Rank | Gene Set | Z-score |
---|---|---|
1 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.11044449 |
2 | L-phenylalanine catabolic process (GO:0006559) | 7.11044449 |
3 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 6.89087211 |
4 | L-phenylalanine metabolic process (GO:0006558) | 6.89087211 |
5 | aromatic amino acid family catabolic process (GO:0009074) | 6.09233381 |
6 | glyoxylate metabolic process (GO:0046487) | 5.75542277 |
7 | cysteine metabolic process (GO:0006534) | 5.62869791 |
8 | serine family amino acid biosynthetic process (GO:0009070) | 5.29813792 |
9 | type I interferon signaling pathway (GO:0060337) | 5.27347447 |
10 | cellular response to type I interferon (GO:0071357) | 5.27347447 |
11 | response to type I interferon (GO:0034340) | 5.20136860 |
12 | indole-containing compound catabolic process (GO:0042436) | 5.19238446 |
13 | indolalkylamine catabolic process (GO:0046218) | 5.19238446 |
14 | tryptophan catabolic process (GO:0006569) | 5.19238446 |
15 | kynurenine metabolic process (GO:0070189) | 5.03638640 |
16 | bile acid biosynthetic process (GO:0006699) | 4.99873805 |
17 | serine family amino acid metabolic process (GO:0009069) | 4.95120504 |
18 | tryptophan metabolic process (GO:0006568) | 4.92305036 |
19 | serine family amino acid catabolic process (GO:0009071) | 4.87300898 |
20 | glycine metabolic process (GO:0006544) | 4.84349373 |
21 | immunoglobulin mediated immune response (GO:0016064) | 4.83866469 |
22 | sulfur amino acid catabolic process (GO:0000098) | 4.80235783 |
23 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 4.77640856 |
24 | L-serine metabolic process (GO:0006563) | 4.67655829 |
25 | lysine catabolic process (GO:0006554) | 4.66055375 |
26 | lysine metabolic process (GO:0006553) | 4.66055375 |
27 | homocysteine metabolic process (GO:0050667) | 4.55136423 |
28 | alpha-linolenic acid metabolic process (GO:0036109) | 4.53201474 |
29 | aromatic amino acid family metabolic process (GO:0009072) | 4.49842759 |
30 | interferon-gamma-mediated signaling pathway (GO:0060333) | 4.46163736 |
31 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.36337914 |
32 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.34813958 |
33 | aldehyde catabolic process (GO:0046185) | 4.34062154 |
34 | alpha-amino acid catabolic process (GO:1901606) | 4.30073614 |
35 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.29581224 |
36 | urea cycle (GO:0000050) | 4.21001859 |
37 | urea metabolic process (GO:0019627) | 4.21001859 |
38 | bile acid metabolic process (GO:0008206) | 4.20738598 |
39 | negative regulation of interleukin-12 production (GO:0032695) | 4.15017680 |
40 | heme transport (GO:0015886) | 4.13399793 |
41 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.12588873 |
42 | acetyl-CoA metabolic process (GO:0006084) | 4.12332577 |
43 | cellular amino acid catabolic process (GO:0009063) | 4.09625133 |
44 | amino-acid betaine metabolic process (GO:0006577) | 4.08818584 |
45 | regulation of interferon-alpha production (GO:0032647) | 4.07850571 |
46 | ethanol oxidation (GO:0006069) | 4.06291883 |
47 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.06128694 |
48 | B cell mediated immunity (GO:0019724) | 4.04617742 |
49 | high-density lipoprotein particle remodeling (GO:0034375) | 4.02998647 |
50 | aspartate family amino acid catabolic process (GO:0009068) | 4.01766216 |
51 | negative regulation of fibrinolysis (GO:0051918) | 4.01123564 |
52 | nitrogen cycle metabolic process (GO:0071941) | 4.00483877 |
53 | fatty acid elongation (GO:0030497) | 3.98601548 |
54 | drug transmembrane transport (GO:0006855) | 3.98427117 |
55 | response to peptidoglycan (GO:0032494) | 3.97721319 |
56 | tyrosine metabolic process (GO:0006570) | 3.97003099 |
57 | regulation of triglyceride catabolic process (GO:0010896) | 3.96529434 |
58 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.94608846 |
59 | protein carboxylation (GO:0018214) | 3.94608846 |
60 | positive regulation of type 2 immune response (GO:0002830) | 3.93215814 |
61 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.92646603 |
62 | positive regulation of interferon-alpha production (GO:0032727) | 3.91922422 |
63 | urate metabolic process (GO:0046415) | 3.90678422 |
64 | regulation of protein activation cascade (GO:2000257) | 3.89800619 |
65 | macrophage activation involved in immune response (GO:0002281) | 3.89206190 |
66 | cellular modified amino acid catabolic process (GO:0042219) | 3.87764575 |
67 | complement activation, alternative pathway (GO:0006957) | 3.87630104 |
68 | regulation of cholesterol esterification (GO:0010872) | 3.84557407 |
69 | glutamate metabolic process (GO:0006536) | 3.81049479 |
70 | short-chain fatty acid metabolic process (GO:0046459) | 3.76782735 |
71 | regulation of fibrinolysis (GO:0051917) | 3.76346785 |
72 | negative regulation of sterol transport (GO:0032372) | 3.76344382 |
73 | negative regulation of cholesterol transport (GO:0032375) | 3.76344382 |
74 | response to nitrosative stress (GO:0051409) | 3.73484911 |
75 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.73272257 |
76 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.72516016 |
77 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.72516016 |
78 | modulation by symbiont of host immune response (GO:0052553) | 3.72516016 |
79 | positive regulation by symbiont of host defense response (GO:0052509) | 3.72516016 |
80 | modulation by symbiont of host defense response (GO:0052031) | 3.72516016 |
81 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.72516016 |
82 | cellular glucuronidation (GO:0052695) | 3.72340053 |
83 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.72150888 |
84 | coenzyme catabolic process (GO:0009109) | 3.71775287 |
85 | amine catabolic process (GO:0009310) | 3.69261751 |
86 | cellular biogenic amine catabolic process (GO:0042402) | 3.69261751 |
87 | drug catabolic process (GO:0042737) | 3.68498061 |
88 | regulation of complement activation (GO:0030449) | 3.66836738 |
89 | response to interferon-beta (GO:0035456) | 3.64942346 |
90 | plasma lipoprotein particle clearance (GO:0034381) | 3.64805932 |
91 | indolalkylamine metabolic process (GO:0006586) | 3.63838472 |
92 | myeloid dendritic cell differentiation (GO:0043011) | 3.62859773 |
93 | regulation of antigen processing and presentation (GO:0002577) | 3.62324304 |
94 | response to interferon-alpha (GO:0035455) | 3.61906626 |
95 | cellular response to interferon-gamma (GO:0071346) | 3.61599574 |
96 | negative regulation of viral genome replication (GO:0045071) | 3.61337149 |
97 | positive regulation of antigen processing and presentation (GO:0002579) | 3.61178508 |
98 | T-helper 1 type immune response (GO:0042088) | 3.59599177 |
99 | carboxylic acid catabolic process (GO:0046395) | 3.58825406 |
100 | organic acid catabolic process (GO:0016054) | 3.58825406 |
101 | cellular ketone body metabolic process (GO:0046950) | 3.56361911 |
102 | very long-chain fatty acid metabolic process (GO:0000038) | 3.55782243 |
103 | branched-chain amino acid catabolic process (GO:0009083) | 3.53053693 |
104 | protein-lipid complex remodeling (GO:0034368) | 3.50217354 |
105 | macromolecular complex remodeling (GO:0034367) | 3.50217354 |
106 | plasma lipoprotein particle remodeling (GO:0034369) | 3.50217354 |
107 | reverse cholesterol transport (GO:0043691) | 3.50103897 |
108 | detection of molecule of bacterial origin (GO:0032490) | 3.49348184 |
109 | triglyceride homeostasis (GO:0070328) | 3.47850147 |
110 | acylglycerol homeostasis (GO:0055090) | 3.47850147 |
111 | uronic acid metabolic process (GO:0006063) | 3.47603340 |
112 | glucuronate metabolic process (GO:0019585) | 3.47603340 |
113 | benzene-containing compound metabolic process (GO:0042537) | 3.46244830 |
114 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.45789844 |
115 | imidazole-containing compound metabolic process (GO:0052803) | 3.45165229 |
116 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 3.44386269 |
117 | detection of other organism (GO:0098543) | 3.44218186 |
118 | response to interferon-gamma (GO:0034341) | 3.43946028 |
119 | fatty acid beta-oxidation (GO:0006635) | 3.42615139 |
120 | cholesterol homeostasis (GO:0042632) | 3.41633181 |
121 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.39696310 |
122 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.39696310 |
123 | drug transport (GO:0015893) | 3.38357872 |
124 | sterol homeostasis (GO:0055092) | 3.37596970 |
125 | cholesterol biosynthetic process (GO:0006695) | 3.36541599 |
126 | NIK/NF-kappaB signaling (GO:0038061) | 3.35941852 |
127 | cellular response to interferon-alpha (GO:0035457) | 3.34180167 |
128 | myeloid dendritic cell activation (GO:0001773) | 3.33480281 |
129 | regulation of bile acid biosynthetic process (GO:0070857) | 3.32010630 |
130 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.31751055 |
131 | bile acid and bile salt transport (GO:0015721) | 3.31053067 |
132 | fatty acid oxidation (GO:0019395) | 3.30858517 |
133 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.30704265 |
134 | drug metabolic process (GO:0017144) | 3.30697873 |
135 | T cell migration (GO:0072678) | 3.30203314 |
136 | cofactor catabolic process (GO:0051187) | 3.30027167 |
137 | detection of bacterium (GO:0016045) | 3.29640570 |
138 | branched-chain amino acid metabolic process (GO:0009081) | 3.25976091 |
139 | cholesterol efflux (GO:0033344) | 3.25968978 |
140 | lipid oxidation (GO:0034440) | 3.25614196 |
141 | exogenous drug catabolic process (GO:0042738) | 3.25593155 |
142 | regulation of mononuclear cell migration (GO:0071675) | 3.25231507 |
143 | detection of external biotic stimulus (GO:0098581) | 3.24759782 |
144 | regulation of cholesterol metabolic process (GO:0090181) | 3.24759082 |
145 | acyl-CoA metabolic process (GO:0006637) | 3.24753312 |
146 | thioester metabolic process (GO:0035383) | 3.24753312 |
147 | regulation of T cell tolerance induction (GO:0002664) | 3.18672717 |
148 | neutrophil activation involved in immune response (GO:0002283) | 3.17747380 |
149 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.16930145 |
150 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.16472098 |
151 | cellular response to interferon-beta (GO:0035458) | 3.09051757 |
152 | regulation of vitamin metabolic process (GO:0030656) | 3.08438062 |
153 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.06267504 |
154 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.05482718 |
155 | lymphocyte chemotaxis (GO:0048247) | 3.03957574 |
156 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.03872324 |
157 | dendritic cell differentiation (GO:0097028) | 3.00791104 |
158 | defense response to protozoan (GO:0042832) | 3.00495967 |
159 | regulation of type 2 immune response (GO:0002828) | 2.99584911 |
160 | regulation of cytokine secretion involved in immune response (GO:0002739) | 2.99145018 |
161 | positive regulation of interferon-beta production (GO:0032728) | 2.95568306 |
162 | defense response to virus (GO:0051607) | 2.94265482 |
163 | negative regulation of cell killing (GO:0031342) | 2.93020106 |
164 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.93020106 |
165 | regulation of hypersensitivity (GO:0002883) | 2.92079790 |
166 | regulation of interleukin-12 production (GO:0032655) | 2.91633078 |
167 | regulation of podosome assembly (GO:0071801) | 2.88479446 |
168 | response to protozoan (GO:0001562) | 2.88163427 |
169 | regulation of RIG-I signaling pathway (GO:0039535) | 2.87894619 |
170 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.87865669 |
171 | regulation of tolerance induction (GO:0002643) | 2.87269069 |
172 | regulation of response to interferon-gamma (GO:0060330) | 2.87218888 |
173 | germinal center formation (GO:0002467) | 2.87177536 |
174 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.85551901 |
175 | regulation of macrophage chemotaxis (GO:0010758) | 2.83269735 |
176 | detection of biotic stimulus (GO:0009595) | 2.81737786 |
177 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.79030365 |
178 | response to host immune response (GO:0052572) | 2.79030365 |
179 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.77880883 |
180 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.76336513 |
181 | regulation of chronic inflammatory response (GO:0002676) | 2.74675764 |
182 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.73249275 |
183 | glycosphingolipid catabolic process (GO:0046479) | 2.72598629 |
184 | cellular response to exogenous dsRNA (GO:0071360) | 2.68288766 |
185 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.68168475 |
186 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.67730056 |
187 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.66027682 |
188 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.65166745 |
189 | pinocytosis (GO:0006907) | 2.64655828 |
190 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.63549567 |
191 | positive regulation of interleukin-12 production (GO:0032735) | 2.63330960 |
192 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.60439629 |
193 | eosinophil chemotaxis (GO:0048245) | 2.59049043 |
194 | myeloid cell activation involved in immune response (GO:0002275) | 2.58790946 |
195 | negative regulation of innate immune response (GO:0045824) | 2.56981925 |
196 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.56017238 |
197 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.55822730 |
198 | cellular response to lipopolysaccharide (GO:0071222) | 2.55194343 |
199 | response to host defenses (GO:0052200) | 2.51728323 |
200 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.51728323 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 8.81855013 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.26186674 |
3 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 5.96034993 |
4 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 5.28614029 |
5 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 5.12537416 |
6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 5.00212596 |
7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.69719318 |
8 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.67101540 |
9 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 4.58811938 |
10 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 4.06507019 |
11 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.98201882 |
12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.84248144 |
13 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.49544456 |
14 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 3.34693146 |
15 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.23005637 |
16 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.17170163 |
17 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.00892889 |
18 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.85858073 |
19 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.83930436 |
20 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.82025227 |
21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.77687452 |
22 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.59473373 |
23 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.53271079 |
24 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.50447665 |
25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.44775277 |
26 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.44394384 |
27 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.37298037 |
