68Hypertensive crisis (HP:0100735)2.19824453
69Abnormal mitochondria in muscle tissue (HP:0008316)2.18390423
70Abnormality of urine glucose concentration (HP:0011016)2.18173661
71Glycosuria (HP:0003076)2.18173661
72Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.16785994
73Abnormality of lateral ventricle (HP:0030047)2.16096100
74Lactic acidosis (HP:0003128)2.16039018
75Cerebral edema (HP:0002181)2.15898862
76Acute encephalopathy (HP:0006846)2.15076412
77Episodic fever (HP:0001954)2.14328763
78Increased hepatocellular lipid droplets (HP:0006565)2.12804271
79Loss of speech (HP:0002371)2.12533057
80Increased CSF lactate (HP:0002490)2.10131948
81Axonal loss (HP:0003447)2.09016269
82Multiple lipomas (HP:0001012)2.08970954
83Lipid accumulation in hepatocytes (HP:0006561)2.07395216
84Neonatal respiratory distress (HP:0002643)2.06722635
85Abnormality of glycolipid metabolism (HP:0010969)2.04774869
86Abnormality of liposaccharide metabolism (HP:0010968)2.04774869
87Abnormality of glycosphingolipid metabolism (HP:0004343)2.04774869
88Paralysis (HP:0003470)2.04215929
89Distal lower limb muscle weakness (HP:0009053)2.04104800
90Exertional dyspnea (HP:0002875)2.02442210
91Choreoathetosis (HP:0001266)2.02200176
92Spontaneous hematomas (HP:0007420)2.01194208
93Abnormality of transition element cation homeostasis (HP:0011030)2.01087587
94Muscle fibrillation (HP:0010546)1.98849034
95Tongue fasciculations (HP:0001308)1.95820257
96Increased cerebral lipofuscin (HP:0011813)1.95598076
97Hyperlipoproteinemia (HP:0010980)1.94690859
98Hyperthyroidism (HP:0000836)1.94542224
99Megalencephaly (HP:0001355)1.93903144
100Albinism (HP:0001022)1.93634430
101Increased neuronal autofluorescent lipopigment (HP:0002074)1.91519430
102Abnormality of aromatic amino acid family metabolism (HP:0004338)1.90438258
103Amyloidosis (HP:0011034)1.90293987
104Cholecystitis (HP:0001082)1.89671413
105Abnormal gallbladder physiology (HP:0012438)1.89671413
106Angiofibromas (HP:0010615)1.88554716
107Adenoma sebaceum (HP:0009720)1.88554716
108Abnormal protein glycosylation (HP:0012346)1.87718676
109Abnormal glycosylation (HP:0012345)1.87718676
110Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.87718676
111Abnormal protein N-linked glycosylation (HP:0012347)1.87718676
112Dicarboxylic aciduria (HP:0003215)1.87302809
113Abnormality of dicarboxylic acid metabolism (HP:0010995)1.87302809
114Premature rupture of membranes (HP:0001788)1.86993868
115Mucosal telangiectasiae (HP:0100579)1.86829395
116Urticaria (HP:0001025)1.85417863
117Spastic paraparesis (HP:0002313)1.84728327
118Myositis (HP:0100614)1.83868772
119Cerebral hypomyelination (HP:0006808)1.83857547
120Hypokinesia (HP:0002375)1.83051182
121Abnormality of the vasculature of the conjunctiva (HP:0008054)1.82751734
122Recurrent bacterial skin infections (HP:0005406)1.82478954
123Muscle fiber splitting (HP:0003555)1.81157943
124Ventricular tachycardia (HP:0004756)1.80952892
125Increased serum lactate (HP:0002151)1.80167939
126Ragged-red muscle fibers (HP:0003200)1.80166760
127Increased muscle lipid content (HP:0009058)1.78955046
128Thrombocytosis (HP:0001894)1.78806895
129Systemic lupus erythematosus (HP:0002725)1.78804092
130Vertebral compression fractures (HP:0002953)1.77970262
131Respiratory failure (HP:0002878)1.77341273
132Recurrent fungal infections (HP:0002841)1.77140223
133Cutaneous photosensitivity (HP:0000992)1.76470457
134Opisthotonus (HP:0002179)1.75317497
135Bruising susceptibility (HP:0000978)1.74741603
136Poor head control (HP:0002421)1.74471133
137Increased intramyocellular lipid droplets (HP:0012240)1.74185613
138Cerebral palsy (HP:0100021)1.73765937
139Hamartoma of the eye (HP:0010568)1.73199081
140Nausea (HP:0002018)1.72887556
