LAMTOR5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.39380540
2energy coupled proton transport, down electrochemical gradient (GO:0015985)6.97834530
3ATP synthesis coupled proton transport (GO:0015986)6.97834530
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.81216036
5respiratory electron transport chain (GO:0022904)5.95581064
6electron transport chain (GO:0022900)5.81443274
7protein neddylation (GO:0045116)5.63706286
8chaperone-mediated protein transport (GO:0072321)5.37598259
9protein complex biogenesis (GO:0070271)4.87854344
10mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.85285588
11mitochondrial respiratory chain complex I assembly (GO:0032981)4.85285588
12NADH dehydrogenase complex assembly (GO:0010257)4.85285588
13proteasome assembly (GO:0043248)4.59637146
14negative regulation of telomere maintenance (GO:0032205)4.41850797
15axon ensheathment in central nervous system (GO:0032291)4.37264710
16central nervous system myelination (GO:0022010)4.37264710
17mitochondrial respiratory chain complex assembly (GO:0033108)4.33215238
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.19006510
19ribosomal small subunit biogenesis (GO:0042274)4.14272363
20DNA damage response, detection of DNA damage (GO:0042769)4.00726448
21GTP biosynthetic process (GO:0006183)3.88596934
22regulation of cellular amino acid metabolic process (GO:0006521)3.87802358
23antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.84995262
24respiratory chain complex IV assembly (GO:0008535)3.83285439
25fatty acid elongation (GO:0030497)3.78232347
26hydrogen ion transmembrane transport (GO:1902600)3.75153556
27tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.73973909
28RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.73973909
29negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.73589262
30cotranslational protein targeting to membrane (GO:0006613)3.72591664
31termination of RNA polymerase III transcription (GO:0006386)3.70235713
32transcription elongation from RNA polymerase III promoter (GO:0006385)3.70235713
33ribosomal small subunit assembly (GO:0000028)3.67516934
34antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.65835228
35cytochrome complex assembly (GO:0017004)3.64746198
36viral transcription (GO:0019083)3.60997283
37protein targeting to ER (GO:0045047)3.60768503
38SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.59900012
39DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.57835528
40nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.57101083
41water-soluble vitamin biosynthetic process (GO:0042364)3.55738593
427-methylguanosine mRNA capping (GO:0006370)3.55730382
43protein localization to endoplasmic reticulum (GO:0070972)3.54139339
44sequestering of actin monomers (GO:0042989)3.54043134
45protein targeting to mitochondrion (GO:0006626)3.53445539
46ribosomal large subunit biogenesis (GO:0042273)3.52890285
47regulation of helicase activity (GO:0051095)3.51694383
487-methylguanosine RNA capping (GO:0009452)3.51240996
49RNA capping (GO:0036260)3.51240996
50intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.49270532
51signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.49270532
52purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.48682639
53negative regulation of ligase activity (GO:0051352)3.48460000
54negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.48460000
55proton transport (GO:0015992)3.46843209
56translational termination (GO:0006415)3.46329542
57signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.45627075
58signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.45627075
59signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.45627075
60exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.45168096
61protein-cofactor linkage (GO:0018065)3.43699593
62L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.43501032
63establishment of protein localization to mitochondrion (GO:0072655)3.43302976
64establishment of protein localization to endoplasmic reticulum (GO:0072599)3.42547542
65purine nucleoside triphosphate biosynthetic process (GO:0009145)3.42453351
66mannosylation (GO:0097502)3.40953494
67hydrogen transport (GO:0006818)3.38082464
68ATP biosynthetic process (GO:0006754)3.37278555
69positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.31915903
70intracellular protein transmembrane import (GO:0044743)3.30470226
71signal transduction involved in DNA damage checkpoint (GO:0072422)3.29904827
72signal transduction involved in DNA integrity checkpoint (GO:0072401)3.29904827
73signal peptide processing (GO:0006465)3.28814087
74GPI anchor biosynthetic process (GO:0006506)3.28122004
75long-chain fatty acid biosynthetic process (GO:0042759)3.26791049
76signal transduction involved in cell cycle checkpoint (GO:0072395)3.26557108
77platelet dense granule organization (GO:0060155)3.25430377
78regulation of mitochondrial translation (GO:0070129)3.24269301
