LANCL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.65618776
2synaptic vesicle maturation (GO:0016188)5.54685069
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.51925939
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.30802879
5glutamate secretion (GO:0014047)5.28459888
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.11444191
7vocalization behavior (GO:0071625)5.09793654
8positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr5.07625192
9ovulation cycle (GO:0042698)4.94889619
10locomotory exploration behavior (GO:0035641)4.94668174
11cilium or flagellum-dependent cell motility (GO:0001539)4.91662444
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.88940674
13regulation of synaptic vesicle exocytosis (GO:2000300)4.88732290
14positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.87832199
15pyrimidine nucleobase catabolic process (GO:0006208)4.86531776
16protein localization to synapse (GO:0035418)4.85842988
17protein insertion into membrane (GO:0051205)4.83444284
18tongue development (GO:0043586)4.82865487
19neuron cell-cell adhesion (GO:0007158)4.62487912
20regulation of glutamate receptor signaling pathway (GO:1900449)4.59083137
21regulation of phospholipase A2 activity (GO:0032429)4.49204131
22layer formation in cerebral cortex (GO:0021819)4.41085428
23exploration behavior (GO:0035640)4.39250873
24positive regulation of vascular permeability (GO:0043117)4.36065593
25regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 4.28983299
26regulation of synaptic vesicle transport (GO:1902803)4.23313891
27regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.22542816
28establishment of mitochondrion localization (GO:0051654)4.21745500
29neurotransmitter secretion (GO:0007269)4.19978828
30positive regulation of synaptic transmission, glutamatergic (GO:0051968)4.11791954
31sperm motility (GO:0030317)4.04089372
32ionotropic glutamate receptor signaling pathway (GO:0035235)4.01486162
33positive regulation of synapse maturation (GO:0090129)4.00642060
34acrosome assembly (GO:0001675)3.91920047
35coronary vasculature morphogenesis (GO:0060977)3.85996672
36regulation of long-term neuronal synaptic plasticity (GO:0048169)3.85557304
37glutamate receptor signaling pathway (GO:0007215)3.84339587
38calcium ion-dependent exocytosis (GO:0017156)3.80582380
39nucleobase catabolic process (GO:0046113)3.79428808
40negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.74593611
41regulation of neuronal synaptic plasticity (GO:0048168)3.69721282
42regulation of synapse structural plasticity (GO:0051823)3.67322752
43synaptic transmission, glutamatergic (GO:0035249)3.62589981
44proline transport (GO:0015824)3.62391222
45glucosamine-containing compound catabolic process (GO:1901072)3.60534245
46acrosome reaction (GO:0007340)3.57249616
47gamma-aminobutyric acid signaling pathway (GO:0007214)3.55076407
48neuron recognition (GO:0008038)3.53636950
49neuron-neuron synaptic transmission (GO:0007270)3.53261573
50neurotransmitter-gated ion channel clustering (GO:0072578)3.52222499
51epithelial cilium movement (GO:0003351)3.50898980
52positive regulation of catenin import into nucleus (GO:0035413)3.47961774
53synapse assembly (GO:0007416)3.47949424
54dendritic spine morphogenesis (GO:0060997)3.47303738
55regulation of axon extension involved in axon guidance (GO:0048841)3.43909080
56synaptic vesicle endocytosis (GO:0048488)3.42818499
57neuronal action potential propagation (GO:0019227)3.36916007
58regulation of excitatory postsynaptic membrane potential (GO:0060079)3.35085489
59postsynaptic membrane organization (GO:0001941)3.34612581
60neurotransmitter transport (GO:0006836)3.33651516
61response to phenylpropanoid (GO:0080184)3.33460743
62axonal fasciculation (GO:0007413)3.32621263
63regulation of axon guidance (GO:1902667)3.32049879
64axonemal dynein complex assembly (GO:0070286)3.28793952
65fusion of sperm to egg plasma membrane (GO:0007342)3.26909416
66regulation of neurotransmitter secretion (GO:0046928)3.26849240
67positive regulation of p38MAPK cascade (GO:1900745)3.26187922
68positive regulation of membrane potential (GO:0045838)3.24560182
69presynaptic membrane assembly (GO:0097105)3.24379816
70long-term synaptic potentiation (GO:0060291)3.23128100
71regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.22622106
72regulation of postsynaptic membrane potential (GO:0060078)3.22536654
73vesicle transport along microtubule (GO:0047496)3.21950684
74establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.21032448
75mitochondrion transport along microtubule (GO:0047497)3.21032448
76cilium movement (GO:0003341)3.18450089
77epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.17032476
78neuronal ion channel clustering (GO:0045161)3.16824736
79regulation of synaptic plasticity (GO:0048167)3.16456599
80cellular potassium ion homeostasis (GO:0030007)3.15987349
81membrane depolarization during action potential (GO:0086010)3.15753046
82response to histamine (GO:0034776)3.14881018
83sperm-egg recognition (GO:0035036)3.14413002
84innervation (GO:0060384)3.14174128
85response to pheromone (GO:0019236)3.13973340
86cerebral cortex cell migration (GO:0021795)3.13613337
87positive regulation of neurotransmitter secretion (GO:0001956)3.12694610
88regulation of dendritic spine morphogenesis (GO:0061001)3.10442471
89piRNA metabolic process (GO:0034587)3.10385560
90positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.09946470
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.08326730
92negative regulation of microtubule polymerization (GO:0031115)3.08168230
93protein localization to cilium (GO:0061512)3.07746483
94amino acid import (GO:0043090)3.07656649
95negative regulation of synaptic transmission, GABAergic (GO:0032229)3.07448507
96long-term memory (GO:0007616)3.05712053
97gamma-aminobutyric acid transport (GO:0015812)3.05437628
98clathrin coat assembly (GO:0048268)3.04203701
99regulation of synaptic transmission, glutamatergic (GO:0051966)3.03679106
100activation of protein kinase A activity (GO:0034199)3.03297301
101plasma membrane fusion (GO:0045026)3.02380158
102organelle transport along microtubule (GO:0072384)3.01905077
103positive regulation of dendritic spine morphogenesis (GO:0061003)2.99111179
104auditory behavior (GO:0031223)2.98593450
105dendrite morphogenesis (GO:0048813)2.98131141
106lung vasculature development (GO:0060426)2.98028611
107regulation of neurotransmitter levels (GO:0001505)2.97931070
108cerebellar Purkinje cell differentiation (GO:0021702)2.97583304
109binding of sperm to zona pellucida (GO:0007339)2.97238019
110presynaptic membrane organization (GO:0097090)2.96002874
111sodium ion export (GO:0071436)2.95907544
112regulation of cilium movement (GO:0003352)2.94729943
113regulation of neurotransmitter transport (GO:0051588)2.93664282
114negative regulation of organelle assembly (GO:1902116)2.92953192
115hippocampus development (GO:0021766)2.92801679
116regulation of vesicle fusion (GO:0031338)2.92554135
117intraspecies interaction between organisms (GO:0051703)2.91854920
118social behavior (GO:0035176)2.91854920
119membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.91627616
120central nervous system projection neuron axonogenesis (GO:0021952)2.91560960
121positive regulation of neurotransmitter transport (GO:0051590)2.91465947
122negative regulation of inclusion body assembly (GO:0090084)2.88607451
123positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737)2.88526813
124regulation of superoxide anion generation (GO:0032928)2.88523304
125cerebellar granule cell differentiation (GO:0021707)2.87980956
126membrane depolarization (GO:0051899)2.87748669
127cell migration in hindbrain (GO:0021535)2.87115040
128behavioral defense response (GO:0002209)2.86590492
129behavioral fear response (GO:0001662)2.86590492
130positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.85701128
131L-amino acid import (GO:0043092)2.84835587
132ventricular system development (GO:0021591)2.82992225
133regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.80753265
134response to auditory stimulus (GO:0010996)2.80211788
135transmission of nerve impulse (GO:0019226)2.78626739
136cerebral cortex neuron differentiation (GO:0021895)2.75258425
137mechanosensory behavior (GO:0007638)2.73910834
138acidic amino acid transport (GO:0015800)2.72741102
139dendritic spine organization (GO:0097061)2.71349477
140positive regulation of synapse assembly (GO:0051965)2.70823164
141camera-type eye morphogenesis (GO:0048593)2.69548281
142calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.69153983
143neuromuscular synaptic transmission (GO:0007274)2.67381025
144synapse organization (GO:0050808)2.66816575
145positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949)2.62675050
146digestive tract morphogenesis (GO:0048546)2.61934884
147regulation of endothelial cell chemotaxis (GO:2001026)2.61294070
148membrane assembly (GO:0071709)2.60408546
149positive regulation of dendritic spine development (GO:0060999)2.57809719
150axon cargo transport (GO:0008088)2.56305709
151axon extension (GO:0048675)2.53793277

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.78788927
2GBX2_23144817_ChIP-Seq_PC3_Human3.36120500
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.97581597
4REST_21632747_ChIP-Seq_MESCs_Mouse2.91111898
5NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.65059389
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.60395737
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.58191174
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.53420045
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.44427501
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.33010106
11RARB_27405468_Chip-Seq_BRAIN_Mouse2.27263290
12ZNF274_21170338_ChIP-Seq_K562_Hela2.26135028
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.26038919
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.20763363
15TAF15_26573619_Chip-Seq_HEK293_Human2.20319802
16REST_18959480_ChIP-ChIP_MESCs_Mouse2.19602699
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.16071929
18RBPJ_22232070_ChIP-Seq_NCS_Mouse2.11093179
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.08108616
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.05157122
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.01599698
22EZH2_27304074_Chip-Seq_ESCs_Mouse2.00872543
23BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.00120442
24ESR1_15608294_ChIP-ChIP_MCF-7_Human1.97059062
25MTF2_20144788_ChIP-Seq_MESCs_Mouse1.95419279
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.92544750
27SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.89821335
28DROSHA_22980978_ChIP-Seq_HELA_Human1.86577899
29FUS_26573619_Chip-Seq_HEK293_Human1.85554160
30RNF2_18974828_ChIP-Seq_MESCs_Mouse1.84308489
31EZH2_18974828_ChIP-Seq_MESCs_Mouse1.84308489
32SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.83879672
33SUZ12_27294783_Chip-Seq_ESCs_Mouse1.83619058
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.83417958
35BP1_19119308_ChIP-ChIP_Hs578T_Human1.81857880
36SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.80794855
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.80684643
38SMAD4_21799915_ChIP-Seq_A2780_Human1.80099569
39RNF2_27304074_Chip-Seq_ESCs_Mouse1.75850237
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.74847948
41IGF1R_20145208_ChIP-Seq_DFB_Human1.71283426
42SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.69387444
43CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.60038934
44PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.59585765
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.54268992
46P300_19829295_ChIP-Seq_ESCs_Human1.53564803
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.52598106
48EED_16625203_ChIP-ChIP_MESCs_Mouse1.51390344
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.49535054
50GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48657457
51CBX2_27304074_Chip-Seq_ESCs_Mouse1.48251577
52MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.48181577
53RNF2_27304074_Chip-Seq_NSC_Mouse1.44942963
54NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.40815976
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.40292443
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.38341261
57PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38026002
58EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.36866250
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35029366
60AR_21572438_ChIP-Seq_LNCaP_Human1.34330620
61AR_25329375_ChIP-Seq_VCAP_Human1.34108405
62IKZF1_21737484_ChIP-ChIP_HCT116_Human1.32750900
63RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.31216280
64PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30078508
65TCF4_23295773_ChIP-Seq_U87_Human1.28954100
66* SOX2_21211035_ChIP-Seq_LN229_Gbm1.28305802
67STAT3_23295773_ChIP-Seq_U87_Human1.27230029
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.26891571
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25575029
70HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.24665863
71SOX9_26525672_Chip-Seq_HEART_Mouse1.24616587
72ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24116078
73JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.23092483
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22899209
75REST_19997604_ChIP-ChIP_NEURONS_Mouse1.22018547
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21476646
77SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21446608
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.20833955
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.19901057
80ETS1_20019798_ChIP-Seq_JURKAT_Human1.19550344
81MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.19201607
82* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.17625990
83TRIM28_21343339_ChIP-Seq_HEK293_Human1.17508906
84VDR_22108803_ChIP-Seq_LS180_Human1.17405624
85CBP_20019798_ChIP-Seq_JUKART_Human1.17104803
86IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17104803
87* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14285551
88TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13660174
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13660174
90KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.12450424
91* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12141598
92CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11414855
93* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.11388469
94ER_23166858_ChIP-Seq_MCF-7_Human1.10430125
95TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09375504
96SMAD3_21741376_ChIP-Seq_ESCs_Human1.09304396
97TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.09240981
98ZFP281_18757296_ChIP-ChIP_E14_Mouse1.08711804
99OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.08557492
100RING1B_27294783_Chip-Seq_ESCs_Mouse1.08182939
101TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.06867692
102P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05812264
103* AR_19668381_ChIP-Seq_PC3_Human1.05641741
104FLI1_21867929_ChIP-Seq_TH2_Mouse1.05570595
105MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04840964
106KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03959023
107SALL1_21062744_ChIP-ChIP_HESCs_Human1.03606074
108BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03560930
109* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03056480
110RUNX1_26923725_Chip-Seq_HPCs_Mouse1.02986379
111SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02735072
112PIAS1_25552417_ChIP-Seq_VCAP_Human1.02615869
113RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.02606464
114YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02499129
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02377446
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01222958
117JUN_21703547_ChIP-Seq_K562_Human1.00947526
118YY1_21170310_ChIP-Seq_MESCs_Mouse1.00148154
119KDM2B_26808549_Chip-Seq_REH_Human0.98413685
120RUNX2_22187159_ChIP-Seq_PCA_Human0.98193796
121CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97974557
122* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97104112
123CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.96986683
124NANOG_18555785_Chip-Seq_ESCs_Mouse0.95902699
125TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.95504493
126MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94769219
127GATA1_26923725_Chip-Seq_HPCs_Mouse0.94182108
128TET1_21490601_ChIP-Seq_MESCs_Mouse0.94152844
129ARNT_22903824_ChIP-Seq_MCF-7_Human0.93311449
130NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91875962
131* PRDM14_20953172_ChIP-Seq_ESCs_Human0.91426950
132HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.91365773
133CREB1_15753290_ChIP-ChIP_HEK293T_Human0.91168164
134WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.91068778
135TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.89711214
136EWS_26573619_Chip-Seq_HEK293_Human0.88705839
137GABP_19822575_ChIP-Seq_HepG2_Human0.88080507
138THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87744358
139DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85596397
140CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.84157150
141PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83753677
142* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83387484
143ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.83165333

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation7.31219439
2MP0004859_abnormal_synaptic_plasticity6.02610398
3MP0003880_abnormal_central_pattern4.26190407
4MP0003635_abnormal_synaptic_transmissio3.95179765
5MP0004270_analgesia3.69236943
6MP0005410_abnormal_fertilization3.58711817
7MP0002063_abnormal_learning/memory/cond3.24631882
8MP0009046_muscle_twitch3.06080465
9MP0009745_abnormal_behavioral_response3.03105446
10MP0001968_abnormal_touch/_nociception2.93997032
11MP0002064_seizures2.79164765
12MP0000579_abnormal_nail_morphology2.68065342
13MP0002572_abnormal_emotion/affect_behav2.63358203
14MP0009384_cardiac_valve_regurgitation2.57356897
15MP0002734_abnormal_mechanical_nocicepti2.54223120
16MP0005423_abnormal_somatic_nervous2.50279377
17MP0008877_abnormal_DNA_methylation2.27571171
18MP0002736_abnormal_nociception_after2.26175488
19MP0002272_abnormal_nervous_system2.21582043
20MP0001984_abnormal_olfaction2.09941862
21MP0001486_abnormal_startle_reflex2.08264338
22MP0000778_abnormal_nervous_system2.01890370
23MP0004811_abnormal_neuron_physiology1.98996266
24MP0002735_abnormal_chemical_nociception1.96468819
25MP0000569_abnormal_digit_pigmentation1.94678283
26MP0009780_abnormal_chondrocyte_physiolo1.93334158
27MP0001440_abnormal_grooming_behavior1.93293699
28MP0002733_abnormal_thermal_nociception1.86598634
29MP0002184_abnormal_innervation1.86597374
30MP0002067_abnormal_sensory_capabilities1.86329514
31MP0001177_atelectasis1.83475920
32MP0001501_abnormal_sleep_pattern1.82550894
33MP0003698_abnormal_male_reproductive1.76182316
34MP0003787_abnormal_imprinting1.73327796
35MP0006276_abnormal_autonomic_nervous1.71366519
36MP0008569_lethality_at_weaning1.70727133
37MP0002557_abnormal_social/conspecific_i1.69868711
38MP0001970_abnormal_pain_threshold1.68102761
39MP0003329_amyloid_beta_deposits1.65536286
40MP0004924_abnormal_behavior1.65123410
41MP0005386_behavior/neurological_phenoty1.65123410
42MP0008775_abnormal_heart_ventricle1.64520356
43MP0003122_maternal_imprinting1.57510088
44MP0005646_abnormal_pituitary_gland1.55797934
45MP0000955_abnormal_spinal_cord1.51570820
46MP0002822_catalepsy1.45589248
47MP0000383_abnormal_hair_follicle1.45037673
48MP0002882_abnormal_neuron_morphology1.44903694
49MP0004858_abnormal_nervous_system1.42847939
50MP0004233_abnormal_muscle_weight1.36993412
51MP0002909_abnormal_adrenal_gland1.34660767
52MP0002152_abnormal_brain_morphology1.32019680
53MP0002066_abnormal_motor_capabilities/c1.30059178
54MP0001929_abnormal_gametogenesis1.29027060
55MP0003879_abnormal_hair_cell1.27179699
56MP0001502_abnormal_circadian_rhythm1.23731750
57MP0001529_abnormal_vocalization1.22994675
58MP0000747_muscle_weakness1.20179101
59MP0005551_abnormal_eye_electrophysiolog1.19726566
60MP0000427_abnormal_hair_cycle1.18024805
61MP0003633_abnormal_nervous_system1.16815951
62MP0005187_abnormal_penis_morphology1.10006740
63MP0005645_abnormal_hypothalamus_physiol1.09726874
64MP0003631_nervous_system_phenotype1.06605469
65MP0001905_abnormal_dopamine_level1.06312482
66MP0002095_abnormal_skin_pigmentation1.06097043
67MP0000631_abnormal_neuroendocrine_gland1.05340336
68MP0000467_abnormal_esophagus_morphology1.03563009
69MP0002161_abnormal_fertility/fecundity0.99659160
70MP0002653_abnormal_ependyma_morphology0.98528890
71MP0001188_hyperpigmentation0.94804941
72MP0003137_abnormal_impulse_conducting0.93349002
73MP0010678_abnormal_skin_adnexa0.93316038
74MP0003861_abnormal_nervous_system0.93001164
75MP0003121_genomic_imprinting0.92096400
76MP0003646_muscle_fatigue0.91508112
77MP0004142_abnormal_muscle_tone0.90234099
78MP0004885_abnormal_endolymph0.89704733
79MP0005499_abnormal_olfactory_system0.89118014
80MP0005394_taste/olfaction_phenotype0.89118014
81MP0002229_neurodegeneration0.88393788
82MP0000751_myopathy0.87715399
83MP0000678_abnormal_parathyroid_gland0.87188860
84MP0002234_abnormal_pharynx_morphology0.85970174
85MP0002177_abnormal_outer_ear0.85201590
86MP0003690_abnormal_glial_cell0.82259129
87MP0002638_abnormal_pupillary_reflex0.82048760
88MP0003136_yellow_coat_color0.81080759
89MP0005623_abnormal_meninges_morphology0.78995258
90MP0002210_abnormal_sex_determination0.78935148
91MP0002752_abnormal_somatic_nervous0.78850706
92MP0004145_abnormal_muscle_electrophysio0.78364270
93MP0006072_abnormal_retinal_apoptosis0.78282362
94MP0000762_abnormal_tongue_morphology0.78010852
95MP0010386_abnormal_urinary_bladder0.76656189
96MP0003755_abnormal_palate_morphology0.76645446
97MP0000049_abnormal_middle_ear0.76399131
98MP0002837_dystrophic_cardiac_calcinosis0.75926731
99MP0003115_abnormal_respiratory_system0.75719605
100MP0002069_abnormal_eating/drinking_beha0.74573927
101MP0003632_abnormal_nervous_system0.74458450
102MP0008789_abnormal_olfactory_epithelium0.73009621
103MP0002090_abnormal_vision0.71282446
104MP0008872_abnormal_physiological_respon0.71070754
105MP0004215_abnormal_myocardial_fiber0.70011397
106MP0003634_abnormal_glial_cell0.69332529
107MP0001145_abnormal_male_reproductive0.68646814
108MP0003123_paternal_imprinting0.68305664
109MP0001879_abnormal_lymphatic_vessel0.68072511
110MP0000920_abnormal_myelination0.67599924
111MP0004085_abnormal_heartbeat0.67486072
112MP0000604_amyloidosis0.67390613
113MP0002098_abnormal_vibrissa_morphology0.67211034
114MP0001963_abnormal_hearing_physiology0.64568674
115MP0005391_vision/eye_phenotype0.63391391
116MP0005253_abnormal_eye_physiology0.63204635
117MP0002697_abnormal_eye_size0.62710221
118MP0001986_abnormal_taste_sensitivity0.62050615
119MP0000653_abnormal_sex_gland0.61840076
120MP0002102_abnormal_ear_morphology0.61723926
121MP0002081_perinatal_lethality0.59896811
122MP0008260_abnormal_autophagy0.59760619
123MP0000613_abnormal_salivary_gland0.59445231
124MP0010769_abnormal_survival0.59041708
125MP0001299_abnormal_eye_distance/0.58902826
126MP0010770_preweaning_lethality0.58137777
127MP0002082_postnatal_lethality0.58137777
128MP0003890_abnormal_embryonic-extraembry0.58053262
129MP0001943_abnormal_respiration0.57886977
130MP0008961_abnormal_basal_metabolism0.57748552

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.51854689
2Absent/shortened dynein arms (HP:0200106)5.23545485
3Dynein arm defect of respiratory motile cilia (HP:0012255)5.23545485
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.82386038
5Myokymia (HP:0002411)4.72272419
6Epileptic encephalopathy (HP:0200134)4.71156757
7Focal seizures (HP:0007359)4.50980151
8Visual hallucinations (HP:0002367)4.47810110
9Progressive cerebellar ataxia (HP:0002073)3.81562440
10Atonic seizures (HP:0010819)3.71217319
11Abnormal respiratory epithelium morphology (HP:0012253)3.66960641
12Abnormal respiratory motile cilium morphology (HP:0005938)3.66960641
13Abnormal respiratory motile cilium physiology (HP:0012261)3.60388867
14Cortical dysplasia (HP:0002539)3.57039273
15Hyperventilation (HP:0002883)3.56278029
16Split foot (HP:0001839)3.53888243
17Absence seizures (HP:0002121)3.53758971
18Abnormality of the lower motor neuron (HP:0002366)3.43201112
19Febrile seizures (HP:0002373)3.41106022
20Papilledema (HP:0001085)3.37546604
21Amyotrophic lateral sclerosis (HP:0007354)3.26417498
22Dialeptic seizures (HP:0011146)3.12347612
23Rhinitis (HP:0012384)3.06449869
24Broad-based gait (HP:0002136)3.03864870
25Impaired vibration sensation in the lower limbs (HP:0002166)3.00405760
26Gaze-evoked nystagmus (HP:0000640)2.99398767
27Abnormal ciliary motility (HP:0012262)2.94003438
28Supranuclear gaze palsy (HP:0000605)2.90497807
29Generalized tonic-clonic seizures (HP:0002069)2.86556589
30Overriding aorta (HP:0002623)2.78952929
31Action tremor (HP:0002345)2.75615677
32Poor eye contact (HP:0000817)2.73920092
33Infertility (HP:0000789)2.73711893
34Truncal ataxia (HP:0002078)2.72807038
35Depression (HP:0000716)2.71728557
36Mutism (HP:0002300)2.65909641
37Urinary bladder sphincter dysfunction (HP:0002839)2.64542600
38Chronic bronchitis (HP:0004469)2.63910495
39Sleep apnea (HP:0010535)2.63071967
40Excessive salivation (HP:0003781)2.61791261
41Drooling (HP:0002307)2.61791261
42Gait imbalance (HP:0002141)2.57110677
43Absent speech (HP:0001344)2.55466239
44Impaired smooth pursuit (HP:0007772)2.55053261
45Ankle clonus (HP:0011448)2.54586225
46Abnormality of ocular smooth pursuit (HP:0000617)2.51188112
47Alveolar cell carcinoma (HP:0006519)2.51139169
48Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.50986122
49Degeneration of the lateral corticospinal tracts (HP:0002314)2.50986122
50Cerebral hypomyelination (HP:0006808)2.49643697
51Retinal dysplasia (HP:0007973)2.48641336
52Progressive inability to walk (HP:0002505)2.48392214
53Termporal pattern (HP:0011008)2.48050850
54Insidious onset (HP:0003587)2.48050850
55Postural instability (HP:0002172)2.43313669
56Fetal akinesia sequence (HP:0001989)2.42438087
57Dysdiadochokinesis (HP:0002075)2.41048070
58Genetic anticipation (HP:0003743)2.39642745
59Abnormal social behavior (HP:0012433)2.39066852
60Impaired social interactions (HP:0000735)2.39066852
61Hemiparesis (HP:0001269)2.37470649
62Urinary urgency (HP:0000012)2.36012305
63Spastic tetraplegia (HP:0002510)2.35532257
64Abnormal eating behavior (HP:0100738)2.34272361
65Inability to walk (HP:0002540)2.33496146
66Amblyopia (HP:0000646)2.31684587
67Epileptiform EEG discharges (HP:0011182)2.31053715
68Poor suck (HP:0002033)2.29250483
69Neoplasm of the tracheobronchial system (HP:0100552)2.27860076
70Polyphagia (HP:0002591)2.24125297
71Inappropriate behavior (HP:0000719)2.23791745
72Lissencephaly (HP:0001339)2.22908519
73Limb dystonia (HP:0002451)2.21973194
74EEG with generalized epileptiform discharges (HP:0011198)2.20049210
75Medial flaring of the eyebrow (HP:0010747)2.19922382
76Abnormality of the corticospinal tract (HP:0002492)2.18202492
77Diplopia (HP:0000651)2.16692099
78Abnormality of binocular vision (HP:0011514)2.16692099
79Atrophy/Degeneration involving motor neurons (HP:0007373)2.16484261
80Cerebral inclusion bodies (HP:0100314)2.14992306
81Peripheral hypomyelination (HP:0007182)2.13692648
82Dysmetric saccades (HP:0000641)2.12879695
83Failure to thrive in infancy (HP:0001531)2.12065046
84Anxiety (HP:0000739)2.12045098
85Aplasia/Hypoplasia of the brainstem (HP:0007362)2.11449106
86Hypoplasia of the brainstem (HP:0002365)2.11449106
87Hypsarrhythmia (HP:0002521)2.10236521
88Intention tremor (HP:0002080)2.09731986
89Hyperacusis (HP:0010780)2.09497854
90Elfin facies (HP:0004428)2.08193106
91Impaired vibratory sensation (HP:0002495)2.06800354
92Obstructive sleep apnea (HP:0002870)2.06405168
93Shoulder girdle muscle weakness (HP:0003547)2.06349542
94Congenital primary aphakia (HP:0007707)2.06306347
95Bradykinesia (HP:0002067)2.05892162
96Spastic gait (HP:0002064)2.05484648
97Dysmetria (HP:0001310)2.05360225
98Morphological abnormality of the pyramidal tract (HP:0002062)2.03669081
99Specific learning disability (HP:0001328)2.00676077
100Nephronophthisis (HP:0000090)1.98205463
101Broad distal phalanx of finger (HP:0009836)1.98117359
102Stereotypic behavior (HP:0000733)1.96723352
103Hypoplasia of the corpus callosum (HP:0002079)1.92872178
104Akinesia (HP:0002304)1.91567595
105CNS hypomyelination (HP:0003429)1.91418579
106Pheochromocytoma (HP:0002666)1.91254160
107Intellectual disability, profound (HP:0002187)1.88663664
108Megalencephaly (HP:0001355)1.87192369
109Abnormality of the labia minora (HP:0012880)1.85242970
110Nephrogenic diabetes insipidus (HP:0009806)1.84778362
111Protruding tongue (HP:0010808)1.84416877
112Spastic tetraparesis (HP:0001285)1.83614725
113Medulloblastoma (HP:0002885)1.82218663
114Lower limb muscle weakness (HP:0007340)1.80822011
115Renovascular hypertension (HP:0100817)1.80303831
116Widely spaced teeth (HP:0000687)1.79631380
117Pointed chin (HP:0000307)1.79421947
118Neurofibrillary tangles (HP:0002185)1.79269006
119Insomnia (HP:0100785)1.78046521
120Neuroendocrine neoplasm (HP:0100634)1.77046135
121Astrocytoma (HP:0009592)1.76684631
122Abnormality of the astrocytes (HP:0100707)1.76684631
123Pachygyria (HP:0001302)1.76492613
124Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.76105052
125Agitation (HP:0000713)1.73899767
126Turricephaly (HP:0000262)1.73300927
127Central scotoma (HP:0000603)1.72676544
128Torticollis (HP:0000473)1.71541629
129Gait ataxia (HP:0002066)1.71041261
130Esotropia (HP:0000565)1.70889787
131Hand muscle atrophy (HP:0009130)1.70292156
132Abnormality of midbrain morphology (HP:0002418)1.69976358
133Molar tooth sign on MRI (HP:0002419)1.69976358
134Tubulointerstitial nephritis (HP:0001970)1.69890110
135Aqueductal stenosis (HP:0002410)1.69592531
136Decreased muscle mass (HP:0003199)1.68718292
137Papillary thyroid carcinoma (HP:0002895)1.68687857
138Progressive macrocephaly (HP:0004481)1.68356386
139Megalocornea (HP:0000485)1.66089702
140Abnormality of the diencephalon (HP:0010662)1.65649849
141Agnosia (HP:0010524)1.64887348
142Type II lissencephaly (HP:0007260)1.63370255

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB46.94371096
2MARK13.93732884
3NTRK33.60537158
4MAP3K43.49825887
5EPHA43.21742105
6PDK33.13139333
7PDK43.13139333
8PKN13.05149736
9MAP3K93.01957623
10MAP2K72.91398625
11MINK12.70002688
12PNCK2.36765884
13PRKD32.27239870
14CCNB12.21095015
15CASK2.15192041
16DAPK22.12712833
17STK162.09381242
18KSR12.06106115
19MUSK2.01063666
20DAPK11.95089786
21PLK21.93080472
22MAP3K121.90866425
23PAK61.88234813
24MAP2K41.81428772
25CDK191.80366065
26BCR1.79274447
27NTRK21.72832825
28CAMK2G1.71052787
29PDK21.67098255
30ERBB21.62741527
31MAPK111.62689087
32CSNK1A1L1.60940960
33CAMKK11.58696135
34KSR21.52848590
35RIPK41.45972204
36TRIM281.45971718
37CSNK1G11.44546665
38TESK11.38663581
39LIMK11.36392528
40MAPK131.35182323
41PTK2B1.33586244
42CDK51.28003654
43SCYL21.18449035
44PRKCG1.17330851
45UHMK11.09994726
46CDK181.01421989
47CAMKK21.01308501
48CDC71.00417213
49SIK20.99394913
50NEK10.97495310
51PIM20.97254438
52CDK140.97093199
53STK380.96686600
54CDK150.96307731
55NTRK10.95888255
56ICK0.94937912
57GRK50.90468212
58LATS20.88321811
59PHKG10.85933551
60PHKG20.85933551
61CSNK1G20.83518846
62CDK11A0.82746239
63ERBB30.81078493
64CAMK1G0.79843010
65BRSK10.79546438
66TNIK0.79046804
67PRPF4B0.76756804
68CAMK2A0.75637236
69MAP3K60.73488328
70EIF2AK10.73286411
71DYRK1B0.72024790
72RAF10.71539792
73STK110.71461745
74MAP3K20.70685941
75RET0.69156692
76DYRK30.69148623
77CAMK10.67710165
78PDK10.65094176
79PLK30.62861272
80DYRK1A0.61875586
81TAOK10.61135870
82TYRO30.59765644
83ARAF0.58642096
84CAMK2D0.57305139
85SGK2230.55971616
86SGK4940.55971616
87FES0.55610473
88WNK30.50650795
89PAK30.49527708
90SGK10.49302645
91ABL20.48813166
92SGK20.48686192
93SRPK10.48609796
94DYRK20.47120263
95CAMK2B0.45744087
96FGFR20.45238647
97EPHA30.44837098
98ALK0.44400252
99PBK0.44250135
100STK390.43337277
101JAK20.42494360
102CSNK1E0.41752578
103PRKCZ0.41735922
104CSNK1D0.40427509
105SIK30.39784043
106RPS6KA20.39559367
107RPS6KA30.39084936
108BMPR1B0.37674467
109SGK30.37401289
110NEK60.36733502
111MARK20.35261193
112PRKDC0.34472733
113BRAF0.34204785
114OXSR10.33628662
115MAPK100.33475336
116AURKA0.32819382
117ROCK20.32670395
118TSSK60.32459990
119RPS6KB10.32141587
120CSNK1G30.29876364
121RPS6KA40.29662310
122PRKCE0.29469407
123PRKCB0.29063246
124EGFR0.28892901
125PLK10.28870818
126BMPR20.28142507
127PRKCH0.27778654
128MAP3K50.26856086
129PDPK10.26352353
130PTK20.25713503
131LMTK20.25666769
132FYN0.25026591
133DAPK30.24832639
134CSNK1A10.23581409
135DMPK0.23385819
136PINK10.22403695

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.76439017
2Synaptic vesicle cycle_Homo sapiens_hsa047213.61492243
3Long-term potentiation_Homo sapiens_hsa047202.81550065
4Olfactory transduction_Homo sapiens_hsa047402.68900905
5Circadian entrainment_Homo sapiens_hsa047132.68266364
6Amphetamine addiction_Homo sapiens_hsa050312.64908167
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.57574080
8GABAergic synapse_Homo sapiens_hsa047272.48026671
9Morphine addiction_Homo sapiens_hsa050322.36362593
10Glutamatergic synapse_Homo sapiens_hsa047242.35530643
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.31525151
12Dopaminergic synapse_Homo sapiens_hsa047282.25245457
13Salivary secretion_Homo sapiens_hsa049701.94600367
14Insulin secretion_Homo sapiens_hsa049111.91555976
15Renin secretion_Homo sapiens_hsa049241.86523989
16Bladder cancer_Homo sapiens_hsa052191.81763021
17Protein export_Homo sapiens_hsa030601.76713940
18Cholinergic synapse_Homo sapiens_hsa047251.76670198
19Collecting duct acid secretion_Homo sapiens_hsa049661.72768762
20Oocyte meiosis_Homo sapiens_hsa041141.72288462
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.65188925
22Gastric acid secretion_Homo sapiens_hsa049711.64488290
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.63684619
24Oxytocin signaling pathway_Homo sapiens_hsa049211.62329623
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58921008
26Taste transduction_Homo sapiens_hsa047421.55724277
27Long-term depression_Homo sapiens_hsa047301.54043653
28Serotonergic synapse_Homo sapiens_hsa047261.51748713
29Cocaine addiction_Homo sapiens_hsa050301.44927071
30Calcium signaling pathway_Homo sapiens_hsa040201.44482974
31Gap junction_Homo sapiens_hsa045401.36868312
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.31017418
33Estrogen signaling pathway_Homo sapiens_hsa049151.26820981
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25725256
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.24692929
36GnRH signaling pathway_Homo sapiens_hsa049121.19646062
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17863453
38Glioma_Homo sapiens_hsa052141.17478068
39Phototransduction_Homo sapiens_hsa047441.16649194
40Alcoholism_Homo sapiens_hsa050341.13955222
41Oxidative phosphorylation_Homo sapiens_hsa001901.12830482
42Vibrio cholerae infection_Homo sapiens_hsa051101.12510433
43cAMP signaling pathway_Homo sapiens_hsa040241.12396841
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11334094
45Axon guidance_Homo sapiens_hsa043601.10246442
46Type II diabetes mellitus_Homo sapiens_hsa049301.10132053
47Parkinsons disease_Homo sapiens_hsa050121.10113396
48Glucagon signaling pathway_Homo sapiens_hsa049221.09732719
49Dorso-ventral axis formation_Homo sapiens_hsa043201.08244746
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.04507389
51Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.03979700
52Pancreatic cancer_Homo sapiens_hsa052121.01604264
53Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.98480756
54Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.98308519
55Melanoma_Homo sapiens_hsa052180.98218820
56Melanogenesis_Homo sapiens_hsa049160.96482251
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.96385133
58ErbB signaling pathway_Homo sapiens_hsa040120.96167163
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.95323526
60Cardiac muscle contraction_Homo sapiens_hsa042600.93137340
61Basal transcription factors_Homo sapiens_hsa030220.89705600
62Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.88820325
63Regulation of autophagy_Homo sapiens_hsa041400.88147849
64Vitamin B6 metabolism_Homo sapiens_hsa007500.85007285
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81590915
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81133260
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.81034623
68Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.78872346
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78649976
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.78422659
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.77589570
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74722696
73VEGF signaling pathway_Homo sapiens_hsa043700.74468760
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.73431205
75Sulfur relay system_Homo sapiens_hsa041220.72709356
76Hippo signaling pathway_Homo sapiens_hsa043900.71521446
77Thyroid hormone synthesis_Homo sapiens_hsa049180.69922288
78MAPK signaling pathway_Homo sapiens_hsa040100.69846842
79Adherens junction_Homo sapiens_hsa045200.69112119
80Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67705940
81mTOR signaling pathway_Homo sapiens_hsa041500.66675948
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66325928
83Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.65449114
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64778289
85Colorectal cancer_Homo sapiens_hsa052100.64668094
86Pancreatic secretion_Homo sapiens_hsa049720.61468422
87Wnt signaling pathway_Homo sapiens_hsa043100.59889429
88Circadian rhythm_Homo sapiens_hsa047100.59280319
89beta-Alanine metabolism_Homo sapiens_hsa004100.58929935
90Proteasome_Homo sapiens_hsa030500.55876756
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55826189
92Fatty acid elongation_Homo sapiens_hsa000620.55399042
93Phospholipase D signaling pathway_Homo sapiens_hsa040720.55248153
94Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55196016
95RNA polymerase_Homo sapiens_hsa030200.55035816
96Base excision repair_Homo sapiens_hsa034100.54952879
97Endometrial cancer_Homo sapiens_hsa052130.54664305
98Spliceosome_Homo sapiens_hsa030400.51827894
99Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.51021016
100Central carbon metabolism in cancer_Homo sapiens_hsa052300.48585901
101Choline metabolism in cancer_Homo sapiens_hsa052310.48581099
102Endocytosis_Homo sapiens_hsa041440.47880288
103Type I diabetes mellitus_Homo sapiens_hsa049400.47552095
104Biosynthesis of amino acids_Homo sapiens_hsa012300.47237129
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46399009
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46282670
107Ras signaling pathway_Homo sapiens_hsa040140.46015497
108HIF-1 signaling pathway_Homo sapiens_hsa040660.44949356
109SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44202540
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44062590
111Non-small cell lung cancer_Homo sapiens_hsa052230.43960740
112RNA transport_Homo sapiens_hsa030130.43674575
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.43201173
114Huntingtons disease_Homo sapiens_hsa050160.43131387
115Dilated cardiomyopathy_Homo sapiens_hsa054140.42250720
116Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42124052
117Insulin signaling pathway_Homo sapiens_hsa049100.41078966
118Renal cell carcinoma_Homo sapiens_hsa052110.40965587
119Inositol phosphate metabolism_Homo sapiens_hsa005620.38955183
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.37465990
121Alzheimers disease_Homo sapiens_hsa050100.35059462
122Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.34423203
123Rap1 signaling pathway_Homo sapiens_hsa040150.33951631
124mRNA surveillance pathway_Homo sapiens_hsa030150.32727324
125African trypanosomiasis_Homo sapiens_hsa051430.30919255
126Pyruvate metabolism_Homo sapiens_hsa006200.27670928
127N-Glycan biosynthesis_Homo sapiens_hsa005100.24979619
128Salmonella infection_Homo sapiens_hsa051320.23985348
129Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.23896388
130Fatty acid biosynthesis_Homo sapiens_hsa000610.23540242
131Hedgehog signaling pathway_Homo sapiens_hsa043400.22579193

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