LCE1F

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratinocyte differentiation (GO:0030216)9.41004130
2water homeostasis (GO:0030104)9.31666242
3hemidesmosome assembly (GO:0031581)7.94201651
4skin morphogenesis (GO:0043589)7.74357017
5epidermal cell differentiation (GO:0009913)7.06345296
6detection of other organism (GO:0098543)6.99317565
7intermediate filament organization (GO:0045109)6.72518345
8bundle of His cell to Purkinje myocyte communication (GO:0086069)6.31349852
9long-chain fatty acid biosynthetic process (GO:0042759)6.05783550
10regulation of natural killer cell differentiation (GO:0032823)5.98962524
11glucosamine-containing compound catabolic process (GO:1901072)5.95840287
12epidermis development (GO:0008544)5.71997625
13negative regulation of interferon-gamma production (GO:0032689)5.16529834
14fatty acid elongation (GO:0030497)5.06566730
15fibrinolysis (GO:0042730)4.79153034
16ectoderm development (GO:0007398)4.77534375
17keratinocyte proliferation (GO:0043616)4.53509711
18intermediate filament cytoskeleton organization (GO:0045104)4.47813202
19linoleic acid metabolic process (GO:0043651)4.43135760
20chemical homeostasis within a tissue (GO:0048875)4.42772545
21intermediate filament-based process (GO:0045103)4.33216291
22virion attachment to host cell (GO:0019062)4.31148292
23adhesion of symbiont to host cell (GO:0044650)4.31148292
24skin development (GO:0043588)4.25759431
25phosphatidylcholine acyl-chain remodeling (GO:0036151)4.15848934
26ceramide biosynthetic process (GO:0046513)4.14332760
27detection of external biotic stimulus (GO:0098581)4.06289614
28gap junction assembly (GO:0016264)3.95604633
29lipoxygenase pathway (GO:0019372)3.93088684
30negative regulation of interleukin-17 production (GO:0032700)3.90221382
31positive regulation of cellular amide metabolic process (GO:0034250)3.78045826
32adhesion of symbiont to host (GO:0044406)3.65804851
33phosphatidylserine metabolic process (GO:0006658)3.60501342
34detection of biotic stimulus (GO:0009595)3.46657262
35skeletal muscle adaptation (GO:0043501)3.46130860
36keratinocyte development (GO:0003334)3.28238089
37long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.28143425
38defense response to Gram-negative bacterium (GO:0050829)3.22011195
39regulation of type B pancreatic cell apoptotic process (GO:2000674)3.18939584
40defense response to fungus (GO:0050832)3.15024023
41regulation of transforming growth factor beta1 production (GO:0032908)3.14288931
42cell-substrate junction assembly (GO:0007044)3.14003629
43negative regulation of cell fate specification (GO:0009996)3.12015943
44polarized epithelial cell differentiation (GO:0030859)3.10709865
45retina homeostasis (GO:0001895)3.03513255
46* keratinization (GO:0031424)25.1034436
47cellular response to calcium ion (GO:0071277)2.98940109
48phospholipid catabolic process (GO:0009395)2.96932817
49atrioventricular valve morphogenesis (GO:0003181)2.96271913
50muscle filament sliding (GO:0030049)2.95526647
51actin-myosin filament sliding (GO:0033275)2.95526647
52regulation of skeletal muscle contraction (GO:0014819)2.94408857
53positive regulation of T cell chemotaxis (GO:0010820)2.94155253
54regulation of T cell chemotaxis (GO:0010819)2.94155253
55alditol phosphate metabolic process (GO:0052646)2.93357751
56positive regulation of epidermal cell differentiation (GO:0045606)2.91290882
57negative regulation of muscle hypertrophy (GO:0014741)2.91070034
58lateral sprouting from an epithelium (GO:0060601)2.90837118
59regulation of natural killer cell activation (GO:0032814)2.90361052
60long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.89106071
61regulation of ruffle assembly (GO:1900027)2.83755147
62epithelial cell-cell adhesion (GO:0090136)2.82361609
63tooth mineralization (GO:0034505)2.81598323
64phosphatidylinositol acyl-chain remodeling (GO:0036149)2.80892895
65positive regulation of interleukin-8 secretion (GO:2000484)2.80537983
66fatty-acyl-CoA metabolic process (GO:0035337)2.80184564
67antimicrobial humoral response (GO:0019730)2.79522944
68sequestering of metal ion (GO:0051238)2.76982471
69positive regulation of monocyte chemotaxis (GO:0090026)2.76808908
70fatty-acyl-CoA biosynthetic process (GO:0046949)2.76041546
71eyelid development in camera-type eye (GO:0061029)2.69820838
72regulation of protein localization to cell surface (GO:2000008)2.67718260
73ventricular cardiac muscle cell action potential (GO:0086005)2.66972021
74cytoskeletal anchoring at plasma membrane (GO:0007016)2.65735259
75sphingolipid biosynthetic process (GO:0030148)2.64833771
76epithelium development (GO:0060429)2.63770782
77negative regulation of keratinocyte proliferation (GO:0010839)2.60758806
78epithelial cell differentiation involved in prostate gland development (GO:0060742)2.59767073
79positive regulation of p38MAPK cascade (GO:1900745)2.58962761
80positive regulation of glomerulus development (GO:0090193)2.56464856
81regulation of epidermis development (GO:0045682)2.55746016
82phosphatidylserine acyl-chain remodeling (GO:0036150)2.51352649
83plasma membrane repair (GO:0001778)2.48233971
84regulation of cardioblast differentiation (GO:0051890)2.47501891
85regulation of keratinocyte proliferation (GO:0010837)2.46931075
86actin-mediated cell contraction (GO:0070252)2.46690270
87primary alcohol catabolic process (GO:0034310)2.46599591
88positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.46367470
89regulation of axon regeneration (GO:0048679)2.45326101
90regulation of neuron projection regeneration (GO:0070570)2.45326101
91very long-chain fatty acid metabolic process (GO:0000038)2.44112033
92cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.41151951
93epithelial cell differentiation (GO:0030855)2.40137753
94negative regulation of catenin import into nucleus (GO:0035414)2.38915644
95amino sugar catabolic process (GO:0046348)2.38130064
96phosphatidylglycerol metabolic process (GO:0046471)2.36679161
97regulation of keratinocyte differentiation (GO:0045616)2.36067725
98detection of bacterium (GO:0016045)2.35903051
99negative regulation of cell fate commitment (GO:0010454)2.34829857
100regulation of cholesterol homeostasis (GO:2000188)2.33213247
101regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.32939785
102regulation of epidermal cell differentiation (GO:0045604)2.32505012
103regulation of cholesterol efflux (GO:0010874)2.31956223
104cell wall macromolecule catabolic process (GO:0016998)2.31890338
105cell wall macromolecule metabolic process (GO:0044036)2.31890338
106surfactant homeostasis (GO:0043129)2.30885806
107positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)2.30096125
108regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)2.30096125
109response to UV-B (GO:0010224)2.29426230
110regulation of cell proliferation involved in kidney development (GO:1901722)2.27245694
111positive regulation of keratinocyte differentiation (GO:0045618)2.26897562
112regulation of heart rate by cardiac conduction (GO:0086091)2.26175196
113regulation of hypersensitivity (GO:0002883)2.24228224
114phospholipid efflux (GO:0033700)2.23734841
115negative regulation of stress fiber assembly (GO:0051497)2.23434032
116positive regulation of cholesterol efflux (GO:0010875)2.21442798
117negative regulation of lymphocyte differentiation (GO:0045620)2.21220828
118planar cell polarity pathway involved in neural tube closure (GO:0090179)2.21152161
119hair follicle morphogenesis (GO:0031069)2.20501661
120establishment of planar polarity (GO:0001736)2.20164058
121establishment of tissue polarity (GO:0007164)2.20164058
122cell communication involved in cardiac conduction (GO:0086065)2.19815479
123sphingosine metabolic process (GO:0006670)2.19663982
124regulation of monocyte chemotaxis (GO:0090025)2.19185678
125regulation of interleukin-17 production (GO:0032660)2.17801264
126positive regulation of humoral immune response (GO:0002922)2.17117193
127regulation of skeletal muscle cell differentiation (GO:2001014)2.17019110
128polysaccharide catabolic process (GO:0000272)2.16660866
129positive regulation of epidermis development (GO:0045684)2.16634996
130defense response to Gram-positive bacterium (GO:0050830)2.16096867
131phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.15390788
132negative regulation of blood coagulation (GO:0030195)2.13997536
133negative regulation of hemostasis (GO:1900047)2.13997536
134actin filament-based movement (GO:0030048)2.13151911
135acyl-CoA biosynthetic process (GO:0071616)2.12296468
136thioester biosynthetic process (GO:0035384)2.12296468
137G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.09312306
138positive regulation of cholesterol transport (GO:0032376)2.05271609
139positive regulation of sterol transport (GO:0032373)2.05271609
140lymph vessel development (GO:0001945)2.04255693
141hormone catabolic process (GO:0042447)2.03622349
142phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.02583954
143regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.02464430
144establishment of skin barrier (GO:0061436)19.8033981
145regulation of water loss via skin (GO:0033561)16.9938041
146desmosome organization (GO:0002934)12.0949415
147hair cycle (GO:0042633)11.5292458
148molting cycle (GO:0042303)11.5292458
149multicellular organismal water homeostasis (GO:0050891)11.2383162
150peptide cross-linking (GO:0018149)10.2842611

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.69219282
2* P63_26484246_Chip-Seq_KERATINOCYTES_Human3.46313288
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.86773403
4ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.61083186
5ZNF263_19887448_ChIP-Seq_K562_Human2.56739640
6SOX9_24532713_ChIP-Seq_HFSC_Mouse2.14612651
7SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.03031332
8TP63_17297297_ChIP-ChIP_HaCaT_Human13.5229423
9TRIM28_21343339_ChIP-Seq_HEK293_Human1.87715086
10FOXO3_23340844_ChIP-Seq_DLD1_Human1.87314796
11ESR2_21235772_ChIP-Seq_MCF-7_Human1.85726763
12PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.84396436
13RARG_19884340_ChIP-ChIP_MEFs_Mouse1.83832962
14SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.83314367
15SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.83314367
16ESR1_21235772_ChIP-Seq_MCF-7_Human1.81611079
17GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.77859837
18PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.75956969
19HIF1A_21447827_ChIP-Seq_MCF-7_Human1.68154502
20ERG_20517297_ChIP-Seq_VCAP_Human1.64166080
21ATF3_27146783_Chip-Seq_COLON_Human1.57554944
22TP63_23658742_ChIP-Seq_EP156T_Human1.56292158
23CTCF_20526341_ChIP-Seq_ESCs_Human1.54385114
24TP63_22573176_ChIP-Seq_HFKS_Human1.53155083
25* CTCF_27219007_Chip-Seq_Bcells_Human1.47564320
26TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.47370470
27RACK7_27058665_Chip-Seq_MCF-7_Human1.46607203
28* GATA6_21074721_ChIP-Seq_CACO-2_Human1.45647535
29RXR_22108803_ChIP-Seq_LS180_Human1.44559915
30CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.41629580
31STAT6_21828071_ChIP-Seq_BEAS2B_Human1.36380135
32RUNX1_27514584_Chip-Seq_MCF-7_Human1.35946370
33DNAJC2_21179169_ChIP-ChIP_NT2_Human1.33962840
34GATA3_24758297_ChIP-Seq_MCF-7_Human1.29441732
35UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.28239486
36P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.27854812
37* BCOR_27268052_Chip-Seq_Bcells_Human1.27799817
38CJUN_26792858_Chip-Seq_BT549_Human1.26715918
39KLF5_25053715_ChIP-Seq_YYC3_Human1.24290772
40KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24054459
41LXR_22292898_ChIP-Seq_THP-1_Human1.22855697
42ZNF217_24962896_ChIP-Seq_MCF-7_Human1.22239618
43SOX2_20726797_ChIP-Seq_SW620_Human1.21351568
44ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.21248305
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.20880632
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.16845106
47NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.15995820
48CEBPB_22108803_ChIP-Seq_LS180_Human1.12665859
49TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.12440791
50* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.12056808
51VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.11355061
52AR_21572438_ChIP-Seq_LNCaP_Human1.11238551
53ESR1_20079471_ChIP-ChIP_T-47D_Human1.10665090
54EGR1_19032775_ChIP-ChIP_M12_Human1.10150794
55E2F1_20622854_ChIP-Seq_HELA_Human1.09307872
56CLOCK_20551151_ChIP-Seq_293T_Human1.08217854
57ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.07921637
58FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.05792338
59SA1_27219007_Chip-Seq_ERYTHROID_Human1.05243408
60BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.05189314
61FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.04385923
62BCL6_27268052_Chip-Seq_Bcells_Human1.03344198
63PPAR_26484153_Chip-Seq_NCI-H1993_Human1.02510824
64YY1_22570637_ChIP-Seq_MALME-3M_Human1.00528631
65TP53_20018659_ChIP-ChIP_R1E_Mouse0.98950364
66UBF1/2_26484160_Chip-Seq_HMECs_Human0.98863496
67BCAT_22108803_ChIP-Seq_LS180_Human0.94872867
68P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93730370
69RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.93564675
70CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.92593374
71JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.91799975
72TP53_18474530_ChIP-ChIP_U2OS_Human0.91552897
73P53_21459846_ChIP-Seq_SAOS-2_Human0.91155085
74P68_20966046_ChIP-Seq_HELA_Human0.91076315
75JARID2_20075857_ChIP-Seq_MESCs_Mouse0.91010238
76SPI1_20517297_ChIP-Seq_HL60_Human0.89472350
77FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.89007139
78SOX2_27498859_Chip-Seq_STOMACH_Mouse0.88989474
79NANOG_20526341_ChIP-Seq_ESCs_Human0.88955589
80BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.87592378
81ERG_21242973_ChIP-ChIP_JURKAT_Human0.86918686
82EZH2_27294783_Chip-Seq_ESCs_Mouse0.85784430
83CSB_26484114_Chip-Seq_FIBROBLAST_Human0.84024112
84AHR_22903824_ChIP-Seq_MCF-7_Human0.83962877
85TP53_16413492_ChIP-PET_HCT116_Human0.83947683
86ELK3_25401928_ChIP-Seq_HUVEC_Human0.83909527
87KDM2B_26808549_Chip-Seq_DND41_Human0.83618488
88STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.83240354
89ELF1_20517297_ChIP-Seq_JURKAT_Human0.82081699
90* TAF2_19829295_ChIP-Seq_ESCs_Human0.82027103
91KDM2B_26808549_Chip-Seq_K562_Human0.81167676
92ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.80511970
93JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.80311085
94SMAD4_21741376_ChIP-Seq_ESCs_Human0.80005743
95HNFA_21074721_ChIP-Seq_CACO-2_Human0.79678188
96GATA6_25053715_ChIP-Seq_YYC3_Human0.79236801
97SMC4_20622854_ChIP-Seq_HELA_Human0.79120945
98AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.78782043
99TBX20_22080862_ChIP-Seq_HEART_Mouse0.78132539
100TBX20_22328084_ChIP-Seq_HEART_Mouse0.78132539
101RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.77581701
102GATA3_21867929_ChIP-Seq_TH1_Mouse0.77351237
103CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.77304330
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.76819157
105GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.76799828
106OCT1_27270436_Chip-Seq_PROSTATE_Human0.76790984
107FOXH1_21741376_ChIP-Seq_ESCs_Human0.76579100
108THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.76468637
109TCF4_18268006_ChIP-ChIP_LS174T_Human0.76158302
110CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.75498396
111GATA2_21666600_ChIP-Seq_HMVEC_Human0.75190823
112SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.74970659
113ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.74711134
114JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.73978036
115RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.72728094
116GATA4_25053715_ChIP-Seq_YYC3_Human0.72614916
117RBPJ_21746931_ChIP-Seq_IB4_Human0.71871134
118EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.70448130
119MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.69851763
120Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.67964027
121PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.67629073
122AUTS2_25519132_ChIP-Seq_293T-REX_Human0.65896209
123PPARA_22158963_ChIP-Seq_LIVER_Mouse0.63738308
124NRF2_20460467_ChIP-Seq_MEFs_Mouse0.63596281
125NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.63596281
126FOXM1_26456572_ChIP-Seq_MCF-7_Human0.62185019
127KDM2B_26808549_Chip-Seq_JURKAT_Human0.61901296

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier9.13992367
2MP0005275_abnormal_skin_tensile8.17090666
3MP0005501_abnormal_skin_physiology5.59677782
4MP0000579_abnormal_nail_morphology5.12829160
5MP0003705_abnormal_hypodermis_morpholog3.92223755
6MP0001188_hyperpigmentation3.52386376
7MP0004947_skin_inflammation3.45424793
8MP0010234_abnormal_vibrissa_follicle3.40148486
9MP0002060_abnormal_skin_morphology3.33281942
10MP0001216_abnormal_epidermal_layer3.30661244
11MP0010771_integument_phenotype3.18813284
12MP0000647_abnormal_sebaceous_gland2.93730832
13MP0002254_reproductive_system_inflammat2.90274247
14MP0003941_abnormal_skin_development2.63294498
15MP0002098_abnormal_vibrissa_morphology2.47379901
16MP0000383_abnormal_hair_follicle2.45755596
17MP0004381_abnormal_hair_follicle2.35581494
18MP0000467_abnormal_esophagus_morphology2.35323732
19MP0009379_abnormal_foot_pigmentation2.34192013
20MP0005451_abnormal_body_composition2.23185832
21MP0000427_abnormal_hair_cycle2.18440468
22MP0000377_abnormal_hair_follicle2.18093945
23MP0010678_abnormal_skin_adnexa2.17338155
24MP0003453_abnormal_keratinocyte_physiol2.11923246
25MP0003878_abnormal_ear_physiology1.97422283
26MP0005377_hearing/vestibular/ear_phenot1.97422283
27MP0009931_abnormal_skin_appearance1.84836588
28MP0001243_abnormal_dermal_layer1.84735445
29MP0000762_abnormal_tongue_morphology1.64467038
30MP0003566_abnormal_cell_adhesion1.63623112
31MP0001191_abnormal_skin_condition1.56578486
32MP0002234_abnormal_pharynx_morphology1.51153114
33MP0000367_abnormal_coat/_hair1.40672629
34MP0004185_abnormal_adipocyte_glucose1.36561416
35MP0001851_eye_inflammation1.28311940
36MP0001346_abnormal_lacrimal_gland1.17739140
37MP0003191_abnormal_cellular_cholesterol1.14972203
38MP0002095_abnormal_skin_pigmentation1.12579963
39MP0008438_abnormal_cutaneous_collagen1.11162592
40MP0002177_abnormal_outer_ear0.87219904
41MP0002877_abnormal_melanocyte_morpholog0.86301231
42MP0001784_abnormal_fluid_regulation0.80867662
43MP0009053_abnormal_anal_canal0.79969307
44MP0000015_abnormal_ear_pigmentation0.79957022
45MP0010030_abnormal_orbit_morphology0.78005399
46MP0005023_abnormal_wound_healing0.76885178
47MP0000751_myopathy0.74548903
48MP0001340_abnormal_eyelid_morphology0.74222196
49MP0005409_darkened_coat_color0.73678904
50MP0001849_ear_inflammation0.69774745
51MP0005174_abnormal_tail_pigmentation0.67717543
52MP0000750_abnormal_muscle_regeneration0.66648322
53MP0000749_muscle_degeneration0.65605373
54MP0010352_gastrointestinal_tract_polyps0.64660179
55MP0009780_abnormal_chondrocyte_physiolo0.60243952
56MP0000465_gastrointestinal_hemorrhage0.59730943
57MP0000747_muscle_weakness0.55868943
58MP0009333_abnormal_splenocyte_physiolog0.51912601
59MP0005666_abnormal_adipose_tissue0.49557066
60MP0008004_abnormal_stomach_pH0.49543126
61MP0003755_abnormal_palate_morphology0.49323031
62MP0000759_abnormal_skeletal_muscle0.44413886
63MP0004087_abnormal_muscle_fiber0.44143639
64MP0002138_abnormal_hepatobiliary_system0.43938516
65MP0000627_abnormal_mammary_gland0.42683510
66MP0002106_abnormal_muscle_physiology0.41627589
67MP0000733_abnormal_muscle_development0.41125780
68MP0001177_atelectasis0.40264952
69MP0003763_abnormal_thymus_physiology0.40136963
70MP0004782_abnormal_surfactant_physiolog0.39881316
71MP0003011_delayed_dark_adaptation0.39873711
72MP0001348_abnormal_lacrimal_gland0.38989049
73MP0003329_amyloid_beta_deposits0.38525265
74MP0002006_tumorigenesis0.36779454
75MP0006054_spinal_hemorrhage0.36367568
76MP0003300_gastrointestinal_ulcer0.36197519
77MP0003315_abnormal_perineum_morphology0.35912562
78MP0002166_altered_tumor_susceptibility0.35113674
79MP0002009_preneoplasia0.34796640
80MP0000566_synostosis0.34471104
81MP0002111_abnormal_tail_morphology0.33587946
82MP0005620_abnormal_muscle_contractility0.32319142
83MP0005375_adipose_tissue_phenotype0.31493632
84MP0002133_abnormal_respiratory_system0.29802915
85MP0005388_respiratory_system_phenotype0.29802915
86MP0005369_muscle_phenotype0.29614182
87MP0004197_abnormal_fetal_growth/weight/0.29443250
88MP0004036_abnormal_muscle_relaxation0.29027736
89MP0003638_abnormal_response/metabolism_0.28498433
90MP0004130_abnormal_muscle_cell0.27648278
91MP0003950_abnormal_plasma_membrane0.27124185
92MP0008789_abnormal_olfactory_epithelium0.26979237
93MP0002089_abnormal_postnatal_growth/wei0.26263159
94MP0005257_abnormal_intraocular_pressure0.26204086
95MP0005076_abnormal_cell_differentiation0.25541689
96MP0002971_abnormal_brown_adipose0.25477459
97MP0003448_altered_tumor_morphology0.25318561
98MP0002282_abnormal_trachea_morphology0.25008844
99MP0003385_abnormal_body_wall0.24436011
100MP0009672_abnormal_birth_weight0.24417829
101MP0005499_abnormal_olfactory_system0.24368327
102MP0005394_taste/olfaction_phenotype0.24368327
103MP0005503_abnormal_tendon_morphology0.24244117
104MP0004264_abnormal_extraembryonic_tissu0.24006195
105MP0004043_abnormal_pH_regulation0.22359492
106MP0002896_abnormal_bone_mineralization0.22196141
107MP0000685_abnormal_immune_system0.21703328
108MP0005075_abnormal_melanosome_morpholog0.21092408
109MP0002697_abnormal_eye_size0.20702757
110MP0001299_abnormal_eye_distance/0.20656132
111MP0004272_abnormal_basement_membrane0.20372535
112MP0002108_abnormal_muscle_morphology0.19215798
113MP0005330_cardiomyopathy0.18973264
114MP0005193_abnormal_anterior_eye0.18632613
115MP0001186_pigmentation_phenotype0.18385624
116MP0000858_altered_metastatic_potential0.18153434
117MP0002972_abnormal_cardiac_muscle0.17692946
118MP0002090_abnormal_vision0.17522381
119MP0003436_decreased_susceptibility_to0.17491965
120MP0001984_abnormal_olfaction0.17075205
121MP0000432_abnormal_head_morphology0.16819538
122MP0004885_abnormal_endolymph0.16422217
123MP0008260_abnormal_autophagy0.14193494
124MP0000003_abnormal_adipose_tissue0.14130979
125MP0000569_abnormal_digit_pigmentation0.13644677
126MP0001502_abnormal_circadian_rhythm0.10293711
127MP0003828_pulmonary_edema0.10146210
128MP0008569_lethality_at_weaning0.09434090
129MP0003045_fibrosis0.08936766
130MP0002233_abnormal_nose_morphology0.07978188
131MP0001958_emphysema0.06762669

Predicted human phenotypes

RankGene SetZ-score
1Conjunctival hamartoma (HP:0100780)9.78541494
2Palmoplantar hyperkeratosis (HP:0000972)8.04443888
3Abnormality of nail color (HP:0100643)7.62394982
4Palmar hyperkeratosis (HP:0010765)7.59837849
5Hypotrichosis (HP:0001006)7.43786619
6Plantar hyperkeratosis (HP:0007556)7.34573949
7Erythroderma (HP:0001019)6.80685967
8Erythema (HP:0010783)6.69339605
9Hamartoma of the eye (HP:0010568)6.35433130
10Onycholysis (HP:0001806)6.17115969
11Thick nail (HP:0001805)5.59719475
12Woolly hair (HP:0002224)5.52179606
13Pili torti (HP:0003777)5.40264630
14Abnormality of secondary sexual hair (HP:0009888)5.33678483
15Abnormality of the axillary hair (HP:0100134)5.33678483
16Right ventricular cardiomyopathy (HP:0011663)5.15971882
17Gangrene (HP:0100758)4.87358414
18Congenital ichthyosiform erythroderma (HP:0007431)4.73571398
19Abnormal blistering of the skin (HP:0008066)4.33743140
20Eczematoid dermatitis (HP:0000976)4.09201915
21Fragile nails (HP:0001808)4.07504510
22Milia (HP:0001056)4.01273081
23Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.88258650
24Oral leukoplakia (HP:0002745)3.82792904
25Alopecia of scalp (HP:0002293)3.70651383
26Hypergammaglobulinemia (HP:0010702)3.58953802
27Nail dystrophy (HP:0008404)3.54361102
28Palmoplantar keratoderma (HP:0000982)3.52861805
29Abnormal hair laboratory examination (HP:0003328)3.40851766
30Follicular hyperkeratosis (HP:0007502)3.32176034
31Corneal erosion (HP:0200020)3.27482556
32Absent eyelashes (HP:0000561)3.25462557
33Type 1 muscle fiber predominance (HP:0003803)3.12515945
34Muscle fiber inclusion bodies (HP:0100299)3.09582062
35Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.09460434
36Abnormality of the salivary glands (HP:0010286)3.05459488
37Ectropion (HP:0000656)3.00580622
38Nemaline bodies (HP:0003798)2.98493158
39Absent hair (HP:0002298)2.89962768
40Increased connective tissue (HP:0009025)2.89802868
41Round ear (HP:0100830)2.86021521
42Ventricular tachycardia (HP:0004756)2.85946467
43Hyporeflexia of lower limbs (HP:0002600)2.85232362
44Hypohidrosis (HP:0000966)2.83886322
45Pustule (HP:0200039)2.80277420
46Distal arthrogryposis (HP:0005684)2.76565006
47Sparse scalp hair (HP:0002209)2.76001659
48Hamartoma (HP:0010566)2.68341528
49Papilloma (HP:0012740)2.66943016
50Verrucae (HP:0200043)2.66943016
51Furrowed tongue (HP:0000221)2.64871265
52Sparse eyelashes (HP:0000653)2.61111905
53Atrophic scars (HP:0001075)2.59084652
54Pruritus (HP:0000989)2.58699654
55Ridged nail (HP:0001807)2.54793825
56Myopathic facies (HP:0002058)2.47346991
57Advanced eruption of teeth (HP:0006288)2.45271273
58Curly hair (HP:0002212)2.37459350
59Melanocytic nevus (HP:0000995)2.34973730
60Dehydration (HP:0001944)2.34059708
61Abnormality of placental membranes (HP:0011409)2.28690351
62Amniotic constriction ring (HP:0009775)2.28690351
63Exercise-induced myalgia (HP:0003738)2.26550191
64Autoamputation (HP:0001218)2.25337711
65Ulnar deviation of the wrist (HP:0003049)2.24769447
66Muscle fiber splitting (HP:0003555)2.21842109
67Natal tooth (HP:0000695)2.18839484
68Calcaneovalgus deformity (HP:0001848)2.14697020
69Abnormality of the neuromuscular junction (HP:0003398)2.10851689
70Fatigable weakness (HP:0003473)2.10851689
71Distal lower limb muscle weakness (HP:0009053)2.10536598
72Achilles tendon contracture (HP:0001771)2.07591576
73Areflexia of lower limbs (HP:0002522)2.05092932
74Hyperhidrosis (HP:0000975)2.04713214
75Sepsis (HP:0100806)2.03891750
76Lack of skin elasticity (HP:0100679)2.03049906
77Hypoplastic labia majora (HP:0000059)2.00338061
78Parakeratosis (HP:0001036)2.00116929
79Increased IgE level (HP:0003212)11.4657084
80Difficulty running (HP:0009046)1.97855839
81Lip pit (HP:0100267)1.94546862
82Abnormality of the Achilles tendon (HP:0005109)1.91990810
83Deformed tarsal bones (HP:0008119)1.86917704
84Fragile skin (HP:0001030)1.86413180
85Dry skin (HP:0000958)1.86174331
86Multifactorial inheritance (HP:0001426)1.84963457
87Abnormality of the labia majora (HP:0012881)1.81853009
88Recurrent corneal erosions (HP:0000495)1.80389116
89Absent phalangeal crease (HP:0006109)1.79006172
90Neck muscle weakness (HP:0000467)1.77065215
91Urticaria (HP:0001025)1.76527994
92Laryngomalacia (HP:0001601)1.75503661
93Exercise-induced muscle cramps (HP:0003710)1.74332880
94Skin ulcer (HP:0200042)1.74195397
95Malignant hyperthermia (HP:0002047)1.71506881
96Brittle hair (HP:0002299)1.71346207
97Sudden death (HP:0001699)1.71033744
98Blepharitis (HP:0000498)1.70297178
99Anonychia (HP:0001798)1.70003595
100Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.68404795
101Selective tooth agenesis (HP:0001592)1.67063084
102Autoimmune hemolytic anemia (HP:0001890)1.67007051
103Split foot (HP:0001839)1.66583717
104Abnormality of skeletal muscle fiber size (HP:0012084)1.66268421
105Axonal loss (HP:0003447)1.64200893
106Carious teeth (HP:0000670)1.63122119
107Increased variability in muscle fiber diameter (HP:0003557)1.62701077
108Acanthosis nigricans (HP:0000956)1.61114235
109Ventricular fibrillation (HP:0001663)1.60441113
110Distal lower limb amyotrophy (HP:0008944)1.60239395
111Paralysis (HP:0003470)1.55988413
112Corneal dystrophy (HP:0001131)1.49663730
113Abnormality of the fingernails (HP:0001231)1.47195983
114Conical tooth (HP:0000698)1.46964029
115Scapular winging (HP:0003691)1.46617122
116Xerostomia (HP:0000217)1.45025050
117Segmental peripheral demyelination/remyelination (HP:0003481)1.44716174
118Slow-growing hair (HP:0002217)1.44702047
119Abnormality of hair growth rate (HP:0011363)1.44702047
120Frequent falls (HP:0002359)1.43923029
121Hypoplastic toenails (HP:0001800)1.42519692
122Duplicated collecting system (HP:0000081)1.42181637
123Abnormality of the calcaneus (HP:0008364)1.41050491
124Spinal rigidity (HP:0003306)1.40264333
125Septate vagina (HP:0001153)1.40152562
126Abnormal finger flexion creases (HP:0006143)1.40074359
127Premature rupture of membranes (HP:0001788)1.39657963
128Asthma (HP:0002099)1.38032318
129Everted lower lip vermilion (HP:0000232)1.37513369
130Abnormality of the gastric mucosa (HP:0004295)1.37045529
131Keratoconjunctivitis sicca (HP:0001097)1.36235007
132Neonatal onset (HP:0003623)1.35390080
133Oligodontia (HP:0000677)1.34071466
134Nasolacrimal duct obstruction (HP:0000579)1.33465968
135Fine hair (HP:0002213)1.29297594
136Anhidrosis (HP:0000970)1.27264652
137Generalized hyperpigmentation (HP:0007440)1.26796118
138Neonatal death (HP:0003811)1.26721299
139Abnormality of permanent molar morphology (HP:0011071)1.26291162
140Abnormality of the dental root (HP:0006486)1.26291162
141Taurodontia (HP:0000679)1.26291162
142Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.25935924

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR14.76990057
2TTN4.23735668
3FER4.06993290
4MAPKAPK34.00314084
5FGFR13.30558015
6PIK3CG3.25058423
7MAP3K33.21917174
8MST1R3.15078579
9RIPK13.01373217
10ERN13.00235203
11TAOK12.70410705
12SGK2232.62252873
13SGK4942.62252873
14OBSCN2.59629699
15TRIB32.28606717
16TIE12.22030259
17MAP3K112.16378203
18BCR2.13721606
19MAP2K31.95517684
20EPHA21.94578784
21LATS11.93426212
22MAP3K91.83010913
23GRK61.70126478
24AKT31.67643748
25DYRK1B1.67643649
26EPHB21.66019492
27EEF2K1.58927015
28MAP3K21.57421172
29RPS6KB21.55127887
30WNK11.49115366
31IRAK11.40480181
32MAP2K61.30950608
33PHKG11.25872917
34PHKG21.25872917
35EPHB11.22414743
36CDK61.21081304
37NME11.18375088
38LATS21.15890057
39MAP3K71.12094111
40MET1.08617531
41ADRBK11.06641786
42LRRK21.05881769
43TRPM71.05732064
44IKBKB1.05373224
45CDK121.04749357
46FLT31.03876220
47MARK21.01525484
48IRAK31.01501524
49NTRK21.01479594
50DDR20.96575636
51MAP3K10.94981835
52BRD40.93985992
53MOS0.93798432
54MAPKAPK20.92313042
55PRPF4B0.91402397
56SGK20.90769806
57ABL20.90487474
58MAPK70.90190995
59PTK60.90103063
60BMX0.90022879
61PDGFRB0.89229986
62DAPK20.87993405
63IRAK20.87055679
64IKBKE0.86805561
65MAP2K40.84495628
66NEK10.82781243
67DMPK0.82442837
68MST40.80944403
69STK38L0.80807033
70SGK30.80753433
71PAK30.78974278
72DYRK30.78417608
73PTK20.78035835
74FGFR40.77808901
75MAPKAPK50.76082301
76MTOR0.75009076
77MAP3K60.74475149
78GRK50.73258295
79ERBB30.71321228
80STK30.70538968
81NTRK10.69586671
82EPHA30.68743239
83PKN20.68005249
84STK380.67902986
85FGFR20.65477449
86RPS6KB10.62618544
87PDGFRA0.62311070
88BLK0.62139804
89IRAK40.60610468
90TAOK20.59616442
91GRK10.56439685
92FGR0.55685509
93RPS6KA40.55048474
94PRKD10.53434307
95SGK10.52566899
96KSR20.52014911
97FGFR30.51905251
98CHUK0.50632529
99PKN10.48200839
100MAP2K10.46929841
101GSK3A0.46629988
102JAK30.46013471
103TYRO30.44924505
104MAPK120.44219230
105HCK0.42942462
106ILK0.42402573
107PRKAA20.42139175
108TAOK30.41887795
109PRKCI0.41672526
110NLK0.41591823
111FYN0.41502451
112TYK20.41364782
113STK240.41171492
114MAPK40.40874324
115CDK40.40241708
116LIMK10.39101117
117RPS6KA20.37760578
118TESK10.37535622
119CAMK2G0.37131369
120GRK70.36337341
121PIM20.34637468
122PAK20.34442520
123TNK20.33349560
124ZAP700.32879809
125STK100.31174697
126ERBB40.30563698
127ABL10.30322294
128CDC42BPA0.29603997
129PRKCH0.27905113
130MAPK110.27687443
131RET0.26986756
132ROCK20.26948281
133TGFBR20.26102454
134SIK10.25992435
135MAPK150.24741589
136ITK0.24156844
137SRC0.23748477
138MAP3K120.23521837
139TBK10.22870064
140LMTK20.22181653
141EPHA40.21755849
142MAP3K50.21413501
143CSNK1A10.20291982
144CSK0.19661272
145CAMK1D0.19652902
146ROCK10.17142858
147PAK60.16947798
148PRKD20.16291863
149ICK0.15657667

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid elongation_Homo sapiens_hsa000623.09739521
2alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.05973212
3Linoleic acid metabolism_Homo sapiens_hsa005912.99790390
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.77498520
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.48334673
6Phenylalanine metabolism_Homo sapiens_hsa003602.22176777
7Staphylococcus aureus infection_Homo sapiens_hsa051502.13679881
8Arachidonic acid metabolism_Homo sapiens_hsa005902.01131676
9Ovarian steroidogenesis_Homo sapiens_hsa049131.99105254
10Fat digestion and absorption_Homo sapiens_hsa049751.87387663
11Histidine metabolism_Homo sapiens_hsa003401.87247518
12Bladder cancer_Homo sapiens_hsa052191.84062553
13Circadian rhythm_Homo sapiens_hsa047101.80273645
14GnRH signaling pathway_Homo sapiens_hsa049121.70402890
15Steroid biosynthesis_Homo sapiens_hsa001001.65915638
16Ether lipid metabolism_Homo sapiens_hsa005651.65760362
17VEGF signaling pathway_Homo sapiens_hsa043701.63938129
18Cyanoamino acid metabolism_Homo sapiens_hsa004601.56408252
19ECM-receptor interaction_Homo sapiens_hsa045121.53165936
20Renin secretion_Homo sapiens_hsa049241.45429023
21Vascular smooth muscle contraction_Homo sapiens_hsa042701.41437309
22Phototransduction_Homo sapiens_hsa047441.40002296
23Proteoglycans in cancer_Homo sapiens_hsa052051.28225789
24Choline metabolism in cancer_Homo sapiens_hsa052311.28022691
25Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25605083
26Adherens junction_Homo sapiens_hsa045201.24891932
27Glioma_Homo sapiens_hsa052141.16585692
28Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.15551749
29Olfactory transduction_Homo sapiens_hsa047401.14791936
30Tight junction_Homo sapiens_hsa045301.12897734
31Sphingolipid metabolism_Homo sapiens_hsa006001.12762315
32Tyrosine metabolism_Homo sapiens_hsa003501.11265790
33Gastric acid secretion_Homo sapiens_hsa049711.11200303
34Salivary secretion_Homo sapiens_hsa049701.10605894
35Dilated cardiomyopathy_Homo sapiens_hsa054141.07907682
36Amoebiasis_Homo sapiens_hsa051461.07105536
37Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.05859299
38Oxytocin signaling pathway_Homo sapiens_hsa049211.02787835
39Pertussis_Homo sapiens_hsa051330.99986924
40Melanogenesis_Homo sapiens_hsa049160.99196941
41PPAR signaling pathway_Homo sapiens_hsa033200.98915904
42Basal cell carcinoma_Homo sapiens_hsa052170.97365547
43Long-term depression_Homo sapiens_hsa047300.95372187
44Platelet activation_Homo sapiens_hsa046110.93251803
45Focal adhesion_Homo sapiens_hsa045100.92100554
46Axon guidance_Homo sapiens_hsa043600.91196165
47Leukocyte transendothelial migration_Homo sapiens_hsa046700.88838526
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.87869396
49Non-small cell lung cancer_Homo sapiens_hsa052230.87726749
50Phospholipase D signaling pathway_Homo sapiens_hsa040720.86464300
51Hippo signaling pathway_Homo sapiens_hsa043900.85839285
52NOD-like receptor signaling pathway_Homo sapiens_hsa046210.84271001
53Ras signaling pathway_Homo sapiens_hsa040140.83534095
54Fatty acid biosynthesis_Homo sapiens_hsa000610.82098899
55Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81406600
56Long-term potentiation_Homo sapiens_hsa047200.80439446
57Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.79764088
58Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.78523052
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78439070
60Acute myeloid leukemia_Homo sapiens_hsa052210.77326525
61Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.74627051
62Estrogen signaling pathway_Homo sapiens_hsa049150.74188373
63Renal cell carcinoma_Homo sapiens_hsa052110.74127305
64Sulfur metabolism_Homo sapiens_hsa009200.73877513
65Insulin resistance_Homo sapiens_hsa049310.73533255
66Chemical carcinogenesis_Homo sapiens_hsa052040.71607235
67Calcium signaling pathway_Homo sapiens_hsa040200.69268340
68Aldosterone synthesis and secretion_Homo sapiens_hsa049250.69029403
69ABC transporters_Homo sapiens_hsa020100.68760089
70Pancreatic secretion_Homo sapiens_hsa049720.67864108
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67405282
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.67356261
73MicroRNAs in cancer_Homo sapiens_hsa052060.65459660
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64409054
75Glucagon signaling pathway_Homo sapiens_hsa049220.64163345
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.64066001
77Rap1 signaling pathway_Homo sapiens_hsa040150.63221128
78Toxoplasmosis_Homo sapiens_hsa051450.63041899
79Glutamatergic synapse_Homo sapiens_hsa047240.62977138
80Retinol metabolism_Homo sapiens_hsa008300.62665104
81Nitrogen metabolism_Homo sapiens_hsa009100.62540467
82beta-Alanine metabolism_Homo sapiens_hsa004100.62492078
83MAPK signaling pathway_Homo sapiens_hsa040100.62387621
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61651917
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.59441105
86Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59111052
87Insulin signaling pathway_Homo sapiens_hsa049100.59099612
88Fatty acid degradation_Homo sapiens_hsa000710.58532219
89Serotonergic synapse_Homo sapiens_hsa047260.56884843
90Protein digestion and absorption_Homo sapiens_hsa049740.56335699
91AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55309767
92Endocytosis_Homo sapiens_hsa041440.54976562
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.54870425
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.54782152
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.51851563
96Salmonella infection_Homo sapiens_hsa051320.50546291
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50355339
98Hedgehog signaling pathway_Homo sapiens_hsa043400.50302439
99Inositol phosphate metabolism_Homo sapiens_hsa005620.50046962
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.50008367
101Thyroid cancer_Homo sapiens_hsa052160.47954548
102Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47729609
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47234307
104Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.46560441
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.46216645
106Tuberculosis_Homo sapiens_hsa051520.45944478
107Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45294411
108Circadian entrainment_Homo sapiens_hsa047130.45223643
109Small cell lung cancer_Homo sapiens_hsa052220.45006851
110Central carbon metabolism in cancer_Homo sapiens_hsa052300.44376118
111Dorso-ventral axis formation_Homo sapiens_hsa043200.43868230
112p53 signaling pathway_Homo sapiens_hsa041150.43858572
113Notch signaling pathway_Homo sapiens_hsa043300.43790363
114Fatty acid metabolism_Homo sapiens_hsa012120.42825319
115ErbB signaling pathway_Homo sapiens_hsa040120.40959733
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.40638556
117Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.40087102
118TNF signaling pathway_Homo sapiens_hsa046680.39942735
119Hepatitis C_Homo sapiens_hsa051600.38955963
120HIF-1 signaling pathway_Homo sapiens_hsa040660.38663955
121Pathways in cancer_Homo sapiens_hsa052000.37721760
122RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.36602529
123Arginine biosynthesis_Homo sapiens_hsa002200.36111967
124Malaria_Homo sapiens_hsa051440.32808672
125Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.31872181
126Chronic myeloid leukemia_Homo sapiens_hsa052200.30585021
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.30393394
128Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.29949704
129Shigellosis_Homo sapiens_hsa051310.27200271
130Influenza A_Homo sapiens_hsa051640.25089827
131Amphetamine addiction_Homo sapiens_hsa050310.24968893
132TGF-beta signaling pathway_Homo sapiens_hsa043500.24701366

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