

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sulfate transmembrane transport (GO:1902358) | 6.80558326 |
| 2 | sterol catabolic process (GO:0016127) | 6.49727474 |
| 3 | cholesterol catabolic process (GO:0006707) | 6.49727474 |
| 4 | cerebral cortex radially oriented cell migration (GO:0021799) | 6.23693538 |
| 5 | mRNA modification (GO:0016556) | 6.01512821 |
| 6 | sulfate transport (GO:0008272) | 5.79900737 |
| 7 | acrosome assembly (GO:0001675) | 5.64387156 |
| 8 | cytidine deamination (GO:0009972) | 5.13934694 |
| 9 | cytidine metabolic process (GO:0046087) | 5.13934694 |
| 10 | cytidine catabolic process (GO:0006216) | 5.13934694 |
| 11 | entrainment of circadian clock by photoperiod (GO:0043153) | 5.09497061 |
| 12 | melanocyte differentiation (GO:0030318) | 5.05973722 |
| 13 | regulation of cholesterol homeostasis (GO:2000188) | 5.05797181 |
| 14 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 4.97440510 |
| 15 | entrainment of circadian clock (GO:0009649) | 4.92770660 |
| 16 | protein polyglutamylation (GO:0018095) | 4.78492316 |
| 17 | pigment cell differentiation (GO:0050931) | 4.58800069 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.48294617 |
| 19 | virion assembly (GO:0019068) | 4.45812300 |
| 20 | lipoprotein transport (GO:0042953) | 4.43257032 |
| 21 | tRNA methylation (GO:0030488) | 4.39215178 |
| 22 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 4.32731736 |
| 23 | mucosal-associated lymphoid tissue development (GO:0048537) | 4.25014153 |
| 24 | Peyers patch development (GO:0048541) | 4.25014153 |
| 25 | regulation of megakaryocyte differentiation (GO:0045652) | 4.23216812 |
| 26 | regulation of synapse maturation (GO:0090128) | 4.19348727 |
| 27 | viral protein processing (GO:0019082) | 4.17458934 |
| 28 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 4.09445577 |
| 29 | COPII vesicle coating (GO:0048208) | 4.07651862 |
| 30 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 4.05565747 |
| 31 | positive regulation of extracellular matrix organization (GO:1903055) | 3.99050486 |
| 32 | detection of light stimulus involved in visual perception (GO:0050908) | 3.96883898 |
| 33 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.96883898 |
| 34 | keratinocyte development (GO:0003334) | 3.95960323 |
| 35 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.95770645 |
| 36 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.95770645 |
| 37 | TOR signaling (GO:0031929) | 3.95239138 |
| 38 | photoperiodism (GO:0009648) | 3.86880139 |
| 39 | somite development (GO:0061053) | 3.83757518 |
| 40 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.83025810 |
| 41 | positive regulation of astrocyte differentiation (GO:0048711) | 3.74583000 |
| 42 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 3.74420624 |
| 43 | positive regulation of erythrocyte differentiation (GO:0045648) | 3.73730318 |
| 44 | base-excision repair, AP site formation (GO:0006285) | 3.71604000 |
| 45 | mammary gland epithelial cell proliferation (GO:0033598) | 3.69553408 |
| 46 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.69269639 |
| 47 | positive regulation of action potential (GO:0045760) | 3.64367059 |
| 48 | base-excision repair (GO:0006284) | 3.63694154 |
| 49 | mitochondrial calcium ion homeostasis (GO:0051560) | 3.62420780 |
| 50 | DNA demethylation (GO:0080111) | 3.54278092 |
| 51 | mitochondrial genome maintenance (GO:0000002) | 3.52848832 |
| 52 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 3.46237493 |
| 53 | stress granule assembly (GO:0034063) | 3.45457501 |
| 54 | response to nerve growth factor (GO:1990089) | 3.44946518 |
| 55 | cellular response to nerve growth factor stimulus (GO:1990090) | 3.44946518 |
| 56 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.44613976 |
| 57 | protein K6-linked ubiquitination (GO:0085020) | 3.44530899 |
| 58 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.44046075 |
| 59 | embryonic digestive tract morphogenesis (GO:0048557) | 3.40904935 |
| 60 | neuroepithelial cell differentiation (GO:0060563) | 3.36997584 |
| 61 | positive regulation of stem cell differentiation (GO:2000738) | 3.36832575 |
| 62 | negative regulation of stress fiber assembly (GO:0051497) | 3.33433242 |
| 63 | steroid catabolic process (GO:0006706) | 3.32672611 |
| 64 | negative regulation of dendrite development (GO:2000171) | 3.31267055 |