79protein localization to mitochondrion (GO:0070585)3.18674314
80negative regulation of telomerase activity (GO:0051974)3.15101676
81regulation of cellular amine metabolic process (GO:0033238)3.15006380
82cellular component biogenesis (GO:0044085)3.13058917
83translation (GO:0006412)3.12780965
84regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.11623448
85cullin deneddylation (GO:0010388)3.11131123
86UTP biosynthetic process (GO:0006228)3.10273180
87guanosine-containing compound biosynthetic process (GO:1901070)3.09383901
88oxidative phosphorylation (GO:0006119)3.09192982
89translational initiation (GO:0006413)3.07564589
90nucleoside triphosphate biosynthetic process (GO:0009142)3.05662579
91ribonucleoside triphosphate biosynthetic process (GO:0009201)3.05570567
92pseudouridine synthesis (GO:0001522)3.05365439
93regulation of telomere maintenance via telomerase (GO:0032210)3.03508436
94establishment of viral latency (GO:0019043)3.02910282
95rRNA modification (GO:0000154)2.99912975
96inner mitochondrial membrane organization (GO:0007007)2.97900144
97dopamine transport (GO:0015872)2.95610512
98protein deneddylation (GO:0000338)2.94489117
99deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.93083421
100nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.91652116
101energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.91481874
102ATP hydrolysis coupled proton transport (GO:0015991)2.91481874
103antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.90847960
104anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.90437680
105establishment of integrated proviral latency (GO:0075713)2.90074829
106viral life cycle (GO:0019058)2.89844127
107substantia nigra development (GO:0021762)2.89828568
108translational elongation (GO:0006414)2.87911400
109maturation of 5.8S rRNA (GO:0000460)2.86584923
110aerobic respiration (GO:0009060)2.82020516
111CTP metabolic process (GO:0046036)2.81910235
112CTP biosynthetic process (GO:0006241)2.81910235
113GPI anchor metabolic process (GO:0006505)2.80583827
114DNA deamination (GO:0045006)2.80468098
115cellular protein complex disassembly (GO:0043624)2.79588274
116neutrophil activation involved in immune response (GO:0002283)2.79105293
117behavioral response to nicotine (GO:0035095)2.79045924
118peptidyl-histidine modification (GO:0018202)2.78508253
119mitochondrial transport (GO:0006839)2.78163681
120preassembly of GPI anchor in ER membrane (GO:0016254)2.77482640
121maturation of SSU-rRNA (GO:0030490)2.76681663
122pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.74851800
123positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.74654584
124positive regulation of ligase activity (GO:0051351)2.73691612
125nucleotide transmembrane transport (GO:1901679)2.72546755
126tRNA processing (GO:0008033)2.67828782
127protein targeting to membrane (GO:0006612)2.65126241

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.10411815
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.63762255
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.49679066
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.13368783
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.97959786
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.92814705
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.89364834
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.69032109
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.21982970
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.11698507
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.07330384
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.06290066
13PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.64450668
14SRF_21415370_ChIP-Seq_HL-1_Mouse2.61196690
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.54120122
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.53837649
17VDR_23849224_ChIP-Seq_CD4+_Human2.32363496
18ZNF274_21170338_ChIP-Seq_K562_Hela2.29271146
19VDR_22108803_ChIP-Seq_LS180_Human2.19418351
20ELK1_19687146_ChIP-ChIP_HELA_Human2.10794951
21BP1_19119308_ChIP-ChIP_Hs578T_Human2.07240490
22MYC_18555785_ChIP-Seq_MESCs_Mouse1.97034538
23DCP1A_22483619_ChIP-Seq_HELA_Human1.91438322
24MYC_18358816_ChIP-ChIP_MESCs_Mouse1.91055190
25THAP11_20581084_ChIP-Seq_MESCs_Mouse1.89587024
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.88241379
27CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.86597264
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.86274254
29TAF15_26573619_Chip-Seq_HEK293_Human1.84404812
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.79789922
31YY1_21170310_ChIP-Seq_MESCs_Mouse1.78045907
32FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.74106965
33IRF8_21731497_ChIP-ChIP_J774_Mouse1.72603226
34E2F1_18555785_ChIP-Seq_MESCs_Mouse1.70406090
35FOXP3_21729870_ChIP-Seq_TREG_Human1.64614189
36HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63967953
37IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.57582049
38ELK1_22589737_ChIP-Seq_MCF10A_Human1.57335163
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.56156844
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54633319
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.47530874
42IRF1_19129219_ChIP-ChIP_H3396_Human1.47098064
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.45068178
44MYC_19030024_ChIP-ChIP_MESCs_Mouse1.43002104
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.42731742
46E2F4_17652178_ChIP-ChIP_JURKAT_Human1.41123492
47TP53_22573176_ChIP-Seq_HFKS_Human1.38842757
48SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.34285764
49TTF2_22483619_ChIP-Seq_HELA_Human1.34099773
50XRN2_22483619_ChIP-Seq_HELA_Human1.33211284
51FUS_26573619_Chip-Seq_HEK293_Human1.31989689
52GABP_19822575_ChIP-Seq_HepG2_Human1.28611264
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.27268531
54CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26920299
55ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25681891
56GBX2_23144817_ChIP-Seq_PC3_Human1.24291504
57BMI1_23680149_ChIP-Seq_NPCS_Mouse1.23253640
58ER_23166858_ChIP-Seq_MCF-7_Human1.18318592
59POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18200014
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.14783742
61ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09229858
62HTT_18923047_ChIP-ChIP_STHdh_Human1.08749152
63PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08412964
64FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.08353618
65MYC_18940864_ChIP-ChIP_HL60_Human1.07993752
66IGF1R_20145208_ChIP-Seq_DFB_Human1.07657096
67EZH2_22144423_ChIP-Seq_EOC_Human1.06304924
68PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.04309333
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.02529406
70CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01101427
71HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.00460847
72MYC_19079543_ChIP-ChIP_MESCs_Mouse1.00058225
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.99116733
74CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98495839
75AR_20517297_ChIP-Seq_VCAP_Human0.98224460
76FLI1_27457419_Chip-Seq_LIVER_Mouse0.98084445
77MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.97960541
78FOXA1_25329375_ChIP-Seq_VCAP_Human0.97564166
79FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97564166
80SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97309409
81NELFA_20434984_ChIP-Seq_ESCs_Mouse0.97210074
82GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96380756
83SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.96032344
84LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.95070136
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.94663218
86STAT4_19710469_ChIP-ChIP_TH1__Mouse0.93172781
87NCOR_22424771_ChIP-Seq_293T_Human0.92272894
88CTCF_18555785_ChIP-Seq_MESCs_Mouse0.90966885
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.90311954
90TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.90237671
91EWS_26573619_Chip-Seq_HEK293_Human0.89716314
92SOX2_16153702_ChIP-ChIP_HESCs_Human0.88379039
93KDM5A_27292631_Chip-Seq_BREAST_Human0.87525640
94BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86615715
95STAT1_20625510_ChIP-Seq_HELA_Human0.86295802
96SPI1_23547873_ChIP-Seq_NB4_Human0.85314581
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.84611043
98FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.84588341
99CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.84112843
100DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.82795745
101P300_19829295_ChIP-Seq_ESCs_Human0.82710437
102IRF8_22096565_ChIP-ChIP_GC-B_Human0.82124883
103RNF2_27304074_Chip-Seq_NSC_Mouse0.80388681
104CTBP1_25329375_ChIP-Seq_LNCAP_Human0.80127475
105POU5F1_16153702_ChIP-ChIP_HESCs_Human0.80005624
106ETV2_25802403_ChIP-Seq_MESCs_Mouse0.79527232
107NANOG_16153702_ChIP-ChIP_HESCs_Human0.79389494
108GATA3_21878914_ChIP-Seq_MCF-7_Human0.79147995
109CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.78999052
110GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.78373441
111TAL1_26923725_Chip-Seq_HPCs_Mouse0.78014609
112MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.77891959
113YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.77708547
114PADI4_21655091_ChIP-ChIP_MCF-7_Human0.76365515
115STAT3_18555785_Chip-Seq_ESCs_Mouse0.75831722
116ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.75634050
117POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.74798384
118OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.74273406
119NANOG_19829295_ChIP-Seq_ESCs_Human0.73787013
120SOX2_19829295_ChIP-Seq_ESCs_Human0.73787013
121PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.73539709
122POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.73100040
123SALL4_22934838_ChIP-ChIP_CD34+_Human0.71148257
124SUZ12_18555785_Chip-Seq_ESCs_Mouse0.69151755
125CBX2_27304074_Chip-Seq_ESCs_Mouse0.68762017
126MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.68037585

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization3.75684602
2MP0003880_abnormal_central_pattern3.68714749
3MP0001905_abnormal_dopamine_level3.47402168
4MP0009379_abnormal_foot_pigmentation3.29637167
5MP0006072_abnormal_retinal_apoptosis2.55831106
6MP0001986_abnormal_taste_sensitivity2.37364792
7MP0000920_abnormal_myelination2.35993278
8MP0003136_yellow_coat_color2.34334808
9MP0004133_heterotaxia2.31480621
10MP0005171_absent_coat_pigmentation2.23907822
11MP0002148_abnormal_hypersensitivity_rea2.18831908
12MP0000372_irregular_coat_pigmentation2.17420174
13MP0003011_delayed_dark_adaptation2.17228410
14MP0002837_dystrophic_cardiac_calcinosis2.10562300
15MP0003724_increased_susceptibility_to2.06805426
16MP0006276_abnormal_autonomic_nervous2.02095227
17MP0003186_abnormal_redox_activity2.00582978
18MP0004142_abnormal_muscle_tone1.99354496
19MP0009785_altered_susceptibility_to1.96493243
20MP0002736_abnormal_nociception_after1.95216352
21MP0005084_abnormal_gallbladder_morpholo1.94886528
22MP0002163_abnormal_gland_morphology1.91419046
23MP0002638_abnormal_pupillary_reflex1.84229521
24MP0002272_abnormal_nervous_system1.78821896
25MP0008058_abnormal_DNA_repair1.77731011
26MP0008875_abnormal_xenobiotic_pharmacok1.77429743
27MP0004742_abnormal_vestibular_system1.74934376
28MP0001188_hyperpigmentation1.73539417
29MP0005671_abnormal_response_to1.71722136
30MP0004147_increased_porphyrin_level1.68173910
31MP0001835_abnormal_antigen_presentation1.67055113
32MP0006036_abnormal_mitochondrial_physio1.66202942
33MP0001968_abnormal_touch/_nociception1.65843925
34MP0008260_abnormal_autophagy1.64787728
35MP0008995_early_reproductive_senescence1.63574982
36MP0005253_abnormal_eye_physiology1.63361392
37MP0008877_abnormal_DNA_methylation1.62878062
38MP0005379_endocrine/exocrine_gland_phen1.61208037
39MP0010386_abnormal_urinary_bladder1.60774393
40MP0009046_muscle_twitch1.57309414
41MP0000631_abnormal_neuroendocrine_gland1.56127736
42MP0002064_seizures1.55106436
43MP0002734_abnormal_mechanical_nocicepti1.51882268
44MP0002735_abnormal_chemical_nociception1.45056855
45MP0009745_abnormal_behavioral_response1.44259892
46MP0003121_genomic_imprinting1.39179072
47MP0003646_muscle_fatigue1.38912197
48MP0005408_hypopigmentation1.38907718
49MP0002653_abnormal_ependyma_morphology1.38739127
50MP0005409_darkened_coat_color1.38280109
51MP0005000_abnormal_immune_tolerance1.37426776
52MP0001984_abnormal_olfaction1.36636920
53MP0001970_abnormal_pain_threshold1.35513014
54MP0005646_abnormal_pituitary_gland1.35190975
55MP0006082_CNS_inflammation1.35149429
56MP0005423_abnormal_somatic_nervous1.33297225
57MP0002277_abnormal_respiratory_mucosa1.32099123
58MP0006035_abnormal_mitochondrial_morpho1.32089673
59MP0004270_analgesia1.31864010
60MP0001440_abnormal_grooming_behavior1.31441204
61MP0005025_abnormal_response_to1.27360615
62MP0003122_maternal_imprinting1.21728664
63MP0003950_abnormal_plasma_membrane1.20695734
64MP0002876_abnormal_thyroid_physiology1.20613698
65MP0001727_abnormal_embryo_implantation1.18418059
66MP0004381_abnormal_hair_follicle1.18025602
67MP0001764_abnormal_homeostasis1.17698510
68MP0001486_abnormal_startle_reflex1.17311524
69MP0001485_abnormal_pinna_reflex1.16888865
70MP0002234_abnormal_pharynx_morphology1.16476995
71MP0002938_white_spotting1.16141835
72MP0002572_abnormal_emotion/affect_behav1.13481948
73MP0002419_abnormal_innate_immunity1.13175657
74MP0001501_abnormal_sleep_pattern1.13033606
75MP0008872_abnormal_physiological_respon1.12569956
76MP0005410_abnormal_fertilization1.11683798
77MP0002557_abnormal_social/conspecific_i1.11073848
78MP0001542_abnormal_bone_strength1.10981620
79MP0003786_premature_aging1.09781083
80MP0004145_abnormal_muscle_electrophysio1.09398437
81MP0003806_abnormal_nucleotide_metabolis1.09260237
82MP0000015_abnormal_ear_pigmentation1.09174087
83MP0002067_abnormal_sensory_capabilities1.08484946
84MP0005195_abnormal_posterior_eye1.07737212
85MP0002733_abnormal_thermal_nociception1.06975386
86MP0003718_maternal_effect1.06474033
87MP0005394_taste/olfaction_phenotype1.05858340
88MP0005499_abnormal_olfactory_system1.05858340
89MP0009333_abnormal_splenocyte_physiolog1.05829586
90MP0003890_abnormal_embryonic-extraembry1.05797303
91MP0003137_abnormal_impulse_conducting1.03682270
92MP0006292_abnormal_olfactory_placode1.02324142
93MP0001853_heart_inflammation1.00129340
94MP0005386_behavior/neurological_phenoty0.99726190
95MP0004924_abnormal_behavior0.99726190
96MP0002229_neurodegeneration0.97636288
97MP0002160_abnormal_reproductive_system0.97536446
98MP0002723_abnormal_immune_serum0.97389425
99MP0002095_abnormal_skin_pigmentation0.97321124
100MP0008775_abnormal_heart_ventricle0.97025303
101MP0000647_abnormal_sebaceous_gland0.96283685
102MP0005332_abnormal_amino_acid0.95481213
103MP0003329_amyloid_beta_deposits0.92896659
104MP0001963_abnormal_hearing_physiology0.91823525
105MP0001790_abnormal_immune_system0.91398715
106MP0005387_immune_system_phenotype0.91398715
107MP0005075_abnormal_melanosome_morpholog0.90597145
108MP0003787_abnormal_imprinting0.90536374
109MP0005551_abnormal_eye_electrophysiolog0.90046955
110MP0005389_reproductive_system_phenotype0.89941060
111MP0002090_abnormal_vision0.89893862
112MP0008789_abnormal_olfactory_epithelium0.88538573
113MP0003634_abnormal_glial_cell0.87888511
114MP0001293_anophthalmia0.87760458
115MP0003690_abnormal_glial_cell0.87500636
116MP0005636_abnormal_mineral_homeostasis0.86161772
117MP0002420_abnormal_adaptive_immunity0.85902126
118MP0002210_abnormal_sex_determination0.85539010
119MP0003656_abnormal_erythrocyte_physiolo0.84765531
120MP0003635_abnormal_synaptic_transmissio0.84736623
121MP0001819_abnormal_immune_cell0.84597573
122MP0002752_abnormal_somatic_nervous0.83541814
123MP0004215_abnormal_myocardial_fiber0.81295982
124MP0002452_abnormal_antigen_presenting0.80318603
125MP0005058_abnormal_lysosome_morphology0.79976693
126MP0003195_calcinosis0.78650611
127MP0005164_abnormal_response_to0.77978273
128MP0002928_abnormal_bile_duct0.76144156
129MP0002822_catalepsy0.75545470
130MP0009697_abnormal_copulation0.75081456
131MP0008932_abnormal_embryonic_tissue0.74794217
132MP0001919_abnormal_reproductive_system0.74204375
133MP0001324_abnormal_eye_pigmentation0.73908415
134MP0000026_abnormal_inner_ear0.73604331
135MP0005645_abnormal_hypothalamus_physiol0.73505619
136MP0002102_abnormal_ear_morphology0.73492603
137MP0000778_abnormal_nervous_system0.72888060
138MP0000049_abnormal_middle_ear0.72464330
139MP0005391_vision/eye_phenotype0.71765589
140MP0002751_abnormal_autonomic_nervous0.71507011
141MP0002184_abnormal_innervation0.71320820
142MP0002295_abnormal_pulmonary_circulatio0.71285845
143MP0003938_abnormal_ear_development0.71209904
144MP0002063_abnormal_learning/memory/cond0.70430085
145MP0004043_abnormal_pH_regulation0.70206309
146MP0002332_abnormal_exercise_endurance0.70168063
147MP0002132_abnormal_respiratory_system0.69858890
148MP0001929_abnormal_gametogenesis0.68256847

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.53378644
2Mitochondrial inheritance (HP:0001427)5.90138434
3Abnormal mitochondria in muscle tissue (HP:0008316)5.83578722
4Progressive macrocephaly (HP:0004481)5.44588217
5Acute encephalopathy (HP:0006846)5.20572370
6Increased hepatocellular lipid droplets (HP:0006565)5.01380956
7Hepatocellular necrosis (HP:0001404)4.95016156
8Increased CSF lactate (HP:0002490)4.94022604
9Renal Fanconi syndrome (HP:0001994)4.70245687
103-Methylglutaconic aciduria (HP:0003535)4.49416453
11Lipid accumulation in hepatocytes (HP:0006561)4.37962005
12Hepatic necrosis (HP:0002605)4.27494828
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.13205794
14Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.06441244
15Increased intramyocellular lipid droplets (HP:0012240)3.69550913
16Exertional dyspnea (HP:0002875)3.68236400
17Parakeratosis (HP:0001036)3.64447118
18Increased serum pyruvate (HP:0003542)3.62169538
19Abnormality of glycolysis (HP:0004366)3.62169538
20Leukodystrophy (HP:0002415)3.59791344
21Decreased activity of mitochondrial respiratory chain (HP:0008972)3.56441420
22Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.56441420
23Exercise intolerance (HP:0003546)3.47004988
24Respiratory failure (HP:0002878)3.44570622
25Optic disc pallor (HP:0000543)3.41293021
26Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.41254543
27Cerebral edema (HP:0002181)3.35572617
28Increased serum lactate (HP:0002151)3.30725838
29Abnormality of renal resorption (HP:0011038)3.29618154
30Lactic acidosis (HP:0003128)3.26303704
31Abnormality of cells of the erythroid lineage (HP:0012130)3.18275232
32Hypothermia (HP:0002045)3.09748051
33Molar tooth sign on MRI (HP:0002419)3.09714092
34Abnormality of midbrain morphology (HP:0002418)3.09714092
35Increased muscle lipid content (HP:0009058)3.00406732
36Pancreatic cysts (HP:0001737)2.98659616
37True hermaphroditism (HP:0010459)2.91666930
38Abnormal number of erythroid precursors (HP:0012131)2.82024893
39Respiratory difficulties (HP:0002880)2.79156239
40Congenital, generalized hypertrichosis (HP:0004540)2.57700618
41Type I transferrin isoform profile (HP:0003642)2.52361951
42Neuroendocrine neoplasm (HP:0100634)2.49403955
43Generalized aminoaciduria (HP:0002909)2.45909367
44Cerebral hypomyelination (HP:0006808)2.45131484
45Aplastic anemia (HP:0001915)2.39941727
46Nephronophthisis (HP:0000090)2.36017520
47Macrocytic anemia (HP:0001972)2.34738497
48Congenital ichthyosiform erythroderma (HP:0007431)2.32985896
49Retinal dysplasia (HP:0007973)2.32950841
50Medial flaring of the eyebrow (HP:0010747)2.27397496
51Abnormality of urine glucose concentration (HP:0011016)2.26674639
52Glycosuria (HP:0003076)2.26674639
53X-linked dominant inheritance (HP:0001423)2.26399297
54Hyperglycinemia (HP:0002154)2.15010589
55Sclerocornea (HP:0000647)2.13697418
56Reticulocytopenia (HP:0001896)2.10732419
57Pheochromocytoma (HP:0002666)2.09274957
58CNS demyelination (HP:0007305)2.08470047
59Hyperphosphaturia (HP:0003109)2.08452799
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.07006953
61Microvesicular hepatic steatosis (HP:0001414)2.06592791
62Abnormal hair whorl (HP:0010721)2.04069866
63Amniotic constriction ring (HP:0009775)2.03045426
64Abnormality of placental membranes (HP:0011409)2.03045426
65Emotional lability (HP:0000712)1.97873420
66Congenital primary aphakia (HP:0007707)1.95201536
67Nephrogenic diabetes insipidus (HP:0009806)1.94357661
68Gait imbalance (HP:0002141)1.93575724
69Patchy hypopigmentation of hair (HP:0011365)1.93289199
70Renal tubular dysfunction (HP:0000124)1.91820735
71Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.91731683
72Abnormal protein N-linked glycosylation (HP:0012347)1.91731683
73Abnormal protein glycosylation (HP:0012346)1.91731683
74Abnormal glycosylation (HP:0012345)1.91731683
75Abnormality of alanine metabolism (HP:0010916)1.89440281
76Hyperalaninemia (HP:0003348)1.89440281
77Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89440281
78Oral leukoplakia (HP:0002745)1.88527223
79Recurrent abscess formation (HP:0002722)1.88197712
80Vacuolated lymphocytes (HP:0001922)1.87632223
81Abnormality of the labia minora (HP:0012880)1.86854741
82Type II lissencephaly (HP:0007260)1.84964726
83Dicarboxylic aciduria (HP:0003215)1.84603557
84Abnormality of dicarboxylic acid metabolism (HP:0010995)1.84603557
85Esophageal atresia (HP:0002032)1.84148822
86Male pseudohermaphroditism (HP:0000037)1.84022782
87Abnormality of the renal medulla (HP:0100957)1.83516120
88Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.82612050
89Degeneration of the lateral corticospinal tracts (HP:0002314)1.82612050
90Methylmalonic acidemia (HP:0002912)1.82566360
91Pallor (HP:0000980)1.82141224
92Cerebral hemorrhage (HP:0001342)1.80997348
93Limb dystonia (HP:0002451)1.80297655
94Methylmalonic aciduria (HP:0012120)1.79943926
95Myokymia (HP:0002411)1.76615054
96Congenital stationary night blindness (HP:0007642)1.75725780
97Aplasia/Hypoplasia of the fovea (HP:0008060)1.75259153
98Hypoplasia of the fovea (HP:0007750)1.75259153
99Abnormality of vitamin B metabolism (HP:0004340)1.75131158
100Sensory axonal neuropathy (HP:0003390)1.74793294
101Degeneration of anterior horn cells (HP:0002398)1.74373767
102Abnormality of the anterior horn cell (HP:0006802)1.74373767
103Hepatosplenomegaly (HP:0001433)1.71871988
104Vaginal atresia (HP:0000148)1.71827524
105Abnormality of macrophages (HP:0004311)1.71740588
106Septo-optic dysplasia (HP:0100842)1.71699861
107Autoamputation (HP:0001218)1.70992350
108Abnormality of the axillary hair (HP:0100134)1.70789210
109Abnormality of secondary sexual hair (HP:0009888)1.70789210
110Genital tract atresia (HP:0001827)1.70786339
111Abnormal urine phosphate concentration (HP:0012599)1.70766047
112Blindness (HP:0000618)1.69872806
113Colon cancer (HP:0003003)1.69322396
114Abnormal pupillary function (HP:0007686)1.69129168
115Abnormality of serum amino acid levels (HP:0003112)1.68614680
116Stenosis of the external auditory canal (HP:0000402)1.68131452
117Neurofibrillary tangles (HP:0002185)1.68047120
118Type 2 muscle fiber atrophy (HP:0003554)1.67788918
119Aplasia/hypoplasia of the uterus (HP:0008684)1.64780795
120Lethargy (HP:0001254)1.64412259
121CNS hypomyelination (HP:0003429)1.64185464
122Optic nerve hypoplasia (HP:0000609)1.64029086
123Chronic hepatic failure (HP:0100626)1.63596669
124Aplasia/Hypoplasia of the tongue (HP:0010295)1.63005489
125Abnormality of the vitamin B12 metabolism (HP:0004341)1.62975759
126Gastrointestinal atresia (HP:0002589)1.61542209
127Abnormality of aromatic amino acid family metabolism (HP:0004338)1.60369518
128Recurrent bacterial skin infections (HP:0005406)1.60126830
129Renal cortical cysts (HP:0000803)1.59484228
130Postnatal microcephaly (HP:0005484)1.59082430
131Pancreatic fibrosis (HP:0100732)1.58562600
132Increased IgM level (HP:0003496)1.58384905
133Poor head control (HP:0002421)1.58304691
134Poor suck (HP:0002033)1.58198175
135White forelock (HP:0002211)1.57914219
136Elevated erythrocyte sedimentation rate (HP:0003565)1.56767739
137Hypomagnesemia (HP:0002917)1.54992961
138Metaphyseal dysplasia (HP:0100255)1.53953246
139Spastic paraparesis (HP:0002313)1.53914528
140Hypokinesia (HP:0002375)1.53813309

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK23.70540360
2VRK23.52518990
3PBK3.39760833
4STK163.37806303
5MAP4K23.09549006
6NME22.88144820
7MAP2K62.79044554
8MAP3K122.69723514
9ARAF2.60243107
10STK392.52083935
11MST42.47219237
12CDK192.43653820
13BUB12.42126808
14OXSR12.39056365
15NME12.37992544
16BCKDK2.19579413
17CASK2.17435047
18EIF2AK12.12661122
19PIM21.93541257
20BMPR1B1.92006286
21EIF2AK31.90014642
22VRK11.86712326
23MAPKAPK51.86027558
24BCR1.84983367
25TNIK1.80681906
26NUAK11.80092562
27NEK11.69679565
28FRK1.64597420
29MYLK1.58448373
30LIMK11.55462748
31PINK11.51545466
32BMPR21.48802261
33GRK71.48251532
34MUSK1.47389696
35TRIM281.46797868
36ADRBK21.44436746
37MAP3K41.43748488
38MAP3K51.36969193
39BRAF1.34078625
40TESK21.29919345
41WNK41.20380475
42PDK21.17679901
43GRK51.16734570
44CSNK1G31.14013127
45DYRK21.06243346
46RIPK41.05790020
47TXK1.04517872
48MAP2K71.02303376
49KDR1.01841239
50PLK30.99908053
51IRAK40.98831727
52ABL20.98699496
53BLK0.93294016
54WEE10.89747664
55PNCK0.89729898
56SRPK10.87572001
57PLK40.87446387
58INSRR0.87313725
59PHKG20.86163670
60PHKG10.86163670
61CAMK2B0.84070843
62ERBB30.83990839
63PLK20.81415921
64PRKCG0.81104835
65TLK10.78925506
66MARK10.78439982
67MKNK10.77440580
68TAOK30.75913063
69CAMK2D0.74026787
70TEC0.73082342
71RPS6KA50.72031566
72FGR0.71342819
73PKN10.69339539
74TAF10.68979337
75EIF2AK20.68031702
76TSSK60.66625230
77MAP3K140.65902857
78CDC70.65629179
79DYRK30.65169125
80MINK10.65047879
81ACVR1B0.64558190
82CDK80.63942337
83ZAK0.63857278
84YES10.63443567
85IRAK30.61087090
86CSNK1G10.61077092
87PLK10.59801158
88LYN0.59726123
89PRKCE0.59436868
90MAPK130.59000783
91CAMK2A0.58259378
92FES0.58034162
93CAMK2G0.57861249
94PAK30.57219920
95IKBKB0.56947656
96NEK60.56497383
97GRK10.56176567
98EPHB20.53898941
99SYK0.53277459
100TESK10.53207003
101CSNK1G20.52292081
102CSNK1A1L0.50093451
103WNK30.49786338
104ROCK20.49675751
105SIK30.49621258
106AURKA0.49607488
107MAPKAPK30.49420052
108KIT0.48583001
109ADRBK10.47442452
110CDK140.46914600
111BRSK20.46601083
112UHMK10.46216302
113MAPK150.45296152
114DAPK30.44555417
115CSNK1A10.44405304
116PAK10.43733856
117OBSCN0.43298013
118CSNK2A10.43034474
119AURKB0.42605295
120SIK20.42375196
121MOS0.41507234
122TTK0.41260430
123LCK0.38343313
124CCNB10.38265457
125PRPF4B0.37937653
126DAPK10.37382695
127PRKCD0.36011156
128CDK11A0.35255917
129CDK180.35051751
130PRKCI0.34518690
131PRKCQ0.34063275
132CSNK2A20.34020035
133CLK10.33191279
134EPHA40.32847333
135PRKACA0.32389854
136TIE10.32379438
137ILK0.31930483
138CDK150.31596627
139MKNK20.30702148

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.55673600
2Parkinsons disease_Homo sapiens_hsa050124.61726831
3Proteasome_Homo sapiens_hsa030504.53355350
4Ribosome_Homo sapiens_hsa030103.94460218
5Alzheimers disease_Homo sapiens_hsa050103.48970028
6Protein export_Homo sapiens_hsa030603.47110169
7Huntingtons disease_Homo sapiens_hsa050163.23393632
8RNA polymerase_Homo sapiens_hsa030202.86912185
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.83218977
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.35752021
11Collecting duct acid secretion_Homo sapiens_hsa049662.26262213
12Fatty acid elongation_Homo sapiens_hsa000621.92055382
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74319467
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.65972150
15Cardiac muscle contraction_Homo sapiens_hsa042601.62023882
16Rheumatoid arthritis_Homo sapiens_hsa053231.58532300
17SNARE interactions in vesicular transport_Homo sapiens_hsa041301.53814062
18Pyrimidine metabolism_Homo sapiens_hsa002401.48342009
19Vibrio cholerae infection_Homo sapiens_hsa051101.43999488
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.41307563
21Propanoate metabolism_Homo sapiens_hsa006401.35109687
22Steroid biosynthesis_Homo sapiens_hsa001001.32108295
23Butanoate metabolism_Homo sapiens_hsa006501.31257850
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.17116658
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.16227203
26Ether lipid metabolism_Homo sapiens_hsa005651.14195562
27Allograft rejection_Homo sapiens_hsa053301.12686331
28Sulfur metabolism_Homo sapiens_hsa009201.11763890
29Sulfur relay system_Homo sapiens_hsa041221.09860169
30Graft-versus-host disease_Homo sapiens_hsa053321.08738704
31Homologous recombination_Homo sapiens_hsa034401.06117141
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00713526
33Phagosome_Homo sapiens_hsa041451.00191633
34Autoimmune thyroid disease_Homo sapiens_hsa053200.98204641
35Spliceosome_Homo sapiens_hsa030400.97582104
36Glutathione metabolism_Homo sapiens_hsa004800.93503109
37Basal transcription factors_Homo sapiens_hsa030220.92844595
38DNA replication_Homo sapiens_hsa030300.92457170
39Maturity onset diabetes of the young_Homo sapiens_hsa049500.92391296
40Sphingolipid metabolism_Homo sapiens_hsa006000.92198427
41Purine metabolism_Homo sapiens_hsa002300.92064029
42Arachidonic acid metabolism_Homo sapiens_hsa005900.90979383
43Nucleotide excision repair_Homo sapiens_hsa034200.89131366
44Nitrogen metabolism_Homo sapiens_hsa009100.88092827
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.86361295
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.85034132
47Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.85033793
48Asthma_Homo sapiens_hsa053100.84839434
49Mismatch repair_Homo sapiens_hsa034300.84138257
50Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.84108331
51Chemical carcinogenesis_Homo sapiens_hsa052040.83954971
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.80934756
53Metabolic pathways_Homo sapiens_hsa011000.78878060
