LDB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* negative regulation of erythrocyte differentiation (GO:0045647)5.45363260
2pre-miRNA processing (GO:0031054)4.19933570
3negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.11039770
4positive regulation of histone deacetylation (GO:0031065)4.06480242
5regulation of histone H3-K27 methylation (GO:0061085)3.96366892
6negative regulation of RNA splicing (GO:0033119)3.84370082
7mannose metabolic process (GO:0006013)3.82928709
8regulation of gamma-delta T cell differentiation (GO:0045586)3.79601310
9positive thymic T cell selection (GO:0045059)3.66290444
10negative regulation of histone methylation (GO:0031061)3.64918264
11peptidyl-lysine dimethylation (GO:0018027)3.57931355
12mRNA stabilization (GO:0048255)3.43497057
13RNA stabilization (GO:0043489)3.43497057
14negative regulation of mRNA processing (GO:0050686)3.39809886
15DNA unwinding involved in DNA replication (GO:0006268)3.38782273
16thymic T cell selection (GO:0045061)3.38715701
17heterochromatin organization (GO:0070828)3.37847595
18embryonic process involved in female pregnancy (GO:0060136)3.36965195
19regulation of translational fidelity (GO:0006450)3.34488195
20positive regulation of gamma-delta T cell activation (GO:0046645)3.33540265
21dosage compensation (GO:0007549)3.27299356
22regulation of gamma-delta T cell activation (GO:0046643)3.23643813
23positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.22695212
243-UTR-mediated mRNA stabilization (GO:0070935)3.17740909
25intracellular estrogen receptor signaling pathway (GO:0030520)3.16262663
26regulation of nucleobase-containing compound transport (GO:0032239)3.14668970
27histone H3-K36 demethylation (GO:0070544)3.14186342
28negative regulation of mRNA metabolic process (GO:1903312)3.13880206
29regulation of NFAT protein import into nucleus (GO:0051532)3.11996981
30antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.09196910
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.09196910
32viral transcription (GO:0019083)3.07339727
33maternal placenta development (GO:0001893)3.06104365
34positive T cell selection (GO:0043368)3.05171125
35protein-DNA complex disassembly (GO:0032986)3.04970598
36nucleosome disassembly (GO:0006337)3.04970598
37positive regulation of protein deacetylation (GO:0090312)3.01426066
38negative regulation of cell killing (GO:0031342)3.00058076
39negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.00058076
40histone lysine demethylation (GO:0070076)2.99251884
41histone H4 deacetylation (GO:0070933)2.98736774
42megakaryocyte development (GO:0035855)2.98064564
43T cell selection (GO:0045058)2.96517115
44response to muramyl dipeptide (GO:0032495)2.94537395
45glucocorticoid receptor signaling pathway (GO:0042921)2.92105221
46positive regulation of gene expression, epigenetic (GO:0045815)2.91639284
47cytoskeletal anchoring at plasma membrane (GO:0007016)2.87354996
48translational termination (GO:0006415)2.86063199
49positive regulation of RNA splicing (GO:0033120)2.85547014
50planar cell polarity pathway involved in neural tube closure (GO:0090179)2.85338405
51histone demethylation (GO:0016577)2.82547175
52negative T cell selection (GO:0043383)2.81064838
53apoptotic process involved in morphogenesis (GO:0060561)2.78929134
54negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.78669145
55Golgi transport vesicle coating (GO:0048200)2.78410647
56COPI coating of Golgi vesicle (GO:0048205)2.78410647
57regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.78176792
58mitotic G1 DNA damage checkpoint (GO:0031571)2.77183243
59positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.76414317
60nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.75514752
61regulation of ARF protein signal transduction (GO:0032012)2.74877813
62natural killer cell differentiation (GO:0001779)2.73920622
63negative thymic T cell selection (GO:0045060)2.72991342
64definitive hemopoiesis (GO:0060216)2.72936168
65nuclear pore complex assembly (GO:0051292)2.72913177
66negative regulation of cell size (GO:0045792)2.72590047
67protein localization to kinetochore (GO:0034501)2.71925402
68modulation by virus of host process (GO:0019054)2.71459217
69regulation of ARF GTPase activity (GO:0032312)2.71117400
70modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.71095729
71modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.71095729
72positive regulation by organism of defense response of other organism involved in symbiotic interact2.71095729
73modulation by symbiont of host immune response (GO:0052553)2.71095729
74positive regulation by symbiont of host defense response (GO:0052509)2.71095729
75modulation by symbiont of host defense response (GO:0052031)2.71095729
76regulation of mRNA stability (GO:0043488)2.70602487
77negative regulation of myotube differentiation (GO:0010832)2.68574143
78spliceosomal tri-snRNP complex assembly (GO:0000244)2.68335383
79positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.67673339
80regulation of chromatin binding (GO:0035561)2.66797876
81mucosal-associated lymphoid tissue development (GO:0048537)2.66258809
82Peyers patch development (GO:0048541)2.66258809
83protein localization to endosome (GO:0036010)2.65900545
84chromatin assembly (GO:0031497)2.65097363
85DNA duplex unwinding (GO:0032508)2.65061199
86alternative mRNA splicing, via spliceosome (GO:0000380)2.64911698
87regulation of translational termination (GO:0006449)2.64307689
88adherens junction assembly (GO:0034333)2.63374588
89establishment of apical/basal cell polarity (GO:0035089)2.62561086
90stress fiber assembly (GO:0043149)2.62439793
91antigen processing and presentation of endogenous antigen (GO:0019883)2.62300078
92histone H2A monoubiquitination (GO:0035518)2.61923608
93erythrocyte maturation (GO:0043249)2.61621302
94modulation by symbiont of host cellular process (GO:0044068)2.61052206
95DNA geometric change (GO:0032392)2.60467354
96positive regulation of SMAD protein import into nucleus (GO:0060391)2.59837167
97histone H4-K16 acetylation (GO:0043984)2.59727625
98regulation of hippo signaling (GO:0035330)2.59570018
99regulation of RNA export from nucleus (GO:0046831)2.59541076
100morphogenesis of an endothelium (GO:0003159)2.58840654
101endothelial tube morphogenesis (GO:0061154)2.58840654
102translational elongation (GO:0006414)2.58545156
103protoporphyrinogen IX metabolic process (GO:0046501)2.57679114
104regulation of histone H3-K9 methylation (GO:0051570)2.57393896
105nuclear pore organization (GO:0006999)2.56711007
106erythrocyte development (GO:0048821)2.54638071
107negative regulation of histone modification (GO:0031057)2.53393218
108regulation of RNA stability (GO:0043487)2.53306212
109trophectodermal cell differentiation (GO:0001829)2.53161148
110positive regulation of B cell differentiation (GO:0045579)2.52188391
111polarized epithelial cell differentiation (GO:0030859)2.51672535
112regulation of early endosome to late endosome transport (GO:2000641)2.51221774
113ribosomal small subunit assembly (GO:0000028)2.51118616
114regulation of sister chromatid cohesion (GO:0007063)2.48915737
115peptidyl-arginine omega-N-methylation (GO:0035247)2.48659261
116detection of bacterium (GO:0016045)2.46889145
117positive regulation of blood vessel endothelial cell migration (GO:0043536)2.46748690
118negative regulation of gene expression, epigenetic (GO:0045814)2.45890360
119protein dealkylation (GO:0008214)2.45739020
120protein demethylation (GO:0006482)2.45739020
121epithelial cell differentiation involved in prostate gland development (GO:0060742)2.44953314
122response to laminar fluid shear stress (GO:0034616)2.44671295
123detection of other organism (GO:0098543)2.44491592
124NLS-bearing protein import into nucleus (GO:0006607)2.44418123
125response to epidermal growth factor (GO:0070849)2.44345974
126histone H3-K4 methylation (GO:0051568)2.43355689
127cytoplasmic mRNA processing body assembly (GO:0033962)2.42869620
128mitotic nuclear envelope disassembly (GO:0007077)2.42697909
129histone H4-K12 acetylation (GO:0043983)2.42113834
130mitotic G1/S transition checkpoint (GO:0044819)2.42054078
131leukocyte aggregation (GO:0070486)2.41284527
132histone H4-K5 acetylation (GO:0043981)2.40881507
133histone H4-K8 acetylation (GO:0043982)2.40881507
134histone H3 deacetylation (GO:0070932)2.40690385
135cell-substrate adherens junction assembly (GO:0007045)2.40522083
136focal adhesion assembly (GO:0048041)2.40522083
137regulation of response to osmotic stress (GO:0047484)2.39497621
138poly(A)+ mRNA export from nucleus (GO:0016973)2.38717864
139regulation of extracellular matrix disassembly (GO:0010715)2.38348121
140histone H3-K9 demethylation (GO:0033169)2.38229429
141response to interleukin-15 (GO:0070672)2.38021419
142cell-substrate junction assembly (GO:0007044)2.36996560
143G1 DNA damage checkpoint (GO:0044783)2.36865572
144regulation of leukocyte degranulation (GO:0043300)2.36688603
145regulation of histone H3-K4 methylation (GO:0051569)2.36604042
146B cell receptor signaling pathway (GO:0050853)2.36297569
147atrioventricular valve morphogenesis (GO:0003181)2.35815479
148translational initiation (GO:0006413)2.34591032
149JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.34112303
150positive regulation of granulocyte differentiation (GO:0030854)2.33801613
151positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.33784127
152protein complex disassembly (GO:0043241)2.33705204
153negative regulation of glial cell proliferation (GO:0060253)2.33693580
154semaphorin-plexin signaling pathway (GO:0071526)2.33668414
155membrane disassembly (GO:0030397)2.33575271
156nuclear envelope disassembly (GO:0051081)2.33575271
157sister chromatid segregation (GO:0000819)2.33403034
158cellular response to epidermal growth factor stimulus (GO:0071364)2.32038660
159histone H3-K4 trimethylation (GO:0080182)2.31833654

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.05501068
2* MYC_22102868_ChIP-Seq_BL_Human4.21365564
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.61863340
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.47560577
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.30101447
6VDR_21846776_ChIP-Seq_THP-1_Human2.97009299
7* TCF7_22412390_ChIP-Seq_EML_Mouse2.61307556
8* KDM2B_26808549_Chip-Seq_DND41_Human2.56104711
9* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.40397982
10* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.35971909
11KDM2B_26808549_Chip-Seq_SUP-B15_Human2.35363580
12* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.34830451
13TP63_17297297_ChIP-ChIP_HaCaT_Human2.29872924
14* ELK3_25401928_ChIP-Seq_HUVEC_Human2.24668767
15TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.07751146
16STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.04226779
17UTX_26944678_Chip-Seq_JUKART_Human2.03870403
18* MAF_26560356_Chip-Seq_TH1_Human2.00272927
19STAT6_21828071_ChIP-Seq_BEAS2B_Human1.93910125
20CIITA_25753668_ChIP-Seq_RAJI_Human1.88466037
21* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.80331627
22LXR_22292898_ChIP-Seq_THP-1_Human1.79804279
23* KDM2B_26808549_Chip-Seq_JURKAT_Human1.76696277
24* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.72898477
25* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.70025819
26* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.64863593
27SCL_19346495_ChIP-Seq_HPC-7_Human1.64225030
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63379543
29GATA1_22025678_ChIP-Seq_K562_Human1.58697733
30VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.57284352
31VDR_24763502_ChIP-Seq_THP-1_Human1.56586986
32E2F4_17652178_ChIP-ChIP_JURKAT_Human1.56120238
33KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.56007459
34SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.53743216
35MYC_18555785_ChIP-Seq_MESCs_Mouse1.53057614
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.52778213
37RACK7_27058665_Chip-Seq_MCF-7_Human1.49107301
38FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.48295035
39ZNF263_19887448_ChIP-Seq_K562_Human1.47992278
40MAF_26560356_Chip-Seq_TH2_Human1.46553509
41NCOR1_26117541_ChIP-Seq_K562_Human1.46014008
42* GATA1_19941827_ChIP-Seq_MEL_Mouse1.44789412
43NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.41017299
44CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.38892388
45DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.38875562
46* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.38785531
47KDM2B_26808549_Chip-Seq_K562_Human1.37232090
48* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.36618154
49* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.36211025
50* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.35897513
51MYB_26560356_Chip-Seq_TH2_Human1.35337482
52MYB_26560356_Chip-Seq_TH1_Human1.34145694
53WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.33695917
54RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.32203495
55CLOCK_20551151_ChIP-Seq_293T_Human1.32056192
56TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32055070
57DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.31125348
58MYB_21317192_ChIP-Seq_ERMYB_Mouse1.30373089
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28862256
60SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.28375601
61XRN2_22483619_ChIP-Seq_HELA_Human1.28020286
62STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.27564996
63* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26891136
64RUNX1_22412390_ChIP-Seq_EML_Mouse1.25652354
65FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.25626413
66GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24886756
67MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.24534197
68ATF3_27146783_Chip-Seq_COLON_Human1.23076774
69BRD4_27068464_Chip-Seq_AML-cells_Mouse1.22811607
70ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.21136213
71* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.19090756
72TP63_19390658_ChIP-ChIP_HaCaT_Human1.18540394
73EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.18402188
74CREB1_26743006_Chip-Seq_LNCaP_Human1.16653206
75UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.16169786
76MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.15605653
77SMC4_20622854_ChIP-Seq_HELA_Human1.15102807
78SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.14627801
79E2F1_21310950_ChIP-Seq_MCF-7_Human1.13803169
80* P68_20966046_ChIP-Seq_HELA_Human1.12871930
81* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.12510325
82HIF1A_21447827_ChIP-Seq_MCF-7_Human1.11333997
83NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10411187
84* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09219015
85ESR2_21235772_ChIP-Seq_MCF-7_Human1.08778223
86* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.08719876
87ELF1_20517297_ChIP-Seq_JURKAT_Human1.08552347
88STAT3_1855785_ChIP-Seq_MESCs_Mouse1.08172422
89CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.07531332
90FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.06948108
91GATA1_22383799_ChIP-Seq_G1ME_Mouse1.06079791
92SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06074635
93TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05919760
94CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05648663
95EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05505950
96CHD1_26751641_Chip-Seq_LNCaP_Human1.04830321
97ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03397305
98* NANOG_21062744_ChIP-ChIP_HESCs_Human1.03233968
99MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.02875123
100TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.02559618
101TET1_21451524_ChIP-Seq_MESCs_Mouse1.02445643
102* SA1_27219007_Chip-Seq_ERYTHROID_Human1.01692113
103* GATA2_19941826_ChIP-Seq_K562_Human1.01475780
104* KDM5A_27292631_Chip-Seq_BREAST_Human1.01301666
105ERG_21242973_ChIP-ChIP_JURKAT_Human1.00883747
106POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.00547880
107HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99702261
108TP53_22127205_ChIP-Seq_IMR90_Human0.99183728
109RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.97870668
110PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.97662007
111PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96741437
112DNAJC2_21179169_ChIP-ChIP_NT2_Human0.95829980
113THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95430960
114RARG_19884340_ChIP-ChIP_MEFs_Mouse0.94370509
115* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94189814
116* SPI1_23127762_ChIP-Seq_K562_Human0.94054581
117RUNX_20019798_ChIP-Seq_JUKART_Human0.94017469
118GATA2_22383799_ChIP-Seq_G1ME_Mouse0.93986094
119* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.93728739
120GATA1_19941826_ChIP-Seq_K562_Human0.93330204
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.93302562
122DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.93001876
123* SPI1_23547873_ChIP-Seq_NB4_Human0.92929164
124STAT4_19710469_ChIP-ChIP_TH1__Mouse0.92493828

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.62694723
2MP0009278_abnormal_bone_marrow2.77948766
3MP0005076_abnormal_cell_differentiation2.72361688
4MP0010352_gastrointestinal_tract_polyps2.67543282
5MP0005451_abnormal_body_composition2.47274794
6MP0003436_decreased_susceptibility_to2.40519853
7MP0003763_abnormal_thymus_physiology2.26636344
8MP0003300_gastrointestinal_ulcer2.23355693
9MP0008260_abnormal_autophagy2.20317041
10MP0003172_abnormal_lysosome_physiology2.13618282
11MP0004808_abnormal_hematopoietic_stem2.06994920
12MP0001849_ear_inflammation2.05555579
13MP0003111_abnormal_nucleus_morphology2.02156975
14MP0003566_abnormal_cell_adhesion2.01966652
15MP0008961_abnormal_basal_metabolism1.90362271
16MP0005058_abnormal_lysosome_morphology1.89491758
17MP0001545_abnormal_hematopoietic_system1.83780829
18MP0005397_hematopoietic_system_phenotyp1.83780829
19MP0003656_abnormal_erythrocyte_physiolo1.82608399
20MP0000703_abnormal_thymus_morphology1.75950462
21MP0005409_darkened_coat_color1.75690041
22MP0003077_abnormal_cell_cycle1.75027720
23MP0010234_abnormal_vibrissa_follicle1.73069186
24MP0003303_peritoneal_inflammation1.72240492
25MP0000733_abnormal_muscle_development1.70610530
26MP0002009_preneoplasia1.70113610
27MP0004197_abnormal_fetal_growth/weight/1.65562817
28MP0001730_embryonic_growth_arrest1.65156739
29MP0002653_abnormal_ependyma_morphology1.64689964
30MP0010030_abnormal_orbit_morphology1.62124335
31MP0003191_abnormal_cellular_cholesterol1.61276958
32MP0000685_abnormal_immune_system1.60718772
33MP0000350_abnormal_cell_proliferation1.60263197
34MP0004957_abnormal_blastocyst_morpholog1.58661202
35MP0004858_abnormal_nervous_system1.58209323
36MP0004185_abnormal_adipocyte_glucose1.56993165
37MP0010094_abnormal_chromosome_stability1.54544477
38MP0004381_abnormal_hair_follicle1.54392664
39MP0006054_spinal_hemorrhage1.52041641
40MP0002398_abnormal_bone_marrow1.50627653
41MP0000537_abnormal_urethra_morphology1.50449647
42MP0010307_abnormal_tumor_latency1.48620165
43* MP0002084_abnormal_developmental_patter1.42968521
44MP0009053_abnormal_anal_canal1.42127340
45MP0002796_impaired_skin_barrier1.41892181
46* MP0002086_abnormal_extraembryonic_tissu1.41765735
47MP0004264_abnormal_extraembryonic_tissu1.41507418
48MP0001958_emphysema1.39517868
49MP0005023_abnormal_wound_healing1.36528704
50* MP0002085_abnormal_embryonic_tissue1.35480330
51MP0002722_abnormal_immune_system1.32652481
52* MP0005380_embryogenesis_phenotype1.32635430
53* MP0001672_abnormal_embryogenesis/_devel1.32635430
54MP0009333_abnormal_splenocyte_physiolog1.32631744
55MP0002166_altered_tumor_susceptibility1.32551740
56* MP0002088_abnormal_embryonic_growth/wei1.31922214
57MP0002877_abnormal_melanocyte_morpholog1.31596911
58MP0008007_abnormal_cellular_replicative1.31516657
59* MP0003984_embryonic_growth_retardation1.31152498
60* MP0002396_abnormal_hematopoietic_system1.30698812
61MP0001697_abnormal_embryo_size1.29132007
62MP0003693_abnormal_embryo_hatching1.28483071
63MP0003123_paternal_imprinting1.27894814
64MP0003567_abnormal_fetal_cardiomyocyte1.26637185
65MP0000490_abnormal_crypts_of1.26584849
66MP0003828_pulmonary_edema1.25684414
67* MP0002080_prenatal_lethality1.22251154
68MP0008438_abnormal_cutaneous_collagen1.22034153
69MP0001851_eye_inflammation1.20654569
70MP0002925_abnormal_cardiovascular_devel1.19579022
71MP0002419_abnormal_innate_immunity1.18850988
72MP0005464_abnormal_platelet_physiology1.16934806
73MP0000465_gastrointestinal_hemorrhage1.16553557
74MP0000689_abnormal_spleen_morphology1.16159160
75MP0009931_abnormal_skin_appearance1.15833084
76MP0003115_abnormal_respiratory_system1.15363140
77MP0001348_abnormal_lacrimal_gland1.15314937
78MP0002089_abnormal_postnatal_growth/wei1.13879744
79MP0001915_intracranial_hemorrhage1.11669477
80MP0004947_skin_inflammation1.11002973
81MP0005083_abnormal_biliary_tract1.10066447
82MP0008770_decreased_survivor_rate1.10012405
83MP0005025_abnormal_response_to1.08401106
84MP0005275_abnormal_skin_tensile1.06856400
85MP0002019_abnormal_tumor_incidence1.05430775
86MP0005621_abnormal_cell_physiology1.05224931
87MP0000678_abnormal_parathyroid_gland1.03449185
88MP0003279_aneurysm1.03126580
89MP0001800_abnormal_humoral_immune1.02278578
90MP0005000_abnormal_immune_tolerance1.01294572
91MP0002249_abnormal_larynx_morphology0.99952465
92MP0004233_abnormal_muscle_weight0.99389345
93MP0000716_abnormal_immune_system0.99331014
94* MP0000428_abnormal_craniofacial_morphol0.99154958
95MP0005623_abnormal_meninges_morphology0.98956677
96MP0002429_abnormal_blood_cell0.98509003
97MP0003935_abnormal_craniofacial_develop0.98487249
98MP0010630_abnormal_cardiac_muscle0.98323144
99MP0006138_congestive_heart_failure0.97775825
100MP0005375_adipose_tissue_phenotype0.93389464
101MP0002092_abnormal_eye_morphology0.93378952
102MP0009672_abnormal_birth_weight0.93227843
103MP0002998_abnormal_bone_remodeling0.93204540
104MP0003121_genomic_imprinting0.92380247
105MP0005666_abnormal_adipose_tissue0.92319584
106MP0009703_decreased_birth_body0.91076714
107MP0003453_abnormal_keratinocyte_physiol0.90803417
108MP0001533_abnormal_skeleton_physiology0.90623218
109MP0001784_abnormal_fluid_regulation0.90347198
110MP0002932_abnormal_joint_morphology0.89854000
111MP0000751_myopathy0.89049568
112MP0010155_abnormal_intestine_physiology0.88108632
113MP0003866_abnormal_defecation0.87951512
114MP0008057_abnormal_DNA_replication0.87769296
115MP0000313_abnormal_cell_death0.87765633
116MP0003283_abnormal_digestive_organ0.87505362
117MP0002405_respiratory_system_inflammati0.87251629
118* MP0000266_abnormal_heart_morphology0.86895292
119MP0000477_abnormal_intestine_morphology0.86764578
120MP0000858_altered_metastatic_potential0.85072107
121MP0000003_abnormal_adipose_tissue0.84534551
122MP0002420_abnormal_adaptive_immunity0.84223405
123MP0003091_abnormal_cell_migration0.84121064
124MP0002006_tumorigenesis0.84108421
125MP0000759_abnormal_skeletal_muscle0.82777177
126MP0002452_abnormal_antigen_presenting0.81991848
127MP0002723_abnormal_immune_serum0.81898950
128MP0001819_abnormal_immune_cell0.81663901
129MP0001835_abnormal_antigen_presentation0.81653320
130MP0005503_abnormal_tendon_morphology0.81339558
131MP0003385_abnormal_body_wall0.81063851
132MP0005501_abnormal_skin_physiology0.80362637
133MP0004087_abnormal_muscle_fiber0.80321839
134MP0000534_abnormal_ureter_morphology0.79596500
135MP0003221_abnormal_cardiomyocyte_apopto0.79115282
136MP0000767_abnormal_smooth_muscle0.77798563
137MP0002060_abnormal_skin_morphology0.77378377
138MP0001790_abnormal_immune_system0.77348980
139MP0005387_immune_system_phenotype0.77348980
140MP0001873_stomach_inflammation0.77305292

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)4.05714759
2Cerebral aneurysm (HP:0004944)3.58211249
3Short 4th metacarpal (HP:0010044)3.38631800
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.38631800
5Obstructive sleep apnea (HP:0002870)3.20820166
6Shallow orbits (HP:0000586)3.12709706
7Abnormality of the fingertips (HP:0001211)3.02759944
8Eczematoid dermatitis (HP:0000976)3.01241354
9Broad face (HP:0000283)3.00843828
10Renal duplication (HP:0000075)2.86686899
11Reticulocytosis (HP:0001923)2.81652884
12Abnormality of the 4th metacarpal (HP:0010012)2.75945085
13Protrusio acetabuli (HP:0003179)2.73129303
14Increased IgE level (HP:0003212)2.70976435
15Insomnia (HP:0100785)2.55837801
16Ependymoma (HP:0002888)2.54919058
17Elfin facies (HP:0004428)2.54514624
18Broad palm (HP:0001169)2.50534472
19Basal cell carcinoma (HP:0002671)2.48846060
20Renovascular hypertension (HP:0100817)2.48652591
21Ulnar bowing (HP:0003031)2.48138692
22Increased density of long bones (HP:0006392)2.44261935
23Metaphyseal cupping (HP:0003021)2.44013243
24Centrally nucleated skeletal muscle fibers (HP:0003687)2.41357735
25Increased connective tissue (HP:0009025)2.38615112
26Ankle contracture (HP:0006466)2.38084604
27Aortic aneurysm (HP:0004942)2.37252526
28Mitral valve prolapse (HP:0001634)2.35634214
29Distal lower limb amyotrophy (HP:0008944)2.34694300
30Increased nuchal translucency (HP:0010880)2.34540101
31Polycythemia (HP:0001901)2.33680027
32Bowel diverticulosis (HP:0005222)2.32608486
33Overriding aorta (HP:0002623)2.32088866
34Selective tooth agenesis (HP:0001592)2.28657617
35Macroorchidism (HP:0000053)2.28364212
36Broad metatarsal (HP:0001783)2.26095038
37Cholecystitis (HP:0001082)2.20453922
38Abnormal gallbladder physiology (HP:0012438)2.20453922
39Bladder diverticulum (HP:0000015)2.20128059
40Genu recurvatum (HP:0002816)2.17649360
41Dilatation of the ascending aorta (HP:0005111)2.11808318
42Cervical subluxation (HP:0003308)2.11163475
43Asymmetry of the thorax (HP:0001555)2.08673319
44Bicuspid aortic valve (HP:0001647)2.08588865
45Abnormality of the astrocytes (HP:0100707)2.07279455
46Astrocytoma (HP:0009592)2.07279455
47Spontaneous hematomas (HP:0007420)2.05927659
48Pointed chin (HP:0000307)2.05180601
49Increased variability in muscle fiber diameter (HP:0003557)2.04897769
50Heterotopia (HP:0002282)2.04284824
51Aneurysm (HP:0002617)2.01949072
52Flat cornea (HP:0007720)1.99684267
53Skin tags (HP:0010609)1.98316893
54Flat acetabular roof (HP:0003180)1.98031049
55Long eyelashes (HP:0000527)1.97789511
56Enlarged penis (HP:0000040)1.96013789
57Neoplasm of the heart (HP:0100544)1.95264721
58Rectal prolapse (HP:0002035)1.95118778
59Colitis (HP:0002583)1.93046722
60High pitched voice (HP:0001620)1.92643429
61Hallux valgus (HP:0001822)1.92362326
62Deviation of the hallux (HP:0010051)1.92325318
63Trigonocephaly (HP:0000243)1.92045648
64Prolonged bleeding time (HP:0003010)1.91284702
65Biconcave vertebral bodies (HP:0004586)1.90584221
66Abnormality of skeletal muscle fiber size (HP:0012084)1.90207999
67Abnormality of the heme biosynthetic pathway (HP:0010472)1.88513367
68Dislocated radial head (HP:0003083)1.88313093
69Pseudobulbar signs (HP:0002200)1.88272570
70Long palpebral fissure (HP:0000637)1.88036259
71T lymphocytopenia (HP:0005403)1.87989638
72Thin bony cortex (HP:0002753)1.87339920
73Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.86711519
74Milia (HP:0001056)1.86702043
75Disproportionate tall stature (HP:0001519)1.86666191
76Papilloma (HP:0012740)1.86665739
77Verrucae (HP:0200043)1.86665739
78Bowel incontinence (HP:0002607)1.86479946
79Annular pancreas (HP:0001734)1.85481277
80Fragile skin (HP:0001030)1.84732823
81Syringomyelia (HP:0003396)1.83355730
82Spinal cord lesions (HP:0100561)1.83355730
83Abnormality of the thoracic spine (HP:0100711)1.83339219
84Gingivitis (HP:0000230)1.82397365
85Thin ribs (HP:0000883)1.81722324
86Malignant gastrointestinal tract tumors (HP:0006749)1.80728741
87Gastrointestinal carcinoma (HP:0002672)1.80728741
88Abnormality of oral frenula (HP:0000190)1.80024952
89Gastrointestinal inflammation (HP:0004386)1.79983792
90Proximal placement of thumb (HP:0009623)1.79156365
91Deviation of the thumb (HP:0009603)1.77820792
92Bowed forearm bones (HP:0003956)1.77528687
93Bowing of the arm (HP:0006488)1.77528687
94Abnormality of reticulocytes (HP:0004312)1.77448103
95Broad thumb (HP:0011304)1.76987341
96Abnormality of the radial head (HP:0003995)1.76558896
97Segmental peripheral demyelination/remyelination (HP:0003481)1.76343553
98Germ cell neoplasia (HP:0100728)1.75054016
99Dysmetric saccades (HP:0000641)1.74745054
100Supernumerary ribs (HP:0005815)1.74204428
101Aortic dissection (HP:0002647)1.74126023
102Interstitial pulmonary disease (HP:0006530)1.73340967
103Neoplasm of the oral cavity (HP:0100649)1.72463688
104Short 5th finger (HP:0009237)1.72271745
105Narrow palate (HP:0000189)1.72232262
106Medulloblastoma (HP:0002885)1.71174025
107Arterial tortuosity (HP:0005116)1.70760543
108Distal lower limb muscle weakness (HP:0009053)1.69948087
109Persistence of primary teeth (HP:0006335)1.69639085
110Subacute progressive viral hepatitis (HP:0006572)1.69341254
111Arnold-Chiari malformation (HP:0002308)1.69151283
112Fibroma (HP:0010614)1.69129657
113Radial bowing (HP:0002986)1.69037279
114Short phalanx of the thumb (HP:0009660)1.68945139
115Abnormality of nail color (HP:0100643)1.68849445
116Abnormal large intestine physiology (HP:0012700)1.67958436
117Distal upper limb amyotrophy (HP:0007149)1.67891039
118Upper limb amyotrophy (HP:0009129)1.67891039
119Abnormality of the diencephalon (HP:0010662)1.67405336
120Fibrous tissue neoplasm (HP:0012316)1.67230616
121Abnormality of T cell number (HP:0011839)1.66053916
122Abnormality of the nasal mucosa (HP:0000433)1.65696968
123Joint laxity (HP:0001388)1.64969464
124Lymphangioma (HP:0100764)1.64654672
125Recurrent abscess formation (HP:0002722)1.63869836
126Lower limb amyotrophy (HP:0007210)1.63543616
127Gastrointestinal infarctions (HP:0005244)1.63456526
128Blue sclerae (HP:0000592)1.63055984
129Vascular tortuosity (HP:0004948)1.63009884
130Vertebral compression fractures (HP:0002953)1.62925199
131Panhypogammaglobulinemia (HP:0003139)1.62817842
132Nonimmune hydrops fetalis (HP:0001790)1.62439563
133Hand muscle atrophy (HP:0009130)1.62203939
134Mitral regurgitation (HP:0001653)1.61969492
135Ankyloglossia (HP:0010296)1.61735640
136Recurrent viral infections (HP:0004429)1.61622746
137Slow saccadic eye movements (HP:0000514)1.61402187
138Abnormal number of incisors (HP:0011064)1.61147681
139Premature rupture of membranes (HP:0001788)1.60950699
140Sparse lateral eyebrow (HP:0005338)1.60738295
141Recurrent bacterial skin infections (HP:0005406)1.60257118
142Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.60146816
143Preauricular skin tag (HP:0000384)1.60138798
144Cellulitis (HP:0100658)1.59282723
145Abnormality of the peritoneum (HP:0002585)1.58865587
146Nasal polyposis (HP:0100582)1.58486201
147Colon cancer (HP:0003003)1.58253309
148Turricephaly (HP:0000262)1.57723413
149Vertebral arch anomaly (HP:0008438)1.57600169
150Abnormality of macrophages (HP:0004311)1.57377143
151Premature skin wrinkling (HP:0100678)1.57289553
152Viral hepatitis (HP:0006562)1.56732399
153Atrophic scars (HP:0001075)1.56629213
154Pustule (HP:0200039)1.56496442
155Abnormality of the distal phalanx of the thumb (HP:0009617)1.55499372
156Hematochezia (HP:0002573)1.55157335
157Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.54467627
158Sacral dimple (HP:0000960)1.54384124
159Obsessive-compulsive behavior (HP:0000722)1.53415625
160Thoracic kyphosis (HP:0002942)1.52939174
161Patellar dislocation (HP:0002999)1.52879729
162Inflammation of the large intestine (HP:0002037)1.52644328
163Neoplasm of striated muscle (HP:0009728)1.52601313
164Advanced eruption of teeth (HP:0006288)1.51121939
165Onion bulb formation (HP:0003383)1.51073792
166Cholelithiasis (HP:0001081)1.49444482
167Wormian bones (HP:0002645)1.48792950
168Abnormality of the calcaneus (HP:0008364)1.48770608

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.91112001
2TRIB34.51925452
3PKN24.11064107
4MAP3K103.92937476
5PRPF4B3.89325811
6SMG12.96630975
7MAP4K12.71261900
8CDK122.68934546
9RIPK42.08954559
10ICK1.83484082
11PTK61.73320700
12PDGFRA1.72571592
13LRRK21.71880302
14ERN11.70486276
15TTN1.70263204
16SIK21.67289815
17NEK21.66688689
18STK101.63429334
19RPS6KB21.57182903
20RIPK11.50200142
21ALK1.48326629
22SIK11.42794896
23TYRO31.38534848
24GRK61.37509146
25MAP3K131.34735121
26FGFR41.31549062
27PAK41.30341529
28PASK1.27566574
29MTOR1.26294657
30BMX1.25225494
31CDK41.22569244
32MAP3K61.22150121
33TGFBR21.22066584
34TAOK11.20048663
35CDC71.18238054
36CDK61.15170669
37ZAP701.12738797
38SIK31.04437482
39JAK31.02808675
40FES1.00134375
41FLT30.99583593
42MAP3K10.98610486
43MAP3K70.97904788
44TGFBR10.96015434
45BRD40.93760187
46PAK20.93164952
47FGFR30.92511237
48PDGFRB0.88954742
49NTRK10.84440187
50MAP3K140.84307514
51DDR20.83903176
52ITK0.83031022
53SCYL20.83015797
54MAP2K30.82855624
55TYK20.82085796
56CAMK1D0.81459523
57BLK0.78055253
58MAP3K30.77989332
59TAOK20.77474204
60MAPK120.77380457
61MAP3K80.77206142
62DMPK0.77150943
63CAMK1G0.76844989
64MAPKAPK30.76295211
65RPS6KA40.75126795
66PIM10.74602359
67LATS10.74503581
68FGFR10.73885329
69HCK0.73665777
70BTK0.72822105
71PRKD20.72155846
72RET0.71855662
73HIPK20.70634366
74CDK70.70611543
75TSSK60.69175599
76DYRK1B0.67934584
77MARK20.67488349
78ILK0.66747201
79PRKCH0.66664986
80NEK10.65901681
81EPHB10.65268357
82CSF1R0.63527695
83FGFR20.62144727
84IRAK40.61933099
85CSK0.61458148
86JAK20.58802857
87PTK20.58781996
88PDPK10.58621955
89CHEK10.58434468
90WNK10.57416455
91TNK20.55864297
92MAPK110.55829963
93CLK10.55183996
94TBK10.54602217
95MAP2K20.52726105
96CDK20.52685887
97MAP3K20.52097102
98ATR0.51717961
99JAK10.51328278
100RPS6KA10.50953359
101RPS6KC10.50431925
102RPS6KL10.50431925
103MAPK70.49217506
104TESK20.49194696
105LCK0.49152691
106RPS6KA20.48988920
107STK40.48833987
108RPS6KA60.47601558
109EPHB20.47455291
110SGK30.47126824
111LATS20.45440353
112STK380.45084463
113EPHA30.42665277
114CAMKK10.41436842
115CHUK0.41340932
116STK30.41060427
117CDC42BPA0.40774610
118CDK90.40655173
119MAP3K110.40609317
120PRKD10.39206662
121PDK10.38807386
122TRPM70.38661205
123MARK30.38650499
124KSR10.37819308
125PRKD30.37088040
126RAF10.36810120
127AKT20.36557060
128FGR0.36556765
129KSR20.35807925
130MAPK100.35639753
131MAPK10.33771806
132SYK0.32588098

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052202.25545653
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.22950848
3Notch signaling pathway_Homo sapiens_hsa043301.98353228
4Primary immunodeficiency_Homo sapiens_hsa053401.90950120
5Other glycan degradation_Homo sapiens_hsa005111.89509012
6Acute myeloid leukemia_Homo sapiens_hsa052211.70002407
7mTOR signaling pathway_Homo sapiens_hsa041501.68505187
8Spliceosome_Homo sapiens_hsa030401.66204146
9Colorectal cancer_Homo sapiens_hsa052101.64348040
10B cell receptor signaling pathway_Homo sapiens_hsa046621.59629263
11Non-small cell lung cancer_Homo sapiens_hsa052231.59170317
12T cell receptor signaling pathway_Homo sapiens_hsa046601.58875309
13Small cell lung cancer_Homo sapiens_hsa052221.55467672
14Lysine degradation_Homo sapiens_hsa003101.55257751
15mRNA surveillance pathway_Homo sapiens_hsa030151.53662992
16Basal cell carcinoma_Homo sapiens_hsa052171.49044612
17Endometrial cancer_Homo sapiens_hsa052131.47443432
18MicroRNAs in cancer_Homo sapiens_hsa052061.46774715
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.41966586
20HTLV-I infection_Homo sapiens_hsa051661.40723856
21Proteoglycans in cancer_Homo sapiens_hsa052051.40270746
22Pancreatic cancer_Homo sapiens_hsa052121.38410391
23Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.36913164
24Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.36295416
25Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.35348370
26AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.35135252
27DNA replication_Homo sapiens_hsa030301.31899551
28VEGF signaling pathway_Homo sapiens_hsa043701.30988653
29Neurotrophin signaling pathway_Homo sapiens_hsa047221.26863714
30Antigen processing and presentation_Homo sapiens_hsa046121.26413101
31Cell cycle_Homo sapiens_hsa041101.24507258
32RNA transport_Homo sapiens_hsa030131.23756304
33Thyroid hormone signaling pathway_Homo sapiens_hsa049191.22851933
34Bladder cancer_Homo sapiens_hsa052191.22292001
35Adherens junction_Homo sapiens_hsa045201.21129859
36Focal adhesion_Homo sapiens_hsa045101.20267552
37Viral myocarditis_Homo sapiens_hsa054161.16456220
38Central carbon metabolism in cancer_Homo sapiens_hsa052301.15868489
39Hippo signaling pathway_Homo sapiens_hsa043901.15638213
40Thyroid cancer_Homo sapiens_hsa052161.15138353
41Inositol phosphate metabolism_Homo sapiens_hsa005621.15023762
42Glioma_Homo sapiens_hsa052141.14703061
43Osteoclast differentiation_Homo sapiens_hsa043801.13952066
44Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.12014122
45Viral carcinogenesis_Homo sapiens_hsa052031.11959001
46GnRH signaling pathway_Homo sapiens_hsa049121.11684893
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.10766566
48Platelet activation_Homo sapiens_hsa046111.10656926
49Base excision repair_Homo sapiens_hsa034101.08510878
50Hepatitis B_Homo sapiens_hsa051611.08109978
51Renal cell carcinoma_Homo sapiens_hsa052111.06667852
52Toxoplasmosis_Homo sapiens_hsa051451.05498007
53Toll-like receptor signaling pathway_Homo sapiens_hsa046201.02194963
54* Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02152853
55Measles_Homo sapiens_hsa051621.01671852
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.99706132
57Mismatch repair_Homo sapiens_hsa034300.99469147
58p53 signaling pathway_Homo sapiens_hsa041150.98307223
59Prolactin signaling pathway_Homo sapiens_hsa049170.98306361
60Herpes simplex infection_Homo sapiens_hsa051680.97906995
61Hepatitis C_Homo sapiens_hsa051600.97245504
62Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.97244833
63Pathways in cancer_Homo sapiens_hsa052000.96833286
64Longevity regulating pathway - mammal_Homo sapiens_hsa042110.96568881
65Insulin resistance_Homo sapiens_hsa049310.94481137
66Malaria_Homo sapiens_hsa051440.93318747
67Apoptosis_Homo sapiens_hsa042100.92444950
68Hedgehog signaling pathway_Homo sapiens_hsa043400.92102009
69Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.91430039
70Prostate cancer_Homo sapiens_hsa052150.89986213
71Estrogen signaling pathway_Homo sapiens_hsa049150.86777410
72Sphingolipid signaling pathway_Homo sapiens_hsa040710.85726499
73FoxO signaling pathway_Homo sapiens_hsa040680.85540023
74TNF signaling pathway_Homo sapiens_hsa046680.85433543
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.85185156
76Ribosome_Homo sapiens_hsa030100.84537745
77Prion diseases_Homo sapiens_hsa050200.83440909
78HIF-1 signaling pathway_Homo sapiens_hsa040660.83429133
79Leishmaniasis_Homo sapiens_hsa051400.83053815
80Regulation of actin cytoskeleton_Homo sapiens_hsa048100.82924582
81ECM-receptor interaction_Homo sapiens_hsa045120.82813939
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.82358357
83Long-term potentiation_Homo sapiens_hsa047200.79252572
84Dorso-ventral axis formation_Homo sapiens_hsa043200.79090347
85Wnt signaling pathway_Homo sapiens_hsa043100.78298208
86Insulin signaling pathway_Homo sapiens_hsa049100.77996303
87Shigellosis_Homo sapiens_hsa051310.77709230
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76843959
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76325349
90Rap1 signaling pathway_Homo sapiens_hsa040150.75767081
91Glycosaminoglycan degradation_Homo sapiens_hsa005310.75245931
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74535181
93Tuberculosis_Homo sapiens_hsa051520.73894724
94Epstein-Barr virus infection_Homo sapiens_hsa051690.72553877
95TGF-beta signaling pathway_Homo sapiens_hsa043500.71028024
96AMPK signaling pathway_Homo sapiens_hsa041520.71022168
97Type II diabetes mellitus_Homo sapiens_hsa049300.70899458
98ErbB signaling pathway_Homo sapiens_hsa040120.70259804
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.70045819
100Chemokine signaling pathway_Homo sapiens_hsa040620.69331037
101Amoebiasis_Homo sapiens_hsa051460.69014658
102Hematopoietic cell lineage_Homo sapiens_hsa046400.68261011
103Endocytosis_Homo sapiens_hsa041440.66949845
104One carbon pool by folate_Homo sapiens_hsa006700.66901035
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.64007324
106MAPK signaling pathway_Homo sapiens_hsa040100.63079775
107RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.62444686
108Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.62084804
109Influenza A_Homo sapiens_hsa051640.61235740
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59940804
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59376711
112Melanogenesis_Homo sapiens_hsa049160.56982983
113Pentose phosphate pathway_Homo sapiens_hsa000300.56559980
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.56159775
115Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55956166
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55102463
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.55024108
118Choline metabolism in cancer_Homo sapiens_hsa052310.54077224
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54019907
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.53990028
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.51484514
122Ras signaling pathway_Homo sapiens_hsa040140.49224444
123Salmonella infection_Homo sapiens_hsa051320.47207366

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