LAMTOR4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.44598063
2ATP synthesis coupled proton transport (GO:0015986)5.38475699
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.38475699
4establishment of protein localization to mitochondrial membrane (GO:0090151)5.30857683
5mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.17013514
6respiratory electron transport chain (GO:0022904)4.75803011
7electron transport chain (GO:0022900)4.63223744
8viral transcription (GO:0019083)4.48644686
9ribosomal small subunit biogenesis (GO:0042274)4.44264187
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.25886635
11cotranslational protein targeting to membrane (GO:0006613)4.25315762
12ribosomal small subunit assembly (GO:0000028)4.25163162
13translational termination (GO:0006415)4.24713422
14protein targeting to ER (GO:0045047)4.20163022
15aldehyde catabolic process (GO:0046185)4.17974518
16protein localization to endoplasmic reticulum (GO:0070972)4.06943722
17establishment of protein localization to endoplasmic reticulum (GO:0072599)3.99135244
18deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.85882617
19erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.84294384
20L-phenylalanine catabolic process (GO:0006559)3.84294384
21negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.80129399
22erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.78196686
23L-phenylalanine metabolic process (GO:0006558)3.78196686
24translational elongation (GO:0006414)3.59156450
25protein complex biogenesis (GO:0070271)3.57609569
26DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.50906358
27mitochondrial respiratory chain complex I assembly (GO:0032981)3.49207531
28NADH dehydrogenase complex assembly (GO:0010257)3.49207531
29mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.49207531
30chaperone-mediated protein transport (GO:0072321)3.47653348
31response to interferon-beta (GO:0035456)3.46436833
32platelet dense granule organization (GO:0060155)3.46389598
33fatty acid elongation (GO:0030497)3.46308349
34negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.45108403
35negative regulation of ligase activity (GO:0051352)3.45108403
36positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.41020410
37GTP biosynthetic process (GO:0006183)3.40468480
38signal peptide processing (GO:0006465)3.37845202
39intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.36188418
40signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.36188418
41signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.35999595
42signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.35999595
43signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.35999595
44termination of RNA polymerase III transcription (GO:0006386)3.34779030
45transcription elongation from RNA polymerase III promoter (GO:0006385)3.34779030
46viral life cycle (GO:0019058)3.32467435
47oxidative phosphorylation (GO:0006119)3.28978161
48mitochondrial respiratory chain complex assembly (GO:0033108)3.27601689
49regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.27006270
50establishment of protein localization to mitochondrion (GO:0072655)3.26153837
51cellular protein complex disassembly (GO:0043624)3.21345231
52signal transduction involved in DNA damage checkpoint (GO:0072422)3.19479171
53signal transduction involved in DNA integrity checkpoint (GO:0072401)3.19479171
54pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.15118787
55respiratory chain complex IV assembly (GO:0008535)3.14160343
56signal transduction involved in cell cycle checkpoint (GO:0072395)3.12577904
57deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.12365543
58purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.12360745
59protein localization to mitochondrion (GO:0070585)3.10504333
60RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.09717833
61tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.09717833
62DNA deamination (GO:0045006)3.05262989
63glyoxylate metabolic process (GO:0046487)3.03770564
64neutrophil activation involved in immune response (GO:0002283)3.01339427
65cofactor catabolic process (GO:0051187)3.00279291
66immunoglobulin mediated immune response (GO:0016064)2.99241570
67aromatic amino acid family catabolic process (GO:0009074)2.99152968
68cytidine metabolic process (GO:0046087)2.98512554
69cytidine catabolic process (GO:0006216)2.98512554
70cytidine deamination (GO:0009972)2.98512554
71nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.96064912
72purine deoxyribonucleotide catabolic process (GO:0009155)2.96024499
73deoxyribonucleotide catabolic process (GO:0009264)2.94269481
74anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.93363237
75killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.92795234
76disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.92795234
77cytochrome complex assembly (GO:0017004)2.92505492
78rRNA modification (GO:0000154)2.91884890
79hydrogen ion transmembrane transport (GO:1902600)2.91794572
80antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.91361755