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.77560540
55Regulation of autophagy_Homo sapiens_hsa041400.77336534
56Synaptic vesicle cycle_Homo sapiens_hsa047210.76944568
57Primary bile acid biosynthesis_Homo sapiens_hsa001200.76400978
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72766625
59Phototransduction_Homo sapiens_hsa047440.72535965
60Serotonergic synapse_Homo sapiens_hsa047260.72505340
61Pentose and glucuronate interconversions_Homo sapiens_hsa000400.72493664
62One carbon pool by folate_Homo sapiens_hsa006700.70423245
63Selenocompound metabolism_Homo sapiens_hsa004500.68402176
64Folate biosynthesis_Homo sapiens_hsa007900.67922609
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67429012
66Tryptophan metabolism_Homo sapiens_hsa003800.65232292
67Non-homologous end-joining_Homo sapiens_hsa034500.64950123
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63275982
69Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61292430
70RNA degradation_Homo sapiens_hsa030180.61139584
71Type I diabetes mellitus_Homo sapiens_hsa049400.60964243
72Histidine metabolism_Homo sapiens_hsa003400.60702492
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.59318765
74Linoleic acid metabolism_Homo sapiens_hsa005910.58040309
75Caffeine metabolism_Homo sapiens_hsa002320.57812151
76Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.56730694
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.56288491
78Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54409024
79Intestinal immune network for IgA production_Homo sapiens_hsa046720.52928243
80Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52833670
81Pyruvate metabolism_Homo sapiens_hsa006200.51552297
82Nicotine addiction_Homo sapiens_hsa050330.51114862
83Other glycan degradation_Homo sapiens_hsa005110.50494798
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49354130
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48608002
86Retinol metabolism_Homo sapiens_hsa008300.47093722
87African trypanosomiasis_Homo sapiens_hsa051430.44932479
88Malaria_Homo sapiens_hsa051440.44775814
89Base excision repair_Homo sapiens_hsa034100.43340258
90Primary immunodeficiency_Homo sapiens_hsa053400.41724198
91beta-Alanine metabolism_Homo sapiens_hsa004100.41669342
92Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.41668862
93Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.40822051
94Tyrosine metabolism_Homo sapiens_hsa003500.39725362
95Pertussis_Homo sapiens_hsa051330.39624084
96Epstein-Barr virus infection_Homo sapiens_hsa051690.38921114
97Hematopoietic cell lineage_Homo sapiens_hsa046400.38814507
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.38251474
99Carbon metabolism_Homo sapiens_hsa012000.37836634
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37129466
101Arginine and proline metabolism_Homo sapiens_hsa003300.37105789
102Lysosome_Homo sapiens_hsa041420.36862879
103Olfactory transduction_Homo sapiens_hsa047400.36809704
1042-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.35523823
105Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.34857647
106Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.34362001
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.33060610
108Fatty acid metabolism_Homo sapiens_hsa012120.33042572
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32826858
110Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29470147
111Fatty acid degradation_Homo sapiens_hsa000710.29370607
112Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.29303866
113Legionellosis_Homo sapiens_hsa051340.29167739
114Salmonella infection_Homo sapiens_hsa051320.29049671
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28735359
116GABAergic synapse_Homo sapiens_hsa047270.28384380
117NOD-like receptor signaling pathway_Homo sapiens_hsa046210.26818951
118Fanconi anemia pathway_Homo sapiens_hsa034600.26384889
119Peroxisome_Homo sapiens_hsa041460.26248076
120Alcoholism_Homo sapiens_hsa050340.25541087
121Taste transduction_Homo sapiens_hsa047420.24467190
122Phenylalanine metabolism_Homo sapiens_hsa003600.23486859
123RNA transport_Homo sapiens_hsa030130.23473598
124Fat digestion and absorption_Homo sapiens_hsa049750.23010782
125Morphine addiction_Homo sapiens_hsa050320.22128238
126Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.21527518
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.20831985
128Vitamin B6 metabolism_Homo sapiens_hsa007500.20537893
129Circadian rhythm_Homo sapiens_hsa047100.20308864
130Shigellosis_Homo sapiens_hsa051310.20292105
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18681490
132Pentose phosphate pathway_Homo sapiens_hsa000300.17198423
133Systemic lupus erythematosus_Homo sapiens_hsa053220.16906346
134Oocyte meiosis_Homo sapiens_hsa041140.16904999
135Tuberculosis_Homo sapiens_hsa051520.16668442
136Mineral absorption_Homo sapiens_hsa049780.15789113

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