141Progressive visual loss (HP:0000529)1.71985721
142Abnormality of the anterior horn cell (HP:0006802)1.70493647
143Cavernous hemangioma (HP:0001048)1.65557876
144Maternal diabetes (HP:0009800)1.65022131
145Prolonged neonatal jaundice (HP:0006579)1.61331875
146Testicular atrophy (HP:0000029)1.60624976
147Hepatosplenomegaly (HP:0001433)1.60586498
148Exercise intolerance (HP:0003546)1.60515136
149Eczematoid dermatitis (HP:0000976)1.58716592
150Rough bone trabeculation (HP:0100670)1.56232613
151Abnormal drinking behavior (HP:0030082)1.55938987
152Polydipsia (HP:0001959)1.55938987
153Mesangial abnormality (HP:0001966)1.55886131
154Elevated erythrocyte sedimentation rate (HP:0003565)1.54642597
155Rocker bottom foot (HP:0001838)1.53252981
156Arthrogryposis multiplex congenita (HP:0002804)1.52368444
157Deep palmar crease (HP:0006191)1.52300718
158Abnormality of the septum pellucidum (HP:0007375)1.52224198
159Recurrent gram-negative bacterial infections (HP:0005420)1.52224182

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK25.68995420
2BUB15.19402810
3NME24.43103430
4BRAF4.13353149
5VRK24.03759063
6PINK13.84519195
7PIM22.85719969
8MAP2K22.74461526
9TAOK12.60541263
10STK162.31998232
11LIMK12.27892795
12MST42.07058286
13TESK22.06485986
14BLK1.85450233
15IRAK31.80695919
16MAP3K31.80486953
17GRK61.74959875
18TAOK21.66536756
19BMX1.63428702
20MAP3K81.63321103
21IRAK41.62237507
22ABL21.60207979
23ARAF1.53431993
24EPHB11.53144858
25MAP3K121.50993561
26CSF1R1.43422651
27ILK1.36492650
28BCKDK1.35086894
29TESK11.34034323
30SIK31.33346932
31BTK1.31497880
32MAPKAPK31.21041754
33DAPK11.19950995
34BMPR1B1.18159451
35ERN11.15842183
36TLK11.13676153
37KDR1.13613940
38CLK11.11939503
39FGR1.11490781
40MYLK1.10503233
41TTN1.09438086
42WEE11.08957845
43PTK2B1.06829790
44TEC1.06591431
45LMTK21.06533443
46TBK11.05016914
47NME11.04421124
48DMPK1.04125697
49DYRK21.02910929
50CDK191.00755909
51DAPK30.99175214
52SCYL20.97729834
53INSRR0.94579190
54PBK0.91682414
55MAP4K10.90350896
56VRK10.88927421
57PAK40.84913928
58TRIB30.81528876
59STK40.81263011
60DYRK30.76794435
61KIT0.76039487
62ZAP700.75657404
63HCK0.75554116
64EIF2AK10.74592127
65PDK30.74494040
66PDK40.74494040
67AURKA0.74416594
68FES0.74127781
69GRK70.74051749
70JAK30.72937846
71LRRK20.72928260
72WNK40.71866281
73FLT30.71714564
74PHKG20.70571185
75PHKG10.70571185
76PKN20.68249662
77MAP3K10.68087008
78PAK10.67982191
79EPHA20.67457169
80OBSCN0.65834689
81IKBKB0.63871803
82TXK0.63505377
83BMPR20.63445846
84SMG10.62957180
85ADRBK20.62604911
86PRKD20.61196030
87PRKG20.60234067
88PDK20.59988111
89RIPK40.59050482
90PLK40.58027846
91MAP4K20.57918674
92PRKD10.55050598
93LYN0.54359868
94TGFBR10.54109236
95STK100.53599116
96IRAK10.52576476
97CDK80.51283537
98CAMK2D0.50819235
99MAP3K50.48651627
100NUAK10.48234320
101RPS6KA40.46352035
102IKBKE0.45835396
103CSNK1G30.45484923
104TYK20.45082850
105SYK0.44239265
106MKNK20.44184709
107PIK3CG0.43596445
108CDK140.43482313
109PDPK10.43181785
110SIK10.42773218
111ADRBK10.42267285
112MAP2K60.41605620
113CAMK2G0.39509170
114NEK90.39202890
115TGFBR20.38897903
116PRKCD0.38341646
117CSK0.38290692
118MARK30.36596408
119CDK70.36557307
120GRK50.34838448
121PRKCI0.34497623
122NEK10.34442099
123ROCK20.32735733
124MAPKAPK20.31456542
125CASK0.31204679
126NTRK10.30918074
127EIF2AK30.30878134
128TRIM280.30149844
129TRPM70.29718184
130LCK0.28897513
131MAP3K110.28750733
132PRKCE0.27991372
133MAP2K30.27119706
134MET0.25936260
135CSNK2A10.25330322
136TNK20.24824937
137MATK0.24695187
138MKNK10.23523859

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA polymerase_Homo sapiens_hsa030204.41038782
2Ribosome_Homo sapiens_hsa030103.90798304
3Proteasome_Homo sapiens_hsa030503.89742466