| 65 | regulation of gene silencing (GO:0060968) | 3.29099465 |
| 66 | mitochondrial DNA metabolic process (GO:0032042) | 3.25757646 |
| 67 | mitochondrial DNA replication (GO:0006264) | 3.25038925 |
| 68 | positive regulation of neuroblast proliferation (GO:0002052) | 3.25019052 |
| 69 | long term synaptic depression (GO:0060292) | 3.23737586 |
| 70 | regulation of metalloenzyme activity (GO:0048552) | 3.22909429 |
| 71 | ear development (GO:0043583) | 3.12162187 |
| 72 | positive regulation of protein homooligomerization (GO:0032464) | 3.10378827 |
| 73 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.09346614 |
| 74 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:2 | 3.08639436 |
| 75 | negative regulation of gene silencing (GO:0060969) | 3.06177658 |
| 76 | adult feeding behavior (GO:0008343) | 3.05170642 |
| 77 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.04856538 |
| 78 | regulation of hematopoietic progenitor cell differentiation (GO:1901532) | 3.03606906 |
| 79 | fibroblast migration (GO:0010761) | 3.01635983 |
| 80 | dopamine transport (GO:0015872) | 2.98204548 |
| 81 | establishment of protein localization to Golgi (GO:0072600) | 2.97796976 |
| 82 | cellular response to reactive nitrogen species (GO:1902170) | 2.96715880 |
| 83 | sulfur compound transport (GO:0072348) | 2.95349696 |
| 84 | positive regulation of histone deacetylation (GO:0031065) | 2.94434329 |
| 85 | positive regulation of megakaryocyte differentiation (GO:0045654) | 2.93686364 |
| 86 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.93001021 |
| 87 | negative regulation of mRNA processing (GO:0050686) | 2.90547247 |
| 88 | regulation of cilium movement (GO:0003352) | 2.90513559 |
| 89 | regulation of histone deacetylation (GO:0031063) | 2.86161849 |
| 90 | cell proliferation in forebrain (GO:0021846) | 2.86034137 |
| 91 | positive regulation of calcium ion import (GO:0090280) | 2.83301707 |
| 92 | response to gravity (GO:0009629) | 2.82643469 |
| 93 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.79848570 |
| 94 | natural killer cell differentiation (GO:0001779) | 2.78606109 |
| 95 | histone deubiquitination (GO:0016578) | 2.78179097 |
| 96 | negative regulation of DNA recombination (GO:0045910) | 2.76508815 |
| 97 | mRNA splice site selection (GO:0006376) | 2.75741090 |
| 98 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 2.75006224 |
| 99 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 2.75006224 |
| 100 | hematopoietic stem cell differentiation (GO:0060218) | 12.0278066 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 7.46483739 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 7.24082392 |
| 3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 5.01935423 |
| 4 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 4.16034382 |
| 5 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 3.56397180 |
| 6 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.41396150 |
| 7 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 3.15025413 |
| 8 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 3.15025413 |
| 9 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 3.15025413 |
| 10 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 3.05134668 |
| 11 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.63731363 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.62755891 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.50006177 |
| 14 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 2.39042966 |
| 15 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 11.1677606 |
| 16 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.87057955 |
| 17 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.65786318 |
| 18 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.49290788 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.46074728 |
| 20 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.36073058 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.32652659 |
| 22 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.32290739 |
| 23 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.31389164 |
| 24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.29459346 |
| 25 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27749272 |
| 26 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.25401956 |
| 27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.24320786 |
