LCE1C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)9.05752236
2hair cycle (GO:0042633)8.90084172
3molting cycle (GO:0042303)8.90084172
4multicellular organismal water homeostasis (GO:0050891)8.79230669
5keratinocyte differentiation (GO:0030216)8.76052026
6peptide cross-linking (GO:0018149)8.42239469
7water homeostasis (GO:0030104)7.33172190
8glucosamine-containing compound catabolic process (GO:1901072)6.79628005
9epidermal cell differentiation (GO:0009913)6.75232676
10long-chain fatty acid biosynthetic process (GO:0042759)6.36369995
11intermediate filament organization (GO:0045109)5.74850955
12bundle of His cell to Purkinje myocyte communication (GO:0086069)5.70391197
13keratinocyte proliferation (GO:0043616)5.69162627
14epidermis development (GO:0008544)5.55025833
15fatty acid elongation (GO:0030497)5.44677570
16skin morphogenesis (GO:0043589)5.41422944
17regulation of type B pancreatic cell apoptotic process (GO:2000674)5.34771435
18G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)5.13158166
19regulation of hypersensitivity (GO:0002883)4.60175674
20linoleic acid metabolic process (GO:0043651)4.58458404
21regulation of ruffle assembly (GO:1900027)4.53347490
22surfactant homeostasis (GO:0043129)4.36010190
23regulation of natural killer cell differentiation (GO:0032823)4.33850544
24keratinocyte development (GO:0003334)4.26462638
25positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.22935975
26establishment of planar polarity (GO:0001736)4.05025896
27establishment of tissue polarity (GO:0007164)4.05025896
28ectoderm development (GO:0007398)4.03914383
29negative regulation of interferon-gamma production (GO:0032689)4.03856026
30lateral sprouting from an epithelium (GO:0060601)3.94603273
31negative regulation of catenin import into nucleus (GO:0035414)3.89596807
32epithelial cell differentiation involved in prostate gland development (GO:0060742)3.80773293
33chemical homeostasis within a tissue (GO:0048875)3.80472038
34ceramide biosynthetic process (GO:0046513)3.76267605
35polarized epithelial cell differentiation (GO:0030859)3.74343398
36intermediate filament cytoskeleton organization (GO:0045104)3.67507848
37positive regulation of interleukin-8 secretion (GO:2000484)3.64519084
38lipoxygenase pathway (GO:0019372)3.61489559
39phosphatidylserine metabolic process (GO:0006658)3.58962958
40cellular response to calcium ion (GO:0071277)3.57365744
41intermediate filament-based process (GO:0045103)3.53543184
42negative regulation of muscle hypertrophy (GO:0014741)3.49247657
43phosphatidylinositol acyl-chain remodeling (GO:0036149)3.47954482
44skin development (GO:0043588)3.47719193
45positive regulation of cholesterol efflux (GO:0010875)3.46643899
46sphingosine metabolic process (GO:0006670)3.39652441
47positive regulation of cellular amide metabolic process (GO:0034250)3.38106315
48long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.36811174
49primary alcohol catabolic process (GO:0034310)3.36304060
50fibrinolysis (GO:0042730)3.32540306
51positive regulation of epidermal cell differentiation (GO:0045606)3.29780316
52sphingoid metabolic process (GO:0046519)3.27980752
53phosphatidylserine acyl-chain remodeling (GO:0036150)3.19487494
54regulation of transforming growth factor beta1 production (GO:0032908)3.17825611
55hair follicle morphogenesis (GO:0031069)3.17431142
56gap junction assembly (GO:0016264)3.15079153
57thymic T cell selection (GO:0045061)3.11222599
58negative regulation of cell fate specification (GO:0009996)3.10129355
59defense response to fungus (GO:0050832)3.08333798
60phospholipid catabolic process (GO:0009395)3.01440746
61cell-substrate junction assembly (GO:0007044)3.01406192
62positive regulation of cholesterol transport (GO:0032376)3.00153685
63positive regulation of sterol transport (GO:0032373)3.00153685
64* keratinization (GO:0031424)20.3504305
65negative regulation of stress fiber assembly (GO:0051497)2.99321715
66diol metabolic process (GO:0034311)2.97316210
67negative regulation of keratinocyte proliferation (GO:0010839)2.96940556
68long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.96920215
69G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.95489768
70positive thymic T cell selection (GO:0045059)2.93163281
71detection of bacterium (GO:0016045)2.92952646
72phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.91307165
73phospholipid scrambling (GO:0017121)2.90130778
74regulation of receptor recycling (GO:0001919)2.89767101
75regulation of acute inflammatory response to antigenic stimulus (GO:0002864)2.88728018
76alditol phosphate metabolic process (GO:0052646)2.86562660
77negative regulation of cardiac muscle hypertrophy (GO:0010614)2.85241160
78fatty-acyl-CoA metabolic process (GO:0035337)2.84488081
79detection of external biotic stimulus (GO:0098581)2.84337034
80regulation of keratinocyte proliferation (GO:0010837)2.82814684
81cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.82326716
82fatty-acyl-CoA biosynthetic process (GO:0046949)2.81702346
83regulation of epidermal cell differentiation (GO:0045604)2.80399478