4Nucleotide excision repair_Homo sapiens_hsa034203.71735377
5Oxidative phosphorylation_Homo sapiens_hsa001903.67672707
6Parkinsons disease_Homo sapiens_hsa050122.95576341
7DNA replication_Homo sapiens_hsa030302.71354254
8SNARE interactions in vesicular transport_Homo sapiens_hsa041302.65595589
9Mismatch repair_Homo sapiens_hsa034302.62405419
10Basal transcription factors_Homo sapiens_hsa030222.49334312
11Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.41012839
12Huntingtons disease_Homo sapiens_hsa050162.26497522
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.14274594
14Protein export_Homo sapiens_hsa030602.01120471
15Pyrimidine metabolism_Homo sapiens_hsa002401.98342054
16Alzheimers disease_Homo sapiens_hsa050101.97890436
17Sulfur metabolism_Homo sapiens_hsa009201.94793111
18Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.90960564
19Lysosome_Homo sapiens_hsa041421.88550258
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.84356216
21Homologous recombination_Homo sapiens_hsa034401.63608992
22Platelet activation_Homo sapiens_hsa046111.63218446
23Other glycan degradation_Homo sapiens_hsa005111.55083574
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.53089033
25Vitamin B6 metabolism_Homo sapiens_hsa007501.49255592
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.47290887
27Hematopoietic cell lineage_Homo sapiens_hsa046401.46183490
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45415998
29Autoimmune thyroid disease_Homo sapiens_hsa053201.41334721
30Galactose metabolism_Homo sapiens_hsa000521.33277083
31Cardiac muscle contraction_Homo sapiens_hsa042601.26715775
32Type I diabetes mellitus_Homo sapiens_hsa049401.23498328
33Rheumatoid arthritis_Homo sapiens_hsa053231.15882955
34Fructose and mannose metabolism_Homo sapiens_hsa000511.15674986
35Phagosome_Homo sapiens_hsa041451.13329111
36Prion diseases_Homo sapiens_hsa050201.12258545
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.09742247
38Primary immunodeficiency_Homo sapiens_hsa053401.05685364
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.03446382
40Glutathione metabolism_Homo sapiens_hsa004801.01899008
41Collecting duct acid secretion_Homo sapiens_hsa049661.01333523
42Folate biosynthesis_Homo sapiens_hsa007900.98264767
43Purine metabolism_Homo sapiens_hsa002300.95976660
44Base excision repair_Homo sapiens_hsa034100.94046210
45Intestinal immune network for IgA production_Homo sapiens_hsa046720.92222769
46Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.91876341
47Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.91061593
48Carbon metabolism_Homo sapiens_hsa012000.88844674
49Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.87685512
50Pertussis_Homo sapiens_hsa051330.85748295
51Vibrio cholerae infection_Homo sapiens_hsa051100.84495995
52Fatty acid elongation_Homo sapiens_hsa000620.82028160
53N-Glycan biosynthesis_Homo sapiens_hsa005100.81512634
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.79936198
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79828253
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.79435459
57Staphylococcus aureus infection_Homo sapiens_hsa051500.77387465
58Arachidonic acid metabolism_Homo sapiens_hsa005900.76876328
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74458895
60Steroid biosynthesis_Homo sapiens_hsa001000.73764692
61Arginine and proline metabolism_Homo sapiens_hsa003300.73753953
62Glycosaminoglycan degradation_Homo sapiens_hsa005310.69037063
63Endocytosis_Homo sapiens_hsa041440.68651695
64Leishmaniasis_Homo sapiens_hsa051400.66641294
65Pentose phosphate pathway_Homo sapiens_hsa000300.66125944
66Epstein-Barr virus infection_Homo sapiens_hsa051690.65617339
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.64595950
68Renal cell carcinoma_Homo sapiens_hsa052110.63406930
69HIF-1 signaling pathway_Homo sapiens_hsa040660.61439717
70Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60263077
71Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60094249
72Peroxisome_Homo sapiens_hsa041460.59616568
73Metabolic pathways_Homo sapiens_hsa011000.59236693
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58406432
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.56583743
76Malaria_Homo sapiens_hsa051440.55644734
77Biosynthesis of amino acids_Homo sapiens_hsa012300.54382466
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.54027853
79Melanoma_Homo sapiens_hsa052180.52207113
80Legionellosis_Homo sapiens_hsa051340.50057356
81Toxoplasmosis_Homo sapiens_hsa051450.49284619
82Graft-versus-host disease_Homo sapiens_hsa053320.48669235
83Herpes simplex infection_Homo sapiens_hsa051680.48643120
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.47891973
85Acute myeloid leukemia_Homo sapiens_hsa052210.45847759
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.45801597
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.44348389
88Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42783588
89Asthma_Homo sapiens_hsa053100.40837896
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40518836
91Shigellosis_Homo sapiens_hsa051310.40267526
92Spliceosome_Homo sapiens_hsa030400.39530825
93Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39472541
94Apoptosis_Homo sapiens_hsa042100.39433671
95VEGF signaling pathway_Homo sapiens_hsa043700.39393933
96Chemokine signaling pathway_Homo sapiens_hsa040620.39055188
97Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.38533711
98Thyroid cancer_Homo sapiens_hsa052160.38146424
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.37757156
100Synaptic vesicle cycle_Homo sapiens_hsa047210.36101927
101Influenza A_Homo sapiens_hsa051640.35967128
102RNA transport_Homo sapiens_hsa030130.35732405
103Bladder cancer_Homo sapiens_hsa052190.34639052
104Viral myocarditis_Homo sapiens_hsa054160.34498855
105Sulfur relay system_Homo sapiens_hsa041220.34317609
106beta-Alanine metabolism_Homo sapiens_hsa004100.34299352
107Tuberculosis_Homo sapiens_hsa051520.33484757
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.32639038
109Antigen processing and presentation_Homo sapiens_hsa046120.32356512
110Central carbon metabolism in cancer_Homo sapiens_hsa052300.31550396
111Primary bile acid biosynthesis_Homo sapiens_hsa001200.31210424
112Allograft rejection_Homo sapiens_hsa053300.30975218
113Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29939989
114Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.29016172
115Salmonella infection_Homo sapiens_hsa051320.28551118
116One carbon pool by folate_Homo sapiens_hsa006700.28452984
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27998831
118Sphingolipid metabolism_Homo sapiens_hsa006000.27560566
119Osteoclast differentiation_Homo sapiens_hsa043800.27231715
120Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.27100035
121Linoleic acid metabolism_Homo sapiens_hsa005910.25005359
122Pyruvate metabolism_Homo sapiens_hsa006200.24619664
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.24298325
124Regulation of autophagy_Homo sapiens_hsa041400.21702306
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.21035606
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.20429750
127Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.19811777
128B cell receptor signaling pathway_Homo sapiens_hsa046620.19276060
129Phenylalanine metabolism_Homo sapiens_hsa003600.17053999
130Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.16969559

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