| 28 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.23371316 |
| 29 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.22810170 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.19184407 |
| 31 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.17362330 |
| 32 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.13812897 |
| 33 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.13216214 |
| 34 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.10616147 |
| 35 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.07502339 |
| 36 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05886769 |
| 37 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.04636253 |
| 38 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.02307861 |
| 39 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.02065561 |
| 40 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00754797 |
| 41 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.97806588 |
| 42 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96935787 |
| 43 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94662090 |
| 44 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.92895486 |
| 45 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.92468091 |
| 46 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.91071141 |
| 47 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.89910910 |
| 48 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.89081706 |
| 49 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88262048 |
| 50 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.87560360 |
| 51 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.87485452 |
| 52 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.87434963 |
| 53 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.86524591 |
| 54 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.85562339 |
| 55 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.85453776 |
| 56 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.85201595 |
| 57 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.85019375 |
| 58 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.84247474 |
| 59 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.82374283 |
| 60 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.82016752 |
| 61 | MYC_22102868_ChIP-Seq_BL_Human | 0.80013122 |
| 62 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.79807192 |
| 63 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.79256511 |
| 64 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.78574506 |
| 65 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.78041261 |
| 66 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.76468782 |
| 67 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.75467841 |
| 68 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.74611457 |
| 69 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.72554970 |
| 70 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.72430084 |
| 71 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.72178199 |
| 72 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.71484531 |
| 73 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.69196199 |
| 74 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.68259757 |
| 75 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.67087955 |
| 76 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.65680934 |
| 77 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.65172427 |
| 78 | STAT3_23295773_ChIP-Seq_U87_Human | 0.64529703 |
| 79 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.64449064 |
| 80 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.64433155 |
| 81 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.63876371 |
| 82 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.63828841 |
| 83 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.61766563 |
| 84 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.61760630 |
| 85 | P300_19829295_ChIP-Seq_ESCs_Human | 0.61502328 |
| 86 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.61442017 |
| 87 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.60502118 |
| 88 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.59529576 |
| 89 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.59469921 |
| 90 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.59259191 |
