LIMCH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)5.17923345
2central nervous system myelination (GO:0022010)5.17923345
3actin-myosin filament sliding (GO:0033275)3.88334617
4muscle filament sliding (GO:0030049)3.88334617
5negative regulation of protein localization to cell surface (GO:2000009)3.72493747
6ensheathment of neurons (GO:0007272)3.62755239
7axon ensheathment (GO:0008366)3.62755239
8myelination (GO:0042552)3.59115562
9membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.53533097
10actin-mediated cell contraction (GO:0070252)3.39164905
11peptidyl-tyrosine autophosphorylation (GO:0038083)3.18229467
12negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.11146559
13neuron cell-cell adhesion (GO:0007158)3.09302224
14vocalization behavior (GO:0071625)3.08391177
15neuronal action potential propagation (GO:0019227)3.05462559
16presynaptic membrane assembly (GO:0097105)3.04866295
17presynaptic membrane organization (GO:0097090)3.02955239
18regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.02461602
19regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.00204252
20regulation of dendritic spine morphogenesis (GO:0061001)2.97603922
21apical protein localization (GO:0045176)2.92518979
22response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.91785710
23positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.91181839
24potassium ion import (GO:0010107)2.87575900
25asymmetric protein localization (GO:0008105)2.87247200
26regulation of cell communication by electrical coupling (GO:0010649)2.85692674
27neuron recognition (GO:0008038)2.85650499
28regulation of membrane repolarization (GO:0060306)2.85424338
29establishment of mitochondrion localization (GO:0051654)2.84779550
30regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.84704719
31fatty acid elongation (GO:0030497)2.84609908
32macroautophagy (GO:0016236)2.83092198
33synaptic vesicle maturation (GO:0016188)2.82796166
34negative regulation of neurotransmitter secretion (GO:0046929)2.82494840
35dendritic spine morphogenesis (GO:0060997)2.81083212
36regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.80840404
37regulation of synapse structural plasticity (GO:0051823)2.80537058
38cerebral cortex radially oriented cell migration (GO:0021799)2.80136568
39negative regulation of potassium ion transmembrane transport (GO:1901380)2.79921114
40regulation of type B pancreatic cell apoptotic process (GO:2000674)2.79560940
41locomotory exploration behavior (GO:0035641)2.78503144
42creatine metabolic process (GO:0006600)2.77868170
43cardiac myofibril assembly (GO:0055003)2.76494208
44positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.76027853
45positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.75314048
46regulation of actin filament-based movement (GO:1903115)2.75145953
47regulation of short-term neuronal synaptic plasticity (GO:0048172)2.75102428
48carnitine shuttle (GO:0006853)2.75038379
49layer formation in cerebral cortex (GO:0021819)2.74919125
50cardiac muscle contraction (GO:0060048)2.74792605
51regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.73903875
52photoreceptor cell differentiation (GO:0046530)2.70725317
53eye photoreceptor cell differentiation (GO:0001754)2.70725317
54negative regulation of neurotransmitter transport (GO:0051589)2.70053416
55positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.69586392
56transmission of nerve impulse (GO:0019226)2.69145292
57regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.68758911
58membrane assembly (GO:0071709)2.68683212
59myofibril assembly (GO:0030239)2.66809840
60myelination in peripheral nervous system (GO:0022011)2.66469860
61peripheral nervous system axon ensheathment (GO:0032292)2.66469860
62striated muscle contraction (GO:0006941)2.66460031
63neuronal ion channel clustering (GO:0045161)2.65474355
64sarcomere organization (GO:0045214)2.65102148
65axonal fasciculation (GO:0007413)2.64917469
66actin filament-based movement (GO:0030048)2.64143834
67L-amino acid import (GO:0043092)2.64009114
68regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.63124906
69long-chain fatty acid biosynthetic process (GO:0042759)2.62571953
70cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.62124149
71auditory behavior (GO:0031223)2.60546013
72* actomyosin structure organization (GO:0031032)2.60475834
73positive regulation of action potential (GO:0045760)2.59672106
74dendrite morphogenesis (GO:0048813)2.59413300
75positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.57220917
76positive regulation of vascular permeability (GO:0043117)2.57066823
77regulation of dendritic spine development (GO:0060998)2.56938266
78positive regulation of potassium ion transport (GO:0043268)2.55769712
79regulation of cardiac muscle cell contraction (GO:0086004)2.54810485
80cerebellar granule cell differentiation (GO:0021707)2.54361930
81synaptic vesicle docking involved in exocytosis (GO:0016081)2.54355933
82cellular potassium ion homeostasis (GO:0030007)2.53025901
83sarcoplasmic reticulum calcium ion transport (GO:0070296)2.52370911
84regulation of voltage-gated calcium channel activity (GO:1901385)2.51759254
85glutamate secretion (GO:0014047)2.51487634
86positive regulation of potassium ion transmembrane transport (GO:1901381)2.51445190
87cell communication involved in cardiac conduction (GO:0086065)2.50440089
88cellular response to epinephrine stimulus (GO:0071872)2.48563131
89positive regulation of dendritic spine development (GO:0060999)2.47971346
90ionotropic glutamate receptor signaling pathway (GO:0035235)2.47930862
91cell communication by electrical coupling (GO:0010644)2.46552165
92astrocyte development (GO:0014002)2.45216416
93potassium ion homeostasis (GO:0055075)2.45130892
94adult walking behavior (GO:0007628)2.45102685
95regulation of skeletal muscle contraction (GO:0014819)2.44658219
96membrane tubulation (GO:0097320)2.44566090
97negative regulation of cytosolic calcium ion concentration (GO:0051481)2.44513696
98plasma membrane repair (GO:0001778)2.44420897
99peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.43935239
100synaptic vesicle exocytosis (GO:0016079)2.43258579
101detection of calcium ion (GO:0005513)2.42893184
102myelin maintenance (GO:0043217)2.40664206
103heart trabecula formation (GO:0060347)2.39938954
104neuron remodeling (GO:0016322)2.38686073
105regulation of relaxation of muscle (GO:1901077)2.38029502
106myotube differentiation (GO:0014902)2.37646348
107response to epinephrine (GO:0071871)2.37272920
108fatty acid transmembrane transport (GO:1902001)2.36962225
109glutamate receptor signaling pathway (GO:0007215)2.36771392
110protein localization to synapse (GO:0035418)2.36338395
111cellular response to monoamine stimulus (GO:0071868)2.35929071
112cellular response to catecholamine stimulus (GO:0071870)2.35929071
113cyclic nucleotide catabolic process (GO:0009214)2.35845397
114regulation of glutamate receptor signaling pathway (GO:1900449)2.35203385
115regulation of calcium ion transmembrane transport (GO:1903169)2.34213267
116regulation of calcium ion transmembrane transporter activity (GO:1901019)2.34213267
117protein localization to endosome (GO:0036010)2.33971151
118regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.33117507
119nerve growth factor signaling pathway (GO:0038180)2.32890675
120regulation of striated muscle contraction (GO:0006942)2.32772385
121regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.30654706
122relaxation of cardiac muscle (GO:0055119)2.27432998
123regulation of sodium ion transmembrane transport (GO:1902305)2.25872390
124cardiac muscle cell action potential (GO:0086001)2.25829911
125neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.24943122
126auditory receptor cell differentiation (GO:0042491)2.24145053
127brain morphogenesis (GO:0048854)2.23261444
128astrocyte differentiation (GO:0048708)2.22234119
129cardiac muscle cell action potential involved in contraction (GO:0086002)2.20383294
130muscle contraction (GO:0006936)2.19947282
131positive regulation of sodium ion transport (GO:0010765)2.19797785
132inositol phosphate catabolic process (GO:0071545)2.19739591
133regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.19535198
134positive regulation of glycolytic process (GO:0045821)2.19045160
135negative regulation of dendrite development (GO:2000171)2.18838280
136startle response (GO:0001964)2.17728180
137cardiac conduction (GO:0061337)2.17456452
138cAMP catabolic process (GO:0006198)2.16753466
139embryonic retina morphogenesis in camera-type eye (GO:0060059)2.16227745
140regulation of sodium ion transmembrane transporter activity (GO:2000649)2.15455453
141cardiac muscle hypertrophy (GO:0003300)2.14101846
142negative regulation of complement activation (GO:0045916)2.13784009
143glycogen catabolic process (GO:0005980)2.13597377
144regulation of protein glycosylation (GO:0060049)2.12427331
145negative regulation of vascular permeability (GO:0043116)2.11582784
146positive regulation of cation channel activity (GO:2001259)2.11161301
147regulation of potassium ion transmembrane transporter activity (GO:1901016)2.10207239
148relaxation of muscle (GO:0090075)2.09682844
149cellular sodium ion homeostasis (GO:0006883)2.09392823
150adrenergic receptor signaling pathway (GO:0071875)2.09207416
151establishment of nucleus localization (GO:0040023)2.09206341
152skeletal muscle contraction (GO:0003009)2.08986644
153cAMP-mediated signaling (GO:0019933)2.08661156
154ventricular cardiac muscle cell action potential (GO:0086005)2.08544275
155response to inactivity (GO:0014854)2.07599646
156neurotransmitter-gated ion channel clustering (GO:0072578)2.06916978
157cellular ketone body metabolic process (GO:0046950)2.06337265
158myoblast fusion (GO:0007520)2.05155327
159muscle cell cellular homeostasis (GO:0046716)2.05028929

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.16466718
2GBX2_23144817_ChIP-Seq_PC3_Human2.98155915
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.95843770
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.74358922
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.66659845
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.52980018
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.45525758
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.45525758
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40118891
10* EZH2_27304074_Chip-Seq_ESCs_Mouse2.31110209
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.26066145
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.24893528
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.22477191
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.20070958
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.16992718
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.08854034
17DROSHA_22980978_ChIP-Seq_HELA_Human2.05817642
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.02362047
19SUZ12_27294783_Chip-Seq_ESCs_Mouse1.94554787
20* RNF2_27304074_Chip-Seq_ESCs_Mouse1.89578109
21EP300_21415370_ChIP-Seq_HL-1_Mouse1.88714697
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.83266399
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.83147456
24AR_21572438_ChIP-Seq_LNCaP_Human1.67631099
25BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.62088079
26* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.61898589
27PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56431691
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.55378425
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.53467846
30RARB_27405468_Chip-Seq_BRAIN_Mouse1.52332578
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.49631775
32TAF15_26573619_Chip-Seq_HEK293_Human1.49469813
33MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.48331782
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47148951
35RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46607235
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.46531228
37REST_21632747_ChIP-Seq_MESCs_Mouse1.44271670
38IGF1R_20145208_ChIP-Seq_DFB_Human1.41789253
39* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.41623885
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.41153426
41* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41018707
42FUS_26573619_Chip-Seq_HEK293_Human1.40578185
43AHR_22903824_ChIP-Seq_MCF-7_Human1.36842217
44TRIM28_21343339_ChIP-Seq_HEK293_Human1.33020557
45CJUN_26792858_Chip-Seq_BT549_Human1.31940542
46* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31525737
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.31482022
48ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.29804658
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29753381
50* SMAD4_21799915_ChIP-Seq_A2780_Human1.28950000
51* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.28916039
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.28746968
53ARNT_22903824_ChIP-Seq_MCF-7_Human1.28285205
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28092785
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27723687
56CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27606226
57TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27418873
58WT1_25993318_ChIP-Seq_PODOCYTE_Human1.27168710
59EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.27000711
60SALL1_21062744_ChIP-ChIP_HESCs_Human1.23051315
61SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.22607017
62* NANOG_18555785_Chip-Seq_ESCs_Mouse1.21678345
63RING1B_27294783_Chip-Seq_ESCs_Mouse1.21558769
64REST_18959480_ChIP-ChIP_MESCs_Mouse1.20886520
65NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.20756405
66ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.20563357
67RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19758524
68GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18319390
69SOX2_21211035_ChIP-Seq_LN229_Gbm1.14901101
70CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14813782
71RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.12612681
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.11885918
73NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11395104
74ERG_21242973_ChIP-ChIP_JURKAT_Human1.11266267
75* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10233754
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.09780061
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09284403
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09261387
79* STAT3_23295773_ChIP-Seq_U87_Human1.08628989
80TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.08231651
81P300_19829295_ChIP-Seq_ESCs_Human1.07498331
82SUZ12_27294783_Chip-Seq_NPCs_Mouse1.07212519
83ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.06546421
84ZNF274_21170338_ChIP-Seq_K562_Hela1.05777928
85EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05602207
86CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.04993900
87CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.04564852
88PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03072946
89EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03019741
90P53_22387025_ChIP-Seq_ESCs_Mouse1.02997323
91* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.02727295
92VDR_22108803_ChIP-Seq_LS180_Human1.02626386
93BCAT_22108803_ChIP-Seq_LS180_Human1.02618152
94VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.02247340
95TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02190325
96STAT6_21828071_ChIP-Seq_BEAS2B_Human1.01209566
97SMAD3_21741376_ChIP-Seq_HESCs_Human1.01105308
98FLI1_27457419_Chip-Seq_LIVER_Mouse1.00825927
99POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00562223
100MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.00333543
101* TCF4_23295773_ChIP-Seq_U87_Human1.00117032
102LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00013285
103E2F1_18555785_Chip-Seq_ESCs_Mouse0.99114041
104* SMAD4_21741376_ChIP-Seq_HESCs_Human0.98856890
105EZH2_27294783_Chip-Seq_NPCs_Mouse0.98340899
106AR_19668381_ChIP-Seq_PC3_Human0.98326477
107EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98121035
108P53_22127205_ChIP-Seq_FIBROBLAST_Human0.98007003
109IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97860654
110CBP_20019798_ChIP-Seq_JUKART_Human0.97860654
111WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97531127
112STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97020430
113PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.96946423
114PCGF2_27294783_Chip-Seq_ESCs_Mouse0.96740279
115ESR2_21235772_ChIP-Seq_MCF-7_Human0.95976528
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95838286
117TP53_16413492_ChIP-PET_HCT116_Human0.95717405
118UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94815231
119AR_25329375_ChIP-Seq_VCAP_Human0.94565192
120ER_23166858_ChIP-Seq_MCF-7_Human0.93714491
121* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92137248
122TP53_18474530_ChIP-ChIP_U2OS_Human0.90461873
123NRF2_20460467_ChIP-Seq_MEFs_Mouse0.89371867
124NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.89371867
125WT1_19549856_ChIP-ChIP_CCG9911_Human0.89015940
126RUNX2_22187159_ChIP-Seq_PCA_Human0.88619762
127SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.88614574
128BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.87835911
129RNF2_27304074_Chip-Seq_NSC_Mouse0.87499211
130MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.87070695
131* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87060258

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.24478154
2MP0000751_myopathy2.99622078
3MP0003880_abnormal_central_pattern2.87082336
4MP0002837_dystrophic_cardiac_calcinosis2.84418654
5MP0004270_analgesia2.79785959
6MP0000920_abnormal_myelination2.34797719
7MP0004215_abnormal_myocardial_fiber2.29975617
8MP0003635_abnormal_synaptic_transmissio2.29514662
9MP0004084_abnormal_cardiac_muscle2.19569668
10MP0004036_abnormal_muscle_relaxation2.15157242
11MP0001486_abnormal_startle_reflex2.11632570
12MP0004885_abnormal_endolymph2.10795172
13MP0003950_abnormal_plasma_membrane2.09153020
14MP0004145_abnormal_muscle_electrophysio2.04096306
15MP0002272_abnormal_nervous_system1.99070690
16MP0002064_seizures1.95008812
17MP0003137_abnormal_impulse_conducting1.94536608
18MP0009745_abnormal_behavioral_response1.92329953
19MP0002822_catalepsy1.91512720
20MP0000749_muscle_degeneration1.84760685
21MP0009046_muscle_twitch1.84623835
22MP0000778_abnormal_nervous_system1.84345129
23MP0002638_abnormal_pupillary_reflex1.82745612
24MP0002734_abnormal_mechanical_nocicepti1.81234001
25MP0002063_abnormal_learning/memory/cond1.76546354
26MP0009780_abnormal_chondrocyte_physiolo1.76212035
27MP0005171_absent_coat_pigmentation1.68255012
28MP0005409_darkened_coat_color1.66999710
29MP0005330_cardiomyopathy1.66164069
30MP0004085_abnormal_heartbeat1.63750442
31MP0005423_abnormal_somatic_nervous1.62755533
32MP0004484_altered_response_of1.62119172
33MP0006138_congestive_heart_failure1.61994898
34MP0000003_abnormal_adipose_tissue1.61606555
35MP0003329_amyloid_beta_deposits1.60715103
36MP0003283_abnormal_digestive_organ1.58797113
37MP0005187_abnormal_penis_morphology1.58114381
38MP0003646_muscle_fatigue1.57756734
39MP0002572_abnormal_emotion/affect_behav1.54673108
40MP0001984_abnormal_olfaction1.52361764
41MP0005620_abnormal_muscle_contractility1.51586315
42MP0000747_muscle_weakness1.50509536
43MP0003690_abnormal_glial_cell1.49765890
44MP0004272_abnormal_basement_membrane1.49198265
45MP0001440_abnormal_grooming_behavior1.48651796
46MP0005623_abnormal_meninges_morphology1.47503722
47MP0010234_abnormal_vibrissa_follicle1.46451596
48MP0003634_abnormal_glial_cell1.46189682
49MP0002972_abnormal_cardiac_muscle1.45010158
50MP0001485_abnormal_pinna_reflex1.43932777
51MP0005167_abnormal_blood-brain_barrier1.40672124
52MP0004087_abnormal_muscle_fiber1.38980671
53MP0008569_lethality_at_weaning1.38627815
54MP0010368_abnormal_lymphatic_system1.37159350
55MP0001968_abnormal_touch/_nociception1.35163811
56MP0003136_yellow_coat_color1.30333597
57MP0004742_abnormal_vestibular_system1.29091936
58MP0002067_abnormal_sensory_capabilities1.27553690
59MP0005646_abnormal_pituitary_gland1.26839361
60MP0001879_abnormal_lymphatic_vessel1.26824123
61MP0001970_abnormal_pain_threshold1.25517254
62MP0005386_behavior/neurological_phenoty1.24284030
63MP0004924_abnormal_behavior1.24284030
64MP0002735_abnormal_chemical_nociception1.23251092
65MP0002106_abnormal_muscle_physiology1.20844692
66MP0001529_abnormal_vocalization1.18550029
67MP0002882_abnormal_neuron_morphology1.17877054
68MP0000955_abnormal_spinal_cord1.17340640
69MP0004043_abnormal_pH_regulation1.17138905
70MP0002733_abnormal_thermal_nociception1.16122164
71MP0005369_muscle_phenotype1.15203674
72MP0002332_abnormal_exercise_endurance1.14589553
73MP0005385_cardiovascular_system_phenoty1.13361816
74MP0001544_abnormal_cardiovascular_syste1.13361816
75MP0001958_emphysema1.12917340
76MP0008775_abnormal_heart_ventricle1.10188965
77MP0010386_abnormal_urinary_bladder1.10088900
78MP0001905_abnormal_dopamine_level1.09588576
79MP0002184_abnormal_innervation1.09547129
80MP0004130_abnormal_muscle_cell1.08823761
81MP0004233_abnormal_muscle_weight1.08644564
82MP0002066_abnormal_motor_capabilities/c1.08092501
83MP0003633_abnormal_nervous_system1.07305661
84MP0002229_neurodegeneration1.06828273
85MP0001177_atelectasis1.06782235
86MP0001502_abnormal_circadian_rhythm1.06758379
87MP0006276_abnormal_autonomic_nervous1.06462222
88MP0003879_abnormal_hair_cell1.03899187
89MP0005551_abnormal_eye_electrophysiolog1.03776732
90MP0002557_abnormal_social/conspecific_i1.03713271
91MP0003195_calcinosis1.03566467
92MP0003631_nervous_system_phenotype1.03411535
93MP0010678_abnormal_skin_adnexa1.01023756
94MP0002876_abnormal_thyroid_physiology1.00498863
95MP0001299_abnormal_eye_distance/1.00190690
96MP0004142_abnormal_muscle_tone0.98775104
97MP0003632_abnormal_nervous_system0.98499624
98MP0000759_abnormal_skeletal_muscle0.97806946
99MP0005645_abnormal_hypothalamus_physiol0.96745587
100MP0002108_abnormal_muscle_morphology0.94142304
101MP0006072_abnormal_retinal_apoptosis0.93515458
102MP0010630_abnormal_cardiac_muscle0.91533941
103MP0005253_abnormal_eye_physiology0.91350530
104MP0001944_abnormal_pancreas_morphology0.90721108
105MP0000462_abnormal_digestive_system0.89686109
106MP0002736_abnormal_nociception_after0.89600116
107MP0002295_abnormal_pulmonary_circulatio0.88587147
108MP0002127_abnormal_cardiovascular_syste0.87045571
109MP0005388_respiratory_system_phenotype0.86629171
110MP0002133_abnormal_respiratory_system0.86629171
111MP0002896_abnormal_bone_mineralization0.86586431
112MP0002971_abnormal_brown_adipose0.86251114
113MP0002752_abnormal_somatic_nervous0.85972804
114MP0000013_abnormal_adipose_tissue0.83917751
115MP0003045_fibrosis0.83721390
116MP0005248_abnormal_Harderian_gland0.82948907
117MP0005375_adipose_tissue_phenotype0.82090648
118MP0002009_preneoplasia0.81084829
119MP0002090_abnormal_vision0.80889876
120MP0001963_abnormal_hearing_physiology0.80607855
121MP0002909_abnormal_adrenal_gland0.80466955
122MP0002152_abnormal_brain_morphology0.80392816
123MP0004147_increased_porphyrin_level0.80249075
124MP0000750_abnormal_muscle_regeneration0.79645114
125MP0002269_muscular_atrophy0.79025113
126MP0004811_abnormal_neuron_physiology0.78365041
127MP0001501_abnormal_sleep_pattern0.78249925
128MP0000516_abnormal_urinary_system0.77573622
129MP0005367_renal/urinary_system_phenotyp0.77573622
130MP0001661_extended_life_span0.77459846
131MP0000631_abnormal_neuroendocrine_gland0.75958769
132MP0001756_abnormal_urination0.75890094

Predicted human phenotypes

RankGene SetZ-score
1Nemaline bodies (HP:0003798)4.51109167
2Sudden death (HP:0001699)3.97599187
3Muscle hypertrophy of the lower extremities (HP:0008968)3.83854148
4Neurofibrillary tangles (HP:0002185)3.82351668
5Degeneration of the lateral corticospinal tracts (HP:0002314)3.80430608
6Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.80430608
7Exercise-induced myalgia (HP:0003738)3.66986416
8Calf muscle hypertrophy (HP:0008981)3.64054201
9Muscle fiber splitting (HP:0003555)3.61405744
10Focal motor seizures (HP:0011153)3.54840308
11Myokymia (HP:0002411)3.54511371
12Hyporeflexia of lower limbs (HP:0002600)3.37558595
13Termporal pattern (HP:0011008)3.37273021
14Insidious onset (HP:0003587)3.37273021
15Type 1 muscle fiber predominance (HP:0003803)3.33070061
16Atrial fibrillation (HP:0005110)3.28509619
17Abnormality of the calf musculature (HP:0001430)3.16285098
18Abnormality of the corticospinal tract (HP:0002492)3.14658377
19Primary atrial arrhythmia (HP:0001692)3.06641820
20Prolonged QT interval (HP:0001657)3.04697512
21Cerebral inclusion bodies (HP:0100314)2.97375178
22Distal arthrogryposis (HP:0005684)2.90740961
23Action tremor (HP:0002345)2.87630160
24Supraventricular tachycardia (HP:0004755)2.85148592
25Onion bulb formation (HP:0003383)2.84877041
26Supraventricular arrhythmia (HP:0005115)2.82528235
27Supranuclear gaze palsy (HP:0000605)2.82431782
28Difficulty running (HP:0009046)2.82041122
29Syncope (HP:0001279)2.80686694
30Exercise-induced muscle cramps (HP:0003710)2.69398651
31Ankle clonus (HP:0011448)2.68338992
32Foot dorsiflexor weakness (HP:0009027)2.65184972
33Focal seizures (HP:0007359)2.55465596
34Ventricular tachycardia (HP:0004756)2.55117576
35Bundle branch block (HP:0011710)2.53016042
36Pheochromocytoma (HP:0002666)2.52696188
37Myoglobinuria (HP:0002913)2.52067165
38Abnormality of the ischium (HP:0003174)2.51838763
39Dysmetria (HP:0001310)2.51154005
40Atonic seizures (HP:0010819)2.51007532
41Abnormality of the foot musculature (HP:0001436)2.50225545
42Peripheral hypomyelination (HP:0007182)2.44025086
43Hyperglycemia (HP:0003074)2.43032542
44EMG: myopathic abnormalities (HP:0003458)2.42160145
45Ulnar claw (HP:0001178)2.42103279
46Epileptic encephalopathy (HP:0200134)2.40276471
47Round ear (HP:0100830)2.37612179
48Hypoglycemic coma (HP:0001325)2.36886680
49Aplasia involving bones of the extremities (HP:0009825)2.33635497
50Aplasia involving bones of the upper limbs (HP:0009823)2.33635497
51Aplasia of the phalanges of the hand (HP:0009802)2.33635497
52Frequent falls (HP:0002359)2.32758031
53Hyperinsulinemic hypoglycemia (HP:0000825)2.30757542
54Steppage gait (HP:0003376)2.28237514
55Broad-based gait (HP:0002136)2.28164584
56Increased variability in muscle fiber diameter (HP:0003557)2.27437961
57Fetal akinesia sequence (HP:0001989)2.27245108
58Abnormal EKG (HP:0003115)2.26877174
59Intention tremor (HP:0002080)2.25570007
60Large for gestational age (HP:0001520)2.24359144
61Cerebral hemorrhage (HP:0001342)2.24273349
62Spastic gait (HP:0002064)2.22753019
63Sensory axonal neuropathy (HP:0003390)2.18255070
64Rimmed vacuoles (HP:0003805)2.17323479
65Myotonia (HP:0002486)2.17070231
66Insulin-resistant diabetes mellitus (HP:0000831)2.16026374
67Thickened helices (HP:0000391)2.14642807
68Neuroendocrine neoplasm (HP:0100634)2.09343082
69Hyperkalemia (HP:0002153)2.08375922
70Megalencephaly (HP:0001355)2.08233251
71Lower limb muscle weakness (HP:0007340)2.07803232
72Alacrima (HP:0000522)2.07618336
73Postural tremor (HP:0002174)2.07493768
74Ketoacidosis (HP:0001993)2.02658071
75Dysdiadochokinesis (HP:0002075)2.01577430
76Gowers sign (HP:0003391)2.01154742
77Ventricular fibrillation (HP:0001663)1.99583469
78Blue irides (HP:0000635)1.99173639
79Scapular winging (HP:0003691)1.97663656
80Asymmetric septal hypertrophy (HP:0001670)1.97396745
81Hammertoe (HP:0001765)1.97013516
82Broad metatarsal (HP:0001783)1.96269131
83Heart block (HP:0012722)1.95932608
84Ventricular arrhythmia (HP:0004308)1.94375808
85Segmental peripheral demyelination/remyelination (HP:0003481)1.92763819
86Rapidly progressive (HP:0003678)1.92709308
87Epileptiform EEG discharges (HP:0011182)1.92646662
88Scanning speech (HP:0002168)1.91996018
89Lipoatrophy (HP:0100578)1.89233386
90Increased circulating renin level (HP:0000848)1.85836631
91EEG with generalized epileptiform discharges (HP:0011198)1.85371751
92Dilated cardiomyopathy (HP:0001644)1.84786030
93Hypoplastic left heart (HP:0004383)1.84751443
94Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.84253930
95Hyperventilation (HP:0002883)1.83435162
96Macroorchidism (HP:0000053)1.83271483
97Calcaneovalgus deformity (HP:0001848)1.82175841
98Abnormality of skeletal muscle fiber size (HP:0012084)1.82011705
99Rhabdomyolysis (HP:0003201)1.80975926
100Muscle fiber inclusion bodies (HP:0100299)1.80532276
101Urinary urgency (HP:0000012)1.79986379
102Febrile seizures (HP:0002373)1.79265102
103Hyperactive renin-angiotensin system (HP:0000841)1.78477717
104Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.78154363
105Truncal ataxia (HP:0002078)1.77998782
106Hemiparesis (HP:0001269)1.77984739
107Progressive cerebellar ataxia (HP:0002073)1.77278043
108Dysmetric saccades (HP:0000641)1.77219145
109Hypoplastic ischia (HP:0003175)1.76775787
110Hyperaldosteronism (HP:0000859)1.76283283
111Abnormal atrioventricular conduction (HP:0005150)1.75395536
112Anxiety (HP:0000739)1.74865049
113EMG: neuropathic changes (HP:0003445)1.74537161
114Anteriorly placed anus (HP:0001545)1.74191490
115Hypoplasia of the iris (HP:0007676)1.73688697
116Decreased motor nerve conduction velocity (HP:0003431)1.73683808
117Hypsarrhythmia (HP:0002521)1.72609780
118Neck muscle weakness (HP:0000467)1.72255708
119Retinal dysplasia (HP:0007973)1.71708642
120Morphological abnormality of the inner ear (HP:0011390)1.71706171
121Left ventricular hypertrophy (HP:0001712)1.71573914
122Hypokalemic alkalosis (HP:0001949)1.71444967
123Limited hip movement (HP:0008800)1.71164107
124Abnormality of the left ventricular outflow tract (HP:0011103)1.70301187
125Subaortic stenosis (HP:0001682)1.70301187
126Areflexia of lower limbs (HP:0002522)1.70110514
127Gaze-evoked nystagmus (HP:0000640)1.69499849
128Hypothermia (HP:0002045)1.69112777
129Muscle stiffness (HP:0003552)1.68940427
130Right ventricular cardiomyopathy (HP:0011663)1.68471012
131Exotropia (HP:0000577)1.68047832
132Popliteal pterygium (HP:0009756)1.67668065
133Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.67367353
134Absent phalangeal crease (HP:0006109)1.66572375
135Hypoglycemic seizures (HP:0002173)1.66036337
136Atrioventricular block (HP:0001678)1.65982835
137Urinary bladder sphincter dysfunction (HP:0002839)1.65924809
138Generalized tonic-clonic seizures (HP:0002069)1.65586862
139Renal cortical cysts (HP:0000803)1.59969778
140Drooling (HP:0002307)1.58827269
141Poor eye contact (HP:0000817)1.55296402
142Hyperphosphatemia (HP:0002905)1.55273498
143Deformed tarsal bones (HP:0008119)1.53654102
144Increased connective tissue (HP:0009025)1.53443727
145Absent speech (HP:0001344)1.53389297
146Proximal amyotrophy (HP:0007126)1.53074427
147Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.52394262
148Myopathic facies (HP:0002058)1.51648938
149Absence seizures (HP:0002121)1.51223117
150Akinesia (HP:0002304)1.50746193
151Bradycardia (HP:0001662)1.49651719

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE14.93486146
2STK393.53949423
3FRK3.34833905
4PHKG12.82876098
5PHKG22.82876098
6OXSR12.40268897
7LMTK22.34932832
8EPHA42.34715461
9MARK12.27514324
10TNIK1.78209214
11PKN11.78086145
12EPHB11.72276313
13OBSCN1.69020392
14NTRK31.67881242
15CASK1.66028120
16ICK1.62054347
17WNK41.61834665
18TTN1.58661259
19PAK61.57967993
20DMPK1.56693725
21FGFR21.47270035
22ERBB31.45804837
23UHMK11.43095030
24WNK11.40856948
25PRPF4B1.38670677
26PINK11.37825349
27BCR1.36747169
28PRKD31.33541378
29PAK31.33363253
30NTRK11.30240836
31NTRK21.28567562
32CAMK2D1.25976639
33MAP3K41.25495580
34PNCK1.21100049
35SGK4941.19521400
36SGK2231.19521400
37ROCK21.19383791
38CAMK2B1.17416883
39MUSK1.16874611
40EEF2K1.15985627
41CAMK1G1.15823332
42PLK21.12530208
43MARK21.10995846
44MST1R1.10030008
45BMPR1B1.09948650
46MAPKAPK31.05812227
47CAMK2A1.05671376
48PRKCE1.03398330
49PRKD11.03265881
50CDK51.01056565
51STK38L1.00873535
52AKT30.97249982
53TYRO30.97016477
54PIK3CA0.96033910
55NEK60.93329724
56MAPK130.92939578
57PRKAA20.91134941
58FGR0.91073965
59MYLK0.90350704
60CAMKK20.90261653
61BRSK20.89157515
62DDR20.88826609
63MAP4K20.88582568
64DAPK20.88209563
65MAP3K90.87867167
66NEK90.85079957
67GRK10.85060223
68MET0.83589137
69PRKCH0.81547506
70CAMK2G0.80998284
71LATS10.80973054
72MINK10.80363121
73KSR20.78396454
74LIMK10.77925299
75PRKAA10.77874327
76EPHA30.77666742
77CSNK1G20.77326407
78PTK2B0.76056235
79EPHB20.75928172
80CSNK1A1L0.75116205
81MAPKAPK50.71263584
82ROCK10.70654877
83CDK190.69722327
84MAPK150.69250273
85SGK30.68541197
86MAP2K70.68098090
87PDPK10.65181297
88FGFR30.64208548
89YES10.64117757
90GRK70.63902966
91CSNK1G30.63835541
92PDK20.63550320
93CDC42BPA0.63443041
94EIF2AK30.63391451
95PTK20.62435191
96MAP3K120.62366183
97MAPK120.62085836
98FER0.61647992
99BMX0.61222847
100MST40.60604521
101INSRR0.60528702
102TRPM70.58033219
103CSNK1G10.57805558
104WNK30.57608009
105KSR10.56663173
106CAMK10.56566048
107STK240.56205677
108STK380.54445255
109PRKCG0.53370250
110PDK30.53302305
111PDK40.53302305
112SGK10.52872846
113AKT20.52134703
114GRK50.51479050
115MAP2K10.50223846
116CDK140.50074408
117FYN0.49584450
118CAMK1D0.49454167
119STK110.48435145
120MAP3K70.48048876
121PRKACB0.47835962
122SGK20.46269707
123LATS20.46063929
124PRKG10.45716649
125PDGFRA0.45715736
126MAPK100.44311942
127MAP3K20.43599883
128ERBB40.43301586
129PRKCZ0.43151004
130DYRK20.42956311
131DYRK1A0.42726613
132MAP2K40.42725744
133CDK150.42637519

Predicted pathways (KEGG)

RankGene SetZ-score
1Dilated cardiomyopathy_Homo sapiens_hsa054142.12528131
2GABAergic synapse_Homo sapiens_hsa047272.08873403
3Cardiac muscle contraction_Homo sapiens_hsa042602.03606950
4Nicotine addiction_Homo sapiens_hsa050332.00064351
5Maturity onset diabetes of the young_Homo sapiens_hsa049501.98347810
6Morphine addiction_Homo sapiens_hsa050321.98263221
7Circadian entrainment_Homo sapiens_hsa047131.96574973
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.90929237
9Glutamatergic synapse_Homo sapiens_hsa047241.90779264
10Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.81668245
11Axon guidance_Homo sapiens_hsa043601.76978631
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.67670667
13Olfactory transduction_Homo sapiens_hsa047401.67308329
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.66267062
15Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.65115728
16Fatty acid elongation_Homo sapiens_hsa000621.64383949
17Gastric acid secretion_Homo sapiens_hsa049711.62748127
18Salivary secretion_Homo sapiens_hsa049701.60735806
19Renin secretion_Homo sapiens_hsa049241.57689196
20Taste transduction_Homo sapiens_hsa047421.51355180
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.49389577
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.47947617
23Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.46549687
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.44767179
25Synaptic vesicle cycle_Homo sapiens_hsa047211.43297069
26Cholinergic synapse_Homo sapiens_hsa047251.42043924
27Insulin secretion_Homo sapiens_hsa049111.37932197
28Serotonergic synapse_Homo sapiens_hsa047261.36374500
29Long-term depression_Homo sapiens_hsa047301.36271149
30Long-term potentiation_Homo sapiens_hsa047201.36204582
31Vitamin B6 metabolism_Homo sapiens_hsa007501.33243570
32Dopaminergic synapse_Homo sapiens_hsa047281.32396359
33Oxytocin signaling pathway_Homo sapiens_hsa049211.30420135
34Calcium signaling pathway_Homo sapiens_hsa040201.30004647
35Glucagon signaling pathway_Homo sapiens_hsa049221.29808652
36Vascular smooth muscle contraction_Homo sapiens_hsa042701.29607198
37Amphetamine addiction_Homo sapiens_hsa050311.26513651
38Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.25965702
39Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.25138321
40Tight junction_Homo sapiens_hsa045301.24612080
41Gap junction_Homo sapiens_hsa045401.23722701
42Aldosterone synthesis and secretion_Homo sapiens_hsa049251.23510744
43Oxidative phosphorylation_Homo sapiens_hsa001901.22124478
44Arginine biosynthesis_Homo sapiens_hsa002201.21968409
45Cocaine addiction_Homo sapiens_hsa050301.17351383
46cAMP signaling pathway_Homo sapiens_hsa040241.15563482
47Folate biosynthesis_Homo sapiens_hsa007901.13997946
48cGMP-PKG signaling pathway_Homo sapiens_hsa040221.13792932
49Alzheimers disease_Homo sapiens_hsa050101.11059903
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.09894269
51Dorso-ventral axis formation_Homo sapiens_hsa043201.09610383
52beta-Alanine metabolism_Homo sapiens_hsa004101.08801166
53Ether lipid metabolism_Homo sapiens_hsa005651.07826714
54ABC transporters_Homo sapiens_hsa020101.07151709
55Histidine metabolism_Homo sapiens_hsa003401.06697122
56Nitrogen metabolism_Homo sapiens_hsa009101.04616956
57Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.04458128
58Parkinsons disease_Homo sapiens_hsa050121.03063306
59Renal cell carcinoma_Homo sapiens_hsa052111.01868571
60Melanogenesis_Homo sapiens_hsa049160.98010647
61GnRH signaling pathway_Homo sapiens_hsa049120.96996503
62Butanoate metabolism_Homo sapiens_hsa006500.95891457
63Ovarian steroidogenesis_Homo sapiens_hsa049130.95397437
642-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.94904785
65Fatty acid biosynthesis_Homo sapiens_hsa000610.93815492
66Tryptophan metabolism_Homo sapiens_hsa003800.90388593
67ECM-receptor interaction_Homo sapiens_hsa045120.90376077
68Pancreatic secretion_Homo sapiens_hsa049720.89302181
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.88363298
70Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87344466
71Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.86830967
72Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84994380
73Ras signaling pathway_Homo sapiens_hsa040140.84668246
74ErbB signaling pathway_Homo sapiens_hsa040120.83346313
75Fatty acid degradation_Homo sapiens_hsa000710.82728447
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81752596
77Estrogen signaling pathway_Homo sapiens_hsa049150.81329216
78Focal adhesion_Homo sapiens_hsa045100.80150928
79Propanoate metabolism_Homo sapiens_hsa006400.80108997
80AMPK signaling pathway_Homo sapiens_hsa041520.79912306
81Rap1 signaling pathway_Homo sapiens_hsa040150.78544607
82Collecting duct acid secretion_Homo sapiens_hsa049660.77508820
83Steroid biosynthesis_Homo sapiens_hsa001000.77475252
84Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.75903097
85Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.74257203
86Vibrio cholerae infection_Homo sapiens_hsa051100.72768232
87Phototransduction_Homo sapiens_hsa047440.71738846
88Insulin signaling pathway_Homo sapiens_hsa049100.70527862
89Hedgehog signaling pathway_Homo sapiens_hsa043400.70273668
90Phenylalanine metabolism_Homo sapiens_hsa003600.69714791
91Endocytosis_Homo sapiens_hsa041440.68366416
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68229175
93Fatty acid metabolism_Homo sapiens_hsa012120.67688841
94Pyruvate metabolism_Homo sapiens_hsa006200.67350775
95Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.67268068
96Choline metabolism in cancer_Homo sapiens_hsa052310.66038417
97Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65359281
98Type II diabetes mellitus_Homo sapiens_hsa049300.65161778
99Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65003152
100Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64353518
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62334173
102Insulin resistance_Homo sapiens_hsa049310.61107209
103Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60363065
104Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60336727
105Wnt signaling pathway_Homo sapiens_hsa043100.60245296
106Selenocompound metabolism_Homo sapiens_hsa004500.59706876
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.59397126
108MAPK signaling pathway_Homo sapiens_hsa040100.59210645
109Hippo signaling pathway_Homo sapiens_hsa043900.57976546
110Sphingolipid metabolism_Homo sapiens_hsa006000.56552803
111Mineral absorption_Homo sapiens_hsa049780.56174143
112Lysine degradation_Homo sapiens_hsa003100.56033482
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55113895
114Peroxisome_Homo sapiens_hsa041460.55041671
115Huntingtons disease_Homo sapiens_hsa050160.55025924
116Thyroid hormone synthesis_Homo sapiens_hsa049180.54970429
117mTOR signaling pathway_Homo sapiens_hsa041500.52770999
118Regulation of autophagy_Homo sapiens_hsa041400.51343063
119Bile secretion_Homo sapiens_hsa049760.51137422
120Circadian rhythm_Homo sapiens_hsa047100.50736314
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50040839
122PPAR signaling pathway_Homo sapiens_hsa033200.49241509
123Sulfur metabolism_Homo sapiens_hsa009200.48572536
124Protein export_Homo sapiens_hsa030600.48367466
125Basal cell carcinoma_Homo sapiens_hsa052170.47715649
126Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47266087
127Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.46889883
128Adherens junction_Homo sapiens_hsa045200.46279184
129Glioma_Homo sapiens_hsa052140.46200226
130Arginine and proline metabolism_Homo sapiens_hsa003300.44104404
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43260644
132Viral myocarditis_Homo sapiens_hsa054160.42048133

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »