LINC01529

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.64804170
2meiotic chromosome segregation (GO:0045132)4.62185339
3mitotic chromosome condensation (GO:0007076)4.37478925
4glucocorticoid receptor signaling pathway (GO:0042921)4.30323896
5DNA topological change (GO:0006265)4.27010125
6regulation of histone H3-K27 methylation (GO:0061085)4.10721772
7nuclear pore complex assembly (GO:0051292)3.97641245
8positive regulation of dendritic spine morphogenesis (GO:0061003)3.95536128
9negative regulation of erythrocyte differentiation (GO:0045647)3.94327941
10regulation of RNA export from nucleus (GO:0046831)3.93982901
11histone H4 deacetylation (GO:0070933)3.93001554
12regulation of NFAT protein import into nucleus (GO:0051532)3.91194770
13histone H3-K36 demethylation (GO:0070544)3.79823466
14positive regulation of gene expression, epigenetic (GO:0045815)3.78256924
15corticosteroid receptor signaling pathway (GO:0031958)3.76980870
16mannose metabolic process (GO:0006013)3.68076964
17negative regulation of histone methylation (GO:0031061)3.67313198
18activation of Rac GTPase activity (GO:0032863)3.65764647
19histone H3-K4 trimethylation (GO:0080182)3.64485844
20regulation of nucleobase-containing compound transport (GO:0032239)3.60330243
21intracellular estrogen receptor signaling pathway (GO:0030520)3.58735333
22receptor catabolic process (GO:0032801)3.55863745
23negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.53800611
24chromosome condensation (GO:0030261)3.53712064
25stress granule assembly (GO:0034063)3.53280184
26histone H3-K4 methylation (GO:0051568)3.50362801
27mitotic sister chromatid segregation (GO:0000070)3.46024903
28sister chromatid segregation (GO:0000819)3.36085790
29regulation of ARF GTPase activity (GO:0032312)3.33878608
30nucleosome disassembly (GO:0006337)3.33322918
31protein-DNA complex disassembly (GO:0032986)3.33322918
32peripheral nervous system neuron development (GO:0048935)3.28768533
33regulation of ARF protein signal transduction (GO:0032012)3.20249087
34DNA duplex unwinding (GO:0032508)3.19463349
35histone H3 deacetylation (GO:0070932)3.19417060
36G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.15876933
37DNA replication initiation (GO:0006270)3.08833530
38nuclear pore organization (GO:0006999)3.08790143
39histone H3-K9 modification (GO:0061647)3.08152414
40histone H3-K9 methylation (GO:0051567)3.07955018
41DNA conformation change (GO:0071103)3.06476636
42cell-cell junction maintenance (GO:0045217)3.06240076
43regulation of translational fidelity (GO:0006450)3.04621779
44regulation of histone H3-K4 methylation (GO:0051569)3.03585044
45V(D)J recombination (GO:0033151)3.01416709
46histone deubiquitination (GO:0016578)3.01115285
47histone lysine methylation (GO:0034968)3.00015763
48heterochromatin organization (GO:0070828)2.99462049
49modulation by virus of host process (GO:0019054)2.98924240
50DNA geometric change (GO:0032392)2.98649325
51regulation of DNA damage checkpoint (GO:2000001)2.98060189
52positive regulation of B cell differentiation (GO:0045579)2.94786145
53RNA stabilization (GO:0043489)2.92177618
54mRNA stabilization (GO:0048255)2.92177618
55negative regulation of myotube differentiation (GO:0010832)2.90057232
56DNA packaging (GO:0006323)2.88363296
57positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.86499396
58positive regulation of synapse maturation (GO:0090129)2.84738837
59proline biosynthetic process (GO:0006561)2.84573921
60layer formation in cerebral cortex (GO:0021819)2.83861917
61regulation of histone H3-K9 methylation (GO:0051570)2.83402897