81guanosine-containing compound biosynthetic process (GO:1901070)2.91103074
82inner mitochondrial membrane organization (GO:0007007)2.89325486
83pseudouridine synthesis (GO:0001522)2.88928001
84regulation of mitochondrial translation (GO:0070129)2.88459129
85translation (GO:0006412)2.88179213
86positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.87116179
87respiratory burst (GO:0045730)2.86989689
88protein targeting to membrane (GO:0006612)2.86873910
89ATP biosynthetic process (GO:0006754)2.85762076
90cellular response to interferon-beta (GO:0035458)2.85727395
91positive regulation of cellular amine metabolic process (GO:0033240)2.84482786
92antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.84127860
93proteasome assembly (GO:0043248)2.84108254
94amyloid precursor protein catabolic process (GO:0042987)2.83477818
95deoxyribose phosphate catabolic process (GO:0046386)2.81992575
96nucleoside triphosphate biosynthetic process (GO:0009142)2.80955582
97UTP biosynthetic process (GO:0006228)2.79963714
98positive regulation of ligase activity (GO:0051351)2.77908417
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.77860093
100nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.77425655
101translational initiation (GO:0006413)2.77273437
102regulation of oxidative phosphorylation (GO:0002082)2.76796624
103purine nucleoside triphosphate biosynthetic process (GO:0009145)2.75823954
104sulfur amino acid catabolic process (GO:0000098)2.74963484
105protein neddylation (GO:0045116)2.74146486
106purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.73061780
107sequestering of actin monomers (GO:0042989)2.69488680
108cholesterol biosynthetic process (GO:0006695)2.68929467
109proton transport (GO:0015992)2.68520629
110coenzyme catabolic process (GO:0009109)2.67395360
111hydrogen transport (GO:0006818)2.65617081
112ribosomal large subunit biogenesis (GO:0042273)2.64158949
113glutathione metabolic process (GO:0006749)2.62981528
114pentose metabolic process (GO:0019321)2.60587969
115regulation of cellular amino acid metabolic process (GO:0006521)2.60153253
116maturation of SSU-rRNA (GO:0030490)2.59413892
117bile acid biosynthetic process (GO:0006699)2.58327702
118branched-chain amino acid catabolic process (GO:0009083)2.56876535
119lipoxygenase pathway (GO:0019372)2.56645946
120cellular ketone body metabolic process (GO:0046950)2.55991850
121L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.55079685
122reactive oxygen species biosynthetic process (GO:1903409)2.54761161
123protein complex disassembly (GO:0043241)2.53621727
124amino acid salvage (GO:0043102)2.52415794
125L-methionine salvage (GO:0071267)2.52415794
126L-methionine biosynthetic process (GO:0071265)2.52415794
127fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.49952373
128protein targeting to mitochondrion (GO:0006626)2.49158238
129very long-chain fatty acid metabolic process (GO:0000038)2.46096993
130glutathione biosynthetic process (GO:0006750)2.44968640
131sterol biosynthetic process (GO:0016126)2.44929946
132mitochondrial transport (GO:0006839)2.44756724
133fatty-acyl-CoA metabolic process (GO:0035337)2.44272545
134ethanol oxidation (GO:0006069)2.44092972
135glutathione derivative metabolic process (GO:1901685)2.44045340
136glutathione derivative biosynthetic process (GO:1901687)2.44045340
137ribonucleoside triphosphate biosynthetic process (GO:0009201)2.43729768
138hydrogen peroxide metabolic process (GO:0042743)2.42973623
139amyloid precursor protein metabolic process (GO:0042982)2.42470387
140fatty acid catabolic process (GO:0009062)2.42376644
141antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.41914004
142macromolecular complex disassembly (GO:0032984)2.41229825
143thioester metabolic process (GO:0035383)2.41066984
144acyl-CoA metabolic process (GO:0006637)2.41066984
145GDP-mannose metabolic process (GO:0019673)2.40131319
146hydrogen peroxide catabolic process (GO:0042744)2.39148190

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.66337220
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.36062589
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.67102439
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.50843573
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.27911576
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.18632425
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.98109489
8BP1_19119308_ChIP-ChIP_Hs578T_Human2.96746494
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.96107721
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.78594237
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.77808414
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.77150614
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.76853293
14RXR_22158963_ChIP-Seq_LIVER_Mouse2.71322220
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.68719519
16EGR1_23403033_ChIP-Seq_LIVER_Mouse2.62782578
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.53193705
18PPARA_22158963_ChIP-Seq_LIVER_Mouse2.44534593
19IRF8_22096565_ChIP-ChIP_GC-B_Human2.44016039
20PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.29432068
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.29277460
22CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.28795271
23SRF_21415370_ChIP-Seq_HL-1_Mouse2.20401951
24CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.13898641
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.08644315
26IRF8_21731497_ChIP-ChIP_J774_Mouse2.07795508
27HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.04418431
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.03824305
29FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.03174668
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.98924632
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.91596027
32MYC_18358816_ChIP-ChIP_MESCs_Mouse1.89712124
33NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.84674589
34MYC_18555785_ChIP-Seq_MESCs_Mouse1.84318039
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.83439403
36FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.80377116
37IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.76710732
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.65450503
39LXR_22158963_ChIP-Seq_LIVER_Mouse1.63529083
40HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.61671644
41SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.60010009
42DCP1A_22483619_ChIP-Seq_HELA_Human1.58413812
43LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.57521903
44VDR_23849224_ChIP-Seq_CD4+_Human1.53264754
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53214161
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.49877460
47MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.48724865
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.47697531
49STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.47004779
50YY1_21170310_ChIP-Seq_MESCs_Mouse1.41306401
51TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40560159
52ERG_20887958_ChIP-Seq_HPC-7_Mouse1.37994186
53SPI1_23547873_ChIP-Seq_NB4_Human1.35922725
54FOXP3_21729870_ChIP-Seq_TREG_Human1.31851892
55XRN2_22483619_ChIP-Seq_HELA_Human1.28537405
56MYB_21317192_ChIP-Seq_ERMYB_Mouse1.27905598
57THAP11_20581084_ChIP-Seq_MESCs_Mouse1.26631617
58MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.24503353
59ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24288542
60NELFA_20434984_ChIP-Seq_ESCs_Mouse1.20123453
61FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16634949
62CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15855614
63CTCF_18555785_ChIP-Seq_MESCs_Mouse1.15697908
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.15412170
65CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.14729660
66MYC_19030024_ChIP-ChIP_MESCs_Mouse1.14292323
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14164010
68ELF1_20517297_ChIP-Seq_JURKAT_Human1.14113652
69MYC_18940864_ChIP-ChIP_HL60_Human1.12931817
70PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12190354
71LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10266579
72CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09561812
73ELK1_19687146_ChIP-ChIP_HELA_Human1.08760886
74GABP_19822575_ChIP-Seq_HepG2_Human1.06877682
75FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.06332907
76STAT4_19710469_ChIP-ChIP_TH1__Mouse1.06123837
77ELK1_22589737_ChIP-Seq_MCF10A_Human1.04930763
78KDM5A_27292631_Chip-Seq_BREAST_Human1.04585072
79CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04576245
80CTCF_26484167_Chip-Seq_Bcells_Mouse1.04342610
81CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02283139
82PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01524601
83IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.01303729
84MAF_26560356_Chip-Seq_TH2_Human1.01129582
85CIITA_25753668_ChIP-Seq_RAJI_Human1.01125622
86GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00969971
87SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.00626345
88BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.00033694
89STAT1_20625510_ChIP-Seq_HELA_Human0.99972460
90SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.99617882
91EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99107274
92SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98895680
93ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.97968260
94FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.97911834
95GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.97791321
96SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97468672
97SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97353315
98BCOR_27268052_Chip-Seq_Bcells_Human0.96072286
99VDR_21846776_ChIP-Seq_THP-1_Human0.96011113
100FOXP1_21924763_ChIP-Seq_HESCs_Human0.95732375
101YY1_22570637_ChIP-Seq_MALME-3M_Human0.95523867
102CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94259345
103PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94012631
104RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93841047
105NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.93808068
106SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.92997973
107SCL_19346495_ChIP-Seq_HPC-7_Human0.92437646
108PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.92222037
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.91806659
110SA1_27219007_Chip-Seq_Bcells_Human0.90893484
111P300_27268052_Chip-Seq_Bcells_Human0.90765406
112SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90235346
113TTF2_22483619_ChIP-Seq_HELA_Human0.90162369
114IKZF1_21737484_ChIP-ChIP_HCT116_Human0.90061222
115TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89306339
116IRF8_27001747_Chip-Seq_BMDM_Mouse0.89195561
117NANOG_20526341_ChIP-Seq_ESCs_Human0.88290362
118NANOG_18555785_ChIP-Seq_MESCs_Mouse0.88169240
119CTCF_20526341_ChIP-Seq_ESCs_Human0.87638831
120BCL6_27268052_Chip-Seq_Bcells_Human0.87508884
121PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.87212168
122TAF2_19829295_ChIP-Seq_ESCs_Human0.87040009
123MYC_19079543_ChIP-ChIP_MESCs_Mouse0.86423777
124UTX_26944678_Chip-Seq_JUKART_Human0.85802404

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis4.08612389
2MP0002139_abnormal_hepatobiliary_system4.05613185
3MP0005360_urolithiasis3.37952613
4MP0008875_abnormal_xenobiotic_pharmacok3.08562429
5MP0003186_abnormal_redox_activity3.00951482
6MP0005085_abnormal_gallbladder_physiolo2.84430888
7MP0009379_abnormal_foot_pigmentation2.64350198
8MP0005365_abnormal_bile_salt2.62857915
9MP0002277_abnormal_respiratory_mucosa2.57647749
10MP0009840_abnormal_foam_cell2.55252320
11MP0003195_calcinosis2.55191343
12MP0005451_abnormal_body_composition2.42175208
13MP0003724_increased_susceptibility_to2.37848667
14MP0006036_abnormal_mitochondrial_physio2.31705283
15MP0009785_altered_susceptibility_to2.23172250
16MP0005058_abnormal_lysosome_morphology2.18092578
17MP0001835_abnormal_antigen_presentation2.15496306
18MP0003436_decreased_susceptibility_to2.14475729
19MP0002148_abnormal_hypersensitivity_rea2.13956644
20MP0005332_abnormal_amino_acid2.05808946
21MP0005083_abnormal_biliary_tract2.00569482
22MP0003191_abnormal_cellular_cholesterol1.93921215
23MP0005025_abnormal_response_to1.90456325
24MP0002419_abnormal_innate_immunity1.84362338
25MP0001764_abnormal_homeostasis1.81296428
26MP0003011_delayed_dark_adaptation1.74085964
27MP0005584_abnormal_enzyme/coenzyme_acti1.72468236
28MP0005000_abnormal_immune_tolerance1.67901731
29MP0010329_abnormal_lipoprotein_level1.63791176
30MP0001986_abnormal_taste_sensitivity1.59736471
31MP0001853_heart_inflammation1.58499385
32MP0004381_abnormal_hair_follicle1.56936393
33MP0001529_abnormal_vocalization1.55742861
34MP0008469_abnormal_protein_level1.53664593
35MP0005464_abnormal_platelet_physiology1.52068413
36MP0006082_CNS_inflammation1.51351802
37MP0009643_abnormal_urine_homeostasis1.49774526
38MP0003656_abnormal_erythrocyte_physiolo1.49647785
39MP0002837_dystrophic_cardiac_calcinosis1.49341313
40MP0005408_hypopigmentation1.48596364
41MP0002876_abnormal_thyroid_physiology1.47572579
42MP0005319_abnormal_enzyme/_coenzyme1.45133283
43MP0000920_abnormal_myelination1.44683463
44MP0001905_abnormal_dopamine_level1.44152611
45MP0002653_abnormal_ependyma_morphology1.44086866
46MP0005636_abnormal_mineral_homeostasis1.43173149
47MP0002118_abnormal_lipid_homeostasis1.40382082
48MP0005671_abnormal_response_to1.37881053
49MP0006072_abnormal_retinal_apoptosis1.33779601
50MP0001666_abnormal_nutrient_absorption1.32698921
51MP0005075_abnormal_melanosome_morpholog1.32336669
52MP0004019_abnormal_vitamin_homeostasis1.32098751
53MP0008058_abnormal_DNA_repair1.30282663
54MP0002723_abnormal_immune_serum1.28917221
55MP0000685_abnormal_immune_system1.26928363
56MP0006035_abnormal_mitochondrial_morpho1.24770143
57MP0003786_premature_aging1.23529820
58MP0001845_abnormal_inflammatory_respons1.21264435
59MP0003878_abnormal_ear_physiology1.19433733
60MP0005377_hearing/vestibular/ear_phenot1.19433733
61MP0000343_altered_response_to1.19071058
62MP0003866_abnormal_defecation1.17990389
63MP0003172_abnormal_lysosome_physiology1.17932110
64MP0006292_abnormal_olfactory_placode1.17880877
65MP0005174_abnormal_tail_pigmentation1.17694751
66MP0002398_abnormal_bone_marrow1.16611566
67MP0000372_irregular_coat_pigmentation1.16281180
68MP0000609_abnormal_liver_physiology1.16199966
69MP0004782_abnormal_surfactant_physiolog1.14647131
70MP0001800_abnormal_humoral_immune1.14281445
71MP0005387_immune_system_phenotype1.14131015
72MP0001790_abnormal_immune_system1.14131015
73MP0004142_abnormal_muscle_tone1.13692013
74MP0002420_abnormal_adaptive_immunity1.12596342
75MP0002163_abnormal_gland_morphology1.10738937
76MP0009764_decreased_sensitivity_to1.10668769
77MP0001819_abnormal_immune_cell1.10644951
78MP0002452_abnormal_antigen_presenting1.10548901
79MP0001533_abnormal_skeleton_physiology1.08869097
80MP0002132_abnormal_respiratory_system1.07450852
81MP0000604_amyloidosis1.01354572
82MP0002095_abnormal_skin_pigmentation1.01198576
83MP0003303_peritoneal_inflammation1.00068686
84MP0002693_abnormal_pancreas_physiology0.99275534
85MP0008995_early_reproductive_senescence0.98830729
86MP0002722_abnormal_immune_system0.98014063
87MP0009763_increased_sensitivity_to0.96918312
88MP0009333_abnormal_splenocyte_physiolog0.94986911
89MP0001485_abnormal_pinna_reflex0.93706540
90MP0005376_homeostasis/metabolism_phenot0.93242633
91MP0004147_increased_porphyrin_level0.92075245
92MP0005535_abnormal_body_temperature0.89239862
93MP0005379_endocrine/exocrine_gland_phen0.88693007
94MP0005084_abnormal_gallbladder_morpholo0.88613767
95MP0002405_respiratory_system_inflammati0.87555343
96MP0008873_increased_physiological_sensi0.86714255
97MP0001968_abnormal_touch/_nociception0.86561545
98MP0001851_eye_inflammation0.86384484
99MP0009642_abnormal_blood_homeostasis0.85444164
100MP0003638_abnormal_response/metabolism_0.85348473
101MP0008260_abnormal_autophagy0.85302008
102MP0002090_abnormal_vision0.85223550
103MP0002736_abnormal_nociception_after0.82354267
104MP0001756_abnormal_urination0.82050434
105MP0009765_abnormal_xenobiotic_induced0.81753613
106MP0003075_altered_response_to0.81428602
107MP0002254_reproductive_system_inflammat0.79544697
108MP0002102_abnormal_ear_morphology0.79030300
109MP0000358_abnormal_cell_content/0.78907926
110MP0003763_abnormal_thymus_physiology0.78455760
111MP0003787_abnormal_imprinting0.78022639
112MP0000716_abnormal_immune_system0.77835652
113MP0000490_abnormal_crypts_of0.77514278
114MP0002933_joint_inflammation0.77322302
115MP0003329_amyloid_beta_deposits0.76955140
116MP0002138_abnormal_hepatobiliary_system0.76861684
117MP0010386_abnormal_urinary_bladder0.75685387
118MP0005551_abnormal_eye_electrophysiolog0.74380439
119MP0003136_yellow_coat_color0.73931678
120MP0005253_abnormal_eye_physiology0.73630023
121MP0002638_abnormal_pupillary_reflex0.73163762
122MP0000749_muscle_degeneration0.73101770
123MP0003880_abnormal_central_pattern0.71670603
124MP0000689_abnormal_spleen_morphology0.71268519
125MP0005310_abnormal_salivary_gland0.70889034
126MP0005266_abnormal_metabolism0.70704604
127MP0003252_abnormal_bile_duct0.70576923
128MP0001661_extended_life_span0.70527790
129MP0001984_abnormal_olfaction0.70176188
130MP0010155_abnormal_intestine_physiology0.69123884
131MP0001919_abnormal_reproductive_system0.68381930
132MP0002429_abnormal_blood_cell0.67850954
133MP0008872_abnormal_physiological_respon0.67532846
134MP0000230_abnormal_systemic_arterial0.66939639
135MP0001663_abnormal_digestive_system0.66904052
136MP0001542_abnormal_bone_strength0.66509084
137MP0000598_abnormal_liver_morphology0.65473831
138MP0002136_abnormal_kidney_physiology0.65359942

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.70557231
2Hepatic necrosis (HP:0002605)4.41557105
3Mitochondrial inheritance (HP:0001427)4.40762010
4Hepatocellular necrosis (HP:0001404)4.36995849
5Acute encephalopathy (HP:0006846)4.36619124
6Abnormal mitochondria in muscle tissue (HP:0008316)4.35784084
7Increased CSF lactate (HP:0002490)3.86701903
8Abnormality of aromatic amino acid family metabolism (HP:0004338)3.86089948
9Progressive macrocephaly (HP:0004481)3.79798728
10Cerebral edema (HP:0002181)3.71659224
11Abnormality of cells of the erythroid lineage (HP:0012130)3.67503094
12Renal Fanconi syndrome (HP:0001994)3.57245132
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.50783451
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.50783451
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.46690689
16Lipid accumulation in hepatocytes (HP:0006561)3.46113745
17Increased hepatocellular lipid droplets (HP:0006565)3.45522242
18Generalized aminoaciduria (HP:0002909)3.32235689
19Increased intramyocellular lipid droplets (HP:0012240)3.30656348
20Increased muscle lipid content (HP:0009058)3.21420327
21Abnormal number of erythroid precursors (HP:0012131)3.16925593
223-Methylglutaconic aciduria (HP:0003535)3.09025378
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.08842347
24Lactic acidosis (HP:0003128)3.08225256
25Vacuolated lymphocytes (HP:0001922)3.00355701
26Recurrent abscess formation (HP:0002722)2.98306990
27Recurrent bacterial skin infections (HP:0005406)2.97773159
28Stomatitis (HP:0010280)2.91646845
29Respiratory failure (HP:0002878)2.90535370
30Dicarboxylic aciduria (HP:0003215)2.82390252
31Abnormality of dicarboxylic acid metabolism (HP:0010995)2.82390252
32Abnormality of fatty-acid metabolism (HP:0004359)2.81323626
33Increased serum lactate (HP:0002151)2.80933088
34Abnormality of glycolysis (HP:0004366)2.80634675
35Increased serum pyruvate (HP:0003542)2.80634675
36Aplastic anemia (HP:0001915)2.78751882
37Systemic lupus erythematosus (HP:0002725)2.75897427
38Lethargy (HP:0001254)2.75264522
39Parakeratosis (HP:0001036)2.66372405
40Exertional dyspnea (HP:0002875)2.60377735
41Leukodystrophy (HP:0002415)2.60183855
42Exercise intolerance (HP:0003546)2.59859227
43Prolonged partial thromboplastin time (HP:0003645)2.59745501
44Glycosuria (HP:0003076)2.56196107
45Abnormality of urine glucose concentration (HP:0011016)2.56196107
46Xanthomatosis (HP:0000991)2.55299880
47Eczematoid dermatitis (HP:0000976)2.54342877
48Recurrent gram-negative bacterial infections (HP:0005420)2.52572643
49Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.51735490
50Macrocytic anemia (HP:0001972)2.51262954
51Chronic obstructive pulmonary disease (HP:0006510)2.50111890
52Obstructive lung disease (HP:0006536)2.50111890
53Abnormality of glycolipid metabolism (HP:0010969)2.44152237
54Abnormality of liposaccharide metabolism (HP:0010968)2.44152237
55Abnormality of glycosphingolipid metabolism (HP:0004343)2.44152237
56Reticulocytopenia (HP:0001896)2.41510004
57Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.38507378
58IgM deficiency (HP:0002850)2.38327473
59Intrahepatic cholestasis (HP:0001406)2.35383332
60Abnormality of monocarboxylic acid metabolism (HP:0010996)2.34547761
61Hyperlipoproteinemia (HP:0010980)2.34390722
62Abnormality of macrophages (HP:0004311)2.33422665
63Optic disc pallor (HP:0000543)2.29860140
64Congenital ichthyosiform erythroderma (HP:0007431)2.28206272
65Type I transferrin isoform profile (HP:0003642)2.26420590
66Abnormality of renal resorption (HP:0011038)2.26042349
67CNS demyelination (HP:0007305)2.22912730
68Hypobetalipoproteinemia (HP:0003563)2.22877785
69Oral leukoplakia (HP:0002745)2.22767157
70Congenital, generalized hypertrichosis (HP:0004540)2.22729303
71Vomiting (HP:0002013)2.21001569
72Hyperammonemia (HP:0001987)2.19264432
73Elevated erythrocyte sedimentation rate (HP:0003565)2.17378990
74Ketosis (HP:0001946)2.17378210
75Pancytopenia (HP:0001876)2.17005811
76Mediastinal lymphadenopathy (HP:0100721)2.16427519
77Axonal loss (HP:0003447)2.15826611
78Spastic paraparesis (HP:0002313)2.13808812
79Hypoglycemic coma (HP:0001325)2.13470577
80Reduced antithrombin III activity (HP:0001976)2.12128082
81Methylmalonic aciduria (HP:0012120)2.11604207
82Purpura (HP:0000979)2.11009713
83Hyperphosphaturia (HP:0003109)2.10593734
84Respiratory difficulties (HP:0002880)2.08545220
85Myositis (HP:0100614)2.08191860
86Hepatosplenomegaly (HP:0001433)2.07603062
87Hypothermia (HP:0002045)2.07347932
88Opisthotonus (HP:0002179)2.06745612
89Recurrent skin infections (HP:0001581)2.05753016
90Emotional lability (HP:0000712)2.04349988
91Joint hemorrhage (HP:0005261)2.03621953
92Petechiae (HP:0000967)2.03172631
93Hypokinesia (HP:0002375)2.01374305
94Metabolic acidosis (HP:0001942)1.98168987
95Aplasia/Hypoplasia of the sacrum (HP:0008517)1.95397665
96Increased IgM level (HP:0003496)1.95318666
97Abnormality of serine family amino acid metabolism (HP:0010894)1.91987110
98Abnormality of glycine metabolism (HP:0010895)1.91987110
99Decreased electroretinogram (ERG) amplitude (HP:0000654)1.91296400
100Pallor (HP:0000980)1.88616047
101Brushfield spots (HP:0001088)1.87451552
102Delayed CNS myelination (HP:0002188)1.87156659
103Nausea (HP:0002018)1.84641676
104Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.83626037
105Neutropenia (HP:0001875)1.83011430
106Meningitis (HP:0001287)1.82315951
107Hyperglycinuria (HP:0003108)1.81217423
108Neuroendocrine neoplasm (HP:0100634)1.80657472
109Dysostosis multiplex (HP:0000943)1.80579950
110Deep venous thrombosis (HP:0002625)1.80203268
111Prolonged neonatal jaundice (HP:0006579)1.79895960
112Proximal tubulopathy (HP:0000114)1.79866762
113Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.79213239
114Abnormal protein N-linked glycosylation (HP:0012347)1.79213239
115Abnormal protein glycosylation (HP:0012346)1.79213239
116Abnormal glycosylation (HP:0012345)1.79213239
117Hyperbilirubinemia (HP:0002904)1.79183348
118Gliosis (HP:0002171)1.77574967
119Orchitis (HP:0100796)1.76737820
120Encephalitis (HP:0002383)1.76490014
121Cerebral palsy (HP:0100021)1.76429150
122Retrobulbar optic neuritis (HP:0100654)1.76237585
123Optic neuritis (HP:0100653)1.76237585
124Abnormal hemoglobin (HP:0011902)1.75902161
125Complement deficiency (HP:0004431)1.75900042
126Methylmalonic acidemia (HP:0002912)1.74874967
127Panhypogammaglobulinemia (HP:0003139)1.74797165
128Degeneration of anterior horn cells (HP:0002398)1.74573088
129Abnormality of the anterior horn cell (HP:0006802)1.74573088
130Recurrent fungal infections (HP:0002841)1.70896558
131Microvesicular hepatic steatosis (HP:0001414)1.70358375
132Pancreatic fibrosis (HP:0100732)1.70030307
133X-linked dominant inheritance (HP:0001423)1.69577661
134Pancreatic cysts (HP:0001737)1.67984687
135Hyperglycinemia (HP:0002154)1.67190789
136IgG deficiency (HP:0004315)1.66746030
137Increased cerebral lipofuscin (HP:0011813)1.65103939
138Increased neuronal autofluorescent lipopigment (HP:0002074)1.61592446
139Abnormal rod and cone electroretinograms (HP:0008323)1.61336657

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.66551724
2NME24.79398148
3BCKDK3.76151492
4TESK23.23361682
5STK162.99787359
6MAP3K122.98304774
7IRAK42.77713421
8PIM22.57504959
9BLK2.42638694
10ARAF2.27440657
11PBK2.18327705
12MYLK2.07506650
13LIMK12.06484803
14ZAK2.06277261
15IRAK31.88509000
16MST41.72458415
17EIF2AK31.67235475
18MAP4K11.61445380
19ERN11.58429240
20TESK11.57563277
21NME11.51183296
22TNK21.50593379
23TEC1.49558450
24BTK1.48629494
25ABL21.42925940
26KIT1.36251347
27GRK51.34638706
28NUAK11.32946707
29TBK11.27889824
30MAPKAPK51.27882936
31KDR1.27518893
32EPHB11.26260931
33ZAP701.24362498
34GRK71.24037964
35CDK191.23004461
