LGI3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)8.73120510
2axon ensheathment in central nervous system (GO:0032291)8.66190162
3central nervous system myelination (GO:0022010)8.66190162
4sodium ion export (GO:0071436)5.94443458
5neurotransmitter secretion (GO:0007269)5.73117614
6ensheathment of neurons (GO:0007272)5.62200863
7axon ensheathment (GO:0008366)5.62200863
8myelination (GO:0042552)5.61384130
9fatty acid elongation (GO:0030497)5.50647828
10positive regulation of synapse maturation (GO:0090129)4.76089377
11regulation of long-term neuronal synaptic plasticity (GO:0048169)4.70770893
12neurotransmitter transport (GO:0006836)4.64425150
13long-chain fatty acid biosynthetic process (GO:0042759)4.52863178
14potassium ion homeostasis (GO:0055075)4.48082286
15regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.47838447
16exploration behavior (GO:0035640)4.47716793
17cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.45942301
18negative regulation of neurotransmitter secretion (GO:0046929)4.35836805
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.34384928
20neuronal action potential propagation (GO:0019227)4.22055738
21regulation of neurotransmitter levels (GO:0001505)4.13719031
22regulation of neurotransmitter secretion (GO:0046928)4.10764196
23regulation of glutamate receptor signaling pathway (GO:1900449)4.10396918
24regulation of synaptic plasticity (GO:0048167)4.07985341
25negative regulation of neurotransmitter transport (GO:0051589)3.97970494
26neuromuscular process controlling balance (GO:0050885)3.96545688
27oligodendrocyte differentiation (GO:0048709)3.93343340
28regulation of ARF protein signal transduction (GO:0032012)3.92311022
29presynaptic membrane organization (GO:0097090)3.92290967
30positive regulation of dendritic spine development (GO:0060999)3.92000812
31regulation of excitatory postsynaptic membrane potential (GO:0060079)3.90854882
32L-amino acid import (GO:0043092)3.88998123
33synaptic vesicle endocytosis (GO:0048488)3.88804450
34neurotransmitter-gated ion channel clustering (GO:0072578)3.86082100
35postsynaptic membrane organization (GO:0001941)3.85969230
36myelin maintenance (GO:0043217)3.83850568
37cerebellar Purkinje cell differentiation (GO:0021702)3.81553667
38cell communication by electrical coupling (GO:0010644)3.80102722
39negative regulation of dendrite morphogenesis (GO:0050774)3.78815663
40neuron cell-cell adhesion (GO:0007158)3.78559951
41cellular sodium ion homeostasis (GO:0006883)3.78443995
42regulation of synapse structural plasticity (GO:0051823)3.76984222
43regulation of synapse maturation (GO:0090128)3.74821138
44synaptic vesicle maturation (GO:0016188)3.74733793
45regulation of neurotransmitter transport (GO:0051588)3.74357558
46positive regulation of neurotransmitter secretion (GO:0001956)3.73546905
47proline transport (GO:0015824)3.72379241
48presynaptic membrane assembly (GO:0097105)3.70216772
49positive regulation of neurotransmitter transport (GO:0051590)3.68098762
50transmission of nerve impulse (GO:0019226)3.68019964
51neurotransmitter uptake (GO:0001504)3.67377590
52regulation of vesicle fusion (GO:0031338)3.67108158
53adult walking behavior (GO:0007628)3.65163134
54peptidyl-tyrosine autophosphorylation (GO:0038083)3.63782726
55apical protein localization (GO:0045176)3.59985689
56positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.59193008
57regulation of postsynaptic membrane potential (GO:0060078)3.58049229
58establishment of mitochondrion localization (GO:0051654)3.55225195
59long-term memory (GO:0007616)3.54719691
60eye photoreceptor cell differentiation (GO:0001754)3.48921611
61photoreceptor cell differentiation (GO:0046530)3.48921611
62locomotory exploration behavior (GO:0035641)3.47789084
63acidic amino acid transport (GO:0015800)3.47251068
64long-term synaptic potentiation (GO:0060291)3.38930420
65neuronal ion channel clustering (GO:0045161)3.38377027
66negative regulation of protein localization to cell surface (GO:2000009)3.38256428
67glycerophospholipid catabolic process (GO:0046475)3.37287633
68regulation of dendritic spine development (GO:0060998)3.36372169
69positive regulation of dendritic spine morphogenesis (GO:0061003)3.34951183
70asymmetric protein localization (GO:0008105)3.34307688
71regulation of short-term neuronal synaptic plasticity (GO:0048172)3.32861181
72adhesion of symbiont to host cell (GO:0044650)3.29874283
73virion attachment to host cell (GO:0019062)3.29874283
74negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.29207738
75positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.28788380
76astrocyte development (GO:0014002)3.26150102
77regulation of synaptic transmission (GO:0050804)3.26108550
78cerebellar granule cell differentiation (GO:0021707)3.25587351
79substantia nigra development (GO:0021762)3.25227099
80vesicle docking involved in exocytosis (GO:0006904)3.24397118
81membrane depolarization during action potential (GO:0086010)3.23457633
82positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.22727108
