LARP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.84448315
2nuclear pore organization (GO:0006999)5.54344930
3pre-miRNA processing (GO:0031054)4.85328320
4folic acid-containing compound biosynthetic process (GO:0009396)4.56365642
5regulation of translational fidelity (GO:0006450)4.53408470
6heterochromatin organization (GO:0070828)4.47617782
7regulation of translational termination (GO:0006449)4.37636477
8pore complex assembly (GO:0046931)4.29672400
9mitotic nuclear envelope disassembly (GO:0007077)4.08291155
10protein complex localization (GO:0031503)4.02009016
11protein localization to kinetochore (GO:0034501)3.99404240
12regulation of RNA export from nucleus (GO:0046831)3.94648343
13mitotic sister chromatid cohesion (GO:0007064)3.94403895
14NLS-bearing protein import into nucleus (GO:0006607)3.93814244
15cellular protein complex localization (GO:0034629)3.89417313
16membrane disassembly (GO:0030397)3.86870920
17nuclear envelope disassembly (GO:0051081)3.86870920
18mRNA stabilization (GO:0048255)3.85153765
19RNA stabilization (GO:0043489)3.85153765
20DNA unwinding involved in DNA replication (GO:0006268)3.68521726
21protein localization to chromosome, centromeric region (GO:0071459)3.58634093
22negative regulation of histone methylation (GO:0031061)3.42380962
23regulation of histone H3-K9 methylation (GO:0051570)3.33320402
24positive regulation of histone deacetylation (GO:0031065)3.30652796
25COPI coating of Golgi vesicle (GO:0048205)3.26885226
26Golgi transport vesicle coating (GO:0048200)3.26885226
27gene silencing by RNA (GO:0031047)3.26275526
28chromatin assembly (GO:0031497)3.26168101
29IMP biosynthetic process (GO:0006188)3.25377970
30sister chromatid segregation (GO:0000819)3.21616588
31DNA duplex unwinding (GO:0032508)3.20353426
32regulation of nucleobase-containing compound transport (GO:0032239)3.18328552
33DNA geometric change (GO:0032392)3.17474628
34protein localization to microtubule (GO:0035372)3.16337177
35nucleosome disassembly (GO:0006337)3.16135102
36protein-DNA complex disassembly (GO:0032986)3.16135102
37adherens junction assembly (GO:0034333)3.16075835
38nuclear envelope organization (GO:0006998)3.14942122
39glucocorticoid receptor signaling pathway (GO:0042921)3.12830318
40peptidyl-lysine dimethylation (GO:0018027)3.11227319
41dosage compensation (GO:0007549)3.11123077
42mitotic sister chromatid segregation (GO:0000070)3.10136408
43cell-substrate adherens junction assembly (GO:0007045)3.08986947
44focal adhesion assembly (GO:0048041)3.08986947
45spliceosomal tri-snRNP complex assembly (GO:0000244)3.08135073
46positive regulation of chromosome segregation (GO:0051984)3.08034217
473-UTR-mediated mRNA stabilization (GO:0070935)3.07360252
48gene silencing (GO:0016458)3.06161170
49regulation of histone H3-K27 methylation (GO:0061085)3.06018785
50DNA strand elongation involved in DNA replication (GO:0006271)3.05673024
51trophectodermal cell differentiation (GO:0001829)3.05143215
52DNA replication initiation (GO:0006270)3.04775817
53tetrahydrofolate metabolic process (GO:0046653)3.02670355
54cytoskeletal anchoring at plasma membrane (GO:0007016)3.02085632
55regulation of mammary gland epithelial cell proliferation (GO:0033599)3.00932656
56DNA strand elongation (GO:0022616)2.99974800
57histone H2A monoubiquitination (GO:0035518)2.99660026
58planar cell polarity pathway involved in neural tube closure (GO:0090179)2.99148062
59regulation of gene silencing by RNA (GO:0060966)2.97665110
60regulation of posttranscriptional gene silencing (GO:0060147)2.97665110
61regulation of gene silencing by miRNA (GO:0060964)2.97665110
62cytoplasmic mRNA processing body assembly (GO:0033962)2.97513832
63monoubiquitinated protein deubiquitination (GO:0035520)2.93457967
64positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.93273456
65positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.93273456
66positive regulation of mitotic sister chromatid separation (GO:1901970)2.93273456
67chaperone-mediated protein complex assembly (GO:0051131)2.92099561
68regulation of mRNA stability (GO:0043488)2.91877360
69mitotic chromosome condensation (GO:0007076)2.91704546
70DNA topological change (GO:0006265)2.90831838
71establishment of integrated proviral latency (GO:0075713)2.88865108
72regulation of mitotic spindle organization (GO:0060236)2.85680857
73regulation of spindle organization (GO:0090224)2.84850551
74DNA replication-dependent nucleosome organization (GO:0034723)2.84743705
75DNA replication-dependent nucleosome assembly (GO:0006335)2.84743705
76paraxial mesoderm development (GO:0048339)2.84198374
77regulation of hippo signaling (GO:0035330)2.83935983
78proline biosynthetic process (GO:0006561)2.82609473
79intracellular estrogen receptor signaling pathway (GO:0030520)2.80234829
80regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.79970183
81cellular response to epidermal growth factor stimulus (GO:0071364)2.78446605
82mitotic metaphase plate congression (GO:0007080)2.77598674
83regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.76927740
84activation of Rac GTPase activity (GO:0032863)2.76769177
85IMP metabolic process (GO:0046040)2.75850423
86regulation of chromatin binding (GO:0035561)2.75666141
87chromatin silencing (GO:0006342)2.74994240
88negative regulation of mRNA metabolic process (GO:1903312)2.74764833
89corticosteroid receptor signaling pathway (GO:0031958)2.74631035
90negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.74138751
91regulation of RNA stability (GO:0043487)2.74115935
92positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.71757020
93regulation of NFAT protein import into nucleus (GO:0051532)2.70637440
94regulation of translational elongation (GO:0006448)2.70059915
95positive regulation of DNA-dependent DNA replication (GO:2000105)2.69221906
96mitotic G1 DNA damage checkpoint (GO:0031571)2.68789938
97positive regulation of SMAD protein import into nucleus (GO:0060391)2.66831888
98response to UV-C (GO:0010225)2.65916593
99L-serine metabolic process (GO:0006563)2.65494222
100regulation of glucose import in response to insulin stimulus (GO:2001273)2.65487065
101chromosome condensation (GO:0030261)2.65204328
102protein export from nucleus (GO:0006611)2.65054563
103regulation of histone H3-K4 methylation (GO:0051569)2.64946303
104L-alpha-amino acid transmembrane transport (GO:1902475)2.64185479
105formation of translation preinitiation complex (GO:0001731)2.64025751
106desmosome organization (GO:0002934)2.63106936
107glycine metabolic process (GO:0006544)2.62520786
108maternal placenta development (GO:0001893)2.61887293
109folic acid metabolic process (GO:0046655)2.61243001
110negative regulation of DNA repair (GO:0045738)2.59562749
111protein localization to chromosome (GO:0034502)2.59279156
112DNA conformation change (GO:0071103)2.59047344
113cell-substrate junction assembly (GO:0007044)2.58956673
114apoptotic process involved in morphogenesis (GO:0060561)2.58754644
115negative regulation of mRNA processing (GO:0050686)2.57686756
116negative regulation of cell size (GO:0045792)2.56604792
117nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.56333765
118mRNA cleavage (GO:0006379)2.54775530
119hippo signaling (GO:0035329)2.54658020
120mRNA transport (GO:0051028)2.53934225
121regulation of early endosome to late endosome transport (GO:2000641)2.52704048
122regulation of sister chromatid cohesion (GO:0007063)2.51433266
123response to epidermal growth factor (GO:0070849)2.49695017
124establishment of apical/basal cell polarity (GO:0035089)2.48679003
125nucleobase biosynthetic process (GO:0046112)2.47967218
126positive regulation of protein import into nucleus, translocation (GO:0033160)2.47676711
127histone H4-K12 acetylation (GO:0043983)2.46969255
128DNA packaging (GO:0006323)2.46231893
129positive regulation of gene expression, epigenetic (GO:0045815)2.45353554
130positive regulation of cell cycle G2/M phase transition (GO:1902751)2.45280856
131positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.45280856
132translesion synthesis (GO:0019985)2.43585087
133mitotic G1/S transition checkpoint (GO:0044819)2.42606066
134cellular hyperosmotic response (GO:0071474)2.42131016
135ribosome assembly (GO:0042255)2.41109762
136negative regulation of RNA splicing (GO:0033119)2.40324063
137folic acid-containing compound metabolic process (GO:0006760)2.40188888
138regulation of histone methylation (GO:0031060)2.39933033
139snRNA metabolic process (GO:0016073)2.39931905
140peptidyl-arginine omega-N-methylation (GO:0035247)2.38970798
141negative regulation of gene expression, epigenetic (GO:0045814)2.38832842
142convergent extension (GO:0060026)2.38144167
143negative regulation of histone modification (GO:0031057)2.36868842
144one-carbon metabolic process (GO:0006730)2.36386396
145retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.32296049
146embryonic camera-type eye morphogenesis (GO:0048596)2.31515916
147maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.30665611
148DNA replication checkpoint (GO:0000076)2.29296646

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.06598817
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.48124022
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.78014141
4MYC_22102868_ChIP-Seq_BL_Human3.37574582
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.17700085
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.58780647
7E2F4_17652178_ChIP-ChIP_JURKAT_Human2.43857782
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.40291757
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.37821067
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.30143625
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.18390408
12MYC_19079543_ChIP-ChIP_MESCs_Mouse2.02120198
13TCF7_22412390_ChIP-Seq_EML_Mouse1.94349550
14VDR_21846776_ChIP-Seq_THP-1_Human1.91100119
15ZNF263_19887448_ChIP-Seq_K562_Human1.89495470
16STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.88591930
17* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.85855711
18AR_21909140_ChIP-Seq_LNCAP_Human1.82946693
19KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.82554226
20KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.79918818
21KDM2B_26808549_Chip-Seq_DND41_Human1.77167394
22TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73181693
23STAT3_1855785_ChIP-Seq_MESCs_Mouse1.70558230
24TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.68957696
25E2F1_21310950_ChIP-Seq_MCF-7_Human1.68269508
26SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.65009832
27WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.61120256
28PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.59635484
29ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.53532588
30CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.51592501
31MAF_26560356_Chip-Seq_TH1_Human1.50033054
32MYC_19030024_ChIP-ChIP_MESCs_Mouse1.48776961
33ELK3_25401928_ChIP-Seq_HUVEC_Human1.46824104
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.46728052
35UTX_26944678_Chip-Seq_JUKART_Human1.45679718
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.44070668
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.43844905
38KDM5A_27292631_Chip-Seq_BREAST_Human1.43030823
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40932074
40* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.39420026
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.38126205
42KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37520950
43CIITA_25753668_ChIP-Seq_RAJI_Human1.36381206
44DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.36065461
45STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35576431
46ATF3_27146783_Chip-Seq_COLON_Human1.35175640
47TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.34619170
48NCOR1_26117541_ChIP-Seq_K562_Human1.30638359
49XRN2_22483619_ChIP-Seq_HELA_Human1.29943842
50ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.28050416
51* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.26121528
52* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.25848298
53* KDM2B_26808549_Chip-Seq_K562_Human1.25334878
54MYB_26560356_Chip-Seq_TH1_Human1.24676479
55POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.24163649
56SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.23526569
57KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.22597302
58TP63_17297297_ChIP-ChIP_HaCaT_Human1.22223305
59POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.20154491
60P300_27058665_Chip-Seq_ZR-75-30cells_Human1.20079518
61HIF1A_21447827_ChIP-Seq_MCF-7_Human1.19975408
62* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.18278370
63ESR1_15608294_ChIP-ChIP_MCF-7_Human1.18260364
64NELFA_20434984_ChIP-Seq_ESCs_Mouse1.17242922
65ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.17218438
66MYC_18358816_ChIP-ChIP_MESCs_Mouse1.16731526
67CHD1_26751641_Chip-Seq_LNCaP_Human1.15579073
68DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13565180
69CLOCK_20551151_ChIP-Seq_293T_Human1.13362756
70KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.12552729
71* RACK7_27058665_Chip-Seq_MCF-7_Human1.12229568
72MAF_26560356_Chip-Seq_TH2_Human1.11502514
73GATA6_25053715_ChIP-Seq_YYC3_Human1.10984028
74STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.09616208
75TTF2_22483619_ChIP-Seq_HELA_Human1.09564309
76RXR_22158963_ChIP-Seq_LIVER_Mouse1.08406569
77CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.07341342
78MYB_26560356_Chip-Seq_TH2_Human1.07212864
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.06979432
80* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.06549783
81ZFP281_27345836_Chip-Seq_ESCs_Mouse1.06288340
82TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.06198042
83ZFP281_18757296_ChIP-ChIP_E14_Mouse1.05891535
84TFEB_21752829_ChIP-Seq_HELA_Human1.05481720
85NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.04835457
86ZFX_18555785_ChIP-Seq_MESCs_Mouse1.03054070
87KDM2B_26808549_Chip-Seq_JURKAT_Human1.03023589
88NANOG_21062744_ChIP-ChIP_HESCs_Human1.02695368
89NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.02494595
90SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00557082
91TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99834557
92CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99663728
93SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.99451871
94DCP1A_22483619_ChIP-Seq_HELA_Human0.99447649
95ESR2_21235772_ChIP-Seq_MCF-7_Human0.98894172
96TP63_19390658_ChIP-ChIP_HaCaT_Human0.98462678
97TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.97599079
98* LXR_22292898_ChIP-Seq_THP-1_Human0.97499462
99NANOG_18555785_ChIP-Seq_MESCs_Mouse0.96997067
100CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.95937279
101NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95756679
102PKCTHETA_26484144_Chip-Seq_BREAST_Human0.95336445
103EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.95096205
104RUNX1_22412390_ChIP-Seq_EML_Mouse0.94600798
105E2F1_18555785_ChIP-Seq_MESCs_Mouse0.94376017
106KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.94144682
107KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.94144682
108KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.94144682
109VDR_24763502_ChIP-Seq_THP-1_Human0.93407890
110TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.93400285
111ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93233479
112CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.93065626
113ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.92855710
114UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.92548808
115SOX2_27498859_Chip-Seq_STOMACH_Mouse0.91857097
116FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.91282919
117HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90599560
118SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90411284
119SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.89777670
120UBF1/2_26484160_Chip-Seq_HMECs_Human0.89089571
121CREB1_26743006_Chip-Seq_LNCaP_Human0.88996591
122E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.88212950
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.87589798
124* SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.87397400
125RARG_19884340_ChIP-ChIP_MEFs_Mouse0.87272852
126KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86850474
127TP53_22127205_ChIP-Seq_IMR90_Human0.86826789
128EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.85920292
129MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.85715643
130DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85289079

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.78530973
2MP0010352_gastrointestinal_tract_polyps3.70554100
3MP0005076_abnormal_cell_differentiation3.17557559
4MP0003111_abnormal_nucleus_morphology2.73518294
5MP0003693_abnormal_embryo_hatching2.52362738
6MP0010307_abnormal_tumor_latency2.44928077
7MP0008057_abnormal_DNA_replication2.39291463
8MP0004957_abnormal_blastocyst_morpholog2.35131664
9MP0010094_abnormal_chromosome_stability2.30503379
10MP0003300_gastrointestinal_ulcer2.25791177
11MP0003077_abnormal_cell_cycle2.20081265
12MP0001730_embryonic_growth_arrest2.19798024
13MP0003941_abnormal_skin_development2.18186589
14MP0003566_abnormal_cell_adhesion1.90109641
15MP0003303_peritoneal_inflammation1.87585703
16MP0000350_abnormal_cell_proliferation1.85011997
17MP0004197_abnormal_fetal_growth/weight/1.84953248
18MP0005409_darkened_coat_color1.84787826
19MP0001672_abnormal_embryogenesis/_devel1.82978869
20MP0005380_embryogenesis_phenotype1.82978869
21MP0003984_embryonic_growth_retardation1.80550708
22MP0002088_abnormal_embryonic_growth/wei1.80048431
23MP0002396_abnormal_hematopoietic_system1.79737947
24MP0002796_impaired_skin_barrier1.75482001
25MP0009278_abnormal_bone_marrow1.75180408
26MP0002086_abnormal_extraembryonic_tissu1.70494529
27MP0005451_abnormal_body_composition1.69963947
28MP0002009_preneoplasia1.69866334
29MP0002084_abnormal_developmental_patter1.58829443
30MP0001697_abnormal_embryo_size1.57789109
31MP0004808_abnormal_hematopoietic_stem1.56303741
32MP0000579_abnormal_nail_morphology1.55560718
33MP0004185_abnormal_adipocyte_glucose1.50038027
34MP0002080_prenatal_lethality1.45282081
35MP0002877_abnormal_melanocyte_morpholog1.43080679
36MP0009672_abnormal_birth_weight1.42611333
37MP0001545_abnormal_hematopoietic_system1.41571222
38MP0005397_hematopoietic_system_phenotyp1.41571222
39MP0010234_abnormal_vibrissa_follicle1.40617115
40MP0002085_abnormal_embryonic_tissue1.37212066
41MP0001849_ear_inflammation1.37091960
42MP0005257_abnormal_intraocular_pressure1.36455244
43MP0004264_abnormal_extraembryonic_tissu1.36398206
44MP0000733_abnormal_muscle_development1.32297619
45MP0008961_abnormal_basal_metabolism1.31791628
46MP0005501_abnormal_skin_physiology1.31617629
47MP0005023_abnormal_wound_healing1.30953651
48MP0008438_abnormal_cutaneous_collagen1.29279218
49MP0005083_abnormal_biliary_tract1.29168828
50MP0000566_synostosis1.29117788
51MP0004272_abnormal_basement_membrane1.28481386
52MP0008007_abnormal_cellular_replicative1.25089646
53MP0002060_abnormal_skin_morphology1.24345261
54MP0003567_abnormal_fetal_cardiomyocyte1.23020068
55MP0009053_abnormal_anal_canal1.22984038
56MP0004858_abnormal_nervous_system1.22821029
57MP0008877_abnormal_DNA_methylation1.22511801
58MP0003942_abnormal_urinary_system1.21466851
59MP0009840_abnormal_foam_cell1.20224599
60MP0001661_extended_life_span1.17294034
61MP0009703_decreased_birth_body1.15904063
62MP0009780_abnormal_chondrocyte_physiolo1.15551479
63MP0000003_abnormal_adipose_tissue1.15194797
64MP0003123_paternal_imprinting1.15143250
65MP0002139_abnormal_hepatobiliary_system1.14459611
66MP0005410_abnormal_fertilization1.13944956
67MP0001915_intracranial_hemorrhage1.13084562
68MP0002089_abnormal_postnatal_growth/wei1.12683818
69MP0003890_abnormal_embryonic-extraembry1.12181321
70MP0010030_abnormal_orbit_morphology1.10873209
71MP0005623_abnormal_meninges_morphology1.09508699
72MP0001348_abnormal_lacrimal_gland1.07274907
73MP0000703_abnormal_thymus_morphology1.06717029
74MP0003283_abnormal_digestive_organ1.05964099
75MP0005360_urolithiasis1.05849449
76MP0000678_abnormal_parathyroid_gland1.05089002
77MP0002019_abnormal_tumor_incidence1.04829380
78MP0001346_abnormal_lacrimal_gland1.04138314
79MP0005666_abnormal_adipose_tissue1.03579128
80MP0003252_abnormal_bile_duct1.03526474
81MP0000313_abnormal_cell_death1.02100238
82MP0004233_abnormal_muscle_weight1.01684050
83MP0005365_abnormal_bile_salt1.01645279
84MP0000490_abnormal_crypts_of1.01525514
85MP0001299_abnormal_eye_distance/0.99118693
86MP0000762_abnormal_tongue_morphology0.98743281
87MP0010630_abnormal_cardiac_muscle0.98624931
