

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.71260242 |
| 2 | proteasome assembly (GO:0043248) | 5.24060499 |
| 3 | regulation of meiosis I (GO:0060631) | 5.08191655 |
| 4 | spindle assembly involved in mitosis (GO:0090307) | 5.06907279 |
| 5 | chaperone-mediated protein transport (GO:0072321) | 4.77858294 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.52871806 |
| 7 | organelle disassembly (GO:1903008) | 4.44806969 |
| 8 | protein neddylation (GO:0045116) | 4.31177200 |
| 9 | rRNA modification (GO:0000154) | 4.24120317 |
| 10 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.18573125 |
| 11 | termination of RNA polymerase III transcription (GO:0006386) | 4.18573125 |
| 12 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.12312811 |
| 13 | ribonucleoprotein complex disassembly (GO:0032988) | 4.09380809 |
| 14 | ATP synthesis coupled proton transport (GO:0015986) | 4.08888030 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.08888030 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.05755452 |
| 17 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.85819160 |
| 18 | maturation of 5.8S rRNA (GO:0000460) | 3.84816894 |
| 19 | synapsis (GO:0007129) | 3.75307251 |
| 20 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.69952958 |
| 21 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.68518692 |
| 22 | maturation of SSU-rRNA (GO:0030490) | 3.66006933 |
| 23 | cullin deneddylation (GO:0010388) | 3.61018441 |
| 24 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.57551245 |
| 25 | ribosomal small subunit assembly (GO:0000028) | 3.54808531 |
| 26 | regulation of DNA endoreduplication (GO:0032875) | 3.53414525 |
| 27 | regulation of response to tumor cell (GO:0002834) | 3.43884550 |
| 28 | positive regulation of response to tumor cell (GO:0002836) | 3.43884550 |
| 29 | positive regulation of immune response to tumor cell (GO:0002839) | 3.43884550 |
| 30 | regulation of immune response to tumor cell (GO:0002837) | 3.43884550 |
| 31 | positive regulation of muscle cell apoptotic process (GO:0010661) | 3.43000678 |
| 32 | rRNA processing (GO:0006364) | 3.40580659 |
| 33 | kynurenine metabolic process (GO:0070189) | 3.38312264 |
| 34 | rRNA metabolic process (GO:0016072) | 3.33866197 |
| 35 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.33162200 |
| 36 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.33162200 |
| 37 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.33008334 |
| 38 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.30122187 |
| 39 | tryptophan catabolic process (GO:0006569) | 3.29714372 |
| 40 | indole-containing compound catabolic process (GO:0042436) | 3.29714372 |
| 41 | indolalkylamine catabolic process (GO:0046218) | 3.29714372 |
| 42 | nucleobase biosynthetic process (GO:0046112) | 3.28583557 |
| 43 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.28448961 |
| 44 | pseudouridine synthesis (GO:0001522) | 3.25220694 |
| 45 | protein K6-linked ubiquitination (GO:0085020) | 3.25081525 |
| 46 | rRNA methylation (GO:0031167) | 3.22441649 |
| 47 | protein deneddylation (GO:0000338) | 3.18833473 |
| 48 | DNA double-strand break processing (GO:0000729) | 3.18094924 |
| 49 | purine nucleobase biosynthetic process (GO:0009113) | 3.17842748 |
| 50 | postreplication repair (GO:0006301) | 3.15241128 |
| 51 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.14866267 |
| 52 | ribosomal large subunit biogenesis (GO:0042273) | 3.14164988 |
| 53 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.08533524 |
| 54 | positive regulation of DNA recombination (GO:0045911) | 3.08384897 |
| 55 | translesion synthesis (GO:0019985) | 3.07981699 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.06136743 |
| 57 | axoneme assembly (GO:0035082) | 3.03466447 |
| 58 | nucleotide transmembrane transport (GO:1901679) | 3.03360283 |
| 59 | termination of RNA polymerase I transcription (GO:0006363) | 3.03257768 |
| 60 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.94416590 |
| 61 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.94152008 |
| 62 | amino acid salvage (GO:0043102) | 2.91056936 |
| 63 | L-methionine salvage (GO:0071267) | 2.91056936 |
| 64 | L-methionine biosynthetic process (GO:0071265) | 2.91056936 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.88683786 |
| 66 | respiratory electron transport chain (GO:0022904) | 2.86251295 |
| 67 | electron transport chain (GO:0022900) | 2.86009621 |
| 68 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.85355413 |
| 69 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.85355413 |
| 70 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.85355413 |
| 71 | viral mRNA export from host cell nucleus (GO:0046784) | 2.85250370 |
| 72 | replication fork processing (GO:0031297) | 2.84410229 |
| 73 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 2.81952272 |
| 74 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.80783606 |
| 75 | protein prenylation (GO:0018342) | 2.80302086 |
| 76 | prenylation (GO:0097354) | 2.80302086 |
| 77 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.80045459 |
| 78 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.80045459 |
| 79 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.72154770 |
| 80 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.72154770 |
| 81 | NADH dehydrogenase complex assembly (GO:0010257) | 2.72154770 |
| 82 | cytidine metabolic process (GO:0046087) | 2.70405118 |
| 83 | cytidine catabolic process (GO:0006216) | 2.70405118 |
| 84 | cytidine deamination (GO:0009972) | 2.70405118 |
| 85 | GTP biosynthetic process (GO:0006183) | 2.70113763 |
| 86 | rRNA catabolic process (GO:0016075) | 2.69817794 |
| 87 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.67473925 |
| 88 | transcription from RNA polymerase I promoter (GO:0006360) | 2.65603226 |
| 89 | inner mitochondrial membrane organization (GO:0007007) | 2.65562136 |
| 90 | signal peptide processing (GO:0006465) | 2.64349702 |
| 91 | aldehyde catabolic process (GO:0046185) | 2.63642117 |
| 92 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.63317081 |
| 93 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.63317081 |
| 94 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.61772075 |
| 95 | GPI anchor metabolic process (GO:0006505) | 2.61591271 |
| 96 | reciprocal meiotic recombination (GO:0007131) | 2.58953744 |
| 97 | reciprocal DNA recombination (GO:0035825) | 2.58953744 |
| 98 | formation of translation preinitiation complex (GO:0001731) | 2.58702725 |
| 99 | isotype switching (GO:0045190) | 2.57843852 |
| 100 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.57843852 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.14600246 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.12437002 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.83839376 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.65419124 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.64005454 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.16001375 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.03932550 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.63776781 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.59022330 |
| 10 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.56916891 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.50502689 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.45635582 |
| 13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.32427729 |
| 14 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.23060729 |
| 15 | EWS_26573619_Chip-Seq_HEK293_Human | 2.22823050 |
| 16 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.21920855 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.17536766 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.15885475 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.08047764 |
| 20 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.01325722 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.95915148 |
| 22 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.95890019 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.88531986 |
| 24 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.85467542 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84683583 |
| 26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.82289498 |
| 27 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.73611955 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.69756734 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.65077584 |
| 30 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.61925499 |
| 31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.57807078 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.57335701 |
| 33 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.56108514 |
| 34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.55985494 |
| 35 | P300_19829295_ChIP-Seq_ESCs_Human | 1.52460690 |
| 36 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.51598254 |
| 37 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.47264085 |
| 38 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.47264085 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.46154019 |
| 40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.43212428 |
| 41 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39342374 |
| 42 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.39161196 |
| 43 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.37484638 |
| 44 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.37126918 |
| 45 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.37126918 |
| 46 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.36227269 |
| 47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.35852470 |
| 48 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.34270991 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.33517387 |
| 50 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.32850759 |
| 51 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.28009576 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27197683 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.25885333 |
| 54 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.24962848 |
| 55 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.23270853 |
| 56 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.19751062 |
| 57 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.17510137 |
| 58 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.17185774 |
| 59 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.16914266 |
| 60 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.16716930 |
| 61 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.16573897 |
| 62 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16347297 |
| 63 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.16092892 |
| 64 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.15156842 |
| 65 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.14109672 |
| 66 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.14003348 |
| 67 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.13872690 |
| 68 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.12752463 |
| 69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11568112 |
| 70 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.11396836 |
| 71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10945087 |
| 72 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.08641330 |
| 73 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.05356301 |
| 74 | GATA3_26560356_Chip-Seq_TH2_Human | 1.04460772 |
| 75 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.04062862 |
| 76 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.02961573 |
| 77 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02419420 |
| 78 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.01822643 |
| 79 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.00920401 |
| 80 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.00220311 |
| 81 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.99693660 |
| 82 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.99414266 |
| 83 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.98255326 |
| 84 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.98149208 |
| 85 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.96753387 |
| 86 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.96075398 |
| 87 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.95679739 |
| 88 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.95466230 |
| 89 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95308328 |
| 90 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.95028045 |
| 91 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.94547600 |
| 92 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.94001075 |
| 93 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.93991935 |
| 94 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.92915220 |
| 95 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.92837862 |
| 96 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.92059440 |
| 97 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.91765270 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91470509 |
| 99 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.91096328 |
| 100 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90162963 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 3.37415301 |
| 2 | MP0002102_abnormal_ear_morphology | 3.27540834 |
| 3 | MP0003195_calcinosis | 3.13506277 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 3.10780773 |
| 5 | MP0000569_abnormal_digit_pigmentation | 2.97139831 |
| 6 | MP0003183_abnormal_peptide_metabolism | 2.91589337 |
| 7 | MP0002163_abnormal_gland_morphology | 2.90087910 |
| 8 | MP0008058_abnormal_DNA_repair | 2.87484382 |
| 9 | MP0009379_abnormal_foot_pigmentation | 2.63374414 |
| 10 | MP0005645_abnormal_hypothalamus_physiol | 2.53275234 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.39624743 |
| 12 | MP0004381_abnormal_hair_follicle | 2.27985155 |
| 13 | MP0005075_abnormal_melanosome_morpholog | 2.20491191 |
| 14 | MP0004885_abnormal_endolymph | 2.17174973 |
| 15 | MP0002234_abnormal_pharynx_morphology | 2.11371878 |
| 16 | MP0003011_delayed_dark_adaptation | 2.09576729 |
| 17 | MP0003950_abnormal_plasma_membrane | 1.93216924 |
| 18 | MP0001835_abnormal_antigen_presentation | 1.93126182 |
| 19 | MP0003186_abnormal_redox_activity | 1.90697865 |
| 20 | MP0009785_altered_susceptibility_to | 1.88143338 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.88017220 |
| 22 | MP0005671_abnormal_response_to | 1.87952265 |
| 23 | MP0002938_white_spotting | 1.85534584 |
| 24 | MP0005408_hypopigmentation | 1.79325306 |
| 25 | MP0008872_abnormal_physiological_respon | 1.77045965 |
| 26 | MP0003718_maternal_effect | 1.72418641 |
| 27 | MP0005174_abnormal_tail_pigmentation | 1.71185506 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.66776810 |
| 29 | MP0006036_abnormal_mitochondrial_physio | 1.63458945 |
| 30 | MP0010094_abnormal_chromosome_stability | 1.61717518 |
| 31 | MP0006035_abnormal_mitochondrial_morpho | 1.57896421 |
| 32 | MP0002166_altered_tumor_susceptibility | 1.56368524 |
| 33 | MP0000685_abnormal_immune_system | 1.55287346 |
| 34 | MP0000372_irregular_coat_pigmentation | 1.54457420 |
| 35 | MP0005670_abnormal_white_adipose | 1.52846338 |
| 36 | MP0009697_abnormal_copulation | 1.43261720 |
| 37 | MP0008007_abnormal_cellular_replicative | 1.41866208 |
| 38 | MP0000427_abnormal_hair_cycle | 1.40965850 |
| 39 | MP0005379_endocrine/exocrine_gland_phen | 1.39624605 |
| 40 | MP0002148_abnormal_hypersensitivity_rea | 1.37738037 |
| 41 | MP0002160_abnormal_reproductive_system | 1.36245000 |
| 42 | MP0003786_premature_aging | 1.34492858 |
| 43 | MP0009764_decreased_sensitivity_to | 1.32127829 |
| 44 | MP0004084_abnormal_cardiac_muscle | 1.30800404 |
| 45 | MP0002095_abnormal_skin_pigmentation | 1.30078669 |
| 46 | MP0005389_reproductive_system_phenotype | 1.29209408 |
| 47 | MP0005171_absent_coat_pigmentation | 1.28497011 |
| 48 | MP0002006_tumorigenesis | 1.28163440 |
| 49 | MP0005551_abnormal_eye_electrophysiolog | 1.26327792 |
| 50 | MP0004145_abnormal_muscle_electrophysio | 1.24798604 |
| 51 | MP0005387_immune_system_phenotype | 1.22900969 |
| 52 | MP0001790_abnormal_immune_system | 1.22900969 |
| 53 | MP0001800_abnormal_humoral_immune | 1.22356981 |
| 54 | MP0003567_abnormal_fetal_cardiomyocyte | 1.19004618 |
| 55 | MP0005084_abnormal_gallbladder_morpholo | 1.16177565 |
| 56 | MP0006072_abnormal_retinal_apoptosis | 1.15587555 |
| 57 | MP0004742_abnormal_vestibular_system | 1.15086563 |
| 58 | MP0002396_abnormal_hematopoietic_system | 1.05007187 |
| 59 | MP0002138_abnormal_hepatobiliary_system | 1.04774423 |
| 60 | MP0004957_abnormal_blastocyst_morpholog | 1.04531435 |
| 61 | MP0001293_anophthalmia | 0.99201811 |
| 62 | MP0004215_abnormal_myocardial_fiber | 0.98879585 |
| 63 | MP0001501_abnormal_sleep_pattern | 0.98323519 |
| 64 | MP0009250_abnormal_appendicular_skeleto | 0.97630579 |
| 65 | MP0008775_abnormal_heart_ventricle | 0.95676672 |
| 66 | MP0000749_muscle_degeneration | 0.94510832 |
| 67 | MP0006292_abnormal_olfactory_placode | 0.90943551 |
| 68 | MP0008877_abnormal_DNA_methylation | 0.88787208 |
| 69 | MP0002876_abnormal_thyroid_physiology | 0.85783138 |
| 70 | MP0005360_urolithiasis | 0.85577287 |
| 71 | MP0001119_abnormal_female_reproductive | 0.85199991 |
| 72 | MP0000371_diluted_coat_color | 0.84868216 |
| 73 | MP0002452_abnormal_antigen_presenting | 0.84247833 |
| 74 | MP0003880_abnormal_central_pattern | 0.83563010 |
| 75 | MP0005332_abnormal_amino_acid | 0.83392303 |
| 76 | MP0002751_abnormal_autonomic_nervous | 0.83297987 |
| 77 | MP0001919_abnormal_reproductive_system | 0.81318425 |
| 78 | MP0000015_abnormal_ear_pigmentation | 0.80422999 |
| 79 | MP0002723_abnormal_immune_serum | 0.79695977 |
| 80 | MP0005410_abnormal_fertilization | 0.79231934 |
| 81 | MP0002282_abnormal_trachea_morphology | 0.79101899 |
| 82 | MP0005167_abnormal_blood-brain_barrier | 0.78732425 |
| 83 | MP0002420_abnormal_adaptive_immunity | 0.78670398 |
| 84 | MP0002127_abnormal_cardiovascular_syste | 0.78295545 |
| 85 | MP0001819_abnormal_immune_cell | 0.76689298 |
| 86 | MP0009333_abnormal_splenocyte_physiolog | 0.75779958 |
| 87 | MP0001764_abnormal_homeostasis | 0.73990428 |
| 88 | MP0001873_stomach_inflammation | 0.73763003 |
| 89 | MP0010386_abnormal_urinary_bladder | 0.71769281 |
| 90 | MP0005000_abnormal_immune_tolerance | 0.71268347 |
| 91 | MP0000465_gastrointestinal_hemorrhage | 0.67320046 |
| 92 | MP0004043_abnormal_pH_regulation | 0.66963952 |
| 93 | MP0005085_abnormal_gallbladder_physiolo | 0.64099092 |
| 94 | MP0001929_abnormal_gametogenesis | 0.64095193 |
| 95 | MP0003763_abnormal_thymus_physiology | 0.63574551 |
| 96 | MP0001986_abnormal_taste_sensitivity | 0.61920215 |
| 97 | MP0001502_abnormal_circadian_rhythm | 0.61667764 |
| 98 | MP0000716_abnormal_immune_system | 0.61255296 |
| 99 | MP0002398_abnormal_bone_marrow | 0.60173080 |
| 100 | MP0008873_increased_physiological_sensi | 0.58545621 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.14584132 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 3.96185370 |
| 3 | Acute encephalopathy (HP:0006846) | 3.77941784 |
| 4 | Constricted visual fields (HP:0001133) | 3.69697297 |
| 5 | Increased CSF lactate (HP:0002490) | 3.67196685 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.55515919 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.48785252 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 3.40009071 |
| 9 | Optic neuritis (HP:0100653) | 3.40009071 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.34030268 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.30499646 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.22372528 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.15954439 |
| 14 | Hepatic necrosis (HP:0002605) | 3.12904984 |
| 15 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.09899367 |
| 16 | Absent/shortened dynein arms (HP:0200106) | 2.95543130 |
| 17 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.95543130 |
| 18 | Cerebral hypomyelination (HP:0006808) | 2.94289015 |
| 19 | Increased serum lactate (HP:0002151) | 2.87311279 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 2.83365540 |
| 21 | Orchitis (HP:0100796) | 2.82748569 |
| 22 | Abnormality of the renal cortex (HP:0011035) | 2.79053079 |
| 23 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.75199161 |
| 24 | Optic disc pallor (HP:0000543) | 2.70023460 |
| 25 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.68352845 |
| 26 | Congenital sensorineural hearing impairment (HP:0008527) | 2.57228619 |
| 27 | Colon cancer (HP:0003003) | 2.56916613 |
| 28 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.56537310 |
| 29 | Increased serum pyruvate (HP:0003542) | 2.54265635 |
| 30 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.53131829 |
| 31 | Cerebral edema (HP:0002181) | 2.51232038 |
| 32 | Pancreatic cysts (HP:0001737) | 2.49003293 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.45045706 |
| 34 | Hypoproteinemia (HP:0003075) | 2.44700479 |
| 35 | Myositis (HP:0100614) | 2.44338451 |
| 36 | Abnormality of the labia minora (HP:0012880) | 2.42113779 |
| 37 | Exertional dyspnea (HP:0002875) | 2.41090688 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.40364879 |
| 39 | Molar tooth sign on MRI (HP:0002419) | 2.40364879 |
| 40 | Pendular nystagmus (HP:0012043) | 2.39647360 |
| 41 | Oligodactyly (hands) (HP:0001180) | 2.38058232 |
| 42 | Hypoplasia of the uterus (HP:0000013) | 2.37329457 |
| 43 | Attenuation of retinal blood vessels (HP:0007843) | 2.36274525 |
| 44 | Progressive inability to walk (HP:0002505) | 2.34264922 |
| 45 | Increased corneal curvature (HP:0100692) | 2.33988948 |
| 46 | Keratoconus (HP:0000563) | 2.33988948 |
| 47 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.32317749 |
| 48 | Renal cortical cysts (HP:0000803) | 2.29112977 |
| 49 | Keratoconjunctivitis sicca (HP:0001097) | 2.27248540 |
| 50 | Chronic bronchitis (HP:0004469) | 2.26685728 |
| 51 | Leukodystrophy (HP:0002415) | 2.26389894 |
| 52 | Hypokalemic alkalosis (HP:0001949) | 2.24773571 |
| 53 | Abnormality of glycolysis (HP:0004366) | 2.23467641 |
| 54 | Adactyly (HP:0009776) | 2.22520111 |
| 55 | CNS demyelination (HP:0007305) | 2.21203100 |
| 56 | Degeneration of anterior horn cells (HP:0002398) | 2.19109541 |
| 57 | Abnormality of the anterior horn cell (HP:0006802) | 2.19109541 |
| 58 | Poor head control (HP:0002421) | 2.18571855 |
| 59 | Keratoconjunctivitis (HP:0001096) | 2.17961908 |
| 60 | Decreased central vision (HP:0007663) | 2.16597012 |
| 61 | X-linked dominant inheritance (HP:0001423) | 2.16257881 |
| 62 | Type 2 muscle fiber atrophy (HP:0003554) | 2.14803462 |
| 63 | Abnormality of the renal collecting system (HP:0004742) | 2.10056176 |
| 64 | Hyperglycinemia (HP:0002154) | 2.09245496 |
| 65 | Respiratory failure (HP:0002878) | 2.08894106 |
| 66 | Abnormality of the renal medulla (HP:0100957) | 2.04637134 |
| 67 | Cerebral hemorrhage (HP:0001342) | 2.03999863 |
| 68 | Abnormality of macular pigmentation (HP:0008002) | 2.03883224 |
| 69 | Exercise intolerance (HP:0003546) | 2.03791081 |
| 70 | Respiratory difficulties (HP:0002880) | 2.02342038 |
| 71 | Metabolic alkalosis (HP:0200114) | 2.01064308 |
| 72 | True hermaphroditism (HP:0010459) | 2.00039418 |
| 73 | Supernumerary spleens (HP:0009799) | 1.99523010 |
| 74 | Keratitis (HP:0000491) | 1.96388523 |
| 75 | IgG deficiency (HP:0004315) | 1.96012069 |
| 76 | Lactic acidosis (HP:0003128) | 1.95697768 |
| 77 | Dyschromatopsia (HP:0007641) | 1.95630487 |
| 78 | Abnormality of renal resorption (HP:0011038) | 1.95203533 |
| 79 | Nephronophthisis (HP:0000090) | 1.95046659 |
| 80 | CNS hypomyelination (HP:0003429) | 1.93798600 |
| 81 | Inability to walk (HP:0002540) | 1.92454363 |
| 82 | Duplicated collecting system (HP:0000081) | 1.91750034 |
| 83 | Lethargy (HP:0001254) | 1.91535602 |
| 84 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.90930771 |
| 85 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.90930771 |
| 86 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.90858537 |
| 87 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.90737703 |
| 88 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.90245985 |
| 89 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.90245985 |
| 90 | Reticulocytopenia (HP:0001896) | 1.90046029 |
| 91 | Abnormality of DNA repair (HP:0003254) | 1.88681377 |
| 92 | Oral leukoplakia (HP:0002745) | 1.88665841 |
| 93 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88609981 |
| 94 | Pancytopenia (HP:0001876) | 1.88145252 |
| 95 | 3-Methylglutaconic aciduria (HP:0003535) | 1.87213443 |
| 96 | Methylmalonic acidemia (HP:0002912) | 1.86244804 |
| 97 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.85692300 |
| 98 | Hemoptysis (HP:0002105) | 1.85208824 |
| 99 | Aplastic anemia (HP:0001915) | 1.84951367 |
| 100 | Gangrene (HP:0100758) | 1.82840123 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 5.08526687 |
| 2 | TAOK3 | 3.71552997 |
| 3 | VRK2 | 3.36317361 |
| 4 | BUB1 | 2.97233719 |
| 5 | NUAK1 | 2.72646511 |
| 6 | EIF2AK3 | 2.72072051 |
| 7 | TAF1 | 2.40783787 |
| 8 | MST4 | 2.40473184 |
| 9 | MAP3K12 | 2.33098684 |
| 10 | STK39 | 2.20975002 |
| 11 | PINK1 | 2.06437562 |
| 12 | OXSR1 | 2.05208930 |
| 13 | ZAK | 1.98746064 |
| 14 | MKNK2 | 1.94451716 |
| 15 | TSSK6 | 1.94254136 |
| 16 | STK38L | 1.93973006 |
| 17 | NEK1 | 1.84901456 |
| 18 | EIF2AK1 | 1.77367711 |
| 19 | TLK1 | 1.76071609 |
| 20 | MAP2K6 | 1.75917676 |
| 21 | BMPR2 | 1.70831298 |
| 22 | VRK1 | 1.69721112 |
| 23 | PBK | 1.68451167 |
| 24 | WNK3 | 1.58859073 |
| 25 | FLT3 | 1.50278014 |
| 26 | SIK3 | 1.50207295 |
| 27 | PLK3 | 1.48986128 |
| 28 | PLK4 | 1.44759996 |
| 29 | CDK8 | 1.43571169 |
| 30 | WNK4 | 1.37901873 |
| 31 | GRK1 | 1.37134800 |
| 32 | BMPR1B | 1.36696176 |
| 33 | MKNK1 | 1.30985952 |
| 34 | EIF2AK2 | 1.29393198 |
| 35 | STK24 | 1.28369258 |
| 36 | ADRBK2 | 1.21118129 |
| 37 | ACVR1B | 1.14872528 |
| 38 | ERBB3 | 1.12646470 |
| 39 | STK3 | 1.03314502 |
| 40 | PLK2 | 1.00855549 |
| 41 | TESK1 | 0.95052375 |
| 42 | CCNB1 | 0.93559187 |
| 43 | MYLK | 0.91649038 |
| 44 | IKBKB | 0.90072039 |
| 45 | TRIM28 | 0.84373913 |
| 46 | TXK | 0.82766720 |
| 47 | PLK1 | 0.80270008 |
| 48 | MAPK13 | 0.79438491 |
| 49 | TEC | 0.79082152 |
| 50 | BCR | 0.78872005 |
| 51 | FRK | 0.76636549 |
| 52 | TGFBR1 | 0.76565780 |
| 53 | WEE1 | 0.75519506 |
| 54 | GRK5 | 0.75409864 |
| 55 | TNIK | 0.74837884 |
| 56 | MAPKAPK5 | 0.71376910 |
| 57 | DAPK1 | 0.66293031 |
| 58 | CSNK1G3 | 0.65196154 |
| 59 | MAP4K1 | 0.62085522 |
| 60 | SRPK1 | 0.59640322 |
| 61 | TIE1 | 0.58802859 |
| 62 | CSNK1A1L | 0.58251549 |
| 63 | ITK | 0.57225203 |
| 64 | CSNK1G1 | 0.56295591 |
| 65 | CSF1R | 0.55960163 |
| 66 | INSRR | 0.53863813 |
| 67 | PIK3CG | 0.51982056 |
| 68 | DYRK2 | 0.51634625 |
| 69 | KIT | 0.51225138 |
| 70 | FGFR1 | 0.50676679 |
| 71 | CSNK1G2 | 0.47642804 |
| 72 | TGFBR2 | 0.46964758 |
| 73 | NEK2 | 0.45204896 |
| 74 | NME1 | 0.44232341 |
| 75 | TRPM7 | 0.43980047 |
| 76 | DAPK2 | 0.40424545 |
| 77 | ERBB4 | 0.39499965 |
| 78 | IGF1R | 0.37110893 |
| 79 | AURKA | 0.37095258 |
| 80 | LATS1 | 0.35153530 |
| 81 | MAP3K11 | 0.35094410 |
| 82 | STK16 | 0.33925523 |
| 83 | CSNK1A1 | 0.33145762 |
| 84 | MAPKAPK3 | 0.32894291 |
| 85 | CHEK2 | 0.32700065 |
| 86 | PASK | 0.32613669 |
| 87 | PRKCG | 0.31994724 |
| 88 | DAPK3 | 0.31615369 |
| 89 | KDR | 0.31211988 |
| 90 | TTK | 0.30764850 |
| 91 | ATR | 0.30551289 |
| 92 | AURKB | 0.30087770 |
| 93 | CSNK2A2 | 0.29378062 |
| 94 | NLK | 0.28817382 |
| 95 | PRKCE | 0.27930797 |
| 96 | CSNK2A1 | 0.27782057 |
| 97 | PAK3 | 0.27579512 |
| 98 | PRKG1 | 0.27478411 |
| 99 | GSK3A | 0.27451636 |
| 100 | PHKG2 | 0.25411259 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.67416364 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.94452800 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 2.74289856 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.70261479 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.68896395 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.62117079 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.56646520 |
| 8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.34443565 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.31337541 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.29382694 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.29300904 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 2.17295165 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.03471154 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.00916344 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.98555055 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.93888487 |
| 17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.88436323 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.85113289 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.81467248 |
| 20 | RNA transport_Homo sapiens_hsa03013 | 1.68206303 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.66429422 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.58877746 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.54126517 |
| 24 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.52626566 |
| 25 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.52066220 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.48128646 |
| 27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.46559614 |
| 28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.40481569 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.40154814 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.39978536 |
| 31 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.39371199 |
| 32 | DNA replication_Homo sapiens_hsa03030 | 1.38580513 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.37938890 |
| 34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.37280734 |
| 35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.35734875 |
| 36 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.27539234 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.26746962 |
| 38 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.25141659 |
| 39 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.24534794 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.18308978 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.06867314 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.04492745 |
| 43 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.02673392 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.02162206 |
| 45 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.00804020 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 1.00560446 |
| 47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.98019010 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.95166764 |
| 49 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.93202709 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.88310694 |
| 51 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.85510967 |
| 52 | Base excision repair_Homo sapiens_hsa03410 | 0.84620213 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.80524052 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.80370889 |
| 55 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78704602 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.76849478 |
| 57 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.76578592 |
| 58 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.76033747 |
| 59 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.75682965 |
| 60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.75370215 |
| 61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73826865 |
| 62 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.70527161 |
| 63 | Phototransduction_Homo sapiens_hsa04744 | 0.70478346 |
| 64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.65983492 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65131532 |
| 66 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62575281 |
| 67 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.60736108 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58389667 |
| 69 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.58352007 |
| 70 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.58345266 |
| 71 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.56892129 |
| 72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53527259 |
| 73 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53162376 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.51603680 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50720511 |
| 76 | Salivary secretion_Homo sapiens_hsa04970 | 0.50627587 |
| 77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49321405 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.48662711 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.48508437 |
| 80 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.47978098 |
| 81 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46221383 |
| 82 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.46125285 |
| 83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46033612 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43473626 |
| 85 | Nicotine addiction_Homo sapiens_hsa05033 | 0.40915431 |
| 86 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.39417838 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38552501 |
| 88 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38547363 |
| 89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.38353701 |
| 90 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38093283 |
| 91 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.36781085 |
| 92 | Circadian rhythm_Homo sapiens_hsa04710 | 0.36286529 |
| 93 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.35909159 |
| 94 | Carbon metabolism_Homo sapiens_hsa01200 | 0.35579695 |
| 95 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.35186416 |
| 96 | Legionellosis_Homo sapiens_hsa05134 | 0.34340404 |
| 97 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34100139 |
| 98 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.33333480 |
| 99 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32842341 |
| 100 | Peroxisome_Homo sapiens_hsa04146 | 0.31714814 |