83membrane depolarization (GO:0051899)3.22369854
84regulation of synaptic vesicle exocytosis (GO:2000300)3.21940967
85synaptic vesicle exocytosis (GO:0016079)3.16866316
86regulation of collateral sprouting (GO:0048670)3.16850651
87creatine metabolic process (GO:0006600)3.14710522
88establishment of synaptic vesicle localization (GO:0097480)3.13288906
89synaptic vesicle transport (GO:0048489)3.13288906
90glycine transport (GO:0015816)3.11405163
91cerebellar Purkinje cell layer development (GO:0021680)3.10855784
92negative regulation of axonogenesis (GO:0050771)3.09177309
93auditory behavior (GO:0031223)3.08486105
94L-glutamate transport (GO:0015813)3.08156298
95dendritic spine organization (GO:0097061)3.08077596
96synaptic transmission (GO:0007268)3.06644898
97cell differentiation in hindbrain (GO:0021533)3.05916218
98G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.05805756
99ionotropic glutamate receptor signaling pathway (GO:0035235)3.05144119
100myelination in peripheral nervous system (GO:0022011)3.00784575
101peripheral nervous system axon ensheathment (GO:0032292)3.00784575
102dicarboxylic acid transport (GO:0006835)2.99888271
103neuromuscular synaptic transmission (GO:0007274)2.99791625
104chemosensory behavior (GO:0007635)2.99615868
105gamma-aminobutyric acid transport (GO:0015812)2.99498962
106glutamate secretion (GO:0014047)2.99440164
107detection of calcium ion (GO:0005513)2.99081818
108amino acid import (GO:0043090)2.98981221
109activation of protein kinase A activity (GO:0034199)2.98448423
110vesicle docking (GO:0048278)2.97710557
111cell communication involved in cardiac conduction (GO:0086065)2.97213878
112long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.96571217
113vocalization behavior (GO:0071625)2.96165830
114nerve growth factor signaling pathway (GO:0038180)2.85440596
115response to methylmercury (GO:0051597)2.85291402
116neuron recognition (GO:0008038)2.84708505
117cellular response to epinephrine stimulus (GO:0071872)2.82652535
118neuromuscular process controlling posture (GO:0050884)2.82279904
119mating behavior (GO:0007617)2.80702194
120membrane tubulation (GO:0097320)2.80545480
121gamma-aminobutyric acid signaling pathway (GO:0007214)2.80078212
122dendritic spine morphogenesis (GO:0060997)2.79713583
123protein palmitoylation (GO:0018345)2.73847240
124import into cell (GO:0098657)2.73642445
125cellular potassium ion homeostasis (GO:0030007)2.72941601
126protein localization to endosome (GO:0036010)2.72624705
127synaptic transmission, glutamatergic (GO:0035249)2.70806373
128negative regulation of axon extension (GO:0030517)2.70352663
129long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.68392913
130negative regulation of synaptic transmission, GABAergic (GO:0032229)2.68368353
131positive regulation of action potential (GO:0045760)2.68311360
132neuron-neuron synaptic transmission (GO:0007270)2.68044961
133regulation of voltage-gated calcium channel activity (GO:1901385)2.67721138
134glutamate receptor signaling pathway (GO:0007215)2.67150666
135protein localization to synapse (GO:0035418)2.66565024
136potassium ion import (GO:0010107)2.66050071
137regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.65811378
138regulation of neuronal synaptic plasticity (GO:0048168)2.65355510
139cholesterol biosynthetic process (GO:0006695)2.63431983
140dendrite morphogenesis (GO:0048813)2.63421877
141regulation of dendritic spine morphogenesis (GO:0061001)2.63275975
142regulation of synaptic vesicle transport (GO:1902803)2.63058890
143cerebral cortex radially oriented cell migration (GO:0021799)2.62938846
144membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.58227729
145cellular response to catecholamine stimulus (GO:0071870)2.58102266
146cellular response to monoamine stimulus (GO:0071868)2.58102266
147positive regulation of membrane potential (GO:0045838)2.57616058
148neuron remodeling (GO:0016322)2.56529630
149response to redox state (GO:0051775)2.56131355
150adult locomotory behavior (GO:0008344)2.53814696
151axonal fasciculation (GO:0007413)2.53520103
152axon development (GO:0061564)2.52250747
153membrane assembly (GO:0071709)2.51412185
154negative regulation of inclusion body assembly (GO:0090084)2.51309165
155fatty-acyl-CoA biosynthetic process (GO:0046949)2.50463587
156layer formation in cerebral cortex (GO:0021819)2.49440202
157positive regulation of oligodendrocyte differentiation (GO:0048714)2.49296228
158response to epinephrine (GO:0071871)2.48271029
159glycosylceramide metabolic process (GO:0006677)2.48241386
160cytoskeletal anchoring at plasma membrane (GO:0007016)2.47385925
161positive regulation of potassium ion transport (GO:0043268)2.47281633

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.48726734
2GBX2_23144817_ChIP-Seq_PC3_Human3.21116573
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.90895045
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.84264591
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.73410152
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.72746726
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.56204906
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.56204906
9* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.47885916
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.44635484
11* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38343451
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.30828480
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.27832813
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.25279820
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.24556112
16DROSHA_22980978_ChIP-Seq_HELA_Human2.21865489
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18946263
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.15638262
19* EZH2_27294783_Chip-Seq_ESCs_Mouse2.14296929
20SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.04540003
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.01490963
22RARB_27405468_Chip-Seq_BRAIN_Mouse1.97504420
23TAF15_26573619_Chip-Seq_HEK293_Human1.93412222
24RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.92564348
25REST_21632747_ChIP-Seq_MESCs_Mouse1.83890954
26ZFP281_18757296_ChIP-ChIP_E14_Mouse1.80557022
27AR_21572438_ChIP-Seq_LNCaP_Human1.74331691
28VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73141576
29OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64086645
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.63380413
31REST_18959480_ChIP-ChIP_MESCs_Mouse1.56339874
32CDX2_19796622_ChIP-Seq_MESCs_Mouse1.52820472
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51690410
34* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.48513208
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44261189
36RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41942723
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.39821184
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.39084014
39* TET1_21490601_ChIP-Seq_MESCs_Mouse1.38235696
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.38220193
41ZFP281_27345836_Chip-Seq_ESCs_Mouse1.37938237
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37578594
43IKZF1_21737484_ChIP-ChIP_HCT116_Human1.34759555
44* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.34479901
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.34315774
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.31029913
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.30007058
48CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.28916591
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28461087
50CTCF_27219007_Chip-Seq_Bcells_Human1.27077956
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.26614488
52ER_23166858_ChIP-Seq_MCF-7_Human1.24746680
53LXR_22292898_ChIP-Seq_THP-1_Human1.24098148
54MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23962869
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.23956256
56TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20960539
57WT1_25993318_ChIP-Seq_PODOCYTE_Human1.20680441
58KDM2B_26808549_Chip-Seq_SUP-B15_Human1.20350003
59SMAD4_21799915_ChIP-Seq_A2780_Human1.19432495
60CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.19033621
61PIAS1_25552417_ChIP-Seq_VCAP_Human1.18798796
62STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17127688
63P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16832221
64SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.16082300
65SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14703085
66BMI1_23680149_ChIP-Seq_NPCS_Mouse1.14702566
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.14399455
68AHR_22903824_ChIP-Seq_MCF-7_Human1.13352629
69NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.12857907
70OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.12674421
71P300_19829295_ChIP-Seq_ESCs_Human1.12246613
72* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.11969402
73STAT3_23295773_ChIP-Seq_U87_Human1.11119450
74CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.08479326
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08431392
76ARNT_22903824_ChIP-Seq_MCF-7_Human1.06863532
77ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06296926
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05153904
79NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04305542
80GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04274873
81OCT4_19829295_ChIP-Seq_ESCs_Human1.04136725
82GATA1_26923725_Chip-Seq_HPCs_Mouse1.03580536
83SOX2_21211035_ChIP-Seq_LN229_Gbm1.01821788
84EP300_21415370_ChIP-Seq_HL-1_Mouse1.01449066
85RING1B_27294783_Chip-Seq_NPCs_Mouse1.01223539
86ESR1_20079471_ChIP-ChIP_T-47D_Human1.01221606
87POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00258370
88TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00201814
89VDR_22108803_ChIP-Seq_LS180_Human0.99875849
90TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98781784
91CTNNB1_20460455_ChIP-Seq_HCT116_Human0.98305834
92SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98147916
93TCF4_23295773_ChIP-Seq_U87_Human0.97863226
94SMC4_20622854_ChIP-Seq_HELA_Human0.97352163
95ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.97094539
96AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97053787
97DPY_21335234_ChIP-Seq_ESCs_Mouse0.96647395
98DNAJC2_21179169_ChIP-ChIP_NT2_Human0.96323822
99PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.95214094
100RNF2_27304074_Chip-Seq_NSC_Mouse0.95139687
101ESR2_21235772_ChIP-Seq_MCF-7_Human0.93721431
102MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93326383
103NRF2_20460467_ChIP-Seq_MEFs_Mouse0.91394241
104NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.91394241
105SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91350064
106ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.90800574
107TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90412625
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.90116880
109NR3C1_21868756_ChIP-Seq_MCF10A_Human0.88560427
110PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.88518388
111YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88512659
112LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87794690
113* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87348539
114RUNX2_22187159_ChIP-Seq_PCA_Human0.86633604
115KLF4_19829295_ChIP-Seq_ESCs_Human0.86412371
116PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.86154118
117DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86024837
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.84910252
119WT1_19549856_ChIP-ChIP_CCG9911_Human0.84491759
120SMAD4_21741376_ChIP-Seq_HESCs_Human0.84257552
121SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.83911158
122PRDM14_20953172_ChIP-Seq_ESCs_Human0.83809562
123KDM2B_26808549_Chip-Seq_K562_Human0.82932857
124EGR1_19032775_ChIP-ChIP_M12_Human0.82817348
125UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.82809308
126AR_19668381_ChIP-Seq_PC3_Human0.82253248
127SMAD4_21741376_ChIP-Seq_EPCs_Human0.82164126
128SMAD4_21741376_ChIP-Seq_ESCs_Human0.81996140
129EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.81517557
130TRIM28_21343339_ChIP-Seq_HEK293_Human0.81220666
131MYC_19915707_ChIP-ChIP_AK7_Human0.80908302
132EOMES_21245162_ChIP-Seq_HESCs_Human0.80901965
133CREB1_26743006_Chip-Seq_LNCaP_Human0.79209888
134SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.78807158
135KDM2B_26808549_Chip-Seq_DND41_Human0.78484541
136RUNX1_26923725_Chip-Seq_HPCs_Mouse0.77510726
137TP53_23651856_ChIP-Seq_MEFs_Mouse0.72937767
138SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.72422811
139BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.70689100
140GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.69548759
141P68_20966046_ChIP-Seq_HELA_Human0.69403175

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.76594238
2MP0004859_abnormal_synaptic_plasticity4.30793824
3MP0000920_abnormal_myelination4.23676360
4MP0004270_analgesia3.79294366
5MP0003635_abnormal_synaptic_transmissio2.97312525
6MP0002272_abnormal_nervous_system2.91577508
7MP0002064_seizures2.89499037
8MP0003329_amyloid_beta_deposits2.83838894
9MP0009046_muscle_twitch2.75073846
10MP0001486_abnormal_startle_reflex2.71028271
11MP0009745_abnormal_behavioral_response2.68271442
12MP0003690_abnormal_glial_cell2.65298842
13MP0004885_abnormal_endolymph2.60987941
14MP0005423_abnormal_somatic_nervous2.35270687
15MP0003879_abnormal_hair_cell2.28369623
16MP0002734_abnormal_mechanical_nocicepti2.25009257
17MP0003950_abnormal_plasma_membrane2.20193709
18MP0002063_abnormal_learning/memory/cond2.14419856
19MP0004742_abnormal_vestibular_system2.12965335
20MP0004142_abnormal_muscle_tone2.05841381
21MP0001529_abnormal_vocalization2.03709177
22MP0003634_abnormal_glial_cell2.02841705
23MP0001905_abnormal_dopamine_level2.01951308
24MP0000778_abnormal_nervous_system2.01121872
25MP0002572_abnormal_emotion/affect_behav1.98715326
26MP0001440_abnormal_grooming_behavior1.93855344
27MP0001968_abnormal_touch/_nociception1.82313945
28MP0001485_abnormal_pinna_reflex1.81456765
29MP0008569_lethality_at_weaning1.79744556
30MP0005171_absent_coat_pigmentation1.79321250
31MP0002229_neurodegeneration1.76478876
32MP0000955_abnormal_spinal_cord1.71937518
33MP0003787_abnormal_imprinting1.69708570
34MP0001970_abnormal_pain_threshold1.67059044
35MP0003632_abnormal_nervous_system1.65826900
36MP0002733_abnormal_thermal_nociception1.64973133
37MP0002067_abnormal_sensory_capabilities1.64067962
38MP0002822_catalepsy1.60250277
39MP0002735_abnormal_chemical_nociception1.59000749
40MP0001501_abnormal_sleep_pattern1.52214565
41MP0002882_abnormal_neuron_morphology1.51827396
42MP0001177_atelectasis1.50210188
43MP0002736_abnormal_nociception_after1.45956416
44MP0002066_abnormal_motor_capabilities/c1.44901390
45MP0000604_amyloidosis1.43766576
46MP0003631_nervous_system_phenotype1.41709827
47MP0004924_abnormal_behavior1.41693296
48MP0005386_behavior/neurological_phenoty1.41693296
49MP0003123_paternal_imprinting1.35229076
50MP0005410_abnormal_fertilization1.33882054
51MP0003633_abnormal_nervous_system1.33866844
52MP0005409_darkened_coat_color1.32521327
53MP0000462_abnormal_digestive_system1.25364056
54MP0003136_yellow_coat_color1.23761358
55MP0002184_abnormal_innervation1.23326296
56MP0005551_abnormal_eye_electrophysiolog1.22170791
57MP0010678_abnormal_skin_adnexa1.19092132
58MP0002557_abnormal_social/conspecific_i1.15237878
59MP0004145_abnormal_muscle_electrophysio1.14942968
60MP0004147_increased_porphyrin_level1.14577539
61MP0001963_abnormal_hearing_physiology1.14559421
62MP0003122_maternal_imprinting1.13621829
63MP0005623_abnormal_meninges_morphology1.13617541
64MP0004043_abnormal_pH_regulation1.13390432
65MP0001299_abnormal_eye_distance/1.12861545
66MP0004811_abnormal_neuron_physiology1.09789170
67MP0002752_abnormal_somatic_nervous1.06747761
68MP0009780_abnormal_chondrocyte_physiolo1.03740460
69MP0000383_abnormal_hair_follicle0.99294566
70MP0000747_muscle_weakness0.98774143
71MP0002295_abnormal_pulmonary_circulatio0.97670091
72MP0004782_abnormal_surfactant_physiolog0.96495746
73MP0001502_abnormal_circadian_rhythm0.96230896
74MP0002152_abnormal_brain_morphology0.93963618
75MP0004858_abnormal_nervous_system0.93862807
76MP0001958_emphysema0.93261765
77MP0003172_abnormal_lysosome_physiology0.92253146
78MP0002133_abnormal_respiratory_system0.90290618
79MP0005388_respiratory_system_phenotype0.90290618
80MP0005083_abnormal_biliary_tract0.88751861
81MP0000566_synostosis0.87814932
82MP0001346_abnormal_lacrimal_gland0.86938301
83MP0001348_abnormal_lacrimal_gland0.85273943
84MP0005646_abnormal_pituitary_gland0.81355798
85MP0001986_abnormal_taste_sensitivity0.81194514
86MP0001851_eye_inflammation0.78822601
87MP0006276_abnormal_autonomic_nervous0.78790773
88MP0002638_abnormal_pupillary_reflex0.76555542
89MP0005535_abnormal_body_temperature0.76386707
90MP0005058_abnormal_lysosome_morphology0.76330115
91MP0005645_abnormal_hypothalamus_physiol0.75496169
92MP0008260_abnormal_autophagy0.73994583
93MP0005451_abnormal_body_composition0.73018686
94MP0001943_abnormal_respiration0.72376735
95MP0008874_decreased_physiological_sensi0.70384496
96MP0001664_abnormal_digestion0.70262816
97MP0003075_altered_response_to0.69494419
98MP0002909_abnormal_adrenal_gland0.66889560
99MP0003137_abnormal_impulse_conducting0.66126407
100MP0002090_abnormal_vision0.63754460
101MP0005195_abnormal_posterior_eye0.63624013
102MP0000026_abnormal_inner_ear0.63107676
103MP0000751_myopathy0.61373513
104MP0000579_abnormal_nail_morphology0.60347001
105MP0002069_abnormal_eating/drinking_beha0.59789654
106MP0001984_abnormal_olfaction0.59686085
107MP0000639_abnormal_adrenal_gland0.59440371
108MP0004085_abnormal_heartbeat0.59193505
109MP0004381_abnormal_hair_follicle0.58407619
110MP0005167_abnormal_blood-brain_barrier0.58065998
111MP0008872_abnormal_physiological_respon0.57749378
112MP0005166_decreased_susceptibility_to0.57099369
113MP0010386_abnormal_urinary_bladder0.56663410
114MP0003283_abnormal_digestive_organ0.56397286
115MP0000569_abnormal_digit_pigmentation0.55572385
116MP0004130_abnormal_muscle_cell0.54845855
117MP0008877_abnormal_DNA_methylation0.52337095
118MP0010769_abnormal_survival0.52197778
119MP0010768_mortality/aging0.48875244
120MP0003956_abnormal_body_size0.48224808
121MP0003045_fibrosis0.47701275
122MP0001188_hyperpigmentation0.46886884
123MP0002082_postnatal_lethality0.46831823
124MP0010770_preweaning_lethality0.46831823
125MP0002089_abnormal_postnatal_growth/wei0.46640418

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)6.35296084
2Febrile seizures (HP:0002373)5.39691581
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.32637177
4Degeneration of the lateral corticospinal tracts (HP:0002314)5.32637177
5Myokymia (HP:0002411)5.15254505
6Diplopia (HP:0000651)4.98841475
7Abnormality of binocular vision (HP:0011514)4.98841475
8Supranuclear gaze palsy (HP:0000605)4.94771489
9Cerebral inclusion bodies (HP:0100314)4.72335205
10Sensory axonal neuropathy (HP:0003390)4.38275178
11Abnormality of the corticospinal tract (HP:0002492)4.36301834
12Peripheral hypomyelination (HP:0007182)4.21654421
13Focal motor seizures (HP:0011153)3.97418604
14Dysmetria (HP:0001310)3.87037581
15Spastic gait (HP:0002064)3.85361454
16Intention tremor (HP:0002080)3.82588997
17Annular pancreas (HP:0001734)3.68757181
18Tetraplegia (HP:0002445)3.56244804
19Obstructive sleep apnea (HP:0002870)3.55061098
20Ankle clonus (HP:0011448)3.54261408
21Torticollis (HP:0000473)3.53534626
22Papilledema (HP:0001085)3.50507950
23Cerebral hypomyelination (HP:0006808)3.50448462
24Onion bulb formation (HP:0003383)3.48680052
25Parakeratosis (HP:0001036)3.40363834
26Atonic seizures (HP:0010819)3.39422838
27Action tremor (HP:0002345)3.38549200
28Scanning speech (HP:0002168)3.36521292
29Limb dystonia (HP:0002451)3.36496001
30Hemiplegia (HP:0002301)3.31797192
31Alacrima (HP:0000522)3.12079928
32Depression (HP:0000716)3.06884789
33Focal dystonia (HP:0004373)3.03862251
34Focal seizures (HP:0007359)3.03612415
35Delusions (HP:0000746)3.02814576
36Status epilepticus (HP:0002133)2.92351028
37Slow saccadic eye movements (HP:0000514)2.83665295
38Termporal pattern (HP:0011008)2.83596922
39Insidious onset (HP:0003587)2.83596922
40Thickened helices (HP:0000391)2.83015254
41Megalencephaly (HP:0001355)2.80893292
42Craniofacial dystonia (HP:0012179)2.79961105
43Bradykinesia (HP:0002067)2.79056235
44Epileptic encephalopathy (HP:0200134)2.77546747
45Akinesia (HP:0002304)2.74600817
46Poor eye contact (HP:0000817)2.69491403
47Apathy (HP:0000741)2.66884772
48Abnormal auditory evoked potentials (HP:0006958)2.66314768
49Epileptiform EEG discharges (HP:0011182)2.63594611
50Rigidity (HP:0002063)2.60033167
51Progressive cerebellar ataxia (HP:0002073)2.59315885
52Hemiparesis (HP:0001269)2.59065285
53Aplasia involving bones of the extremities (HP:0009825)2.58537120
54Aplasia involving bones of the upper limbs (HP:0009823)2.58537120
55Aplasia of the phalanges of the hand (HP:0009802)2.58537120
56Insomnia (HP:0100785)2.55241731
57Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.53225574
58Sleep apnea (HP:0010535)2.48946537
59Split foot (HP:0001839)2.48856196
60Gaze-evoked nystagmus (HP:0000640)2.46031106
61Pheochromocytoma (HP:0002666)2.44070054
62Retinal dysplasia (HP:0007973)2.43253454
63Dysdiadochokinesis (HP:0002075)2.42272504
64Lower limb muscle weakness (HP:0007340)2.42266590
65Cerebral hemorrhage (HP:0001342)2.40705650
66Diminished motivation (HP:0000745)2.40201758
67Impaired smooth pursuit (HP:0007772)2.37136067
68Anteriorly placed anus (HP:0001545)2.36314315
69Decreased lacrimation (HP:0000633)2.35972791
70Ocular albinism (HP:0001107)2.35142772
71Abnormality of the lower motor neuron (HP:0002366)2.34538197
72EEG with generalized epileptiform discharges (HP:0011198)2.29685934
73Urinary urgency (HP:0000012)2.29094054
74Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.27094470
75Iris hypopigmentation (HP:0007730)2.25612223
76Synostosis involving the elbow (HP:0003938)2.25206067
77Humeroradial synostosis (HP:0003041)2.25206067
78Abnormal social behavior (HP:0012433)2.24881078
79Impaired social interactions (HP:0000735)2.24881078
80Amblyopia (HP:0000646)2.24397648
81Premature skin wrinkling (HP:0100678)2.22440772
82Spastic tetraparesis (HP:0001285)2.22390302
83Dialeptic seizures (HP:0011146)2.21955114
84Broad-based gait (HP:0002136)2.21557236
85Ventricular fibrillation (HP:0001663)2.20741155
86Increased circulating renin level (HP:0000848)2.20571583
87Clumsiness (HP:0002312)2.19160946
88Impaired vibratory sensation (HP:0002495)2.17694871
89Abnormality of ocular smooth pursuit (HP:0000617)2.17597814
90Stereotypic behavior (HP:0000733)2.17029826
91Spastic paraparesis (HP:0002313)2.16482034
92Bundle branch block (HP:0011710)2.15649923
93Postural instability (HP:0002172)2.14446430
94Leukodystrophy (HP:0002415)2.14428086
95Clonus (HP:0002169)2.14195584
96Hypsarrhythmia (HP:0002521)2.13133016
97CNS hypomyelination (HP:0003429)2.12930326
98Absence seizures (HP:0002121)2.10247184
99Anxiety (HP:0000739)2.08712515
100Neuroendocrine neoplasm (HP:0100634)2.08491806
101Visual hallucinations (HP:0002367)2.06025749
102Abnormality of the periventricular white matter (HP:0002518)2.03947685
103Urinary bladder sphincter dysfunction (HP:0002839)2.03004935
104Lower limb asymmetry (HP:0100559)2.02196879
105Foot dorsiflexor weakness (HP:0009027)2.01819089
106Generalized myoclonic seizures (HP:0002123)1.99945475
107Abnormality of saccadic eye movements (HP:0000570)1.97534350
108Morphological abnormality of the inner ear (HP:0011390)1.97277995
109Autoamputation (HP:0001218)1.96702830
110Neuronal loss in central nervous system (HP:0002529)1.95909144
111Poor speech (HP:0002465)1.94983204
112Truncal ataxia (HP:0002078)1.94847964
113Incomplete penetrance (HP:0003829)1.94827131
114Abnormal eating behavior (HP:0100738)1.93711748
115Generalized tonic-clonic seizures (HP:0002069)1.93102336
116Segmental peripheral demyelination/remyelination (HP:0003481)1.93072444
117Spinal canal stenosis (HP:0003416)1.92940266
118Bowel incontinence (HP:0002607)1.91470437
119Hammertoe (HP:0001765)1.90385500
120Lower limb amyotrophy (HP:0007210)1.90323609
121Memory impairment (HP:0002354)1.90211460
122Choreoathetosis (HP:0001266)1.88895612
123Decreased motor nerve conduction velocity (HP:0003431)1.87942785
124Hypokalemic alkalosis (HP:0001949)1.87379294
125Absent septum pellucidum (HP:0001331)1.86597710
126Metabolic alkalosis (HP:0200114)1.86188285
127Stridor (HP:0010307)1.85763844
128Progressive inability to walk (HP:0002505)1.84668962
129Heterochromia iridis (HP:0001100)1.84393277
130Coronal craniosynostosis (HP:0004440)1.84181905
131Morphological abnormality of the pyramidal tract (HP:0002062)1.84090182
132Distal sensory impairment (HP:0002936)1.83494211
133Polyphagia (HP:0002591)1.83204016
134Abnormality of the foot musculature (HP:0001436)1.81770122
135Dementia (HP:0000726)1.80932020
136Interstitial pulmonary disease (HP:0006530)1.80574391
137Loss of speech (HP:0002371)1.79105729
138Heart block (HP:0012722)1.78580848
139Impaired vibration sensation in the lower limbs (HP:0002166)1.77946008
140Abnormality of the phalanges of the 2nd finger (HP:0009541)1.77351111
141Mutism (HP:0002300)1.76974741
142Renal salt wasting (HP:0000127)1.75643299
143Abnormal large intestine physiology (HP:0012700)1.74596866
144Slow progression (HP:0003677)1.74243903
145Hypomagnesemia (HP:0002917)1.72744609
146Rapidly progressive (HP:0003678)1.72494451
147Urinary incontinence (HP:0000020)1.72188046
148Partial agenesis of the corpus callosum (HP:0001338)1.70982929

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.12759746
2OXSR14.06943177
3CDK193.02386708
4EPHA42.60169787
5EPHB12.41478311
6FGFR22.35619879
7BCR2.30441305
8WNK12.22864996
9WNK42.20188733
10PRPF4B2.19967858
11NTRK12.12300910
12TNIK2.09983914
13PKN12.04425638
14MAP3K92.03816254
15NTRK31.92599840
16PAK61.83971142
17UHMK11.82050412
18LIMK11.79347181
19RIPK41.78545702
20RIPK11.74638269
21NEK61.73288748
22PNCK1.69356994
23MET1.67137559
24LATS21.53001508
25TYRO31.49504179
26CSNK1G31.48995101
27ICK1.48913213
28MARK11.46366475
29CAMK2B1.46128772
30MAPKAPK51.45603723
31ROCK21.44431025
32DAPK11.42181981
33CSNK1A1L1.41512559
34KSR21.37244744
35CSNK1G21.33286654
36CASK1.24267953
37CDK51.21841439
38SGK4941.20759102
39SGK2231.20759102
40MINK11.17534852
41ARAF1.17529697
42CAMK2D1.13822763
43FGR1.12169962
44CSNK1G11.08584767
45SIK21.08368810
46DAPK21.05451037
47PBK1.05168129
48NTRK21.04676049
49CAMK2G1.03458604
50MAP3K41.03205860
51STK380.97727934
52CDK140.97465638
53PHKG10.97317526
54PHKG20.97317526
55DYRK1A0.97051303
56MARK20.96285734
57SGK20.93812293
58PAK30.93682815
59MAPK120.93667002
60PDPK10.92552187
61CAMK2A0.92101695
62CDK150.88597747
63PRKD30.87699394
64FES0.86880437
65BRSK10.86193462
66MAP3K20.85781411
67SGK30.85470323
68MAP3K130.84282596
69CDK180.84163435
70CLK10.82722818
71PRKCH0.81115136
72BMPR20.79637626
73CDK11A0.78206783
74SGK10.77066168
75MAP3K110.75064463
76PRKCQ0.72228250
77STK110.70985815
78PRKD10.66330351
79FYN0.65275185
80MAPK130.64649977
81PINK10.63340222
82LMTK20.63178941
83CAMK40.63156825
84MAP2K70.62636555
85PRKCE0.60726379
86PDK10.59376375
87MUSK0.58627311
88MAPK150.58332427
89RPS6KA30.58187580
90GRK50.57984630
91TNK20.57908482
92CAMK1G0.56496291
93BRAF0.56449860
94TESK20.52116181
95PDGFRB0.50697121
96PRKCG0.50665433
97CAMKK10.49350919
98CAMKK20.47668354
99PTK2B0.46866749
100MST40.46723710
101MAP2K40.45021942
102PRKG20.44113435
103PRKCZ0.42011774
104RAF10.41511569
105RET0.40717831
106CAMK10.40598132
107IRAK20.40523507
108CSNK1A10.40061627
109TESK10.39594599
110PRKG10.39230180
111DMPK0.38732218
112MAP2K60.38517783
113BMX0.38093435
114MAPK100.37241617
115PRKACB0.36064611
116DAPK30.35379177
117PLK20.35337184
118CSNK1D0.35036298
119ROCK10.34984631
120PRKCA0.34673069
121ALK0.34614174
122MAP3K10.34333992
123KSR10.33123221
124DDR20.32798410
125ERBB20.32512576
126MAP3K120.32500409
127SRC0.26704163
128PRKCB0.25614115
129MAPK80.25109739
130JAK20.23691751
131CCNB10.22860828

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.10852346
2Fatty acid elongation_Homo sapiens_hsa000622.70944432
3Steroid biosynthesis_Homo sapiens_hsa001002.48750319
4Nicotine addiction_Homo sapiens_hsa050332.32039371
5GABAergic synapse_Homo sapiens_hsa047272.25381273
6Synaptic vesicle cycle_Homo sapiens_hsa047212.23519948
7Ether lipid metabolism_Homo sapiens_hsa005652.18676300
8Glutamatergic synapse_Homo sapiens_hsa047242.13783213
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.97978446
10Morphine addiction_Homo sapiens_hsa050321.96505181
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.92335510
12Axon guidance_Homo sapiens_hsa043601.89967475
13Circadian entrainment_Homo sapiens_hsa047131.79632613
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.72273974
15Salivary secretion_Homo sapiens_hsa049701.69232989
16Serotonergic synapse_Homo sapiens_hsa047261.57944879
17Long-term depression_Homo sapiens_hsa047301.55591255
18Gastric acid secretion_Homo sapiens_hsa049711.55123185
19Olfactory transduction_Homo sapiens_hsa047401.53209957
20Collecting duct acid secretion_Homo sapiens_hsa049661.50558152
21Long-term potentiation_Homo sapiens_hsa047201.46546694
22Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.45388951
23Nitrogen metabolism_Homo sapiens_hsa009101.45242427
24Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.43866925
25Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.42315198
26Dopaminergic synapse_Homo sapiens_hsa047281.40314989
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.38635939
28Amphetamine addiction_Homo sapiens_hsa050311.38290884
29Cholinergic synapse_Homo sapiens_hsa047251.33914219
30Cocaine addiction_Homo sapiens_hsa050301.33448948
31Sphingolipid metabolism_Homo sapiens_hsa006001.32614212
32Taste transduction_Homo sapiens_hsa047421.31393981
33Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.30679057
34Vibrio cholerae infection_Homo sapiens_hsa051101.28348744
35Oxidative phosphorylation_Homo sapiens_hsa001901.26969716
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25172219
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22254017
38Glioma_Homo sapiens_hsa052141.16745810
39Renin secretion_Homo sapiens_hsa049241.11177527