88MP0000609_abnormal_liver_physiology0.98595317
89MP0003763_abnormal_thymus_physiology0.97505973
90MP0000534_abnormal_ureter_morphology0.96985258
91MP0003115_abnormal_respiratory_system0.95944599
92MP0008770_decreased_survivor_rate0.94956772
93MP0009333_abnormal_splenocyte_physiolog0.94782294
94MP0000432_abnormal_head_morphology0.94472802
95MP0000462_abnormal_digestive_system0.93099843
96MP0002398_abnormal_bone_marrow0.92453026
97MP0003937_abnormal_limbs/digits/tail_de0.92342553
98MP0002925_abnormal_cardiovascular_devel0.91710366
99MP0003861_abnormal_nervous_system0.90866014
100MP0000598_abnormal_liver_morphology0.89619605
101MP0000377_abnormal_hair_follicle0.88505583
102MP0003935_abnormal_craniofacial_develop0.87063418
103MP0002249_abnormal_larynx_morphology0.87010696
104MP0002653_abnormal_ependyma_morphology0.86560364
105MP0005375_adipose_tissue_phenotype0.85674400
106MP0000627_abnormal_mammary_gland0.85504496
107MP0004947_skin_inflammation0.85324911
108MP0002722_abnormal_immune_system0.84646249
109MP0005384_cellular_phenotype0.84521703
110MP0000858_altered_metastatic_potential0.84216586
111MP0003091_abnormal_cell_migration0.84065557
112MP0002166_altered_tumor_susceptibility0.83998487
113MP0008058_abnormal_DNA_repair0.83634927
114MP0003436_decreased_susceptibility_to0.82908653
115MP0008932_abnormal_embryonic_tissue0.82823563
116MP0005621_abnormal_cell_physiology0.81812191
117MP0003453_abnormal_keratinocyte_physiol0.81277284
118MP0005085_abnormal_gallbladder_physiolo0.80881595
119MP0003385_abnormal_body_wall0.80736474
120MP0002269_muscular_atrophy0.80636331
121MP0003119_abnormal_digestive_system0.80320311
122MP0000266_abnormal_heart_morphology0.80093315
123MP0000685_abnormal_immune_system0.79999405
124MP0002254_reproductive_system_inflammat0.79566059
125MP0000428_abnormal_craniofacial_morphol0.79030088
126MP0003315_abnormal_perineum_morphology0.78429287
127MP0002111_abnormal_tail_morphology0.78162210
128MP0001216_abnormal_epidermal_layer0.77660364
129MP0000689_abnormal_spleen_morphology0.76951803
130MP0000537_abnormal_urethra_morphology0.76694656
131MP0003448_altered_tumor_morphology0.76489252
132MP0003806_abnormal_nucleotide_metabolis0.75926738
133MP0001293_anophthalmia0.75795783
134MP0002081_perinatal_lethality0.74894705
135MP0004087_abnormal_muscle_fiber0.74859388
136MP0005670_abnormal_white_adipose0.74819312
137MP0002697_abnormal_eye_size0.74713014
138MP0002405_respiratory_system_inflammati0.74523971
139MP0002092_abnormal_eye_morphology0.74344628
140MP0001929_abnormal_gametogenesis0.72786598
141MP0010678_abnormal_skin_adnexa0.72725121
142MP0000467_abnormal_esophagus_morphology0.72609236
143MP0002114_abnormal_axial_skeleton0.72466219
144MP0003221_abnormal_cardiomyocyte_apopto0.72286477

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)3.32638951
2Abnormality of the lower motor neuron (HP:0002366)2.91520789
3Abnormality of the fingertips (HP:0001211)2.84401368
4Hyperacusis (HP:0010780)2.80947238
5Asymmetry of the thorax (HP:0001555)2.78331467
6Heterotopia (HP:0002282)2.75903437
7Deviation of the thumb (HP:0009603)2.73563216
8Pseudobulbar signs (HP:0002200)2.66613631
9Proximal placement of thumb (HP:0009623)2.65459063
10Abnormality of the astrocytes (HP:0100707)2.65379233
11Astrocytoma (HP:0009592)2.65379233
12Nasal polyposis (HP:0100582)2.64660820
13Cerebral aneurysm (HP:0004944)2.53793592
14Ankyloglossia (HP:0010296)2.52692269
15Increased density of long bones (HP:0006392)2.47900018
16Hand muscle atrophy (HP:0009130)2.47496405
17Increased nuchal translucency (HP:0010880)2.43846983
18Upper limb amyotrophy (HP:0009129)2.40585302
19Distal upper limb amyotrophy (HP:0007149)2.40585302
20Obstructive sleep apnea (HP:0002870)2.40078495
21Selective tooth agenesis (HP:0001592)2.38023793
22Advanced eruption of teeth (HP:0006288)2.34998981
23Impulsivity (HP:0100710)2.34489342
24Overriding aorta (HP:0002623)2.32953515
25Prominent nose (HP:0000448)2.32405487
26High pitched voice (HP:0001620)2.28286679
27Rectal prolapse (HP:0002035)2.27006152
28Reticulocytosis (HP:0001923)2.25766562
29Broad face (HP:0000283)2.25729715
30Chromsome breakage (HP:0040012)2.25482901
31Long eyelashes (HP:0000527)2.23589789
32Septate vagina (HP:0001153)2.22949971
33Sparse lateral eyebrow (HP:0005338)2.22620254
34Chromosomal breakage induced by crosslinking agents (HP:0003221)2.21314130
35Macroorchidism (HP:0000053)2.18890711
36Premature rupture of membranes (HP:0001788)2.18578470
37Dysmetric saccades (HP:0000641)2.18274605
38Basal cell carcinoma (HP:0002671)2.17237869
39Long palpebral fissure (HP:0000637)2.16589949
40Biliary tract neoplasm (HP:0100574)2.14586277
41Increased connective tissue (HP:0009025)2.12786531
42Urethral obstruction (HP:0000796)2.10500700
43Abnormality of the salivary glands (HP:0010286)2.10121920
44Abnormality of the nasal mucosa (HP:0000433)2.09862764
45High anterior hairline (HP:0009890)2.08839013
46Abnormality of the distal phalanx of the thumb (HP:0009617)2.07478264
47Renovascular hypertension (HP:0100817)2.07008615
48Termporal pattern (HP:0011008)2.05273984
49Insidious onset (HP:0003587)2.05273984
50Skin tags (HP:0010609)2.04140660
51Volvulus (HP:0002580)2.03966748
52Disproportionate tall stature (HP:0001519)2.02259634
53Rhabdomyosarcoma (HP:0002859)2.02117034
54Short 4th metacarpal (HP:0010044)2.01575371
55Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.01575371
56Difficulty climbing stairs (HP:0003551)2.01380798
57Neoplasm of striated muscle (HP:0009728)2.01104163
58Abnormality of oral frenula (HP:0000190)2.00360923
59Back pain (HP:0003418)1.98261337
60Medulloblastoma (HP:0002885)1.97595183
61Genu recurvatum (HP:0002816)1.97367861
62Patellar dislocation (HP:0002999)1.97021519
63Ulnar bowing (HP:0003031)1.96956752
64Achilles tendon contracture (HP:0001771)1.96252048
65Abnormality of the Achilles tendon (HP:0005109)1.96160390
66Malignant gastrointestinal tract tumors (HP:0006749)1.94500477
67Gastrointestinal carcinoma (HP:0002672)1.94500477
68Shallow orbits (HP:0000586)1.93333825
69Arnold-Chiari malformation (HP:0002308)1.92058292
70Glioma (HP:0009733)1.91111008
71Cutis marmorata (HP:0000965)1.91069466
72Obsessive-compulsive behavior (HP:0000722)1.89519385
73Multiple enchondromatosis (HP:0005701)1.88575496
74Mitral valve prolapse (HP:0001634)1.87965103
75Progressive muscle weakness (HP:0003323)1.85568347
76Protrusio acetabuli (HP:0003179)1.85310472
77Aneurysm (HP:0002617)1.83153264
78Flat acetabular roof (HP:0003180)1.82293028
79Myocardial infarction (HP:0001658)1.81533317
80Fibroma (HP:0010614)1.81361933
81Spastic diplegia (HP:0001264)1.80204810
82Precocious puberty (HP:0000826)1.80058293
83Fibrous tissue neoplasm (HP:0012316)1.79561129
84Neonatal hypoglycemia (HP:0001998)1.79269687
85Trigonocephaly (HP:0000243)1.78226223
86Elfin facies (HP:0004428)1.78104621
87Distal lower limb amyotrophy (HP:0008944)1.77720372
88Sandal gap (HP:0001852)1.76698550
89Adenoma sebaceum (HP:0009720)1.76322744
90Angiofibromas (HP:0010615)1.76322744
91Degeneration of anterior horn cells (HP:0002398)1.76040956
92Abnormality of the anterior horn cell (HP:0006802)1.76040956
93Nephroblastoma (Wilms tumor) (HP:0002667)1.75980183
94Renal duplication (HP:0000075)1.74803778
95Lower limb amyotrophy (HP:0007210)1.74247810
96Cortical dysplasia (HP:0002539)1.73949867
97Deep venous thrombosis (HP:0002625)1.73930754
98Abnormality of homocysteine metabolism (HP:0010919)1.73815842
99Homocystinuria (HP:0002156)1.73815842
100Pointed chin (HP:0000307)1.73685744
101Cafe-au-lait spot (HP:0000957)1.72825026
102Preauricular skin tag (HP:0000384)1.71791490
103Cutaneous melanoma (HP:0012056)1.70722686
104Subacute progressive viral hepatitis (HP:0006572)1.70589422
105Neoplasm of the oral cavity (HP:0100649)1.70217557
106Skull defect (HP:0001362)1.70197834
107Ulnar deviation of the wrist (HP:0003049)1.70186571
108Truncal obesity (HP:0001956)1.70113960
109Vertebral arch anomaly (HP:0008438)1.69914970
110Natal tooth (HP:0000695)1.69452702
111Turricephaly (HP:0000262)1.69438453
112Anal stenosis (HP:0002025)1.69048839
113Hyporeflexia of lower limbs (HP:0002600)1.68792848
114Large earlobe (HP:0009748)1.68491423
115Abnormality of chromosome segregation (HP:0002916)1.68210756
116Relative macrocephaly (HP:0004482)1.68204459
117Right ventricular cardiomyopathy (HP:0011663)1.67297639
118Abnormality of the phalanges of the hallux (HP:0010057)1.66944528
119Esophageal varix (HP:0002040)1.66409989
120Leiomyosarcoma (HP:0100243)1.66096909
121Uterine leiomyosarcoma (HP:0002891)1.66096909
122Abnormality of the calcaneus (HP:0008364)1.65960238
123Osteolytic defects of the hand bones (HP:0009699)1.65863083
124Osteolytic defects of the phalanges of the hand (HP:0009771)1.65863083
125Short humerus (HP:0005792)1.65745868
126Bowel diverticulosis (HP:0005222)1.65412475
127Deep palmar crease (HP:0006191)1.65299106
128Fragile skin (HP:0001030)1.64554909
129Frequent falls (HP:0002359)1.63830747
130Ankle contracture (HP:0006466)1.63811549
131Abnormality of the 4th metacarpal (HP:0010012)1.63452027
132Overlapping toe (HP:0001845)1.63267593
133Insomnia (HP:0100785)1.62338831
134Germ cell neoplasia (HP:0100728)1.62171550
135Embryonal renal neoplasm (HP:0011794)1.61251836
136Trismus (HP:0000211)1.60887749
137Broad palm (HP:0001169)1.60596065
138Enlarged penis (HP:0000040)1.60241701
139Cholecystitis (HP:0001082)1.59986169
140Abnormal gallbladder physiology (HP:0012438)1.59986169
141Hammertoe (HP:0001765)1.59373954
142Abnormality of reticulocytes (HP:0004312)1.59234244
143Abnormality of the peritoneum (HP:0002585)1.58786715
144Flat cornea (HP:0007720)1.58489441
145Missing ribs (HP:0000921)1.58335664
146Metaphyseal cupping (HP:0003021)1.57441019
147Broad thumb (HP:0011304)1.57139619
148Increased mean platelet volume (HP:0011877)1.57095089
149Abnormality of monocarboxylic acid metabolism (HP:0010996)1.57095077
150Unilateral renal agenesis (HP:0000122)1.56664587
151Attention deficit hyperactivity disorder (HP:0007018)1.56523528
152Low anterior hairline (HP:0000294)1.55748731
153Bronchomalacia (HP:0002780)1.55252743
154Progressive external ophthalmoplegia (HP:0000590)1.54838572
155Hypopigmentation of the fundus (HP:0007894)1.54190089
156Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.54105186
157Deep philtrum (HP:0002002)1.53870547
158Impaired pain sensation (HP:0007328)1.52220864
159Abnormality of pain sensation (HP:0010832)1.52220864
160Generalized hypotonia (HP:0001290)1.52045240

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.57028505
2CDK124.39079530
3SMG13.81675674
4TRIB33.53053236
5PKN23.28309104
6MAP3K102.79992749
7CDC72.26548680
8NEK22.23091681
9ICK2.14350263
10EIF2AK12.04966364
11STK101.78909545
12ALK1.75883833
13ERN11.71457271
14PRPF4B1.65594550
15MAP3K91.65461500
16MAP4K11.64394176
17TTN1.59232444
18IRAK31.54952604
19* MTOR1.53959584
20CDK41.52764964
21TAF11.50515843
22LATS11.50332204
23PTK61.48868077
24RPS6KB21.47574144
25STK31.38930742
26NEK11.38909347
27SIK11.37647253
28CDK61.37312748
29BUB11.36733150
30SCYL21.36043203
31PDK31.35444455
32PDK41.35444455
33MST1R1.34528203
34RIPK11.32343728
35BMX1.32260614
36CAMK1G1.31613548
37TTK1.31570675
38CAMK1D1.31022372
39NTRK11.27316912
40BRD41.25763232
41MAP3K81.21523272
42SRPK11.17692013
43TAOK11.15427914
44FGFR41.11095672
45LRRK21.09800773
46CHEK11.08602095
47PRKD31.06613158
48PDGFRA1.06285901
49TSSK61.06165229
50WEE11.05393917
51PAK21.02747413
52RPS6KA41.01918661
53MET0.99500031
54PNCK0.98465583
55EPHA20.94452578
56CDK70.94185770
57JAK30.93800228
58MAPKAPK30.93004762
59FLT30.92896215
60MAP2K30.91435289
61VRK20.91425830
62PASK0.90723084
63PAK40.88607700
64TESK10.88529046
65ATR0.88348350
66LATS20.86215692
67BRSK10.81698296
68PIM10.81600335
69ZAP700.80614056
70FGFR30.75525005
71ATM0.74592846
72* CDK20.72834007
73DMPK0.72600682
74FGFR10.72309838
75STK40.71910189
76KSR20.68989844
77GRK60.68837099
78WNK10.68629122
79AURKB0.67522931
80ERBB40.67041003
81CHUK0.65712358
82PLK10.64728411
83MAP3K70.64584569
84NME20.63413354
85TYRO30.62424098
86PDGFRB0.60151343
87MKNK10.59704511
88EPHB10.59431091
89CLK10.58444669
90FGFR20.58358271
91MKNK20.55899235
92PTK20.55773611
93BRAF0.55595119
94RPS6KA10.54488722
95MAP3K130.54332501
96CHEK20.53439381
97EIF2AK20.52360506
98CSNK1E0.51532533
99MAPK110.50890786
100MAPK100.50337572
101HIPK20.49563501
102TYK20.49061589
103SGK30.48458567
104CSNK1D0.48369060
105MARK20.47725322
106PBK0.47041231
107CDC42BPA0.46415237
108AKT20.45162925
109SIK20.45099345
110CDK10.44803357
111CDK90.44308190
112GSK3B0.44236720
113JAK20.43130877
114RET0.43077897
115AURKA0.41840050
116MAP3K30.41585539
117CSK0.40544391
118MAP3K110.40444826
119MAPK140.39359213
120LMTK20.38147057
121RPS6KB10.38124657
122PRKDC0.38017967
123BRSK20.36957811
124MELK0.36878464
125MAP3K50.36672778
126EGFR0.36369496
127JAK10.35623865
128* MAPK10.34857351
129PAK10.34815142
130TESK20.34265047
131PDK20.34068440
132RPS6KA20.33949314
133PLK30.32815403
134TRPM70.32254713

Predicted pathways (KEGG)

RankGene SetZ-score
1One carbon pool by folate_Homo sapiens_hsa006703.06990060
2RNA transport_Homo sapiens_hsa030132.40695484
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.37374460
4Nitrogen metabolism_Homo sapiens_hsa009102.17944739
5Lysine degradation_Homo sapiens_hsa003101.95054323
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.90662447
7mRNA surveillance pathway_Homo sapiens_hsa030151.86024982
8Selenocompound metabolism_Homo sapiens_hsa004501.83537553
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.78996073
10Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.70832306
11Chronic myeloid leukemia_Homo sapiens_hsa052201.66368086
12Cell cycle_Homo sapiens_hsa041101.54707295
13DNA replication_Homo sapiens_hsa030301.53576216
14Non-homologous end-joining_Homo sapiens_hsa034501.52459252
15mTOR signaling pathway_Homo sapiens_hsa041501.51440318
16Biosynthesis of amino acids_Homo sapiens_hsa012301.49666765
17Spliceosome_Homo sapiens_hsa030401.45827050
18Central carbon metabolism in cancer_Homo sapiens_hsa052301.43745986
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37263470
20Arginine biosynthesis_Homo sapiens_hsa002201.35646460
21Acute myeloid leukemia_Homo sapiens_hsa052211.35166976
22Antigen processing and presentation_Homo sapiens_hsa046121.34137479
23Cyanoamino acid metabolism_Homo sapiens_hsa004601.32728144
24Small cell lung cancer_Homo sapiens_hsa052221.29732705
25MicroRNAs in cancer_Homo sapiens_hsa052061.27069886
26Viral carcinogenesis_Homo sapiens_hsa052031.25410267
27Mismatch repair_Homo sapiens_hsa034301.20772769
28Adherens junction_Homo sapiens_hsa045201.10177640
29Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.09470321
30ErbB signaling pathway_Homo sapiens_hsa040121.09416490
31Viral myocarditis_Homo sapiens_hsa054161.08498333
32Insulin resistance_Homo sapiens_hsa049311.08459259
33Notch signaling pathway_Homo sapiens_hsa043301.07511620
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.07023504
35HTLV-I infection_Homo sapiens_hsa051661.06544067
36Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.02826766
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.01784917
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.00829331
39Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.00505857
40Dorso-ventral axis formation_Homo sapiens_hsa043201.00210616
41Carbon metabolism_Homo sapiens_hsa012000.97784128
42Bladder cancer_Homo sapiens_hsa052190.96868179
43Nucleotide excision repair_Homo sapiens_hsa034200.96468667
44Herpes simplex infection_Homo sapiens_hsa051680.95870312
45Thyroid cancer_Homo sapiens_hsa052160.95614198
46Thyroid hormone signaling pathway_Homo sapiens_hsa049190.93145987
47Non-small cell lung cancer_Homo sapiens_hsa052230.92889014
48p53 signaling pathway_Homo sapiens_hsa041150.90995143
49Fatty acid biosynthesis_Homo sapiens_hsa000610.90802741
50Pentose phosphate pathway_Homo sapiens_hsa000300.90685436
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.90188355
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.89608041
53Tight junction_Homo sapiens_hsa045300.88739848
54Long-term potentiation_Homo sapiens_hsa047200.88374780
55Adipocytokine signaling pathway_Homo sapiens_hsa049200.87917028
56Proteoglycans in cancer_Homo sapiens_hsa052050.87658726
57Base excision repair_Homo sapiens_hsa034100.86567025
58Wnt signaling pathway_Homo sapiens_hsa043100.86536427
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.86481767
60Endometrial cancer_Homo sapiens_hsa052130.84867303
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84829674
62Estrogen signaling pathway_Homo sapiens_hsa049150.84601564
63AMPK signaling pathway_Homo sapiens_hsa041520.84582127
64Thyroid hormone synthesis_Homo sapiens_hsa049180.84268851
65Glucagon signaling pathway_Homo sapiens_hsa049220.82083058
66Vitamin B6 metabolism_Homo sapiens_hsa007500.81929331
67Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81597009
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81093608
69Toxoplasmosis_Homo sapiens_hsa051450.80783437
70Inositol phosphate metabolism_Homo sapiens_hsa005620.80661983
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80660282
72HIF-1 signaling pathway_Homo sapiens_hsa040660.80331185
73Measles_Homo sapiens_hsa051620.80027647
74B cell receptor signaling pathway_Homo sapiens_hsa046620.79770891
75Prostate cancer_Homo sapiens_hsa052150.79538571
76Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.79243374
77T cell receptor signaling pathway_Homo sapiens_hsa046600.79232162
78Melanoma_Homo sapiens_hsa052180.78940082
79Legionellosis_Homo sapiens_hsa051340.78418183
80Hepatitis B_Homo sapiens_hsa051610.77188371
81N-Glycan biosynthesis_Homo sapiens_hsa005100.76406705
82Epstein-Barr virus infection_Homo sapiens_hsa051690.76022883
83Pancreatic cancer_Homo sapiens_hsa052120.75944143
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.75634301
85Fat digestion and absorption_Homo sapiens_hsa049750.75086318
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74330211
87Insulin signaling pathway_Homo sapiens_hsa049100.74007734
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.71947231
89Apoptosis_Homo sapiens_hsa042100.71908849
90Prion diseases_Homo sapiens_hsa050200.71848717
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.71135313
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69616355
93Pyruvate metabolism_Homo sapiens_hsa006200.69496036
94Melanogenesis_Homo sapiens_hsa049160.68300397
95Influenza A_Homo sapiens_hsa051640.68056334
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67822858
97Prolactin signaling pathway_Homo sapiens_hsa049170.67611184
98ECM-receptor interaction_Homo sapiens_hsa045120.66191293
99Transcriptional misregulation in cancer_Homo sapiens_hsa052020.65893031
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.64337047
101Colorectal cancer_Homo sapiens_hsa052100.64107497
102Hippo signaling pathway_Homo sapiens_hsa043900.63297167
103RNA degradation_Homo sapiens_hsa030180.63202671
104VEGF signaling pathway_Homo sapiens_hsa043700.61647986
105AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59118315
106Glioma_Homo sapiens_hsa052140.58958963
107Choline metabolism in cancer_Homo sapiens_hsa052310.56749703
108Focal adhesion_Homo sapiens_hsa045100.56731400
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.54407664
110Osteoclast differentiation_Homo sapiens_hsa043800.53613620
111Type II diabetes mellitus_Homo sapiens_hsa049300.53396023
112Galactose metabolism_Homo sapiens_hsa000520.52698745
113Pathways in cancer_Homo sapiens_hsa052000.52264220
114TGF-beta signaling pathway_Homo sapiens_hsa043500.52194644
115Drug metabolism - other enzymes_Homo sapiens_hsa009830.51746675
116Renal cell carcinoma_Homo sapiens_hsa052110.50378164
117GnRH signaling pathway_Homo sapiens_hsa049120.50323921
118Gap junction_Homo sapiens_hsa045400.49793287
119Oocyte meiosis_Homo sapiens_hsa041140.49753247
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.49562333
121Fructose and mannose metabolism_Homo sapiens_hsa000510.49418616
122PPAR signaling pathway_Homo sapiens_hsa033200.49406358
123Basal cell carcinoma_Homo sapiens_hsa052170.49334116
124Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49051291
125Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47381230
126Amoebiasis_Homo sapiens_hsa051460.47148043
127Leishmaniasis_Homo sapiens_hsa051400.46905134
128FoxO signaling pathway_Homo sapiens_hsa040680.46762478
129Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.46267147
130Pyrimidine metabolism_Homo sapiens_hsa002400.45654699
131Phospholipase D signaling pathway_Homo sapiens_hsa040720.45618921
132Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45173414

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