84atrioventricular valve morphogenesis (GO:0003181)2.80284952
85regulation of epidermis development (GO:0045682)2.80262275
86positive regulation of keratinocyte differentiation (GO:0045618)2.79425855
87one-carbon compound transport (GO:0019755)2.75969592
88amino sugar catabolic process (GO:0046348)2.75022571
89negative regulation of interleukin-17 production (GO:0032700)2.73811403
90negative regulation of axon extension involved in axon guidance (GO:0048843)2.73514333
91negative regulation of T cell mediated immunity (GO:0002710)2.71964614
92phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.68875877
93purinergic nucleotide receptor signaling pathway (GO:0035590)2.68741310
94tooth mineralization (GO:0034505)2.67813506
95nuclear envelope reassembly (GO:0031468)2.67376686
96mitotic nuclear envelope reassembly (GO:0007084)2.67376686
97muscle filament sliding (GO:0030049)2.67203332
98actin-myosin filament sliding (GO:0033275)2.67203332
99eyelid development in camera-type eye (GO:0061029)2.66522564
100defense response to Gram-negative bacterium (GO:0050829)2.63302160
101regulation of cholesterol homeostasis (GO:2000188)2.61751862
102virion attachment to host cell (GO:0019062)2.61597231
103adhesion of symbiont to host cell (GO:0044650)2.61597231
104epithelium development (GO:0060429)2.60073901
105positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.59679582
106polyol transport (GO:0015791)2.58904543
107planar cell polarity pathway involved in neural tube closure (GO:0090179)2.57613096
108positive regulation of glomerulus development (GO:0090193)2.57548972
109regulation of keratinocyte differentiation (GO:0045616)2.56481469
110sphingolipid biosynthetic process (GO:0030148)2.56244356
111negative regulation of cell fate commitment (GO:0010454)2.55306379
112negative regulation of cAMP-mediated signaling (GO:0043951)2.54097062
113ethanol metabolic process (GO:0006067)2.52488062
114epithelial cell-cell adhesion (GO:0090136)2.52474004
115regulation of interleukin-8 secretion (GO:2000482)2.51130169
116positive regulation of meiotic cell cycle (GO:0051446)2.50429048
117regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.49004701
118regulation of cell proliferation involved in kidney development (GO:1901722)2.48857984
119phosphatidylglycerol metabolic process (GO:0046471)2.46842655
120ephrin receptor signaling pathway (GO:0048013)2.46685576
121regulation of cardioblast differentiation (GO:0051890)2.46355005
122negative regulation of lipase activity (GO:0060192)2.45993502
123molting cycle process (GO:0022404)2.45938621
124hair cycle process (GO:0022405)2.45938621
125regulation of phospholipase A2 activity (GO:0032429)2.45902182
126dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.45054837
127detection of other organism (GO:0098543)2.41607480
128adhesion of symbiont to host (GO:0044406)2.41271013
129positive T cell selection (GO:0043368)2.40761619
130detection of biotic stimulus (GO:0009595)2.40013692
131T cell selection (GO:0045058)2.39386239
132negative regulation of acute inflammatory response (GO:0002674)2.38595359
133cellular response to antibiotic (GO:0071236)2.37456498
134very long-chain fatty acid metabolic process (GO:0000038)2.36875792
135regulation of axon regeneration (GO:0048679)2.36759697
136regulation of neuron projection regeneration (GO:0070570)2.36759697
137intestinal epithelial cell development (GO:0060576)2.36527103
138regulation of protein localization to cell surface (GO:2000008)2.35733197
139epithelial cell proliferation (GO:0050673)2.35605876
140phosphatidylcholine acyl-chain remodeling (GO:0036151)2.34756001
141ventricular cardiac muscle cell action potential (GO:0086005)2.33920519
142plasma membrane repair (GO:0001778)2.32409860
143phospholipid efflux (GO:0033700)2.31539391
144regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.30849274
145unsaturated fatty acid biosynthetic process (GO:0006636)2.30744706
146positive regulation of epidermis development (GO:0045684)2.30448292
147epithelial cell differentiation (GO:0030855)2.30377530
148retinol metabolic process (GO:0042572)2.29407424
149positive regulation of p38MAPK cascade (GO:1900745)2.28419884
150regulation of cholesterol efflux (GO:0010874)2.18775401
151regulation of heart rate by cardiac conduction (GO:0086091)2.17264677
152positive regulation of monocyte chemotaxis (GO:0090026)2.17246811
153antimicrobial humoral response (GO:0019730)2.15222629
154regulation of natural killer cell activation (GO:0032814)2.14916859
155establishment of skin barrier (GO:0061436)15.3749497
156desmosome organization (GO:0002934)13.4868492
157regulation of water loss via skin (GO:0033561)13.4068944

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.14809845
2P63_26484246_Chip-Seq_KERATINOCYTES_Human3.43178036
3SOX9_24532713_ChIP-Seq_HFSC_Mouse2.22338889
4ESR2_21235772_ChIP-Seq_MCF-7_Human2.21052551
5ZNF263_19887448_ChIP-Seq_K562_Human2.20843961
6SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.19396812
7ESR1_21235772_ChIP-Seq_MCF-7_Human2.13279143
8TP63_17297297_ChIP-ChIP_HaCaT_Human14.0418738
9VDR_22108803_ChIP-Seq_LS180_Human1.84625106
10FOXO3_23340844_ChIP-Seq_DLD1_Human1.82564378
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.81501583
12SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.74206536
13SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.74206536
14TRIM28_21343339_ChIP-Seq_HEK293_Human1.65362481
15GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.61382665
16PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.55717262
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.55295230
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.53747574
19ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.52618287
20RXR_22108803_ChIP-Seq_LS180_Human1.51348728
21TP63_23658742_ChIP-Seq_EP156T_Human1.48555808
22HIF1A_21447827_ChIP-Seq_MCF-7_Human1.45205221
23ZNF217_24962896_ChIP-Seq_MCF-7_Human1.44334997
24GATA6_21074721_ChIP-Seq_CACO-2_Human1.44163933
25TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.43847753
26* CTCF_27219007_Chip-Seq_Bcells_Human1.40959245
27TP63_22573176_ChIP-Seq_HFKS_Human1.40668131
28RARG_19884340_ChIP-ChIP_MEFs_Mouse1.36974756
29CTCF_20526341_ChIP-Seq_ESCs_Human1.36615623
30ERG_20517297_ChIP-Seq_VCAP_Human1.34036711
31RUNX1_27514584_Chip-Seq_MCF-7_Human1.31465918
32SUZ12_27294783_Chip-Seq_ESCs_Mouse1.30028370
33KLF5_25053715_ChIP-Seq_YYC3_Human1.29965124
34RACK7_27058665_Chip-Seq_MCF-7_Human1.27933215
35CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.26418666
36DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24415126
37ATF3_27146783_Chip-Seq_COLON_Human1.23507050
38UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.22255017
39ESR1_20079471_ChIP-ChIP_T-47D_Human1.21192081
40SOX2_20726797_ChIP-Seq_SW620_Human1.20162779
41GATA3_24758297_ChIP-Seq_MCF-7_Human1.19750547
42AR_21572438_ChIP-Seq_LNCaP_Human1.19239719
43BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.18413338
44KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.17420813
45AHR_22903824_ChIP-Seq_MCF-7_Human1.17072332
46CEBPB_22108803_ChIP-Seq_LS180_Human1.15560961
47CJUN_26792858_Chip-Seq_BT549_Human1.14555624
48BCAT_22108803_ChIP-Seq_LS180_Human1.14087981
49ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.14029476
50TP53_20018659_ChIP-ChIP_R1E_Mouse1.13877065
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11130128
52ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.10689193
53FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.07300197
54GATA3_21867929_ChIP-Seq_TH1_Mouse1.06549843
55FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.04677786
56BCOR_27268052_Chip-Seq_Bcells_Human1.03324988
57VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.02063860
58RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00804807
59TP53_18474530_ChIP-ChIP_U2OS_Human1.00590594
60P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.00444635
61EZH2_27294783_Chip-Seq_ESCs_Mouse0.99532480
62LXR_22292898_ChIP-Seq_THP-1_Human0.99464128
63SOX2_27498859_Chip-Seq_STOMACH_Mouse0.98754297
64BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97499400
65SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95376511
66TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94205818
67EZH2_27304074_Chip-Seq_ESCs_Mouse0.93544600
68KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.93020336
69AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.92632330
70JARID2_20075857_ChIP-Seq_MESCs_Mouse0.92207978
71CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.91841769
72EGR1_19032775_ChIP-ChIP_M12_Human0.91189602
73SA1_27219007_Chip-Seq_ERYTHROID_Human0.90992286
74TCF4_18268006_ChIP-ChIP_LS174T_Human0.90977756
75JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89930949
76STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.89622874
77STAT6_21828071_ChIP-Seq_BEAS2B_Human0.89438705
78UBF1/2_26484160_Chip-Seq_HMECs_Human0.89339208
79TCF4_22108803_ChIP-Seq_LS180_Human0.86869692
80CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.85915306
81CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.85690466
82SMC4_20622854_ChIP-Seq_HELA_Human0.85199243
83ERG_21242973_ChIP-ChIP_JURKAT_Human0.84939483
84P53_21459846_ChIP-Seq_SAOS-2_Human0.84499800
85RNF2_27304074_Chip-Seq_ESCs_Mouse0.84409818
86THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83652881
87SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.83070929
88STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.83048957
89GATA4_25053715_ChIP-Seq_YYC3_Human0.83018121
90TAF2_19829295_ChIP-Seq_ESCs_Human0.82872218
91ARNT_22903824_ChIP-Seq_MCF-7_Human0.82234018
92YY1_22570637_ChIP-Seq_MALME-3M_Human0.81944085
93SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.81933838
94P300_27058665_Chip-Seq_ZR-75-30cells_Human0.81623257
95PPAR_26484153_Chip-Seq_NCI-H1993_Human0.81266279
96EZH2_18974828_ChIP-Seq_MESCs_Mouse0.80850904
97RNF2_18974828_ChIP-Seq_MESCs_Mouse0.80850904
98SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.80610066
99HNFA_21074721_ChIP-Seq_CACO-2_Human0.80016649
100FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.79719592
101CLOCK_20551151_ChIP-Seq_293T_Human0.78148168
102KDM2B_26808549_Chip-Seq_K562_Human0.78025061
103SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.77833013
104FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.77680002
105STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.76854534
106GATA6_25053715_ChIP-Seq_YYC3_Human0.76251254
107PPARA_22158963_ChIP-Seq_LIVER_Mouse0.75901190
108SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.75403741
109JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.75150606
110NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.74313589
111RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.74241517
112SMAD4_21741376_ChIP-Seq_ESCs_Human0.74156410
113RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.73850553
114RBPJ_21746931_ChIP-Seq_IB4_Human0.73097513
115E2F1_20622854_ChIP-Seq_HELA_Human0.73060329
116NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.71844289
117NRF2_20460467_ChIP-Seq_MEFs_Mouse0.71844289
118P68_20966046_ChIP-Seq_HELA_Human0.71784033
119JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.71506481
120TP53_16413492_ChIP-PET_HCT116_Human0.69637535
121GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.67676261
122ELK3_25401928_ChIP-Seq_HUVEC_Human0.66775408
123FOXM1_26456572_ChIP-Seq_MCF-7_Human0.65017899
124FOXA1_25552417_ChIP-Seq_VCAP_Human0.64896571
125AUTS2_25519132_ChIP-Seq_293T-REX_Human0.62416954
126MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.62230720
127PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.61250225
128PIAS1_25552417_ChIP-Seq_VCAP_Human0.60485546
129TBX20_22080862_ChIP-Seq_HEART_Mouse0.59841125
130TBX20_22328084_ChIP-Seq_HEART_Mouse0.59841125

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier8.55825512
2MP0005275_abnormal_skin_tensile7.77038165
3MP0005501_abnormal_skin_physiology5.13085706
4MP0002254_reproductive_system_inflammat4.21925250
5MP0000579_abnormal_nail_morphology4.14969384
6MP0003941_abnormal_skin_development3.79030884
7MP0010234_abnormal_vibrissa_follicle3.73656055
8MP0002060_abnormal_skin_morphology3.72900466
9MP0001216_abnormal_epidermal_layer3.47687446
10MP0010771_integument_phenotype3.22691622
11MP0004947_skin_inflammation3.18858333
12MP0002098_abnormal_vibrissa_morphology3.08110818
13MP0000647_abnormal_sebaceous_gland2.93457156
14MP0004381_abnormal_hair_follicle2.90710645
15MP0003705_abnormal_hypodermis_morpholog2.90583672
16MP0000383_abnormal_hair_follicle2.67992333
17MP0005451_abnormal_body_composition2.45218837
18MP0000467_abnormal_esophagus_morphology2.29531067
19MP0003453_abnormal_keratinocyte_physiol2.27522442
20MP0010678_abnormal_skin_adnexa2.25902481
21MP0001188_hyperpigmentation2.03588109
22MP0002009_preneoplasia2.00008500
23MP0000377_abnormal_hair_follicle1.96550087
24MP0000427_abnormal_hair_cycle1.90197156
25MP0009931_abnormal_skin_appearance1.87671626
26MP0001346_abnormal_lacrimal_gland1.75707007
27MP0000762_abnormal_tongue_morphology1.75021632
28MP0001243_abnormal_dermal_layer1.66800276
29MP0001191_abnormal_skin_condition1.63275780
30MP0004185_abnormal_adipocyte_glucose1.63257506
31MP0000566_synostosis1.54977425
32MP0000367_abnormal_coat/_hair1.52773906
33MP0000015_abnormal_ear_pigmentation1.49775877
34MP0001851_eye_inflammation1.46591729
35MP0005174_abnormal_tail_pigmentation1.35928209
36MP0003566_abnormal_cell_adhesion1.31323003
37MP0004885_abnormal_endolymph1.26344500
38MP0003878_abnormal_ear_physiology1.20647413
39MP0005377_hearing/vestibular/ear_phenot1.20647413
40MP0002234_abnormal_pharynx_morphology1.18818406
41MP0002006_tumorigenesis1.10639268
42MP0002877_abnormal_melanocyte_morpholog1.07944606
43MP0003191_abnormal_cellular_cholesterol0.97551857
44MP0002166_altered_tumor_susceptibility0.97296696
45MP0003011_delayed_dark_adaptation0.96618115
46MP0003763_abnormal_thymus_physiology0.95863504
47MP0000750_abnormal_muscle_regeneration0.95022971
48MP0001340_abnormal_eyelid_morphology0.90957372
49MP0002095_abnormal_skin_pigmentation0.82621005
50MP0002163_abnormal_gland_morphology0.78093264
51MP0003315_abnormal_perineum_morphology0.73086998
52MP0003136_yellow_coat_color0.72818829
53MP0002177_abnormal_outer_ear0.69728054
54MP0005075_abnormal_melanosome_morpholog0.67430817
55MP0005409_darkened_coat_color0.66273542
56MP0009780_abnormal_chondrocyte_physiolo0.65483950
57MP0005023_abnormal_wound_healing0.65327650
58MP0001784_abnormal_fluid_regulation0.64315416
59MP0003300_gastrointestinal_ulcer0.62894509
60MP0001984_abnormal_olfaction0.62205098
61MP0000627_abnormal_mammary_gland0.60790940
62MP0009053_abnormal_anal_canal0.57000357
63MP0001849_ear_inflammation0.53227793
64MP0000465_gastrointestinal_hemorrhage0.51791680
65MP0003755_abnormal_palate_morphology0.50672201
66MP0010030_abnormal_orbit_morphology0.50375991
67MP0005666_abnormal_adipose_tissue0.48974792
68MP0000470_abnormal_stomach_morphology0.48782350
69MP0009672_abnormal_birth_weight0.48378644
70MP0004019_abnormal_vitamin_homeostasis0.45829806
71MP0008438_abnormal_cutaneous_collagen0.44617422
72MP0008961_abnormal_basal_metabolism0.44202934
73MP0004782_abnormal_surfactant_physiolog0.43003232
74MP0009333_abnormal_splenocyte_physiolog0.42495216
75MP0008789_abnormal_olfactory_epithelium0.41999440
76MP0000613_abnormal_salivary_gland0.40228348
77MP0000537_abnormal_urethra_morphology0.39590988
78MP0000751_myopathy0.38302933
79MP0002111_abnormal_tail_morphology0.37976576
80MP0002148_abnormal_hypersensitivity_rea0.36395902
81MP0010352_gastrointestinal_tract_polyps0.35847369
82MP0009384_cardiac_valve_regurgitation0.35561833
83MP0005499_abnormal_olfactory_system0.34648771
84MP0005394_taste/olfaction_phenotype0.34648771
85MP0000759_abnormal_skeletal_muscle0.34206021
86MP0001177_atelectasis0.34130965
87MP0005379_endocrine/exocrine_gland_phen0.33450133
88MP0001666_abnormal_nutrient_absorption0.32906981
89MP0000538_abnormal_urinary_bladder0.32338746
90MP0005076_abnormal_cell_differentiation0.32180648
91MP0000372_irregular_coat_pigmentation0.31888481
92MP0005257_abnormal_intraocular_pressure0.31623688
93MP0004484_altered_response_of0.31524851
94MP0005388_respiratory_system_phenotype0.30959738
95MP0002133_abnormal_respiratory_system0.30959738
96MP0002971_abnormal_brown_adipose0.30290607
97MP0004264_abnormal_extraembryonic_tissu0.29624346
98MP0002106_abnormal_muscle_physiology0.28749190
99MP0003448_altered_tumor_morphology0.28278983
100MP0003329_amyloid_beta_deposits0.28116428
101MP0000749_muscle_degeneration0.27272039
102MP0000747_muscle_weakness0.26257584
103MP0004087_abnormal_muscle_fiber0.25894973
104MP0004130_abnormal_muscle_cell0.25653873
105MP0009379_abnormal_foot_pigmentation0.25523194
106MP0005620_abnormal_muscle_contractility0.25222493
107MP0000685_abnormal_immune_system0.24118259
108MP0003638_abnormal_response/metabolism_0.23530347
109MP0003950_abnormal_plasma_membrane0.23435558
110MP0001270_distended_abdomen0.22517448
111MP0002233_abnormal_nose_morphology0.21847252
112MP0001348_abnormal_lacrimal_gland0.21647468
113MP0000432_abnormal_head_morphology0.21503394
114MP0001186_pigmentation_phenotype0.21244503
115MP0005508_abnormal_skeleton_morphology0.20481517
116MP0002090_abnormal_vision0.20017890
117MP0003866_abnormal_defecation0.19922856
118MP0005375_adipose_tissue_phenotype0.19890435
119MP0004883_abnormal_blood_vessel0.19630606
120MP0001299_abnormal_eye_distance/0.19211414
121MP0008004_abnormal_stomach_pH0.18913942
122MP0002282_abnormal_trachea_morphology0.18363176
123MP0000428_abnormal_craniofacial_morphol0.18337875
124MP0005647_abnormal_sex_gland0.17685500
125MP0004197_abnormal_fetal_growth/weight/0.16509532
126MP0005503_abnormal_tendon_morphology0.15984099
127MP0002697_abnormal_eye_size0.15517668
128MP0003828_pulmonary_edema0.13538025
129MP0000462_abnormal_digestive_system0.13162001
130MP0005171_absent_coat_pigmentation0.12966340
131MP0001958_emphysema0.12537254
132MP0004272_abnormal_basement_membrane0.12325512
133MP0006138_congestive_heart_failure0.11773444
134MP0005193_abnormal_anterior_eye0.09884097
135MP0001756_abnormal_urination0.09684142
136MP0000569_abnormal_digit_pigmentation0.08733433

Predicted human phenotypes

RankGene SetZ-score
1Increased IgE level (HP:0003212)7.97946421
2Hypotrichosis (HP:0001006)7.95412384
3Conjunctival hamartoma (HP:0100780)7.93517065
4Palmoplantar hyperkeratosis (HP:0000972)7.27110148
5Plantar hyperkeratosis (HP:0007556)7.23649430
6Palmar hyperkeratosis (HP:0010765)6.84930574
7Erythema (HP:0010783)6.28660712
8Erythroderma (HP:0001019)5.94299655
9Onycholysis (HP:0001806)5.81171779
10Woolly hair (HP:0002224)5.79364248
11Right ventricular cardiomyopathy (HP:0011663)5.59085059
12Abnormality of nail color (HP:0100643)5.29347629
13Congenital ichthyosiform erythroderma (HP:0007431)5.03616602
14Milia (HP:0001056)4.99411606
15Fragile nails (HP:0001808)4.96076617
16Hamartoma of the eye (HP:0010568)4.94262762
17Thick nail (HP:0001805)4.93353969
18Gangrene (HP:0100758)4.58283013
19Pili torti (HP:0003777)4.47691596
20Abnormal blistering of the skin (HP:0008066)4.37557665
21Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.34246463
22Autoimmune hemolytic anemia (HP:0001890)4.15480989
23Nail dystrophy (HP:0008404)3.76584792
24Parakeratosis (HP:0001036)3.67886250
25Hyporeflexia of lower limbs (HP:0002600)3.65632692
26Corneal erosion (HP:0200020)3.63933844
27Areflexia of lower limbs (HP:0002522)3.48106867
28Round ear (HP:0100830)3.48023610
29Palmoplantar keratoderma (HP:0000982)3.46394009
30Lip pit (HP:0100267)3.44958296
31Abnormal hair laboratory examination (HP:0003328)3.39557614
32Absent eyelashes (HP:0000561)3.32061168
33Ventricular tachycardia (HP:0004756)3.24701775
34Hypohidrosis (HP:0000966)3.22362928
35Distal lower limb muscle weakness (HP:0009053)3.18913905
36Ectropion (HP:0000656)3.18164992
37Ridged nail (HP:0001807)3.10277807
38Curly hair (HP:0002212)3.04013198
39Distal arthrogryposis (HP:0005684)2.92889818
40Pruritus (HP:0000989)2.92032191
41Sparse eyelashes (HP:0000653)2.84256086
42Atrophic scars (HP:0001075)2.82713882
43Concave nail (HP:0001598)2.77787947
44Alopecia of scalp (HP:0002293)2.72442445
45Absent hair (HP:0002298)2.67866553
46Stomatitis (HP:0010280)2.63714285
47Increased connective tissue (HP:0009025)2.62777426
48Type 1 muscle fiber predominance (HP:0003803)2.61227365
49Hypergammaglobulinemia (HP:0010702)2.61034585
50Muscle fiber inclusion bodies (HP:0100299)2.57253190
51Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.56342300
52Achilles tendon contracture (HP:0001771)2.54182389
53Nemaline bodies (HP:0003798)2.50233689
54Hamartoma (HP:0010566)2.36620085
55Abnormality of the Achilles tendon (HP:0005109)2.35924768
56Fatigable weakness (HP:0003473)2.30527298
57Abnormality of the neuromuscular junction (HP:0003398)2.30527298
58Advanced eruption of teeth (HP:0006288)2.26137548
59Oligodontia (HP:0000677)2.25034809
60Split foot (HP:0001839)2.24972199
61Ulnar deviation of the wrist (HP:0003049)2.23261938
62Abnormality of secondary sexual hair (HP:0009888)2.23107783
63Abnormality of the axillary hair (HP:0100134)2.23107783
64Abnormality of the labia majora (HP:0012881)2.21499813
65Acanthosis nigricans (HP:0000956)2.20305215
66Calcaneovalgus deformity (HP:0001848)2.18467742
67Muscle fiber splitting (HP:0003555)2.18105611
68Oral leukoplakia (HP:0002745)2.17166467
69Slow-growing hair (HP:0002217)2.15625236
70Abnormality of hair growth rate (HP:0011363)2.15625236
71Conical tooth (HP:0000698)2.14709323
72Brittle hair (HP:0002299)2.13436202
73Furrowed tongue (HP:0000221)2.12303278
74Myopathic facies (HP:0002058)2.11607943
75Lack of skin elasticity (HP:0100679)2.10600553
76Abnormality of the salivary glands (HP:0010286)2.10148381
77Eczematoid dermatitis (HP:0000976)2.10029782
78Exercise-induced myalgia (HP:0003738)2.06512526
79Nasolacrimal duct obstruction (HP:0000579)2.06361319
80Selective tooth agenesis (HP:0001592)2.05570840
81Abnormal pupillary function (HP:0007686)2.03167518
82Laryngomalacia (HP:0001601)2.01658603
83Pustule (HP:0200039)1.99796786
84Duplicated collecting system (HP:0000081)1.99321942
85Fragile skin (HP:0001030)1.98880422
86Melanocytic nevus (HP:0000995)1.98346221
87Deformed tarsal bones (HP:0008119)1.96925783
88Xerostomia (HP:0000217)1.96787446
89Abnormality of permanent molar morphology (HP:0011071)1.95576990
90Abnormality of the dental root (HP:0006486)1.95576990
91Taurodontia (HP:0000679)1.95576990
92Hyperhidrosis (HP:0000975)1.95424032
93Blepharitis (HP:0000498)1.94185351
94Natal tooth (HP:0000695)1.93859984
95Aplasia cutis congenita (HP:0001057)1.89421443
96Malignant hyperthermia (HP:0002047)1.88179407
97Neck muscle weakness (HP:0000467)1.86952170
98Septate vagina (HP:0001153)1.85018126
99Depressed nasal tip (HP:0000437)1.83205813
100Abnormality of molar (HP:0011077)1.83124616
101Abnormality of molar morphology (HP:0011070)1.83124616
102Skin ulcer (HP:0200042)1.80904643
103Anonychia (HP:0001798)1.80690376
104Absent phalangeal crease (HP:0006109)1.79629825
105Popliteal pterygium (HP:0009756)1.78087948
106Aplasia involving bones of the extremities (HP:0009825)1.77298425
107Aplasia involving bones of the upper limbs (HP:0009823)1.77298425
108Aplasia of the phalanges of the hand (HP:0009802)1.77298425
109Sparse scalp hair (HP:0002209)1.77063329
110Neonatal onset (HP:0003623)1.76589629
111Distal lower limb amyotrophy (HP:0008944)1.75182567
112Sudden death (HP:0001699)1.74776316
113Abnormality of the dental pulp (HP:0006479)1.73089800
114Dehydration (HP:0001944)1.69519382
115Abnormality of the renal collecting system (HP:0004742)1.69238041
116Neonatal death (HP:0003811)1.65883926
117Papilloma (HP:0012740)1.64362682
118Verrucae (HP:0200043)1.64362682
119Follicular hyperkeratosis (HP:0007502)1.63766072
120Abnormality of the lacrimal duct (HP:0011481)1.61381860
121Ventricular fibrillation (HP:0001663)1.60513884
122Sepsis (HP:0100806)1.59128302
123Recurrent corneal erosions (HP:0000495)1.57765041
124Axonal loss (HP:0003447)1.57070001
125Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.56397838
126Abnormality of the gastric mucosa (HP:0004295)1.55621781
127Alveolar cell carcinoma (HP:0006519)1.55529675
128Autoamputation (HP:0001218)1.53430995
129Anhidrosis (HP:0000970)1.50873172
130Dry skin (HP:0000958)1.49747010
131Breast hypoplasia (HP:0003187)1.48748714
132Hypoplastic labia majora (HP:0000059)1.48124684
133Dry hair (HP:0011359)1.47434658
134Abnormality of placental membranes (HP:0011409)1.46689134
135Amniotic constriction ring (HP:0009775)1.46689134
136Multifactorial inheritance (HP:0001426)1.46391676
137Carious teeth (HP:0000670)1.46305693
138Hypodontia (HP:0000668)1.46016225
139Segmental peripheral demyelination/remyelination (HP:0003481)1.45467087
140Hypoplasia of dental enamel (HP:0006297)1.45183434
141Exercise-induced muscle cramps (HP:0003710)1.44824286
142Abnormality of the distal phalanges of the toes (HP:0010182)1.44282929
143Abnormality of the nasolacrimal system (HP:0000614)1.44088724

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK35.35988178
2TGFBR15.16438755
3RIPK13.81848164
4FER3.78717178
5MAP3K33.63428868
6MST1R3.61106767
7BCR3.01911125
8BRD42.97931202
9TTN2.81805703
10PIK3CG2.81290317
11EEF2K2.61041543
12SGK2232.35061493
13SGK4942.35061493
14TAOK12.33024198
15MAP3K112.21569644
16MAP2K62.16526209
17DYRK1B2.10527765
18RPS6KB22.07569076
19MAP3K22.02163349
20MAPKAPK51.87183715
