LDLRAD4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)3.66265585
2regulation of germinal center formation (GO:0002634)3.62375422
3mucosal-associated lymphoid tissue development (GO:0048537)3.33433047
4Peyers patch development (GO:0048541)3.33433047
5sodium ion export (GO:0071436)3.30452149
6B cell receptor signaling pathway (GO:0050853)3.29406634
7ionotropic glutamate receptor signaling pathway (GO:0035235)3.22211580
8cellular response to ethanol (GO:0071361)3.21197457
9relaxation of smooth muscle (GO:0044557)3.20490505
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.15226204
11L-amino acid import (GO:0043092)3.13465689
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.04146172
13axon ensheathment in central nervous system (GO:0032291)3.00360714
14central nervous system myelination (GO:0022010)3.00360714
15positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.00257760
16positive T cell selection (GO:0043368)2.98252147
17synaptic vesicle exocytosis (GO:0016079)2.92533345
18negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.81570139
19negative regulation of cell killing (GO:0031342)2.81570139
20positive regulation of granulocyte differentiation (GO:0030854)2.79854307
21antigen processing and presentation of endogenous antigen (GO:0019883)2.78778281
22germinal center formation (GO:0002467)2.77893983
23positive regulation of fibroblast migration (GO:0010763)2.76776922
24cellular potassium ion homeostasis (GO:0030007)2.74012059
25regulation of synaptic vesicle exocytosis (GO:2000300)2.73379131
26membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.73099272
27synaptic vesicle docking involved in exocytosis (GO:0016081)2.71153728
28positive thymic T cell selection (GO:0045059)2.71079608
29signal complex assembly (GO:0007172)2.71032680
30stress fiber assembly (GO:0043149)2.70011438
31regulation of synapse structural plasticity (GO:0051823)2.69733127
32cellular response to interleukin-15 (GO:0071350)2.67958685
33regulation of ARF protein signal transduction (GO:0032012)2.65021320
34response to interleukin-15 (GO:0070672)2.64089670
35positive regulation of gamma-delta T cell activation (GO:0046645)2.63505560
36vocalization behavior (GO:0071625)2.58736801
37regulation of short-term neuronal synaptic plasticity (GO:0048172)2.56066250
38response to muramyl dipeptide (GO:0032495)2.54469522
39cerebellar granule cell differentiation (GO:0021707)2.54369248
40antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.54203478
41negative regulation of cytosolic calcium ion concentration (GO:0051481)2.53516552
42antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.53234537
43locomotory exploration behavior (GO:0035641)2.52752374
44positive regulation of Rap GTPase activity (GO:0032854)2.52629328
45glutamate secretion (GO:0014047)2.51994394
46regulation of Rap GTPase activity (GO:0032317)2.50604925
47positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.49874781
48positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.44965252
49antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.42802937
50positive regulation of chemokine secretion (GO:0090197)2.41583631
51negative regulation of inclusion body assembly (GO:0090084)2.39768320
52regulation of extracellular matrix disassembly (GO:0010715)2.39491779
53regulation of interleukin-4 production (GO:0032673)2.38842790
54regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.38572327
55cerebellar Purkinje cell differentiation (GO:0021702)2.37248591
56collagen fibril organization (GO:0030199)2.35262515
57regulation of gamma-delta T cell differentiation (GO:0045586)2.34198738
58long term synaptic depression (GO:0060292)2.33474106
59negative regulation of lymphocyte mediated immunity (GO:0002707)2.33186445
60regulation of voltage-gated calcium channel activity (GO:1901385)2.30585069
61T cell receptor signaling pathway (GO:0050852)2.30567188
62activation of protein kinase A activity (GO:0034199)2.29965751
63T cell selection (GO:0045058)2.29879043
64negative T cell selection (GO:0043383)2.29145187
65cytoskeletal anchoring at plasma membrane (GO:0007016)2.29073325
66cellular response to epinephrine stimulus (GO:0071872)2.29064520
67tolerance induction (GO:0002507)2.28443066
68negative regulation of B cell mediated immunity (GO:0002713)2.28400543
69negative regulation of immunoglobulin mediated immune response (GO:0002890)2.28400543
70long-term synaptic potentiation (GO:0060291)2.28316710
71cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.28094774
72glutamate receptor signaling pathway (GO:0007215)2.27735607
73regulation of ARF GTPase activity (GO:0032312)2.27721739
74thymic T cell selection (GO:0045061)2.27560520
75astrocyte development (GO:0014002)2.27358717
76keratan sulfate catabolic process (GO:0042340)2.25729617
77negative regulation of myotube differentiation (GO:0010832)2.24691294
78negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.24325380
79negative regulation of neurotransmitter transport (GO:0051589)2.23528112
80regulation of synaptic vesicle transport (GO:1902803)2.23371006
81regulation of B cell receptor signaling pathway (GO:0050855)2.23132129
82nerve growth factor signaling pathway (GO:0038180)2.22830616
83positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.22678308
84positive regulation of macrophage cytokine production (GO:0060907)2.21730959
85negative regulation of neurotransmitter secretion (GO:0046929)2.21404223
86activated T cell proliferation (GO:0050798)2.20182152
87response to laminar fluid shear stress (GO:0034616)2.20161290
88negative regulation of T cell mediated immunity (GO:0002710)2.19960593
89membrane depolarization during action potential (GO:0086010)2.19933820
90regulation of granulocyte differentiation (GO:0030852)2.18558093
91positive regulation of B cell differentiation (GO:0045579)2.18310999
92substrate-dependent cell migration (GO:0006929)2.17796566
93glycine transport (GO:0015816)2.17249750
94amino acid import (GO:0043090)2.17153460
95regulation of macrophage cytokine production (GO:0010935)2.16918086
96neuronal ion channel clustering (GO:0045161)2.16294421
97regulation of gamma-delta T cell activation (GO:0046643)2.15717177
98interferon-gamma-mediated signaling pathway (GO:0060333)2.14762267
99regulation of T cell tolerance induction (GO:0002664)2.14571778
100negative regulation of thymocyte apoptotic process (GO:0070244)2.14350334
101regulation of neuronal synaptic plasticity (GO:0048168)2.13860924
102peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.13685066
103synaptic transmission, glutamatergic (GO:0035249)2.13343189
104monocyte differentiation (GO:0030224)2.13040382
105T-helper cell differentiation (GO:0042093)2.12490415
106CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.12490415
107response to fluid shear stress (GO:0034405)2.12437108
108extracellular fibril organization (GO:0043206)2.12283266
109potassium ion import (GO:0010107)2.12011922
110antigen receptor-mediated signaling pathway (GO:0050851)2.11853215
111protein targeting to plasma membrane (GO:0072661)2.11132644
112phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.10558429
113regulation of dendritic spine morphogenesis (GO:0061001)2.10130160
114cAMP catabolic process (GO:0006198)2.09727191
115regulation of glutamate receptor signaling pathway (GO:1900449)2.09352632
116negative regulation of erythrocyte differentiation (GO:0045647)2.08956454
117mast cell activation (GO:0045576)2.08678369
118neurotransmitter secretion (GO:0007269)2.08293460
119gamma-aminobutyric acid signaling pathway (GO:0007214)2.07950822
120regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.07690411
121negative regulation of leukocyte mediated immunity (GO:0002704)2.07587973
122Rap protein signal transduction (GO:0032486)2.06287930
123regulation of T-helper 2 cell differentiation (GO:0045628)2.06136214
124B cell homeostasis (GO:0001782)2.05948971
125protein localization to endosome (GO:0036010)2.05740774
126cellular sodium ion homeostasis (GO:0006883)2.04634758
127negative regulation of bone resorption (GO:0045779)2.04215006
128negative thymic T cell selection (GO:0045060)2.03988530
129response to host (GO:0075136)2.03819661
130response to host defenses (GO:0052200)2.03819661
131response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.03819661
132positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.03694860
133positive regulation of synapse maturation (GO:0090129)2.03264238
134fibril organization (GO:0097435)2.03128478
135T cell migration (GO:0072678)2.02563028
136cellular response to nerve growth factor stimulus (GO:1990090)2.01907514
137response to nerve growth factor (GO:1990089)2.01907514
138cortical actin cytoskeleton organization (GO:0030866)1.99755467
139extracellular matrix assembly (GO:0085029)1.99640743
140cell adhesion mediated by integrin (GO:0033627)1.98584490
141G-protein coupled glutamate receptor signaling pathway (GO:0007216)1.97417992
142dendritic spine morphogenesis (GO:0060997)1.97384237
143negative regulation of smooth muscle contraction (GO:0045986)1.97370350
144skin morphogenesis (GO:0043589)1.97206092
145clathrin coat assembly (GO:0048268)1.96925623
146apoptotic cell clearance (GO:0043277)1.96734902
147angiogenesis involved in wound healing (GO:0060055)1.96691821
148plasma membrane repair (GO:0001778)1.96358914
149neuromuscular process controlling balance (GO:0050885)1.96241977
150T cell costimulation (GO:0031295)1.95557869
151regulation of vesicle fusion (GO:0031338)1.94884480
152adenosine receptor signaling pathway (GO:0001973)1.94731763
153membrane raft organization (GO:0031579)1.93409757
154long-term memory (GO:0007616)1.93149311
155growth hormone receptor signaling pathway (GO:0060396)1.92880924
156cell communication by electrical coupling (GO:0010644)1.92692199
157lymphocyte costimulation (GO:0031294)1.92629384
158dendrite morphogenesis (GO:0048813)1.91175352
159relaxation of cardiac muscle (GO:0055119)1.91091079
160positive regulation of astrocyte differentiation (GO:0048711)1.91040655
161synaptic vesicle endocytosis (GO:0048488)1.90960273
162G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)1.90493100

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.50643617
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.09155976
3IRF8_22096565_ChIP-ChIP_GC-B_Human2.83272860
4BP1_19119308_ChIP-ChIP_Hs578T_Human2.78868788
5TRIM28_21343339_ChIP-Seq_HEK293_Human2.76168157
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.65458305
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.12139840
8AR_21572438_ChIP-Seq_LNCaP_Human2.11966252
9DROSHA_22980978_ChIP-Seq_HELA_Human2.11613395
10RUNX_20019798_ChIP-Seq_JUKART_Human2.04671616
11VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.98017312
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.94226140
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.87324983
14GBX2_23144817_ChIP-Seq_PC3_Human1.85214385
15SCL_19346495_ChIP-Seq_HPC-7_Human1.84373030
16ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.83216805
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.73425906
18SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.72654124
19MTF2_20144788_ChIP-Seq_MESCs_Mouse1.66912261
20KDM2B_26808549_Chip-Seq_SUP-B15_Human1.65953226
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.62377398
22RNF2_18974828_ChIP-Seq_MESCs_Mouse1.60721805
23EZH2_18974828_ChIP-Seq_MESCs_Mouse1.60721805
24RARB_27405468_Chip-Seq_BRAIN_Mouse1.59918867
25SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.57648180
26TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.50121484
27ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49799555
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46354014
29WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43361481
30SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.42056281
31TP53_16413492_ChIP-PET_HCT116_Human1.41081534
32STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40817025
33KDM2B_26808549_Chip-Seq_DND41_Human1.39243416
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.38825449
35JARID2_20064375_ChIP-Seq_MESCs_Mouse1.36787737
36SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.34125232
37JARID2_20075857_ChIP-Seq_MESCs_Mouse1.32891305
38EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31959906
39KDM2B_26808549_Chip-Seq_K562_Human1.31168560
40SUZ12_27294783_Chip-Seq_ESCs_Mouse1.30307986
41STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.30176632
42GATA2_21666600_ChIP-Seq_HMVEC_Human1.28544443
43RNF2_27304074_Chip-Seq_ESCs_Mouse1.26004475
44THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.25000979
45SPI1_23127762_ChIP-Seq_K562_Human1.24294935
46TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22445952
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22017049
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.21674010
49CDX2_19796622_ChIP-Seq_MESCs_Mouse1.20373092
50CJUN_26792858_Chip-Seq_BT549_Human1.19833471
51RARG_19884340_ChIP-ChIP_MEFs_Mouse1.19336952
52KDM2B_26808549_Chip-Seq_JURKAT_Human1.18806343
53SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.18533323
54EZH2_27294783_Chip-Seq_ESCs_Mouse1.18127120
55NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17926407
56EZH2_22144423_ChIP-Seq_EOC_Human1.17399778
57FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.17239415
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14725652
59GATA1_22025678_ChIP-Seq_K562_Human1.14542026
60WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14361985
61NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.13303316
62GATA3_27048872_Chip-Seq_THYMUS_Human1.13238796
63GATA1_19941827_ChIP-Seq_MEL_Mouse1.12527156
64EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12285391
65RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11372071
66EP300_21415370_ChIP-Seq_HL-1_Mouse1.11114713
67NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.10773099
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.10773099
69NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.10770005
70MYB_26560356_Chip-Seq_TH2_Human1.10485856
71VDR_24787735_ChIP-Seq_THP-1_Human1.10253006
72PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10208217
73TCF7_22412390_ChIP-Seq_EML_Mouse1.10153300
74GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.10120488
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09160733
76KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08784861
77PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08722213
78GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08035110
79ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.07002530
80PRDM14_20953172_ChIP-Seq_ESCs_Human1.06228873
81CLOCK_20551151_ChIP-Seq_293T_Human1.06177066
82KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.05697424
83EED_16625203_ChIP-ChIP_MESCs_Mouse1.04716332
84WT1_19549856_ChIP-ChIP_CCG9911_Human1.03080725
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01360714
86POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01360714
87ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01264868
88VDR_24763502_ChIP-Seq_THP-1_Human1.01075842
89IRF8_27001747_Chip-Seq_BMDM_Mouse1.00909966
90FOXO3_23340844_ChIP-Seq_DLD1_Human1.00332179
91AHR_22903824_ChIP-Seq_MCF-7_Human0.99840779
92DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99727455
93YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99138004
94MYB_21317192_ChIP-Seq_ERMYB_Mouse0.98753814
95AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98716881
96PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.98052447
97TBX20_22328084_ChIP-Seq_HEART_Mouse0.97734184
98TBX20_22080862_ChIP-Seq_HEART_Mouse0.97734184
99Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.97570926
100SMAD4_21799915_ChIP-Seq_A2780_Human0.96720734
101EZH2_27304074_Chip-Seq_ESCs_Mouse0.96300127
102RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.96160129
103BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96115813
104BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95849072
105TAF15_26573619_Chip-Seq_HEK293_Human0.95775225
106STAT3_23295773_ChIP-Seq_U87_Human0.94806377
107EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.93991528
108IRF8_21731497_ChIP-ChIP_J774_Mouse0.93521215
109GATA1_19941826_ChIP-Seq_K562_Human0.93425500
110DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92123875
111CTNNB1_20460455_ChIP-Seq_HCT116_Human0.91634292
112ARNT_22903824_ChIP-Seq_MCF-7_Human0.91317124
113SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.91246832
114NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.90445837
115SOX9_24532713_ChIP-Seq_HFSC_Mouse0.90265103
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.89967678
117RXR_22108803_ChIP-Seq_LS180_Human0.89760363
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.89669252
119ZFP57_27257070_Chip-Seq_ESCs_Mouse0.89377707
120AR_19668381_ChIP-Seq_PC3_Human0.89158780
121SMAD3_21741376_ChIP-Seq_EPCs_Human0.89115709
122TCF4_23295773_ChIP-Seq_U87_Human0.89026521
123VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.88409046
124REST_21632747_ChIP-Seq_MESCs_Mouse0.88288526
125E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.87859070
126SOX2_21211035_ChIP-Seq_LN229_Gbm0.87657164
127MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.87553432
128CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.87467248
129GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87322100
130LXR_22292898_ChIP-Seq_THP-1_Human0.87158416
131SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.85812373
132TP53_18474530_ChIP-ChIP_U2OS_Human0.85784572

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.65569086
2MP0004859_abnormal_synaptic_plasticity3.28187412
3MP0005503_abnormal_tendon_morphology2.61756978
4MP0009780_abnormal_chondrocyte_physiolo2.53074554
5MP0003045_fibrosis2.42639930
6MP0004510_myositis2.40597563
7MP0000013_abnormal_adipose_tissue2.37128065
8MP0003300_gastrointestinal_ulcer2.35219889
9MP0005423_abnormal_somatic_nervous2.34360418
10MP0005275_abnormal_skin_tensile2.34245841
11MP0001835_abnormal_antigen_presentation2.31601834
12MP0001800_abnormal_humoral_immune2.06685587
13MP0003279_aneurysm2.04917050
14MP0002735_abnormal_chemical_nociception2.02953067
15MP0009278_abnormal_bone_marrow2.02260273
16MP0003303_peritoneal_inflammation2.02205635
17MP0000569_abnormal_digit_pigmentation1.98641268
18MP0001790_abnormal_immune_system1.95571344
19MP0005387_immune_system_phenotype1.95571344
20MP0003635_abnormal_synaptic_transmissio1.87375266
21MP0003075_altered_response_to1.86074844
22MP0002090_abnormal_vision1.82751808
23MP0006082_CNS_inflammation1.76212884
24MP0002933_joint_inflammation1.67998377
25MP0000920_abnormal_myelination1.64124481
26MP0002064_seizures1.61830654
27MP0000003_abnormal_adipose_tissue1.59506074
28MP0000751_myopathy1.59358502
29MP0001851_eye_inflammation1.55721573
30MP0002998_abnormal_bone_remodeling1.55682862
31MP0008961_abnormal_basal_metabolism1.54776284
32MP0003705_abnormal_hypodermis_morpholog1.53422308
33MP0002009_preneoplasia1.52957905
34MP0002396_abnormal_hematopoietic_system1.52842420
35MP0002420_abnormal_adaptive_immunity1.52407469
36MP0003724_increased_susceptibility_to1.50722915
37MP0010368_abnormal_lymphatic_system1.49850822
38MP0001819_abnormal_immune_cell1.48177631
39MP0002909_abnormal_adrenal_gland1.46041620
40MP0002822_catalepsy1.45353160
41MP0002166_altered_tumor_susceptibility1.44859401
42MP0002452_abnormal_antigen_presenting1.44063219
43MP0002837_dystrophic_cardiac_calcinosis1.41308304
44MP0003183_abnormal_peptide_metabolism1.37770402
45MP0003436_decreased_susceptibility_to1.37369392
46MP0008569_lethality_at_weaning1.37007764
47MP0004885_abnormal_endolymph1.36175706
48MP0009046_muscle_twitch1.33964545
49MP0002876_abnormal_thyroid_physiology1.33655436
50MP0001958_emphysema1.33211928
51MP0003879_abnormal_hair_cell1.32983133
52MP0002398_abnormal_bone_marrow1.32025131
53MP0009745_abnormal_behavioral_response1.30495734
54MP0004381_abnormal_hair_follicle1.28347346
55MP0003633_abnormal_nervous_system1.28294336
56MP0002063_abnormal_learning/memory/cond1.27349106
57MP0000716_abnormal_immune_system1.26305925
58MP0005023_abnormal_wound_healing1.26226412
59MP0005025_abnormal_response_to1.25758083
60MP0004084_abnormal_cardiac_muscle1.25071785
61MP0000465_gastrointestinal_hemorrhage1.24961295
62MP0001533_abnormal_skeleton_physiology1.24939821
63MP0003566_abnormal_cell_adhesion1.23514326
64MP0001177_atelectasis1.20904948
65MP0002067_abnormal_sensory_capabilities1.20373105
66MP0003091_abnormal_cell_migration1.20353601
67MP0005166_decreased_susceptibility_to1.19892726
68MP0003631_nervous_system_phenotype1.19299956
69MP0002006_tumorigenesis1.17901359
70MP0002734_abnormal_mechanical_nocicepti1.17045042
71MP0004742_abnormal_vestibular_system1.16229563
72MP0003866_abnormal_defecation1.15069600
73MP0000703_abnormal_thymus_morphology1.14819689
74MP0009785_altered_susceptibility_to1.13771738
75MP0002148_abnormal_hypersensitivity_rea1.13624672
76MP0003191_abnormal_cellular_cholesterol1.12895838
77MP0002138_abnormal_hepatobiliary_system1.11394941
78MP0003787_abnormal_imprinting1.11075718
79MP0003690_abnormal_glial_cell1.09723572
80MP0008874_decreased_physiological_sensi1.09171739
81MP0001502_abnormal_circadian_rhythm1.08834403
82MP0003880_abnormal_central_pattern1.08610674
83MP0005671_abnormal_response_to1.08187121
84MP0001970_abnormal_pain_threshold1.07652249
85MP0004270_analgesia1.06920509
86MP0002405_respiratory_system_inflammati1.06787133
87MP0002928_abnormal_bile_duct1.06778460
88MP0005645_abnormal_hypothalamus_physiol1.05449913
89MP0003329_amyloid_beta_deposits1.05218789
90MP0004484_altered_response_of1.04752834
91MP0004272_abnormal_basement_membrane1.04713813
92MP0001545_abnormal_hematopoietic_system1.03841858
93MP0005397_hematopoietic_system_phenotyp1.03841858
94MP0001440_abnormal_grooming_behavior1.03687462
95MP0005375_adipose_tissue_phenotype1.03625404
96MP0003632_abnormal_nervous_system1.02744338
97MP0004036_abnormal_muscle_relaxation1.02570249
98MP0002896_abnormal_bone_mineralization1.02530706
99MP0005595_abnormal_vascular_smooth1.02045607
100MP0002877_abnormal_melanocyte_morpholog0.99992822
101MP0003763_abnormal_thymus_physiology0.98902061
102MP0003634_abnormal_glial_cell0.98576416
103MP0004924_abnormal_behavior0.97714464
104MP0005386_behavior/neurological_phenoty0.97714464
105MP0001968_abnormal_touch/_nociception0.97226621
106MP0009384_cardiac_valve_regurgitation0.96992949
107MP0001984_abnormal_olfaction0.96981249
108MP0005464_abnormal_platelet_physiology0.95464025
109MP0005310_abnormal_salivary_gland0.95182095
110MP0002108_abnormal_muscle_morphology0.95157130
111MP0000778_abnormal_nervous_system0.94446307
112MP0003172_abnormal_lysosome_physiology0.93482210
113MP0005000_abnormal_immune_tolerance0.91975646
114MP0002572_abnormal_emotion/affect_behav0.91184591
115MP0001501_abnormal_sleep_pattern0.91112885
116MP0010155_abnormal_intestine_physiology0.91024783
117MP0005623_abnormal_meninges_morphology0.90601223
118MP0004130_abnormal_muscle_cell0.90254130
119MP0002722_abnormal_immune_system0.89989026
120MP0002419_abnormal_innate_immunity0.89720523
121MP0000689_abnormal_spleen_morphology0.89551704
122MP0002060_abnormal_skin_morphology0.88709614
123MP0008004_abnormal_stomach_pH0.88228794
124MP0003448_altered_tumor_morphology0.87279180
125MP0002295_abnormal_pulmonary_circulatio0.86480139
126MP0000249_abnormal_blood_vessel0.86339378
127MP0000604_amyloidosis0.85818271
128MP0000749_muscle_degeneration0.85271630
129MP0001299_abnormal_eye_distance/0.83712996
130MP0008775_abnormal_heart_ventricle0.83712204
131MP0004947_skin_inflammation0.83322407
132MP0003252_abnormal_bile_duct0.82944964
133MP0000767_abnormal_smooth_muscle0.82871151
134MP0005390_skeleton_phenotype0.81524463
135MP0002272_abnormal_nervous_system0.80919901
136MP0004185_abnormal_adipocyte_glucose0.80682247
137MP0004145_abnormal_muscle_electrophysio0.80667664
138MP0004134_abnormal_chest_morphology0.80335618
139MP0001542_abnormal_bone_strength0.80175693
140MP0002429_abnormal_blood_cell0.79191839
141MP0003795_abnormal_bone_structure0.79053453
142MP0002736_abnormal_nociception_after0.78366201
143MP0000685_abnormal_immune_system0.78333726
144MP0000747_muscle_weakness0.78233936
145MP0005058_abnormal_lysosome_morphology0.77847977
146MP0005167_abnormal_blood-brain_barrier0.77697178
147MP0002066_abnormal_motor_capabilities/c0.77644799
148MP0001348_abnormal_lacrimal_gland0.77505443
149MP0002723_abnormal_immune_serum0.76087956
150MP0002168_other_aberrant_phenotype0.75842014
151MP0004858_abnormal_nervous_system0.75133624
152MP0001486_abnormal_startle_reflex0.74539624
153MP0005508_abnormal_skeleton_morphology0.74409505

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.51659294
2Protrusio acetabuli (HP:0003179)4.33968937
3Aortic dissection (HP:0002647)4.21366444
4Cerebral aneurysm (HP:0004944)4.19175784
5B lymphocytopenia (HP:0010976)4.18700854
6Panhypogammaglobulinemia (HP:0003139)4.14948529
7Abnormality of B cell number (HP:0010975)3.97155252
8Hypoplasia of the thymus (HP:0000778)3.96782500
9Severe combined immunodeficiency (HP:0004430)3.84733009
10Agammaglobulinemia (HP:0004432)3.62654009
11Aortic aneurysm (HP:0004942)3.60581770
12Arterial tortuosity (HP:0005116)3.41832498
13Vascular tortuosity (HP:0004948)3.36501234
14Broad metatarsal (HP:0001783)3.32970920
15Shallow orbits (HP:0000586)3.28266931
16Abnormality of binocular vision (HP:0011514)3.24452133
17Diplopia (HP:0000651)3.24452133
18Febrile seizures (HP:0002373)3.18760888
19Striae distensae (HP:0001065)3.05561446
20Increased cerebral lipofuscin (HP:0011813)3.02658518
21Dilatation of the ascending aorta (HP:0005111)3.01832999
22Mitral valve prolapse (HP:0001634)3.01064754
23Meningitis (HP:0001287)2.97177330
24Increased neuronal autofluorescent lipopigment (HP:0002074)2.87461435
25Recurrent fungal infections (HP:0002841)2.85538464
26Combined immunodeficiency (HP:0005387)2.83438523
27Ankle clonus (HP:0011448)2.69654366
28Genu recurvatum (HP:0002816)2.62633848
29Recurrent bronchitis (HP:0002837)2.57524710
30Eosinophilia (HP:0001880)2.55844623
31Hyperventilation (HP:0002883)2.54659617
32Postural instability (HP:0002172)2.54105903
33Recurrent viral infections (HP:0004429)2.53537377
34Bladder diverticulum (HP:0000015)2.51358912
35Eczematoid dermatitis (HP:0000976)2.46349080
36Disproportionate tall stature (HP:0001519)2.40702993
37Spondylolisthesis (HP:0003302)2.40617032
38Atrophic scars (HP:0001075)2.40018982
39Soft skin (HP:0000977)2.39899938
40Genetic anticipation (HP:0003743)2.38410883
41Cervical subluxation (HP:0003308)2.38186364
42Atonic seizures (HP:0010819)2.36051425
43Cellulitis (HP:0100658)2.33162271
44Action tremor (HP:0002345)2.32135367
45Subaortic stenosis (HP:0001682)2.28111226
46Abnormality of the left ventricular outflow tract (HP:0011103)2.28111226
47Scanning speech (HP:0002168)2.27512009
48Granulocytopenia (HP:0001913)2.27493243
49Abnormality of eosinophils (HP:0001879)2.27303857
50Overgrowth (HP:0001548)2.24085065
51Truncal ataxia (HP:0002078)2.21590563
52Mild short stature (HP:0003502)2.19841067
53Focal seizures (HP:0007359)2.19675845
54Mutism (HP:0002300)2.19237557
55Mediastinal lymphadenopathy (HP:0100721)2.18124197
56Aneurysm (HP:0002617)2.15148412
57Achilles tendon contracture (HP:0001771)2.14467406
58Focal motor seizures (HP:0011153)2.14103858
59Peritonitis (HP:0002586)2.13510472
60Spontaneous hematomas (HP:0007420)2.11930122
61Autoimmune thrombocytopenia (HP:0001973)2.10377900
62Blue sclerae (HP:0000592)2.09992664
63Mitral stenosis (HP:0001718)2.09773164
64Slow saccadic eye movements (HP:0000514)2.08493577
65Depression (HP:0000716)2.07154557
66Colitis (HP:0002583)2.06306173
67T lymphocytopenia (HP:0005403)2.05671689
68Visual hallucinations (HP:0002367)2.05633977
69Abnormality of the periventricular white matter (HP:0002518)2.05503591
70Abnormality of T cell number (HP:0011839)2.04692306
71Dysmetria (HP:0001310)2.03649736
72Spastic gait (HP:0002064)2.02159232
73Joint stiffness (HP:0001387)2.01797883
74Bundle branch block (HP:0011710)2.00985891
75Myokymia (HP:0002411)2.00939893
76Ectopia lentis (HP:0001083)2.00374707
77Abnormality of the Achilles tendon (HP:0005109)1.99929182
78Epileptic encephalopathy (HP:0200134)1.99556842
79Neurofibrillary tangles (HP:0002185)1.98153505
80Hypoproteinemia (HP:0003075)1.98014708
81Stomatitis (HP:0010280)1.97834583
82Retrobulbar optic neuritis (HP:0100654)1.97061515
83Optic neuritis (HP:0100653)1.97061515
84Sepsis (HP:0100806)1.96930719
85Pulmonary embolism (HP:0002204)1.96760442
86Dysmetric saccades (HP:0000641)1.96033111
87Absent speech (HP:0001344)1.96014852
88Torticollis (HP:0000473)1.94798431
89Fragile skin (HP:0001030)1.94296689
90Abnormality of the fingertips (HP:0001211)1.94103656
91Osteoarthritis (HP:0002758)1.93287759
92Scapular winging (HP:0003691)1.93224148
93Systemic lupus erythematosus (HP:0002725)1.92941602
94Vasculitis (HP:0002633)1.92473636
95Recurrent sinusitis (HP:0011108)1.92053140
96Leukocytosis (HP:0001974)1.91957114
97Thickened helices (HP:0000391)1.91270638
98Gastrointestinal infarctions (HP:0005244)1.91186910
99Intention tremor (HP:0002080)1.89898044
100IgG deficiency (HP:0004315)1.89813527
101Hyperextensible skin (HP:0000974)1.88554007
102Round ear (HP:0100830)1.87767720
103Broad ribs (HP:0000885)1.86090418
104Osteomyelitis (HP:0002754)1.85794383
105Abnormality of T cells (HP:0002843)1.85738176
106Lower limb amyotrophy (HP:0007210)1.85501114
107Epiphyseal dysplasia (HP:0002656)1.85047565
108Supranuclear gaze palsy (HP:0000605)1.84628980
109Urinary bladder sphincter dysfunction (HP:0002839)1.84605713
110Increased variability in muscle fiber diameter (HP:0003557)1.84507486
111Myositis (HP:0100614)1.84200437
112Autoimmune hemolytic anemia (HP:0001890)1.83784456
113Hypoplasia of the odontoid process (HP:0003311)1.83420811
114Stomach cancer (HP:0012126)1.82523215
115Ovoid vertebral bodies (HP:0003300)1.82331349
116Congenital stationary night blindness (HP:0007642)1.81186720
117Broad-based gait (HP:0002136)1.81079057
118Increased IgE level (HP:0003212)1.80680719
119Clumsiness (HP:0002312)1.80494378
120Chronic sinusitis (HP:0011109)1.79199358
121Hemiplegia (HP:0002301)1.78741330
122Distal lower limb amyotrophy (HP:0008944)1.76725237
123Difficulty running (HP:0009046)1.76219801
124Gastrointestinal stroma tumor (HP:0100723)1.75311573
125Memory impairment (HP:0002354)1.74435286
126Axonal loss (HP:0003447)1.73634063
127Chronic mucocutaneous candidiasis (HP:0002728)1.73406060
128Recurrent cutaneous fungal infections (HP:0011370)1.73406060
129Cerebral inclusion bodies (HP:0100314)1.73359605
130Ankle contracture (HP:0006466)1.73194210
131Distal upper limb amyotrophy (HP:0007149)1.73074710
132Upper limb amyotrophy (HP:0009129)1.73074710
133Pulmonary infiltrates (HP:0002113)1.72697456
134Hyporeflexia of lower limbs (HP:0002600)1.71784140
135Prolonged QT interval (HP:0001657)1.71531224
136Orchitis (HP:0100796)1.71045584
137Lower limb asymmetry (HP:0100559)1.70437839
138Wormian bones (HP:0002645)1.70048074
139Joint laxity (HP:0001388)1.69787096
140Subacute progressive viral hepatitis (HP:0006572)1.68566169
141Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.68090289
142Papilloma (HP:0012740)1.67417115
143Verrucae (HP:0200043)1.67417115
144Limb-girdle muscle atrophy (HP:0003797)1.67327155
145Acute lymphatic leukemia (HP:0006721)1.67324186
146Abnormal delayed hypersensitivity skin test (HP:0002963)1.66790121
147Abnormality of skeletal muscle fiber size (HP:0012084)1.66309501
148Generalized tonic-clonic seizures (HP:0002069)1.66159324
149Dysdiadochokinesis (HP:0002075)1.66066495
150Vertebral compression fractures (HP:0002953)1.65953222
151Dysostosis multiplex (HP:0000943)1.65339063
152Progressive cerebellar ataxia (HP:0002073)1.65112232
153Atrioventricular block (HP:0001678)1.65017828
154Lower limb muscle weakness (HP:0007340)1.64972860
155Recurrent abscess formation (HP:0002722)1.64492149
156Hypokalemic alkalosis (HP:0001949)1.64464172
157Obstructive sleep apnea (HP:0002870)1.63781947
158Onion bulb formation (HP:0003383)1.63548704
159Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.63016803
160Muscle fiber splitting (HP:0003555)1.61939887
161Spinal canal stenosis (HP:0003416)1.61745516
162Severe short stature (HP:0003510)1.61559105
163Type 1 muscle fiber predominance (HP:0003803)1.61447435
164Absence seizures (HP:0002121)1.61079905
165Abnormality of the odontoid process (HP:0003310)1.60640304
166Bowel diverticulosis (HP:0005222)1.59940324
167Rapidly progressive (HP:0003678)1.58173741
168Neuronal loss in central nervous system (HP:0002529)1.58119699
169Elevated erythrocyte sedimentation rate (HP:0003565)1.56805572
170Papilledema (HP:0001085)1.56655581
171Thyroiditis (HP:0100646)1.55741284
172Slender build (HP:0001533)1.55471537
173Complement deficiency (HP:0004431)1.55059181
174Coxa vara (HP:0002812)1.53880655

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR22.63061111
2DAPK22.44005241
3FGFR42.15340336
4RIPK12.07751624
5DMPK2.05534290
6EPHA42.03768623
7MAP3K142.02155952
8TXK1.96805526
9EEF2K1.87539909
10EPHB11.86382581
11TRIB31.81731769
12PAK61.76366015
13TAOK31.71237494
14MAP4K11.70733787
15JAK11.68436120
16MARK11.67909143
17PRPF4B1.65607536
18ITK1.62633773
19FGFR21.61813641
20UHMK11.61102928
21CAMKK11.55115854
22RIPK41.52159935
23FGFR31.51053012
24SGK21.51024881
25TYK21.50099813
26CAMKK21.42350512
27NLK1.40910578
28MAP3K91.40608538
29PRKCH1.39884440
30MAPK151.35570793
31TNIK1.30654627
32EPHA31.30622918
33NTRK11.30109694
34CDK121.28947306
35BLK1.28541064
36BMPR21.23750013
37DDR21.23299539
38MAPKAPK51.21843024
39TTN1.19082297
40TRPM71.19055719
41PDGFRA1.17310356
42FES1.16901470
43MARK21.14710786
44CASK1.14156933
45RET1.14095596
46HCK1.09022305
47IKBKE1.08592092
48CLK11.08410568
49CSF1R1.08201611
50TAOK11.05660086
51MAPK121.05441539
52MAP3K71.03765065
53TYRO31.03329138
54MINK11.02639588
55PTK2B1.02408009
56TBK11.01395381
57NTRK31.00920138
58NTRK20.98556056
59MAPK70.98198806
60SIK20.98181740
61BTK0.97560451
62CAMK1G0.96687327
63ZAP700.95429140
64SIK10.95339148
65MAP3K100.93704795
66MAPK130.91918266
67GRK60.91256503
68PTK60.90915112
69PKN20.89802143
70MAP3K130.89712444
71PRKD10.89587795
72PDK10.88810504
73PDGFRB0.88535141
74PRKD30.88290400
75IRAK10.85629270
76TNK20.84829309
77PAK30.83868969
78MAPK110.83272387
79CDK50.82918639
80DAPK30.81905918
81MAP3K40.81605660
82KSR20.79835454
83MAPK40.79611998
84CAMK40.78891958
85CDK30.77529750
86SGK10.76311537
87CAMK1D0.75286928
88FYN0.74281351
89LYN0.73894606
90HIPK20.73839188
91KIT0.70788471
92CAMK2B0.69662245
93CAMK10.69197062
94PKN10.68276162
95LCK0.68232420
96CSK0.67606902
97NEK60.67381626
98PAK20.67201156
99MAPK100.66282510
100WNK10.66245933
101PINK10.66244013
102STK110.66064439
103SCYL20.65678173
104PDPK10.64673006
105JAK20.63918494
106STK380.63399173
107FRK0.63048936
108MAP2K20.61473348
109MAP3K20.60688502
110PTK20.60550624
111JAK30.59524809
112STK390.56350536
113SYK0.56255889
114BRD40.55538408
115SGK30.54115631
116CDK150.52338537
117CCNB10.51463026
118TEC0.50675322
119MOS0.50444610
120SGK2230.50265111
121SGK4940.50265111
122CDC42BPA0.49411384
123PIK3CG0.49159069
124RPS6KA30.48836289
125CDK180.48497575
126OBSCN0.47821844
127INSR0.47723290
128CDK140.46573499
129ROCK20.46259796
130PRKCQ0.44862359
131CDK11A0.44561999
132BMX0.44343379
133DYRK1A0.44297895
134CAMK2A0.44273920
135PIK3CA0.43822042
136FER0.42776763
137OXSR10.40935485
138YES10.40862681

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.99273492
2Olfactory transduction_Homo sapiens_hsa047401.61884512
3Circadian entrainment_Homo sapiens_hsa047131.57337752
4Renin secretion_Homo sapiens_hsa049241.56944045
5Morphine addiction_Homo sapiens_hsa050321.55048630
6Allograft rejection_Homo sapiens_hsa053301.54762370
7Dilated cardiomyopathy_Homo sapiens_hsa054141.53584213
8Graft-versus-host disease_Homo sapiens_hsa053321.51904197
9Salivary secretion_Homo sapiens_hsa049701.51658999
10Autoimmune thyroid disease_Homo sapiens_hsa053201.47009115
11Synaptic vesicle cycle_Homo sapiens_hsa047211.46885230
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.44277825
13Oxytocin signaling pathway_Homo sapiens_hsa049211.44124084
14Aldosterone synthesis and secretion_Homo sapiens_hsa049251.43910799
15GABAergic synapse_Homo sapiens_hsa047271.41161646
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.40005295
17T cell receptor signaling pathway_Homo sapiens_hsa046601.39479201
18Osteoclast differentiation_Homo sapiens_hsa043801.39329766
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.31017979
20Asthma_Homo sapiens_hsa053101.29454768
21Long-term potentiation_Homo sapiens_hsa047201.28845974
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.28565202
23Insulin secretion_Homo sapiens_hsa049111.23230697
24Amphetamine addiction_Homo sapiens_hsa050311.22689960
25Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.21372893
26Cholinergic synapse_Homo sapiens_hsa047251.20601371
27Gastric acid secretion_Homo sapiens_hsa049711.19253001
28Glutamatergic synapse_Homo sapiens_hsa047241.17924085
29Type I diabetes mellitus_Homo sapiens_hsa049401.17804252
30Primary immunodeficiency_Homo sapiens_hsa053401.15507748
31Nitrogen metabolism_Homo sapiens_hsa009101.15243885
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.14583216
33Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.14022340
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13801356
35Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.13438735
36Nicotine addiction_Homo sapiens_hsa050331.12803471
37ECM-receptor interaction_Homo sapiens_hsa045121.11625837
38cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10421311
39Focal adhesion_Homo sapiens_hsa045101.08941309
40Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.08938142
41cAMP signaling pathway_Homo sapiens_hsa040241.08168078
42Type II diabetes mellitus_Homo sapiens_hsa049301.07999334
43Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.06920938
44Acute myeloid leukemia_Homo sapiens_hsa052211.06623494
45Cocaine addiction_Homo sapiens_hsa050301.06116117
46AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.04972289
47Estrogen signaling pathway_Homo sapiens_hsa049151.03539437
48Glioma_Homo sapiens_hsa052141.02912203
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.02372691
50Dopaminergic synapse_Homo sapiens_hsa047281.01416403
51Platelet activation_Homo sapiens_hsa046110.99459309
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99243752
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.98782381
54GnRH signaling pathway_Homo sapiens_hsa049120.98210475
55Prolactin signaling pathway_Homo sapiens_hsa049170.97555111
56Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.97437740
57Calcium signaling pathway_Homo sapiens_hsa040200.95361352
58Chemokine signaling pathway_Homo sapiens_hsa040620.95055536
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.93907250
60Malaria_Homo sapiens_hsa051440.91673268
61Toll-like receptor signaling pathway_Homo sapiens_hsa046200.90779998
62Gap junction_Homo sapiens_hsa045400.90696111
63Amoebiasis_Homo sapiens_hsa051460.90319636
64Renal cell carcinoma_Homo sapiens_hsa052110.88840561
65ErbB signaling pathway_Homo sapiens_hsa040120.87556869
66Leishmaniasis_Homo sapiens_hsa051400.86123181
67Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.84758896
68Jak-STAT signaling pathway_Homo sapiens_hsa046300.84426079
69Long-term depression_Homo sapiens_hsa047300.83439372
70Chronic myeloid leukemia_Homo sapiens_hsa052200.82975267
71Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.82273691
72Phospholipase D signaling pathway_Homo sapiens_hsa040720.82018584
73MAPK signaling pathway_Homo sapiens_hsa040100.81379326
74Antigen processing and presentation_Homo sapiens_hsa046120.81086256
75Endocytosis_Homo sapiens_hsa041440.80327223
76Pancreatic cancer_Homo sapiens_hsa052120.79958847
77Rap1 signaling pathway_Homo sapiens_hsa040150.79730031
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79683686
79NF-kappa B signaling pathway_Homo sapiens_hsa040640.78240177
80Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77947184
81Leukocyte transendothelial migration_Homo sapiens_hsa046700.77179966
82B cell receptor signaling pathway_Homo sapiens_hsa046620.76754177
83Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76584466
84Proteoglycans in cancer_Homo sapiens_hsa052050.76472160
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.76362216
86Staphylococcus aureus infection_Homo sapiens_hsa051500.75902485
87Lysosome_Homo sapiens_hsa041420.74453909
88Circadian rhythm_Homo sapiens_hsa047100.74375054
89VEGF signaling pathway_Homo sapiens_hsa043700.73948712
90Endometrial cancer_Homo sapiens_hsa052130.73558701
91Viral myocarditis_Homo sapiens_hsa054160.73477549
92mTOR signaling pathway_Homo sapiens_hsa041500.72477284
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.71821750
94Hematopoietic cell lineage_Homo sapiens_hsa046400.70866578
95Pancreatic secretion_Homo sapiens_hsa049720.70771102
96Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70551861
97Non-small cell lung cancer_Homo sapiens_hsa052230.68771141
98Toxoplasmosis_Homo sapiens_hsa051450.68659362
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.67992503
100TNF signaling pathway_Homo sapiens_hsa046680.67670034
101Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.67587179
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.66210962
103Glycosaminoglycan degradation_Homo sapiens_hsa005310.65709366
104Systemic lupus erythematosus_Homo sapiens_hsa053220.65646045
105Influenza A_Homo sapiens_hsa051640.63400930
106Choline metabolism in cancer_Homo sapiens_hsa052310.63196240
107FoxO signaling pathway_Homo sapiens_hsa040680.61645834
108Salmonella infection_Homo sapiens_hsa051320.61644844
109Dorso-ventral axis formation_Homo sapiens_hsa043200.61323173
110Inositol phosphate metabolism_Homo sapiens_hsa005620.61170220
111Protein digestion and absorption_Homo sapiens_hsa049740.60988811
112Colorectal cancer_Homo sapiens_hsa052100.60880765
113Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60693436
114Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.60510833
115Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60150556
116Measles_Homo sapiens_hsa051620.60052008
117Serotonergic synapse_Homo sapiens_hsa047260.59590401
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59003305
119Tuberculosis_Homo sapiens_hsa051520.58934443
120Axon guidance_Homo sapiens_hsa043600.58260311
121Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.58127197
122Ras signaling pathway_Homo sapiens_hsa040140.57920676
123Hepatitis B_Homo sapiens_hsa051610.57425614
124Prion diseases_Homo sapiens_hsa050200.57122766
125Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.56549851
126Rheumatoid arthritis_Homo sapiens_hsa053230.55372698
127NOD-like receptor signaling pathway_Homo sapiens_hsa046210.55266209

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »