LIN7B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.93024652
2synaptic vesicle exocytosis (GO:0016079)5.70116290
3vocalization behavior (GO:0071625)5.36576026
4nucleotide transmembrane transport (GO:1901679)5.29412923
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.25526409
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.24839220
7nucleoside transmembrane transport (GO:1901642)5.20284043
8adenine nucleotide transport (GO:0051503)5.13715510
9glutamate secretion (GO:0014047)5.13134969
10purine ribonucleotide transport (GO:0015868)5.09457666
11protein localization to synapse (GO:0035418)5.08616207
12heme transport (GO:0015886)5.03192697
13regulation of glutamate receptor signaling pathway (GO:1900449)4.88442764
14neuron cell-cell adhesion (GO:0007158)4.87427812
15neuronal action potential propagation (GO:0019227)4.87110249
16synaptic vesicle maturation (GO:0016188)4.86987848
17synaptic vesicle docking involved in exocytosis (GO:0016081)4.86899370
18regulation of synaptic vesicle exocytosis (GO:2000300)4.83038229
19locomotory exploration behavior (GO:0035641)4.79688324
20mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.78099542
21ionotropic glutamate receptor signaling pathway (GO:0035235)4.73880125
22organic cation transport (GO:0015695)4.71250445
23regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.70504182
24positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.67774012
25iron coordination entity transport (GO:1901678)4.48451457
26glutamate receptor signaling pathway (GO:0007215)4.41868594
27neuron-neuron synaptic transmission (GO:0007270)4.35004867
28regulation of synaptic vesicle transport (GO:1902803)4.34957374
29regulation of long-term neuronal synaptic plasticity (GO:0048169)4.29876345
30energy coupled proton transport, down electrochemical gradient (GO:0015985)4.27478826
31ATP synthesis coupled proton transport (GO:0015986)4.27478826
32synaptic transmission, glutamatergic (GO:0035249)4.21156472
33exploration behavior (GO:0035640)4.20509422
34regulation of neuronal synaptic plasticity (GO:0048168)4.16549096
35cofactor transport (GO:0051181)4.13816426
36regulation of phospholipid biosynthetic process (GO:0071071)4.11032858
37neurotransmitter-gated ion channel clustering (GO:0072578)4.10431451
38* neurotransmitter secretion (GO:0007269)4.09261046
39chaperone-mediated protein transport (GO:0072321)4.06122180
40phosphatidylglycerol acyl-chain remodeling (GO:0036148)4.05076083
41negative regulation of synaptic transmission, GABAergic (GO:0032229)4.04033342
42gamma-aminobutyric acid signaling pathway (GO:0007214)4.00874444
43regulation of excitatory postsynaptic membrane potential (GO:0060079)3.97215527
44purine nucleotide transport (GO:0015865)3.96437170
45presynaptic membrane assembly (GO:0097105)3.94117532
46regulation of glutamate secretion (GO:0014048)3.91594025
47pyrimidine nucleobase catabolic process (GO:0006208)3.91539746
48long-term synaptic potentiation (GO:0060291)3.90101431
49behavioral response to nicotine (GO:0035095)3.89735366
50regulation of isotype switching to IgG isotypes (GO:0048302)3.87970619
51glycerophospholipid catabolic process (GO:0046475)3.87097093
52negative regulation of type 2 immune response (GO:0002829)3.87036829
53neuron recognition (GO:0008038)3.85582225
54protein K6-linked ubiquitination (GO:0085020)3.82390641
55regulation of postsynaptic membrane potential (GO:0060078)3.81167908
56negative regulation of telomerase activity (GO:0051974)3.78816521
57positive regulation of synapse maturation (GO:0090129)3.77132959
58negative regulation of telomere maintenance (GO:0032205)3.74086075
59synapsis (GO:0007129)3.73779748
60phosphatidylcholine acyl-chain remodeling (GO:0036151)3.72764495
61regulation of synaptic plasticity (GO:0048167)3.72342751
62positive regulation of neurotransmitter secretion (GO:0001956)3.70645368
63presynaptic membrane organization (GO:0097090)3.69516278
64positive regulation of membrane potential (GO:0045838)3.68937203
65long-term memory (GO:0007616)3.63344803
66behavioral response to cocaine (GO:0048148)3.63259584
67synaptic vesicle endocytosis (GO:0048488)3.61983444
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.54780156
69postsynaptic membrane organization (GO:0001941)3.53987905
70regulation of vesicle fusion (GO:0031338)3.53249025
71response to histamine (GO:0034776)3.52619507
72regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49479465
73regulation of dendritic spine morphogenesis (GO:0061001)3.47488390
74positive regulation of neurotransmitter transport (GO:0051590)3.46345537
75regulation of synapse structural plasticity (GO:0051823)3.45978517
76male meiosis I (GO:0007141)3.45835802
77regulation of feeding behavior (GO:0060259)3.42272799
78behavioral defense response (GO:0002209)3.41330284
79behavioral fear response (GO:0001662)3.41330284
80protein neddylation (GO:0045116)3.40209876
81establishment of nucleus localization (GO:0040023)3.39701623
82* neurotransmitter transport (GO:0006836)3.39056022
83negative regulation of amino acid transport (GO:0051956)3.36170692
84fear response (GO:0042596)3.33315125
85regulation of neurotransmitter secretion (GO:0046928)3.32748772
86ATP hydrolysis coupled proton transport (GO:0015991)3.32626661
87energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.32626661
88G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.32577502
89regulation of synaptic transmission, glutamatergic (GO:0051966)3.32435579
90axonal fasciculation (GO:0007413)3.32057880
91nucleoside transport (GO:0015858)3.31582685
92nucleobase catabolic process (GO:0046113)3.29920867
93synaptic transmission, dopaminergic (GO:0001963)3.27771820
94transmission of nerve impulse (GO:0019226)3.26804143
95proline transport (GO:0015824)3.26611752
96G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.25748695
97piRNA metabolic process (GO:0034587)3.24001282
98dendritic spine morphogenesis (GO:0060997)3.22074584
99serotonin metabolic process (GO:0042428)3.19205197
100telomere maintenance via telomerase (GO:0007004)3.19085525
101folic acid transport (GO:0015884)3.19054357
102membrane depolarization (GO:0051899)3.17381824
103negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.17216841
104negative regulation of dendrite morphogenesis (GO:0050774)3.16816881
105* regulation of neurotransmitter levels (GO:0001505)3.16617545
106gamma-aminobutyric acid transport (GO:0015812)3.15831745
107activation of protein kinase A activity (GO:0034199)3.14599983
108detection of calcium ion (GO:0005513)3.14400293
109startle response (GO:0001964)3.13040575
110regulation of dendritic spine development (GO:0060998)3.11948487
111transferrin transport (GO:0033572)3.10214407
112layer formation in cerebral cortex (GO:0021819)3.08420129
113learning (GO:0007612)3.08094768
114neuromuscular process controlling posture (GO:0050884)3.07991149
115synaptic transmission (GO:0007268)3.05953152
116cellular potassium ion homeostasis (GO:0030007)3.05659090
117regulation of female receptivity (GO:0045924)3.04845003
118regulation of neurotransmitter transport (GO:0051588)3.04504882
119cerebellar Purkinje cell differentiation (GO:0021702)3.04226732
120regulation of voltage-gated calcium channel activity (GO:1901385)3.02660689
121long term synaptic depression (GO:0060292)3.02597654
122regulation of synaptic transmission (GO:0050804)3.02396106
123positive regulation of synaptic transmission (GO:0050806)3.01925769
124regulation of telomerase activity (GO:0051972)3.01140503
125innervation (GO:0060384)3.00917304
126positive regulation of T-helper 1 type immune response (GO:0002827)3.00463188
127female mating behavior (GO:0060180)3.00154830
128response to pheromone (GO:0019236)2.99715272
129regulation of neurotransmitter uptake (GO:0051580)2.98596947
130positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.97746200
131establishment of synaptic vesicle localization (GO:0097480)2.96519956
132synaptic vesicle transport (GO:0048489)2.96519956
133regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.96503830
134regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.96503830
135phosphatidylinositol acyl-chain remodeling (GO:0036149)2.96422346
136protein polyglutamylation (GO:0018095)2.95764056
137positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.94922421
138regulation of synapse maturation (GO:0090128)2.94877739
139membrane hyperpolarization (GO:0060081)2.94156707
140inositol phosphate catabolic process (GO:0071545)2.93969793
141negative regulation of dendrite development (GO:2000171)2.93646087
142protein complex biogenesis (GO:0070271)2.92236001
143regulation of protein kinase A signaling (GO:0010738)2.91817183
144membrane depolarization during action potential (GO:0086010)2.91159994
145negative regulation of multicellular organism growth (GO:0040015)2.81540267
146cell migration in hindbrain (GO:0021535)2.80231708
147ATP biosynthetic process (GO:0006754)2.78846518
148cornea development in camera-type eye (GO:0061303)2.74823715
149protein localization to cilium (GO:0061512)2.74566223
150regulation of type B pancreatic cell apoptotic process (GO:2000674)2.70159870
151retinal cone cell development (GO:0046549)2.69087634
152neuron remodeling (GO:0016322)2.67777233
153mitochondrial respiratory chain complex I assembly (GO:0032981)2.66726202
154NADH dehydrogenase complex assembly (GO:0010257)2.66726202
155mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.66726202
156nucleotide transport (GO:0006862)2.66478183
157brain morphogenesis (GO:0048854)2.66092189
158axoneme assembly (GO:0035082)2.64091365
159regulation of cilium movement (GO:0003352)2.62905908
160electron transport chain (GO:0022900)2.62847861
161regulation of microtubule-based movement (GO:0060632)2.62228410
162surfactant homeostasis (GO:0043129)2.61807794
163parturition (GO:0007567)2.60753653
164mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.59104452
165respiratory electron transport chain (GO:0022904)2.58838472
166phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.57956835
167positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.56233957
168metallo-sulfur cluster assembly (GO:0031163)2.56166492
169iron-sulfur cluster assembly (GO:0016226)2.56166492
170cellular ketone body metabolic process (GO:0046950)2.53539996
171inositol phosphate dephosphorylation (GO:0046855)2.53251297
172phosphorylated carbohydrate dephosphorylation (GO:0046838)2.53251297
173mitochondrial respiratory chain complex assembly (GO:0033108)2.51369939
174regulation of action potential (GO:0098900)2.50928825
175DNA methylation involved in gamete generation (GO:0043046)2.50386237
176meiosis I (GO:0007127)2.48958793
177collecting duct development (GO:0072044)2.46916728
178striatum development (GO:0021756)2.46072664
179neuronal action potential (GO:0019228)2.44898316
180detection of light stimulus involved in visual perception (GO:0050908)2.43414748
181detection of light stimulus involved in sensory perception (GO:0050962)2.43414748
182purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.41688924
183positive regulation of meiosis (GO:0045836)2.41283417
184protein deneddylation (GO:0000338)2.41162039
185nonmotile primary cilium assembly (GO:0035058)2.40608755
186polarized epithelial cell differentiation (GO:0030859)2.39975709

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.26479700
2GBX2_23144817_ChIP-Seq_PC3_Human4.21541355
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.89667299
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.34537588
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.22661950
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.18456028
7REST_21632747_ChIP-Seq_MESCs_Mouse2.83907285
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.82968538
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.80914226
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74331940
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.71042317
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.71042317
13RARB_27405468_Chip-Seq_BRAIN_Mouse2.63447012
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.60316256
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59394817
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.58368145
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.53740815
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.52490997
19TAF15_26573619_Chip-Seq_HEK293_Human2.39830087
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.34824809
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.32865650
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.25269110
23NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.20277768
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.18784436
25CTBP2_25329375_ChIP-Seq_LNCAP_Human2.16642221
26EZH2_27294783_Chip-Seq_ESCs_Mouse2.16567378
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.15542009
28CTBP1_25329375_ChIP-Seq_LNCAP_Human2.14244685
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.13867339
30HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.11530254
31DROSHA_22980978_ChIP-Seq_HELA_Human2.08580428
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.91325943
33ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89095737
34AR_21572438_ChIP-Seq_LNCaP_Human1.80407974
35SMAD4_21799915_ChIP-Seq_A2780_Human1.78945273
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75216341
37EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.73342075
38MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.71101807
39P300_19829295_ChIP-Seq_ESCs_Human1.67236668
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.63568128
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.62259511
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.62128839
43TP53_22573176_ChIP-Seq_HFKS_Human1.62011337
44GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.53357761
45GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52617998
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.50477300
47* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.50048441
48ZNF274_21170338_ChIP-Seq_K562_Hela1.48203765
49FUS_26573619_Chip-Seq_HEK293_Human1.47600395
50ETV2_25802403_ChIP-Seq_MESCs_Mouse1.47560282
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.47491617
52VDR_22108803_ChIP-Seq_LS180_Human1.46488895
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.45893852
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.42027519
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40755957
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.38319401
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38230575
58GATA3_21878914_ChIP-Seq_MCF-7_Human1.37990504
59POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37238719
60NR3C1_23031785_ChIP-Seq_PC12_Mouse1.35822037
61AR_25329375_ChIP-Seq_VCAP_Human1.35096583
62CBX2_27304074_Chip-Seq_ESCs_Mouse1.32021782
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.29068120
64EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27731606
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25218830
66CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.23958180
67RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23591454
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.23515018
69NCOR_22424771_ChIP-Seq_293T_Human1.22856766
70TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22130175
71PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22041226
72RNF2_27304074_Chip-Seq_NSC_Mouse1.21584503
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20605503
74TAF2_19829295_ChIP-Seq_ESCs_Human1.20209014
75GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20001301
76RING1B_27294783_Chip-Seq_ESCs_Mouse1.19430125
77RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.18446247
78CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.18125173
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17510591
80FOXA1_25329375_ChIP-Seq_VCAP_Human1.17321758
81FOXA1_27270436_Chip-Seq_PROSTATE_Human1.17321758
82STAT3_23295773_ChIP-Seq_U87_Human1.17302844
83EWS_26573619_Chip-Seq_HEK293_Human1.16499638
84SMAD4_21741376_ChIP-Seq_EPCs_Human1.15976576
85GABP_17652178_ChIP-ChIP_JURKAT_Human1.15201023
86PRDM14_20953172_ChIP-Seq_ESCs_Human1.14982510
87IGF1R_20145208_ChIP-Seq_DFB_Human1.14195664
88ERA_21632823_ChIP-Seq_H3396_Human1.14066599
89KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.12911421
90JUN_21703547_ChIP-Seq_K562_Human1.11125088
91EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.09136801
92AR_20517297_ChIP-Seq_VCAP_Human1.08616457
93DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08143559
94* OCT4_20526341_ChIP-Seq_ESCs_Human1.08125886
95TCF4_23295773_ChIP-Seq_U87_Human1.06851181
96FOXH1_21741376_ChIP-Seq_EPCs_Human1.06753072
97AR_19668381_ChIP-Seq_PC3_Human1.06595341
98PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05766467
99NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.04935311
100JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.04719398
101RUNX2_22187159_ChIP-Seq_PCA_Human1.04355434
102MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03633573
103P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03388063
104PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03111626
105MYC_19829295_ChIP-Seq_ESCs_Human1.02373405
106ARNT_22903824_ChIP-Seq_MCF-7_Human1.02243136
107SOX2_19829295_ChIP-Seq_ESCs_Human1.02222309
108NANOG_19829295_ChIP-Seq_ESCs_Human1.02222309
109IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01503099
110CBP_20019798_ChIP-Seq_JUKART_Human1.01503099
111MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00884117
112AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99909837
113KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99001797
114BCAT_22108803_ChIP-Seq_LS180_Human0.98840981
115AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98613150
116CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97965818
117ER_23166858_ChIP-Seq_MCF-7_Human0.97877888
118SMAD_19615063_ChIP-ChIP_OVARY_Human0.97663632
119ETS1_20019798_ChIP-Seq_JURKAT_Human0.97223222
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96680990
121NANOG_18555785_Chip-Seq_ESCs_Mouse0.96640725
122FOXH1_21741376_ChIP-Seq_ESCs_Human0.96264611
123TP53_18474530_ChIP-ChIP_U2OS_Human0.96081359
124AHR_22903824_ChIP-Seq_MCF-7_Human0.96072154
125PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94978831
126SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.94719343
127CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94692269
128TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93838932
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.93838932
130TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93341852
131EST1_17652178_ChIP-ChIP_JURKAT_Human0.93301300
132RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.92898361
133YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92837479
134ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.92764315
135TP53_16413492_ChIP-PET_HCT116_Human0.92348638
136RING1B_27294783_Chip-Seq_NPCs_Mouse0.91661812
137SMAD3_21741376_ChIP-Seq_ESCs_Human0.90588268
138WT1_25993318_ChIP-Seq_PODOCYTE_Human0.90354361
139ZNF217_24962896_ChIP-Seq_MCF-7_Human0.88262686
140KDM2B_26808549_Chip-Seq_REH_Human0.85585753
141SOX9_26525672_Chip-Seq_HEART_Mouse0.84590222
142NR3C1_21868756_ChIP-Seq_MCF10A_Human0.83996021
143TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83671657

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern6.25287681
2MP0004859_abnormal_synaptic_plasticity6.15125593
3MP0003635_abnormal_synaptic_transmissio4.17031539
4MP0009745_abnormal_behavioral_response3.59172039
5MP0002653_abnormal_ependyma_morphology3.52744644
6MP0004270_analgesia3.46618662
7MP0002063_abnormal_learning/memory/cond3.39735126
8MP0003011_delayed_dark_adaptation3.32362600
9MP0002064_seizures3.27756955
10MP0001968_abnormal_touch/_nociception3.11815368
11MP0009046_muscle_twitch3.07562808
12MP0002572_abnormal_emotion/affect_behav2.96141563
13MP0008877_abnormal_DNA_methylation2.77063634
14MP0002822_catalepsy2.76174779
15MP0002272_abnormal_nervous_system2.70647070
16MP0002736_abnormal_nociception_after2.67651347
17MP0004782_abnormal_surfactant_physiolog2.62411295
18MP0001501_abnormal_sleep_pattern2.60362711
19MP0005423_abnormal_somatic_nervous2.48553296
20MP0001486_abnormal_startle_reflex2.44973906
21MP0002734_abnormal_mechanical_nocicepti2.40003717
22MP0002735_abnormal_chemical_nociception2.39921032
23MP0001440_abnormal_grooming_behavior2.37866309
24MP0006276_abnormal_autonomic_nervous2.16449774
25MP0002733_abnormal_thermal_nociception2.01974199
26MP0002067_abnormal_sensory_capabilities2.01121625
27MP0001970_abnormal_pain_threshold1.94258144
28MP0001529_abnormal_vocalization1.88256709
29MP0003195_calcinosis1.88217740
30MP0003329_amyloid_beta_deposits1.77792675
31MP0002184_abnormal_innervation1.76153063
32MP0004924_abnormal_behavior1.73454638
33MP0005386_behavior/neurological_phenoty1.73454638
34MP0009780_abnormal_chondrocyte_physiolo1.72805024
35MP0003879_abnormal_hair_cell1.71882154
36MP0002837_dystrophic_cardiac_calcinosis1.71097994
37MP0002557_abnormal_social/conspecific_i1.68666465
38MP0002332_abnormal_exercise_endurance1.68229791
39MP0002102_abnormal_ear_morphology1.68184388
40MP0001905_abnormal_dopamine_level1.67587038
41MP0001984_abnormal_olfaction1.64360497
42MP0000778_abnormal_nervous_system1.63460698
43MP0004142_abnormal_muscle_tone1.59781425
44MP0005646_abnormal_pituitary_gland1.57392166
45MP0003787_abnormal_imprinting1.55633419
46MP0008569_lethality_at_weaning1.54062036
47MP0004811_abnormal_neuron_physiology1.53934776
48MP0002909_abnormal_adrenal_gland1.49998695
49MP0003646_muscle_fatigue1.49048951
50MP0003122_maternal_imprinting1.45260747
51MP0000955_abnormal_spinal_cord1.42945050
52MP0004858_abnormal_nervous_system1.41231372
53MP0002066_abnormal_motor_capabilities/c1.37651242
54MP0001188_hyperpigmentation1.36693637
55MP0005253_abnormal_eye_physiology1.36562073
56MP0008875_abnormal_xenobiotic_pharmacok1.35442976
57MP0003136_yellow_coat_color1.32719167
58MP0001502_abnormal_circadian_rhythm1.31583693
59MP0002882_abnormal_neuron_morphology1.31393854
60MP0003121_genomic_imprinting1.28965570
61MP0002160_abnormal_reproductive_system1.23353357
62MP0005084_abnormal_gallbladder_morpholo1.21321197
63MP0008789_abnormal_olfactory_epithelium1.16941455
64MP0006292_abnormal_olfactory_placode1.16133674
65MP0003633_abnormal_nervous_system1.15413660
66MP0000751_myopathy1.14413092
67MP0002876_abnormal_thyroid_physiology1.04835600
68MP0004147_increased_porphyrin_level1.04273369
69MP0008872_abnormal_physiological_respon1.03082155
70MP0003631_nervous_system_phenotype1.00636448
71MP0010386_abnormal_urinary_bladder0.99516183
72MP0005389_reproductive_system_phenotype0.98740521
73MP0005535_abnormal_body_temperature0.97746549
74MP0005645_abnormal_hypothalamus_physiol0.97031329
75MP0006036_abnormal_mitochondrial_physio0.96038386
76MP0002152_abnormal_brain_morphology0.95996503
77MP0000013_abnormal_adipose_tissue0.95928441
78MP0000566_synostosis0.95743698
79MP0002229_neurodegeneration0.92110664
80MP0004885_abnormal_endolymph0.92063875
81MP0008874_decreased_physiological_sensi0.91642028
82MP0004145_abnormal_muscle_electrophysio0.91403535
83MP0002069_abnormal_eating/drinking_beha0.90756544
84MP0004742_abnormal_vestibular_system0.90401115
85MP0005551_abnormal_eye_electrophysiolog0.89068718
86MP0000427_abnormal_hair_cycle0.88129867
87MP0004085_abnormal_heartbeat0.87724459
88MP0001963_abnormal_hearing_physiology0.86739967
89MP0002163_abnormal_gland_morphology0.82467277
90MP0004484_altered_response_of0.81230187
91MP0003890_abnormal_embryonic-extraembry0.80710892
92MP0003698_abnormal_male_reproductive0.80645734
93MP0000049_abnormal_middle_ear0.80224527
94MP0000604_amyloidosis0.79453040
95MP0004215_abnormal_myocardial_fiber0.78973451
96MP0005332_abnormal_amino_acid0.78801828
97MP0005195_abnormal_posterior_eye0.78492041
98MP0005085_abnormal_gallbladder_physiolo0.77341938
99MP0000372_irregular_coat_pigmentation0.76730459
100MP0005266_abnormal_metabolism0.76683352
101MP0004133_heterotaxia0.75419981
102MP0001664_abnormal_digestion0.75200879
103MP0001293_anophthalmia0.75065188
104MP0005409_darkened_coat_color0.73399657
105MP0002210_abnormal_sex_determination0.73138791
106MP0002752_abnormal_somatic_nervous0.71871136
107MP0005394_taste/olfaction_phenotype0.70582468
108MP0005499_abnormal_olfactory_system0.70582468
109MP0000631_abnormal_neuroendocrine_gland0.65030371
110MP0001485_abnormal_pinna_reflex0.64890890
111MP0003632_abnormal_nervous_system0.64527466
112MP0005171_absent_coat_pigmentation0.63246312
113MP0001177_atelectasis0.62420348
114MP0003634_abnormal_glial_cell0.61873407
115MP0003075_altered_response_to0.61267197
116MP0005623_abnormal_meninges_morphology0.59244054
117MP0001986_abnormal_taste_sensitivity0.57019801
118MP0001765_abnormal_ion_homeostasis0.56687164
119MP0004233_abnormal_muscle_weight0.55925225
120MP0001943_abnormal_respiration0.55164376
121MP0002090_abnormal_vision0.54489349
122MP0000026_abnormal_inner_ear0.54009290
123MP0002638_abnormal_pupillary_reflex0.52668896
124MP0005379_endocrine/exocrine_gland_phen0.50038017
125MP0006035_abnormal_mitochondrial_morpho0.49084277
126MP0003137_abnormal_impulse_conducting0.49068595
127MP0003123_paternal_imprinting0.48694775
128MP0003956_abnormal_body_size0.48330428
129MP0000920_abnormal_myelination0.47931392
130MP0006072_abnormal_retinal_apoptosis0.46972209
131MP0004043_abnormal_pH_regulation0.46365998
132MP0010234_abnormal_vibrissa_follicle0.44962493
133MP0010769_abnormal_survival0.44520255

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.77040001
2Myokymia (HP:0002411)6.75215831
3Focal seizures (HP:0007359)6.01376655
4Atonic seizures (HP:0010819)5.92901586
5Epileptic encephalopathy (HP:0200134)5.63513263
6Visual hallucinations (HP:0002367)5.46524256
7Febrile seizures (HP:0002373)5.04794779
8Absence seizures (HP:0002121)4.87101039
9Dialeptic seizures (HP:0011146)4.45870474
10Hyperventilation (HP:0002883)4.28915204
11Progressive cerebellar ataxia (HP:0002073)4.12068549
12Generalized tonic-clonic seizures (HP:0002069)4.08621899
13Amblyopia (HP:0000646)3.74139136
14Molar tooth sign on MRI (HP:0002419)3.52587626
15Abnormality of midbrain morphology (HP:0002418)3.52587626
16Congenital stationary night blindness (HP:0007642)3.50067415
17Broad-based gait (HP:0002136)3.48109005
18Supranuclear gaze palsy (HP:0000605)3.21413710
19Poor eye contact (HP:0000817)3.21142199
20Abnormality of the labia minora (HP:0012880)3.14936832
21Gaze-evoked nystagmus (HP:0000640)3.13766923
22Chronic hepatic failure (HP:0100626)3.08087821
23Retinal dysplasia (HP:0007973)3.07694146
24Anxiety (HP:0000739)3.02578992
25Impaired vibration sensation in the lower limbs (HP:0002166)3.01937239
26Action tremor (HP:0002345)2.96247414
27Acute necrotizing encephalopathy (HP:0006965)2.96153993
28Dysdiadochokinesis (HP:0002075)2.95927473
29Epileptiform EEG discharges (HP:0011182)2.86645604
30Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.86273193
31Decreased activity of mitochondrial respiratory chain (HP:0008972)2.86273193
32Dysmetria (HP:0001310)2.86121581
33Impaired social interactions (HP:0000735)2.85549702
34Abnormal social behavior (HP:0012433)2.85549702
35Pancreatic fibrosis (HP:0100732)2.85027487
36True hermaphroditism (HP:0010459)2.84755873
37Abnormal eating behavior (HP:0100738)2.80297606
38Pancreatic cysts (HP:0001737)2.79538668
39Truncal ataxia (HP:0002078)2.78845670
40Large for gestational age (HP:0001520)2.75840524
41Depression (HP:0000716)2.74132883
42Cerebral inclusion bodies (HP:0100314)2.73988324
43Abnormal mitochondria in muscle tissue (HP:0008316)2.72909844
44Excessive salivation (HP:0003781)2.65752387
45Drooling (HP:0002307)2.65752387
46Progressive macrocephaly (HP:0004481)2.65486352
47Dyskinesia (HP:0100660)2.65319440
48Delusions (HP:0000746)2.62537217
49Nephronophthisis (HP:0000090)2.62401037
50Type II lissencephaly (HP:0007260)2.61381571
51EEG with generalized epileptiform discharges (HP:0011198)2.58036008
52Progressive inability to walk (HP:0002505)2.55740743
53Urinary bladder sphincter dysfunction (HP:0002839)2.54676951
54Rib fusion (HP:0000902)2.54333056
55Lissencephaly (HP:0001339)2.52431944
56Abnormality of the lower motor neuron (HP:0002366)2.49970155
57Ankle clonus (HP:0011448)2.48254889
58Pheochromocytoma (HP:0002666)2.48242178
59Inability to walk (HP:0002540)2.47990419
60Hepatic necrosis (HP:0002605)2.42420735
61Limb dystonia (HP:0002451)2.41495248
62Agitation (HP:0000713)2.41410927
63Mitochondrial inheritance (HP:0001427)2.40831917
64Sclerocornea (HP:0000647)2.39101895
65Abnormality of the renal cortex (HP:0011035)2.38305359
66Status epilepticus (HP:0002133)2.38155366
67Increased hepatocellular lipid droplets (HP:0006565)2.36812691
68Polyphagia (HP:0002591)2.36523072
69Hypsarrhythmia (HP:0002521)2.36259560
70Pachygyria (HP:0001302)2.34997368
71Renal cortical cysts (HP:0000803)2.33723473
72Cheilitis (HP:0100825)2.32527888
73Bradykinesia (HP:0002067)2.32352489
74Scanning speech (HP:0002168)2.27899325
75Generalized myoclonic seizures (HP:0002123)2.27715799
76Neuroendocrine neoplasm (HP:0100634)2.27632062
77Abnormality of macular pigmentation (HP:0008002)2.26339231
78Fetal akinesia sequence (HP:0001989)2.26182255
79Termporal pattern (HP:0011008)2.25387977
80Insidious onset (HP:0003587)2.25387977
81Stereotypic behavior (HP:0000733)2.23843591
82Absent speech (HP:0001344)2.22776763
83Impaired smooth pursuit (HP:0007772)2.22256871
84Postural instability (HP:0002172)2.22245965
85Acute encephalopathy (HP:0006846)2.22108554
86Focal dystonia (HP:0004373)2.21357069
87Torticollis (HP:0000473)2.20221444
88Poor suck (HP:0002033)2.18523922
89Abnormality of binocular vision (HP:0011514)2.18085097
90Diplopia (HP:0000651)2.18085097
91Abnormal hair whorl (HP:0010721)2.17789259
92Decreased circulating renin level (HP:0003351)2.16428830
93Gait imbalance (HP:0002141)2.15942731
94Lipid accumulation in hepatocytes (HP:0006561)2.14474939
95Hemiparesis (HP:0001269)2.12926948
96Urinary urgency (HP:0000012)2.12650304
97Megaloblastic anemia (HP:0001889)2.10745333
98Impaired vibratory sensation (HP:0002495)2.07566502
99Spastic gait (HP:0002064)2.06377546
100Genetic anticipation (HP:0003743)2.05551449
101Dynein arm defect of respiratory motile cilia (HP:0012255)2.05189298
102Absent/shortened dynein arms (HP:0200106)2.05189298
103Genital tract atresia (HP:0001827)2.04067360
104Neurofibrillary tangles (HP:0002185)2.02362253
105Renal Fanconi syndrome (HP:0001994)2.01062716
106Psychosis (HP:0000709)2.00641265
107Abnormality of the renal medulla (HP:0100957)1.99780521
108Mutism (HP:0002300)1.99168724
109Increased CSF lactate (HP:0002490)1.98774766
110Increased intramyocellular lipid droplets (HP:0012240)1.98493224
111Vaginal atresia (HP:0000148)1.96677623
112Polydipsia (HP:0001959)1.96434594
113Abnormal drinking behavior (HP:0030082)1.96434594
114Cystic liver disease (HP:0006706)1.96210171
115Protruding tongue (HP:0010808)1.95475737
116Craniofacial dystonia (HP:0012179)1.95416932
117Dysmetric saccades (HP:0000641)1.95321886
118Incomplete penetrance (HP:0003829)1.95277778
119Spastic tetraplegia (HP:0002510)1.95037121
120Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.94964100
121Failure to thrive in infancy (HP:0001531)1.94617153
122Resting tremor (HP:0002322)1.92620186
123Abnormal rod and cone electroretinograms (HP:0008323)1.92351327
124Medial flaring of the eyebrow (HP:0010747)1.91830771
125Synostosis involving the elbow (HP:0003938)1.91598513
126Humeroradial synostosis (HP:0003041)1.91598513
127Hypoventilation (HP:0002791)1.90928873
128Abolished electroretinogram (ERG) (HP:0000550)1.90667918
129Congenital primary aphakia (HP:0007707)1.89555174
130Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.87168928
131Esotropia (HP:0000565)1.87136503
132Ulnar claw (HP:0001178)1.86499822
133Optic nerve hypoplasia (HP:0000609)1.86478450
134Tachypnea (HP:0002789)1.85347034
135Methylmalonic acidemia (HP:0002912)1.84710784
136Hyperthyroidism (HP:0000836)1.83922459
137Optic disc pallor (HP:0000543)1.83713961
138Abnormality of the corticospinal tract (HP:0002492)1.83663065
139Abnormality of ocular smooth pursuit (HP:0000617)1.82235838
140Hypoplasia of the fovea (HP:0007750)1.81488824
141Aplasia/Hypoplasia of the fovea (HP:0008060)1.81488824
142Blue irides (HP:0000635)1.80936687
143Abnormality of urine glucose concentration (HP:0011016)1.80919312
144Glycosuria (HP:0003076)1.80919312
145Decreased electroretinogram (ERG) amplitude (HP:0000654)1.78579161
146Methylmalonic aciduria (HP:0012120)1.78102826
147Morphological abnormality of the pyramidal tract (HP:0002062)1.77925070
148Lower limb muscle weakness (HP:0007340)1.77593755
149Abnormality of salivation (HP:0100755)1.77506283
150Hypomagnesemia (HP:0002917)1.77187973
151Gait ataxia (HP:0002066)1.77088620
152Abnormal respiratory motile cilium morphology (HP:0005938)1.76827975
153Abnormal respiratory epithelium morphology (HP:0012253)1.76827975
154Generalized aminoaciduria (HP:0002909)1.76167165
155Specific learning disability (HP:0001328)1.74942233
156Conical tooth (HP:0000698)1.74540749
157Rapidly progressive (HP:0003678)1.74294085
158Severe muscular hypotonia (HP:0006829)1.74081824
159Akinesia (HP:0002304)1.73860062
160Abnormality of the fovea (HP:0000493)1.73116173
161Hypoalbuminemia (HP:0003073)1.73099897
162Abnormal albumin level (HP:0012116)1.73099897
163Hepatocellular necrosis (HP:0001404)1.72794719
164Thickened helices (HP:0000391)1.72786634
165Abnormality of eosinophils (HP:0001879)1.72100308
166Nephrogenic diabetes insipidus (HP:0009806)1.71984912

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.15586876
2NTRK34.51088181
3MAP3K93.40217762
4MAP3K123.28994895
5CASK3.24515569
6TLK13.12337093
7MAP3K43.06873878
8MAP2K72.81378178
9FRK2.64268872
10RIPK42.58459295
11MINK12.52265019
12DAPK22.48575270
13BMPR1B2.40350028
14WNK32.31536354
15PLK22.30387133
16MAP4K22.17013769
17ARAF2.12564724
18MAP2K42.07192974
19DAPK12.04626969
20KSR21.97041908
21GRK51.94120911
22GRK11.87505056
23BCKDK1.86407304
24CDK191.83935022
25MARK11.80306984
26FGFR21.79862444
27KSR11.77995095
28PNCK1.71655171
29TRIM281.68765900
30PAK61.61068302
31NME11.55167457
32DYRK21.53593970
33CSNK1G31.46267427
34NTRK21.42658252
35MAP3K131.39179601
36PTK2B1.36092367
37CDK51.34999144
38OBSCN1.34015965
39BMPR21.33733662
40NTRK11.32304149
41PRPF4B1.31524042
42TNIK1.27744258
43PRKCG1.24271238
44SIK21.21529802
45CSNK1A1L1.21420577
46CAMK2A1.19811291
47MAPK131.16944740
48CSNK1G11.16052472
49INSRR1.15537792
50CAMKK11.14491779
51FES1.14384133
52STK161.12341759
53RAF11.10552597
54CAMKK21.07615771
55MUSK1.06569789
56PRKD31.04944814
57OXSR11.04780863
58ZAK1.02099301
59CAMK2B1.01321836
60PIK3CA1.00890056
61SIK31.00432111
62FGR0.96475013
63MAP2K60.96208211
64MAP3K20.93303506
65CCNB10.93137097
66CDK180.90751525
67LIMK10.90533057
68TAOK30.89622382
69UHMK10.87439480
70ERBB30.86487589
71CDK140.84642912
72CDK150.84232203
73IRAK40.77655692
74BRAF0.77581379
75CDK11A0.73728466
76SGK4940.73531000
77SGK2230.73531000
78GRK60.72782484
79RPS6KA50.72354731
80CSNK1A10.71681328
81MAPK150.71228509
82CAMK10.70160878
83STK380.69736525
84GRK70.69226659
85BCR0.68912055
86DYRK1A0.67296602
87AKT30.65771309
88TYRO30.63343788
89PRKCI0.63264253
90TIE10.60390251
91SGK10.59592608
92PRKCE0.59243421
93MAP3K60.58606941
94DAPK30.57953475
95MAPKAPK50.57147610
96PIM20.56923386
97SGK20.56376224
98PAK30.56195192
99PKN10.55600662
100LATS20.55536638
101STK110.55298478
102CSNK1D0.54761577
103CAMK2D0.53274618
104CSNK1G20.53050696
105MAP3K10.52966663
106PDPK10.52759342
107CAMK2G0.52652623
108FGFR10.52208146
109RET0.51631406
110MAP3K110.51405842
111PDK10.51334426
112ADRBK10.50400201
113MAP2K10.50399260
114PRKCH0.48426907
115FER0.47842153
116TGFBR10.46264634
117MARK20.44971863
118MAPKAPK30.43643874
119TNK20.43035060
120PHKG20.42568689
121PHKG10.42568689
122MOS0.41650927
123WNK40.41180765
124TAOK10.41079756
125DYRK30.41077962
126ADRBK20.40602481
127PLK10.39456201
128PRKCZ0.39373497
129NUAK10.38128421
130ROCK20.37614093
131PRKACB0.37132147
132ACVR1B0.36339451
133PINK10.35098569
134PRKACA0.34114263
135RPS6KA30.33446006
136MAP2K20.33429630
137PRKAA10.32572227
138MAPK120.30825522
139PRKG10.30651904
140FYN0.30472187
141TSSK60.30236984
142PRKCA0.29949525
143STK390.29274671
144SGK30.29207797
145MYLK0.28977339
146PDK30.28499246

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.99844881
2Synaptic vesicle cycle_Homo sapiens_hsa047213.70400554
3Long-term potentiation_Homo sapiens_hsa047202.86159786
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.85687350
5Circadian entrainment_Homo sapiens_hsa047132.72534267
6Linoleic acid metabolism_Homo sapiens_hsa005912.68592300
7Amphetamine addiction_Homo sapiens_hsa050312.66363939
8Collecting duct acid secretion_Homo sapiens_hsa049662.63990011
9Olfactory transduction_Homo sapiens_hsa047402.62800627
10Ether lipid metabolism_Homo sapiens_hsa005652.60458851
11GABAergic synapse_Homo sapiens_hsa047272.56512509
12Folate biosynthesis_Homo sapiens_hsa007902.53313899
13Morphine addiction_Homo sapiens_hsa050322.52111055
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.49194905
15Glutamatergic synapse_Homo sapiens_hsa047242.44422628
16Caffeine metabolism_Homo sapiens_hsa002322.41194121
17Sulfur relay system_Homo sapiens_hsa041222.39478123
18Nitrogen metabolism_Homo sapiens_hsa009102.26734715
19Dopaminergic synapse_Homo sapiens_hsa047282.24510933
20Oxidative phosphorylation_Homo sapiens_hsa001902.22913674
21Salivary secretion_Homo sapiens_hsa049702.19549201
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.07031163
23Taste transduction_Homo sapiens_hsa047422.00299633
24Serotonergic synapse_Homo sapiens_hsa047261.87956902
25Insulin secretion_Homo sapiens_hsa049111.86601147
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.84525994
27Renin secretion_Homo sapiens_hsa049241.82241972
28Cholinergic synapse_Homo sapiens_hsa047251.77168287
29Long-term depression_Homo sapiens_hsa047301.75251890
30Gastric acid secretion_Homo sapiens_hsa049711.73152727
31Alzheimers disease_Homo sapiens_hsa050101.71363770
32Parkinsons disease_Homo sapiens_hsa050121.68042169
33Calcium signaling pathway_Homo sapiens_hsa040201.67761482
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66306994
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65310552
36Vibrio cholerae infection_Homo sapiens_hsa051101.64860252
37Oxytocin signaling pathway_Homo sapiens_hsa049211.63295624
38Cocaine addiction_Homo sapiens_hsa050301.61364242
39Selenocompound metabolism_Homo sapiens_hsa004501.61177277
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.58368042
41Cardiac muscle contraction_Homo sapiens_hsa042601.56057345
42Tryptophan metabolism_Homo sapiens_hsa003801.49710056
43Protein export_Homo sapiens_hsa030601.48945221
44Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46261814
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.43713574
46GnRH signaling pathway_Homo sapiens_hsa049121.37822368
47One carbon pool by folate_Homo sapiens_hsa006701.35944241
48Butanoate metabolism_Homo sapiens_hsa006501.30657903
49Gap junction_Homo sapiens_hsa045401.28897403
50Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25788798
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.23136893
52Huntingtons disease_Homo sapiens_hsa050161.17794927
53Vitamin digestion and absorption_Homo sapiens_hsa049771.17073703
54cAMP signaling pathway_Homo sapiens_hsa040241.13569393
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.12916823
56Regulation of autophagy_Homo sapiens_hsa041401.10589230
57Phototransduction_Homo sapiens_hsa047441.06889512
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05272538
59Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01552141
60Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.00106106
61Estrogen signaling pathway_Homo sapiens_hsa049150.99907214
62Melanogenesis_Homo sapiens_hsa049160.95771721
63cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95603519
64Fatty acid elongation_Homo sapiens_hsa000620.93525961
65Axon guidance_Homo sapiens_hsa043600.92615155
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.91632120
67Glioma_Homo sapiens_hsa052140.90324948
68Mineral absorption_Homo sapiens_hsa049780.90212638
69Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.87012406
70Arachidonic acid metabolism_Homo sapiens_hsa005900.82681679
71Peroxisome_Homo sapiens_hsa041460.81849946
72Type II diabetes mellitus_Homo sapiens_hsa049300.80348163
73Steroid biosynthesis_Homo sapiens_hsa001000.79790610
74ErbB signaling pathway_Homo sapiens_hsa040120.79698772
75Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.78867541
76Oocyte meiosis_Homo sapiens_hsa041140.78463938
77Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76992609
78Pancreatic secretion_Homo sapiens_hsa049720.76373763
79Glycerophospholipid metabolism_Homo sapiens_hsa005640.73191300
80Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.72739275
81Fat digestion and absorption_Homo sapiens_hsa049750.70509432
82beta-Alanine metabolism_Homo sapiens_hsa004100.69776813
83Retinol metabolism_Homo sapiens_hsa008300.67505239
84Primary bile acid biosynthesis_Homo sapiens_hsa001200.64924526
85Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.64814103
86Rheumatoid arthritis_Homo sapiens_hsa053230.63930637
87Thyroid hormone synthesis_Homo sapiens_hsa049180.62632184
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61504197
89Propanoate metabolism_Homo sapiens_hsa006400.61052656
90Basal transcription factors_Homo sapiens_hsa030220.60004744
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58219393
92ABC transporters_Homo sapiens_hsa020100.57200337
93Metabolic pathways_Homo sapiens_hsa011000.56788938
94Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56121363
95Glucagon signaling pathway_Homo sapiens_hsa049220.55937955
96MAPK signaling pathway_Homo sapiens_hsa040100.54571863
97Choline metabolism in cancer_Homo sapiens_hsa052310.54555581
98Dilated cardiomyopathy_Homo sapiens_hsa054140.53948206
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.53766657
100Arginine and proline metabolism_Homo sapiens_hsa003300.53163832
101Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52272275
102Dorso-ventral axis formation_Homo sapiens_hsa043200.52052289
103Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.51872607
104RNA polymerase_Homo sapiens_hsa030200.51473755
105African trypanosomiasis_Homo sapiens_hsa051430.50124895
106VEGF signaling pathway_Homo sapiens_hsa043700.48820964
107Alcoholism_Homo sapiens_hsa050340.48337498
108Ras signaling pathway_Homo sapiens_hsa040140.47515823
109Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.45359793
110Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.44800038
111Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44528836
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44157936
113Type I diabetes mellitus_Homo sapiens_hsa049400.43643057
114Inositol phosphate metabolism_Homo sapiens_hsa005620.41948027
115Ribosome_Homo sapiens_hsa030100.41215954
116Circadian rhythm_Homo sapiens_hsa047100.40961124
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.40264523
118Neurotrophin signaling pathway_Homo sapiens_hsa047220.39904964
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39190704
120Rap1 signaling pathway_Homo sapiens_hsa040150.36934350
121SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36667535
122Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36530992
123Chemical carcinogenesis_Homo sapiens_hsa052040.35342614
124Prion diseases_Homo sapiens_hsa050200.35267925
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.34736233
126Phagosome_Homo sapiens_hsa041450.33742163
127Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33486472
128Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.33245761
129Glycerolipid metabolism_Homo sapiens_hsa005610.33067668
130Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32417387
131Proteasome_Homo sapiens_hsa030500.31252762
132Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.30947186
133Sulfur metabolism_Homo sapiens_hsa009200.29330394
134RNA degradation_Homo sapiens_hsa030180.27433338
135Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.26654509
136Wnt signaling pathway_Homo sapiens_hsa043100.25367547
137Histidine metabolism_Homo sapiens_hsa003400.24719099
138Pyruvate metabolism_Homo sapiens_hsa006200.23680105
139Endocytosis_Homo sapiens_hsa041440.21446090
140Thyroid hormone signaling pathway_Homo sapiens_hsa049190.21163904
141Insulin signaling pathway_Homo sapiens_hsa049100.20619203
142Non-small cell lung cancer_Homo sapiens_hsa052230.20460492
143Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.19808739
144Ovarian steroidogenesis_Homo sapiens_hsa049130.19514141
145Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.18992993
146Renal cell carcinoma_Homo sapiens_hsa052110.17895439
147Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.17503515
148Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.16728783
149Bile secretion_Homo sapiens_hsa049760.16672408
150Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.15679916

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