36MAP3K111.21420670
37TXK1.19231165
38MST1R1.17686173
39OXSR11.17362603
40STK391.16466276
41SYK1.16417415
42TYK21.16413650
43MAP2K21.15036402
44MUSK1.15010528
45MAP4K21.14419730
46ILK1.12238532
47FES1.09771471
48VRK11.09621810
49LRRK21.05212879
50BUB11.00873986
51IKBKB0.98890026
52BRAF0.98080808
53GRK60.97306466
54DAPK30.96688363
55TAF10.92898453
56DAPK10.89727892
57PIK3CG0.87898694
58LYN0.86225116
59MAPK40.84026062
60IKBKE0.83320463
61WNK40.82908338
62WNK30.82386494
63IRAK20.81330740
64CSNK1G20.79209510
65RIPK40.75630338
66CSF1R0.75242553
67EIF2AK10.73860910
68ADRBK20.73504135
69FLT30.73351489
70MAP3K140.72617499
71MAP2K30.72399744
72TAOK10.69100969
73PDK20.68075107
74OBSCN0.67957884
75PRKCQ0.67160685
76LCK0.65020861
77IRAK10.64231352
78TRPM70.63755402
79TLK10.62949013
80MAP2K70.62021073
81SRPK10.61983334
82CAMK2G0.59283932
83RPS6KA60.58813437
84PRKCD0.57825669
85TNIK0.57744527
86CSNK1G30.57254541
87MAP3K30.55910575
88CSK0.55587497
89AURKA0.53673768
90MAPK150.53091902
91RPS6KC10.53090602
92RPS6KL10.53090602
93PASK0.53023168
94TAOK20.52191594
95PRKCI0.51870468
96CDC70.49504588
97PAK40.49414788
98TAOK30.49301201
99MAP2K60.48254636
100PLK30.48101123
101STK40.47784244
102ITK0.47574565
103BMPR1B0.47476368
104HCK0.46395200
105DYRK30.45490350
106CSNK1A1L0.45146018
107CAMK2D0.44902187
108MATK0.44782409
109BMPR20.43076559
110RPS6KA50.42887701
111MAPK120.41379672
112PINK10.41174957
113RPS6KB20.40947562
114PAK10.40097751
115CSNK2A10.38629042
116MARK30.38329876
117DYRK20.37042159
118MAP3K20.37014065
119PRKCG0.35673800
120PIM10.35516326
121CSNK2A20.34473746
122JAK30.34282094
123ADRBK10.34222217
124MAPKAPK30.34151516
125FGR0.34007913
126CSNK1G10.33982120
127CCNB10.32843627
128PKN10.31870079
129GRK10.30746489
130CLK10.30439381

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.08766237
2Ribosome_Homo sapiens_hsa030103.61284484
3Parkinsons disease_Homo sapiens_hsa050123.38736794
4Protein export_Homo sapiens_hsa030602.64395431
5Proteasome_Homo sapiens_hsa030502.56746825
6Alzheimers disease_Homo sapiens_hsa050102.44552794
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.39639618
8Fatty acid elongation_Homo sapiens_hsa000622.36742803
9Sulfur metabolism_Homo sapiens_hsa009202.18388606
10Huntingtons disease_Homo sapiens_hsa050162.12308309
11Primary bile acid biosynthesis_Homo sapiens_hsa001202.00352039
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.94198043
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.92982267
14Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.90688782
15Allograft rejection_Homo sapiens_hsa053301.87988210
16Peroxisome_Homo sapiens_hsa041461.83020467
17Autoimmune thyroid disease_Homo sapiens_hsa053201.81211110
18Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.76864622
19Histidine metabolism_Homo sapiens_hsa003401.73342720
20Pentose and glucuronate interconversions_Homo sapiens_hsa000401.73171736
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.72133078
22Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.68259941
23Steroid biosynthesis_Homo sapiens_hsa001001.67140043
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.66803853
25Type I diabetes mellitus_Homo sapiens_hsa049401.66243960
26Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.65304491
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.61477403
28Antigen processing and presentation_Homo sapiens_hsa046121.57199852
29Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.57163407
30Propanoate metabolism_Homo sapiens_hsa006401.56872730
31Chemical carcinogenesis_Homo sapiens_hsa052041.49586044
32Glutathione metabolism_Homo sapiens_hsa004801.47706925
33Fatty acid degradation_Homo sapiens_hsa000711.47173194
34RNA polymerase_Homo sapiens_hsa030201.46208458
35Mismatch repair_Homo sapiens_hsa034301.45180956
36Sulfur relay system_Homo sapiens_hsa041221.44723173
37Pyruvate metabolism_Homo sapiens_hsa006201.39233032
38Folate biosynthesis_Homo sapiens_hsa007901.38558645
39Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.34506694
40Intestinal immune network for IgA production_Homo sapiens_hsa046721.32521288
41Butanoate metabolism_Homo sapiens_hsa006501.31848503
42Staphylococcus aureus infection_Homo sapiens_hsa051501.31311772
43Base excision repair_Homo sapiens_hsa034101.26062098
44Drug metabolism - other enzymes_Homo sapiens_hsa009831.23452210
45Tryptophan metabolism_Homo sapiens_hsa003801.19872183
46Other glycan degradation_Homo sapiens_hsa005111.19793033
47Pentose phosphate pathway_Homo sapiens_hsa000301.18992834
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.18359218
49Phenylalanine metabolism_Homo sapiens_hsa003601.16439690
50Steroid hormone biosynthesis_Homo sapiens_hsa001401.13367522
51beta-Alanine metabolism_Homo sapiens_hsa004101.12807964
52Fatty acid metabolism_Homo sapiens_hsa012121.10149870
53Carbon metabolism_Homo sapiens_hsa012001.08398881
54Tyrosine metabolism_Homo sapiens_hsa003501.08180164
55Complement and coagulation cascades_Homo sapiens_hsa046101.07532893
56Cyanoamino acid metabolism_Homo sapiens_hsa004601.05530678
57Spliceosome_Homo sapiens_hsa030401.04216341
