LIMD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous antigen (GO:0019883)4.72647294
2positive regulation of gamma-delta T cell activation (GO:0046645)4.61922576
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.60774541
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.60774541
5histone H3-K36 demethylation (GO:0070544)4.09852227
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.89586335
7mannose metabolic process (GO:0006013)3.80744928
8regulation of gamma-delta T cell differentiation (GO:0045586)3.71595574
9regulation of interleukin-12 biosynthetic process (GO:0045075)3.57184339
10interkinetic nuclear migration (GO:0022027)3.55988742
11regulation of gamma-delta T cell activation (GO:0046643)3.50658467
12histone H3-K9 modification (GO:0061647)3.44599797
13cellular response to ethanol (GO:0071361)3.39794586
14positive regulation of granulocyte differentiation (GO:0030854)3.21761376
15positive regulation of developmental pigmentation (GO:0048087)3.20808854
16histone H3-K9 methylation (GO:0051567)3.19335349
17striated muscle atrophy (GO:0014891)3.17889063
18regulation of histone H3-K27 methylation (GO:0061085)3.16890410
19monoubiquitinated protein deubiquitination (GO:0035520)3.16814043
20surfactant homeostasis (GO:0043129)3.14990419
21nuclear pore complex assembly (GO:0051292)3.14414093
22histone H3-K4 trimethylation (GO:0080182)3.12434699
23positive thymic T cell selection (GO:0045059)3.10206954
24cellular response to zinc ion (GO:0071294)3.05116011
25regulation of B cell differentiation (GO:0045577)3.02960995
26pericardium development (GO:0060039)3.02769600
27positive regulation of B cell differentiation (GO:0045579)3.01301682
28regulation of interferon-beta biosynthetic process (GO:0045357)2.97972611
29glucocorticoid receptor signaling pathway (GO:0042921)2.94354181
30regulation of RNA export from nucleus (GO:0046831)2.93646437
31phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.93562443
32embryonic process involved in female pregnancy (GO:0060136)2.83182821
33JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.81594269
34positive regulation of interferon-alpha production (GO:0032727)2.80261898
35skeletal muscle adaptation (GO:0043501)2.79766691
36neutrophil activation involved in immune response (GO:0002283)2.79711966
37negative regulation of histone methylation (GO:0031061)2.78508516
38negative regulation of myotube differentiation (GO:0010832)2.77941336
39B cell receptor signaling pathway (GO:0050853)2.76862762
40nuclear pore organization (GO:0006999)2.74811401
41regulation of B cell receptor signaling pathway (GO:0050855)2.73681942
42histone lysine methylation (GO:0034968)2.72512435
43peptidyl-lysine dimethylation (GO:0018027)2.71490357
44positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.71483539
45hepatocyte apoptotic process (GO:0097284)2.70000490
46immunoglobulin mediated immune response (GO:0016064)2.68611602
47negative regulation of fatty acid transport (GO:2000192)2.68174925
48chemical homeostasis within a tissue (GO:0048875)2.68003932
49peptidyl-lysine methylation (GO:0018022)2.67305072
50positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.66489590
51response to muramyl dipeptide (GO:0032495)2.66423843
52iron ion import (GO:0097286)2.65954037
53corticosteroid receptor signaling pathway (GO:0031958)2.65279141
54lipid translocation (GO:0034204)2.63542252
55phospholipid translocation (GO:0045332)2.63542252
56NIK/NF-kappaB signaling (GO:0038061)2.63383130
57regulation of interferon-alpha production (GO:0032647)2.63063071
58protein K48-linked deubiquitination (GO:0071108)2.62734931
59pre-miRNA processing (GO:0031054)2.60903060
60cellular response to exogenous dsRNA (GO:0071360)2.57463173
61negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.52429833
62negative regulation of cell killing (GO:0031342)2.52429833
63positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.52347991
64muscle atrophy (GO:0014889)2.51495169
65positive regulation of protein deacetylation (GO:0090312)2.50176001
66histone H3-K4 methylation (GO:0051568)2.49842902
67negative thymic T cell selection (GO:0045060)2.49781993
68positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.47577071
69positive regulation of natural killer cell differentiation (GO:0032825)2.46849959
70natural killer cell mediated cytotoxicity (GO:0042267)2.46741866
71natural killer cell mediated immunity (GO:0002228)2.46741866
72negative T cell selection (GO:0043383)2.46082199
73growth hormone receptor signaling pathway (GO:0060396)2.45361685
74neutrophil activation (GO:0042119)2.45258906
75negative regulation of complement activation (GO:0045916)2.44608174
76regulation of pigment cell differentiation (GO:0050932)2.44225702
77modulation by symbiont of host immune response (GO:0052553)2.44058421
78positive regulation by symbiont of host defense response (GO:0052509)2.44058421
79modulation by symbiont of host defense response (GO:0052031)2.44058421
80modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.44058421
81modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.44058421
82positive regulation by organism of defense response of other organism involved in symbiotic interact2.44058421
83granulocyte activation (GO:0036230)2.42453564
84thymic T cell selection (GO:0045061)2.40599019
85B cell homeostasis (GO:0001782)2.39186738
86insulin-like growth factor receptor signaling pathway (GO:0048009)2.39172424
87CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.38779013
88myeloid dendritic cell activation (GO:0001773)2.38712625
89peptidyl-lysine trimethylation (GO:0018023)2.38432405
90cell-substrate adherens junction assembly (GO:0007045)2.38018594
91focal adhesion assembly (GO:0048041)2.38018594
92positive regulation of histone deacetylation (GO:0031065)2.37574871
93pinocytosis (GO:0006907)2.37273085
94definitive hemopoiesis (GO:0060216)2.36833300
95regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.36778113
96germinal center formation (GO:0002467)2.35698354
97positive regulation of DNA-templated transcription, initiation (GO:2000144)2.34070218
98T cell migration (GO:0072678)2.33467134
99regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.32340015
100regulation of establishment of cell polarity (GO:2000114)2.32068617
101regulation of alpha-beta T cell proliferation (GO:0046640)2.31878514
102negative regulation of protein activation cascade (GO:2000258)2.30021281
103negative regulation of humoral immune response (GO:0002921)2.29836722
104histone lysine demethylation (GO:0070076)2.29178573
105positive regulation of isotype switching (GO:0045830)2.28192128
106regulation of granulocyte differentiation (GO:0030852)2.25904948
107positive regulation of antigen processing and presentation (GO:0002579)2.25882269
108regulation of nucleobase-containing compound transport (GO:0032239)2.25615137
109positive regulation of humoral immune response (GO:0002922)2.25055025
110hydrogen peroxide biosynthetic process (GO:0050665)2.24625587
111positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.24255629
112morphogenesis of an endothelium (GO:0003159)2.23256935
113endothelial tube morphogenesis (GO:0061154)2.23256935
114natural killer cell differentiation (GO:0001779)2.22574615
115mitochondrion distribution (GO:0048311)2.22547357
116N-terminal protein amino acid acetylation (GO:0006474)2.22537806
117regulation of cholesterol storage (GO:0010885)2.21201188
118positive regulation of protein import into nucleus, translocation (GO:0033160)2.21078254
119response to type I interferon (GO:0034340)2.20703705
120lipopolysaccharide-mediated signaling pathway (GO:0031663)2.20094431
121myeloid dendritic cell differentiation (GO:0043011)2.19521740
122positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.19255438
123B cell mediated immunity (GO:0019724)2.18369513
124determination of adult lifespan (GO:0008340)2.18350431
125pore complex assembly (GO:0046931)2.17503250
126myofibril assembly (GO:0030239)2.16404983
127macrophage activation involved in immune response (GO:0002281)2.16336663
128T cell lineage commitment (GO:0002360)2.16256234
129negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.15958211
130negative regulation of translation, ncRNA-mediated (GO:0040033)2.15958211
131regulation of translation, ncRNA-mediated (GO:0045974)2.15958211
132response to peptidoglycan (GO:0032494)2.15833506
133phosphatidylinositol phosphorylation (GO:0046854)2.15675905
134negative regulation of erythrocyte differentiation (GO:0045647)2.15589788
135regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.14015289
136histone demethylation (GO:0016577)2.14003628
137Arp2/3 complex-mediated actin nucleation (GO:0034314)2.12794041
138low-density lipoprotein particle clearance (GO:0034383)2.12413233
139histone methylation (GO:0016571)2.12369949
140fibroblast migration (GO:0010761)2.12194998
141type I interferon signaling pathway (GO:0060337)2.11932293
142cellular response to type I interferon (GO:0071357)2.11932293
143respiratory burst (GO:0045730)2.11830168
144positive regulation of CREB transcription factor activity (GO:0032793)2.11643577
145positive regulation of interferon-beta production (GO:0032728)2.11047246
146vascular endothelial growth factor signaling pathway (GO:0038084)2.10889622
147snRNA transcription (GO:0009301)2.10889086
148I-kappaB phosphorylation (GO:0007252)2.10368877
149regulation of T cell tolerance induction (GO:0002664)2.09549137
150interferon-gamma-mediated signaling pathway (GO:0060333)2.09030301
151regulation of necroptotic process (GO:0060544)2.08733434
152positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.08708791
153leukocyte cell-cell adhesion (GO:0007159)2.07719696
154myeloid cell homeostasis (GO:0002262)2.07397432
155regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.06599521
156JAK-STAT cascade (GO:0007259)2.06568756
157regulation of type I interferon-mediated signaling pathway (GO:0060338)2.06160945
158cellular extravasation (GO:0045123)2.05990166
159positive regulation of interleukin-2 production (GO:0032743)2.05975371
160T cell selection (GO:0045058)2.05588742
161cellular response to growth hormone stimulus (GO:0071378)2.04586793
162regulation of hypersensitivity (GO:0002883)2.04069713
163T cell apoptotic process (GO:0070231)2.03568153
164leukocyte aggregation (GO:0070486)2.03500050
165COPI coating of Golgi vesicle (GO:0048205)2.03191564
166Golgi transport vesicle coating (GO:0048200)2.03191564
167response to laminar fluid shear stress (GO:0034616)2.02593297
168antigen processing and presentation via MHC class Ib (GO:0002475)2.01035544
169positive regulation of interleukin-12 production (GO:0032735)2.00791472
170positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.00636868
171regulation of response to interferon-gamma (GO:0060330)2.00246870
172regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.00102801
173valine metabolic process (GO:0006573)1.99300452
174positive regulation of p38MAPK cascade (GO:1900745)1.99250804
175positive regulation of lipid storage (GO:0010884)1.98330673

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.57794014
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.67660198
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.26384342
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.05247986
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.03789650
6VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human3.00534769
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.97725724
8IRF8_21731497_ChIP-ChIP_J774_Mouse2.96769728
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.70337345
10E2F7_22180533_ChIP-Seq_HELA_Human2.54379221
11IRF8_27001747_Chip-Seq_BMDM_Mouse2.37240490
12MYC_22102868_ChIP-Seq_BL_Human2.36675364
13NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.34899159
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.34005543
15* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.33243965
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.30528780
17RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.22520341
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.17298265
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.16169930
20PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.15732803
21MYB_21317192_ChIP-Seq_ERMYB_Mouse2.08678801
22STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.07793090
23STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.05556416
24VDR_21846776_ChIP-Seq_THP-1_Human2.04554454
25ESR1_20079471_ChIP-ChIP_T-47D_Human2.03746496
26BP1_19119308_ChIP-ChIP_Hs578T_Human2.01996911
27MAF_26560356_Chip-Seq_TH1_Human1.97377956
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97136299
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.95903118
30GATA1_22025678_ChIP-Seq_K562_Human1.92282838
31* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.89763252
32TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.85457399
33STAT4_19710469_ChIP-ChIP_TH1__Mouse1.84694535
34MYB_26560356_Chip-Seq_TH2_Human1.83926475
35NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.83579088
36PPARA_22158963_ChIP-Seq_LIVER_Mouse1.78770857
37RUNX_20019798_ChIP-Seq_JUKART_Human1.75877887
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.75552884
39FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.74381581
40CLOCK_20551151_ChIP-Seq_293T_Human1.72196042
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.70454000
42SMAD_19615063_ChIP-ChIP_OVARY_Human1.70406491
43NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.69901668
44VDR_24763502_ChIP-Seq_THP-1_Human1.68891432
45STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.64415127
46* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.63885731
47FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63413527
48SCL_19346495_ChIP-Seq_HPC-7_Human1.62628568
49GATA1_19941827_ChIP-Seq_MEL_Mouse1.62366332
50MYB_26560356_Chip-Seq_TH1_Human1.62170001
51GATA1_19941826_ChIP-Seq_K562_Human1.61577091
52* TCF7_22412390_ChIP-Seq_EML_Mouse1.61491698
53SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.59990963
54UTX_26944678_Chip-Seq_JUKART_Human1.59423291
55PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.58603325
56RXR_22158963_ChIP-Seq_LIVER_Mouse1.58553946
57GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.56077737
58SPI1_23547873_ChIP-Seq_NB4_Human1.54610516
59PKCTHETA_26484144_Chip-Seq_BREAST_Human1.52387397
60TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51230908
61ELK3_25401928_ChIP-Seq_HUVEC_Human1.49691541
62NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.45659364
63* LXR_22158963_ChIP-Seq_LIVER_Mouse1.44284334
64SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.43805906
65* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.42434875
66TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.42432440
67RUNX1_22412390_ChIP-Seq_EML_Mouse1.42132783
68RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41546431
69* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.41419348
70FOXM1_23109430_ChIP-Seq_U2OS_Human1.39114196
71TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38656665
72* GATA2_19941826_ChIP-Seq_K562_Human1.38586436
73RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.34126777
74ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.31622413
75* FOXA2_19822575_ChIP-Seq_HepG2_Human1.31424249
76FOXO3_23340844_ChIP-Seq_DLD1_Human1.31335515
77CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.31300528
78STAT6_21828071_ChIP-Seq_BEAS2B_Human1.30146432
79* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.26234109
80AHR_22903824_ChIP-Seq_MCF-7_Human1.25422924
81KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24876280
82RUNX1_27514584_Chip-Seq_MCF-7_Human1.24559058
83PU_27001747_Chip-Seq_BMDM_Mouse1.24192838
84GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24160808
85CTNNB1_20460455_ChIP-Seq_HCT116_Human1.21047574
86SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.20930403
87SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.20930403
88ZNF217_24962896_ChIP-Seq_MCF-7_Human1.20424785
89GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20029793
90NOTCH1_21737748_ChIP-Seq_TLL_Human1.19651357
91EGR1_23403033_ChIP-Seq_LIVER_Mouse1.18363105
92* AR_21572438_ChIP-Seq_LNCaP_Human1.17826104
93ESR2_21235772_ChIP-Seq_MCF-7_Human1.15891116
94KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.15571878
95GATA3_27048872_Chip-Seq_THYMUS_Human1.14618397
96KDM2B_26808549_Chip-Seq_JURKAT_Human1.13809559
97KDM2B_26808549_Chip-Seq_DND41_Human1.12996401
98TRIM28_21343339_ChIP-Seq_HEK293_Human1.12519632
99TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.11843310
100RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11421318
101TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.11256168
102FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11041136
103ESR1_21235772_ChIP-Seq_MCF-7_Human1.10938560
104HIF1A_21447827_ChIP-Seq_MCF-7_Human1.10694691
105* SPI1_23127762_ChIP-Seq_K562_Human1.10271995
106GATA2_21666600_ChIP-Seq_HMVEC_Human1.09872884
107* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.07956140
108FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.07827011
109ARNT_22903824_ChIP-Seq_MCF-7_Human1.07714608
110* MAF_26560356_Chip-Seq_TH2_Human1.07253611
111GATA1_22383799_ChIP-Seq_G1ME_Mouse1.06839625
112CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04927424
113* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.03297533
114NCOR1_26117541_ChIP-Seq_K562_Human1.02966902
115FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.02526313
116DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02432996
117KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.02212995
118SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01426532
119CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01388377
120* TBX20_22080862_ChIP-Seq_HEART_Mouse1.01067014
121* TBX20_22328084_ChIP-Seq_HEART_Mouse1.01067014
122SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00376091
123GATA6_25053715_ChIP-Seq_YYC3_Human1.00307248
124EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.99423538
125* VDR_24787735_ChIP-Seq_THP-1_Human0.98565507
126VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.97218929
127CIITA_25753668_ChIP-Seq_RAJI_Human0.96732460
128PPAR_26484153_Chip-Seq_NCI-H1993_Human0.96422401
129MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.95215159
130CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.93842681
131GATA1_19941827_ChIP-Seq_MEL86_Mouse0.93748589
132ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93651674
133SOX2_27498859_Chip-Seq_STOMACH_Mouse0.93614128
134ERG_20887958_ChIP-Seq_HPC-7_Mouse0.92906658
135* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92801525
136P63_26484246_Chip-Seq_KERATINOCYTES_Human0.92268870

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.27296074
2MP0001835_abnormal_antigen_presentation2.94557930
3MP0000685_abnormal_immune_system2.35083383
4MP0003300_gastrointestinal_ulcer2.16497162
5MP0001790_abnormal_immune_system2.15508917
6MP0005387_immune_system_phenotype2.15508917
7MP0003436_decreased_susceptibility_to2.12534568
8MP0001800_abnormal_humoral_immune2.02810638
9MP0005451_abnormal_body_composition2.02573935
10MP0003705_abnormal_hypodermis_morpholog1.97945627
11MP0009785_altered_susceptibility_to1.89161009
12MP0005000_abnormal_immune_tolerance1.87381450
13* MP0002452_abnormal_antigen_presenting1.87156637
14MP0004381_abnormal_hair_follicle1.84275979
15MP0002166_altered_tumor_susceptibility1.81206745
16MP0002138_abnormal_hepatobiliary_system1.77408928
17MP0002148_abnormal_hypersensitivity_rea1.77249160
18MP0003303_peritoneal_inflammation1.74186327
19MP0005025_abnormal_response_to1.69244375
20MP0006054_spinal_hemorrhage1.68980679
21* MP0002419_abnormal_innate_immunity1.67725124
22MP0005671_abnormal_response_to1.65776028
23MP0002723_abnormal_immune_serum1.65140799
24MP0003763_abnormal_thymus_physiology1.64070118
25MP0004782_abnormal_surfactant_physiolog1.63596414
26MP0004947_skin_inflammation1.58595576
27* MP0002420_abnormal_adaptive_immunity1.58396379
28* MP0001819_abnormal_immune_cell1.57746761
29MP0010352_gastrointestinal_tract_polyps1.54648769
30MP0003566_abnormal_cell_adhesion1.54580504
31MP0002254_reproductive_system_inflammat1.53980779
32MP0002006_tumorigenesis1.53978188
33MP0001853_heart_inflammation1.52659898
34MP0008438_abnormal_cutaneous_collagen1.50432450
35MP0002405_respiratory_system_inflammati1.49605691
36MP0004084_abnormal_cardiac_muscle1.49528935
37MP0005310_abnormal_salivary_gland1.48663527
38MP0004510_myositis1.47232663
39MP0010155_abnormal_intestine_physiology1.42460067
40MP0004036_abnormal_muscle_relaxation1.38847226
41MP0006082_CNS_inflammation1.36293496
42MP0001661_extended_life_span1.36162078
43MP0002398_abnormal_bone_marrow1.36091757
44MP0003950_abnormal_plasma_membrane1.33212737
45MP0002877_abnormal_melanocyte_morpholog1.32326644
46MP0001845_abnormal_inflammatory_respons1.30746870
47MP0005076_abnormal_cell_differentiation1.28717156
48* MP0000716_abnormal_immune_system1.28692363
49MP0000371_diluted_coat_color1.27715415
50MP0005409_darkened_coat_color1.26438851
51MP0003890_abnormal_embryonic-extraembry1.26377738
52MP0003453_abnormal_keratinocyte_physiol1.24335130
53MP0004233_abnormal_muscle_weight1.24093380
54MP0000858_altered_metastatic_potential1.22965125
55MP0003828_pulmonary_edema1.22444484
56MP0001873_stomach_inflammation1.21094999
57MP0010234_abnormal_vibrissa_follicle1.18578308
58MP0008961_abnormal_basal_metabolism1.18469335
59MP0009278_abnormal_bone_marrow1.17944224
60MP0005464_abnormal_platelet_physiology1.17305922
61MP0002933_joint_inflammation1.16718773
62MP0002168_other_aberrant_phenotype1.16689692
63MP0003724_increased_susceptibility_to1.16606147
64MP0009333_abnormal_splenocyte_physiolog1.15534205
65MP0000689_abnormal_spleen_morphology1.14997925
66MP0003448_altered_tumor_morphology1.12882155
67MP0001533_abnormal_skeleton_physiology1.12383992
68* MP0002429_abnormal_blood_cell1.11042442
69MP0002722_abnormal_immune_system1.10426214
70MP0003279_aneurysm1.10128809
71MP0004808_abnormal_hematopoietic_stem1.06890574
72MP0001879_abnormal_lymphatic_vessel1.06607738
73MP0006138_congestive_heart_failure1.06266782
74MP0003868_abnormal_feces_composition1.06251686
75MP0010307_abnormal_tumor_latency1.05822282
76MP0000015_abnormal_ear_pigmentation1.05817850
77MP0005023_abnormal_wound_healing1.05415456
78MP0005360_urolithiasis1.04502336
79MP0004185_abnormal_adipocyte_glucose1.03678032
80MP0003191_abnormal_cellular_cholesterol1.03073061
81MP0005058_abnormal_lysosome_morphology1.02187690
82MP0008469_abnormal_protein_level1.02011216
83MP0002060_abnormal_skin_morphology1.00991289
84MP0000767_abnormal_smooth_muscle0.99747358
85MP0001545_abnormal_hematopoietic_system0.98921404
86MP0005397_hematopoietic_system_phenotyp0.98921404
87MP0005171_absent_coat_pigmentation0.98379601
88MP0002396_abnormal_hematopoietic_system0.98140555
89MP0005275_abnormal_skin_tensile0.97529040
90MP0000733_abnormal_muscle_development0.97411479
91MP0009840_abnormal_foam_cell0.96187636
92MP0005085_abnormal_gallbladder_physiolo0.95247565
93MP0009115_abnormal_fat_cell0.94201620
94MP0003984_embryonic_growth_retardation0.94070226
95MP0002086_abnormal_extraembryonic_tissu0.93954798
96MP0010094_abnormal_chromosome_stability0.93378958
97* MP0002998_abnormal_bone_remodeling0.92956784
98MP0003656_abnormal_erythrocyte_physiolo0.92718249
99MP0003252_abnormal_bile_duct0.92266053
100MP0009764_decreased_sensitivity_to0.91308428
101MP0002088_abnormal_embryonic_growth/wei0.90462576
102MP0002139_abnormal_hepatobiliary_system0.88814237
103MP0000703_abnormal_thymus_morphology0.87690395
104MP0002136_abnormal_kidney_physiology0.87536273
105MP0000569_abnormal_digit_pigmentation0.86251426
106MP0009643_abnormal_urine_homeostasis0.85303958
107MP0000609_abnormal_liver_physiology0.83717363
108MP0003091_abnormal_cell_migration0.82696157
109MP0000490_abnormal_crypts_of0.82446699
110MP0000343_altered_response_to0.81449765
111MP0000465_gastrointestinal_hemorrhage0.81031724
112MP0005220_abnormal_exocrine_pancreas0.80986662
113MP0000383_abnormal_hair_follicle0.79970211
114MP0003646_muscle_fatigue0.79899188
115MP0000470_abnormal_stomach_morphology0.79810349
116MP0010630_abnormal_cardiac_muscle0.79474679
117MP0001958_emphysema0.79220809
118MP0005083_abnormal_biliary_tract0.79039887
119MP0001243_abnormal_dermal_layer0.78746396
120MP0009697_abnormal_copulation0.78646082
121MP0002925_abnormal_cardiovascular_devel0.78546486
122MP0005621_abnormal_cell_physiology0.78119570
123MP0004264_abnormal_extraembryonic_tissu0.78110992
124MP0001851_eye_inflammation0.77481771
125MP0003183_abnormal_peptide_metabolism0.77387220
126MP0001672_abnormal_embryogenesis/_devel0.76517560
127MP0005380_embryogenesis_phenotype0.76517560
128MP0000249_abnormal_blood_vessel0.76390014
129MP0005174_abnormal_tail_pigmentation0.76142144
130MP0001216_abnormal_epidermal_layer0.75942745
131MP0002009_preneoplasia0.75839677
132MP0005257_abnormal_intraocular_pressure0.73885523
133MP0004130_abnormal_muscle_cell0.71958573
134MP0005666_abnormal_adipose_tissue0.71288387
135MP0010368_abnormal_lymphatic_system0.70269820
136MP0001666_abnormal_nutrient_absorption0.70197340
137MP0002019_abnormal_tumor_incidence0.70137258
138MP0000598_abnormal_liver_morphology0.69975973
139MP0005390_skeleton_phenotype0.69687103
140MP0010678_abnormal_skin_adnexa0.69413138
141MP0003045_fibrosis0.69206333

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.79195019
2Recurrent abscess formation (HP:0002722)3.28902974
3Autoimmune thrombocytopenia (HP:0001973)3.23427227
4Clumsiness (HP:0002312)3.23206422
5Dysmetric saccades (HP:0000641)3.22712462
6Recurrent bacterial skin infections (HP:0005406)3.18082621
7Recurrent viral infections (HP:0004429)3.04356250
8Cellulitis (HP:0100658)3.01546404
9Agammaglobulinemia (HP:0004432)2.89973122
10Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.83839795
11Spontaneous hematomas (HP:0007420)2.73336248
12Abnormality of T cell number (HP:0011839)2.69750088
13Recurrent gram-negative bacterial infections (HP:0005420)2.66380443
14Hematochezia (HP:0002573)2.65181441
15Increased neuronal autofluorescent lipopigment (HP:0002074)2.62375333
16Myocardial infarction (HP:0001658)2.61996381
17T lymphocytopenia (HP:0005403)2.61869174
18Myositis (HP:0100614)2.60044682
19Chronic otitis media (HP:0000389)2.58108119
20Recurrent bronchitis (HP:0002837)2.57675315
21Recurrent fungal infections (HP:0002841)2.57584103
22Colitis (HP:0002583)2.45047929
23Interstitial pulmonary disease (HP:0006530)2.41954177
24Inflammation of the large intestine (HP:0002037)2.40622920
25Pustule (HP:0200039)2.40419112
26Osteolytic defects of the hand bones (HP:0009699)2.40264684
27Osteolytic defects of the phalanges of the hand (HP:0009771)2.40264684
28Elevated erythrocyte sedimentation rate (HP:0003565)2.38494370
29Mediastinal lymphadenopathy (HP:0100721)2.37955017
30Abnormality of the thoracic spine (HP:0100711)2.37747580
31Long eyelashes (HP:0000527)2.36790773
32Gastrointestinal stroma tumor (HP:0100723)2.36474129
33Osteomyelitis (HP:0002754)2.36302189
34Increased cerebral lipofuscin (HP:0011813)2.34732385
35Periodontitis (HP:0000704)2.33576763
36Abnormal delayed hypersensitivity skin test (HP:0002963)2.33245058
37Gastrointestinal inflammation (HP:0004386)2.32619572
38Genetic anticipation (HP:0003743)2.29471829
39Nasal polyposis (HP:0100582)2.29214311
40Abnormality of the nasal mucosa (HP:0000433)2.27824320
41Vasculitis (HP:0002633)2.25955279
42Prominent nose (HP:0000448)2.24392025
43Prolonged bleeding time (HP:0003010)2.22643723
44Orchitis (HP:0100796)2.21725673
45Meningitis (HP:0001287)2.18141490
46Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.17129553
47Abnormality of the fingertips (HP:0001211)2.16534410
48Right ventricular cardiomyopathy (HP:0011663)2.16273429
49Abnormality of T cells (HP:0002843)2.16156269
50Recurrent skin infections (HP:0001581)2.16021666
51Hypoglycemic coma (HP:0001325)2.15192025
52Verrucae (HP:0200043)2.14814604
53Papilloma (HP:0012740)2.14814604
54Gingivitis (HP:0000230)2.14065983
55Gastrointestinal infarctions (HP:0005244)2.13976444
56Abnormality of macrophages (HP:0004311)2.13102264
57Thoracic kyphosis (HP:0002942)2.11223253
58Emphysema (HP:0002097)2.09733747
59Neonatal hypoglycemia (HP:0001998)2.08484993
60Esophageal varix (HP:0002040)2.07879131
61Arterial thrombosis (HP:0004420)2.06123664
62Thrombocytosis (HP:0001894)2.02579716
63Hyperacusis (HP:0010780)1.98589277
64Sandal gap (HP:0001852)1.97725696
65Acute myeloid leukemia (HP:0004808)1.95994133
66Increased connective tissue (HP:0009025)1.93788491
67Hyperkalemia (HP:0002153)1.93771570
68Broad face (HP:0000283)1.93485090
69Epistaxis (HP:0000421)1.91472325
70Pulmonary infiltrates (HP:0002113)1.91224876
71Aortic aneurysm (HP:0004942)1.90235044
72Skin ulcer (HP:0200042)1.89687245
73Retrobulbar optic neuritis (HP:0100654)1.89288560
74Optic neuritis (HP:0100653)1.89288560
75Centrally nucleated skeletal muscle fibers (HP:0003687)1.88063343
76Ventricular tachycardia (HP:0004756)1.87876417
77Peritonitis (HP:0002586)1.87762031
78Menorrhagia (HP:0000132)1.87669035
79Decreased circulating renin level (HP:0003351)1.87258918
80Abnormality of cells of the lymphoid lineage (HP:0012140)1.86863527
81Autoimmune hemolytic anemia (HP:0001890)1.86830163
82Vacuolated lymphocytes (HP:0001922)1.86268886
83IgM deficiency (HP:0002850)1.86047589
84Acute lymphatic leukemia (HP:0006721)1.84436975
85Abnormality of T cell physiology (HP:0011840)1.84409573
86Abnormality of the columella (HP:0009929)1.84071420
87Lymphopenia (HP:0001888)1.83753950
88Hepatitis (HP:0012115)1.83736889
89Spondylolisthesis (HP:0003302)1.83366044
90Protruding tongue (HP:0010808)1.81974925
91Short chin (HP:0000331)1.81937876
92Hemorrhage of the eye (HP:0011885)1.81404845
93Urticaria (HP:0001025)1.80900594
94Asymmetric septal hypertrophy (HP:0001670)1.80383378
95Gingival bleeding (HP:0000225)1.80263869
96Granulocytopenia (HP:0001913)1.79538038
97Flat acetabular roof (HP:0003180)1.79419319
98Viral hepatitis (HP:0006562)1.77703164
99Dislocated radial head (HP:0003083)1.76755670
100Exercise-induced myalgia (HP:0003738)1.76343442
101Aortic dissection (HP:0002647)1.76333168
102Capillary hemangiomas (HP:0005306)1.75282769
103Leukocytosis (HP:0001974)1.74930900
104Polycythemia (HP:0001901)1.74826504
105Subacute progressive viral hepatitis (HP:0006572)1.74560220
106Narrow palate (HP:0000189)1.73912629
107Chronic mucocutaneous candidiasis (HP:0002728)1.73389348
108Recurrent cutaneous fungal infections (HP:0011370)1.73389348
109Recurrent lower respiratory tract infections (HP:0002783)1.72571691
110Subaortic stenosis (HP:0001682)1.70346754
111Abnormality of the left ventricular outflow tract (HP:0011103)1.70346754
112Chronic diarrhea (HP:0002028)1.69784002
113Rectal prolapse (HP:0002035)1.69232649
114Thick nail (HP:0001805)1.68829211
115Sepsis (HP:0100806)1.68770231
116Increased IgE level (HP:0003212)1.68728555
117Truncal obesity (HP:0001956)1.68697863
118Thin bony cortex (HP:0002753)1.68602128
119Eosinophilia (HP:0001880)1.68194376
120Fair hair (HP:0002286)1.67742769
121Bicuspid aortic valve (HP:0001647)1.67012205
122Cerebral aneurysm (HP:0004944)1.66989555
123Recurrent pneumonia (HP:0006532)1.66827099
124Persistence of primary teeth (HP:0006335)1.66355344
125Abnormality of monocarboxylic acid metabolism (HP:0010996)1.66145515
126Mucosal telangiectasiae (HP:0100579)1.65864040
127Protrusio acetabuli (HP:0003179)1.65693387
128Petechiae (HP:0000967)1.65002684
129Chest pain (HP:0100749)1.64604971
130IgA deficiency (HP:0002720)1.64392264
131Lip pit (HP:0100267)1.64288537
132Onion bulb formation (HP:0003383)1.64076580
133Poikiloderma (HP:0001029)1.63960928
134Type 1 muscle fiber predominance (HP:0003803)1.63578170
135Recurrent sinusitis (HP:0011108)1.63488616
136Aneurysm (HP:0002617)1.63227397
137Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.63213705
138Ulnar bowing (HP:0003031)1.62886883
139Mitral stenosis (HP:0001718)1.62665194
140Panhypogammaglobulinemia (HP:0003139)1.60694716
141Restrictive lung disease (HP:0002091)1.60664304
142Heterotopia (HP:0002282)1.59035225
143Abnormal platelet volume (HP:0011876)1.58636015
144Spinal cord lesions (HP:0100561)1.57273561
145Syringomyelia (HP:0003396)1.57273561
146Generalized hypopigmentation of hair (HP:0011358)1.56935238
147Micronodular cirrhosis (HP:0001413)1.56934305
148Vertebral arch anomaly (HP:0008438)1.56929446
149Renovascular hypertension (HP:0100817)1.55920129
150Sparse lateral eyebrow (HP:0005338)1.55909905
151Increased mean platelet volume (HP:0011877)1.54485023
152Abnormality of the intrinsic pathway (HP:0010989)1.54213198
153Submucous cleft hard palate (HP:0000176)1.52352988
154Ureteral obstruction (HP:0006000)1.52063548
155Hyporeflexia of lower limbs (HP:0002600)1.51388468
156Germ cell neoplasia (HP:0100728)1.50944254
157Basal cell carcinoma (HP:0002671)1.50772239
158Abnormality of the radial head (HP:0003995)1.49384869

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K12.98062725
2TRIB32.92748960
3MAP3K142.77709401
4PRPF4B2.59574232
5MAP3K102.47673734
6ERN12.44781211
7PKN22.25684762
8ICK2.23715646
9TTN2.17324474
10JAK32.13638841
11TBK12.05417401
12TYK22.04882075
13STK101.80280423
14LRRK21.78503894
15FGFR41.71453972
16NEK91.68958183
17MAP2K31.61432872
18SIK11.57020708
19CAMK1D1.57005735
20IKBKB1.56805172
21IRAK31.53458907
22JAK11.52333085
23TGFBR21.52026730
24CDC42BPA1.51439061
25AKT31.50294696
26EPHA31.50219864
27PTK61.49680357
28FLT31.44421981
29NME21.44153661
30IKBKE1.42383430
31CHUK1.40990877
32BLK1.40814329
33FGFR31.40261157
34SMG11.35974918
35EEF2K1.35879731
36BTK1.34083547
37RPS6KA41.31209833
38ZAP701.31007535
39BRD41.29951667
40CSK1.25435494
41EPHB11.25310634
42KIT1.23978087
43TAOK31.22624149
44STK41.19457442
45IRAK41.19101314
46ITK1.14366197
47MAP3K131.14040474
48MST41.13829164
49CSF1R1.13734132
50NLK1.13633917
51MAP3K31.11632694
52MST1R1.09790077
53PIM11.05334175
54CAMK1G1.02332579
55STK30.97793135
56ACVR1B0.96789686
57TRPM70.94609884
58MARK30.93147195
59PDPK10.93095845
60TEC0.92233186
61TXK0.92175741
62LATS10.91052910
63STK240.89939382
64TNK20.89237489
65PDGFRA0.88413385
66MARK20.88334130
67SGK20.86646286
68SYK0.85668855
69GRK60.84711022
70WNK10.83670252
71PIK3CG0.82820231
72PDK10.82116672
73DMPK0.81373587
74JAK20.81247125
75SGK30.81099028
76INSRR0.77504492
77PBK0.76247577
78PRKD20.74991220
79RIPK10.74900199
80MAPKAPK30.74585557
81MAPK120.74495719
82LCK0.74028380
83KDR0.72323399
84NUAK10.72121348
85BMX0.71345412
86TGFBR10.71230339
87HCK0.70768129
88CDK60.70684498
89RET0.69711362
90CLK10.69676078
91CDK40.68329575
92MAP3K70.67783428
93FRK0.67747134
94CDK120.66694584
95SCYL20.66023539
96LYN0.64384802
97MAP3K80.62657126
98CDK90.62286917
99PRKCQ0.61702518
100RIPK40.61525695
101PDGFRB0.61448953
102MAPK70.60470656
103HIPK20.60046441
104MAP2K20.59581125
105RPS6KA60.59248708
106DYRK1B0.59068856
107CDK80.56817174
108STK380.56507707
109ILK0.56182088
110RPS6KA20.56049849
111STK38L0.54421933
112MELK0.52876975
113FES0.52702673
114RPS6KB20.50841980
115PRKAA10.50493821
116RPS6KC10.49730817
117RPS6KL10.49730817
118OBSCN0.49614649
119MAP3K10.49327529
120BCKDK0.49148841
121BMPR1B0.48407864
122MAPKAPK20.48179923
123YES10.47786473
124SIK20.47450893
125PASK0.46546735
126TLK10.45428858
127TIE10.45298218
128PIM20.45166525
129KSR20.43095097
130ABL10.42289855
131IRAK10.41795105
132PRKAA20.39997761
133MAPK110.38944362
134NEK20.38602047
135MTOR0.38246117

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.55008417
2Leishmaniasis_Homo sapiens_hsa051402.41364687
3Primary immunodeficiency_Homo sapiens_hsa053402.33433872
4B cell receptor signaling pathway_Homo sapiens_hsa046622.15188937
5Osteoclast differentiation_Homo sapiens_hsa043801.88823847
6Antigen processing and presentation_Homo sapiens_hsa046121.85093364
7Toll-like receptor signaling pathway_Homo sapiens_hsa046201.81915550
8Legionellosis_Homo sapiens_hsa051341.78177214
9Measles_Homo sapiens_hsa051621.74618602
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.68902639
11Toxoplasmosis_Homo sapiens_hsa051451.67386215
12NOD-like receptor signaling pathway_Homo sapiens_hsa046211.61216806
13Intestinal immune network for IgA production_Homo sapiens_hsa046721.60064525
14Graft-versus-host disease_Homo sapiens_hsa053321.58762229
15Hematopoietic cell lineage_Homo sapiens_hsa046401.50337972
16Viral myocarditis_Homo sapiens_hsa054161.50039471
17Small cell lung cancer_Homo sapiens_hsa052221.44555098
18TNF signaling pathway_Homo sapiens_hsa046681.40772930
19Malaria_Homo sapiens_hsa051441.40146508
20Chronic myeloid leukemia_Homo sapiens_hsa052201.39885032
21Leukocyte transendothelial migration_Homo sapiens_hsa046701.38085448
22Staphylococcus aureus infection_Homo sapiens_hsa051501.37650490
23Herpes simplex infection_Homo sapiens_hsa051681.35581406
24Apoptosis_Homo sapiens_hsa042101.34586914
25RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.33146904
26Jak-STAT signaling pathway_Homo sapiens_hsa046301.27580019
27Autoimmune thyroid disease_Homo sapiens_hsa053201.25731303
28Pertussis_Homo sapiens_hsa051331.24056262
29Influenza A_Homo sapiens_hsa051641.23858626
30Tuberculosis_Homo sapiens_hsa051521.17596652
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.16040864
32Endometrial cancer_Homo sapiens_hsa052131.13914789
33Caffeine metabolism_Homo sapiens_hsa002321.13526034
34Acute myeloid leukemia_Homo sapiens_hsa052211.12656713
35Insulin resistance_Homo sapiens_hsa049311.12506229
36T cell receptor signaling pathway_Homo sapiens_hsa046601.12409342
37AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11493084
38Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10798059
39Allograft rejection_Homo sapiens_hsa053301.09338989
40Fatty acid degradation_Homo sapiens_hsa000711.05581374
41Hepatitis B_Homo sapiens_hsa051611.04324440
42Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.01749738
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.99906989
44mTOR signaling pathway_Homo sapiens_hsa041500.99579211
45Selenocompound metabolism_Homo sapiens_hsa004500.99387804
46Renal cell carcinoma_Homo sapiens_hsa052110.99163492
47Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.98796406
48Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.97655540
49Pancreatic cancer_Homo sapiens_hsa052120.97271976
50Shigellosis_Homo sapiens_hsa051310.95874774
51Choline metabolism in cancer_Homo sapiens_hsa052310.95325135
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95017899
53Adipocytokine signaling pathway_Homo sapiens_hsa049200.93610954
54VEGF signaling pathway_Homo sapiens_hsa043700.93224692
55Glycosaminoglycan degradation_Homo sapiens_hsa005310.92705363
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.88510688
57Adherens junction_Homo sapiens_hsa045200.88429210
58Viral carcinogenesis_Homo sapiens_hsa052030.88270448
59Dorso-ventral axis formation_Homo sapiens_hsa043200.88216620
60Lysine degradation_Homo sapiens_hsa003100.88080049
61Focal adhesion_Homo sapiens_hsa045100.86867270
62Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.84678762
63Colorectal cancer_Homo sapiens_hsa052100.84362524
64Salmonella infection_Homo sapiens_hsa051320.83484695
65Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.82387107
66MicroRNAs in cancer_Homo sapiens_hsa052060.82307430
67Inositol phosphate metabolism_Homo sapiens_hsa005620.82223340
68HTLV-I infection_Homo sapiens_hsa051660.80685828
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.80248941
70Proteoglycans in cancer_Homo sapiens_hsa052050.80035190
71Other glycan degradation_Homo sapiens_hsa005110.79710215
72Hepatitis C_Homo sapiens_hsa051600.79584740
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.79410851
74Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.78729991
75Lysosome_Homo sapiens_hsa041420.78497350
76Thyroid hormone signaling pathway_Homo sapiens_hsa049190.78076157
77Platelet activation_Homo sapiens_hsa046110.77890300
78ECM-receptor interaction_Homo sapiens_hsa045120.77760085
79Chemokine signaling pathway_Homo sapiens_hsa040620.77579914
80Amoebiasis_Homo sapiens_hsa051460.77302226
81alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.77022098
82p53 signaling pathway_Homo sapiens_hsa041150.76250559
83Complement and coagulation cascades_Homo sapiens_hsa046100.75497428
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.74510930
85Maturity onset diabetes of the young_Homo sapiens_hsa049500.73742160
86PPAR signaling pathway_Homo sapiens_hsa033200.73048260
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.72691550
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72107674
89Systemic lupus erythematosus_Homo sapiens_hsa053220.71059978
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.70708430
91Prolactin signaling pathway_Homo sapiens_hsa049170.70427549
92Tryptophan metabolism_Homo sapiens_hsa003800.70236444
93Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69487454
94Glioma_Homo sapiens_hsa052140.68772040
95ErbB signaling pathway_Homo sapiens_hsa040120.68137177
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66063647
97Insulin signaling pathway_Homo sapiens_hsa049100.65054742
98Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62829997
99Steroid hormone biosynthesis_Homo sapiens_hsa001400.62663404
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61860748
101Thyroid cancer_Homo sapiens_hsa052160.61619487
102Prostate cancer_Homo sapiens_hsa052150.60768139
103Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60547768
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59020955
105Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58588989
106Notch signaling pathway_Homo sapiens_hsa043300.57844577
107Primary bile acid biosynthesis_Homo sapiens_hsa001200.57480926
108FoxO signaling pathway_Homo sapiens_hsa040680.57079323
109Epstein-Barr virus infection_Homo sapiens_hsa051690.57020079
110Starch and sucrose metabolism_Homo sapiens_hsa005000.55524971
111Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.55391678
112Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54892960
113GnRH signaling pathway_Homo sapiens_hsa049120.54819069
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.53262443
115Linoleic acid metabolism_Homo sapiens_hsa005910.52387812
116Type II diabetes mellitus_Homo sapiens_hsa049300.51445562
117Bile secretion_Homo sapiens_hsa049760.51010613
118Propanoate metabolism_Homo sapiens_hsa006400.50606755
119Asthma_Homo sapiens_hsa053100.50597954
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50022738
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.49753379
122Non-small cell lung cancer_Homo sapiens_hsa052230.49030978
123Estrogen signaling pathway_Homo sapiens_hsa049150.48679079
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.48086781
125Glycerolipid metabolism_Homo sapiens_hsa005610.46482496
126Fat digestion and absorption_Homo sapiens_hsa049750.45303238
127ABC transporters_Homo sapiens_hsa020100.43606795
128Protein digestion and absorption_Homo sapiens_hsa049740.43412721
129HIF-1 signaling pathway_Homo sapiens_hsa040660.43112576
130Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.42838550
131Pentose phosphate pathway_Homo sapiens_hsa000300.41916815
132Bladder cancer_Homo sapiens_hsa052190.41834791
133Neurotrophin signaling pathway_Homo sapiens_hsa047220.41096479
134Sulfur metabolism_Homo sapiens_hsa009200.40846386
135Fatty acid metabolism_Homo sapiens_hsa012120.39850221
136Sulfur relay system_Homo sapiens_hsa041220.39348597

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