LAX1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)7.20102419
2antigen processing and presentation of endogenous antigen (GO:0019883)7.13667207
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)7.13139200
4antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)7.13139200
5positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.97817287
6regulation of B cell receptor signaling pathway (GO:0050855)5.94711084
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.88488338
8negative T cell selection (GO:0043383)5.79109200
9negative thymic T cell selection (GO:0045060)5.78867596
10regulation of gamma-delta T cell differentiation (GO:0045586)5.76798668
11B cell receptor signaling pathway (GO:0050853)5.59440477
12positive thymic T cell selection (GO:0045059)5.49939070
13cellular response to interleukin-15 (GO:0071350)5.38420152
14response to interleukin-15 (GO:0070672)5.36558724
15regulation of gamma-delta T cell activation (GO:0046643)5.30762639
16regulation of B cell differentiation (GO:0045577)4.98895227
17thymic T cell selection (GO:0045061)4.95500006
18regulation of isotype switching to IgG isotypes (GO:0048302)4.81820429
19regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.59962028
20positive T cell selection (GO:0043368)4.59619827
21T cell selection (GO:0045058)4.49831066
22leukocyte aggregation (GO:0070486)4.45066942
23negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.43936493
24negative regulation of cell killing (GO:0031342)4.43936493
25regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.41731329
26T cell migration (GO:0072678)4.37284838
27* antigen receptor-mediated signaling pathway (GO:0050851)4.26544569
28T cell costimulation (GO:0031295)4.24089222
29positive regulation of B cell differentiation (GO:0045579)4.19957211
30lymphocyte costimulation (GO:0031294)4.19793683
31interferon-gamma production (GO:0032609)4.19222676
32antigen processing and presentation via MHC class Ib (GO:0002475)4.07730329
33negative regulation of T cell mediated immunity (GO:0002710)4.07220432
34regulation of T cell receptor signaling pathway (GO:0050856)4.05543519
35T cell receptor signaling pathway (GO:0050852)4.05094505
36positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.04817420
37regulation of T cell tolerance induction (GO:0002664)3.97768537
38regulation of alpha-beta T cell proliferation (GO:0046640)3.92968971
39cellular response to zinc ion (GO:0071294)3.85537155
40negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.65596825
41positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.62285666
42mast cell activation (GO:0045576)3.61259578
43ribosomal small subunit assembly (GO:0000028)3.57785593
44T cell homeostasis (GO:0043029)3.56823270
45* immune response-activating cell surface receptor signaling pathway (GO:0002429)3.50810481
46mature B cell differentiation (GO:0002335)3.50692207
47regulation of natural killer cell mediated immunity (GO:0002715)3.50488038
48regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.50488038
49positive regulation of T cell mediated cytotoxicity (GO:0001916)3.50179118
50positive regulation of natural killer cell mediated immunity (GO:0002717)3.48366196
51positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.48366196
52positive regulation of immunoglobulin production (GO:0002639)3.47469906
53negative regulation of lymphocyte mediated immunity (GO:0002707)3.47313267
54regulation of type I interferon-mediated signaling pathway (GO:0060338)3.43966410
55response to type I interferon (GO:0034340)3.43148262
56regulation of interleukin-12 biosynthetic process (GO:0045075)3.42937965
57positive regulation of isotype switching (GO:0045830)3.41971261
58regulation of regulatory T cell differentiation (GO:0045589)3.39491561
59positive regulation of alpha-beta T cell proliferation (GO:0046641)3.39279758
60B cell proliferation (GO:0042100)3.37389506
61type I interferon signaling pathway (GO:0060337)3.37034915
62cellular response to type I interferon (GO:0071357)3.37034915
63tolerance induction (GO:0002507)3.35143976
64lymphocyte homeostasis (GO:0002260)3.33643288
65defense response to protozoan (GO:0042832)3.32875109
66positive regulation of interleukin-2 production (GO:0032743)3.27294407
67regulation of cell killing (GO:0031341)3.26034466
68interferon-gamma-mediated signaling pathway (GO:0060333)3.23305777
69regulation of B cell proliferation (GO:0030888)3.22046840
70positive regulation of tolerance induction (GO:0002645)3.21823935
71regulation of response to interferon-gamma (GO:0060330)3.21263965
72negative regulation of T cell receptor signaling pathway (GO:0050860)3.21117965
73NIK/NF-kappaB signaling (GO:0038061)3.20945135
74alpha-beta T cell differentiation (GO:0046632)3.19630870
75response to protozoan (GO:0001562)3.18814110
76viral transcription (GO:0019083)3.18766840
77regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.18582996
78positive regulation of defense response to virus by host (GO:0002230)3.15824810
79regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.15058285
80regulation of B cell mediated immunity (GO:0002712)3.12606959
81regulation of isotype switching (GO:0045191)3.12202570
82natural killer cell activation (GO:0030101)3.11468196
83negative regulation of B cell proliferation (GO:0030889)3.10955613
84negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.09769185
85positive regulation of cell killing (GO:0031343)3.09469723
86regulation of immunoglobulin production (GO:0002637)3.09322812
87DNA deamination (GO:0045006)3.08448831
88positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.05168761
89regulation of B cell activation (GO:0050864)3.04675915
90regulation of interleukin-2 biosynthetic process (GO:0045076)3.04132978
91regulation of leukocyte mediated cytotoxicity (GO:0001910)3.03565741
92regulation of immunoglobulin mediated immune response (GO:0002889)3.03068257
93CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.02978046
94leukocyte homeostasis (GO:0001776)3.01443217
95lymph node development (GO:0048535)2.99919656
96mast cell degranulation (GO:0043303)2.99473595
97mast cell activation involved in immune response (GO:0002279)2.99473595
98translational termination (GO:0006415)2.99417904
99alpha-beta T cell activation (GO:0046631)2.98531838
100immunoglobulin mediated immune response (GO:0016064)2.98072160
101negative regulation of adaptive immune response (GO:0002820)2.97515874
102regulation of alpha-beta T cell activation (GO:0046634)2.97437895
103positive regulation of DNA recombination (GO:0045911)2.97089679
104regulation of tolerance induction (GO:0002643)2.96286420
105T cell differentiation (GO:0030217)2.96164740
106mature B cell differentiation involved in immune response (GO:0002313)2.95790486
107megakaryocyte development (GO:0035855)2.95351957
108activated T cell proliferation (GO:0050798)2.95175561
109positive regulation of immunoglobulin mediated immune response (GO:0002891)2.92983608
110positive regulation of B cell mediated immunity (GO:0002714)2.92983608
111regulation of granulocyte differentiation (GO:0030852)2.91257511
112Arp2/3 complex-mediated actin nucleation (GO:0034314)2.89877139
113negative regulation of leukocyte mediated immunity (GO:0002704)2.88899730
114regulation of T cell mediated cytotoxicity (GO:0001914)2.88766046
115positive regulation of B cell activation (GO:0050871)2.88193529
116positive regulation of granulocyte differentiation (GO:0030854)2.88191930
117negative regulation of bone resorption (GO:0045779)2.87403051
118protein K11-linked deubiquitination (GO:0035871)2.86850465
119cellular response to interferon-beta (GO:0035458)2.86723747
120B cell homeostasis (GO:0001782)2.83329170
121positive regulation of protein homooligomerization (GO:0032464)2.83229354
122hepatocyte apoptotic process (GO:0097284)2.81471653
123cytidine deamination (GO:0009972)2.81174615
124cytidine metabolic process (GO:0046087)2.81174615
125cytidine catabolic process (GO:0006216)2.81174615
126pyrimidine ribonucleoside catabolic process (GO:0046133)2.80491525
127positive regulation of T cell differentiation in thymus (GO:0033089)2.79216583
128T cell activation (GO:0042110)2.78724082
129T-helper cell differentiation (GO:0042093)2.75029312
130CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.75029312
131regulation of T cell mediated immunity (GO:0002709)2.74987399
132CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.70913173
133positive regulation of alpha-beta T cell activation (GO:0046635)2.70657002
134neural tube formation (GO:0001841)2.67726444
135negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.65636544
136negative regulation of T-helper cell differentiation (GO:0045623)2.65389293

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.03262227
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.27108400
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.66210627
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.33841837
5E2F7_22180533_ChIP-Seq_HELA_Human3.91509755
6MYC_22102868_ChIP-Seq_BL_Human3.74367933
7SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.42528582
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.22581924
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.01332892
10RUNX_20019798_ChIP-Seq_JUKART_Human3.00985753
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.99287096
12FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.89799647
13MYB_26560356_Chip-Seq_TH2_Human2.85974174
14STAT4_19710469_ChIP-ChIP_TH1__Mouse2.85943249
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.83763143
16MAF_26560356_Chip-Seq_TH1_Human2.65649658
17* MYB_26560356_Chip-Seq_TH1_Human2.59621895
18SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.58110506
19BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.56191253
20RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.51261376
21* VDR_21846776_ChIP-Seq_THP-1_Human2.50262363
22UTX_26944678_Chip-Seq_JUKART_Human2.39074957
23SCL_19346495_ChIP-Seq_HPC-7_Human2.35662279
24E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.30514204
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.28940223
26FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.21182489
27FLI1_27457419_Chip-Seq_LIVER_Mouse2.19074834
28SPI1_23547873_ChIP-Seq_NB4_Human2.17840894
29* NOTCH1_21737748_ChIP-Seq_TLL_Human2.11416589
30ZNF274_21170338_ChIP-Seq_K562_Hela2.11255457
31IRF8_27001747_Chip-Seq_BMDM_Mouse2.07200735
32SMAD_19615063_ChIP-ChIP_OVARY_Human2.06358142
33EGR1_19374776_ChIP-ChIP_THP-1_Human2.03517068
34RUNX1_22412390_ChIP-Seq_EML_Mouse1.94094873
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.93676632
36VDR_22108803_ChIP-Seq_LS180_Human1.91085239
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.90276242
38CIITA_25753668_ChIP-Seq_RAJI_Human1.89337036
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.87997218
40NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.85646777
41MAF_26560356_Chip-Seq_TH2_Human1.83464095
42SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.81195450
43VDR_24763502_ChIP-Seq_THP-1_Human1.80661584
44MYB_21317192_ChIP-Seq_ERMYB_Mouse1.78039007
45TCF7_22412390_ChIP-Seq_EML_Mouse1.76914288
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.75833725
47* GATA3_27048872_Chip-Seq_THYMUS_Human1.72252197
48MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.67713193
49KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.66783651
50SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.65357951
51SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.62421782
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.61132026
53BRD4_27068464_Chip-Seq_AML-cells_Mouse1.52569971
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.48426066
55* VDR_23849224_ChIP-Seq_CD4+_Human1.46642693
56NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.45530415
57* FOXP3_21729870_ChIP-Seq_TREG_Human1.44631983
58* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.41954952
59NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.41306043
60GATA1_22025678_ChIP-Seq_K562_Human1.40979877
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39837682
62PCGF2_27294783_Chip-Seq_NPCs_Mouse1.38115550
63ER_23166858_ChIP-Seq_MCF-7_Human1.37716162
64LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.36481519
65HOXB4_20404135_ChIP-ChIP_EML_Mouse1.35116589
66SPI1_23127762_ChIP-Seq_K562_Human1.33893006
67KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.32238942
68VDR_24787735_ChIP-Seq_THP-1_Human1.31309658
69SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29603346
70* NFE2_27457419_Chip-Seq_LIVER_Mouse1.28782607
71POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27154053
72LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.27034119
73PU.1_20513432_ChIP-Seq_Bcells_Mouse1.26988112
74KDM2B_26808549_Chip-Seq_DND41_Human1.25601369
75E2F4_17652178_ChIP-ChIP_JURKAT_Human1.24864782
76SMRT_27268052_Chip-Seq_Bcells_Human1.24842584
77NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.24633371
78* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.20781176
79IRF1_19129219_ChIP-ChIP_H3396_Human1.17842369
80* EZH2_27294783_Chip-Seq_NPCs_Mouse1.15467471
81GATA3_26560356_Chip-Seq_TH1_Human1.14516842
82* GATA3_26560356_Chip-Seq_TH2_Human1.14291523
83PRDM14_20953172_ChIP-Seq_ESCs_Human1.13646953
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13521111
85IGF1R_20145208_ChIP-Seq_DFB_Human1.11299977
86KDM2B_26808549_Chip-Seq_SUP-B15_Human1.11218639
87VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10577971
88RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.10346328
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10264734
90RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.09811779
91PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09774169
92BP1_19119308_ChIP-ChIP_Hs578T_Human1.09196185
93PU_27001747_Chip-Seq_BMDM_Mouse1.09151671
94* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08684196
95TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.08257471
96GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06182719
97FOXM1_23109430_ChIP-Seq_U2OS_Human1.05808594
98MYC_18555785_ChIP-Seq_MESCs_Mouse1.04961175
99ELK3_25401928_ChIP-Seq_HUVEC_Human1.04257393
100EST1_17652178_ChIP-ChIP_JURKAT_Human1.02563710
101CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02498025
102TP53_22573176_ChIP-Seq_HFKS_Human1.01337140
103TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00491280
104FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.97631740
105* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.97421150
106BCAT_22108803_ChIP-Seq_LS180_Human0.97029318
107GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96796201
108* GABP_17652178_ChIP-ChIP_JURKAT_Human0.96101677
109CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95584557
110* OCT4_21477851_ChIP-Seq_ESCs_Mouse0.95371282
111GBX2_23144817_ChIP-Seq_PC3_Human0.94810542
112* CRX_20693478_ChIP-Seq_RETINA_Mouse0.94509892
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93275228
114AR_21572438_ChIP-Seq_LNCaP_Human0.92635394
115EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.91443652
116* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.91376763
117XRN2_22483619_ChIP-Seq_HELA_Human0.91354225
118CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.90930140
119CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.90568493
120EWS_26573619_Chip-Seq_HEK293_Human0.89485590
121FOXA1_27270436_Chip-Seq_PROSTATE_Human0.89214772
122FOXA1_25329375_ChIP-Seq_VCAP_Human0.89214772
123* RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88248723
124* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.88180652
125MYC_19079543_ChIP-ChIP_MESCs_Mouse0.87978741
126FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.87880944
127SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87746935
128VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.87618915
129EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.87520212
130ELK1_19687146_ChIP-ChIP_HELA_Human0.87194514
131* GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.86504592
132TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.85757661
133NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.85108700
134GATA1_19941827_ChIP-Seq_MEL_Mouse0.84869596
135GATA3_21878914_ChIP-Seq_MCF-7_Human0.84779020
136RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84070349
137KDM5A_27292631_Chip-Seq_BREAST_Human0.83182961
138EGR1_23403033_ChIP-Seq_LIVER_Mouse0.82921728
139CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82450734
140HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.82271854
141FOXA1_21572438_ChIP-Seq_LNCaP_Human0.81507978
142CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80615766
143TAF15_26573619_Chip-Seq_HEK293_Human0.80089012
144GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.79741533
145* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78823034
146BCL6_27268052_Chip-Seq_Bcells_Human0.78249297
147MYC_18358816_ChIP-ChIP_MESCs_Mouse0.78244961
148ETS1_20019798_ChIP-Seq_JURKAT_Human0.78032568
149SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.77872752
150CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.77853496
151PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.77298681
152JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.76336945

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.89873591
2MP0005671_abnormal_response_to4.54875386
3MP0003763_abnormal_thymus_physiology4.37410493
4* MP0001800_abnormal_humoral_immune4.03113497
5MP0000685_abnormal_immune_system3.85084745
6MP0005387_immune_system_phenotype3.72207564
7MP0001790_abnormal_immune_system3.72207564
8* MP0002452_abnormal_antigen_presenting3.17766298
9MP0005000_abnormal_immune_tolerance3.16710275
10* MP0002420_abnormal_adaptive_immunity3.13680189
11* MP0002723_abnormal_immune_serum3.08850379
12* MP0002398_abnormal_bone_marrow3.06360707
13* MP0001819_abnormal_immune_cell3.05949695
14MP0002396_abnormal_hematopoietic_system3.00521532
15MP0009785_altered_susceptibility_to2.94414474
16* MP0000716_abnormal_immune_system2.70242849
17MP0003787_abnormal_imprinting2.69197476
18MP0005025_abnormal_response_to2.65603617
19MP0002166_altered_tumor_susceptibility2.56550900
20* MP0000689_abnormal_spleen_morphology2.54600173
21MP0008877_abnormal_DNA_methylation2.51469872
22MP0002722_abnormal_immune_system2.43388215
23MP0009333_abnormal_splenocyte_physiolog2.31252120
24MP0001873_stomach_inflammation2.30733991
25* MP0002429_abnormal_blood_cell2.25978110
26MP0002405_respiratory_system_inflammati2.24067140
27MP0000703_abnormal_thymus_morphology2.19722016
28MP0010155_abnormal_intestine_physiology2.08892773
29MP0002148_abnormal_hypersensitivity_rea2.07333704
30MP0003436_decreased_susceptibility_to2.06612113
31MP0002006_tumorigenesis2.02745550
32MP0002419_abnormal_innate_immunity1.97905403
33MP0006082_CNS_inflammation1.93261025
34MP0004947_skin_inflammation1.91440821
35MP0003866_abnormal_defecation1.87370512
36MP0001845_abnormal_inflammatory_respons1.78040460
37MP0002933_joint_inflammation1.77854027
38MP0005464_abnormal_platelet_physiology1.75738975
39MP0004808_abnormal_hematopoietic_stem1.75517690
40MP0000569_abnormal_digit_pigmentation1.74358477
41MP0002138_abnormal_hepatobiliary_system1.71824434
42MP0003303_peritoneal_inflammation1.69968507
43MP0001853_heart_inflammation1.64673776
44MP0003300_gastrointestinal_ulcer1.63294459
45MP0002277_abnormal_respiratory_mucosa1.49134667
46MP0004510_myositis1.39265857
47MP0001986_abnormal_taste_sensitivity1.37691188
48MP0005174_abnormal_tail_pigmentation1.31568728
49MP0002019_abnormal_tumor_incidence1.30920308
50MP0005310_abnormal_salivary_gland1.28756969
51MP0000490_abnormal_crypts_of1.24918633
52MP0000465_gastrointestinal_hemorrhage1.24649723
53MP0001501_abnormal_sleep_pattern1.24413486
54MP0005075_abnormal_melanosome_morpholog1.21371166
55MP0008469_abnormal_protein_level1.20584220
56MP0000858_altered_metastatic_potential1.17485310
57MP0008057_abnormal_DNA_replication1.14459694
58MP0003724_increased_susceptibility_to1.14204033
59MP0005397_hematopoietic_system_phenotyp1.08529124
60MP0001545_abnormal_hematopoietic_system1.08529124
61MP0002163_abnormal_gland_morphology1.07065876
62MP0001919_abnormal_reproductive_system1.05474073
63MP0005645_abnormal_hypothalamus_physiol1.03882692
64MP0003077_abnormal_cell_cycle1.00540510
65MP0010094_abnormal_chromosome_stability0.99455433
66MP0002095_abnormal_skin_pigmentation0.94783616
67MP0008007_abnormal_cellular_replicative0.90761210
68MP0008872_abnormal_physiological_respon0.89307526
69MP0000015_abnormal_ear_pigmentation0.87894063
70MP0003448_altered_tumor_morphology0.86850213
71MP0003693_abnormal_embryo_hatching0.86404536
72MP0002638_abnormal_pupillary_reflex0.85267681
73MP0002653_abnormal_ependyma_morphology0.84546717
74MP0008995_early_reproductive_senescence0.83101255
75MP0002132_abnormal_respiratory_system0.79712011
76MP0004957_abnormal_blastocyst_morpholog0.77802659
77MP0000427_abnormal_hair_cycle0.75491880
78MP0004142_abnormal_muscle_tone0.74520230
79MP0005551_abnormal_eye_electrophysiolog0.74068146
80MP0001533_abnormal_skeleton_physiology0.73435997
81MP0006054_spinal_hemorrhage0.72456862
82MP0002876_abnormal_thyroid_physiology0.72229942
83MP0000372_irregular_coat_pigmentation0.71361498
84MP0010352_gastrointestinal_tract_polyps0.70502419
85MP0002136_abnormal_kidney_physiology0.70315070
86MP0008058_abnormal_DNA_repair0.69993867
87MP0009278_abnormal_bone_marrow0.69297619
88MP0003183_abnormal_peptide_metabolism0.69091335
89MP0001764_abnormal_homeostasis0.67599117
90MP0003045_fibrosis0.67373679
91MP0004742_abnormal_vestibular_system0.67196279
92MP0004043_abnormal_pH_regulation0.66401281
93MP0009765_abnormal_xenobiotic_induced0.65558371
94MP0000477_abnormal_intestine_morphology0.65138045
95MP0009763_increased_sensitivity_to0.64939101
96MP0005379_endocrine/exocrine_gland_phen0.63812704
97MP0002254_reproductive_system_inflammat0.62919573
98MP0002102_abnormal_ear_morphology0.61705314
99MP0010234_abnormal_vibrissa_follicle0.60951875
100MP0000313_abnormal_cell_death0.60855654
101MP0004883_abnormal_blood_vessel0.59745807
102MP0009764_decreased_sensitivity_to0.59250751
103MP0005023_abnormal_wound_healing0.58876773
104MP0004381_abnormal_hair_follicle0.58750135
105MP0003646_muscle_fatigue0.58688305
106MP0001191_abnormal_skin_condition0.57702253
107MP0003252_abnormal_bile_duct0.57436601
108MP0001663_abnormal_digestive_system0.56108781
109MP0005266_abnormal_metabolism0.55249573
110MP0003943_abnormal_hepatobiliary_system0.55187699
111MP0005389_reproductive_system_phenotype0.55131692
112MP0001851_eye_inflammation0.53939957
113MP0005253_abnormal_eye_physiology0.51679343
114MP0003111_abnormal_nucleus_morphology0.51448060
115MP0002693_abnormal_pancreas_physiology0.51094065
116MP0002009_preneoplasia0.50629235
117MP0002998_abnormal_bone_remodeling0.46986047
118MP0001765_abnormal_ion_homeostasis0.46250266
119MP0003195_calcinosis0.46028366
120MP0000609_abnormal_liver_physiology0.45395975
121MP0005167_abnormal_blood-brain_barrier0.45278539
122MP0005376_homeostasis/metabolism_phenot0.45004568
123MP0002083_premature_death0.44869851
124MP0000350_abnormal_cell_proliferation0.44440794
125MP0008961_abnormal_basal_metabolism0.44434770
126MP0001879_abnormal_lymphatic_vessel0.42551753
127MP0003172_abnormal_lysosome_physiology0.41592408
128MP0008873_increased_physiological_sensi0.41538320
129MP0000249_abnormal_blood_vessel0.40397978
130MP0000371_diluted_coat_color0.40149374
131MP0000598_abnormal_liver_morphology0.39450227
132MP0002928_abnormal_bile_duct0.38925128
133MP0005058_abnormal_lysosome_morphology0.37346591
134MP0003795_abnormal_bone_structure0.36098815
135MP0005166_decreased_susceptibility_to0.35971604

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)6.70833350
2Recurrent bronchitis (HP:0002837)6.67435785
3IgM deficiency (HP:0002850)5.86861800
4Gastrointestinal stroma tumor (HP:0100723)5.30408192
5Chronic otitis media (HP:0000389)5.21545415
6Recurrent sinusitis (HP:0011108)5.15414051
7Abnormality of B cell number (HP:0010975)4.99351312
8B lymphocytopenia (HP:0010976)4.99351312
9Recurrent viral infections (HP:0004429)4.83949616
10T lymphocytopenia (HP:0005403)4.81710512
11Panhypogammaglobulinemia (HP:0003139)4.69247656
12Abnormality of T cell number (HP:0011839)4.65120564
13Lymphopenia (HP:0001888)4.44271381
14Colitis (HP:0002583)4.44165457
15Abnormality of T cells (HP:0002843)4.42978225
16Elevated erythrocyte sedimentation rate (HP:0003565)4.37601545
17IgG deficiency (HP:0004315)4.29581552
18Inflammation of the large intestine (HP:0002037)4.27885281
19Meningitis (HP:0001287)4.24722426
20Abnormality of cells of the lymphoid lineage (HP:0012140)4.23270957
21Abnormal delayed hypersensitivity skin test (HP:0002963)4.19611572
22Cellulitis (HP:0100658)4.16527010
23Gastrointestinal inflammation (HP:0004386)4.13845784
24Nasal polyposis (HP:0100582)3.95616507
25Chronic sinusitis (HP:0011109)3.91733985
26Recurrent fungal infections (HP:0002841)3.91121853
27Abnormality of T cell physiology (HP:0011840)3.89355256
28Verrucae (HP:0200043)3.86048126
29Papilloma (HP:0012740)3.86048126
30IgA deficiency (HP:0002720)3.85907110
31Bronchitis (HP:0012387)3.83841718
32Recurrent cutaneous fungal infections (HP:0011370)3.76313680
33Chronic mucocutaneous candidiasis (HP:0002728)3.76313680
34Myositis (HP:0100614)3.73730914
35Gastrointestinal infarctions (HP:0005244)3.66181306
36Vasculitis (HP:0002633)3.64173731
37Stomach cancer (HP:0012126)3.62907982
38Emphysema (HP:0002097)3.53690674
39Thyroiditis (HP:0100646)3.53449741
40Severe combined immunodeficiency (HP:0004430)3.52795853
41Recurrent abscess formation (HP:0002722)3.52226699
42Chronic diarrhea (HP:0002028)3.45012229
43Combined immunodeficiency (HP:0005387)3.41008342
44Abnormality of the nasal mucosa (HP:0000433)3.34105084
45Thrombocytosis (HP:0001894)3.28546743
46Abnormality of the fingertips (HP:0001211)3.25558846
47Eczematoid dermatitis (HP:0000976)3.23087677
48Recurrent otitis media (HP:0000403)3.17078882
49Lymphoma (HP:0002665)3.12742286
50Pustule (HP:0200039)3.11545733
51Prostate neoplasm (HP:0100787)3.03501028
52Recurrent bacterial skin infections (HP:0005406)2.97434540
53Recurrent pneumonia (HP:0006532)2.94370896
54Recurrent skin infections (HP:0001581)2.91344020
55Encephalitis (HP:0002383)2.89100965
56Mediastinal lymphadenopathy (HP:0100721)2.84522770
57Recurrent lower respiratory tract infections (HP:0002783)2.79281161
58Restrictive lung disease (HP:0002091)2.74852703
59Basal cell carcinoma (HP:0002671)2.68016506
60Stomatitis (HP:0010280)2.67098399
61Autoimmune hemolytic anemia (HP:0001890)2.66849907
62Keratoconjunctivitis (HP:0001096)2.65659393
63Congenital stationary night blindness (HP:0007642)2.62153488
64Osteomyelitis (HP:0002754)2.60284863
65Abnormality of eosinophils (HP:0001879)2.60271392
66Autoimmune thrombocytopenia (HP:0001973)2.52187828
67Skin rash (HP:0000988)2.47961962
68Interstitial pulmonary disease (HP:0006530)2.46291512
69Obstructive lung disease (HP:0006536)2.46015969
70Chronic obstructive pulmonary disease (HP:0006510)2.46015969
71Increased IgE level (HP:0003212)2.38635096
72Pulmonary infiltrates (HP:0002113)2.37983551
73Pancreatic cysts (HP:0001737)2.36789835
74Sepsis (HP:0100806)2.34908523
75Eosinophilia (HP:0001880)2.31296200
76Hypergammaglobulinemia (HP:0010702)2.26646516
77Hypoplasia of the thymus (HP:0000778)2.25996513
78Abnormality of male internal genitalia (HP:0000022)2.25727469
79Leukocytosis (HP:0001974)2.23557213
80Abnormality of the renal cortex (HP:0011035)2.22783114
81Optic neuritis (HP:0100653)2.21876238
82Retrobulbar optic neuritis (HP:0100654)2.21876238
83Granulocytopenia (HP:0001913)2.21642630
84Leukopenia (HP:0001882)2.21259058
85Spontaneous hematomas (HP:0007420)2.18491823
86Skin ulcer (HP:0200042)2.18361555
87Prolonged bleeding time (HP:0003010)2.17318407
88Increased IgM level (HP:0003496)2.17254469
89Joint swelling (HP:0001386)2.16163300
90Bronchiectasis (HP:0002110)2.11144311
91Abnormality of the pleura (HP:0002103)2.08379984
92Gangrene (HP:0100758)2.08141953
93Pulmonary embolism (HP:0002204)2.07217777
94Hypochromic anemia (HP:0001931)2.06960065
95Viral hepatitis (HP:0006562)2.06345370
96Hemoptysis (HP:0002105)2.04912499
97Poikiloderma (HP:0001029)2.04422699
98Neutropenia (HP:0001875)2.04238873
99Chronic hepatic failure (HP:0100626)2.03670716
100Epistaxis (HP:0000421)2.02750472
101Decreased circulating renin level (HP:0003351)2.00303191
102Orchitis (HP:0100796)1.98653782
103Anorexia (HP:0002039)1.95559083
104Papilledema (HP:0001085)1.94916695
105Arthralgia (HP:0002829)1.94374341
106Alveolar cell carcinoma (HP:0006519)1.94041562
107Arterial thrombosis (HP:0004420)1.93784370
108Abnormality of macrophages (HP:0004311)1.93096486
109Entropion (HP:0000621)1.92428545
110Attenuation of retinal blood vessels (HP:0007843)1.92312695
111Chest pain (HP:0100749)1.89480927
112Neoplasm of the tracheobronchial system (HP:0100552)1.89245071
113Hypoproteinemia (HP:0003075)1.86859609
114Hypochromic microcytic anemia (HP:0004840)1.84462509
115Keratoconjunctivitis sicca (HP:0001097)1.83463512
116Pancreatic fibrosis (HP:0100732)1.82530812
117Hepatitis (HP:0012115)1.81522705
118Keratitis (HP:0000491)1.80992511
119Urticaria (HP:0001025)1.80251903
120Petechiae (HP:0000967)1.80058566
121Microcytic anemia (HP:0001935)1.78553979
122Absent rod-and cone-mediated responses on ERG (HP:0007688)1.78447904
123Abnormality of the prostate (HP:0008775)1.77219163
124Hyperventilation (HP:0002883)1.77035249
125Abnormality of midbrain morphology (HP:0002418)1.74949466
126Molar tooth sign on MRI (HP:0002419)1.74949466
127Amaurosis fugax (HP:0100576)1.74944637
128Acute hepatic failure (HP:0006554)1.74507329

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K16.68732774
2TXK3.59081355
3FRK3.29645521
4KIT2.84999706
5JAK32.81823459
6GRK62.54264288
7TYK22.46017214
8ITK2.43118548
9ZAP702.40619304
10BTK2.38901905
11IKBKE2.36288506
12SYK2.30150957
13CSF1R2.29064760
14STK102.19569332
15FGFR42.15737200
16BLK2.14243770
17MAP3K132.12098333
18TBK12.08562956
19TEC2.03697647
20JAK11.95072306
21ERN11.93973785
22MAP3K141.85119046
23LCK1.78995346
24IRAK41.72774787
25FLT31.71251406
26LRRK21.69234056
27MAP3K101.63386132
28EEF2K1.54442007
29NME21.47520674
30LYN1.40326610
31CSK1.39261163
32HCK1.36200862
33FGFR31.35345811
34ZAK1.33045015
35NLK1.32610077
36KDR1.28843080
37IRAK11.27785318
38SIK21.27402317
39CAMKK21.26999599
40CLK11.25212135
41BMPR1B1.22366632
42GRK11.16349870
43IKBKB1.14746744
44NUAK11.14218067
45FES1.08823768
46SIK31.05942970
47PRKCQ1.03345187
48PRKCH1.01292220
49WNK31.01110673
50MAPK131.00090158
51TESK20.99934696
52PINK10.98438919
53MST40.96434275
54RPS6KA40.93782819
55MAP4K20.91857981
56PIM10.90311471
57TGFBR20.86720872
58MARK30.86023784
59BMPR20.83165426
60RIPK40.82985928
61PKN20.77610555
62INSRR0.76539911
63PAK30.76537958
64TAOK30.75008334
65IRAK30.74796651
66ADRBK20.73838217
67PTK2B0.73366145
68PIK3CG0.72542348
69HIPK20.68673111
70TNK20.68606540
71MAP2K20.66717616
72CAMKK10.66459725
73CDK40.64066171
74CHUK0.62799719
75MAP3K70.62251161
76MAP2K30.61507891
77NEK20.56917256
78TRIM280.56130224
79TRPM70.56085562
80MAP3K120.53963434
81TGFBR10.53518794
82CDC70.53370469
83EIF2AK30.52606182
84CDK120.51887209
85YES10.51333253
86BRD40.50314889
87PRPF4B0.49723961
88PASK0.49023875
89MAP2K60.47840606
90JAK20.45468805
91PDK10.44798896
92ADRBK10.44752461
93RPS6KB20.42483147
94SGK20.42145164
95MAPK110.41993085
96RAF10.41845174
97OXSR10.39774323
98FGR0.39456864
99STK110.39450701
100MAPKAPK30.39157773
101ACVR1B0.38939753
102TLK10.38584842
103RPS6KA50.37794561
104STK40.36424951
105STK240.36036949
106FYN0.35621226
107MATK0.35385342
108EPHB10.34790604
109IRAK20.34129031
110GRK70.33392740
111MAPK150.33086304
112PRKD20.32827372
113ABL10.32089671
114ALK0.30302502
115CAMK40.30061714
116MELK0.29921232
117MARK20.29541791
118MAP3K80.29378974
119SIK10.28655989
120EIF2AK10.28341908
121ATR0.27774771
122INSR0.27586376
123MAPK70.27363698
124PIK3CA0.26690284
125MAPK120.26217616
126CDK60.25860402
127CDK90.25108927
128EGFR0.24887896
129MAPK30.24843824
130PRKCD0.24336696
131GRK50.23674838
132EPHA30.23081925
133MAPK40.22834170
134TRIB30.22526190
135NTRK20.22078001
136IGF1R0.22009173
137MAP3K40.21252333
138RPS6KA60.20374208

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.33076077
2B cell receptor signaling pathway_Homo sapiens_hsa046623.42888233
3Intestinal immune network for IgA production_Homo sapiens_hsa046723.29982289
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.92371119
5Antigen processing and presentation_Homo sapiens_hsa046122.91979371
6T cell receptor signaling pathway_Homo sapiens_hsa046602.80182699
7Hematopoietic cell lineage_Homo sapiens_hsa046402.68214527
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.51468499
9Measles_Homo sapiens_hsa051622.41139430
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.37428010
11Graft-versus-host disease_Homo sapiens_hsa053322.32020674
12Allograft rejection_Homo sapiens_hsa053302.12807747
13Ribosome_Homo sapiens_hsa030102.04310550
14Leishmaniasis_Homo sapiens_hsa051402.02840720
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.81091145
16Osteoclast differentiation_Homo sapiens_hsa043801.79397345
17DNA replication_Homo sapiens_hsa030301.76979450
18Herpes simplex infection_Homo sapiens_hsa051681.76504721
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.75989795
20Base excision repair_Homo sapiens_hsa034101.62455176
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.54423645
22Viral myocarditis_Homo sapiens_hsa054161.52719902
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.50106031
24Non-homologous end-joining_Homo sapiens_hsa034501.46033030
25Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.44189473
26Linoleic acid metabolism_Homo sapiens_hsa005911.41806134
27Mismatch repair_Homo sapiens_hsa034301.39132836
28Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.29616490
29Toll-like receptor signaling pathway_Homo sapiens_hsa046201.21293015
30Leukocyte transendothelial migration_Homo sapiens_hsa046701.20215772
31Chemokine signaling pathway_Homo sapiens_hsa040621.17711353
32Hepatitis B_Homo sapiens_hsa051611.17511313
33Acute myeloid leukemia_Homo sapiens_hsa052211.16229950
34Autoimmune thyroid disease_Homo sapiens_hsa053201.14328870
35Toxoplasmosis_Homo sapiens_hsa051451.13791219
36Shigellosis_Homo sapiens_hsa051311.12362558
37Influenza A_Homo sapiens_hsa051641.11233358
38NOD-like receptor signaling pathway_Homo sapiens_hsa046211.09272728
39Phototransduction_Homo sapiens_hsa047441.08593891
40Epstein-Barr virus infection_Homo sapiens_hsa051691.07795136
41Rheumatoid arthritis_Homo sapiens_hsa053231.07056886
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.04188599
43Spliceosome_Homo sapiens_hsa030401.04051739
44Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.97577586
45HTLV-I infection_Homo sapiens_hsa051660.97456852
46Malaria_Homo sapiens_hsa051440.97000322
47Apoptosis_Homo sapiens_hsa042100.96029631
48Platelet activation_Homo sapiens_hsa046110.90989816
49Tuberculosis_Homo sapiens_hsa051520.89355415
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88947087
51Ether lipid metabolism_Homo sapiens_hsa005650.88481607
52Protein export_Homo sapiens_hsa030600.88404259
53Dorso-ventral axis formation_Homo sapiens_hsa043200.86665367
54Pancreatic cancer_Homo sapiens_hsa052120.86591301
55Legionellosis_Homo sapiens_hsa051340.85763658
56Nucleotide excision repair_Homo sapiens_hsa034200.83599592
57Homologous recombination_Homo sapiens_hsa034400.82913261
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81919363
59Nitrogen metabolism_Homo sapiens_hsa009100.81694727
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80435127
61Type I diabetes mellitus_Homo sapiens_hsa049400.77511576
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75611064
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74978426
64Viral carcinogenesis_Homo sapiens_hsa052030.74565271
65TNF signaling pathway_Homo sapiens_hsa046680.72533568
66p53 signaling pathway_Homo sapiens_hsa041150.71662348
67Regulation of autophagy_Homo sapiens_hsa041400.70309148
68Hepatitis C_Homo sapiens_hsa051600.69405579
69Chronic myeloid leukemia_Homo sapiens_hsa052200.67278336
70RNA degradation_Homo sapiens_hsa030180.66980618
71ABC transporters_Homo sapiens_hsa020100.65009955
72VEGF signaling pathway_Homo sapiens_hsa043700.63372403
73Pertussis_Homo sapiens_hsa051330.62568936
74Non-small cell lung cancer_Homo sapiens_hsa052230.61394985
75Basal transcription factors_Homo sapiens_hsa030220.60102323
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60045333
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.58280419
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57658571
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.57099447
80Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56692706
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55843525
82Colorectal cancer_Homo sapiens_hsa052100.55838789
83AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54757121
84Pyrimidine metabolism_Homo sapiens_hsa002400.54515530
85Asthma_Homo sapiens_hsa053100.53706419
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52650866
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50988631
88Glycerolipid metabolism_Homo sapiens_hsa005610.50706693
89Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.50499732
90N-Glycan biosynthesis_Homo sapiens_hsa005100.47974175
91African trypanosomiasis_Homo sapiens_hsa051430.46908240
92Prolactin signaling pathway_Homo sapiens_hsa049170.46330326
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.45820467
94Other glycan degradation_Homo sapiens_hsa005110.44736945
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44163265
96Caffeine metabolism_Homo sapiens_hsa002320.43243725
97Arachidonic acid metabolism_Homo sapiens_hsa005900.42864511
98Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42151501
99Butanoate metabolism_Homo sapiens_hsa006500.41561748
100Salmonella infection_Homo sapiens_hsa051320.41363302
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.41280727
102Fanconi anemia pathway_Homo sapiens_hsa034600.40304605
103Proteasome_Homo sapiens_hsa030500.40287781
104Morphine addiction_Homo sapiens_hsa050320.39390268
105RNA polymerase_Homo sapiens_hsa030200.38871738
106Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36833710
107Olfactory transduction_Homo sapiens_hsa047400.35578948
108Notch signaling pathway_Homo sapiens_hsa043300.34561648
109Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.33891875
110Small cell lung cancer_Homo sapiens_hsa052220.33752041
111Phagosome_Homo sapiens_hsa041450.33616082
112Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33299959
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32725514
114Cell cycle_Homo sapiens_hsa041100.32392421
115Serotonergic synapse_Homo sapiens_hsa047260.32360408
116Systemic lupus erythematosus_Homo sapiens_hsa053220.32086519
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.30823438
118RNA transport_Homo sapiens_hsa030130.30171937
119Selenocompound metabolism_Homo sapiens_hsa004500.29762877
120Circadian rhythm_Homo sapiens_hsa047100.29521523
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.29411478
122Staphylococcus aureus infection_Homo sapiens_hsa051500.29189042
123Cholinergic synapse_Homo sapiens_hsa047250.22467581
124mRNA surveillance pathway_Homo sapiens_hsa030150.22369640
125Endocytosis_Homo sapiens_hsa041440.22062096
126Sphingolipid signaling pathway_Homo sapiens_hsa040710.21418870
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.20967758
128Taste transduction_Homo sapiens_hsa047420.20751680
129Inositol phosphate metabolism_Homo sapiens_hsa005620.20306161
130MAPK signaling pathway_Homo sapiens_hsa040100.19534192
131Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.19450520
132FoxO signaling pathway_Homo sapiens_hsa040680.18493185
133Regulation of actin cytoskeleton_Homo sapiens_hsa048100.16594195
134Pentose phosphate pathway_Homo sapiens_hsa000300.16042585

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