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.03917277
59Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.99430478
60Metabolic pathways_Homo sapiens_hsa011000.96244998
61Pyrimidine metabolism_Homo sapiens_hsa002400.93959664
62Collecting duct acid secretion_Homo sapiens_hsa049660.93854257
63Cardiac muscle contraction_Homo sapiens_hsa042600.93823233
64Caffeine metabolism_Homo sapiens_hsa002320.93262389
65Retinol metabolism_Homo sapiens_hsa008300.91388325
66Arachidonic acid metabolism_Homo sapiens_hsa005900.90695767
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.88305489
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87768047
69Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.85610012
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.84507100
71Hematopoietic cell lineage_Homo sapiens_hsa046400.83124834
72PPAR signaling pathway_Homo sapiens_hsa033200.82581296
73Starch and sucrose metabolism_Homo sapiens_hsa005000.82115683
74Arginine and proline metabolism_Homo sapiens_hsa003300.81789582
75Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.77968336
76Arginine biosynthesis_Homo sapiens_hsa002200.77084967
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.76848204
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76746766
79SNARE interactions in vesicular transport_Homo sapiens_hsa041300.75116874
80Lysosome_Homo sapiens_hsa041420.74749802
81Cysteine and methionine metabolism_Homo sapiens_hsa002700.71255223
82Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70575010
83Linoleic acid metabolism_Homo sapiens_hsa005910.70518468
84Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69752233
85Nucleotide excision repair_Homo sapiens_hsa034200.68856947
86Biosynthesis of amino acids_Homo sapiens_hsa012300.66378345
87Systemic lupus erythematosus_Homo sapiens_hsa053220.65931461
88RNA degradation_Homo sapiens_hsa030180.63633212
89Rheumatoid arthritis_Homo sapiens_hsa053230.62520040
90Vibrio cholerae infection_Homo sapiens_hsa051100.62220763
91Phagosome_Homo sapiens_hsa041450.62208213
92Ether lipid metabolism_Homo sapiens_hsa005650.61433453
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.59852801
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.59756211
95Epstein-Barr virus infection_Homo sapiens_hsa051690.59419765
96Fanconi anemia pathway_Homo sapiens_hsa034600.57738057
97Fat digestion and absorption_Homo sapiens_hsa049750.55118541
98Tuberculosis_Homo sapiens_hsa051520.54132852
99alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.52722998
100Viral myocarditis_Homo sapiens_hsa054160.52580245
101Nitrogen metabolism_Homo sapiens_hsa009100.52303927
102Legionellosis_Homo sapiens_hsa051340.51652071
103Galactose metabolism_Homo sapiens_hsa000520.50670271
104Vitamin B6 metabolism_Homo sapiens_hsa007500.50258677
105Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49803561
106Fructose and mannose metabolism_Homo sapiens_hsa000510.49327045
107Basal transcription factors_Homo sapiens_hsa030220.49054401
108Glycosaminoglycan degradation_Homo sapiens_hsa005310.47809200
109Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44878280
110Sphingolipid metabolism_Homo sapiens_hsa006000.44731863
111Pertussis_Homo sapiens_hsa051330.43037475
112Phototransduction_Homo sapiens_hsa047440.38150440
113Regulation of autophagy_Homo sapiens_hsa041400.37860940
114Osteoclast differentiation_Homo sapiens_hsa043800.37742237
115Selenocompound metabolism_Homo sapiens_hsa004500.36763219
116Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.36498647
117Purine metabolism_Homo sapiens_hsa002300.35862810
118Malaria_Homo sapiens_hsa051440.34510824
119Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.34200240
120One carbon pool by folate_Homo sapiens_hsa006700.34196757
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33960098
122NOD-like receptor signaling pathway_Homo sapiens_hsa046210.33775491
123Glycerolipid metabolism_Homo sapiens_hsa005610.33590522
124Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33217120
125Leishmaniasis_Homo sapiens_hsa051400.33174321
126Herpes simplex infection_Homo sapiens_hsa051680.32977058
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32776812
128ABC transporters_Homo sapiens_hsa020100.31622126
129Graft-versus-host disease_Homo sapiens_hsa053320.31434049
130Asthma_Homo sapiens_hsa053100.31108584
131Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30542135
132Vitamin digestion and absorption_Homo sapiens_hsa049770.30399561
133Salmonella infection_Homo sapiens_hsa051320.27498125
134Shigellosis_Homo sapiens_hsa051310.26585928
135RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.26313991
136Synaptic vesicle cycle_Homo sapiens_hsa047210.25733729
137Toll-like receptor signaling pathway_Homo sapiens_hsa046200.24551687
138RNA transport_Homo sapiens_hsa030130.23480433
139DNA replication_Homo sapiens_hsa030300.19660550
140Primary immunodeficiency_Homo sapiens_hsa053400.18262420
141Homologous recombination_Homo sapiens_hsa034400.16983452

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