21MAP2K31.84416133
22OBSCN1.77703832
23MST41.70771935
24DAPK21.70467706
25FGFR11.67476515
26ERN11.64357179
27NTRK21.55097430
28EPHA21.50751739
29CDK61.42981601
30FGFR21.34782166
31PRPF4B1.33496854
32TRPM71.32474453
33MARK21.26746393
34EPHB21.23771007
35TAOK21.20698643
36MAP3K11.19036071
37TGFBR21.14824576
38CDK41.13951377
39LATS11.13724777
40DYRK31.10230608
41WNK11.09815987
42IKBKB1.08425900
43MAP3K71.04968982
44IRAK11.04964248
45SGK21.03356417
46BLK0.96155377
47STK30.94697501
48MET0.92542867
49ADRBK10.91877065
50CDK120.84719674
51MAPKAPK20.82320505
52PRKD20.82135925
53SGK30.82050849
54STK38L0.81601610
55FGFR40.81078896
56PTK60.80319605
57LRRK20.78253649
58GRK60.77398559
59NME10.76339190
60MOS0.75599598
61MTOR0.75516343
62RIPK40.75403409
63NLK0.74251604
64AKT30.72964547
65PHKG20.72668610
66PHKG10.72668610
67GSK3A0.71862286
68ABL20.71610802
69PBK0.69721009
70STK110.68292082
71GRK70.66993260
72IRAK20.66259831
73EPHA30.65785841
74ITK0.65422230
75TRIB30.62665897
76DMPK0.61562793
77HCK0.60977275
78EPHB10.60751085
79LATS20.60402400
80FGFR30.60057656
81PRKCI0.59308228
82SIK10.59190617
83MAP2K40.58672506
84SGK10.58057474
85MAP3K90.57658785
86MAP4K10.57162807
87DYRK20.57124192
88SMG10.56684658
89PDGFRB0.55896759
90DDR20.55336124
91PIM20.52885731
92MAPK120.51592802
93MINK10.51161697
94TBK10.50677376
95CAMK2G0.50525254
96TYRO30.49973623
97PAK30.48604712
98MAP3K140.47332832
99CDK90.47009201
100TNK20.46915317
101FYN0.45370801
102KIT0.45148527
103PRKD10.45111203
104PKN10.44613091
105PTK20.43921364
106ERBB30.42845619
107CAMK2D0.42129315
108ICK0.40918301
109BMX0.38009391
110RPS6KB10.35440385
111ERBB40.35300827
112MAPK150.34124908
113PDGFRA0.33559078
114CHUK0.33082373
115MAP3K50.32972658
116NEK10.30524645
117EPHA40.29704992
118MAP3K120.29003873
119STK100.28973414
120PRKAA20.28888832
121RET0.28865138
122STK380.27525660
123TAOK30.27495676
124RPS6KA20.27185673
125IKBKE0.27033669
126MAP2K10.26030035
127PRKCE0.26021286
128ABL10.25927326
129STK240.25321165
130CSNK1A10.24626785
131JAK20.24275465
132PRKACA0.23425939
133MAP3K60.23123594
134KSR20.23121334
135SRC0.22917292
136PAK20.22744158
137MAPK90.22736156
138TIE10.22100894
139HIPK20.20750627
140IRAK40.20551011
141CDK30.20271441
142MAPK70.19932354
143ERBB20.18246684
144GRK50.18236137
145MAPK40.17136023
146MAPK110.17101249
147PRKCA0.16901489
148ROCK20.16623764
149MAPK80.16033315
150AURKA0.15765438

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.23980705
2Linoleic acid metabolism_Homo sapiens_hsa005913.22454642
3Fatty acid elongation_Homo sapiens_hsa000623.04065486
4Cyanoamino acid metabolism_Homo sapiens_hsa004602.61531990
5Staphylococcus aureus infection_Homo sapiens_hsa051502.38469563
6Bladder cancer_Homo sapiens_hsa052192.25298662
7Arachidonic acid metabolism_Homo sapiens_hsa005902.23527605
8Phenylalanine metabolism_Homo sapiens_hsa003602.17433684
9Sulfur metabolism_Homo sapiens_hsa009202.17221555
10Circadian rhythm_Homo sapiens_hsa047102.10052769
11Histidine metabolism_Homo sapiens_hsa003402.03430522
12Ether lipid metabolism_Homo sapiens_hsa005651.97487953
13Sphingolipid metabolism_Homo sapiens_hsa006001.96360900
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.75951462
15Renin secretion_Homo sapiens_hsa049241.58769031
16Fat digestion and absorption_Homo sapiens_hsa049751.56800842
17Dorso-ventral axis formation_Homo sapiens_hsa043201.54087981
18VEGF signaling pathway_Homo sapiens_hsa043701.54025275
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.40014821
20Basal cell carcinoma_Homo sapiens_hsa052171.34080420
21GnRH signaling pathway_Homo sapiens_hsa049121.30061475
22Vascular smooth muscle contraction_Homo sapiens_hsa042701.29515690
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.29208928
24Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.27125775
25Choline metabolism in cancer_Homo sapiens_hsa052311.22307537
26Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.20982678
27Non-small cell lung cancer_Homo sapiens_hsa052231.20602922
28Steroid biosynthesis_Homo sapiens_hsa001001.19951910
29Retinol metabolism_Homo sapiens_hsa008301.10341302
30Axon guidance_Homo sapiens_hsa043601.08765724
31Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.06970241
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06065554
33Fatty acid biosynthesis_Homo sapiens_hsa000611.05480530
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.04530399
35Proteoglycans in cancer_Homo sapiens_hsa052050.99568594
36Tyrosine metabolism_Homo sapiens_hsa003500.99469116
37Adherens junction_Homo sapiens_hsa045200.99468863
38Platelet activation_Homo sapiens_hsa046110.98579525
39Tight junction_Homo sapiens_hsa045300.98401138
40Pancreatic secretion_Homo sapiens_hsa049720.96871808
41ECM-receptor interaction_Homo sapiens_hsa045120.94632558
42Oxytocin signaling pathway_Homo sapiens_hsa049210.93229261
43Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.90221787
44Hedgehog signaling pathway_Homo sapiens_hsa043400.90205937
45T cell receptor signaling pathway_Homo sapiens_hsa046600.89458421
46Long-term depression_Homo sapiens_hsa047300.88542462
47Primary immunodeficiency_Homo sapiens_hsa053400.86590770
48Amoebiasis_Homo sapiens_hsa051460.86228000
49Ras signaling pathway_Homo sapiens_hsa040140.84561510
50Hippo signaling pathway_Homo sapiens_hsa043900.81526797
51beta-Alanine metabolism_Homo sapiens_hsa004100.81451367
52Olfactory transduction_Homo sapiens_hsa047400.80850711
53Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.79186853
54Chemical carcinogenesis_Homo sapiens_hsa052040.77333462
55Sphingolipid signaling pathway_Homo sapiens_hsa040710.77133125
56Notch signaling pathway_Homo sapiens_hsa043300.76763666
57Melanogenesis_Homo sapiens_hsa049160.76703701
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.76014615
59Calcium signaling pathway_Homo sapiens_hsa040200.75226378
60Leukocyte transendothelial migration_Homo sapiens_hsa046700.74991816
61Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73541294
62Dilated cardiomyopathy_Homo sapiens_hsa054140.72244786
63PPAR signaling pathway_Homo sapiens_hsa033200.72180027
64Estrogen signaling pathway_Homo sapiens_hsa049150.70475843
65Adipocytokine signaling pathway_Homo sapiens_hsa049200.70415258
66ABC transporters_Homo sapiens_hsa020100.70071254
67Inositol phosphate metabolism_Homo sapiens_hsa005620.69425374
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.68668856
69Gastric acid secretion_Homo sapiens_hsa049710.68261361
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.67291428
71Serotonergic synapse_Homo sapiens_hsa047260.67083697
72Hematopoietic cell lineage_Homo sapiens_hsa046400.66872271
73Glutamatergic synapse_Homo sapiens_hsa047240.65865256
74Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65279684
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.64867387
76Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.63975363
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.63620401
78MicroRNAs in cancer_Homo sapiens_hsa052060.63588401
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59701302
80Salivary secretion_Homo sapiens_hsa049700.59584297
81Aldosterone synthesis and secretion_Homo sapiens_hsa049250.59473547
82Insulin resistance_Homo sapiens_hsa049310.58795206
83MAPK signaling pathway_Homo sapiens_hsa040100.58267332
84ErbB signaling pathway_Homo sapiens_hsa040120.58233269
85Endocytosis_Homo sapiens_hsa041440.56700415
86Phototransduction_Homo sapiens_hsa047440.56101179
87Toxoplasmosis_Homo sapiens_hsa051450.54771271
88Fatty acid degradation_Homo sapiens_hsa000710.54100496
89Fatty acid metabolism_Homo sapiens_hsa012120.53876678
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53234544
91p53 signaling pathway_Homo sapiens_hsa041150.52818981
92Ribosome_Homo sapiens_hsa030100.52570661
93Renal cell carcinoma_Homo sapiens_hsa052110.52447701
94Pertussis_Homo sapiens_hsa051330.49884299
95Circadian entrainment_Homo sapiens_hsa047130.49760953
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47350616
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47211145
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46673715
99Tuberculosis_Homo sapiens_hsa051520.45871171
100Hepatitis C_Homo sapiens_hsa051600.45719567
101Glioma_Homo sapiens_hsa052140.44834099
102Protein digestion and absorption_Homo sapiens_hsa049740.44711488
103Insulin signaling pathway_Homo sapiens_hsa049100.44463477
104Osteoclast differentiation_Homo sapiens_hsa043800.44404889
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44177836
106Vitamin digestion and absorption_Homo sapiens_hsa049770.43340871
107Rap1 signaling pathway_Homo sapiens_hsa040150.43293887
108Nitrogen metabolism_Homo sapiens_hsa009100.43271904
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.42927084
110Glucagon signaling pathway_Homo sapiens_hsa049220.42787124
111Ovarian steroidogenesis_Homo sapiens_hsa049130.42546326
112Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42356001
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41747755
114Long-term potentiation_Homo sapiens_hsa047200.41354117
115Thyroid cancer_Homo sapiens_hsa052160.40519888
116Salmonella infection_Homo sapiens_hsa051320.39460492
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39026607
118Pathways in cancer_Homo sapiens_hsa052000.39018365
119Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38614373
120Collecting duct acid secretion_Homo sapiens_hsa049660.38309357
121Acute myeloid leukemia_Homo sapiens_hsa052210.37494213
122Jak-STAT signaling pathway_Homo sapiens_hsa046300.36976983
123Small cell lung cancer_Homo sapiens_hsa052220.36888186
124Amphetamine addiction_Homo sapiens_hsa050310.34179753
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31502591
126Thyroid hormone signaling pathway_Homo sapiens_hsa049190.28315507
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.27865516
128Focal adhesion_Homo sapiens_hsa045100.27426100
129cGMP-PKG signaling pathway_Homo sapiens_hsa040220.27413547
130cAMP signaling pathway_Homo sapiens_hsa040240.25024263
131Dopaminergic synapse_Homo sapiens_hsa047280.24668391
132Central carbon metabolism in cancer_Homo sapiens_hsa052300.23438227

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