| 91 | JUN_21703547_ChIP-Seq_K562_Human | 0.59103375 |
| 92 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.58781464 |
| 93 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.58729818 |
| 94 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.58604696 |
| 95 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.57840652 |
| 96 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.57390056 |
| 97 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.56329145 |
| 98 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.56100237 |
| 99 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.56048689 |
| 100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.56048689 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008004_abnormal_stomach_pH | 9.44716949 |
| 2 | MP0000003_abnormal_adipose_tissue | 6.08162960 |
| 3 | MP0001502_abnormal_circadian_rhythm | 3.07386219 |
| 4 | MP0002933_joint_inflammation | 2.74920624 |
| 5 | MP0008961_abnormal_basal_metabolism | 2.55743371 |
| 6 | MP0005375_adipose_tissue_phenotype | 2.41353425 |
| 7 | MP0003195_calcinosis | 2.22525060 |
| 8 | MP0001986_abnormal_taste_sensitivity | 2.07671673 |
| 9 | MP0000371_diluted_coat_color | 2.02162435 |
| 10 | MP0000013_abnormal_adipose_tissue | 10.2034706 |
| 11 | MP0005076_abnormal_cell_differentiation | 1.86759585 |
| 12 | MP0008260_abnormal_autophagy | 1.82533586 |
| 13 | MP0009278_abnormal_bone_marrow | 1.78593407 |
| 14 | MP0001984_abnormal_olfaction | 1.70944330 |
| 15 | MP0004233_abnormal_muscle_weight | 1.69139645 |
| 16 | MP0002736_abnormal_nociception_after | 1.58249626 |
| 17 | MP0009250_abnormal_appendicular_skeleto | 1.54609974 |
| 18 | MP0002138_abnormal_hepatobiliary_system | 1.49229111 |
| 19 | MP0004484_altered_response_of | 1.40790145 |
| 20 | MP0010307_abnormal_tumor_latency | 1.40719608 |
| 21 | MP0003221_abnormal_cardiomyocyte_apopto | 1.35694504 |
| 22 | MP0001968_abnormal_touch/_nociception | 1.34419701 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.33159686 |
| 24 | MP0000470_abnormal_stomach_morphology | 1.30093603 |
| 25 | MP0008875_abnormal_xenobiotic_pharmacok | 1.27734402 |
| 26 | MP0004885_abnormal_endolymph | 1.25233737 |
| 27 | MP0002896_abnormal_bone_mineralization | 1.23028854 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.14231339 |
| 29 | MP0006054_spinal_hemorrhage | 1.12996088 |
| 30 | MP0000516_abnormal_urinary_system | 1.11966615 |
| 31 | MP0005367_renal/urinary_system_phenotyp | 1.11966615 |
| 32 | MP0002166_altered_tumor_susceptibility | 1.06736196 |
| 33 | MP0009115_abnormal_fat_cell | 1.06410474 |
| 34 | MP0003959_abnormal_lean_body | 1.06350179 |
| 35 | MP0001501_abnormal_sleep_pattern | 1.06221939 |
| 36 | MP0004742_abnormal_vestibular_system | 1.05749984 |
| 37 | MP0005410_abnormal_fertilization | 1.05188595 |
| 38 | MP0002282_abnormal_trachea_morphology | 1.03855541 |
| 39 | MP0003786_premature_aging | 1.01285152 |
| 40 | MP0008995_early_reproductive_senescence | 0.99999529 |
| 41 | MP0004808_abnormal_hematopoietic_stem | 0.96616429 |
| 42 | MP0010329_abnormal_lipoprotein_level | 0.95235499 |
| 43 | MP0000538_abnormal_urinary_bladder | 0.93197600 |
| 44 | MP0004147_increased_porphyrin_level | 0.91583267 |
| 45 | MP0005334_abnormal_fat_pad | 0.89760829 |
| 46 | MP0001929_abnormal_gametogenesis | 0.88094029 |
| 47 | MP0003172_abnormal_lysosome_physiology | 0.85253675 |
| 48 | MP0005360_urolithiasis | 0.82858660 |
| 49 | MP0002210_abnormal_sex_determination | 0.81417007 |
| 50 | MP0000627_abnormal_mammary_gland | 0.81242913 |
| 51 | MP0005452_abnormal_adipose_tissue | 0.80210412 |
| 52 | MP0003698_abnormal_male_reproductive | 0.79846875 |
| 53 | MP0004145_abnormal_muscle_electrophysio | 0.79283937 |
| 54 | MP0003948_abnormal_gas_homeostasis | 0.77828338 |
| 55 | MP0001545_abnormal_hematopoietic_system | 0.77006490 |
| 56 | MP0005397_hematopoietic_system_phenotyp | 0.77006490 |
| 57 | MP0000767_abnormal_smooth_muscle | 0.75640029 |
| 58 | MP0005253_abnormal_eye_physiology | 0.74836144 |
| 59 | MP0001186_pigmentation_phenotype | 0.74764068 |
| 60 | MP0001664_abnormal_digestion | 0.74154323 |
| 61 | MP0001944_abnormal_pancreas_morphology | 0.73915592 |
| 62 | MP0002075_abnormal_coat/hair_pigmentati | 0.72716377 |
| 63 | MP0002733_abnormal_thermal_nociception | 0.72153070 |
| 64 | MP0001485_abnormal_pinna_reflex | 0.71013479 |
| 65 | MP0002006_tumorigenesis | 0.70358628 |
| 66 | MP0002118_abnormal_lipid_homeostasis | 0.67871608 |
| 67 | MP0001145_abnormal_male_reproductive | 0.66743623 |
| 68 | MP0001764_abnormal_homeostasis | 0.64148709 |
| 69 | MP0009384_cardiac_valve_regurgitation | 0.63709849 |
| 70 | MP0004858_abnormal_nervous_system | 0.63298911 |
| 71 | MP0004142_abnormal_muscle_tone | 0.61392539 |
| 72 | MP0003011_delayed_dark_adaptation | 0.60606541 |
| 73 | MP0000653_abnormal_sex_gland | 0.60528015 |
| 74 | MP0002653_abnormal_ependyma_morphology | 0.59935995 |
| 75 | MP0003077_abnormal_cell_cycle | 0.59829396 |
| 76 | MP0002572_abnormal_emotion/affect_behav | 0.59525535 |
| 77 | MP0004019_abnormal_vitamin_homeostasis | 0.58595004 |
| 78 | MP0002751_abnormal_autonomic_nervous | 0.57890902 |
| 79 | MP0005075_abnormal_melanosome_morpholog | 0.56343096 |
| 80 | MP0008770_decreased_survivor_rate | 0.55764841 |
| 81 | MP0002970_abnormal_white_adipose | 0.54429541 |
| 82 | MP0005332_abnormal_amino_acid | 0.53950600 |
| 83 | MP0000613_abnormal_salivary_gland | 0.53181317 |
| 84 | MP0006072_abnormal_retinal_apoptosis | 0.52759940 |
| 85 | MP0000609_abnormal_liver_physiology | 0.52507652 |
| 86 | MP0003724_increased_susceptibility_to | 0.51973568 |
| 87 | MP0002161_abnormal_fertility/fecundity | 0.51041977 |
| 88 | MP0001486_abnormal_startle_reflex | 0.49724830 |
| 89 | MP0004264_abnormal_extraembryonic_tissu | 0.48720187 |
| 90 | MP0002078_abnormal_glucose_homeostasis | 0.47520477 |
| 91 | MP0002135_abnormal_kidney_morphology | 0.46751888 |
| 92 | MP0009931_abnormal_skin_appearance | 0.46611612 |
| 93 | MP0002928_abnormal_bile_duct | 0.45217709 |
| 94 | MP0010368_abnormal_lymphatic_system | 0.44545534 |
| 95 | MP0001943_abnormal_respiration | 0.43200628 |
| 96 | MP0003953_abnormal_hormone_level | 0.43091899 |
| 97 | MP0003879_abnormal_hair_cell | 0.42803138 |
| 98 | MP0000427_abnormal_hair_cycle | 0.42654448 |
| 99 | MP0002229_neurodegeneration | 0.41984595 |
| 100 | MP0003635_abnormal_synaptic_transmissio | 0.40097095 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Generalized hypopigmentation of hair (HP:0011358) | 6.62510032 |
| 2 | Hypoplasia of the fovea (HP:0007750) | 6.27479738 |
| 3 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 6.27479738 |
| 4 | Anterior segment dysgenesis (HP:0007700) | 5.11019436 |
| 5 | Prominent supraorbital ridges (HP:0000336) | 4.80832486 |
| 6 | Abnormality of the fovea (HP:0000493) | 4.80772530 |
| 7 | Curly hair (HP:0002212) | 4.72594167 |
| 8 | Abnormality of the renal cortex (HP:0011035) | 4.66448695 |
| 9 | Renal cortical cysts (HP:0000803) | 4.61551506 |
| 10 | Aplasia/Hypoplasia of the macula (HP:0008059) | 4.07549867 |
| 11 | Proximal amyotrophy (HP:0007126) | 3.95511515 |
| 12 | Wormian bones (HP:0002645) | 3.90131908 |
| 13 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 3.75480824 |
| 14 | Generalized hypopigmentation (HP:0007513) | 3.75420394 |
| 15 | Flat capital femoral epiphysis (HP:0003370) | 3.75102833 |
| 16 | Ocular albinism (HP:0001107) | 3.62930274 |
| 17 | Metaphyseal irregularity (HP:0003025) | 3.54990034 |
| 18 | Thrombocytosis (HP:0001894) | 3.52492363 |
| 19 | Cone-rod dystrophy (HP:0000548) | 3.46202936 |
| 20 | Vertebral arch anomaly (HP:0008438) | 3.45312199 |
| 21 | Abnormal albumin level (HP:0012116) | 3.44319752 |
| 22 | Hypoalbuminemia (HP:0003073) | 3.44319752 |
| 23 | Abnormality of methionine metabolism (HP:0010901) | 3.38781754 |
| 24 | Abnormal hair laboratory examination (HP:0003328) | 3.37482234 |
| 25 | Absent speech (HP:0001344) | 3.25216081 |
| 26 | Small epiphyses (HP:0010585) | 3.24505122 |
| 27 | Cholecystitis (HP:0001082) | 3.24039881 |
| 28 | Abnormal gallbladder physiology (HP:0012438) | 3.24039881 |
| 29 | Prominent forehead (HP:0011220) | 3.21769705 |
| 30 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 3.17046080 |
| 31 | Abnormality of small intestinal villus morphology (HP:0011472) | 3.09062091 |
| 32 | Villous atrophy (HP:0011473) | 3.09062091 |
| 33 | Iris hypopigmentation (HP:0007730) | 3.07169380 |
| 34 | Increased mean platelet volume (HP:0011877) | 3.03073480 |
| 35 | Hypoplastic labia majora (HP:0000059) | 2.98916129 |
| 36 | Delayed epiphyseal ossification (HP:0002663) | 2.96763571 |
| 37 | Carpal bone hypoplasia (HP:0001498) | 2.86714793 |
| 38 | Abnormality of the labia majora (HP:0012881) | 2.82473708 |
| 39 | Tracheomalacia (HP:0002779) | 2.81069181 |
| 40 | Vacuolated lymphocytes (HP:0001922) | 2.80930151 |
| 41 | Abnormal platelet volume (HP:0011876) | 2.80089590 |
| 42 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.77461593 |
| 43 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.76086237 |
| 44 | Nausea (HP:0002018) | 2.71756524 |
| 45 | Severe visual impairment (HP:0001141) | 2.68050456 |
| 46 | J-shaped sella turcica (HP:0002680) | 2.67921065 |
| 47 | Polyuria (HP:0000103) | 2.65399201 |
| 48 | Irregular epiphyses (HP:0010582) | 2.65279091 |
| 49 | Hyperaldosteronism (HP:0000859) | 2.61590299 |
| 50 | Scrotal hypoplasia (HP:0000046) | 2.58128921 |
| 51 | Aortic regurgitation (HP:0001659) | 2.56538057 |
| 52 | Chronic hepatic failure (HP:0100626) | 2.54577902 |
| 53 | Glossoptosis (HP:0000162) | 2.54170802 |
| 54 | Chorioretinal coloboma (HP:0000567) | 2.54045365 |
| 55 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.45852250 |
| 56 | Abnormality of iron homeostasis (HP:0011031) | 2.45386421 |
| 57 | Progressive external ophthalmoplegia (HP:0000590) | 2.43180320 |
| 58 | Stomach cancer (HP:0012126) | 2.39904323 |
| 59 | Abnormality of macular pigmentation (HP:0008002) | 2.38360984 |
| 60 | Woolly hair (HP:0002224) | 2.33938785 |
| 61 | Broad distal phalanx of finger (HP:0009836) | 2.33054407 |
| 62 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.28902170 |
| 63 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.26094392 |
| 64 | Absent epiphyses (HP:0010577) | 2.22326658 |
| 65 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.22326658 |
| 66 | Narrow mouth (HP:0000160) | 2.21524255 |
| 67 | Esotropia (HP:0000565) | 2.16887726 |
| 68 | Abnormal urine output (HP:0012590) | 2.16848725 |
| 69 | Abnormality of chloride homeostasis (HP:0011422) | 2.15540659 |
| 70 | Flattened epiphyses (HP:0003071) | 2.15390419 |
| 71 | Brittle hair (HP:0002299) | 2.14862872 |
| 72 | Low anterior hairline (HP:0000294) | 2.14411277 |
| 73 | Ependymoma (HP:0002888) | 2.12781856 |
| 74 | Tubulointerstitial fibrosis (HP:0005576) | 2.12715200 |
| 75 | Conjugated hyperbilirubinemia (HP:0002908) | 2.12497580 |
| 76 | Increased corneal curvature (HP:0100692) | 2.07263034 |
| 77 | Keratoconus (HP:0000563) | 2.07263034 |
| 78 | Abnormality of the costochondral junction (HP:0000919) | 2.05142275 |
| 79 | Hypoplasia of the thymus (HP:0000778) | 2.04455086 |
| 80 | Metabolic alkalosis (HP:0200114) | 2.03908825 |
| 81 | Overlapping toe (HP:0001845) | 2.02252209 |
| 82 | Oligodactyly (hands) (HP:0001180) | 2.02157728 |
| 83 | Labial hypoplasia (HP:0000066) | 2.02067463 |
| 84 | Hypokalemic alkalosis (HP:0001949) | 2.01991920 |
| 85 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.99247114 |
| 86 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.98966233 |
| 87 | Polydipsia (HP:0001959) | 1.98736516 |
| 88 | Abnormal drinking behavior (HP:0030082) | 1.98736516 |
| 89 | Easy fatigability (HP:0003388) | 1.97541933 |
| 90 | Agnosia (HP:0010524) | 1.96247572 |
| 91 | Broad nasal tip (HP:0000455) | 1.95723308 |
| 92 | Abnormality of the renal medulla (HP:0100957) | 1.94658274 |
| 93 | Prominent nose (HP:0000448) | 1.93190700 |
| 94 | Congenital stationary night blindness (HP:0007642) | 1.91449793 |
| 95 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.91028479 |
| 96 | Tetraplegia (HP:0002445) | 1.88170029 |
| 97 | Rib fusion (HP:0000902) | 1.87887220 |
| 98 | Gaze-evoked nystagmus (HP:0000640) | 1.87322308 |
| 99 | Optic nerve hypoplasia (HP:0000609) | 1.86123691 |
| 100 | Pectus carinatum (HP:0000768) | 1.85352823 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 8.72387080 |
| 2 | ZAK | 7.12061489 |
| 3 | CASK | 6.81552407 |
| 4 | CCNB1 | 2.86362882 |
| 5 | MST4 | 2.83242987 |
| 6 | CDK12 | 2.65308349 |
| 7 | VRK1 | 2.13614081 |
| 8 | TSSK6 | 2.12508062 |
| 9 | BCKDK | 1.91679602 |
| 10 | PHKG1 | 1.91380981 |
| 11 | PHKG2 | 1.91380981 |
| 12 | DAPK2 | 1.76286304 |
| 13 | KDR | 1.67357601 |
| 14 | FRK | 1.64085399 |
| 15 | FLT3 | 1.61237060 |
| 16 | WNK4 | 1.59363809 |
| 17 | STK38L | 1.32072287 |
| 18 | PIM1 | 1.17519473 |
| 19 | RPS6KA5 | 1.15621886 |
| 20 | PKN1 | 1.10880962 |
| 21 | WEE1 | 1.10620869 |
| 22 | STK24 | 1.08870450 |
| 23 | MAP3K5 | 1.08044514 |
| 24 | SIK3 | 1.06503434 |
| 25 | PRKCI | 0.94094475 |
| 26 | BMX | 0.87319958 |
| 27 | NEK6 | 0.86186670 |
| 28 | ICK | 0.83634481 |
| 29 | DAPK1 | 0.83154388 |
| 30 | MELK | 0.79948224 |
| 31 | TAOK3 | 0.79694479 |
| 32 | MKNK2 | 0.78552920 |
| 33 | PAK3 | 0.77975495 |
| 34 | PRKAA1 | 0.75347185 |
| 35 | JAK2 | 0.74214250 |
| 36 | NTRK1 | 0.72038078 |
| 37 | KSR1 | 0.69217647 |
| 38 | PRKCQ | 0.69053978 |
| 39 | STK39 | 0.68147075 |
| 40 | AKT2 | 0.66429601 |
| 41 | JAK3 | 0.64007156 |
| 42 | EPHA2 | 0.61523555 |
| 43 | PNCK | 0.61168828 |
| 44 | KSR2 | 0.59853885 |
| 45 | ROCK1 | 0.53957136 |
| 46 | CHUK | 0.51187944 |
| 47 | CDK6 | 0.50019211 |
| 48 | TNK2 | 0.49750453 |
| 49 | JAK1 | 0.47362153 |
| 50 | MET | 0.46157254 |
| 51 | STK4 | 0.46107239 |
| 52 | MAPK14 | 0.46007819 |
| 53 | MAPK10 | 0.45508424 |
| 54 | STK10 | 0.44425449 |
| 55 | CHEK2 | 0.43368548 |
| 56 | PRKAA2 | 0.42531017 |
| 57 | PIK3CA | 0.41466996 |
| 58 | MAPK9 | 0.39401301 |
| 59 | MAP3K14 | 0.37592951 |
| 60 | CDK7 | 0.37287757 |
| 61 | CAMK1G | 0.32496287 |
| 62 | MATK | 0.32495489 |
| 63 | TRIM28 | 0.31907861 |
| 64 | MAP3K8 | 0.31655769 |
| 65 | CDK4 | 0.30797413 |
| 66 | CSNK1G3 | 0.30140249 |
| 67 | AURKB | 0.29828044 |
| 68 | DAPK3 | 0.29626583 |
| 69 | WNK1 | 0.29563717 |
| 70 | IKBKB | 0.26353393 |
| 71 | GSK3B | 0.23959791 |
| 72 | CSNK1A1L | 0.23267619 |
| 73 | CDK2 | 0.22862381 |
| 74 | BMPR2 | 0.22470828 |
| 75 | PDK1 | 0.22375308 |
| 76 | PDPK1 | 0.22358666 |
| 77 | MAP4K2 | 0.21934811 |
| 78 | DYRK2 | 0.21829772 |
| 79 | CSNK1G1 | 0.21009034 |
| 80 | PINK1 | 0.20561908 |
| 81 | ADRBK2 | 0.20548079 |
| 82 | BMPR1B | 0.19112147 |
| 83 | ZAP70 | 0.17707676 |
| 84 | TGFBR2 | 0.17615072 |
| 85 | MAP3K1 | 0.15426891 |
| 86 | PAK6 | 0.14528780 |
| 87 | CDK1 | 0.14403107 |
| 88 | MAP2K1 | 0.14078024 |
| 89 | MAP3K6 | 0.13958409 |
| 90 | LRRK2 | 0.13307334 |
| 91 | MAPK11 | 0.12865468 |
| 92 | SGK1 | 0.12467339 |
| 93 | HIPK2 | 0.12200299 |
| 94 | AURKA | 0.11699587 |
| 95 | TEC | 0.10549800 |
| 96 | SIK2 | 0.10036693 |
| 97 | IKBKE | 0.09686654 |
| 98 | GRK1 | 0.08160995 |
| 99 | ADRBK1 | 0.07411698 |
| 100 | MAPK15 | 0.06597939 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Base excision repair_Homo sapiens_hsa03410 | 5.89174298 |
| 2 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 5.29576973 |
| 3 | Alcoholism_Homo sapiens_hsa05034 | 4.34328542 |
| 4 | Selenocompound metabolism_Homo sapiens_hsa00450 | 3.12534335 |
| 5 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.96362945 |
| 6 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 2.57416987 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.38808184 |
| 8 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.32145415 |
| 9 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.97386667 |
| 10 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.87191381 |
| 11 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.87049947 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.82449181 |
| 13 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.77818342 |
| 14 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.74152416 |
| 15 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.64358035 |
| 16 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.61069548 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.60852042 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.57926254 |
| 19 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.48891671 |
| 20 | Mineral absorption_Homo sapiens_hsa04978 | 1.44672102 |
| 21 | RNA polymerase_Homo sapiens_hsa03020 | 1.42456938 |
| 22 | Circadian rhythm_Homo sapiens_hsa04710 | 1.35405231 |
| 23 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.27504691 |
| 24 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.26332572 |
| 25 | Olfactory transduction_Homo sapiens_hsa04740 | 1.25848720 |
| 26 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.24730246 |
| 27 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.03908578 |
| 28 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.03488522 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.97787660 |
| 30 | Taste transduction_Homo sapiens_hsa04742 | 0.95563310 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 0.93478677 |
| 32 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.91842367 |
| 33 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.91724511 |
| 34 | Retinol metabolism_Homo sapiens_hsa00830 | 0.88535550 |
| 35 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.87796891 |
| 36 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.81554000 |
| 37 | Circadian entrainment_Homo sapiens_hsa04713 | 0.79916074 |
| 38 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.78699054 |
| 39 | Lysine degradation_Homo sapiens_hsa00310 | 0.77407693 |
| 40 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.77348032 |
| 41 | Salivary secretion_Homo sapiens_hsa04970 | 0.76975478 |
| 42 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.76103367 |
| 43 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.75881810 |
| 44 | ABC transporters_Homo sapiens_hsa02010 | 0.75736109 |
| 45 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.73078738 |
| 46 | Insulin secretion_Homo sapiens_hsa04911 | 0.70648590 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70149864 |
| 48 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.69917492 |
| 49 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.65559194 |
| 50 | Cocaine addiction_Homo sapiens_hsa05030 | 0.64859960 |
| 51 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.63554146 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62370235 |
| 53 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.61873493 |
| 54 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.60292167 |
| 55 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.60109564 |
| 56 | Nicotine addiction_Homo sapiens_hsa05033 | 0.57232571 |
| 57 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.56869889 |
| 58 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.56132258 |
| 59 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.55902372 |
| 60 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.55569266 |
| 61 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.54235115 |
| 62 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.53414802 |
| 63 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52554059 |
| 64 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.52411801 |
| 65 | Bile secretion_Homo sapiens_hsa04976 | 0.50637066 |
| 66 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.48987916 |
| 67 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.47970663 |
| 68 | Thyroid cancer_Homo sapiens_hsa05216 | 0.47879819 |
| 69 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.46965473 |
| 70 | Insulin resistance_Homo sapiens_hsa04931 | 0.45381148 |
| 71 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.45275799 |
| 72 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.45147517 |
| 73 | RNA degradation_Homo sapiens_hsa03018 | 0.41911740 |
| 74 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.40998153 |
| 75 | Morphine addiction_Homo sapiens_hsa05032 | 0.40200272 |
| 76 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.39186631 |
| 77 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.37020274 |
| 78 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.36099709 |
| 79 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.34519641 |
| 80 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.32610542 |
| 81 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.32469468 |
| 82 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32342134 |
| 83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.30191710 |
| 84 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.29041880 |
| 85 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.26866615 |
| 86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.25259373 |
| 87 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.25108158 |
| 88 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25072247 |
| 89 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.24262253 |
| 90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.23503748 |
| 91 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.23074247 |
| 92 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.22876932 |
| 93 | Endocytosis_Homo sapiens_hsa04144 | 0.22819555 |
| 94 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.21775911 |
| 95 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.21293434 |
| 96 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.20923753 |
| 97 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.20312342 |
| 98 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.19477202 |
| 99 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.18223329 |
| 100 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.18166713 |

