

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 5.45233670 |
| 2 | negative regulation of interleukin-12 production (GO:0032695) | 5.11631118 |
| 3 | activated T cell proliferation (GO:0050798) | 4.96857846 |
| 4 | cell wall macromolecule catabolic process (GO:0016998) | 4.96390769 |
| 5 | negative regulation of T cell mediated immunity (GO:0002710) | 4.79792701 |
| 6 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.67640552 |
| 7 | positive T cell selection (GO:0043368) | 4.64788616 |
| 8 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.30913175 |
| 9 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.30686544 |
| 10 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.29082954 |
| 11 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.15013519 |
| 12 | DNA deamination (GO:0045006) | 4.07178087 |
| 13 | microglial cell activation (GO:0001774) | 4.03706289 |
| 14 | cell wall macromolecule metabolic process (GO:0044036) | 4.02206444 |
| 15 | positive regulation by symbiont of host defense response (GO:0052509) | 3.92652252 |
| 16 | modulation by symbiont of host defense response (GO:0052031) | 3.92652252 |
| 17 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.92652252 |
| 18 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.92652252 |
| 19 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.92652252 |
| 20 | modulation by symbiont of host immune response (GO:0052553) | 3.92652252 |
| 21 | cytidine deamination (GO:0009972) | 3.86264958 |
| 22 | cytidine metabolic process (GO:0046087) | 3.86264958 |
| 23 | cytidine catabolic process (GO:0006216) | 3.86264958 |
| 24 | positive regulation of interleukin-10 production (GO:0032733) | 3.82127091 |
| 25 | platelet dense granule organization (GO:0060155) | 3.82058921 |
| 26 | necroptotic process (GO:0070266) | 3.81062840 |
| 27 | defense response to protozoan (GO:0042832) | 3.77673967 |
| 28 | neutrophil mediated immunity (GO:0002446) | 3.76453600 |
| 29 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.72506810 |
| 30 | melanin biosynthetic process (GO:0042438) | 3.64420061 |
| 31 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.61538625 |
| 32 | secretory granule organization (GO:0033363) | 3.56386074 |
| 33 | hepatocyte apoptotic process (GO:0097284) | 3.51276577 |
| 34 | rRNA methylation (GO:0031167) | 3.50910633 |
| 35 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.47603802 |
| 36 | positive regulation of B cell mediated immunity (GO:0002714) | 3.47603802 |
| 37 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.45068191 |
| 38 | melanin metabolic process (GO:0006582) | 3.44308669 |
| 39 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.43272053 |
| 40 | histone mRNA catabolic process (GO:0071044) | 3.42135659 |
| 41 | developmental pigmentation (GO:0048066) | 3.41160051 |
| 42 | negative thymic T cell selection (GO:0045060) | 3.38613323 |
| 43 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.33566347 |
| 44 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.32464086 |
| 45 | negative regulation of B cell proliferation (GO:0030889) | 3.31997562 |
| 46 | response to pheromone (GO:0019236) | 3.31584359 |
| 47 | protein K63-linked deubiquitination (GO:0070536) | 3.30935532 |
| 48 | programmed necrotic cell death (GO:0097300) | 3.30624440 |
| 49 | fucose catabolic process (GO:0019317) | 3.29422083 |
| 50 | L-fucose metabolic process (GO:0042354) | 3.29422083 |
| 51 | L-fucose catabolic process (GO:0042355) | 3.29422083 |
| 52 | detection of molecule of bacterial origin (GO:0032490) | 3.28668504 |
| 53 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.27057510 |
| 54 | response to protozoan (GO:0001562) | 3.26994890 |
| 55 | T cell selection (GO:0045058) | 3.21996849 |
| 56 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.15155767 |
| 57 | regulation of translational termination (GO:0006449) | 3.14495834 |
| 58 | lactate metabolic process (GO:0006089) | 3.13352221 |
| 59 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.12390416 |
| 60 | necrotic cell death (GO:0070265) | 3.12255625 |
| 61 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.10603943 |
| 62 | myeloid leukocyte mediated immunity (GO:0002444) | 3.10132510 |
| 63 | interferon-gamma production (GO:0032609) | 3.10057576 |
| 64 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.09074931 |
| 65 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.07188070 |
| 66 | regulation of T cell chemotaxis (GO:0010819) | 3.05088540 |
| 67 | positive regulation of T cell chemotaxis (GO:0010820) | 3.05088540 |
| 68 | mature B cell differentiation involved in immune response (GO:0002313) | 3.04951282 |
| 69 | positive regulation of interleukin-1 secretion (GO:0050716) | 3.01563671 |
| 70 | regulation of gamma-delta T cell activation (GO:0046643) | 2.99217651 |
| 71 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.98440262 |
| 72 | rRNA modification (GO:0000154) | 2.95878730 |
| 73 | positive regulation of humoral immune response (GO:0002922) | 2.95659591 |
| 74 | secondary metabolite biosynthetic process (GO:0044550) | 2.95413165 |
| 75 | B cell receptor signaling pathway (GO:0050853) | 2.94578241 |
| 76 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.94029348 |
| 77 | signal peptide processing (GO:0006465) | 2.93234867 |
| 78 | positive regulation of cellular response to oxidative stress (GO:1900409) | 2.92506580 |
| 79 | positive regulation of response to oxidative stress (GO:1902884) | 2.92506580 |
| 80 | cellular extravasation (GO:0045123) | 2.92251014 |
| 81 | negative regulation of adaptive immune response (GO:0002820) | 2.90471444 |
| 82 | melanosome organization (GO:0032438) | 2.90331194 |
| 83 | cellular response to ATP (GO:0071318) | 2.88207730 |
| 84 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.88166708 |
| 85 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.83674862 |
| 86 | mature B cell differentiation (GO:0002335) | 2.83660501 |
| 87 | pigment granule organization (GO:0048753) | 2.82729020 |
| 88 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.82638213 |
| 89 | regulation of regulatory T cell differentiation (GO:0045589) | 2.81362450 |
| 90 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.79893794 |
| 91 | macrophage activation involved in immune response (GO:0002281) | 2.78529497 |
| 92 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.77717432 |
| 93 | macrophage activation (GO:0042116) | 2.76254490 |
| 94 | positive regulation of granulocyte differentiation (GO:0030854) | 2.75959019 |
| 95 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.74835731 |
| 96 | regulation of interleukin-10 production (GO:0032653) | 2.74544876 |
| 97 | maturation of SSU-rRNA (GO:0030490) | 2.73382465 |
| 98 | response to interleukin-15 (GO:0070672) | 2.71966025 |
| 99 | T cell proliferation (GO:0042098) | 2.71088455 |
| 100 | positive thymic T cell selection (GO:0045059) | 2.67421405 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.63685595 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.43733016 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.28525128 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.05155504 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.59754884 |
| 6 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.34234842 |
| 7 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.97872251 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.81579556 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.71888043 |
| 10 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.61517824 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.35034376 |
| 12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.34326566 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.24940801 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.24454397 |
| 15 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.24342027 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.08669253 |
| 17 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.03357154 |
| 18 | GATA3_26560356_Chip-Seq_TH2_Human | 1.95831719 |
| 19 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.94606352 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.94124652 |
| 21 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.84970908 |
| 22 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.81676056 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.73854589 |
| 24 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.73549489 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72883795 |
| 26 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.66358127 |
| 27 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.59380414 |
| 28 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.58335020 |
| 29 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.57336997 |
| 30 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.56551520 |
| 31 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.53773930 |
| 32 | MYB_26560356_Chip-Seq_TH1_Human | 1.53624018 |
| 33 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.49383666 |
| 34 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.48161142 |
| 35 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.48152440 |
| 36 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.45822061 |
| 37 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.44158372 |
| 38 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.40893214 |
| 39 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.39298473 |
| 40 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.38799422 |
| 41 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.37701310 |
| 42 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.36868144 |
| 43 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.35652166 |
| 44 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.35025947 |
| 45 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.34565270 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.34544340 |
| 47 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.33296372 |
| 48 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.30562447 |
| 49 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29840413 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.28790875 |
| 51 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.27056822 |
| 52 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26790332 |
| 53 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.26251041 |
| 54 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.25681255 |
| 55 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.24231331 |
| 56 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.21944258 |
| 57 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.18772914 |
| 58 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18659654 |
| 59 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.16487443 |
| 60 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.14416464 |
| 61 | P300_19829295_ChIP-Seq_ESCs_Human | 1.12434664 |
| 62 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.11745003 |
| 63 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10942029 |
| 64 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.10128677 |
| 65 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.08980687 |
| 66 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08550659 |
| 67 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08126523 |
| 68 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05956608 |
| 69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.05143979 |
| 70 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.04089217 |
| 71 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.03085729 |
| 72 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02230758 |
| 73 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.01623859 |
| 74 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.01282052 |
| 75 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.00655774 |
| 76 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.98746032 |
| 77 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97989725 |
| 78 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.97109983 |
| 79 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.95328155 |
| 80 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.95302314 |
| 81 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.93982054 |
| 82 | TCF4_23295773_ChIP-Seq_U87_Human | 0.93178677 |
| 83 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93077938 |
| 84 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91631712 |
| 85 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.91580750 |
| 86 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.90378957 |
| 87 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.90295936 |
| 88 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.89237414 |
| 89 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.89209465 |
| 90 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.88968129 |
| 91 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88208750 |
| 92 | STAT3_23295773_ChIP-Seq_U87_Human | 0.87669943 |
| 93 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87024658 |
| 94 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86485204 |
| 95 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.86118239 |
| 96 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85282626 |
| 97 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.84751952 |
| 98 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.83514279 |
| 99 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.82569409 |
| 100 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.82474715 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 7.90192702 |
| 2 | MP0000015_abnormal_ear_pigmentation | 5.16226336 |
| 3 | MP0005174_abnormal_tail_pigmentation | 4.81250618 |
| 4 | MP0004381_abnormal_hair_follicle | 3.92884223 |
| 5 | MP0005408_hypopigmentation | 3.50930906 |
| 6 | MP0005075_abnormal_melanosome_morpholog | 3.24064190 |
| 7 | MP0000372_irregular_coat_pigmentation | 3.07940644 |
| 8 | MP0005171_absent_coat_pigmentation | 3.03546214 |
| 9 | MP0002166_altered_tumor_susceptibility | 2.82116151 |
| 10 | MP0002095_abnormal_skin_pigmentation | 2.62743570 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.60579613 |
| 12 | MP0002396_abnormal_hematopoietic_system | 2.46200571 |
| 13 | MP0000371_diluted_coat_color | 2.32721828 |
| 14 | MP0003172_abnormal_lysosome_physiology | 2.14644217 |
| 15 | MP0009785_altered_susceptibility_to | 2.11012480 |
| 16 | MP0005671_abnormal_response_to | 2.10937989 |
| 17 | MP0001800_abnormal_humoral_immune | 2.05589708 |
| 18 | MP0001790_abnormal_immune_system | 2.04341440 |
| 19 | MP0005387_immune_system_phenotype | 2.04341440 |
| 20 | MP0002006_tumorigenesis | 2.02192447 |
| 21 | MP0003763_abnormal_thymus_physiology | 1.97286080 |
| 22 | MP0003724_increased_susceptibility_to | 1.85418894 |
| 23 | MP0008057_abnormal_DNA_replication | 1.74198813 |
| 24 | MP0002723_abnormal_immune_serum | 1.72314396 |
| 25 | MP0003806_abnormal_nucleotide_metabolis | 1.71322121 |
| 26 | MP0003436_decreased_susceptibility_to | 1.70041641 |
| 27 | MP0005025_abnormal_response_to | 1.69749831 |
| 28 | MP0009333_abnormal_splenocyte_physiolog | 1.69476598 |
| 29 | MP0002452_abnormal_antigen_presenting | 1.67921054 |
| 30 | MP0002420_abnormal_adaptive_immunity | 1.67049539 |
| 31 | MP0001819_abnormal_immune_cell | 1.63652795 |
| 32 | MP0003136_yellow_coat_color | 1.63287957 |
| 33 | MP0000685_abnormal_immune_system | 1.62122208 |
| 34 | MP0002419_abnormal_innate_immunity | 1.57080968 |
| 35 | MP0003303_peritoneal_inflammation | 1.56451201 |
| 36 | MP0005000_abnormal_immune_tolerance | 1.47977815 |
| 37 | MP0002148_abnormal_hypersensitivity_rea | 1.46076725 |
| 38 | MP0003656_abnormal_erythrocyte_physiolo | 1.43339872 |
| 39 | MP0002075_abnormal_coat/hair_pigmentati | 1.40919016 |
| 40 | MP0009764_decreased_sensitivity_to | 1.30936684 |
| 41 | MP0003300_gastrointestinal_ulcer | 1.30559725 |
| 42 | MP0006082_CNS_inflammation | 1.29601636 |
| 43 | MP0002398_abnormal_bone_marrow | 1.24769044 |
| 44 | MP0002405_respiratory_system_inflammati | 1.24391124 |
| 45 | MP0001845_abnormal_inflammatory_respons | 1.22419754 |
| 46 | MP0003045_fibrosis | 1.21660164 |
| 47 | MP0005310_abnormal_salivary_gland | 1.18795295 |
| 48 | MP0000689_abnormal_spleen_morphology | 1.18676453 |
| 49 | MP0000716_abnormal_immune_system | 1.18434946 |
| 50 | MP0001851_eye_inflammation | 1.17180604 |
| 51 | MP0001186_pigmentation_phenotype | 1.15207337 |
| 52 | MP0003448_altered_tumor_morphology | 1.09083438 |
| 53 | MP0001324_abnormal_eye_pigmentation | 1.08755432 |
| 54 | MP0005670_abnormal_white_adipose | 1.05968996 |
| 55 | MP0000703_abnormal_thymus_morphology | 1.01249746 |
| 56 | MP0002009_preneoplasia | 0.98812886 |
| 57 | MP0002722_abnormal_immune_system | 0.98317550 |
| 58 | MP0001986_abnormal_taste_sensitivity | 0.91712561 |
| 59 | MP0003195_calcinosis | 0.89692859 |
| 60 | MP0002429_abnormal_blood_cell | 0.89672795 |
| 61 | MP0005377_hearing/vestibular/ear_phenot | 0.89642796 |
| 62 | MP0003878_abnormal_ear_physiology | 0.89642796 |
| 63 | MP0008007_abnormal_cellular_replicative | 0.89066027 |
| 64 | MP0005464_abnormal_platelet_physiology | 0.86548240 |
| 65 | MP0004142_abnormal_muscle_tone | 0.85486175 |
| 66 | MP0003866_abnormal_defecation | 0.82334446 |
| 67 | MP0008260_abnormal_autophagy | 0.78883414 |
| 68 | MP0002877_abnormal_melanocyte_morpholog | 0.77613808 |
| 69 | MP0010155_abnormal_intestine_physiology | 0.75527976 |
| 70 | MP0003186_abnormal_redox_activity | 0.71219659 |
| 71 | MP0005248_abnormal_Harderian_gland | 0.70600164 |
| 72 | MP0003786_premature_aging | 0.69301730 |
| 73 | MP0001501_abnormal_sleep_pattern | 0.68073117 |
| 74 | MP0008469_abnormal_protein_level | 0.67311671 |
| 75 | MP0008873_increased_physiological_sensi | 0.67272027 |
| 76 | MP0002928_abnormal_bile_duct | 0.66211643 |
| 77 | MP0001853_heart_inflammation | 0.65552012 |
| 78 | MP0004808_abnormal_hematopoietic_stem | 0.64983426 |
| 79 | MP0001958_emphysema | 0.63196564 |
| 80 | MP0002638_abnormal_pupillary_reflex | 0.63159838 |
| 81 | MP0002938_white_spotting | 0.62098528 |
| 82 | MP0009763_increased_sensitivity_to | 0.61885753 |
| 83 | MP0005058_abnormal_lysosome_morphology | 0.61862118 |
| 84 | MP0008877_abnormal_DNA_methylation | 0.61515083 |
| 85 | MP0008058_abnormal_DNA_repair | 0.61070786 |
| 86 | MP0003693_abnormal_embryo_hatching | 0.61054435 |
| 87 | MP0004883_abnormal_blood_vessel | 0.61044424 |
| 88 | MP0001533_abnormal_skeleton_physiology | 0.60753058 |
| 89 | MP0000427_abnormal_hair_cycle | 0.59063239 |
| 90 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.54773200 |
| 91 | MP0005266_abnormal_metabolism | 0.53962484 |
| 92 | MP0003252_abnormal_bile_duct | 0.53880932 |
| 93 | MP0002177_abnormal_outer_ear | 0.53449578 |
| 94 | MP0002019_abnormal_tumor_incidence | 0.52513866 |
| 95 | MP0005551_abnormal_eye_electrophysiolog | 0.52244398 |
| 96 | MP0002168_other_aberrant_phenotype | 0.51671858 |
| 97 | MP0001873_stomach_inflammation | 0.47486683 |
| 98 | MP0004134_abnormal_chest_morphology | 0.47300802 |
| 99 | MP0002332_abnormal_exercise_endurance | 0.46594794 |
| 100 | MP0005389_reproductive_system_phenotype | 0.46506906 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 5.08674088 |
| 2 | Large for gestational age (HP:0001520) | 4.33424990 |
| 3 | Aplasia/Hypoplasia of the macula (HP:0008059) | 4.25746475 |
| 4 | Albinism (HP:0001022) | 4.25192208 |
| 5 | Retrobulbar optic neuritis (HP:0100654) | 4.05672260 |
| 6 | Optic neuritis (HP:0100653) | 4.05672260 |
| 7 | Ocular albinism (HP:0001107) | 4.02258935 |
| 8 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 3.95622583 |
| 9 | Hypoproteinemia (HP:0003075) | 3.70832621 |
| 10 | Generalized hypopigmentation (HP:0007513) | 3.63264075 |
| 11 | Abnormality of the pons (HP:0007361) | 3.62680250 |
| 12 | Orchitis (HP:0100796) | 3.51232752 |
| 13 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 3.47817603 |
| 14 | Hypoplasia of the fovea (HP:0007750) | 3.47817603 |
| 15 | Abnormality of T cell number (HP:0011839) | 3.46938186 |
| 16 | T lymphocytopenia (HP:0005403) | 3.40131397 |
| 17 | Iris hypopigmentation (HP:0007730) | 3.38238214 |
| 18 | Cholecystitis (HP:0001082) | 3.35992723 |
| 19 | Abnormal gallbladder physiology (HP:0012438) | 3.35992723 |
| 20 | Recurrent bacterial skin infections (HP:0005406) | 3.34990864 |
| 21 | Myositis (HP:0100614) | 3.30221346 |
| 22 | Pancreatic cysts (HP:0001737) | 3.09399310 |
| 23 | Hypoplasia of the pons (HP:0012110) | 3.04363683 |
| 24 | Recurrent abscess formation (HP:0002722) | 3.02109667 |
| 25 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.95773942 |
| 26 | Progressive inability to walk (HP:0002505) | 2.88113863 |
| 27 | Duplicated collecting system (HP:0000081) | 2.87455601 |
| 28 | Keratoconjunctivitis sicca (HP:0001097) | 2.80653623 |
| 29 | Chronic diarrhea (HP:0002028) | 2.77044799 |
| 30 | Keratoconjunctivitis (HP:0001096) | 2.73151907 |
| 31 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.71249422 |
| 32 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.71187472 |
| 33 | Generalized hypopigmentation of hair (HP:0011358) | 2.64902176 |
| 34 | Patchy hypopigmentation of hair (HP:0011365) | 2.61644012 |
| 35 | Abnormality of the fovea (HP:0000493) | 2.59450497 |
| 36 | Recurrent fungal infections (HP:0002841) | 2.56239642 |
| 37 | Abnormality of the renal collecting system (HP:0004742) | 2.55852159 |
| 38 | Autoimmune hemolytic anemia (HP:0001890) | 2.55296412 |
| 39 | Eosinophilia (HP:0001880) | 2.54353155 |
| 40 | Pulmonary infiltrates (HP:0002113) | 2.50278422 |
| 41 | Reduced antithrombin III activity (HP:0001976) | 2.46223204 |
| 42 | Congenital sensorineural hearing impairment (HP:0008527) | 2.42141331 |
| 43 | Hypochromic microcytic anemia (HP:0004840) | 2.40868944 |
| 44 | Abnormality of glycolysis (HP:0004366) | 2.40515182 |
| 45 | White forelock (HP:0002211) | 2.40473455 |
| 46 | Hemoptysis (HP:0002105) | 2.40315224 |
| 47 | Abnormality of T cells (HP:0002843) | 2.39315330 |
| 48 | Abnormality of eosinophils (HP:0001879) | 2.38683435 |
| 49 | Long foot (HP:0001833) | 2.37009910 |
| 50 | Congenital stationary night blindness (HP:0007642) | 2.36923255 |
| 51 | Blue irides (HP:0000635) | 2.35035891 |
| 52 | Constricted visual fields (HP:0001133) | 2.32494409 |
| 53 | Premature graying of hair (HP:0002216) | 2.31984263 |
| 54 | Type I transferrin isoform profile (HP:0003642) | 2.29923870 |
| 55 | Clubbing of toes (HP:0100760) | 2.29874112 |
| 56 | Arterial thrombosis (HP:0004420) | 2.24117830 |
| 57 | Recurrent skin infections (HP:0001581) | 2.22055736 |
| 58 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.21937686 |
| 59 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.21937686 |
| 60 | Abnormality of the renal cortex (HP:0011035) | 2.19347111 |
| 61 | Facial diplegia (HP:0001349) | 2.19218269 |
| 62 | Thyroiditis (HP:0100646) | 2.19080624 |
| 63 | IgM deficiency (HP:0002850) | 2.17049195 |
| 64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.15150018 |
| 65 | Absent speech (HP:0001344) | 2.14428374 |
| 66 | Encephalitis (HP:0002383) | 2.13811094 |
| 67 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.10282626 |
| 68 | Granulocytopenia (HP:0001913) | 2.06640516 |
| 69 | Leukocytosis (HP:0001974) | 2.05679075 |
| 70 | Cutaneous melanoma (HP:0012056) | 2.04870080 |
| 71 | Abnormality of DNA repair (HP:0003254) | 2.03080383 |
| 72 | Chest pain (HP:0100749) | 2.01564797 |
| 73 | Widely spaced teeth (HP:0000687) | 2.00892653 |
| 74 | Abnormality of the prostate (HP:0008775) | 2.00364841 |
| 75 | Poor head control (HP:0002421) | 2.00131675 |
| 76 | Vasculitis (HP:0002633) | 1.97841211 |
| 77 | Recurrent cutaneous fungal infections (HP:0011370) | 1.97633852 |
| 78 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.97633852 |
| 79 | Gangrene (HP:0100758) | 1.96865923 |
| 80 | Pancreatic fibrosis (HP:0100732) | 1.95237907 |
| 81 | Mediastinal lymphadenopathy (HP:0100721) | 1.93903771 |
| 82 | Prostate neoplasm (HP:0100787) | 1.91711004 |
| 83 | Keratitis (HP:0000491) | 1.91605082 |
| 84 | Abnormal protein glycosylation (HP:0012346) | 1.91154340 |
| 85 | Abnormal glycosylation (HP:0012345) | 1.91154340 |
| 86 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.91154340 |
| 87 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.91154340 |
| 88 | Attenuation of retinal blood vessels (HP:0007843) | 1.90469484 |
| 89 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.88633192 |
| 90 | Abnormality of midbrain morphology (HP:0002418) | 1.86374284 |
| 91 | Molar tooth sign on MRI (HP:0002419) | 1.86374284 |
| 92 | Abnormality of B cell number (HP:0010975) | 1.83755949 |
| 93 | Pulmonary embolism (HP:0002204) | 1.82027314 |
| 94 | Severe visual impairment (HP:0001141) | 1.81809868 |
| 95 | True hermaphroditism (HP:0010459) | 1.79566506 |
| 96 | Exotropia (HP:0000577) | 1.79027186 |
| 97 | Acute hepatic failure (HP:0006554) | 1.78626462 |
| 98 | Recurrent viral infections (HP:0004429) | 1.76695917 |
| 99 | Amyloidosis (HP:0011034) | 1.75464151 |
| 100 | Meningitis (HP:0001287) | 1.75368208 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.10183183 |
| 2 | FRK | 4.09125984 |
| 3 | NUAK1 | 2.81830626 |
| 4 | PDK2 | 2.58880241 |
| 5 | TAOK3 | 2.50839579 |
| 6 | BLK | 2.42944357 |
| 7 | IKBKE | 2.40847447 |
| 8 | NEK9 | 2.13314259 |
| 9 | TSSK6 | 2.04541339 |
| 10 | MAP2K3 | 1.95585569 |
| 11 | MAP2K6 | 1.94423903 |
| 12 | TYK2 | 1.83693710 |
| 13 | STK16 | 1.82489368 |
| 14 | IRAK4 | 1.81968516 |
| 15 | MARK3 | 1.80808156 |
| 16 | IRAK1 | 1.77482797 |
| 17 | TEC | 1.68553851 |
| 18 | MST4 | 1.52316688 |
| 19 | PAK3 | 1.48090527 |
| 20 | PLK2 | 1.47282556 |
| 21 | EIF2AK3 | 1.46684095 |
| 22 | IKBKB | 1.44979500 |
| 23 | SYK | 1.44812736 |
| 24 | MAP3K6 | 1.44237484 |
| 25 | FES | 1.43964823 |
| 26 | WNK1 | 1.42396163 |
| 27 | CSK | 1.40946851 |
| 28 | IRAK2 | 1.38119466 |
| 29 | RIPK4 | 1.37823235 |
| 30 | KIT | 1.35668115 |
| 31 | BMPR2 | 1.34996650 |
| 32 | ACVR1B | 1.30087429 |
| 33 | JAK3 | 1.29983806 |
| 34 | GRK6 | 1.28620587 |
| 35 | WNK4 | 1.28267389 |
| 36 | ZAP70 | 1.25526961 |
| 37 | ITK | 1.20349361 |
| 38 | ERBB3 | 1.19302875 |
| 39 | MAP4K1 | 1.17170518 |
| 40 | PIK3CG | 1.13733168 |
| 41 | PTK2B | 1.11578322 |
| 42 | RAF1 | 1.11530092 |
| 43 | EIF2AK1 | 1.08333149 |
| 44 | ADRBK2 | 1.08145041 |
| 45 | MAP3K3 | 1.06209597 |
| 46 | RPS6KA4 | 1.05818508 |
| 47 | DMPK | 1.04457735 |
| 48 | LYN | 1.02837990 |
| 49 | CAMKK2 | 1.02130952 |
| 50 | PAK6 | 0.96871229 |
| 51 | PIK3CA | 0.95991783 |
| 52 | GRK5 | 0.93885729 |
| 53 | BUB1 | 0.90985831 |
| 54 | STK4 | 0.90620426 |
| 55 | PASK | 0.89345759 |
| 56 | MAP3K14 | 0.88316029 |
| 57 | OXSR1 | 0.86795285 |
| 58 | SRPK1 | 0.83893179 |
| 59 | LCK | 0.83836103 |
| 60 | TLK1 | 0.83332467 |
| 61 | BTK | 0.82845053 |
| 62 | CSNK1A1L | 0.82746729 |
| 63 | HIPK2 | 0.79474825 |
| 64 | MATK | 0.78755756 |
| 65 | RPS6KA5 | 0.77683781 |
| 66 | CDK19 | 0.76318780 |
| 67 | HCK | 0.73688892 |
| 68 | FER | 0.73438302 |
| 69 | CSNK1G3 | 0.70827894 |
| 70 | YES1 | 0.64203794 |
| 71 | MAP3K13 | 0.63416871 |
| 72 | CSNK1G1 | 0.62954481 |
| 73 | STK3 | 0.61514915 |
| 74 | PLK3 | 0.61453682 |
| 75 | STK39 | 0.61220142 |
| 76 | NEK6 | 0.59932266 |
| 77 | TAOK2 | 0.56128029 |
| 78 | ADRBK1 | 0.55835575 |
| 79 | STK10 | 0.54178384 |
| 80 | MAP3K5 | 0.51484927 |
| 81 | PRKCQ | 0.51292419 |
| 82 | CSNK1G2 | 0.50942380 |
| 83 | FGR | 0.50559361 |
| 84 | MAP3K2 | 0.50265705 |
| 85 | PDK1 | 0.49445037 |
| 86 | GRK1 | 0.47488897 |
| 87 | ABL1 | 0.47382533 |
| 88 | JAK1 | 0.46471256 |
| 89 | GSK3A | 0.44616231 |
| 90 | PIM1 | 0.41207273 |
| 91 | TBK1 | 0.40848008 |
| 92 | ERBB2 | 0.39094627 |
| 93 | PRKG1 | 0.37933578 |
| 94 | JAK2 | 0.37717810 |
| 95 | BCKDK | 0.36559906 |
| 96 | PRKCI | 0.36284642 |
| 97 | MAP3K12 | 0.36216184 |
| 98 | BMPR1B | 0.33814190 |
| 99 | CSF1R | 0.33511872 |
| 100 | FGFR2 | 0.32365712 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.91289061 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.68784287 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.59030483 |
| 4 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.41430670 |
| 5 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.89387208 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 2.72822224 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.36146378 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.35465699 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.25495097 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.23470250 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.19189072 |
| 12 | Leishmaniasis_Homo sapiens_hsa05140 | 1.96378758 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.88226341 |
| 14 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.79062006 |
| 15 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.77430020 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.73280373 |
| 17 | Legionellosis_Homo sapiens_hsa05134 | 1.69910349 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.67764106 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.67664310 |
| 20 | Measles_Homo sapiens_hsa05162 | 1.63319979 |
| 21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.62371874 |
| 22 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.61432729 |
| 23 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.55377334 |
| 24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.45891557 |
| 25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.43106052 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.40437141 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.35653866 |
| 28 | Protein export_Homo sapiens_hsa03060 | 1.33066906 |
| 29 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.32758655 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.32145523 |
| 31 | Malaria_Homo sapiens_hsa05144 | 1.26536814 |
| 32 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.25014628 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.24633411 |
| 34 | Tuberculosis_Homo sapiens_hsa05152 | 1.24230928 |
| 35 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.19226152 |
| 36 | Influenza A_Homo sapiens_hsa05164 | 1.13173768 |
| 37 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.10467297 |
| 38 | Basal transcription factors_Homo sapiens_hsa03022 | 1.01760061 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.00540991 |
| 40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.00435380 |
| 41 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.97895819 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 0.97807697 |
| 43 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.97607675 |
| 44 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.92424086 |
| 45 | RNA polymerase_Homo sapiens_hsa03020 | 0.91751343 |
| 46 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.91748247 |
| 47 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.91245082 |
| 48 | RNA degradation_Homo sapiens_hsa03018 | 0.90940015 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.85353264 |
| 50 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.85327922 |
| 51 | Platelet activation_Homo sapiens_hsa04611 | 0.84633835 |
| 52 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.82928436 |
| 53 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.80833294 |
| 54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.78972596 |
| 55 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.78549643 |
| 56 | Apoptosis_Homo sapiens_hsa04210 | 0.75865164 |
| 57 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.74655553 |
| 58 | Viral myocarditis_Homo sapiens_hsa05416 | 0.72311605 |
| 59 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.71324093 |
| 60 | ABC transporters_Homo sapiens_hsa02010 | 0.71279418 |
| 61 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.70498357 |
| 62 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.66006484 |
| 63 | Hepatitis B_Homo sapiens_hsa05161 | 0.65564268 |
| 64 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.65396393 |
| 65 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.65298225 |
| 66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.64087639 |
| 67 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.64031483 |
| 68 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.62122039 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59218905 |
| 70 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.59024085 |
| 71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56469104 |
| 72 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.55055878 |
| 73 | Phagosome_Homo sapiens_hsa04145 | 0.54890593 |
| 74 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.52761748 |
| 75 | Spliceosome_Homo sapiens_hsa03040 | 0.52360956 |
| 76 | Pertussis_Homo sapiens_hsa05133 | 0.51194976 |
| 77 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.49839977 |
| 78 | Parkinsons disease_Homo sapiens_hsa05012 | 0.46521620 |
| 79 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.45633378 |
| 80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44145678 |
| 81 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.42722905 |
| 82 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.41377279 |
| 83 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.39489506 |
| 84 | Phototransduction_Homo sapiens_hsa04744 | 0.38853838 |
| 85 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.38772287 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.38745839 |
| 87 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.38662179 |
| 88 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.34967296 |
| 89 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.33982680 |
| 90 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.33742986 |
| 91 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.32136844 |
| 92 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.31743986 |
| 93 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.29936453 |
| 94 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.29800311 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.29512150 |
| 96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29445317 |
| 97 | Peroxisome_Homo sapiens_hsa04146 | 0.28215836 |
| 98 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.27215329 |
| 99 | Olfactory transduction_Homo sapiens_hsa04740 | 0.26947003 |
| 100 | Base excision repair_Homo sapiens_hsa03410 | 0.25814012 |

