

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | modulation by symbiont of host defense response (GO:0052031) | 6.14082575 |
| 2 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.14082575 |
| 3 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.14082575 |
| 4 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.14082575 |
| 5 | modulation by symbiont of host immune response (GO:0052553) | 6.14082575 |
| 6 | positive regulation by symbiont of host defense response (GO:0052509) | 6.14082575 |
| 7 | neutrophil activation involved in immune response (GO:0002283) | 5.98062633 |
| 8 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.60971614 |
| 9 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.60912118 |
| 10 | negative regulation of cell killing (GO:0031342) | 5.60912118 |
| 11 | cellular extravasation (GO:0045123) | 5.46856985 |
| 12 | leukocyte migration involved in inflammatory response (GO:0002523) | 5.35250238 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.15967037 |
| 14 | response to peptidoglycan (GO:0032494) | 4.96366346 |
| 15 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.93348836 |
| 16 | neutrophil activation (GO:0042119) | 4.89376490 |
| 17 | leukocyte aggregation (GO:0070486) | 4.88055998 |
| 18 | detection of other organism (GO:0098543) | 4.86873559 |
| 19 | macrophage activation involved in immune response (GO:0002281) | 4.78867641 |
| 20 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.77212125 |
| 21 | detection of molecule of bacterial origin (GO:0032490) | 4.74145400 |
| 22 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.71641472 |
| 23 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.59202015 |
| 24 | microglial cell activation (GO:0001774) | 4.58398048 |
| 25 | detection of bacterium (GO:0016045) | 4.54546944 |
| 26 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.49495545 |
| 27 | detection of external biotic stimulus (GO:0098581) | 4.43776265 |
| 28 | response to interleukin-15 (GO:0070672) | 4.39637803 |
| 29 | neutrophil mediated immunity (GO:0002446) | 4.28578386 |
| 30 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.25885743 |
| 31 | response to host immune response (GO:0052572) | 4.25885743 |
| 32 | granulocyte activation (GO:0036230) | 4.25261534 |
| 33 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.23682396 |
| 34 | cellular response to interleukin-15 (GO:0071350) | 4.21902346 |
| 35 | respiratory burst (GO:0045730) | 4.21149060 |
| 36 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.20364969 |
| 37 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.17302671 |
| 38 | negative regulation of interleukin-12 production (GO:0032695) | 4.09418604 |
| 39 | immunoglobulin mediated immune response (GO:0016064) | 4.00878268 |
| 40 | regulation of mast cell degranulation (GO:0043304) | 3.99619293 |
| 41 | macrophage activation (GO:0042116) | 3.95277322 |
| 42 | myeloid cell activation involved in immune response (GO:0002275) | 3.91563235 |
| 43 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.84182241 |
| 44 | detection of biotic stimulus (GO:0009595) | 3.81360001 |
| 45 | leukocyte degranulation (GO:0043299) | 3.79296416 |
| 46 | regulation of gamma-delta T cell activation (GO:0046643) | 3.79254028 |
| 47 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.75063056 |
| 48 | response to host (GO:0075136) | 3.74996543 |
| 49 | response to host defenses (GO:0052200) | 3.74996543 |
| 50 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.74996543 |
| 51 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.72689780 |
| 52 | myeloid leukocyte mediated immunity (GO:0002444) | 3.68609420 |
| 53 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.65587347 |
| 54 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.61101763 |
| 55 | regulation of mast cell activation (GO:0033003) | 3.58725758 |
| 56 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.56478835 |
| 57 | negative regulation of phagocytosis (GO:0050765) | 3.47500693 |
| 58 | negative regulation of T cell mediated immunity (GO:0002710) | 3.45028915 |
| 59 | defense response to protozoan (GO:0042832) | 3.44155635 |
| 60 | positive regulation of mast cell activation (GO:0033005) | 3.42576775 |
| 61 | type I interferon signaling pathway (GO:0060337) | 3.41974746 |
| 62 | cellular response to type I interferon (GO:0071357) | 3.41974746 |
| 63 | response to type I interferon (GO:0034340) | 3.40722613 |
| 64 | regulation of memory T cell differentiation (GO:0043380) | 3.40404047 |
| 65 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.38112266 |
| 66 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.38112266 |
| 67 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.37315466 |
| 68 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.32805751 |
| 69 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.31457359 |
| 70 | negative regulation of interleukin-6 production (GO:0032715) | 3.26988964 |
| 71 | positive regulation of B cell differentiation (GO:0045579) | 3.23574823 |
| 72 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.22583376 |
| 73 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.21168191 |
| 74 | regulation of leukocyte degranulation (GO:0043300) | 3.15729697 |
| 75 | B cell mediated immunity (GO:0019724) | 3.12538271 |
| 76 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.12094027 |
| 77 | regulation of B cell differentiation (GO:0045577) | 3.11362637 |
| 78 | response to muramyl dipeptide (GO:0032495) | 3.10875290 |
| 79 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.08650973 |
| 80 | germinal center formation (GO:0002467) | 3.08615993 |
| 81 | B cell receptor signaling pathway (GO:0050853) | 3.07893803 |
| 82 | positive regulation of interferon-alpha production (GO:0032727) | 3.07538746 |
| 83 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.04172076 |
| 84 | neutrophil chemotaxis (GO:0030593) | 3.03938725 |
| 85 | positive regulation of interleukin-17 production (GO:0032740) | 3.01549895 |
| 86 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.00361720 |
| 87 | response to protozoan (GO:0001562) | 2.99064958 |
| 88 | positive regulation of mast cell degranulation (GO:0043306) | 2.98340605 |
| 89 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.98340605 |
| 90 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.97810603 |
| 91 | response to interferon-alpha (GO:0035455) | 2.97009697 |
| 92 | neutrophil migration (GO:1990266) | 2.96294076 |
| 93 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.95533409 |
| 94 | mast cell activation (GO:0045576) | 2.94029112 |
| 95 | negative regulation of innate immune response (GO:0045824) | 2.90584872 |
| 96 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.88987145 |
| 97 | dendritic cell migration (GO:0036336) | 2.88372024 |
| 98 | response to interferon-beta (GO:0035456) | 2.87217534 |
| 99 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.86354777 |
| 100 | regulation of interferon-alpha production (GO:0032647) | 2.86225736 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.59059723 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.99099292 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.09292033 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.50630958 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.14695052 |
| 6 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.04181111 |
| 7 | SPI1_23127762_ChIP-Seq_K562_Human | 2.91950021 |
| 8 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.90429467 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.88210152 |
| 10 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.84530898 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.80202516 |
| 12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.75657812 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.44615977 |
| 14 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.42764472 |
| 15 | MYB_26560356_Chip-Seq_TH2_Human | 2.35307596 |
| 16 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.32722504 |
| 17 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.32552550 |
| 18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.27913566 |
| 19 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.25001195 |
| 20 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.18972132 |
| 21 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.12825367 |
| 22 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.11326517 |
| 23 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.10147352 |
| 24 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 2.09246852 |
| 25 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.06463183 |
| 26 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.03079631 |
| 27 | MAF_26560356_Chip-Seq_TH1_Human | 1.99524148 |
| 28 | UTX_26944678_Chip-Seq_JUKART_Human | 1.96967299 |
| 29 | GATA1_22025678_ChIP-Seq_K562_Human | 1.95040224 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.92676986 |
| 31 | MYB_26560356_Chip-Seq_TH1_Human | 1.91440749 |
| 32 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.88163186 |
| 33 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.86588677 |
| 34 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.85425062 |
| 35 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.85237415 |
| 36 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.81492050 |
| 37 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.78052465 |
| 38 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.71963579 |
| 39 | MAF_26560356_Chip-Seq_TH2_Human | 1.70640458 |
| 40 | GATA3_26560356_Chip-Seq_TH2_Human | 1.68158664 |
| 41 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.65297837 |
| 42 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62984345 |
| 43 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.59878651 |
| 44 | GATA1_19941826_ChIP-Seq_K562_Human | 1.58767063 |
| 45 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.58629081 |
| 46 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.57600765 |
| 47 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.53909698 |
| 48 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.50588197 |
| 49 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.43850435 |
| 50 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.39721892 |
| 51 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.39218347 |
| 52 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.37500279 |
| 53 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.30642905 |
| 54 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.29277627 |
| 55 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.28637338 |
| 56 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.28291735 |
| 57 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.27659924 |
| 58 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.27286468 |
| 59 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.27102363 |
| 60 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.27005751 |
| 61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.26939326 |
| 62 | GATA2_19941826_ChIP-Seq_K562_Human | 1.26782726 |
| 63 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.24723199 |
| 64 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.23526361 |
| 65 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.22948059 |
| 66 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22625225 |
| 67 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22431036 |
| 68 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.21686508 |
| 69 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.20068851 |
| 70 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.17551121 |
| 71 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.17312692 |
| 72 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.17307548 |
| 73 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.15634489 |
| 74 | P300_27268052_Chip-Seq_Bcells_Human | 1.15345896 |
| 75 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.13845322 |
| 76 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.12279944 |
| 77 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.11681786 |
| 78 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09955278 |
| 79 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.08663260 |
| 80 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.07405127 |
| 81 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.05658441 |
| 82 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.05540995 |
| 83 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.05312959 |
| 84 | MYC_22102868_ChIP-Seq_BL_Human | 1.04196709 |
| 85 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.03222127 |
| 86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.02189535 |
| 87 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.01764022 |
| 88 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99665733 |
| 89 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.99236905 |
| 90 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.98914254 |
| 91 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.98691656 |
| 92 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.97151490 |
| 93 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.95951685 |
| 94 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.95835471 |
| 95 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95814769 |
| 96 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94872107 |
| 97 | P68_20966046_ChIP-Seq_HELA_Human | 0.93225323 |
| 98 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92736466 |
| 99 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92057653 |
| 100 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.91811029 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.82031025 |
| 2 | MP0003436_decreased_susceptibility_to | 4.01533370 |
| 3 | MP0003303_peritoneal_inflammation | 3.52733373 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.31864596 |
| 5 | MP0002419_abnormal_innate_immunity | 3.18774329 |
| 6 | MP0002132_abnormal_respiratory_system | 2.99881862 |
| 7 | MP0005025_abnormal_response_to | 2.84523588 |
| 8 | MP0009785_altered_susceptibility_to | 2.83976831 |
| 9 | MP0001800_abnormal_humoral_immune | 2.70066394 |
| 10 | MP0005671_abnormal_response_to | 2.64659552 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.60414975 |
| 12 | MP0005387_immune_system_phenotype | 2.59416567 |
| 13 | MP0001790_abnormal_immune_system | 2.59416567 |
| 14 | MP0002723_abnormal_immune_serum | 2.56832667 |
| 15 | MP0005464_abnormal_platelet_physiology | 2.53445529 |
| 16 | MP0000685_abnormal_immune_system | 2.51189445 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.47709197 |
| 18 | MP0001819_abnormal_immune_cell | 2.45455050 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.30200325 |
| 20 | MP0009278_abnormal_bone_marrow | 2.20141200 |
| 21 | MP0002148_abnormal_hypersensitivity_rea | 2.14065328 |
| 22 | MP0001533_abnormal_skeleton_physiology | 2.03675913 |
| 23 | MP0006082_CNS_inflammation | 2.01961047 |
| 24 | MP0000465_gastrointestinal_hemorrhage | 2.00618074 |
| 25 | MP0002398_abnormal_bone_marrow | 1.91642128 |
| 26 | MP0002405_respiratory_system_inflammati | 1.91223868 |
| 27 | MP0000716_abnormal_immune_system | 1.84263435 |
| 28 | MP0005397_hematopoietic_system_phenotyp | 1.78458318 |
| 29 | MP0001545_abnormal_hematopoietic_system | 1.78458318 |
| 30 | MP0009764_decreased_sensitivity_to | 1.74639025 |
| 31 | MP0002277_abnormal_respiratory_mucosa | 1.73359044 |
| 32 | MP0003191_abnormal_cellular_cholesterol | 1.72359347 |
| 33 | MP0001845_abnormal_inflammatory_respons | 1.67811588 |
| 34 | MP0003300_gastrointestinal_ulcer | 1.66774069 |
| 35 | MP0003763_abnormal_thymus_physiology | 1.64461509 |
| 36 | MP0003806_abnormal_nucleotide_metabolis | 1.62394951 |
| 37 | MP0002396_abnormal_hematopoietic_system | 1.58770165 |
| 38 | MP0000689_abnormal_spleen_morphology | 1.57018562 |
| 39 | MP0002722_abnormal_immune_system | 1.55638540 |
| 40 | MP0008004_abnormal_stomach_pH | 1.51228676 |
| 41 | MP0002429_abnormal_blood_cell | 1.48719411 |
| 42 | MP0010155_abnormal_intestine_physiology | 1.48551798 |
| 43 | MP0008260_abnormal_autophagy | 1.47986239 |
| 44 | MP0008469_abnormal_protein_level | 1.46855849 |
| 45 | MP0003828_pulmonary_edema | 1.46780128 |
| 46 | MP0003866_abnormal_defecation | 1.46429020 |
| 47 | MP0005075_abnormal_melanosome_morpholog | 1.40991625 |
| 48 | MP0003172_abnormal_lysosome_physiology | 1.35351977 |
| 49 | MP0003183_abnormal_peptide_metabolism | 1.34846636 |
| 50 | MP0000703_abnormal_thymus_morphology | 1.31567770 |
| 51 | MP0005410_abnormal_fertilization | 1.30704453 |
| 52 | MP0001986_abnormal_taste_sensitivity | 1.30505827 |
| 53 | MP0003045_fibrosis | 1.28059241 |
| 54 | MP0004883_abnormal_blood_vessel | 1.22345667 |
| 55 | MP0003075_altered_response_to | 1.16761326 |
| 56 | MP0004947_skin_inflammation | 1.13301334 |
| 57 | MP0004381_abnormal_hair_follicle | 1.12178646 |
| 58 | MP0003787_abnormal_imprinting | 1.11713570 |
| 59 | MP0009333_abnormal_splenocyte_physiolog | 1.11220730 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.09929307 |
| 61 | MP0003878_abnormal_ear_physiology | 1.09929307 |
| 62 | MP0005310_abnormal_salivary_gland | 1.09676312 |
| 63 | MP0002928_abnormal_bile_duct | 1.08570373 |
| 64 | MP0005084_abnormal_gallbladder_morpholo | 1.07222690 |
| 65 | MP0003656_abnormal_erythrocyte_physiolo | 1.00573574 |
| 66 | MP0005164_abnormal_response_to | 1.00545477 |
| 67 | MP0001663_abnormal_digestive_system | 0.91896400 |
| 68 | MP0009765_abnormal_xenobiotic_induced | 0.87677452 |
| 69 | MP0005083_abnormal_biliary_tract | 0.87243355 |
| 70 | MP0000858_altered_metastatic_potential | 0.86791550 |
| 71 | MP0004510_myositis | 0.84136813 |
| 72 | MP0002693_abnormal_pancreas_physiology | 0.83895741 |
| 73 | MP0001851_eye_inflammation | 0.80487945 |
| 74 | MP0009763_increased_sensitivity_to | 0.80411172 |
| 75 | MP0002138_abnormal_hepatobiliary_system | 0.76913348 |
| 76 | MP0002998_abnormal_bone_remodeling | 0.75208147 |
| 77 | MP0005166_decreased_susceptibility_to | 0.73597770 |
| 78 | MP0005390_skeleton_phenotype | 0.73130163 |
| 79 | MP0000343_altered_response_to | 0.72868207 |
| 80 | MP0004130_abnormal_muscle_cell | 0.72777422 |
| 81 | MP0000015_abnormal_ear_pigmentation | 0.72564566 |
| 82 | MP0005319_abnormal_enzyme/_coenzyme | 0.71242562 |
| 83 | MP0005535_abnormal_body_temperature | 0.68067919 |
| 84 | MP0005376_homeostasis/metabolism_phenot | 0.65864679 |
| 85 | MP0001764_abnormal_homeostasis | 0.62667707 |
| 86 | MP0005174_abnormal_tail_pigmentation | 0.62201644 |
| 87 | MP0003011_delayed_dark_adaptation | 0.61360271 |
| 88 | MP0001873_stomach_inflammation | 0.60599981 |
| 89 | MP0008874_decreased_physiological_sensi | 0.60323608 |
| 90 | MP0004484_altered_response_of | 0.59568974 |
| 91 | MP0005451_abnormal_body_composition | 0.56972060 |
| 92 | MP0008877_abnormal_DNA_methylation | 0.56094312 |
| 93 | MP0004808_abnormal_hematopoietic_stem | 0.54687810 |
| 94 | MP0003195_calcinosis | 0.53146092 |
| 95 | MP0005167_abnormal_blood-brain_barrier | 0.50688411 |
| 96 | MP0003795_abnormal_bone_structure | 0.49128081 |
| 97 | MP0003638_abnormal_response/metabolism_ | 0.49070790 |
| 98 | MP0009642_abnormal_blood_homeostasis | 0.48108248 |
| 99 | MP0002653_abnormal_ependyma_morphology | 0.48042491 |
| 100 | MP0003252_abnormal_bile_duct | 0.47967927 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myositis (HP:0100614) | 6.06800837 |
| 2 | Eczematoid dermatitis (HP:0000976) | 5.98692556 |
| 3 | Orchitis (HP:0100796) | 5.80707276 |
| 4 | Recurrent abscess formation (HP:0002722) | 5.55594635 |
| 5 | Optic neuritis (HP:0100653) | 5.50116910 |
| 6 | Retrobulbar optic neuritis (HP:0100654) | 5.50116910 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 5.45291777 |
| 8 | Hypochromic microcytic anemia (HP:0004840) | 5.23057343 |
| 9 | Stomatitis (HP:0010280) | 5.00234090 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.86915756 |
| 11 | Chronic obstructive pulmonary disease (HP:0006510) | 4.75876168 |
| 12 | Obstructive lung disease (HP:0006536) | 4.75876168 |
| 13 | Abnormality of macrophages (HP:0004311) | 4.74433338 |
| 14 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.59825274 |
| 15 | Hypochromic anemia (HP:0001931) | 4.23837686 |
| 16 | Gastrointestinal infarctions (HP:0005244) | 4.19634844 |
| 17 | Prolonged bleeding time (HP:0003010) | 4.18826802 |
| 18 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.07239167 |
| 19 | Recurrent fungal infections (HP:0002841) | 3.89104907 |
| 20 | Keratoconjunctivitis sicca (HP:0001097) | 3.88241985 |
| 21 | Encephalitis (HP:0002383) | 3.86297916 |
| 22 | Meningitis (HP:0001287) | 3.78755770 |
| 23 | Episodic fever (HP:0001954) | 3.67766020 |
| 24 | Keratoconjunctivitis (HP:0001096) | 3.67177918 |
| 25 | Recurrent skin infections (HP:0001581) | 3.62488145 |
| 26 | Mediastinal lymphadenopathy (HP:0100721) | 3.59890189 |
| 27 | Vasculitis (HP:0002633) | 3.39296252 |
| 28 | Urticaria (HP:0001025) | 3.36441836 |
| 29 | Spontaneous hematomas (HP:0007420) | 3.35039971 |
| 30 | Petechiae (HP:0000967) | 3.32718054 |
| 31 | Gingivitis (HP:0000230) | 3.26386208 |
| 32 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.24536444 |
| 33 | Recurrent cutaneous fungal infections (HP:0011370) | 3.22119322 |
| 34 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.22119322 |
| 35 | Chest pain (HP:0100749) | 3.14055707 |
| 36 | Increased IgE level (HP:0003212) | 3.13548933 |
| 37 | Hemoptysis (HP:0002105) | 3.08048495 |
| 38 | Anorexia (HP:0002039) | 3.06198921 |
| 39 | Epistaxis (HP:0000421) | 2.96786404 |
| 40 | Microcytic anemia (HP:0001935) | 2.96754504 |
| 41 | Granulocytopenia (HP:0001913) | 2.91229282 |
| 42 | Gingival bleeding (HP:0000225) | 2.90728072 |
| 43 | Arterial thrombosis (HP:0004420) | 2.87264053 |
| 44 | Leukocytosis (HP:0001974) | 2.85585891 |
| 45 | Peritonitis (HP:0002586) | 2.82229816 |
| 46 | Increased IgM level (HP:0003496) | 2.71022925 |
| 47 | Pulmonary infiltrates (HP:0002113) | 2.70903230 |
| 48 | Pulmonary embolism (HP:0002204) | 2.68851241 |
| 49 | Chronic otitis media (HP:0000389) | 2.66509607 |
| 50 | Panhypogammaglobulinemia (HP:0003139) | 2.54880634 |
| 51 | Cellulitis (HP:0100658) | 2.49300717 |
| 52 | Abnormality of T cell physiology (HP:0011840) | 2.48617193 |
| 53 | Abnormality of T cells (HP:0002843) | 2.47218740 |
| 54 | Absent/shortened dynein arms (HP:0200106) | 2.44511909 |
| 55 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.44511909 |
| 56 | Inflammation of the large intestine (HP:0002037) | 2.44483029 |
| 57 | Gangrene (HP:0100758) | 2.43534652 |
| 58 | Gastrointestinal inflammation (HP:0004386) | 2.37390553 |
| 59 | Abnormality of the pleura (HP:0002103) | 2.33690298 |
| 60 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.32281777 |
| 61 | Keratitis (HP:0000491) | 2.30819110 |
| 62 | Eosinophilia (HP:0001880) | 2.29792761 |
| 63 | Ventricular fibrillation (HP:0001663) | 2.29337764 |
| 64 | Abnormality of iron homeostasis (HP:0011031) | 2.28698059 |
| 65 | Abnormality of T cell number (HP:0011839) | 2.27648627 |
| 66 | Purpura (HP:0000979) | 2.24964571 |
| 67 | Acne (HP:0001061) | 2.20650408 |
| 68 | Sepsis (HP:0100806) | 2.19847326 |
| 69 | Pustule (HP:0200039) | 2.17977819 |
| 70 | Abnormal hemoglobin (HP:0011902) | 2.17890041 |
| 71 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.16964633 |
| 72 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.15872848 |
| 73 | Glomerulopathy (HP:0100820) | 2.15517593 |
| 74 | Autoimmune hemolytic anemia (HP:0001890) | 2.12473838 |
| 75 | Hypergammaglobulinemia (HP:0010702) | 2.10633826 |
| 76 | Osteomyelitis (HP:0002754) | 2.08592224 |
| 77 | T lymphocytopenia (HP:0005403) | 2.07868940 |
| 78 | Abnormality of the peritoneum (HP:0002585) | 2.06549419 |
| 79 | Abnormal platelet volume (HP:0011876) | 2.05518371 |
| 80 | Abnormality of the endocardium (HP:0004306) | 2.04538338 |
| 81 | Increased serum ferritin (HP:0003281) | 2.04492810 |
| 82 | Hypertensive crisis (HP:0100735) | 2.04399685 |
| 83 | Stomach cancer (HP:0012126) | 2.03056192 |
| 84 | Abnormality of eosinophils (HP:0001879) | 2.02991048 |
| 85 | Vertigo (HP:0002321) | 1.98900397 |
| 86 | Toxemia of pregnancy (HP:0100603) | 1.96858974 |
| 87 | Polyneuropathy (HP:0001271) | 1.95943936 |
| 88 | Polycythemia (HP:0001901) | 1.94920531 |
| 89 | Severe visual impairment (HP:0001141) | 1.93593129 |
| 90 | Premature loss of primary teeth (HP:0006323) | 1.93205726 |
| 91 | Abnormality of the pericardium (HP:0001697) | 1.92434773 |
| 92 | Skin rash (HP:0000988) | 1.90444910 |
| 93 | Amyloidosis (HP:0011034) | 1.89352082 |
| 94 | Lymphopenia (HP:0001888) | 1.88832795 |
| 95 | Recurrent viral infections (HP:0004429) | 1.87666170 |
| 96 | Cheilitis (HP:0100825) | 1.87312730 |
| 97 | Tetany (HP:0001281) | 1.81393066 |
| 98 | Hepatosplenomegaly (HP:0001433) | 1.80678837 |
| 99 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.78900759 |
| 100 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.78756359 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 5.17017319 |
| 2 | IRAK4 | 3.52196308 |
| 3 | TNK2 | 3.00741797 |
| 4 | MAP2K3 | 2.92428486 |
| 5 | ERN1 | 2.80068872 |
| 6 | BLK | 2.79805545 |
| 7 | MAP4K1 | 2.64211026 |
| 8 | FES | 2.56688913 |
| 9 | GRK6 | 2.47239234 |
| 10 | CSK | 2.43803076 |
| 11 | TAOK3 | 2.39225052 |
| 12 | TYK2 | 2.21006634 |
| 13 | BTK | 2.13048112 |
| 14 | MARK3 | 1.95472048 |
| 15 | ZAP70 | 1.89702305 |
| 16 | EPHB1 | 1.87793288 |
| 17 | TXK | 1.85851339 |
| 18 | HCK | 1.77953547 |
| 19 | SYK | 1.70151083 |
| 20 | TAOK1 | 1.55572269 |
| 21 | IKBKE | 1.52606605 |
| 22 | JAK3 | 1.51320899 |
| 23 | IRAK2 | 1.46935982 |
| 24 | JAK2 | 1.46131038 |
| 25 | PTK2B | 1.44429597 |
| 26 | LYN | 1.42047001 |
| 27 | MATK | 1.40274935 |
| 28 | PINK1 | 1.40108295 |
| 29 | MAP3K3 | 1.39544084 |
| 30 | TEC | 1.38241087 |
| 31 | TBK1 | 1.36668607 |
| 32 | FGR | 1.31851187 |
| 33 | KIT | 1.31682468 |
| 34 | SIK3 | 1.22386284 |
| 35 | MAP3K11 | 1.21533006 |
| 36 | STK38 | 1.19230172 |
| 37 | MAP3K6 | 1.15053809 |
| 38 | DAPK2 | 1.13719596 |
| 39 | IRAK1 | 1.12377258 |
| 40 | MAP3K1 | 1.12270352 |
| 41 | IKBKB | 1.12000608 |
| 42 | SIK2 | 1.09934773 |
| 43 | LCK | 1.08533905 |
| 44 | YES1 | 1.06575918 |
| 45 | CDK19 | 1.06565449 |
| 46 | NLK | 1.03655017 |
| 47 | PRKD2 | 0.99177655 |
| 48 | ITK | 0.98346604 |
| 49 | MARK2 | 0.96269475 |
| 50 | PIK3CG | 0.95517869 |
| 51 | PDK1 | 0.94300704 |
| 52 | KSR2 | 0.93133885 |
| 53 | MAP2K4 | 0.91602612 |
| 54 | MAP3K14 | 0.88700739 |
| 55 | JAK1 | 0.86138294 |
| 56 | PDPK1 | 0.82600680 |
| 57 | FRK | 0.81591740 |
| 58 | MAP3K5 | 0.78644543 |
| 59 | CSF1R | 0.77842831 |
| 60 | SGK3 | 0.76067020 |
| 61 | PRKCQ | 0.72315073 |
| 62 | MAP3K2 | 0.69537672 |
| 63 | MAP3K7 | 0.68802668 |
| 64 | MAP2K2 | 0.64946413 |
| 65 | MAPK7 | 0.63987687 |
| 66 | BMPR2 | 0.61677656 |
| 67 | DYRK1B | 0.59893847 |
| 68 | FYN | 0.59702700 |
| 69 | SGK2 | 0.58934468 |
| 70 | MAP2K6 | 0.57108122 |
| 71 | PRKG2 | 0.56886551 |
| 72 | MAP4K2 | 0.55139467 |
| 73 | DYRK3 | 0.52687050 |
| 74 | NUAK1 | 0.52369160 |
| 75 | MAPK12 | 0.52026993 |
| 76 | STK11 | 0.51634816 |
| 77 | MAPK13 | 0.51397335 |
| 78 | RET | 0.48057854 |
| 79 | PTK6 | 0.44130805 |
| 80 | PIM1 | 0.40608798 |
| 81 | SGK223 | 0.39118891 |
| 82 | SGK494 | 0.39118891 |
| 83 | PRKCH | 0.38231524 |
| 84 | EPHA3 | 0.36897328 |
| 85 | RPS6KA6 | 0.36828878 |
| 86 | RPS6KL1 | 0.36030860 |
| 87 | RPS6KC1 | 0.36030860 |
| 88 | HIPK2 | 0.36000719 |
| 89 | RAF1 | 0.35983516 |
| 90 | RPS6KA1 | 0.35488256 |
| 91 | TESK2 | 0.33738375 |
| 92 | STK10 | 0.31784890 |
| 93 | WNK1 | 0.31132072 |
| 94 | MAPKAPK2 | 0.30555333 |
| 95 | TLK1 | 0.30137714 |
| 96 | ADRBK1 | 0.29649671 |
| 97 | PRKCZ | 0.29176454 |
| 98 | FGFR3 | 0.27710526 |
| 99 | CAMK1 | 0.27630193 |
| 100 | PRKAA2 | 0.26639974 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.30333386 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.28470063 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.04616458 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.43772597 |
| 5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.32618753 |
| 6 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.21076949 |
| 7 | Tuberculosis_Homo sapiens_hsa05152 | 2.19441872 |
| 8 | Malaria_Homo sapiens_hsa05144 | 2.19334125 |
| 9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.18873755 |
| 10 | Legionellosis_Homo sapiens_hsa05134 | 2.09702523 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.05353739 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.02071231 |
| 13 | Measles_Homo sapiens_hsa05162 | 2.01197931 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.00135173 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.99880665 |
| 16 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.97981326 |
| 17 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.86588717 |
| 18 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.85698296 |
| 19 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.81138716 |
| 20 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.76170819 |
| 21 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.72911509 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.71304429 |
| 23 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.69121455 |
| 24 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.65342428 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.60701409 |
| 26 | Phagosome_Homo sapiens_hsa04145 | 1.51316525 |
| 27 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.51024787 |
| 28 | Influenza A_Homo sapiens_hsa05164 | 1.49561427 |
| 29 | Platelet activation_Homo sapiens_hsa04611 | 1.48151638 |
| 30 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.45890975 |
| 31 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.45832316 |
| 32 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.43603061 |
| 33 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.43099210 |
| 34 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.42936992 |
| 35 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.36112136 |
| 36 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.32579861 |
| 37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.29000883 |
| 38 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.23210814 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.15626870 |
| 40 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.10975388 |
| 41 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.09860195 |
| 42 | Hepatitis C_Homo sapiens_hsa05160 | 1.07412829 |
| 43 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.04349132 |
| 44 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.03329097 |
| 45 | Hepatitis B_Homo sapiens_hsa05161 | 1.00368531 |
| 46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.98679914 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.97943260 |
| 48 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.96239855 |
| 49 | Pertussis_Homo sapiens_hsa05133 | 0.94636171 |
| 50 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.94601584 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.92869410 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.90715107 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.86654982 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.84285779 |
| 55 | Viral myocarditis_Homo sapiens_hsa05416 | 0.83114010 |
| 56 | Asthma_Homo sapiens_hsa05310 | 0.78775037 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.77510293 |
| 58 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.74235809 |
| 59 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.72645614 |
| 60 | Shigellosis_Homo sapiens_hsa05131 | 0.70550307 |
| 61 | Other glycan degradation_Homo sapiens_hsa00511 | 0.69976032 |
| 62 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69831738 |
| 63 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.69213768 |
| 64 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.68272545 |
| 65 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.66149044 |
| 66 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.65997062 |
| 67 | Salmonella infection_Homo sapiens_hsa05132 | 0.65285467 |
| 68 | Endocytosis_Homo sapiens_hsa04144 | 0.61129008 |
| 69 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.60428648 |
| 70 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.60057649 |
| 71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.59749422 |
| 72 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.58111652 |
| 73 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.57716102 |
| 74 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.57502174 |
| 75 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.57331036 |
| 76 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.56429708 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53721174 |
| 78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51418714 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49846570 |
| 80 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49794161 |
| 81 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.49283387 |
| 82 | Morphine addiction_Homo sapiens_hsa05032 | 0.48470445 |
| 83 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.47538809 |
| 84 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.47470889 |
| 85 | Insulin resistance_Homo sapiens_hsa04931 | 0.46414393 |
| 86 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43463733 |
| 87 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.42449489 |
| 88 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.41636547 |
| 89 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.40901925 |
| 90 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.40167998 |
| 91 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39288998 |
| 92 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.38187362 |
| 93 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37025911 |
| 94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.34829111 |
| 95 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.33812383 |
| 96 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.33014388 |
| 97 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.31587474 |
| 98 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.29752893 |
| 99 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.28472193 |
| 100 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27749171 |