623-UTR-mediated mRNA stabilization (GO:0070935)2.81920840
63positive regulation of CREB transcription factor activity (GO:0032793)2.81627060
64histone lysine demethylation (GO:0070076)2.81569141
65histone H3 acetylation (GO:0043966)2.81416024
66regulation of mammary gland epithelial cell proliferation (GO:0033599)2.81303862
67histone methylation (GO:0016571)2.81263085
68mitotic G1 DNA damage checkpoint (GO:0031571)2.80526418
69regulation of histone methylation (GO:0031060)2.77912112
70negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.77841325
71response to epidermal growth factor (GO:0070849)2.77741815
72mitotic sister chromatid cohesion (GO:0007064)2.77665148
73regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.76912948
74positive regulation of gamma-delta T cell activation (GO:0046645)2.76484248
75cellular response to epidermal growth factor stimulus (GO:0071364)2.73022765
76pore complex assembly (GO:0046931)2.72771181
77peptidyl-threonine phosphorylation (GO:0018107)2.71884934
78histone H3-K9 demethylation (GO:0033169)2.71639084
79protein localization to chromosome, centromeric region (GO:0071459)2.71543577
80positive regulation by host of viral transcription (GO:0043923)2.71030111
81dicarboxylic acid biosynthetic process (GO:0043650)2.70378262
82G1 DNA damage checkpoint (GO:0044783)2.69772436
83mitotic G1/S transition checkpoint (GO:0044819)2.67456315
84chromatin silencing (GO:0006342)2.66398934
85histone demethylation (GO:0016577)2.66219326
86lipid phosphorylation (GO:0046834)2.65130598
87positive regulation of granulocyte differentiation (GO:0030854)2.63865282
88neural tube development (GO:0021915)2.63397858
89negative regulation of cell size (GO:0045792)2.63322439
90spliceosomal tri-snRNP complex assembly (GO:0000244)2.63202277
91microtubule nucleation (GO:0007020)2.63080868
92positive regulation of gluconeogenesis (GO:0045722)2.61346630
93positive regulation of dendrite morphogenesis (GO:0050775)2.59414853
94cell migration in hindbrain (GO:0021535)2.59375924
95negative regulation of mRNA processing (GO:0050686)2.57976305
96negative regulation of granulocyte differentiation (GO:0030853)2.57791390
97histone phosphorylation (GO:0016572)2.57098834
98DNA strand elongation involved in DNA replication (GO:0006271)2.56399327
99regulation of mitotic spindle organization (GO:0060236)2.56125978
100DNA synthesis involved in DNA repair (GO:0000731)2.55881592

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.19397861
2VDR_21846776_ChIP-Seq_THP-1_Human3.97256073
3MYC_22102868_ChIP-Seq_BL_Human3.94314678
4FOXM1_23109430_ChIP-Seq_U2OS_Human2.82652076
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.81692726
6LXR_22292898_ChIP-Seq_THP-1_Human2.75649134
7KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.70706655
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.44859000
9TCF7_22412390_ChIP-Seq_EML_Mouse2.37042544
10KDM2B_26808549_Chip-Seq_DND41_Human2.33625037
11THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.22524964
12TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.20265998
13KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.13192347
14VDR_24763502_ChIP-Seq_THP-1_Human2.01264661
15ELK3_25401928_ChIP-Seq_HUVEC_Human2.00380047
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.93345150
17P68_20966046_ChIP-Seq_HELA_Human1.93269379
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.89166881
19KDM2B_26808549_Chip-Seq_K562_Human1.88484022
20CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.86735989
21EGR1_19374776_ChIP-ChIP_THP-1_Human1.84778283
22EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.79183708
23MAF_26560356_Chip-Seq_TH1_Human1.78270075
24MAF_26560356_Chip-Seq_TH2_Human1.76471246
25CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.74807655
26KDM2B_26808549_Chip-Seq_JURKAT_Human1.74076285
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72215198
28UTX_26944678_Chip-Seq_JUKART_Human1.71696605
29CIITA_25753668_ChIP-Seq_RAJI_Human1.65287512
30RACK7_27058665_Chip-Seq_MCF-7_Human1.64704677
31E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.64656225
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63181829
33ELF1_20517297_ChIP-Seq_JURKAT_Human1.60524510
34DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.59486488
35SCL_19346495_ChIP-Seq_HPC-7_Human1.59426031
36ZFP281_18757296_ChIP-ChIP_E14_Mouse1.59351885
37CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.59018716
38NCOR1_26117541_ChIP-Seq_K562_Human1.57630033
39SMC4_20622854_ChIP-Seq_HELA_Human1.55060487
40SA1_27219007_Chip-Seq_ERYTHROID_Human1.54758214
41CTCF_27219007_Chip-Seq_ERYTHROID_Human1.51873139
42CREB1_26743006_Chip-Seq_LNCaP_Human1.49694778
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.48868778
44CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.47938499
45EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.46585910
46PKCTHETA_26484144_Chip-Seq_BREAST_Human1.44657747
47NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.44231350
48TET1_21451524_ChIP-Seq_MESCs_Mouse1.37090384
49VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36417579
50MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.36205458
51TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.33392567
52PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.33172442
53STAT6_21828071_ChIP-Seq_BEAS2B_Human1.31626994
54ZFP281_27345836_Chip-Seq_ESCs_Mouse1.31132947
55FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.30987518
56UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.30401937
57E2F1_20622854_ChIP-Seq_HELA_Human1.29662344
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.28183040
59POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27000979
60RARB_27405468_Chip-Seq_BRAIN_Mouse1.25953034
61RUNX1_22412390_ChIP-Seq_EML_Mouse1.25251628
62CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.25024035
63XRN2_22483619_ChIP-Seq_HELA_Human1.22546566
64BCOR_27268052_Chip-Seq_Bcells_Human1.21333280
65RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20107091
66PHF8_20622854_ChIP-Seq_HELA_Human1.19826216
67CTCF_27219007_Chip-Seq_Bcells_Human1.19543794
68ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.19366030
69ESR1_15608294_ChIP-ChIP_MCF-7_Human1.17248554
70GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17046446
71BCL6_27268052_Chip-Seq_Bcells_Human1.16785836
72DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16235641
73RARA_24833708_ChIP-Seq_LIVER_Mouse1.16103644
74E2F1_21310950_ChIP-Seq_MCF-7_Human1.14722936
75SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.14619568
76SPI1_23127762_ChIP-Seq_K562_Human1.11801428
77TP53_22127205_ChIP-Seq_IMR90_Human1.10335705
78SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.09929395
79CTCF_21964334_Chip-Seq_Bcells_Human1.07531172
80ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.07203997
81TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.07012579
82GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05986045
83GATA1_19941826_ChIP-Seq_K562_Human1.05230740
84CTCF_21964334_ChIP-Seq_BJAB-B_Human1.05081174
85MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.04932385
86KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01767472
87TP63_19390658_ChIP-ChIP_HaCaT_Human1.01377596
88WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.01073835
89ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00546545
90DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.00461030
91P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00255970
92SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99922817
93TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.99516112
94ETS1_21867929_ChIP-Seq_TH2_Mouse0.99371750
95SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98393021
96RXRA_24833708_ChIP-Seq_LIVER_Mouse0.97887804
97KDM5A_27292631_Chip-Seq_BREAST_Human0.97868636
98DROSHA_22980978_ChIP-Seq_HELA_Human0.97243951
99FOXP1_21924763_ChIP-Seq_HESCs_Human0.97127115
100RARB_24833708_ChIP-Seq_LIVER_Mouse0.97085652

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology3.33338887
2MP0002396_abnormal_hematopoietic_system3.29563918
3MP0009278_abnormal_bone_marrow3.21045510
4MP0010094_abnormal_chromosome_stability3.16889061
5MP0005076_abnormal_cell_differentiation2.93309069
6MP0003172_abnormal_lysosome_physiology2.80367972
7MP0004859_abnormal_synaptic_plasticity2.78379555
8MP0003656_abnormal_erythrocyte_physiolo2.61932857
9MP0008057_abnormal_DNA_replication2.51856596
10MP0005409_darkened_coat_color2.50224436
11MP0004185_abnormal_adipocyte_glucose2.33529434
12MP0003705_abnormal_hypodermis_morpholog2.11672206
13MP0005423_abnormal_somatic_nervous2.08171211
14MP0003077_abnormal_cell_cycle2.01886340
15MP0005083_abnormal_biliary_tract1.97952736
16MP0005451_abnormal_body_composition1.96791920
17MP0005058_abnormal_lysosome_morphology1.90081350
18MP0001545_abnormal_hematopoietic_system1.80599450
19MP0005397_hematopoietic_system_phenotyp1.80599450
20MP0004808_abnormal_hematopoietic_stem1.73438165
21MP0001730_embryonic_growth_arrest1.72172675
22MP0000703_abnormal_thymus_morphology1.63963429
23MP0002822_catalepsy1.62460936
24MP0004957_abnormal_blastocyst_morpholog1.60648388
25MP0003693_abnormal_embryo_hatching1.59911572
26MP0004270_analgesia1.57685318
27MP0003123_paternal_imprinting1.55652951
28MP0005666_abnormal_adipose_tissue1.54035778
29MP0002398_abnormal_bone_marrow1.51506091
30MP0009672_abnormal_birth_weight1.48005648
31MP0000350_abnormal_cell_proliferation1.45043305
32MP0002249_abnormal_larynx_morphology1.44728956
33MP0005360_urolithiasis1.42939335
34MP0003943_abnormal_hepatobiliary_system1.30875631
35MP0002089_abnormal_postnatal_growth/wei1.29293840
36MP0000003_abnormal_adipose_tissue1.28974608
37MP0003763_abnormal_thymus_physiology1.28205083
38MP0004381_abnormal_hair_follicle1.26265398
39MP0005380_embryogenesis_phenotype1.25850319
40MP0001672_abnormal_embryogenesis/_devel1.25850319
41MP0001348_abnormal_lacrimal_gland1.20098964
42MP0001502_abnormal_circadian_rhythm1.18164810
43MP0001915_intracranial_hemorrhage1.18116754
44MP0002080_prenatal_lethality1.17624096
45MP0004197_abnormal_fetal_growth/weight/1.16284711
46MP0003635_abnormal_synaptic_transmissio1.16261909
47MP0008932_abnormal_embryonic_tissue1.16143625
48MP0003984_embryonic_growth_retardation1.15369879
49MP0005464_abnormal_platelet_physiology1.13394477
50MP0002970_abnormal_white_adipose1.12510605
51MP0008569_lethality_at_weaning1.12418029
52MP0008260_abnormal_autophagy1.10085678
53MP0005375_adipose_tissue_phenotype1.09295454
54MP0002722_abnormal_immune_system1.06100609
55MP0002928_abnormal_bile_duct1.05526097
56MP0003698_abnormal_male_reproductive1.04853564
57MP0008058_abnormal_DNA_repair1.04645242
58MP0008007_abnormal_cellular_replicative1.03432133
59MP0000313_abnormal_cell_death1.03109404
60MP0001697_abnormal_embryo_size1.02989253
61MP0002088_abnormal_embryonic_growth/wei1.01817047
62MP0002019_abnormal_tumor_incidence1.01545459
63MP0005621_abnormal_cell_physiology1.00284304
64MP0003436_decreased_susceptibility_to0.99587887
65MP0002429_abnormal_blood_cell0.97586493
66MP0003122_maternal_imprinting0.97063498
67MP0003115_abnormal_respiratory_system0.96170646
68MP0004264_abnormal_extraembryonic_tissu0.95342044
69MP0002086_abnormal_extraembryonic_tissu0.92085653
70MP0003315_abnormal_perineum_morphology0.90930327
71MP0002210_abnormal_sex_determination0.90184577
72MP0000678_abnormal_parathyroid_gland0.89965876
73MP0005365_abnormal_bile_salt0.88432412
74MP0002063_abnormal_learning/memory/cond0.87048879
75MP0002161_abnormal_fertility/fecundity0.86763042
76MP0000716_abnormal_immune_system0.86387870
77MP0001849_ear_inflammation0.86337727
78MP0005171_absent_coat_pigmentation0.85167395
79MP0003861_abnormal_nervous_system0.85145710
80MP0005384_cellular_phenotype0.84746460
81MP0001986_abnormal_taste_sensitivity0.82973462
82MP0004811_abnormal_neuron_physiology0.81911312
83MP0000689_abnormal_spleen_morphology0.81262181
84MP0003699_abnormal_female_reproductive0.79999243
85MP0001929_abnormal_gametogenesis0.77333115
86MP0008961_abnormal_basal_metabolism0.76434774
87MP0002009_preneoplasia0.75780575
88MP0002735_abnormal_chemical_nociception0.75103249
89MP0001873_stomach_inflammation0.72858683
90MP0000566_synostosis0.72832886
91MP0000685_abnormal_immune_system0.72117779
92MP0004947_skin_inflammation0.71566269
93MP0002085_abnormal_embryonic_tissue0.69567428
94MP0005220_abnormal_exocrine_pancreas0.68883317
95MP0010630_abnormal_cardiac_muscle0.67848097
96MP0009931_abnormal_skin_appearance0.67500525
97MP0002152_abnormal_brain_morphology0.66132593
98MP0000609_abnormal_liver_physiology0.66037658
99MP0002083_premature_death0.65408871
100MP0002092_abnormal_eye_morphology0.65127819

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.10193733
2Hemorrhage of the eye (HP:0011885)3.47841888
3Annular pancreas (HP:0001734)3.26704755
4Reticulocytosis (HP:0001923)3.25886167
5Broad face (HP:0000283)3.25249259
6Deep venous thrombosis (HP:0002625)3.07511825
7Hyperacusis (HP:0010780)3.06608443
8Bowel incontinence (HP:0002607)3.06456908
9Ulnar bowing (HP:0003031)2.90039382
10Metaphyseal cupping (HP:0003021)2.86910757
11Abnormal large intestine physiology (HP:0012700)2.81451761
12Flattened epiphyses (HP:0003071)2.74242312
13Heterotopia (HP:0002282)2.68851376
14Panhypogammaglobulinemia (HP:0003139)2.67247700
15Obstructive sleep apnea (HP:0002870)2.66294728
16Pointed chin (HP:0000307)2.65467979
17Abnormal gallbladder physiology (HP:0012438)2.61131183
18Cholecystitis (HP:0001082)2.61131183
19Impulsivity (HP:0100710)2.53566672
20Abnormality of reticulocytes (HP:0004312)2.53071318
21Abnormality of the columella (HP:0009929)2.50400014
22Genetic anticipation (HP:0003743)2.50091753
23Obsessive-compulsive behavior (HP:0000722)2.42547752
24Insomnia (HP:0100785)2.41895037
25Facial hemangioma (HP:0000329)2.38684281
26Self-mutilation (HP:0000742)2.34433534
27Small epiphyses (HP:0010585)2.32256147
28Slow saccadic eye movements (HP:0000514)2.29859774
29Poikiloderma (HP:0001029)2.29116926
30Urethral obstruction (HP:0000796)2.27244393
31Chromosomal breakage induced by crosslinking agents (HP:0003221)2.26978767
32Peripheral hypomyelination (HP:0007182)2.22419134
33Seborrheic dermatitis (HP:0001051)2.21013893
34Dysmetric saccades (HP:0000641)2.19645165
35Chromsome breakage (HP:0040012)2.19271856
36Long eyelashes (HP:0000527)2.18899974
37Myopathic facies (HP:0002058)2.18590480
38Broad palm (HP:0001169)2.17582741
39Increased nuchal translucency (HP:0010880)2.16501738
40Deep palmar crease (HP:0006191)2.15684321
41Abnormality of the thoracic spine (HP:0100711)2.15044378
42Intestinal fistula (HP:0100819)2.13050084
43Disproportionate tall stature (HP:0001519)2.10908319
44Basal cell carcinoma (HP:0002671)2.09643064
45Flat acetabular roof (HP:0003180)2.09022110
46Long palpebral fissure (HP:0000637)2.05989945
47Supernumerary nipples (HP:0002558)2.04892806
48Squamous cell carcinoma (HP:0002860)2.02065728
49Asymmetry of the thorax (HP:0001555)1.98739516
50Truncus arteriosus (HP:0001660)1.98609339
51Aplasia/Hypoplasia of the thymus (HP:0010515)1.95352810
52Supranuclear gaze palsy (HP:0000605)1.95348245
53Neuronal loss in central nervous system (HP:0002529)1.95182750
54Spina bifida occulta (HP:0003298)1.93306401
55Turricephaly (HP:0000262)1.91600884
56Postural instability (HP:0002172)1.91264563
57Broad distal phalanx of finger (HP:0009836)1.90926329
58Acute lymphatic leukemia (HP:0006721)1.90912073
59Attention deficit hyperactivity disorder (HP:0007018)1.90222852
60Stereotypic behavior (HP:0000733)1.88852403
61Trigonocephaly (HP:0000243)1.88593015
62Viral hepatitis (HP:0006562)1.84091672
63Cerebral aneurysm (HP:0004944)1.83292908
64Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.81915609
65Joint hemorrhage (HP:0005261)1.81269609
66Pseudobulbar signs (HP:0002200)1.80306800
67Hypoplasia of the thymus (HP:0000778)1.80302346
68Colitis (HP:0002583)1.79433945
69Abnormality of saccadic eye movements (HP:0000570)1.78558857
70High anterior hairline (HP:0009890)1.78320994
71Hypercholesterolemia (HP:0003124)1.76581985
72Anteriorly placed anus (HP:0001545)1.74518429
73Vertebral arch anomaly (HP:0008438)1.74476428
74Dislocated radial head (HP:0003083)1.74156223
75Cupped ribs (HP:0000887)1.74106338
76Chronic obstructive pulmonary disease (HP:0006510)1.74066640
77Obstructive lung disease (HP:0006536)1.74066640
78Diplopia (HP:0000651)1.70477957
79Abnormality of binocular vision (HP:0011514)1.70477957
80Ankyloglossia (HP:0010296)1.69699640
81Diaphragmatic weakness (HP:0009113)1.67788263
82Recurrent viral infections (HP:0004429)1.67369043
83Atelectasis (HP:0100750)1.66382019
84Abnormality of chromosome segregation (HP:0002916)1.66354234
85Patellar dislocation (HP:0002999)1.65027171
86Hyperthyroidism (HP:0000836)1.64859030
87Upper limb amyotrophy (HP:0009129)1.63878548
88Distal upper limb amyotrophy (HP:0007149)1.63878548
89Cholelithiasis (HP:0001081)1.63478378
90Thoracic kyphosis (HP:0002942)1.63388274
91Vaginal fistula (HP:0004320)1.63210626
92Cafe-au-lait spot (HP:0000957)1.63197917
93Abnormality of cochlea (HP:0000375)1.63172504
94Hypoparathyroidism (HP:0000829)1.63061970
95Granulocytopenia (HP:0001913)1.62868262
96Flared metaphyses (HP:0003015)1.60287075
97Embryonal neoplasm (HP:0002898)1.58250048
98Lower limb amyotrophy (HP:0007210)1.57173044
99Impaired platelet aggregation (HP:0003540)1.56240790
100Abnormal platelet function (HP:0011869)1.56240790

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.73814784
2TRIB34.04045136
3SIK23.39564105
4ICK3.26267694
5MAP3K103.18092750
6SMG12.90154075
7TNIK2.55213035
8PRPF4B2.51339437
9MAP4K12.24508612
10FGFR42.18245190
11EEF2K2.16883962
12SIK12.06455554
13ERN12.04334329
14RIPK41.99058035
15BRD41.96470476
16NEK21.66778098
17CDK41.61350274
18MARK21.55938289
19TYRO31.47198973
20NLK1.37454849
21PKN21.33811299
22KSR21.31041318
23MARK11.30912831
24MAP3K71.26290762
25BRSK11.24942498
26MAP3K61.24057301
27MTOR1.20591112
28NTRK21.15145263
29IRAK31.13067377
30RIPK11.03965712
31CDK71.00858170
32RET0.99712794
33NME10.98409817
34MAP3K130.96403737
35MAP2K30.96247711
36CDC42BPA0.93038202
37WNK10.87619222
38CHEK10.86865380
39FGFR30.84898503
40CDK90.84200186
41TESK20.83483842
42PDPK10.82776761
43CDK60.82502416
44ATR0.82367600
45WNK40.81914653
46MAPK110.80377953
47CDC70.80339386
48PDGFRA0.78514577
49BMX0.76937883
50PDK10.71176385
51BTK0.69037722
52NTRK10.67981801
53PTK2B0.65820109
54CDK10.65179690
55MAP3K90.64826786
56NTRK30.64550387
57CDK80.64336368
58CDK20.63751535
59CHEK20.62738022
60SIK30.59263673
61CAMKK10.56297813
62CLK10.55013748
63MAPK150.54063500
64CSF1R0.52416211
65CDK11A0.51694569
66CAMK1D0.51086573
67CDK150.50183611
68HIPK20.48995621
69PTK60.48937351
70PLK40.48913097
71SYK0.48769868
72GSK3B0.48569545
73TTK0.48249261
74MELK0.48218860
75RPS6KB20.47023930
76MAP3K80.46984664
77MAPK120.46660951
78BRAF0.46491058
79CDK180.43643041
80PRKD20.43579052
81MAPK80.43160796
82CAMK1G0.42266902
83RPS6KA20.41592879
84TNK20.41359436
85PASK0.40870167
86MAPK100.39856113
87FGFR20.39178813
88CDK30.37720526
89DYRK1B0.36584255
90CDK140.36222454
91PRKCH0.35862209
92UHMK10.35381282
93ITK0.33756056
94PRKD30.33608922
95MAP3K10.33339225
96CAMK40.33316116
97MAP2K40.33127100
98MAPK140.33051843
99MST1R0.32200001
100PRKAA10.31856566

Predicted pathways (KEGG)

RankGene SetZ-score
1Acute myeloid leukemia_Homo sapiens_hsa052212.45097144
2Chronic myeloid leukemia_Homo sapiens_hsa052202.34402181
3Non-small cell lung cancer_Homo sapiens_hsa052232.30275591
4DNA replication_Homo sapiens_hsa030302.25642886
5B cell receptor signaling pathway_Homo sapiens_hsa046621.99910884
6Endometrial cancer_Homo sapiens_hsa052131.80749604
7Thyroid cancer_Homo sapiens_hsa052161.79354056
8Lysine degradation_Homo sapiens_hsa003101.79251533
9Glioma_Homo sapiens_hsa052141.78865169
10VEGF signaling pathway_Homo sapiens_hsa043701.73916259
11Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.69906949
12Colorectal cancer_Homo sapiens_hsa052101.69762364
13Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.68999198
14Phosphatidylinositol signaling system_Homo sapiens_hsa040701.66220202
15Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.64250080
16mTOR signaling pathway_Homo sapiens_hsa041501.60434448
17Pancreatic cancer_Homo sapiens_hsa052121.59594675
18ErbB signaling pathway_Homo sapiens_hsa040121.54634430
19Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.50794419
20Cell cycle_Homo sapiens_hsa041101.47057480
21Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.43584267
22mRNA surveillance pathway_Homo sapiens_hsa030151.41935269
23Base excision repair_Homo sapiens_hsa034101.40876025
24Inositol phosphate metabolism_Homo sapiens_hsa005621.39526054
25Central carbon metabolism in cancer_Homo sapiens_hsa052301.38082705
26Neurotrophin signaling pathway_Homo sapiens_hsa047221.38014064
27Thyroid hormone signaling pathway_Homo sapiens_hsa049191.34916868
28Long-term potentiation_Homo sapiens_hsa047201.34112052
29Notch signaling pathway_Homo sapiens_hsa043301.29934189
30Choline metabolism in cancer_Homo sapiens_hsa052311.26022453
31Renal cell carcinoma_Homo sapiens_hsa052111.25590751
32Fructose and mannose metabolism_Homo sapiens_hsa000511.23539872
33Prostate cancer_Homo sapiens_hsa052151.22683362
34Type II diabetes mellitus_Homo sapiens_hsa049301.18351356
35Cyanoamino acid metabolism_Homo sapiens_hsa004601.16158197
36Prion diseases_Homo sapiens_hsa050201.11140693
37Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.10565141
38Bladder cancer_Homo sapiens_hsa052191.09166481
39Estrogen signaling pathway_Homo sapiens_hsa049151.08799258
40Other glycan degradation_Homo sapiens_hsa005111.06712725
41T cell receptor signaling pathway_Homo sapiens_hsa046601.06633666
42Carbohydrate digestion and absorption_Homo sapiens_hsa049731.05905208
43Insulin signaling pathway_Homo sapiens_hsa049101.03075797
44Mismatch repair_Homo sapiens_hsa034301.02766813
45Phospholipase D signaling pathway_Homo sapiens_hsa040721.02701555
46Hepatitis B_Homo sapiens_hsa051611.01319831
47Prolactin signaling pathway_Homo sapiens_hsa049170.98802926
48Primary immunodeficiency_Homo sapiens_hsa053400.96085178
49GnRH signaling pathway_Homo sapiens_hsa049120.90797304
50Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.90604978
51MicroRNAs in cancer_Homo sapiens_hsa052060.88843947
52AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.86528336
53Longevity regulating pathway - mammal_Homo sapiens_hsa042110.84806046
54Fanconi anemia pathway_Homo sapiens_hsa034600.83870731
55Sulfur relay system_Homo sapiens_hsa041220.82919181
56Influenza A_Homo sapiens_hsa051640.80975235
57Cholinergic synapse_Homo sapiens_hsa047250.78189296
58Biosynthesis of amino acids_Homo sapiens_hsa012300.78159894
59Spliceosome_Homo sapiens_hsa030400.78022466
60Oocyte meiosis_Homo sapiens_hsa041140.75881532
61HTLV-I infection_Homo sapiens_hsa051660.74086359
62AMPK signaling pathway_Homo sapiens_hsa041520.72717873
63Sphingolipid signaling pathway_Homo sapiens_hsa040710.72420923
64HIF-1 signaling pathway_Homo sapiens_hsa040660.71413473
65Epstein-Barr virus infection_Homo sapiens_hsa051690.68138303
66Glycerophospholipid metabolism_Homo sapiens_hsa005640.63746402
67Viral carcinogenesis_Homo sapiens_hsa052030.62978698
68MAPK signaling pathway_Homo sapiens_hsa040100.59793618
69Aldosterone synthesis and secretion_Homo sapiens_hsa049250.59695580
70Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.58539612
71Herpes simplex infection_Homo sapiens_hsa051680.58460910
72Insulin resistance_Homo sapiens_hsa049310.57924992
73Melanogenesis_Homo sapiens_hsa049160.56942387
74Nicotine addiction_Homo sapiens_hsa050330.56909063
75RNA transport_Homo sapiens_hsa030130.56322057
76Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.56013963
77Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55504142
78Hepatitis C_Homo sapiens_hsa051600.55222197
79Apoptosis_Homo sapiens_hsa042100.55143636
80FoxO signaling pathway_Homo sapiens_hsa040680.52877917
81Osteoclast differentiation_Homo sapiens_hsa043800.52140908
82Adipocytokine signaling pathway_Homo sapiens_hsa049200.52036481
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52032362
84Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.51478871
85Adherens junction_Homo sapiens_hsa045200.51312965
86Toll-like receptor signaling pathway_Homo sapiens_hsa046200.48420257
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.47742304
88Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.46518622
89Thyroid hormone synthesis_Homo sapiens_hsa049180.46463621
90Measles_Homo sapiens_hsa051620.46433249
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45663446
92Glucagon signaling pathway_Homo sapiens_hsa049220.45252233
93Platelet activation_Homo sapiens_hsa046110.44196577
94Axon guidance_Homo sapiens_hsa043600.43364022
95Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.39969112
96Endocytosis_Homo sapiens_hsa041440.39743709
97Leishmaniasis_Homo sapiens_hsa051400.39469938
98Homologous recombination_Homo sapiens_hsa034400.39437052
99Fatty acid biosynthesis_Homo sapiens_hsa000610.39145909
100Wnt signaling pathway_Homo sapiens_hsa043100.38858182

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »