LGI2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.35234134
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.23980063
3locomotory exploration behavior (GO:0035641)5.98572194
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.59122858
5vocalization behavior (GO:0071625)5.54327627
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.51127811
7synaptic vesicle exocytosis (GO:0016079)5.38350706
8glutamate secretion (GO:0014047)5.29436384
9regulation of synaptic vesicle exocytosis (GO:2000300)5.16410761
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.12506706
11layer formation in cerebral cortex (GO:0021819)5.00849419
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.89639732
13gamma-aminobutyric acid transport (GO:0015812)4.85937767
14neurotransmitter secretion (GO:0007269)4.85354883
15regulation of glutamate receptor signaling pathway (GO:1900449)4.75947180
16protein localization to synapse (GO:0035418)4.64718651
17glycine transport (GO:0015816)4.55213101
18exploration behavior (GO:0035640)4.54390716
19proline transport (GO:0015824)4.52557672
20neuronal action potential propagation (GO:0019227)4.52505733
21regulation of synaptic vesicle transport (GO:1902803)4.52156204
22regulation of long-term neuronal synaptic plasticity (GO:0048169)4.45089755
23neuron cell-cell adhesion (GO:0007158)4.40084419
24ionotropic glutamate receptor signaling pathway (GO:0035235)4.31974738
25regulation of neuronal synaptic plasticity (GO:0048168)4.24947655
26membrane repolarization during cardiac muscle cell action potential (GO:0086013)4.21787854
27regulation of synapse structural plasticity (GO:0051823)4.20554341
28cell communication involved in cardiac conduction (GO:0086065)4.17848135
29cellular potassium ion homeostasis (GO:0030007)4.11285857
30pyrimidine nucleobase catabolic process (GO:0006208)4.07148628
31neurotransmitter-gated ion channel clustering (GO:0072578)4.02861543
32dendritic spine morphogenesis (GO:0060997)3.96642031
33synaptic transmission, glutamatergic (GO:0035249)3.93192992
34regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.92228896
35sodium ion export (GO:0071436)3.91279549
36positive regulation of synapse maturation (GO:0090129)3.83949591
37neurotransmitter transport (GO:0006836)3.83237148
38membrane repolarization during action potential (GO:0086011)3.82878901
39neuron-neuron synaptic transmission (GO:0007270)3.81765582
40activation of protein kinase A activity (GO:0034199)3.80201534
41glutamate receptor signaling pathway (GO:0007215)3.77136583
42long-term memory (GO:0007616)3.77075422
43membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.73259055
44adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.72769006
45behavioral response to nicotine (GO:0035095)3.71697377
46potassium ion homeostasis (GO:0055075)3.70352075
47positive regulation of membrane potential (GO:0045838)3.64205828
48cell junction maintenance (GO:0034331)3.61733672
49neuromuscular process controlling balance (GO:0050885)3.53262787
50cell-cell junction maintenance (GO:0045217)3.53073720
51cerebellar Purkinje cell differentiation (GO:0021702)3.50425788
52neuron recognition (GO:0008038)3.48972140
53regulation of neurotransmitter levels (GO:0001505)3.48543507
54positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.47634253
55cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.46709554
56regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.44379465
57regulation of excitatory postsynaptic membrane potential (GO:0060079)3.44111149
58response to parathyroid hormone (GO:0071107)3.43758762
59positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.43543560
60neuromuscular process controlling posture (GO:0050884)3.42650623
61postsynaptic membrane organization (GO:0001941)3.42285038
62negative regulation of synaptic transmission, GABAergic (GO:0032229)3.38306927
63transmission of nerve impulse (GO:0019226)3.37926042
64dendrite morphogenesis (GO:0048813)3.37451899
65regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.36209574
66auditory behavior (GO:0031223)3.35172751
67regulation of neurotransmitter secretion (GO:0046928)3.32579598
68response to auditory stimulus (GO:0010996)3.31670522
69cell communication by electrical coupling (GO:0010644)3.30710609
70establishment of mitochondrion localization (GO:0051654)3.30469363
71regulation of synaptic plasticity (GO:0048167)3.30457441
72positive regulation of synaptic transmission, GABAergic (GO:0032230)3.30283010
73membrane repolarization (GO:0086009)3.30185908
74positive regulation of dendritic spine development (GO:0060999)3.29783099
75regulation of postsynaptic membrane potential (GO:0060078)3.28368174
76regulation of dendritic spine morphogenesis (GO:0061001)3.27864580
77establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.27203917
78mitochondrion transport along microtubule (GO:0047497)3.27203917
79cerebral cortex radially oriented cell migration (GO:0021799)3.26203948
80synaptic vesicle endocytosis (GO:0048488)3.25158607
81axonal fasciculation (GO:0007413)3.24445171
82dopamine biosynthetic process (GO:0042416)3.24384857
83positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.23649099
84sarcoplasmic reticulum calcium ion transport (GO:0070296)3.23603142
85mating behavior (GO:0007617)3.22737132
86gamma-aminobutyric acid signaling pathway (GO:0007214)3.17986747
87body morphogenesis (GO:0010171)3.16942236
88prepulse inhibition (GO:0060134)3.16408982
89regulation of synaptic transmission, glutamatergic (GO:0051966)3.14407256
90synapse assembly (GO:0007416)3.13483645
91long-term synaptic potentiation (GO:0060291)3.13413213
92regulation of vesicle fusion (GO:0031338)3.12966974
93vesicle transport along microtubule (GO:0047496)3.12665629
94positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.12618332
95collecting duct development (GO:0072044)3.11749800
96membrane depolarization during action potential (GO:0086010)3.07656785
97regulation of neurotransmitter transport (GO:0051588)3.07543683
98presynaptic membrane assembly (GO:0097105)3.05760424
99cell migration in hindbrain (GO:0021535)3.05167930
100regulation of heart rate by cardiac conduction (GO:0086091)3.04213168
101suckling behavior (GO:0001967)3.03663118
102neuronal ion channel clustering (GO:0045161)3.02881324
103axon extension (GO:0048675)3.02541737
104neuromuscular process (GO:0050905)3.02253268
105nucleobase catabolic process (GO:0046113)3.01989126
106short-term memory (GO:0007614)3.00918631
107membrane hyperpolarization (GO:0060081)3.00278713
108regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.98541181
109response to pheromone (GO:0019236)2.98314957
110organelle transport along microtubule (GO:0072384)2.97813605
111potassium ion import (GO:0010107)2.97320400
112regulation of synapse maturation (GO:0090128)2.96575992
113positive regulation of potassium ion transmembrane transport (GO:1901381)2.96335758
114cellular component maintenance (GO:0043954)2.96293382
115cerebellar granule cell differentiation (GO:0021707)2.95214973
116regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.94975087
117positive regulation of neurotransmitter transport (GO:0051590)2.93959071
118membrane depolarization (GO:0051899)2.93849638
119cardiac conduction (GO:0061337)2.93294118
120positive regulation of sodium ion transmembrane transport (GO:1902307)2.92795026
121cellular sodium ion homeostasis (GO:0006883)2.92475896
122intraspecies interaction between organisms (GO:0051703)2.92390149
123social behavior (GO:0035176)2.92390149
124presynaptic membrane organization (GO:0097090)2.92246107
125learning (GO:0007612)2.91437168
126regulation of synaptic transmission, GABAergic (GO:0032228)2.90158634
127embryonic body morphogenesis (GO:0010172)2.89454379
128synaptic transmission (GO:0007268)2.89080251
129synapse organization (GO:0050808)2.88499659
130regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.88096232
131dopamine receptor signaling pathway (GO:0007212)2.87664216
132startle response (GO:0001964)2.87638245
133innervation (GO:0060384)2.87204755
134axon cargo transport (GO:0008088)2.87017022
135regulation of ARF protein signal transduction (GO:0032012)2.87001455
136cerebellar Purkinje cell layer development (GO:0021680)2.86231946
137positive regulation of neurotransmitter secretion (GO:0001956)2.85386865
138positive regulation of synaptic transmission (GO:0050806)2.85196605
139adult walking behavior (GO:0007628)2.83854536
140relaxation of cardiac muscle (GO:0055119)2.82722101
141kidney morphogenesis (GO:0060993)2.73830854
142multicellular organismal signaling (GO:0035637)2.72911812
143positive regulation of dendritic spine morphogenesis (GO:0061003)2.71318397
144positive regulation of sodium ion transport (GO:0010765)2.65180570
145regulation of respiratory system process (GO:0044065)2.60402436
146negative regulation of cytosolic calcium ion concentration (GO:0051481)2.56841433
147neuron projection extension (GO:1990138)2.56022880

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.56809492
2GBX2_23144817_ChIP-Seq_PC3_Human3.20169321
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.13875012
4* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.06640930
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.05751095
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.79042384
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.79042384
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.67525717
9REST_21632747_ChIP-Seq_MESCs_Mouse2.65479620
10DROSHA_22980978_ChIP-Seq_HELA_Human2.61011103
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.57020128
12* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.56638777
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.55448144
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.53790053
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.50332750
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.48817850
17RARB_27405468_Chip-Seq_BRAIN_Mouse2.46392380
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.29322507
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.27936729
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26463796
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.22740670
22* REST_18959480_ChIP-ChIP_MESCs_Mouse2.16820621
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.16617663
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09571066
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.09128260
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.05619371
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.02999087
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.02943608
29AR_21572438_ChIP-Seq_LNCaP_Human1.98818066
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.91471889
31GATA1_26923725_Chip-Seq_HPCs_Mouse1.80630186
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.60818364
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.58138449
34* SMAD4_21799915_ChIP-Seq_A2780_Human1.53818856
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53068725
36RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52902097
37SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.49750789
38TP53_20018659_ChIP-ChIP_R1E_Mouse1.44448280
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38869835
40RING1B_27294783_Chip-Seq_ESCs_Mouse1.36219739
41SMAD_19615063_ChIP-ChIP_OVARY_Human1.35858616
42TAF15_26573619_Chip-Seq_HEK293_Human1.35066725
43ZNF274_21170338_ChIP-Seq_K562_Hela1.35030039
44SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33734906
45SOX2_21211035_ChIP-Seq_LN229_Gbm1.33335077
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32826691
47DNAJC2_21179169_ChIP-ChIP_NT2_Human1.31556622
48* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.28380068
49WT1_19549856_ChIP-ChIP_CCG9911_Human1.28243860
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27996097
51CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.26757949
52AR_19668381_ChIP-Seq_PC3_Human1.26132299
53KDM2B_26808549_Chip-Seq_K562_Human1.23714976
54* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23351569
55WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.23197903
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22719991
57ZFP281_18757296_ChIP-ChIP_E14_Mouse1.21843721
58WT1_25993318_ChIP-Seq_PODOCYTE_Human1.21568231
59EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.21153575
60CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19275099
61AR_25329375_ChIP-Seq_VCAP_Human1.19215007
62OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.18756016
63TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.18379340
64* STAT3_23295773_ChIP-Seq_U87_Human1.18276812
65EP300_21415370_ChIP-Seq_HL-1_Mouse1.17896115
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.17291799
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.16895513
68ZNF217_24962896_ChIP-Seq_MCF-7_Human1.16891791
69RING1B_27294783_Chip-Seq_NPCs_Mouse1.15979931
70P300_19829295_ChIP-Seq_ESCs_Human1.15097478
71TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.14594170
72CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14084683
73TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11264333
74ZFP57_27257070_Chip-Seq_ESCs_Mouse1.10756096
75CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.09904913
76CBX2_27304074_Chip-Seq_ESCs_Mouse1.09892543
77EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.09587642
78BMI1_23680149_ChIP-Seq_NPCS_Mouse1.08024139
79YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07434928
80PIAS1_25552417_ChIP-Seq_VCAP_Human1.07299832
81* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07229199
82ISL1_27105846_Chip-Seq_CPCs_Mouse1.07062236
83OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06812002
84AHR_22903824_ChIP-Seq_MCF-7_Human1.06291587
85ARNT_22903824_ChIP-Seq_MCF-7_Human1.06059769
86ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.04928430
87P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04463169
88STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.02633368
89IGF1R_20145208_ChIP-Seq_DFB_Human1.02572384
90SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02421411
91NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02045048
92TCF4_23295773_ChIP-Seq_U87_Human1.01699611
93VDR_22108803_ChIP-Seq_LS180_Human1.01024783
94THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.00766739
95CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00447594
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00323809
97AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99702478
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99519474
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99519474
100SMAD3_21741376_ChIP-Seq_ESCs_Human0.98566513
101RNF2_27304074_Chip-Seq_NSC_Mouse0.96323704
102GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95754866
103TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95474435
104BCAT_22108803_ChIP-Seq_LS180_Human0.94525537
105MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93547110
106ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93292353
107* SMAD4_21741376_ChIP-Seq_HESCs_Human0.93271113
108FUS_26573619_Chip-Seq_HEK293_Human0.92357403
109TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91507978
110RUNX2_22187159_ChIP-Seq_PCA_Human0.90651056
111ZFP281_27345836_Chip-Seq_ESCs_Mouse0.89368319
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.88880631
113SMAD3_21741376_ChIP-Seq_HESCs_Human0.88759076
114TP53_16413492_ChIP-PET_HCT116_Human0.88580951
115KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.87787249
116NR3C1_21868756_ChIP-Seq_MCF10A_Human0.87030544
117SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.86830734
118BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.86495080
119TET1_21490601_ChIP-Seq_MESCs_Mouse0.85931689
120RXR_22108803_ChIP-Seq_LS180_Human0.85770396
121PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.85345883
122ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.84582717
123FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.84437600
124GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84046656
125* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83590766
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.82353398
127SMAD4_21741376_ChIP-Seq_EPCs_Human0.81759572
128CTNNB1_20460455_ChIP-Seq_HCT116_Human0.81243790
129* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.80213735
130TP53_18474530_ChIP-ChIP_U2OS_Human0.79778490

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.44762750
2MP0003635_abnormal_synaptic_transmissio4.20681795
3MP0003880_abnormal_central_pattern4.06636335
4MP0004270_analgesia3.69673857
5MP0009046_muscle_twitch3.45024520
6MP0009745_abnormal_behavioral_response3.33794478
7MP0002063_abnormal_learning/memory/cond3.23220558
8MP0002064_seizures3.09482420
9MP0005423_abnormal_somatic_nervous2.99562891
10MP0001968_abnormal_touch/_nociception2.93277428
11MP0002734_abnormal_mechanical_nocicepti2.83544521
12MP0002572_abnormal_emotion/affect_behav2.67246512
13MP0001486_abnormal_startle_reflex2.54225403
14MP0002272_abnormal_nervous_system2.51482097
15MP0002822_catalepsy2.48265395
16MP0002735_abnormal_chemical_nociception2.34055072
17MP0009780_abnormal_chondrocyte_physiolo2.30943829
18MP0002736_abnormal_nociception_after2.25366556
19MP0002733_abnormal_thermal_nociception2.24538011
20MP0003121_genomic_imprinting2.15348997
21MP0001501_abnormal_sleep_pattern2.15098400
22MP0008569_lethality_at_weaning2.07540966
23MP0001970_abnormal_pain_threshold2.05251518
24MP0002909_abnormal_adrenal_gland2.03018967
25MP0001440_abnormal_grooming_behavior2.00031857
26MP0004858_abnormal_nervous_system1.96372347
27MP0002067_abnormal_sensory_capabilities1.94688797
28MP0002184_abnormal_innervation1.93428025
29MP0003329_amyloid_beta_deposits1.90405641
30MP0004811_abnormal_neuron_physiology1.88851629
31MP0000678_abnormal_parathyroid_gland1.81750978
32MP0000778_abnormal_nervous_system1.80592406
33MP0004924_abnormal_behavior1.79093643
34MP0005386_behavior/neurological_phenoty1.79093643
35MP0004510_myositis1.77343712
36MP0002557_abnormal_social/conspecific_i1.76953281
37MP0000516_abnormal_urinary_system1.76419950
38MP0005367_renal/urinary_system_phenotyp1.76419950
39MP0000955_abnormal_spinal_cord1.72108025
40MP0003122_maternal_imprinting1.68788637
41MP0004885_abnormal_endolymph1.60752664
42MP0003787_abnormal_imprinting1.58205636
43MP0003879_abnormal_hair_cell1.53027727
44MP0003283_abnormal_digestive_organ1.51844013
45MP0003938_abnormal_ear_development1.47995856
46MP0001346_abnormal_lacrimal_gland1.44914335
47MP0002938_white_spotting1.43754875
48MP0005248_abnormal_Harderian_gland1.43723501
49MP0002066_abnormal_motor_capabilities/c1.43376005
50MP0005646_abnormal_pituitary_gland1.43102342
51MP0002102_abnormal_ear_morphology1.40523332
52MP0006276_abnormal_autonomic_nervous1.40150356
53MP0002882_abnormal_neuron_morphology1.39110402
54MP0003633_abnormal_nervous_system1.33118253
55MP0000569_abnormal_digit_pigmentation1.30045774
56MP0004133_heterotaxia1.28543123
57MP0000013_abnormal_adipose_tissue1.26566488
58MP0001984_abnormal_olfaction1.25242027
59MP0004142_abnormal_muscle_tone1.24286475
60MP0008004_abnormal_stomach_pH1.15156977
61MP0005645_abnormal_hypothalamus_physiol1.12710940
62MP0003631_nervous_system_phenotype1.12249918
63MP0001502_abnormal_circadian_rhythm1.11858290
64MP0002152_abnormal_brain_morphology1.09916285
65MP0001177_atelectasis1.08425501
66MP0005058_abnormal_lysosome_morphology1.07088594
67MP0009840_abnormal_foam_cell1.02463361
68MP0003195_calcinosis1.00843785
69MP0004145_abnormal_muscle_electrophysio0.97218958
70MP0008961_abnormal_basal_metabolism0.97208728
71MP0000566_synostosis0.97026477
72MP0005623_abnormal_meninges_morphology0.96525983
73MP0000751_myopathy0.95588683
74MP0001529_abnormal_vocalization0.89885878
75MP0010030_abnormal_orbit_morphology0.88843969
76MP0000026_abnormal_inner_ear0.88084646
77MP0003634_abnormal_glial_cell0.87748753
78MP0008877_abnormal_DNA_methylation0.87524239
79MP0001299_abnormal_eye_distance/0.87504549
80MP0002229_neurodegeneration0.86963405
81MP0002069_abnormal_eating/drinking_beha0.86568686
82MP0003632_abnormal_nervous_system0.86395173
83MP0008872_abnormal_physiological_respon0.86031494
84MP0003690_abnormal_glial_cell0.85988027
85MP0010386_abnormal_urinary_bladder0.85953342
86MP0000049_abnormal_middle_ear0.85764782
87MP0001905_abnormal_dopamine_level0.85629472
88MP0003890_abnormal_embryonic-extraembry0.85431001
89MP0001348_abnormal_lacrimal_gland0.85417349
90MP0001188_hyperpigmentation0.83386006
91MP0003123_paternal_imprinting0.81994452
92MP0004233_abnormal_muscle_weight0.80629403
93MP0003119_abnormal_digestive_system0.80045057
94MP0004085_abnormal_heartbeat0.78808750
95MP0000604_amyloidosis0.76135531
96MP0008874_decreased_physiological_sensi0.75668392
97MP0004742_abnormal_vestibular_system0.75460013
98MP0002116_abnormal_craniofacial_bone0.73515415
99MP0003172_abnormal_lysosome_physiology0.72939780
100MP0000920_abnormal_myelination0.72747759
101MP0009250_abnormal_appendicular_skeleto0.72702696
102MP0004484_altered_response_of0.71603871
103MP0003137_abnormal_impulse_conducting0.70173850
104MP0005394_taste/olfaction_phenotype0.69717927
105MP0005499_abnormal_olfactory_system0.69717927
106MP0001485_abnormal_pinna_reflex0.69296744
107MP0001963_abnormal_hearing_physiology0.69069646
108MP0000631_abnormal_neuroendocrine_gland0.68527766
109MP0003075_altered_response_to0.67879013
110MP0005535_abnormal_body_temperature0.66512364
111MP0002090_abnormal_vision0.65870686
112MP0002752_abnormal_somatic_nervous0.65399251
113MP0008789_abnormal_olfactory_epithelium0.64523648
114MP0003942_abnormal_urinary_system0.64496201
115MP0006292_abnormal_olfactory_placode0.63379452
116MP0005187_abnormal_penis_morphology0.63061047
117MP0010234_abnormal_vibrissa_follicle0.62735737
118MP0004215_abnormal_myocardial_fiber0.62632094
119MP0002837_dystrophic_cardiac_calcinosis0.62508646
120MP0004043_abnormal_pH_regulation0.59882497
121MP0001943_abnormal_respiration0.59864001
122MP0002638_abnormal_pupillary_reflex0.59161680
123MP0005551_abnormal_eye_electrophysiolog0.58238349
124MP0005167_abnormal_blood-brain_barrier0.57722561
125MP0003861_abnormal_nervous_system0.57615558
126MP0010769_abnormal_survival0.55542499
127MP0010770_preweaning_lethality0.54869914
128MP0002082_postnatal_lethality0.54869914

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.85269578
2Myokymia (HP:0002411)6.35361881
3Focal seizures (HP:0007359)5.30453571
4Visual hallucinations (HP:0002367)5.12594506
5Epileptic encephalopathy (HP:0200134)4.51538332
6Atonic seizures (HP:0010819)4.42478651
7Febrile seizures (HP:0002373)4.27714590
8Progressive cerebellar ataxia (HP:0002073)4.21396144
9Action tremor (HP:0002345)4.11273859
10Supranuclear gaze palsy (HP:0000605)4.02907254
11Absence seizures (HP:0002121)3.80249221
12Hyperphosphatemia (HP:0002905)3.77156575
13Ankle clonus (HP:0011448)3.69446661
14Generalized tonic-clonic seizures (HP:0002069)3.64115223
15Papilledema (HP:0001085)3.54985157
16Mutism (HP:0002300)3.44368009
17Mixed hearing impairment (HP:0000410)3.43955288
18Poor eye contact (HP:0000817)3.41525785
19Dialeptic seizures (HP:0011146)3.34020879
20Disinhibition (HP:0000734)3.32504169
21Broad-based gait (HP:0002136)3.27335831
22Abnormal social behavior (HP:0012433)3.16330204
23Impaired social interactions (HP:0000735)3.16330204
24Depression (HP:0000716)3.15559393
25Urinary bladder sphincter dysfunction (HP:0002839)3.05781955
26Gaze-evoked nystagmus (HP:0000640)3.00414493
27Dysdiadochokinesis (HP:0002075)2.97829245
28Impaired vibration sensation in the lower limbs (HP:0002166)2.93295581
29Genetic anticipation (HP:0003743)2.92838977
30Abnormal eating behavior (HP:0100738)2.91376038
31Torticollis (HP:0000473)2.88201653
32Truncal ataxia (HP:0002078)2.84892024
33Postural instability (HP:0002172)2.83096399
34Progressive inability to walk (HP:0002505)2.83007421
35Vacuolated lymphocytes (HP:0001922)2.79471710
36Anxiety (HP:0000739)2.78223388
37Abnormality of calcium-phosphate metabolism (HP:0100530)2.74527224
38Abnormality of glycolipid metabolism (HP:0010969)2.72801923
39Abnormality of liposaccharide metabolism (HP:0010968)2.72801923
40Abnormality of glycosphingolipid metabolism (HP:0004343)2.72801923
41Dysmetria (HP:0001310)2.69998102
42Amblyopia (HP:0000646)2.65422731
43Hemiplegia (HP:0002301)2.62460430
44Urinary urgency (HP:0000012)2.62084547
45Focal dystonia (HP:0004373)2.55845331
46Tetany (HP:0001281)2.55266580
47Insidious onset (HP:0003587)2.54755571
48Termporal pattern (HP:0011008)2.54755571
49Hemiparesis (HP:0001269)2.54429595
50Retinal atrophy (HP:0001105)2.54204715
51Abnormality of binocular vision (HP:0011514)2.52601997
52Diplopia (HP:0000651)2.52601997
53Intention tremor (HP:0002080)2.51111983
54Hyperventilation (HP:0002883)2.51049219
55Scanning speech (HP:0002168)2.50799891
56Ventricular fibrillation (HP:0001663)2.50689120
57Limb dystonia (HP:0002451)2.50549108
58Fetal akinesia sequence (HP:0001989)2.50059486
59Spastic gait (HP:0002064)2.49196579
60Impaired smooth pursuit (HP:0007772)2.48041407
61Excessive salivation (HP:0003781)2.47230268
62Drooling (HP:0002307)2.47230268
63Neurofibrillary tangles (HP:0002185)2.46516678
64Pheochromocytoma (HP:0002666)2.42317986
65Abnormality of the lower motor neuron (HP:0002366)2.41880908
66Nuclear cataract (HP:0100018)2.41840851
67Abnormality of the corticospinal tract (HP:0002492)2.41786619
68Cerebral inclusion bodies (HP:0100314)2.38915912
69Megalencephaly (HP:0001355)2.38547807
70Annular pancreas (HP:0001734)2.37526100
71Amyotrophic lateral sclerosis (HP:0007354)2.36969256
72Epileptiform EEG discharges (HP:0011182)2.36431020
73EEG with generalized epileptiform discharges (HP:0011198)2.36139562
74Craniofacial dystonia (HP:0012179)2.34545217
75Stereotypic behavior (HP:0000733)2.34052137
76Septo-optic dysplasia (HP:0100842)2.33014468
77Agitation (HP:0000713)2.32992952
78Hypsarrhythmia (HP:0002521)2.31639339
79Bradykinesia (HP:0002067)2.31400780
80Alacrima (HP:0000522)2.31314515
81Sleep apnea (HP:0010535)2.31132668
82Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.28417743
83Hip dysplasia (HP:0001385)2.28225786
84Insomnia (HP:0100785)2.27256701
85Abnormality of the lacrimal duct (HP:0011481)2.26969618
86Diminished motivation (HP:0000745)2.26497036
87Pointed chin (HP:0000307)2.26184977
88Syncope (HP:0001279)2.23956022
89Multiple enchondromatosis (HP:0005701)2.23371271
90Status epilepticus (HP:0002133)2.18805131
91Dysmetric saccades (HP:0000641)2.18059262
92Macroorchidism (HP:0000053)2.16663170
93Increased cerebral lipofuscin (HP:0011813)2.15985168
94Lower limb muscle weakness (HP:0007340)2.15324554
95Obstructive sleep apnea (HP:0002870)2.14224793
96Abnormality of ocular smooth pursuit (HP:0000617)2.13530286
97Oligodontia (HP:0000677)2.12842626
98Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.12238137
99Inability to walk (HP:0002540)2.08143130
100Inappropriate behavior (HP:0000719)2.08142627
101Failure to thrive in infancy (HP:0001531)2.08053688
102Akinesia (HP:0002304)2.07658394
103Nasolacrimal duct obstruction (HP:0000579)2.07170963
104Preauricular pit (HP:0004467)2.06659220
105Periauricular skin pits (HP:0100277)2.06659220
106Zonular cataract (HP:0010920)2.05161639
107Intellectual disability, moderate (HP:0002342)2.04146911
108Primary atrial arrhythmia (HP:0001692)2.03311692
109Polyphagia (HP:0002591)2.02332567
110Neuroendocrine neoplasm (HP:0100634)2.02077302
111Abnormality of the labia minora (HP:0012880)2.00628722
112Abnormal number of incisors (HP:0011064)1.99859892
113Absent speech (HP:0001344)1.99764877
114Generalized myoclonic seizures (HP:0002123)1.98393554
115Atrial fibrillation (HP:0005110)1.97270849
116Resting tremor (HP:0002322)1.97099709
117Thoracic kyphosis (HP:0002942)1.96392097
118Exotropia (HP:0000577)1.96378526
119Polydipsia (HP:0001959)1.96278861
120Abnormal drinking behavior (HP:0030082)1.96278861
121Clonus (HP:0002169)1.95727952
122Aqueductal stenosis (HP:0002410)1.93731310
123Supraventricular tachycardia (HP:0004755)1.93423701
124Lower limb amyotrophy (HP:0007210)1.92446360
125Abnormality of the vasculature of the conjunctiva (HP:0008054)1.92160561
126Dysostosis multiplex (HP:0000943)1.91992603
127Restlessness (HP:0000711)1.91770243
128Bundle branch block (HP:0011710)1.91100800
129Upper motor neuron abnormality (HP:0002127)1.91072856
130Supraventricular arrhythmia (HP:0005115)1.90448111
131Abnormality of the nasolacrimal system (HP:0000614)1.88869988
132Infantile muscular hypotonia (HP:0008947)1.88856739
133Neoplasm of the peripheral nervous system (HP:0100007)1.87819046
134Impaired vibratory sensation (HP:0002495)1.87441435
135Agnosia (HP:0010524)1.86989715
136Neuronal loss in central nervous system (HP:0002529)1.85139667
137Maternal diabetes (HP:0009800)1.84769473
138Tracheomalacia (HP:0002779)1.84453939
139Partial agenesis of the corpus callosum (HP:0001338)1.84116096
140Esotropia (HP:0000565)1.84047470
141Concave nail (HP:0001598)1.83517139
142Hypoventilation (HP:0002791)1.82422981
143Apathy (HP:0000741)1.81617577
144Flat capital femoral epiphysis (HP:0003370)1.79898009
145Peripheral hypomyelination (HP:0007182)1.79896554
146Ankyloglossia (HP:0010296)1.79006294
147Protruding tongue (HP:0010808)1.78206400
148Blue irides (HP:0000635)1.77981290
149Turricephaly (HP:0000262)1.77805727
150Gait ataxia (HP:0002066)1.77699522
151Acute lymphatic leukemia (HP:0006721)1.77556495
152Lower limb asymmetry (HP:0100559)1.74291228
153Postural tremor (HP:0002174)1.74096253
154Shawl scrotum (HP:0000049)1.72872931
155Growth hormone deficiency (HP:0000824)1.71537288
156Hypercortisolism (HP:0001578)1.70529305
157Decreased lacrimation (HP:0000633)1.70062627
158Abnormality of the antihelix (HP:0009738)1.69845218
159Absent septum pellucidum (HP:0001331)1.67016480
160Abnormal hair whorl (HP:0010721)1.66673975
161Increased neuronal autofluorescent lipopigment (HP:0002074)1.66175226
162Cortical dysplasia (HP:0002539)1.65721872
163Increased circulating renin level (HP:0000848)1.63468563

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.14495216
2MARK14.06727214
3NTRK34.01986222
4MAP3K43.24056310
5EPHA43.15279900
6MINK12.91084279
7WNK32.88571307
8MAP2K72.74206571
9CAMK1D2.74086731
10PAK62.29252842
11NTRK22.27970804
12DAPK22.27791950
13EPHB22.19177061
14NTRK12.16633087
15CAMKK12.14710084
16PRKD32.13238046
17KSR22.05332384
18MAP2K42.03077999
19MAP3K121.89964032
20LATS21.80391170
21STK381.59457565
22KSR11.47296759
23CDK51.46625884
24PHKG21.43345297
25PHKG11.43345297
26MAP3K21.38316094
27DYRK21.36982109
28MAPK131.34251526
29TAOK11.31969781
30CAMKK21.31563521
31PNCK1.27399854
32PLK21.26724532
33CASK1.24647540
34GRK51.21407795
35UHMK11.21226447
36DMPK1.19912953
37SIK21.19217654
38PKN21.17764207
39DAPK11.16729404
40PRKCG1.15875736
41RIPK41.14839669
42TNIK1.10625151
43SCYL21.10524509
44ACVR1B1.08485552
45PRKCH1.08243998
46ALK1.08166156
47GRK71.07915911
48CDK191.07831139
49RET1.07240831
50MAP3K111.06421054
51TYRO31.01311548
52LMTK21.01271070
53WNK11.00695745
54MKNK20.99914888
55STK110.95858496
56PDK20.95656308
57RIPK10.94157720
58SGK4940.88474553
59SGK2230.88474553
60PRPF4B0.84852660
61CDK180.84273917
62CAMK10.83954149
63CDK150.83931961
64FES0.82821201
65CDK140.82533365
66CAMK2A0.78684764
67CSNK1G20.76256660
68PAK30.75796145
69SGK20.75272619
70MARK20.72585401
71CDK11A0.72285891
72SGK30.72031558
73ARAF0.68094981
74SGK10.67279083
75DYRK1A0.67084010
76PINK10.67051154
77CAMK1G0.65892900
78BMPR1B0.65633044
79TGFBR10.65353779
80ADRBK20.65096303
81NEK10.62366587
82BCR0.61050886
83CSNK1E0.59275589
84CDC42BPA0.59057554
85MAP3K10.56340131
86OBSCN0.56229669
87ERBB30.53513443
88MAP3K60.53289834
89PRKCZ0.53267463
90PRKCE0.53097799
91PDK10.52708341
92MAP3K130.51728401
93FGR0.51702017
94BRSK10.51243980
95CAMK2B0.51166227
96MAP2K60.51064926
97PDPK10.50942748
98LIMK10.50174835
99RPS6KA30.49115852
100FYN0.48462195
101RPS6KA20.48413861
102ICK0.47783165
103NEK60.47393995
104CSNK1G30.46240715
105MAPK100.45812806
106FER0.45053706
107RAF10.44088101
108CDC70.43832253
109PDGFRA0.43009887
110PKN10.42153402
111FGFR20.41955960
112DYRK30.40866357
113CAMK2G0.40143770
114MOS0.39872068
115OXSR10.39192288
116DDR20.38913250
117MAP2K10.37644015
118MAPKAPK50.37535346
119CSNK1G10.36694619
120MAP3K50.36242411
121BMPR20.35064709
122TNK20.34264488
123PRKACA0.33713757
124TESK10.33152716
125CAMK2D0.32778054
126CSNK1A10.32164421
127MAPK120.31358838
128CAMK40.30500155
129PRKAA10.29782945
130CCNB10.29307004
131PRKACB0.29243683

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.43935737
2Synaptic vesicle cycle_Homo sapiens_hsa047213.39227491
3GABAergic synapse_Homo sapiens_hsa047272.71171058
4Olfactory transduction_Homo sapiens_hsa047402.54975241
5Circadian entrainment_Homo sapiens_hsa047132.52010036
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.47932044
7Long-term potentiation_Homo sapiens_hsa047202.46472866
8Morphine addiction_Homo sapiens_hsa050322.38935662
9Glutamatergic synapse_Homo sapiens_hsa047242.37170962
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.30604334
11Amphetamine addiction_Homo sapiens_hsa050312.19591105
12Vitamin B6 metabolism_Homo sapiens_hsa007502.11018753
13Dopaminergic synapse_Homo sapiens_hsa047282.09292410
14Salivary secretion_Homo sapiens_hsa049702.02044319
15Insulin secretion_Homo sapiens_hsa049111.99498795
16Lysosome_Homo sapiens_hsa041421.95874124
17Cholinergic synapse_Homo sapiens_hsa047251.88305074
18Gastric acid secretion_Homo sapiens_hsa049711.85892433
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.72154620
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.70015954
21Taste transduction_Homo sapiens_hsa047421.69469468
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.67937738
23Long-term depression_Homo sapiens_hsa047301.67414623
24Cocaine addiction_Homo sapiens_hsa050301.60847316
25Renin secretion_Homo sapiens_hsa049241.55664115
26Oxytocin signaling pathway_Homo sapiens_hsa049211.52555396
27Serotonergic synapse_Homo sapiens_hsa047261.50483494
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41146950
29GnRH signaling pathway_Homo sapiens_hsa049121.40227586
30Other glycan degradation_Homo sapiens_hsa005111.38670961
31Calcium signaling pathway_Homo sapiens_hsa040201.36718300
32Gap junction_Homo sapiens_hsa045401.34416389
33Type II diabetes mellitus_Homo sapiens_hsa049301.32719155
34Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.29915469
35Estrogen signaling pathway_Homo sapiens_hsa049151.27500081
36Collecting duct acid secretion_Homo sapiens_hsa049661.24857878
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23917523
38cAMP signaling pathway_Homo sapiens_hsa040241.22533253
39Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.20962093
40Axon guidance_Homo sapiens_hsa043601.20507714
41Mineral absorption_Homo sapiens_hsa049781.16533794
42Glioma_Homo sapiens_hsa052141.15619882
43ErbB signaling pathway_Homo sapiens_hsa040121.06865623
44Melanogenesis_Homo sapiens_hsa049161.04473672
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03446750
46Pancreatic secretion_Homo sapiens_hsa049720.99967150
47cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97629456
48Dorso-ventral axis formation_Homo sapiens_hsa043200.94631724
49Vibrio cholerae infection_Homo sapiens_hsa051100.93437313
50Oocyte meiosis_Homo sapiens_hsa041140.89863103
51Hedgehog signaling pathway_Homo sapiens_hsa043400.89418413
52Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88192988
53Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87486466
54Basal cell carcinoma_Homo sapiens_hsa052170.85358121
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84697518
56Type I diabetes mellitus_Homo sapiens_hsa049400.83351671
57Nitrogen metabolism_Homo sapiens_hsa009100.83270136
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.83217166
59Selenocompound metabolism_Homo sapiens_hsa004500.83157027
60Thyroid hormone synthesis_Homo sapiens_hsa049180.83069534
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82989719
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.82841424
63Protein digestion and absorption_Homo sapiens_hsa049740.82313652
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.81948830
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.80961951
66Cardiac muscle contraction_Homo sapiens_hsa042600.80427718
67Glycosaminoglycan degradation_Homo sapiens_hsa005310.78054430
68Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78013442
69Tight junction_Homo sapiens_hsa045300.77356661
70Neurotrophin signaling pathway_Homo sapiens_hsa047220.75590512
71Dilated cardiomyopathy_Homo sapiens_hsa054140.74161879
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72953452
73Phagosome_Homo sapiens_hsa041450.71172546
74Sphingolipid metabolism_Homo sapiens_hsa006000.70933203
75MAPK signaling pathway_Homo sapiens_hsa040100.70348849
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.69426801
77Endometrial cancer_Homo sapiens_hsa052130.67572695
78Choline metabolism in cancer_Homo sapiens_hsa052310.67391606
79Rheumatoid arthritis_Homo sapiens_hsa053230.66087147
80mTOR signaling pathway_Homo sapiens_hsa041500.63997823
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63670420
82Amoebiasis_Homo sapiens_hsa051460.62888805
83Hippo signaling pathway_Homo sapiens_hsa043900.62424692
84Rap1 signaling pathway_Homo sapiens_hsa040150.60450585
85Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60038340
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59607247
87Ras signaling pathway_Homo sapiens_hsa040140.58607942
88Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58172006
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57374280
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57009331
91Glucagon signaling pathway_Homo sapiens_hsa049220.56900522
92Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.56853137
93VEGF signaling pathway_Homo sapiens_hsa043700.54803107
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.54383618
95Ether lipid metabolism_Homo sapiens_hsa005650.54340568
96Endocytosis_Homo sapiens_hsa041440.53850406
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53759286
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53270359
99Insulin signaling pathway_Homo sapiens_hsa049100.52753738
100Renal cell carcinoma_Homo sapiens_hsa052110.52735116
101Bile secretion_Homo sapiens_hsa049760.52341368
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52056780
103Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51918619
104Prion diseases_Homo sapiens_hsa050200.48157393
105Alcoholism_Homo sapiens_hsa050340.46993753
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.46282849
107Phototransduction_Homo sapiens_hsa047440.45465741
108Salmonella infection_Homo sapiens_hsa051320.45324640
109Non-small cell lung cancer_Homo sapiens_hsa052230.45088722
110Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44983732
111Wnt signaling pathway_Homo sapiens_hsa043100.44123596
112Ovarian steroidogenesis_Homo sapiens_hsa049130.41182205
113Inositol phosphate metabolism_Homo sapiens_hsa005620.41114836
114SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39759026
115Parkinsons disease_Homo sapiens_hsa050120.39738214
116Chemokine signaling pathway_Homo sapiens_hsa040620.38958823
117Colorectal cancer_Homo sapiens_hsa052100.38768075
118Adherens junction_Homo sapiens_hsa045200.36003126
119Circadian rhythm_Homo sapiens_hsa047100.35712208
120Prolactin signaling pathway_Homo sapiens_hsa049170.35376961
121Oxidative phosphorylation_Homo sapiens_hsa001900.33388162
122Butanoate metabolism_Homo sapiens_hsa006500.33232381
123Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.32681363
124Tuberculosis_Homo sapiens_hsa051520.32303649
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.31414606
126ECM-receptor interaction_Homo sapiens_hsa045120.31154797
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30745921

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