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09390903
41Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.06677219
42Cardiac muscle contraction_Homo sapiens_hsa042601.06313314
43Renal cell carcinoma_Homo sapiens_hsa052111.05810900
44Phospholipase D signaling pathway_Homo sapiens_hsa040721.04935239
45Insulin secretion_Homo sapiens_hsa049111.04400772
46Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.04066246
47Gap junction_Homo sapiens_hsa045400.99052172
48Vascular smooth muscle contraction_Homo sapiens_hsa042700.98924633
49Alzheimers disease_Homo sapiens_hsa050100.98799161
50Dorso-ventral axis formation_Homo sapiens_hsa043200.98240362
51Endocytosis_Homo sapiens_hsa041440.98164697
52Oxytocin signaling pathway_Homo sapiens_hsa049210.97704723
53Sphingolipid signaling pathway_Homo sapiens_hsa040710.95838514
54cAMP signaling pathway_Homo sapiens_hsa040240.95778176
55ErbB signaling pathway_Homo sapiens_hsa040120.94805924
56Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94693416
57Vitamin B6 metabolism_Homo sapiens_hsa007500.93211755
58Aldosterone synthesis and secretion_Homo sapiens_hsa049250.92666563
59Tight junction_Homo sapiens_hsa045300.92647486
60Calcium signaling pathway_Homo sapiens_hsa040200.92031595
61Pancreatic secretion_Homo sapiens_hsa049720.90698559
62Mineral absorption_Homo sapiens_hsa049780.90677800
63Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.88396574
64Oocyte meiosis_Homo sapiens_hsa041140.87489071
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86493343
66Parkinsons disease_Homo sapiens_hsa050120.83631293
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.82869285
68GnRH signaling pathway_Homo sapiens_hsa049120.82735999
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82185856
70Butanoate metabolism_Homo sapiens_hsa006500.79799660
71Ras signaling pathway_Homo sapiens_hsa040140.77771521
72Glycerophospholipid metabolism_Homo sapiens_hsa005640.77603383
73Sulfur metabolism_Homo sapiens_hsa009200.74932183
74Fatty acid biosynthesis_Homo sapiens_hsa000610.74597344
75Lysosome_Homo sapiens_hsa041420.72559093
76VEGF signaling pathway_Homo sapiens_hsa043700.72523053
77Ovarian steroidogenesis_Homo sapiens_hsa049130.71552761
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.71074203
79Phototransduction_Homo sapiens_hsa047440.70608272
80Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.69286135
81Choline metabolism in cancer_Homo sapiens_hsa052310.65859988
82Rheumatoid arthritis_Homo sapiens_hsa053230.65685199
83Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.63197270
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.62442665
85Linoleic acid metabolism_Homo sapiens_hsa005910.62438391
86Melanogenesis_Homo sapiens_hsa049160.61766187
87Histidine metabolism_Homo sapiens_hsa003400.61702714
88Glucagon signaling pathway_Homo sapiens_hsa049220.59629146
89Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58910599
90Estrogen signaling pathway_Homo sapiens_hsa049150.56454529
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.56126788
92MAPK signaling pathway_Homo sapiens_hsa040100.55157542
93Arginine and proline metabolism_Homo sapiens_hsa003300.54554685
94Thyroid hormone synthesis_Homo sapiens_hsa049180.54000308
95Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.53924878
96cGMP-PKG signaling pathway_Homo sapiens_hsa040220.52664664
97Prion diseases_Homo sapiens_hsa050200.52118081
98Phagosome_Homo sapiens_hsa041450.51906897
99Arginine biosynthesis_Homo sapiens_hsa002200.50153932
100Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50016316
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49617928
102beta-Alanine metabolism_Homo sapiens_hsa004100.49139187
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48742504
104Circadian rhythm_Homo sapiens_hsa047100.48459201
105Inositol phosphate metabolism_Homo sapiens_hsa005620.46689601
106Dilated cardiomyopathy_Homo sapiens_hsa054140.46291006
107Rap1 signaling pathway_Homo sapiens_hsa040150.44822118
108Bile secretion_Homo sapiens_hsa049760.42499965
109Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40894070
110Hedgehog signaling pathway_Homo sapiens_hsa043400.38989874
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.38875466
112Type II diabetes mellitus_Homo sapiens_hsa049300.38383532
113mTOR signaling pathway_Homo sapiens_hsa041500.35349032
114Protein export_Homo sapiens_hsa030600.34697151
115Chemokine signaling pathway_Homo sapiens_hsa040620.32248095
116Alcoholism_Homo sapiens_hsa050340.32207542
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.28032411
118Wnt signaling pathway_Homo sapiens_hsa043100.27049420
119Insulin signaling pathway_Homo sapiens_hsa049100.26841214
120Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.26682738
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.24731520
122AMPK signaling pathway_Homo sapiens_hsa041520.23793865
123HIF-1 signaling pathway_Homo sapiens_hsa040660.22335328
124Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.15793314

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