28 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.27632611 |
29 | GATA1_22025678_ChIP-Seq_K562_Human | 2.21766842 |
30 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.17815102 |
31 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.16454596 |
32 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.10825175 |
33 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.04953908 |
34 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.04145385 |
35 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.92678076 |
36 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.86616687 |
37 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.83811174 |
38 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.82089454 |
39 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.80532000 |
40 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.80467943 |
41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.80445425 |
42 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.80067794 |
43 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.80067794 |
44 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.80067794 |
45 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.77868152 |
46 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.77618328 |
47 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.76415323 |
48 | MYB_26560356_Chip-Seq_TH2_Human | 1.70968957 |
49 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.69563780 |
50 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.67790325 |
51 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.61729383 |
52 | * TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.61239357 |
53 | MAF_26560356_Chip-Seq_TH1_Human | 1.60913618 |
54 | SPI1_23127762_ChIP-Seq_K562_Human | 1.59830677 |
55 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.57996794 |
56 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.52678478 |
57 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.51676076 |
58 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50997758 |
59 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.50146616 |
60 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.49473462 |
61 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.48523841 |
62 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.48443081 |
63 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.48355676 |
64 | MYB_26560356_Chip-Seq_TH1_Human | 1.47294454 |
65 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.43842990 |
66 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.43508199 |
67 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.43329713 |
68 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.40173069 |
69 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40068346 |
70 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39541651 |
71 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.37524770 |
72 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.34702124 |
73 | MYC_22102868_ChIP-Seq_BL_Human | 1.34423501 |
74 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.33340653 |
75 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.32960752 |
76 | * SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.32949366 |
77 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.32763630 |
78 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29883370 |
79 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.29294398 |
80 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.28265272 |
81 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.25635425 |
82 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.25302072 |
83 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.24190308 |
84 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.24139599 |
85 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.23746617 |
86 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.23547013 |
87 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.22684279 |
88 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22578443 |
89 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.20889314 |
90 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.20685807 |
91 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.19655074 |
92 | * TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.16300581 |
93 | * NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.15562594 |
94 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.15123912 |
95 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.14920489 |
96 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.14562360 |
97 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.13517396 |
98 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.13367583 |
99 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.12889011 |
100 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.12808802 |
101 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.12305379 |
102 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.12025318 |
103 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.11554784 |
104 | UTX_26944678_Chip-Seq_JUKART_Human | 1.11530350 |
105 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.11212238 |
106 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.10603594 |
107 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.09445221 |
108 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.09333568 |
109 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08930839 |
110 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.08799955 |
111 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.08042816 |
112 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.07827867 |
113 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.06798463 |
114 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06772770 |
115 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.06397255 |
116 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.06236994 |
117 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04799431 |
118 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04640703 |
119 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.04524618 |
120 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.04217659 |
121 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04008407 |
122 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.03315143 |
123 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.02232037 |
124 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.02175536 |
125 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.01927240 |
126 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.01262105 |
127 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.01105859 |
128 | * MAF_26560356_Chip-Seq_TH2_Human | 0.98710112 |
129 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.98019611 |
130 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.97763643 |
131 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.97591874 |
132 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.96949851 |
133 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.96596352 |
134 | GATA3_26560356_Chip-Seq_TH2_Human | 0.95706731 |
135 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95264512 |
136 | * SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.94453615 |
137 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.92926073 |
138 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.92578507 |
139 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.92175610 |
140 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.91498275 |
141 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.91460264 |
142 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.90927618 |
143 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.90208813 |
144 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.89999525 |
145 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.87124159 |
146 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.86908366 |
147 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.86286410 |
148 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.86283242 |
149 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.86109781 |
150 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.85724367 |
151 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.85004777 |
152 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.84069775 |
153 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82144369 |
154 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.81617616 |
155 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.80939251 |
156 | * NANOG_18692474_ChIP-Seq_MESCs_Mouse | 0.80740915 |
157 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.80723127 |
158 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.79448456 |
159 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.79427189 |
160 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.78733710 |
161 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.78194326 |
162 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.76548142 |
163 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.76115858 |
164 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 0.75987141 |
165 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.75434342 |
166 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.74678136 |
167 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.74609289 |
168 | * POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 0.73565151 |
169 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.72625659 |
170 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.72344847 |
171 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.72073459 |
172 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.71912108 |
173 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.71319360 |
174 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.69997248 |
175 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.67508026 |
176 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.67399373 |
177 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.64696642 |
178 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.64604608 |
179 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.63546912 |
180 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.62405638 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 7.29428744 |
2 | MP0002139_abnormal_hepatobiliary_system | 7.03848262 |
3 | MP0003806_abnormal_nucleotide_metabolis | 6.13380752 |
4 | MP0005085_abnormal_gallbladder_physiolo | 5.21027196 |
5 | MP0005365_abnormal_bile_salt | 4.75681605 |
6 | MP0008875_abnormal_xenobiotic_pharmacok | 4.30481646 |
7 | MP0003303_peritoneal_inflammation | 4.05743534 |
8 | MP0001835_abnormal_antigen_presentation | 4.05252523 |
9 | MP0009840_abnormal_foam_cell | 3.39341610 |
10 | MP0003724_increased_susceptibility_to | 3.34835032 |
11 | MP0009785_altered_susceptibility_to | 3.34080814 |
12 | MP0005332_abnormal_amino_acid | 3.18647889 |
13 | MP0002148_abnormal_hypersensitivity_rea | 3.07068616 |
14 | MP0003252_abnormal_bile_duct | 2.97887656 |
15 | MP0003436_decreased_susceptibility_to | 2.88084161 |
16 | MP0003195_calcinosis | 2.84531873 |
17 | MP0005387_immune_system_phenotype | 2.83362306 |
18 | MP0001790_abnormal_immune_system | 2.83362306 |
19 | MP0005671_abnormal_response_to | 2.69500204 |
20 | MP0005000_abnormal_immune_tolerance | 2.68339795 |
21 | MP0010329_abnormal_lipoprotein_level | 2.61357752 |
22 | MP0005025_abnormal_response_to | 2.61086694 |
23 | MP0001666_abnormal_nutrient_absorption | 2.59996589 |
24 | MP0000685_abnormal_immune_system | 2.57168986 |
25 | MP0002419_abnormal_innate_immunity | 2.44098532 |
26 | MP0001800_abnormal_humoral_immune | 2.43212336 |
27 | MP0003300_gastrointestinal_ulcer | 2.34891886 |
28 | MP0004019_abnormal_vitamin_homeostasis | 2.31458967 |
29 | MP0002452_abnormal_antigen_presenting | 2.29756693 |
30 | MP0002723_abnormal_immune_serum | 2.20226654 |
31 | MP0005083_abnormal_biliary_tract | 2.16719755 |
32 | MP0003186_abnormal_redox_activity | 2.10730218 |
33 | MP0010155_abnormal_intestine_physiology | 1.94922770 |
34 | MP0003191_abnormal_cellular_cholesterol | 1.91131029 |
35 | MP0001819_abnormal_immune_cell | 1.88484234 |
36 | MP0000343_altered_response_to | 1.87636123 |
37 | MP0005451_abnormal_body_composition | 1.87482956 |
38 | MP0002420_abnormal_adaptive_immunity | 1.87447024 |
39 | MP0001845_abnormal_inflammatory_respons | 1.84462382 |
40 | MP0002118_abnormal_lipid_homeostasis | 1.77728296 |
41 | MP0001853_heart_inflammation | 1.77674277 |
42 | MP0003075_altered_response_to | 1.77188464 |
43 | MP0001533_abnormal_skeleton_physiology | 1.75100670 |
44 | MP0004947_skin_inflammation | 1.73169046 |
45 | MP0004510_myositis | 1.71592492 |
46 | MP0000609_abnormal_liver_physiology | 1.68683827 |
47 | MP0009643_abnormal_urine_homeostasis | 1.64967490 |
48 | MP0009333_abnormal_splenocyte_physiolog | 1.60396112 |
49 | MP0005319_abnormal_enzyme/_coenzyme | 1.59784819 |
50 | MP0005166_decreased_susceptibility_to | 1.56875451 |
51 | MP0001764_abnormal_homeostasis | 1.51843027 |
52 | MP0005464_abnormal_platelet_physiology | 1.51512808 |
53 | MP0003448_altered_tumor_morphology | 1.47417826 |
54 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.45968891 |
55 | MP0002405_respiratory_system_inflammati | 1.43226231 |
56 | MP0003172_abnormal_lysosome_physiology | 1.41449633 |
57 | MP0000716_abnormal_immune_system | 1.41295622 |
58 | MP0004043_abnormal_pH_regulation | 1.41016600 |
59 | MP0003705_abnormal_hypodermis_morpholog | 1.40094801 |
60 | MP0000858_altered_metastatic_potential | 1.39628187 |
61 | MP0002138_abnormal_hepatobiliary_system | 1.37076391 |
62 | MP0005310_abnormal_salivary_gland | 1.37025738 |
63 | MP0002166_altered_tumor_susceptibility | 1.31744695 |
64 | MP0002998_abnormal_bone_remodeling | 1.30354528 |
65 | MP0002398_abnormal_bone_marrow | 1.29963369 |
66 | MP0003690_abnormal_glial_cell | 1.28570375 |
67 | MP0008004_abnormal_stomach_pH | 1.28099396 |
68 | MP0003718_maternal_effect | 1.23306115 |
69 | MP0005397_hematopoietic_system_phenotyp | 1.22969459 |
70 | MP0001545_abnormal_hematopoietic_system | 1.22969459 |
71 | MP0002877_abnormal_melanocyte_morpholog | 1.19612401 |
72 | MP0003763_abnormal_thymus_physiology | 1.19560386 |
73 | MP0000920_abnormal_myelination | 1.18524560 |
74 | MP0003868_abnormal_feces_composition | 1.17455889 |
75 | MP0005408_hypopigmentation | 1.17441813 |
76 | MP0008260_abnormal_autophagy | 1.16297639 |
77 | MP0003011_delayed_dark_adaptation | 1.15701226 |
78 | MP0002429_abnormal_blood_cell | 1.15629707 |
79 | MP0006036_abnormal_mitochondrial_physio | 1.14318876 |
80 | MP0009278_abnormal_bone_marrow | 1.14124133 |
81 | MP0003950_abnormal_plasma_membrane | 1.11779885 |
82 | MP0000689_abnormal_spleen_morphology | 1.09693751 |
83 | MP0005167_abnormal_blood-brain_barrier | 1.09187738 |
84 | MP0001661_extended_life_span | 1.08293016 |
85 | MP0002796_impaired_skin_barrier | 1.07422588 |
86 | MP0005164_abnormal_response_to | 1.05406768 |
87 | MP0000598_abnormal_liver_morphology | 1.05325539 |
88 | MP0002722_abnormal_immune_system | 1.04253454 |
89 | MP0002006_tumorigenesis | 1.02813582 |
90 | MP0009697_abnormal_copulation | 1.02589470 |
91 | MP0005636_abnormal_mineral_homeostasis | 1.01161439 |
92 | MP0006054_spinal_hemorrhage | 0.98240780 |
93 | MP0005266_abnormal_metabolism | 0.97389530 |
94 | MP0003091_abnormal_cell_migration | 0.95831946 |
95 | MP0003656_abnormal_erythrocyte_physiolo | 0.95658891 |
96 | MP0005165_increased_susceptibility_to | 0.95341565 |
97 | MP0000604_amyloidosis | 0.91486913 |
98 | MP0003828_pulmonary_edema | 0.90442329 |
99 | MP0005058_abnormal_lysosome_morphology | 0.89854202 |
100 | MP0004883_abnormal_blood_vessel | 0.89421240 |
101 | MP0002332_abnormal_exercise_endurance | 0.87827641 |
102 | MP0005647_abnormal_sex_gland | 0.87645103 |
103 | MP0000465_gastrointestinal_hemorrhage | 0.86996104 |
104 | MP0003183_abnormal_peptide_metabolism | 0.86637726 |
105 | MP0009053_abnormal_anal_canal | 0.86427345 |
106 | MP0005376_homeostasis/metabolism_phenot | 0.85291855 |
107 | MP0009765_abnormal_xenobiotic_induced | 0.84336274 |
108 | MP0003329_amyloid_beta_deposits | 0.84076960 |
109 | MP0001756_abnormal_urination | 0.81888235 |
110 | MP0009763_increased_sensitivity_to | 0.79299906 |
111 | MP0003866_abnormal_defecation | 0.77927979 |
112 | MP0000249_abnormal_blood_vessel | 0.77903877 |
113 | MP0005395_other_phenotype | 0.76836493 |
114 | MP0002254_reproductive_system_inflammat | 0.75777588 |
115 | MP0002136_abnormal_kidney_physiology | 0.73426960 |
116 | MP0004808_abnormal_hematopoietic_stem | 0.73222756 |
117 | MP0005666_abnormal_adipose_tissue | 0.72364677 |
118 | MP0004147_increased_porphyrin_level | 0.71729153 |
119 | MP0001873_stomach_inflammation | 0.69416659 |
120 | MP0004264_abnormal_extraembryonic_tissu | 0.68855005 |
121 | MP0010234_abnormal_vibrissa_follicle | 0.68805536 |
122 | MP0004885_abnormal_endolymph | 0.68542963 |
123 | MP0010678_abnormal_skin_adnexa | 0.68152425 |
124 | MP0005501_abnormal_skin_physiology | 0.66707335 |
125 | MP0000579_abnormal_nail_morphology | 0.66452469 |
126 | MP0009764_decreased_sensitivity_to | 0.66415530 |
127 | MP0000462_abnormal_digestive_system | 0.65804089 |
128 | MP0001663_abnormal_digestive_system | 0.65415114 |
129 | MP0004133_heterotaxia | 0.65120076 |
130 | MP0005390_skeleton_phenotype | 0.64554115 |
131 | MP0004185_abnormal_adipocyte_glucose | 0.64521578 |
132 | MP0002098_abnormal_vibrissa_morphology | 0.64163463 |
133 | MP0006035_abnormal_mitochondrial_morpho | 0.63558378 |
134 | MP0008874_decreased_physiological_sensi | 0.63373217 |
135 | MP0003795_abnormal_bone_structure | 0.62428379 |
136 | MP0000647_abnormal_sebaceous_gland | 0.62306748 |
137 | MP0003453_abnormal_keratinocyte_physiol | 0.62247121 |
138 | MP0000467_abnormal_esophagus_morphology | 0.62063667 |
139 | MP0000490_abnormal_crypts_of | 0.61573973 |
140 | MP0008469_abnormal_protein_level | 0.60862809 |
141 | MP0009642_abnormal_blood_homeostasis | 0.60588613 |
142 | MP0005670_abnormal_white_adipose | 0.59981182 |
143 | MP0004957_abnormal_blastocyst_morpholog | 0.59699974 |
144 | MP0000377_abnormal_hair_follicle | 0.59282450 |
145 | MP0010307_abnormal_tumor_latency | 0.59037078 |
146 | MP0001730_embryonic_growth_arrest | 0.57757837 |
147 | MP0008438_abnormal_cutaneous_collagen | 0.56682239 |
148 | MP0008873_increased_physiological_sensi | 0.54653761 |
149 | MP0003136_yellow_coat_color | 0.54261808 |
150 | MP0005084_abnormal_gallbladder_morpholo | 0.53115259 |
151 | MP0004381_abnormal_hair_follicle | 0.52683179 |
152 | MP0000566_synostosis | 0.52677318 |
153 | MP0005220_abnormal_exocrine_pancreas | 0.51752164 |
154 | MP0001243_abnormal_dermal_layer | 0.51006679 |
155 | MP0003632_abnormal_nervous_system | 0.50424460 |
156 | MP0000537_abnormal_urethra_morphology | 0.47992855 |
157 | MP0005023_abnormal_wound_healing | 0.47263528 |
158 | MP0002971_abnormal_brown_adipose | 0.46161910 |
159 | MP0009672_abnormal_birth_weight | 0.42699337 |
160 | MP0002295_abnormal_pulmonary_circulatio | 0.41416678 |
161 | MP0000383_abnormal_hair_follicle | 0.41227205 |
162 | MP0006082_CNS_inflammation | 0.40241873 |
163 | MP0001293_anophthalmia | 0.38471737 |
164 | MP0009384_cardiac_valve_regurgitation | 0.37933654 |
165 | MP0000747_muscle_weakness | 0.37782032 |
166 | MP0003221_abnormal_cardiomyocyte_apopto | 0.37101288 |
167 | MP0001485_abnormal_pinna_reflex | 0.36553526 |
168 | MP0002269_muscular_atrophy | 0.36041857 |
169 | MP0010352_gastrointestinal_tract_polyps | 0.35737403 |
170 | MP0002111_abnormal_tail_morphology | 0.34734130 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Intrahepatic cholestasis (HP:0001406) | 6.62021666 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 6.37639455 |
3 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 5.69047459 |
4 | Hypobetalipoproteinemia (HP:0003563) | 5.45765090 |
5 | Xanthomatosis (HP:0000991) | 5.23494514 |
6 | Deep venous thrombosis (HP:0002625) | 5.03465638 |
7 | Abnormality of glycine metabolism (HP:0010895) | 4.87154564 |
8 | Abnormality of serine family amino acid metabolism (HP:0010894) | 4.87154564 |
9 | Hyperglycinuria (HP:0003108) | 4.78278772 |
10 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.68710353 |
11 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.68710353 |
12 | Abnormality of glycolipid metabolism (HP:0010969) | 4.68710353 |
13 | Hyperglycinemia (HP:0002154) | 4.61642404 |
14 | Recurrent bacterial skin infections (HP:0005406) | 4.48163133 |
15 | Hyperammonemia (HP:0001987) | 4.44906162 |
16 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.31617938 |
17 | Prolonged partial thromboplastin time (HP:0003645) | 4.27207111 |
18 | Abnormality of macrophages (HP:0004311) | 4.25811982 |
19 | Eczematoid dermatitis (HP:0000976) | 4.25683625 |
20 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.21810116 |
21 | Recurrent abscess formation (HP:0002722) | 4.20471200 |
22 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.18101698 |
23 | Hyperlipoproteinemia (HP:0010980) | 4.09866673 |
24 | Abnormality of methionine metabolism (HP:0010901) | 4.02668732 |
25 | Glomerulonephritis (HP:0000099) | 3.92605575 |
26 | Fat malabsorption (HP:0002630) | 3.86682847 |
27 | Orchitis (HP:0100796) | 3.84685567 |
28 | Hypolipoproteinemia (HP:0010981) | 3.83531117 |
29 | Optic neuritis (HP:0100653) | 3.77772248 |
30 | Retrobulbar optic neuritis (HP:0100654) | 3.77772248 |
31 | Complement deficiency (HP:0004431) | 3.77307140 |
32 | Ketosis (HP:0001946) | 3.71522646 |
33 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.59624288 |
34 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 3.57893389 |
35 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.52428489 |
36 | Myositis (HP:0100614) | 3.52107566 |
37 | Epidermoid cyst (HP:0200040) | 3.49221395 |
38 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.45911855 |
39 | Mediastinal lymphadenopathy (HP:0100721) | 3.41969037 |
40 | Hypoglycemic coma (HP:0001325) | 3.34424706 |
41 | Abnormality of serum amino acid levels (HP:0003112) | 3.24405077 |
42 | Recurrent viral infections (HP:0004429) | 3.23613870 |
43 | Delayed CNS myelination (HP:0002188) | 3.20866051 |
44 | Vacuolated lymphocytes (HP:0001922) | 3.15184203 |
45 | Vasculitis (HP:0002633) | 3.14678952 |
46 | Steatorrhea (HP:0002570) | 3.11186738 |
47 | Recurrent skin infections (HP:0001581) | 3.05687087 |
48 | Loss of speech (HP:0002371) | 3.04780164 |
49 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.02269464 |
50 | Increased serum pyruvate (HP:0003542) | 2.97606161 |
51 | Abnormality of glycolysis (HP:0004366) | 2.97606161 |
52 | Abnormality of nucleobase metabolism (HP:0010932) | 2.96834273 |
53 | Lethargy (HP:0001254) | 2.94140225 |
54 | Hypoalphalipoproteinemia (HP:0003233) | 2.93351494 |
55 | Colitis (HP:0002583) | 2.92195053 |
56 | Dicarboxylic aciduria (HP:0003215) | 2.91333235 |
57 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.91333235 |
58 | Pulmonary infiltrates (HP:0002113) | 2.88402285 |
59 | Increased IgM level (HP:0003496) | 2.87444607 |
60 | Recurrent fungal infections (HP:0002841) | 2.82999799 |
61 | Meningitis (HP:0001287) | 2.82152363 |
62 | Abnormality of the common coagulation pathway (HP:0010990) | 2.80477370 |
63 | Gout (HP:0001997) | 2.80201981 |
64 | Spastic diplegia (HP:0001264) | 2.79471089 |
65 | Dysostosis multiplex (HP:0000943) | 2.77312722 |
66 | Recurrent cutaneous fungal infections (HP:0011370) | 2.75949181 |
67 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.75949181 |
68 | Malnutrition (HP:0004395) | 2.74406037 |
69 | Joint hemorrhage (HP:0005261) | 2.74402672 |
70 | Abnormality of complement system (HP:0005339) | 2.71747146 |
71 | Vascular calcification (HP:0004934) | 2.70007921 |
72 | Recurrent bronchitis (HP:0002837) | 2.69127992 |
73 | Abnormality of purine metabolism (HP:0004352) | 2.69037165 |
74 | Conjugated hyperbilirubinemia (HP:0002908) | 2.68443922 |
75 | Ketoacidosis (HP:0001993) | 2.68251982 |
76 | Disinhibition (HP:0000734) | 2.68103356 |
77 | Keratoconjunctivitis sicca (HP:0001097) | 2.67146265 |
78 | Autoimmune thrombocytopenia (HP:0001973) | 2.66813797 |
79 | Gastrointestinal stroma tumor (HP:0100723) | 2.66498582 |
80 | Purpura (HP:0000979) | 2.63716110 |
81 | Chronic otitis media (HP:0000389) | 2.63626145 |
82 | Metabolic acidosis (HP:0001942) | 2.63029342 |
83 | Increased cerebral lipofuscin (HP:0011813) | 2.62626441 |
84 | Cerebral edema (HP:0002181) | 2.62336914 |
85 | Hemoptysis (HP:0002105) | 2.61862826 |
86 | Proximal tubulopathy (HP:0000114) | 2.59772414 |
87 | Obstructive lung disease (HP:0006536) | 2.57480613 |
88 | Chronic obstructive pulmonary disease (HP:0006510) | 2.57480613 |
89 | Gastrointestinal infarctions (HP:0005244) | 2.56908131 |
90 | Abnormality of the intrinsic pathway (HP:0010989) | 2.55586071 |
91 | Spastic paraparesis (HP:0002313) | 2.54667568 |
92 | Gingivitis (HP:0000230) | 2.52455359 |
93 | Hypercholesterolemia (HP:0003124) | 2.49327956 |
94 | Hyperbilirubinemia (HP:0002904) | 2.49090328 |
95 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.48463922 |
96 | IgA deficiency (HP:0002720) | 2.47081160 |
97 | Generalized aminoaciduria (HP:0002909) | 2.46518056 |
98 | Irritability (HP:0000737) | 2.45223245 |
99 | Rickets (HP:0002748) | 2.44160123 |
100 | Abnormality of the nasal mucosa (HP:0000433) | 2.41119845 |
101 | Nephritis (HP:0000123) | 2.39124488 |
102 | Autoimmune hemolytic anemia (HP:0001890) | 2.38725453 |
103 | Urticaria (HP:0001025) | 2.38229290 |
104 | Hypergammaglobulinemia (HP:0010702) | 2.37814805 |
105 | Cardiovascular calcification (HP:0011915) | 2.36154085 |
106 | Premature loss of primary teeth (HP:0006323) | 2.36137000 |
107 | Keratoconjunctivitis (HP:0001096) | 2.35085417 |
108 | Hepatocellular carcinoma (HP:0001402) | 2.34203729 |
109 | Glycosuria (HP:0003076) | 2.33240609 |
110 | Abnormality of urine glucose concentration (HP:0011016) | 2.33240609 |
111 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.30903375 |
112 | Arterial thrombosis (HP:0004420) | 2.30563151 |
113 | Interstitial pulmonary disease (HP:0006530) | 2.30290494 |
114 | Gangrene (HP:0100758) | 2.29976634 |
115 | Amyloidosis (HP:0011034) | 2.29808523 |
116 | Increased serum ferritin (HP:0003281) | 2.27668697 |
117 | Stomatitis (HP:0010280) | 2.26166485 |
118 | Cellulitis (HP:0100658) | 2.25115002 |
119 | Encephalitis (HP:0002383) | 2.25018460 |
120 | Inflammation of the large intestine (HP:0002037) | 2.21205705 |
121 | Vomiting (HP:0002013) | 2.21159872 |
122 | Basal ganglia calcification (HP:0002135) | 2.20216774 |
123 | Nasal polyposis (HP:0100582) | 2.19662329 |
124 | Abnormality of vitamin metabolism (HP:0100508) | 2.19194900 |
125 | Spontaneous hematomas (HP:0007420) | 2.18878684 |
126 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.18833135 |
127 | Alkalosis (HP:0001948) | 2.17497987 |
128 | Opisthotonus (HP:0002179) | 2.16580948 |
129 | Abnormality of T cell number (HP:0011839) | 2.15886961 |
130 | Osteomyelitis (HP:0002754) | 2.14849867 |
131 | Ileus (HP:0002595) | 2.14109952 |
132 | Increased purine levels (HP:0004368) | 2.11377421 |
133 | Hyperuricemia (HP:0002149) | 2.11377421 |
134 | Gastrointestinal inflammation (HP:0004386) | 2.10866847 |
135 | T lymphocytopenia (HP:0005403) | 2.10270538 |
136 | Axonal loss (HP:0003447) | 2.09658803 |
137 | Abnormality of proline metabolism (HP:0010907) | 2.09394832 |
138 | Hydroxyprolinuria (HP:0003080) | 2.09394832 |
139 | Abnormal cartilage morphology (HP:0002763) | 2.09108165 |
140 | Petechiae (HP:0000967) | 2.08241370 |
141 | Increased IgE level (HP:0003212) | 2.06465224 |
142 | Polyneuropathy (HP:0001271) | 2.06050200 |
143 | Hepatosplenomegaly (HP:0001433) | 2.05556475 |
144 | Hypophosphatemic rickets (HP:0004912) | 2.04427003 |
145 | Emphysema (HP:0002097) | 2.02810007 |
146 | Abnormality of the prostate (HP:0008775) | 2.02735884 |
147 | Agammaglobulinemia (HP:0004432) | 2.02734335 |
148 | Systemic lupus erythematosus (HP:0002725) | 2.02067282 |
149 | Pulmonary embolism (HP:0002204) | 2.01349829 |
150 | Megaloblastic anemia (HP:0001889) | 2.01247146 |
151 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.99668684 |
152 | Skin nodule (HP:0200036) | 1.99406116 |
153 | Mucopolysacchariduria (HP:0008155) | 1.98826966 |
154 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.98826966 |
155 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.98495768 |
156 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.98286751 |
157 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.98286751 |
158 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.98286751 |
159 | Restrictive lung disease (HP:0002091) | 1.97811994 |
160 | Hematochezia (HP:0002573) | 1.95798605 |
161 | Joint swelling (HP:0001386) | 1.94134226 |
162 | Back pain (HP:0003418) | 1.93969863 |
163 | Acanthocytosis (HP:0001927) | 1.93954467 |
164 | Confusion (HP:0001289) | 1.93924587 |
165 | Abnormal gallbladder morphology (HP:0012437) | 1.93467883 |
166 | Cerebral hypomyelination (HP:0006808) | 1.92530547 |
167 | Anorexia (HP:0002039) | 1.91843911 |
168 | Abnormality of the pleura (HP:0002103) | 1.91003768 |
169 | Progressive neurologic deterioration (HP:0002344) | 1.90883438 |
170 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.90426036 |
171 | Chronic diarrhea (HP:0002028) | 1.90182481 |
172 | Enlarged kidneys (HP:0000105) | 1.88929667 |
173 | Brushfield spots (HP:0001088) | 1.88838838 |
174 | IgM deficiency (HP:0002850) | 1.88574098 |
175 | Pancreatitis (HP:0001733) | 1.86769233 |
176 | Abnormality of iron homeostasis (HP:0011031) | 1.86320177 |
177 | Methylmalonic aciduria (HP:0012120) | 1.85624928 |
178 | Prolonged neonatal jaundice (HP:0006579) | 1.85529053 |
179 | Gingival bleeding (HP:0000225) | 1.85458371 |
180 | Glomerulopathy (HP:0100820) | 1.85157303 |
181 | Nausea (HP:0002018) | 1.83308220 |
182 | Elevated alkaline phosphatase (HP:0003155) | 1.81966188 |
183 | Neurofibrillary tangles (HP:0002185) | 1.81732273 |
184 | Myocardial infarction (HP:0001658) | 1.79390951 |
185 | Cholelithiasis (HP:0001081) | 1.79266433 |
186 | Cholecystitis (HP:0001082) | 1.79005968 |
187 | Abnormal gallbladder physiology (HP:0012438) | 1.79005968 |
188 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.76663256 |
189 | Hypoglycemic seizures (HP:0002173) | 1.76272893 |
190 | Parakeratosis (HP:0001036) | 1.73438622 |
191 | Acute encephalopathy (HP:0006846) | 1.72722068 |
192 | CNS demyelination (HP:0007305) | 1.72215016 |
193 | Sensorimotor neuropathy (HP:0007141) | 1.70428898 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 5.46889953 |
2 | STK39 | 4.44256632 |
3 | TYK2 | 3.97079063 |
4 | PBK | 3.67888285 |
5 | OXSR1 | 3.63805069 |
6 | IRAK3 | 3.53632764 |
7 | BLK | 3.14985908 |
8 | RIPK4 | 3.10853709 |
9 | MET | 3.06680966 |
10 | MAP3K14 | 3.01227369 |
11 | WNK4 | 2.62382306 |
12 | TBK1 | 2.59704537 |
13 | JAK3 | 2.54856559 |
14 | EPHA2 | 2.53134397 |
15 | MAP4K1 | 2.50278416 |
16 | IKBKE | 2.48473913 |
17 | PRPF4B | 2.43630614 |
18 | JAK1 | 2.43550206 |
19 | ERBB4 | 2.36099071 |
20 | TESK2 | 2.26989885 |
21 | MST4 | 2.24002113 |
22 | BMPR2 | 2.22451666 |
23 | IRAK4 | 2.17309105 |
24 | EPHB1 | 2.08611830 |
25 | RIPK1 | 2.05425062 |
26 | GRK7 | 1.92049831 |
27 | EIF2AK1 | 1.88814708 |
28 | FGFR4 | 1.76234692 |
29 | MATK | 1.73138819 |
30 | KIT | 1.70187935 |
31 | TAOK2 | 1.67290762 |
32 | BCR | 1.65811961 |
33 | BUB1 | 1.63761453 |
34 | WEE1 | 1.62408367 |
35 | ERN1 | 1.61598914 |
36 | IKBKB | 1.59664313 |
37 | FGR | 1.56056427 |
38 | SIK1 | 1.53993892 |
39 | MAP3K13 | 1.53855100 |
40 | FGFR2 | 1.49028359 |
41 | ICK | 1.42890792 |
42 | TTK | 1.35468753 |
43 | FGFR3 | 1.32874687 |
44 | MST1R | 1.31645782 |
45 | LATS1 | 1.29363618 |
46 | TGFBR2 | 1.28665622 |
47 | NME2 | 1.28334063 |
48 | CSF1R | 1.26740520 |
49 | ABL2 | 1.26188972 |
50 | ZAP70 | 1.25258958 |
51 | SYK | 1.23057363 |
52 | JAK2 | 1.19503850 |
53 | NEK1 | 1.19251804 |
54 | PIK3CG | 1.17682604 |
55 | WNK3 | 1.15262371 |
56 | STK38L | 1.14551537 |
57 | PIM2 | 1.13546681 |
58 | CDC42BPA | 1.11506309 |
59 | MAP3K8 | 1.10967039 |
60 | PKN1 | 1.10731522 |
61 | LYN | 1.10684723 |
62 | MOS | 1.09992676 |
63 | PDK2 | 1.09741354 |
64 | MARK3 | 1.08759888 |
65 | CSNK1G3 | 1.06633293 |
66 | TXK | 1.05783748 |
67 | MAP3K1 | 1.03345445 |
68 | STK10 | 1.01190279 |
69 | BTK | 1.00061810 |
70 | LIMK1 | 0.98591630 |
71 | FLT3 | 0.98249756 |
72 | SMG1 | 0.97935185 |
73 | CSNK1G1 | 0.96841787 |
74 | CSNK1A1L | 0.91238588 |
75 | STK16 | 0.90095812 |
76 | MAP2K2 | 0.88084825 |
77 | RPS6KB2 | 0.88071310 |
78 | EIF2AK3 | 0.87648711 |
79 | TLK1 | 0.86938628 |
80 | AKT3 | 0.85718202 |
81 | IRAK1 | 0.83298346 |
82 | MAPK11 | 0.82661155 |
83 | PDK3 | 0.79634756 |
84 | PDK4 | 0.79634756 |
85 | STK4 | 0.77586937 |
86 | GSK3A | 0.76926631 |
87 | LCK | 0.76712142 |
88 | MAP3K5 | 0.75967042 |
89 | MAP3K11 | 0.74810254 |
90 | CAMK2G | 0.71889185 |
91 | MAP3K3 | 0.71408087 |
92 | HCK | 0.70914471 |
93 | FES | 0.69591649 |
94 | BMX | 0.69018759 |
95 | CHUK | 0.67931029 |
96 | AURKA | 0.63330056 |
97 | CDK7 | 0.62284171 |
98 | NEK9 | 0.61886434 |
99 | EPHA3 | 0.61797996 |
100 | NEK6 | 0.60824789 |
101 | LRRK2 | 0.60097566 |
102 | TEC | 0.59524907 |
103 | ARAF | 0.59268874 |
104 | MELK | 0.58472478 |
105 | TAOK1 | 0.57227923 |
106 | WNK1 | 0.55823790 |
107 | STK3 | 0.54716484 |
108 | CLK1 | 0.54697198 |
109 | IRAK2 | 0.54530138 |
110 | PINK1 | 0.53737923 |
111 | SCYL2 | 0.50766381 |
112 | PAK1 | 0.50747743 |
113 | PNCK | 0.50302376 |
114 | CDK4 | 0.47914584 |
115 | PAK4 | 0.47090679 |
116 | ERBB2 | 0.46195217 |
117 | CSNK1E | 0.46050445 |
118 | ROCK2 | 0.45684648 |
119 | ITK | 0.45231631 |
120 | PIM1 | 0.45111631 |
121 | FGFR1 | 0.44848523 |
122 | TSSK6 | 0.44769597 |
123 | KDR | 0.44316209 |
124 | PTK6 | 0.44211643 |
125 | STK24 | 0.43343140 |
126 | CSNK2A2 | 0.43187234 |
127 | PDK1 | 0.42693938 |
128 | ACVR1B | 0.42533253 |
129 | SIK3 | 0.41415754 |
130 | MAP2K3 | 0.41192977 |
131 | CSNK1G2 | 0.40748654 |
132 | PDGFRA | 0.40337953 |
133 | EIF2AK2 | 0.40311238 |
134 | DYRK2 | 0.39789575 |
135 | MAPKAPK2 | 0.39783947 |
136 | CDK6 | 0.39543146 |
137 | PDPK1 | 0.39371904 |
138 | TRIB3 | 0.39322520 |
139 | PTK2 | 0.39272414 |
140 | MTOR | 0.39170181 |
141 | CSNK1D | 0.38737244 |
142 | HIPK2 | 0.38298467 |
143 | EGFR | 0.36503221 |
144 | PLK1 | 0.36464973 |
145 | CSK | 0.35296267 |
146 | PKN2 | 0.35181566 |
147 | ALK | 0.34095237 |
148 | ABL1 | 0.33517702 |
149 | DDR2 | 0.31949988 |
150 | AURKB | 0.31924932 |
151 | DAPK3 | 0.31024866 |
152 | PRKCI | 0.30957264 |
153 | PAK3 | 0.30793985 |
154 | PAK2 | 0.30658380 |
155 | CAMK2B | 0.30406472 |
156 | RPS6KA5 | 0.28673381 |
157 | PRKCD | 0.28658248 |
158 | CSNK2A1 | 0.28598374 |
159 | PRKCQ | 0.27605720 |
160 | MAPK15 | 0.27110945 |
161 | GRK6 | 0.26290496 |
162 | MAPK7 | 0.26188629 |
163 | ADRBK2 | 0.25520092 |
164 | CAMK2D | 0.24884084 |
165 | CDK19 | 0.24645751 |
166 | BRSK2 | 0.23062450 |
167 | PRKG2 | 0.22979791 |
168 | TESK1 | 0.22802321 |
169 | MAPK4 | 0.21982803 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Allograft rejection_Homo sapiens_hsa05330 | 3.63206993 |
2 | Asthma_Homo sapiens_hsa05310 | 3.39832871 |
3 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 3.37341704 |
4 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.19859905 |
5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.18523491 |
6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.09481008 |
7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.95588604 |
8 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.90664255 |
9 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.84851096 |
10 | Leishmaniasis_Homo sapiens_hsa05140 | 2.84515745 |
11 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.71788726 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.55719222 |
13 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.53398192 |
14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.49818731 |
15 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.44665430 |
16 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.43705467 |
17 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.41823034 |
18 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.34624687 |
19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.31762095 |
20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.31759372 |
21 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.29487107 |
22 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.22282052 |
23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.22149874 |
24 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.19698644 |
25 | Other glycan degradation_Homo sapiens_hsa00511 | 2.14638789 |
26 | Influenza A_Homo sapiens_hsa05164 | 2.12094884 |
27 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.11280586 |
28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.09908878 |
29 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.09435490 |
30 | Peroxisome_Homo sapiens_hsa04146 | 2.07797110 |
31 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.06424576 |
32 | Tuberculosis_Homo sapiens_hsa05152 | 2.00314629 |
33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.99574103 |
34 | Viral myocarditis_Homo sapiens_hsa05416 | 1.97729916 |
35 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.93479577 |
36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.90706998 |
37 | Histidine metabolism_Homo sapiens_hsa00340 | 1.89906759 |
38 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.89900788 |
39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.89441506 |
40 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.87401205 |
41 | Pertussis_Homo sapiens_hsa05133 | 1.85348882 |
42 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.83183242 |
43 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.82227038 |
44 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.79042997 |
45 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.76985088 |
46 | Measles_Homo sapiens_hsa05162 | 1.75229150 |
47 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.73250042 |
48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.72890361 |
49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.68201077 |
50 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.67380213 |
51 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.67335475 |
52 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.66724530 |
53 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.62670678 |
54 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.61295830 |
55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.60783923 |
56 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.58785199 |
57 | Lysosome_Homo sapiens_hsa04142 | 1.57801466 |
58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.57799823 |
59 | Malaria_Homo sapiens_hsa05144 | 1.55840738 |
60 | Legionellosis_Homo sapiens_hsa05134 | 1.54928908 |
61 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.54836413 |
62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.51550937 |
63 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.50590957 |
64 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.49879870 |
65 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.49766824 |
66 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.49016676 |
67 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.47813838 |
68 | Phagosome_Homo sapiens_hsa04145 | 1.43757515 |
69 | Carbon metabolism_Homo sapiens_hsa01200 | 1.42935016 |
70 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.41187343 |
71 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.40337522 |
72 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.40266350 |
73 | Retinol metabolism_Homo sapiens_hsa00830 | 1.39194350 |
74 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.38844657 |
75 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.37074143 |
76 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.36220635 |
77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.33807337 |
78 | Hepatitis C_Homo sapiens_hsa05160 | 1.33503093 |
79 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.32455755 |
80 | * Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.28782192 |
81 | * Glutathione metabolism_Homo sapiens_hsa00480 | 1.26978843 |
82 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.26622212 |
83 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.26023186 |
84 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.21392377 |
85 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.19679212 |
86 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.12540031 |
87 | Sulfur relay system_Homo sapiens_hsa04122 | 1.09780917 |
88 | Bile secretion_Homo sapiens_hsa04976 | 1.08657097 |
89 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.05857487 |
90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.05742270 |
91 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.04137775 |
92 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.03277587 |
93 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.02364420 |
94 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.01362308 |
95 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.01313323 |
96 | Salmonella infection_Homo sapiens_hsa05132 | 0.99399348 |
97 | Apoptosis_Homo sapiens_hsa04210 | 0.99306578 |
98 | Hepatitis B_Homo sapiens_hsa05161 | 0.97603573 |
99 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.96425564 |
100 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.88773471 |
101 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.86433957 |
102 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.84469490 |
103 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.82831476 |
104 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.82046940 |
105 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.75345028 |
106 | Shigellosis_Homo sapiens_hsa05131 | 0.73656052 |
107 | ABC transporters_Homo sapiens_hsa02010 | 0.70642819 |
108 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.70061865 |
109 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.66919651 |
110 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.65221982 |
111 | Proteasome_Homo sapiens_hsa03050 | 0.64957770 |
112 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.63520997 |
113 | Lysine degradation_Homo sapiens_hsa00310 | 0.61190687 |
114 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.60218421 |
115 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.60199501 |
116 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.57663406 |
117 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.55500428 |
118 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54680355 |
119 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.53493652 |
120 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.52499387 |
121 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.52017337 |
122 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.51938182 |
123 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.49214514 |
124 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.48258231 |
125 | HTLV-I infection_Homo sapiens_hsa05166 | 0.48115413 |
126 | Bladder cancer_Homo sapiens_hsa05219 | 0.47936107 |
127 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.47683174 |
128 | Amoebiasis_Homo sapiens_hsa05146 | 0.44986555 |
129 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.43967764 |
130 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.42074871 |
131 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.40684708 |
132 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.38786903 |
133 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.37840281 |
134 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.35185443 |
135 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32776943 |
136 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.32659271 |
137 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32185163 |
138 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31793381 |
139 | Galactose metabolism_Homo sapiens_hsa00052 | 0.31559629 |
140 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.30910525 |
141 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.29390776 |
142 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.27255809 |
143 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.27137699 |
144 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26317807 |
145 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.25701212 |
146 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.25182159 |
147 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.24772956 |
148 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.24195504 |
149 | Protein export_Homo sapiens_hsa03060 | 0.23266232 |
150 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.23066384 |
151 | Mismatch repair_Homo sapiens_hsa03430 | 0.22230899 |
152 | Prion diseases_Homo sapiens_hsa05020 | 0.21632211 |
153 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.20173260 |
154 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.16104622 |
155 | RNA polymerase_Homo sapiens_hsa03020 | 0.16014424 |
156 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.14057465 |
157 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.13793523 |
158 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.13739032 |
159 | Mineral absorption_Homo sapiens_hsa04978 | 0.13250530 |
160 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.13084333 |
161 | Platelet activation_Homo sapiens_hsa04611 | 0.13064599 |
162 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.13033183 |
163 | DNA replication_Homo sapiens_hsa03030 | 0.11369891 |
164 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.10965964 |
165 | Parkinsons disease_Homo sapiens_hsa05012 | 0.08278486 |
166 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.03463531 |
167 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.02780506 |
168 | Ribosome_Homo sapiens_hsa03010 | 0.01193556 |
169 | Nucleotide excision repair_Homo sapiens_hsa03420 | -0.0318066 |
170 | Tight junction_Homo sapiens_hsa04530 | -0.0284470 |
171 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | -0.0171899 |
172 | RNA transport_Homo sapiens_hsa03013 | -0.0141345 |