LIPM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1multicellular organismal water homeostasis (GO:0050891)8.37109420
2keratinocyte differentiation (GO:0030216)7.75600531
3keratinocyte proliferation (GO:0043616)7.47752595
4water homeostasis (GO:0030104)6.96459078
5sphingoid metabolic process (GO:0046519)6.94124053
6hair cycle (GO:0042633)6.40951743
7molting cycle (GO:0042303)6.40951743
8positive regulation of cellular amide metabolic process (GO:0034250)6.36884709
9sphingosine metabolic process (GO:0006670)6.30878327
10epidermal cell differentiation (GO:0009913)6.13311376
11long-chain fatty acid biosynthetic process (GO:0042759)5.92807986
12peptide cross-linking (GO:0018149)5.80593740
13regulation of cell proliferation involved in kidney development (GO:1901722)5.77898079
14hemidesmosome assembly (GO:0031581)5.65744591
15diol metabolic process (GO:0034311)5.60996823
16regulation of ruffle assembly (GO:1900027)5.50849872
17positive regulation of interleukin-8 secretion (GO:2000484)5.48328000
18regulation of transforming growth factor beta1 production (GO:0032908)5.40369001
19bundle of His cell to Purkinje myocyte communication (GO:0086069)5.18345884
20regulation of phospholipase A2 activity (GO:0032429)5.10209092
21epidermis development (GO:0008544)5.07696239
22glucosamine-containing compound catabolic process (GO:1901072)5.06664778
23positive regulation of glomerulus development (GO:0090193)5.01609923
24detection of bacterium (GO:0016045)4.87067553
25intermediate filament organization (GO:0045109)4.79262655
26interferon-gamma secretion (GO:0072643)4.73513444
27positive regulation of humoral immune response (GO:0002922)4.71550345
28viral transcription (GO:0019083)4.70890652
29G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.61202314
30regulation of hypersensitivity (GO:0002883)4.53303460
31keratinocyte development (GO:0003334)4.49785679
32fatty acid elongation (GO:0030497)4.48497533
33translational termination (GO:0006415)4.40059817
34detection of external biotic stimulus (GO:0098581)4.32312723
35linoleic acid metabolic process (GO:0043651)4.29898135
36negative regulation of interleukin-17 production (GO:0032700)4.23335087
37regulation of interleukin-8 secretion (GO:2000482)4.22269567
38positive regulation of T-helper 1 type immune response (GO:0002827)4.21746680
39ribosomal small subunit biogenesis (GO:0042274)4.18877388
40regulation of chemokine secretion (GO:0090196)4.15645192
41lipoxygenase pathway (GO:0019372)4.15223727
42detection of other organism (GO:0098543)4.14173317
43chemical homeostasis within a tissue (GO:0048875)4.05459328
44defense response to fungus (GO:0050832)3.99688398
45skin morphogenesis (GO:0043589)3.98033450
46surfactant homeostasis (GO:0043129)3.67726555
47cyclooxygenase pathway (GO:0019371)3.67616103
48detection of biotic stimulus (GO:0009595)3.66917974
49defense response to Gram-negative bacterium (GO:0050829)3.65879837
50ectoderm development (GO:0007398)3.65201504
51negative regulation of interferon-gamma production (GO:0032689)3.65199723
52phosphatidylinositol acyl-chain remodeling (GO:0036149)3.62044061
53negative regulation of T cell mediated immunity (GO:0002710)3.59462069
54prostanoid biosynthetic process (GO:0046457)3.51993739
55prostaglandin biosynthetic process (GO:0001516)3.51993739
56regulation of T-helper 1 type immune response (GO:0002825)3.51840161
57SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.47142552
58viral life cycle (GO:0019058)3.46215747
59translational elongation (GO:0006414)3.45776173
60protein targeting to ER (GO:0045047)3.42960500
61phosphatidylcholine acyl-chain remodeling (GO:0036151)3.42239736
62cotranslational protein targeting to membrane (GO:0006613)3.40239220
63negative regulation of interleukin-2 production (GO:0032703)3.39487991
64regulation of glomerulus development (GO:0090192)3.39132872
65eyelid development in camera-type eye (GO:0061029)3.37886985
66negative regulation of acute inflammatory response (GO:0002674)3.35853949
67establishment of protein localization to endoplasmic reticulum (GO:0072599)3.34960506
68phospholipid efflux (GO:0033700)3.32044013
69positive regulation of cholesterol efflux (GO:0010875)3.31669358
70regulation of cellular amide metabolic process (GO:0034248)3.31482750
71cellular protein complex disassembly (GO:0043624)3.30003878
72positive regulation of chemokine secretion (GO:0090197)3.27206197
73response to fungus (GO:0009620)3.27176874
74negative regulation of stress fiber assembly (GO:0051497)3.25085757
75regulation of interleukin-17 production (GO:0032660)3.23530497
76positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.23472478
77phosphatidylserine acyl-chain remodeling (GO:0036150)3.23372438
78phospholipid scrambling (GO:0017121)3.22729379
79long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.20638899
80response to peptidoglycan (GO:0032494)3.20108510
81protein localization to endoplasmic reticulum (GO:0070972)3.16756550
82cardiac right ventricle morphogenesis (GO:0003215)3.15761621
83positive regulation of type 2 immune response (GO:0002830)3.15611319
84positive regulation of interleukin-4 production (GO:0032753)3.15411533
85positive regulation of vesicle fusion (GO:0031340)3.13992087
86natural killer cell activation involved in immune response (GO:0002323)3.12953961
87dendritic cell migration (GO:0036336)3.10628100
88branching involved in labyrinthine layer morphogenesis (GO:0060670)3.10160173
89phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.10100741
90nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.10058847
91positive regulation of interleukin-6 production (GO:0032755)3.09762053
92modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.07553336
93positive regulation by organism of defense response of other organism involved in symbiotic interact3.07553336
94modulation by symbiont of host immune response (GO:0052553)3.07553336
95positive regulation by symbiont of host defense response (GO:0052509)3.07553336
96modulation by symbiont of host defense response (GO:0052031)3.07553336
97modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.07553336
98regulation of T-helper 1 cell differentiation (GO:0045625)3.06425153
99glutathione biosynthetic process (GO:0006750)3.02331356
100phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.00640771
101positive regulation of sterol transport (GO:0032373)2.99407640
102positive regulation of cholesterol transport (GO:0032376)2.99407640
103regulation of natural killer cell differentiation (GO:0032823)2.97963658
104production of molecular mediator involved in inflammatory response (GO:0002532)2.97185866
105detection of molecule of bacterial origin (GO:0032490)2.96543735
106maturation of SSU-rRNA (GO:0030490)2.96185912
107regulation of acute inflammatory response to antigenic stimulus (GO:0002864)2.95999319
108positive regulation of p38MAPK cascade (GO:1900745)2.95791222
109macrophage activation involved in immune response (GO:0002281)2.95198361
110negative regulation of kidney development (GO:0090185)2.94603348
111intermediate filament cytoskeleton organization (GO:0045104)2.90174088
112establishment of tissue polarity (GO:0007164)2.89361150
113establishment of planar polarity (GO:0001736)2.89361150
114positive regulation of monocyte chemotaxis (GO:0090026)2.89015661
115prostaglandin metabolic process (GO:0006693)2.88912754
116prostanoid metabolic process (GO:0006692)2.88912754
117negative regulation of keratinocyte proliferation (GO:0010839)2.88268279
118negative regulation of interleukin-12 production (GO:0032695)2.87963767
119regulation of monocyte chemotaxis (GO:0090025)2.86996604
120icosanoid secretion (GO:0032309)2.86583628
121arachidonic acid secretion (GO:0050482)2.86583628
122gland morphogenesis (GO:0022612)2.85322028
123intermediate filament-based process (GO:0045103)2.85107547
124retinal metabolic process (GO:0042574)2.84247480
125unsaturated fatty acid biosynthetic process (GO:0006636)2.79206960
126cardiolipin metabolic process (GO:0032048)2.77576306
127planar cell polarity pathway involved in neural tube closure (GO:0090179)2.77285769
128nonribosomal peptide biosynthetic process (GO:0019184)2.77054965
129primary alcohol catabolic process (GO:0034310)2.76764148
130T-helper 1 type immune response (GO:0042088)2.76755176
131negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.76291587
132neutrophil activation involved in immune response (GO:0002283)2.74572919
133regulation of dendritic cell antigen processing and presentation (GO:0002604)2.72343521
134regulation of interleukin-6 production (GO:0032675)2.70645839
135positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)2.70523271
136regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)2.70523271
137epithelial cell differentiation involved in prostate gland development (GO:0060742)2.68634486
138interferon-gamma-mediated signaling pathway (GO:0060333)2.66010116
139type I interferon signaling pathway (GO:0060337)2.65440099
140cellular response to type I interferon (GO:0071357)2.65440099
141phosphatidylserine metabolic process (GO:0006658)2.61498245
142regulation of MHC class I biosynthetic process (GO:0045343)2.61085140
143response to type I interferon (GO:0034340)2.59544738
144negative regulation of vascular permeability (GO:0043116)2.59334818
145immunoglobulin mediated immune response (GO:0016064)2.59175058
146positive regulation of Cdc42 GTPase activity (GO:0043089)2.58206696
147somite development (GO:0061053)2.54261990
148antimicrobial humoral response (GO:0019730)2.52296201
149regulation of natural killer cell activation (GO:0032814)2.50761025
150ceramide biosynthetic process (GO:0046513)2.50316824
151response to muramyl dipeptide (GO:0032495)2.48592383
152positive regulation of gamma-delta T cell activation (GO:0046645)2.46761007
153regulation of type 2 immune response (GO:0002828)2.46180803
154negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.44445667
155positive regulation of antigen processing and presentation (GO:0002579)2.42792653
156defense response to Gram-positive bacterium (GO:0050830)2.42751154
157desmosome organization (GO:0002934)14.4847067
158establishment of skin barrier (GO:0061436)13.8044122
159regulation of water loss via skin (GO:0033561)12.3421657
160keratinization (GO:0031424)11.1678370

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse6.23190164
2IRF8_21731497_ChIP-ChIP_J774_Mouse3.33398983
3* P63_26484246_Chip-Seq_KERATINOCYTES_Human3.23602563
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.05324273
5SOX9_24532713_ChIP-Seq_HFSC_Mouse2.94434037
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.70264956
7ESR1_21235772_ChIP-Seq_MCF-7_Human2.60450007
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.55673398
9SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.38845102
10SMAD_19615063_ChIP-ChIP_OVARY_Human2.28340770
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.26908912
12ESR2_21235772_ChIP-Seq_MCF-7_Human2.17345340
13BP1_19119308_ChIP-ChIP_Hs578T_Human2.12163270
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.11127295
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.09049536
16TP63_17297297_ChIP-ChIP_HaCaT_Human15.1983239
17FOXO3_23340844_ChIP-Seq_DLD1_Human1.94460853
18SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.94161322
19SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.94161322
20ZNF263_19887448_ChIP-Seq_K562_Human1.93699272
21Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.89948071
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.89687599
23ESR1_20079471_ChIP-ChIP_T-47D_Human1.87198330
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.84833031
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81552915
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.78562613
27MYB_21317192_ChIP-Seq_ERMYB_Mouse1.77109538
28ZNF217_24962896_ChIP-Seq_MCF-7_Human1.71541210
29STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.69189157
30NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.66464934
31GATA1_22025678_ChIP-Seq_K562_Human1.65646612
32IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.57759453
33TCF4_18268006_ChIP-ChIP_LS174T_Human1.54906635
34SOX2_20726797_ChIP-Seq_SW620_Human1.53421384
35TP63_23658742_ChIP-Seq_EP156T_Human1.51161404
36ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.49270509
37EGR1_19032775_ChIP-ChIP_M12_Human1.46938599
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.38580902
39CJUN_26792858_Chip-Seq_BT549_Human1.37262794
40RUNX_20019798_ChIP-Seq_JUKART_Human1.35280405
41BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.33115697
42TP53_18474530_ChIP-ChIP_U2OS_Human1.30940429
43TP63_22573176_ChIP-Seq_HFKS_Human1.29834273
44RUNX1_27514584_Chip-Seq_MCF-7_Human1.29341677
45GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.27980129
46KLF5_25053715_ChIP-Seq_YYC3_Human1.26180921
47MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.25837117
48RXR_22108803_ChIP-Seq_LS180_Human1.19834656
49VDR_22108803_ChIP-Seq_LS180_Human1.18656200
50TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.18644481
51AR_21572438_ChIP-Seq_LNCaP_Human1.18432914
52VDR_24787735_ChIP-Seq_THP-1_Human1.16483768
53BCAT_22108803_ChIP-Seq_LS180_Human1.14011626
54STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.13495048
55KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.12572643
56GATA6_21074721_ChIP-Seq_CACO-2_Human1.10629829
57SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10427089
58CEBPB_22108803_ChIP-Seq_LS180_Human1.10378894
59AHR_22903824_ChIP-Seq_MCF-7_Human1.10207194
60HIF1A_21447827_ChIP-Seq_MCF-7_Human1.08500359
61GATA3_24758297_ChIP-Seq_MCF-7_Human1.08123274
62BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.06372057
63* GATA4_25053715_ChIP-Seq_YYC3_Human1.03311565
64RARG_19884340_ChIP-ChIP_MEFs_Mouse1.03040604
65VDR_24763502_ChIP-Seq_THP-1_Human1.01955892
66ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01645682
67TP53_20018659_ChIP-ChIP_R1E_Mouse1.00980267
68STAT4_19710469_ChIP-ChIP_TH1__Mouse1.00093202
69FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.97283235
70ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.97037148
71TP53_16413492_ChIP-PET_HCT116_Human0.96391343
72BRD4_27068464_Chip-Seq_AML-cells_Mouse0.95365399
73UBF1/2_26484160_Chip-Seq_HMECs_Human0.95079309
74ATF3_27146783_Chip-Seq_COLON_Human0.94408194
75KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.92541187
76SUZ12_27294783_Chip-Seq_ESCs_Mouse0.92540545
77PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91099193
78FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.90572687
79RACK7_27058665_Chip-Seq_MCF-7_Human0.88701317
80FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.87539241
81PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85085392
82CDX2_20551321_ChIP-Seq_CACO-2_Human0.84223104
83CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.84107908
84BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.83956484
85TCF4_22108803_ChIP-Seq_LS180_Human0.83757925
86FOXM1_26456572_ChIP-Seq_MCF-7_Human0.82932967
87ARNT_22903824_ChIP-Seq_MCF-7_Human0.81339785
88CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.81024833
89ERG_20517297_ChIP-Seq_VCAP_Human0.80704996
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.79683117
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79683117
92STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.78891519
93GATA6_25053715_ChIP-Seq_YYC3_Human0.78678785
94CTCF_27219007_Chip-Seq_Bcells_Human0.78278106
95NRF2_20460467_ChIP-Seq_MEFs_Mouse0.77885683
96NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.77885683
97GATA1_19941827_ChIP-Seq_MEL86_Mouse0.77876920
98RBPJ_21746931_ChIP-Seq_IB4_Human0.77607009
99EED_16625203_ChIP-ChIP_MESCs_Mouse0.77585600
100VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.77490338
101NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.77139558
102KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.76909257
103KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.76909257
104KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.76909257
105EZH2_27304074_Chip-Seq_ESCs_Mouse0.76876486
106BMI1_23680149_ChIP-Seq_NPCS_Mouse0.76566206
107JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76028884
108CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.76023126
109UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.75095366
110SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.74957544
111LXR_22158963_ChIP-Seq_LIVER_Mouse0.74378588
112CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.74118087
113PU_27001747_Chip-Seq_BMDM_Mouse0.74086182
114SOX2_27498859_Chip-Seq_STOMACH_Mouse0.73767753
115P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.73131442
116FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.72291111
117GATA3_21867929_ChIP-Seq_TH1_Mouse0.71917783
118PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.71632927
119SA1_27219007_Chip-Seq_ERYTHROID_Human0.71340146
120EZH2_27294783_Chip-Seq_ESCs_Mouse0.71163285
121GATA3_26560356_Chip-Seq_TH2_Human0.70632614
122HNFA_21074721_ChIP-Seq_CACO-2_Human0.70571524
123RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.70023545
124MYB_26560356_Chip-Seq_TH1_Human0.69673450
125PPAR_26484153_Chip-Seq_NCI-H1993_Human0.68673037
126FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.67329639
127DNAJC2_21179169_ChIP-ChIP_NT2_Human0.67211458
128LXR_22292898_ChIP-Seq_THP-1_Human0.66946622
129JARID2_20075857_ChIP-Seq_MESCs_Mouse0.66464334
130SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.66107835
131YY1_22570637_ChIP-Seq_MALME-3M_Human0.65030748
132SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.64921734
133JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.64637721
134SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.63718644
135CDX2_19796622_ChIP-Seq_MESCs_Mouse0.63223610
136RNF2_27304074_Chip-Seq_ESCs_Mouse0.62570738
137SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.61508750
138BCOR_27268052_Chip-Seq_Bcells_Human0.60280621
139NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.59840264
140SA1_27219007_Chip-Seq_Bcells_Human0.57789868
141PHF8_20622853_ChIP-Seq_HELA_Human0.57203627
142KDM2B_26808549_Chip-Seq_K562_Human0.56728223
143CSB_26484114_Chip-Seq_FIBROBLAST_Human0.56633396
144GATA2_21666600_ChIP-Seq_HMVEC_Human0.56007748
145FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.55606751

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier8.26833574
2MP0003941_abnormal_skin_development6.03445048
3MP0010234_abnormal_vibrissa_follicle5.63827671
4MP0005275_abnormal_skin_tensile5.53666991
5MP0005501_abnormal_skin_physiology4.98916537
6MP0004381_abnormal_hair_follicle4.03696605
7MP0002060_abnormal_skin_morphology3.69449792
8MP0005451_abnormal_body_composition3.64311107
9MP0002254_reproductive_system_inflammat3.63866570
10MP0001216_abnormal_epidermal_layer3.48473099
11MP0010771_integument_phenotype3.18929771
12MP0010678_abnormal_skin_adnexa2.99185400
13MP0003453_abnormal_keratinocyte_physiol2.96333576
14MP0000383_abnormal_hair_follicle2.92117602
15MP0004947_skin_inflammation2.91208105
16MP0002098_abnormal_vibrissa_morphology2.90577808
17MP0000647_abnormal_sebaceous_gland2.71955779
18MP0000579_abnormal_nail_morphology2.70707911
19MP0003724_increased_susceptibility_to2.66201333
20MP0000377_abnormal_hair_follicle2.22071323
21MP0000467_abnormal_esophagus_morphology2.02877040
22MP0000427_abnormal_hair_cycle1.94712624
23MP0002009_preneoplasia1.89208144
24MP0009379_abnormal_foot_pigmentation1.85312349
25MP0009931_abnormal_skin_appearance1.80929468
26MP0000566_synostosis1.80649671
27MP0004185_abnormal_adipocyte_glucose1.78341376
28MP0000015_abnormal_ear_pigmentation1.75621363
29MP0001346_abnormal_lacrimal_gland1.73863064
30MP0001191_abnormal_skin_condition1.72994501
31MP0003191_abnormal_cellular_cholesterol1.72914514
32MP0003303_peritoneal_inflammation1.69781343
33MP0003705_abnormal_hypodermis_morpholog1.54289791
34MP0009785_altered_susceptibility_to1.51008594
35MP0003566_abnormal_cell_adhesion1.48164301
36MP0001835_abnormal_antigen_presentation1.47740629
37MP0004782_abnormal_surfactant_physiolog1.44687558
38MP0001188_hyperpigmentation1.44090200
39MP0000569_abnormal_digit_pigmentation1.41752009
40MP0000367_abnormal_coat/_hair1.40950968
41MP0001243_abnormal_dermal_layer1.39513820
42MP0005174_abnormal_tail_pigmentation1.38487767
43MP0000762_abnormal_tongue_morphology1.38258057
44MP0001851_eye_inflammation1.34560183
45MP0006082_CNS_inflammation1.30526276
46MP0005025_abnormal_response_to1.28288421
47MP0001800_abnormal_humoral_immune1.18940469
48MP0005000_abnormal_immune_tolerance1.16489370
49MP0001790_abnormal_immune_system1.12659355
50MP0005387_immune_system_phenotype1.12659355
51MP0002419_abnormal_innate_immunity1.10236983
52MP0002723_abnormal_immune_serum1.04587955
53MP0001340_abnormal_eyelid_morphology1.03799568
54MP0005671_abnormal_response_to1.03318857
55MP0004510_myositis1.01424988
56MP0003136_yellow_coat_color1.01346094
57MP0003300_gastrointestinal_ulcer0.99722309
58MP0002452_abnormal_antigen_presenting0.99567220
59MP0008260_abnormal_autophagy0.99233559
60MP0010352_gastrointestinal_tract_polyps0.98552524
61MP0003656_abnormal_erythrocyte_physiolo0.96476250
62MP0003878_abnormal_ear_physiology0.92166356
63MP0005377_hearing/vestibular/ear_phenot0.92166356
64MP0003011_delayed_dark_adaptation0.89102614
65MP0001533_abnormal_skeleton_physiology0.87173105
66MP0008004_abnormal_stomach_pH0.86126824
67MP0009840_abnormal_foam_cell0.85757834
68MP0002006_tumorigenesis0.82466998
69MP0010155_abnormal_intestine_physiology0.81780626
70MP0009333_abnormal_splenocyte_physiolog0.81702458
71MP0000465_gastrointestinal_hemorrhage0.79968072
72MP0001819_abnormal_immune_cell0.79769104
73MP0002138_abnormal_hepatobiliary_system0.79501677
74MP0002420_abnormal_adaptive_immunity0.79099512
75MP0004885_abnormal_endolymph0.78102942
76MP0009765_abnormal_xenobiotic_induced0.77774183
77MP0003221_abnormal_cardiomyocyte_apopto0.73470239
78MP0002877_abnormal_melanocyte_morpholog0.72858592
79MP0003828_pulmonary_edema0.71103645
80MP0005023_abnormal_wound_healing0.70368388
81MP0000627_abnormal_mammary_gland0.69273586
82MP0002277_abnormal_respiratory_mucosa0.68043980
83MP0001845_abnormal_inflammatory_respons0.67108559
84MP0000604_amyloidosis0.65870627
85MP0002177_abnormal_outer_ear0.64599152
86MP0005076_abnormal_cell_differentiation0.63668750
87MP0002166_altered_tumor_susceptibility0.63286596
88MP0002998_abnormal_bone_remodeling0.63126956
89MP0002405_respiratory_system_inflammati0.59933053
90MP0001853_heart_inflammation0.59839416
91MP0003329_amyloid_beta_deposits0.59061504
92MP0005310_abnormal_salivary_gland0.58912167
93MP0002148_abnormal_hypersensitivity_rea0.57440010
94MP0003448_altered_tumor_morphology0.57258761
95MP0002234_abnormal_pharynx_morphology0.56378422
96MP0001784_abnormal_fluid_regulation0.56219067
97MP0009384_cardiac_valve_regurgitation0.55134969
98MP0005058_abnormal_lysosome_morphology0.54685920
99MP0003075_altered_response_to0.54079698
100MP0003763_abnormal_thymus_physiology0.52901813
101MP0002095_abnormal_skin_pigmentation0.52092031
102MP0003950_abnormal_plasma_membrane0.52031229
103MP0001984_abnormal_olfaction0.51918264
104MP0008961_abnormal_basal_metabolism0.51719482
105MP0001324_abnormal_eye_pigmentation0.51542053
106MP0003436_decreased_susceptibility_to0.51470464
107MP0003315_abnormal_perineum_morphology0.50679769
108MP0009053_abnormal_anal_canal0.50411064
109MP0009764_decreased_sensitivity_to0.50328211
110MP0004019_abnormal_vitamin_homeostasis0.49700889
111MP0008469_abnormal_protein_level0.48372172
112MP0005666_abnormal_adipose_tissue0.47039233
113MP0006054_spinal_hemorrhage0.45043731
114MP0005075_abnormal_melanosome_morpholog0.44443757
115MP0005367_renal/urinary_system_phenotyp0.43448006
116MP0000516_abnormal_urinary_system0.43448006
117MP0003638_abnormal_response/metabolism_0.42997489
118MP0005647_abnormal_sex_gland0.39879853
119MP0000470_abnormal_stomach_morphology0.39771093
120MP0001177_atelectasis0.37778794
121MP0005187_abnormal_penis_morphology0.37459996
122MP0002249_abnormal_larynx_morphology0.36749189
123MP0001849_ear_inflammation0.35213539
124MP0005508_abnormal_skeleton_morphology0.34680579
125MP0010030_abnormal_orbit_morphology0.33912417
126MP0000538_abnormal_urinary_bladder0.31918774
127MP0005375_adipose_tissue_phenotype0.31800325
128MP0002282_abnormal_trachea_morphology0.31350007
129MP0003755_abnormal_palate_morphology0.29423503
130MP0004264_abnormal_extraembryonic_tissu0.28260197
131MP0003183_abnormal_peptide_metabolism0.28129912
132MP0000750_abnormal_muscle_regeneration0.27649148
133MP0001873_stomach_inflammation0.26063256
134MP0002090_abnormal_vision0.25988212
135MP0003938_abnormal_ear_development0.24713027
136MP0000613_abnormal_salivary_gland0.24619917
137MP0002111_abnormal_tail_morphology0.24528945
138MP0000432_abnormal_head_morphology0.23499589
139MP0002132_abnormal_respiratory_system0.22630088
140MP0005409_darkened_coat_color0.22597729
141MP0001666_abnormal_nutrient_absorption0.22363960
142MP0004272_abnormal_basement_membrane0.22000584
143MP0000372_irregular_coat_pigmentation0.21814234
144MP0005390_skeleton_phenotype0.19342911
145MP0002971_abnormal_brown_adipose0.18321124
146MP0000537_abnormal_urethra_morphology0.18181326
147MP0000858_altered_metastatic_potential0.15131897
148MP0000685_abnormal_immune_system0.14480634

Predicted human phenotypes

RankGene SetZ-score
1Congenital ichthyosiform erythroderma (HP:0007431)8.36981468
2Congenital nonbullous ichthyosiform erythroderma (HP:0007479)8.03622784
3Hypotrichosis (HP:0001006)7.44625347
4Increased IgE level (HP:0003212)6.51260616
5Parakeratosis (HP:0001036)6.10593285
6Woolly hair (HP:0002224)6.09987146
7Lip pit (HP:0100267)6.09215706
8Right ventricular cardiomyopathy (HP:0011663)5.78701073
9Plantar hyperkeratosis (HP:0007556)5.74714937
10Abnormality of nail color (HP:0100643)5.67371146
11Palmoplantar hyperkeratosis (HP:0000972)5.57824113
12Erythema (HP:0010783)5.48624015
13Erythroderma (HP:0001019)5.33041861
14Palmar hyperkeratosis (HP:0010765)5.22698926
15Gangrene (HP:0100758)4.87057147
16Onycholysis (HP:0001806)4.79056839
17Fragile nails (HP:0001808)4.75567253
18Ectropion (HP:0000656)4.73180215
19Oral leukoplakia (HP:0002745)4.59750159
20Corneal erosion (HP:0200020)4.28972107
21Abnormality of the axillary hair (HP:0100134)4.15239799
22Abnormality of secondary sexual hair (HP:0009888)4.15239799
23Conjunctival hamartoma (HP:0100780)4.11757300
24Hyporeflexia of lower limbs (HP:0002600)4.04878636
25Hypohidrosis (HP:0000966)3.98851543
26Pruritus (HP:0000989)3.70570210
27Curly hair (HP:0002212)3.69864245
28Abnormal blistering of the skin (HP:0008066)3.62359398
29Pili torti (HP:0003777)3.60951783
30Milia (HP:0001056)3.48252172
31Palmoplantar keratoderma (HP:0000982)3.37159855
32Distal lower limb muscle weakness (HP:0009053)3.35299018
33Sparse scalp hair (HP:0002209)3.32374442
34Areflexia of lower limbs (HP:0002522)3.31252991
35Nail dystrophy (HP:0008404)3.23257879
36Natal tooth (HP:0000695)3.20910559
37Sparse eyelashes (HP:0000653)3.20423478
38Popliteal pterygium (HP:0009756)3.20243329
39Ventricular tachycardia (HP:0004756)3.13777000
40Thick nail (HP:0001805)3.13700888
41Recurrent bacterial skin infections (HP:0005406)2.98297449
42Acanthosis nigricans (HP:0000956)2.91552785
43Advanced eruption of teeth (HP:0006288)2.88291786
44Abnormality of cells of the erythroid lineage (HP:0012130)2.77851941
45Concave nail (HP:0001598)2.74930435
46Lack of skin elasticity (HP:0100679)2.74874555
47Urticaria (HP:0001025)2.73882172
48Recurrent skin infections (HP:0001581)2.71354085
49Keratoconjunctivitis sicca (HP:0001097)2.64640911
50Abnormality of the salivary glands (HP:0010286)2.56880188
51Brittle hair (HP:0002299)2.56837683
52Congenital, generalized hypertrichosis (HP:0004540)2.55113924
53Orchitis (HP:0100796)2.54051943
54Retrobulbar optic neuritis (HP:0100654)2.53862337
55Optic neuritis (HP:0100653)2.53862337
56Dry skin (HP:0000958)2.51907264
57Aplasia cutis congenita (HP:0001057)2.51824340
58Reticulocytopenia (HP:0001896)2.51204438
59Abnormal hemoglobin (HP:0011902)2.50704615
60Dehydration (HP:0001944)2.49144518
61Abnormality of macrophages (HP:0004311)2.42532527
62Hypoplastic labia majora (HP:0000059)2.41654792
63Malignant hyperthermia (HP:0002047)2.41368039
64Keratoconjunctivitis (HP:0001096)2.36596892
65Oligodontia (HP:0000677)2.33124932
66Abnormal hair laboratory examination (HP:0003328)2.30823194
67Abnormal number of erythroid precursors (HP:0012131)2.30226942
68Follicular hyperkeratosis (HP:0007502)2.29151614
69Anhidrosis (HP:0000970)2.26663503
70Atrophic scars (HP:0001075)2.24214934
71Hamartoma of the eye (HP:0010568)2.22939927
72Eczematoid dermatitis (HP:0000976)2.20165665
73Myositis (HP:0100614)2.19297464
74Abnormality of the labia majora (HP:0012881)2.18080017
75Abnormality of the gastric mucosa (HP:0004295)2.13933941
76Severe Myopia (HP:0011003)2.12532986
77Absent eyelashes (HP:0000561)2.09705082
78Furrowed tongue (HP:0000221)2.06639401
79Stenosis of the external auditory canal (HP:0000402)2.05709661
80Amniotic constriction ring (HP:0009775)2.05562306
81Abnormality of placental membranes (HP:0011409)2.05562306
82Xerostomia (HP:0000217)2.05110396
83Slow-growing hair (HP:0002217)2.02618276
84Abnormality of hair growth rate (HP:0011363)2.02618276
85Hypergammaglobulinemia (HP:0010702)2.02602721
86Alopecia of scalp (HP:0002293)2.02387725
87Macrocytic anemia (HP:0001972)2.01993003
88Pustule (HP:0200039)1.99380128
89Malnutrition (HP:0004395)1.98244383
90Sepsis (HP:0100806)1.96368014
91Septate vagina (HP:0001153)1.95240828
92Recurrent abscess formation (HP:0002722)1.93929261
93Abnormality of incisor morphology (HP:0011063)1.93777311
94Ridged nail (HP:0001807)1.92725948
95Ventricular fibrillation (HP:0001663)1.90381857
96Autoimmune hemolytic anemia (HP:0001890)1.88970495
97Conical tooth (HP:0000698)1.87936677
98Pterygium (HP:0001059)1.85361777
99Laryngomalacia (HP:0001601)1.83939384
100Achilles tendon contracture (HP:0001771)1.82499057
101Gastrointestinal infarctions (HP:0005244)1.81146400
102Premature loss of primary teeth (HP:0006323)1.79831907
103Skin ulcer (HP:0200042)1.77152273
104Premature ovarian failure (HP:0008209)1.74749812
105Dry hair (HP:0011359)1.73247790
106Absent hair (HP:0002298)1.72821776
107Type I diabetes mellitus (HP:0100651)1.72521710
108Hypoparathyroidism (HP:0000829)1.71677495
109Skin pits (HP:0100276)1.70867461
110Absent eyebrow (HP:0002223)1.70652203
111Paralysis (HP:0003470)1.68364226
112Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.67851027
113Abnormality of the Achilles tendon (HP:0005109)1.66728134
114Hypodontia (HP:0000668)1.65331402
115Pallor (HP:0000980)1.63767575
116Down-sloping shoulders (HP:0200021)1.63422387
117Blepharitis (HP:0000498)1.61833742
118Multifactorial inheritance (HP:0001426)1.61568633
119Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.58899113
120Mediastinal lymphadenopathy (HP:0100721)1.56460013
121Melanocytic nevus (HP:0000995)1.54974276
122Trismus (HP:0000211)1.54622404
123Hyperhidrosis (HP:0000975)1.54507856
124Hypoplasia of dental enamel (HP:0006297)1.54380304
125Sensory axonal neuropathy (HP:0003390)1.53521617
126Nasolacrimal duct obstruction (HP:0000579)1.52290872
127Verrucae (HP:0200043)1.51052013
128Papilloma (HP:0012740)1.51052013
129Chronic otitis media (HP:0000389)1.50466148
130Aplasia involving bones of the upper limbs (HP:0009823)1.47756166
131Aplasia of the phalanges of the hand (HP:0009802)1.47756166
132Aplasia involving bones of the extremities (HP:0009825)1.47756166
133Fragile skin (HP:0001030)1.47288919
134Ulnar claw (HP:0001178)1.46455608
135Gingivitis (HP:0000230)1.45488200
136Corneal dystrophy (HP:0001131)1.45124850
137Stomatitis (HP:0010280)1.43155714
138Carious teeth (HP:0000670)1.42016458
139Abnormality of the costochondral junction (HP:0000919)1.40345965
140Albinism (HP:0001022)1.39659245
141Anonychia (HP:0001798)1.39275768
142Choroideremia (HP:0001139)1.39005108

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R5.72024949
2MAPKAPK35.38817510
3MST44.43694822
4MAP3K33.96870139
5MAP3K22.99968922
6FER2.84864135
7RPS6KB22.63879112
8TRPM72.63414372
9IRAK42.36088024
10ERBB32.13252164
11MAPKAPK51.94308404
12MAP3K131.90765888
13LRRK21.82387827
14STK101.81131829
15IRAK11.78716009
16STK241.78504877
17MET1.78199399
18STK31.77772914
19BLK1.72196806
20JAK31.71768944
21PIK3CG1.70718017
22EPHB21.69479965
23PIM21.67841190
24IRAK31.63732680
25DYRK1B1.62855258
26TGFBR11.61994960
27CSK1.59904958
28LATS11.55702724
29CDK31.50259565
30MAPK71.49009577
31MAP3K141.46949100
32EEF2K1.43295848
33ERN11.43284381
34PRPF4B1.35622639
35RIPK11.33810021
36FGR1.29205257
37BCR1.26414387
38KIT1.23307909
39FGFR21.22522690
40MAP3K121.20886448
41IRAK21.15094019
42JAK11.12495794
43MAP3K111.08224770
44GRK71.07324686
45FGFR11.07245136
46TGFBR21.06626310
47TAOK21.05583090
48EPHA21.03179917
49TESK11.02502660
50MAP3K10.96901040
51NTRK20.96835581
52TAOK30.95020156
53DDR20.93842536
54EPHA30.92972521
55ZAP700.92898483
56NME20.92852238
57NLK0.89971848
58WNK10.88745402
59STK38L0.88526089
60MAPKAPK20.88423180
61MATK0.87971302
62ITK0.87635586
63SGK20.85901511
64SGK4940.85893001
65SGK2230.85893001
66FGFR40.84998674
67GRK60.84769620
68CDK60.84695228
69GRK50.80441644
70BMPR20.79900661
71EIF2AK20.78678634
72MAPK150.77592602
73MAP2K60.77419137
74CHUK0.77345143
75TXK0.76815882
76PTK60.75078130
77CDC42BPA0.73467401
78TAOK10.73264067
79MAP4K10.73180551
80FGFR30.72186036
81DYRK30.71217814
82KSR20.69759665
83ARAF0.68136383
84MAP3K70.67515184
85LATS20.65655375
86ABL20.64669725
87SGK30.64477218
88GRK10.63613966
89IKBKB0.62929485
90ADRBK10.62471002
91TYK20.62461140
92RPS6KA40.60670135
93PRKD10.60167209
94LIMK10.60129203
95EPHA40.59492491
96CDK190.58708403
97IKBKE0.57902623
98TTN0.56610393
99ADRBK20.55702955
100NEK60.55481425
101CDK90.55468002
102MAPK120.55260630
103CDK120.55220245
104PAK30.54512345
105BTK0.54484649
106MOS0.54253299
107CASK0.52253157
108LYN0.51805075
109ILK0.51140216
110MAP2K10.50547667
111OBSCN0.49301944
112TNIK0.47608799
113SYK0.44727807
114PRKCE0.44662348
115MAP2K20.44335178
116SRPK10.43881821
117PBK0.43589654
118MAP3K50.43521805
119STK110.41128277
120CSNK1D0.40501275
121PKN10.40460565
122MAP3K90.40238558
123LCK0.39178358
124ERBB20.36685549
125TBK10.36545240
126PRKCI0.35536253
127GSK3A0.34379398
128PTK20.32854349
129MAP2K40.32227963
130DYRK1A0.31894274
131HIPK20.31527824
132RIPK40.30535759
133ROCK10.30438857
134ABL10.29947893
135HCK0.29662561
136MARK20.28578276
137AURKA0.27468700
138TYRO30.26725244
139EPHB10.26476032
140RPS6KA10.26278195
141MAPK40.25917820
142BMPR1B0.25504229
143MAP2K30.24985224
144JAK20.24391138
145MAP3K60.23387522

Predicted pathways (KEGG)

RankGene SetZ-score
1Cyanoamino acid metabolism_Homo sapiens_hsa004605.70539314
2Ribosome_Homo sapiens_hsa030103.97006930
3Sphingolipid metabolism_Homo sapiens_hsa006003.76361955
4Linoleic acid metabolism_Homo sapiens_hsa005913.46334972
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.45830835
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.37414626
7Arachidonic acid metabolism_Homo sapiens_hsa005903.01475240
8Fatty acid elongation_Homo sapiens_hsa000622.28864069
9Histidine metabolism_Homo sapiens_hsa003402.13173026
10Ether lipid metabolism_Homo sapiens_hsa005652.08495292
11Leishmaniasis_Homo sapiens_hsa051402.02124334
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.00153784
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.76275212
14Retinol metabolism_Homo sapiens_hsa008301.71626394
15Phenylalanine metabolism_Homo sapiens_hsa003601.69481242
16NF-kappa B signaling pathway_Homo sapiens_hsa040641.58887541
17ABC transporters_Homo sapiens_hsa020101.49948572
18Allograft rejection_Homo sapiens_hsa053301.46357016
19Influenza A_Homo sapiens_hsa051641.40085878
20VEGF signaling pathway_Homo sapiens_hsa043701.30781517
21Staphylococcus aureus infection_Homo sapiens_hsa051501.30158751
22Malaria_Homo sapiens_hsa051441.28545058
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.28365437
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.27102219
25Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.25765778
26Adherens junction_Homo sapiens_hsa045201.24716993
27Tight junction_Homo sapiens_hsa045301.24576757
28Legionellosis_Homo sapiens_hsa051341.19292074
29Renin secretion_Homo sapiens_hsa049241.17334765
30Autoimmune thyroid disease_Homo sapiens_hsa053201.17265918
31Bladder cancer_Homo sapiens_hsa052191.15679932
32Sphingolipid signaling pathway_Homo sapiens_hsa040711.13004364
33Chemical carcinogenesis_Homo sapiens_hsa052041.12664054
34Acute myeloid leukemia_Homo sapiens_hsa052211.12481873
35Inositol phosphate metabolism_Homo sapiens_hsa005621.11359596
36Axon guidance_Homo sapiens_hsa043601.09858688
37Phagosome_Homo sapiens_hsa041451.07889691
38Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.07320327
39Chemokine signaling pathway_Homo sapiens_hsa040621.06929565
40Basal cell carcinoma_Homo sapiens_hsa052171.05030465
41African trypanosomiasis_Homo sapiens_hsa051431.03795238
42Measles_Homo sapiens_hsa051621.02248425
43B cell receptor signaling pathway_Homo sapiens_hsa046621.01623040
44Graft-versus-host disease_Homo sapiens_hsa053321.01191888
45Serotonergic synapse_Homo sapiens_hsa047261.00514007
46Asthma_Homo sapiens_hsa053100.99828125
47p53 signaling pathway_Homo sapiens_hsa041150.98514877
48Herpes simplex infection_Homo sapiens_hsa051680.96325915
49Tyrosine metabolism_Homo sapiens_hsa003500.94665003
50GnRH signaling pathway_Homo sapiens_hsa049120.94089527
51Salmonella infection_Homo sapiens_hsa051320.93372645
52Pancreatic secretion_Homo sapiens_hsa049720.92558432
53Intestinal immune network for IgA production_Homo sapiens_hsa046720.88949471
54Type I diabetes mellitus_Homo sapiens_hsa049400.87940732
55Caffeine metabolism_Homo sapiens_hsa002320.87632845
56Choline metabolism in cancer_Homo sapiens_hsa052310.87305334
57Phototransduction_Homo sapiens_hsa047440.86896133
58Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.83804606
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83539503
60Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.83039072
61ECM-receptor interaction_Homo sapiens_hsa045120.82281087
62Glutathione metabolism_Homo sapiens_hsa004800.81358168
63Fat digestion and absorption_Homo sapiens_hsa049750.81014358
64Prolactin signaling pathway_Homo sapiens_hsa049170.80618156
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.80375361
66Lysosome_Homo sapiens_hsa041420.80192724
67Hippo signaling pathway_Homo sapiens_hsa043900.79321590
68Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.78849934
69Pertussis_Homo sapiens_hsa051330.77773126
70Amoebiasis_Homo sapiens_hsa051460.77630003
71Proteoglycans in cancer_Homo sapiens_hsa052050.77499225
72Shigellosis_Homo sapiens_hsa051310.73836529
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.73781433
74Long-term depression_Homo sapiens_hsa047300.72918721
75Melanogenesis_Homo sapiens_hsa049160.72771138
76Antigen processing and presentation_Homo sapiens_hsa046120.72428423
77Ras signaling pathway_Homo sapiens_hsa040140.71413160
78Collecting duct acid secretion_Homo sapiens_hsa049660.71194545
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71066490
80Fatty acid biosynthesis_Homo sapiens_hsa000610.70063051
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69698387
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68170871
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.66583380
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65154028
85Hepatitis B_Homo sapiens_hsa051610.64636671
86Platelet activation_Homo sapiens_hsa046110.64501933
87MicroRNAs in cancer_Homo sapiens_hsa052060.63812152
88Hepatitis C_Homo sapiens_hsa051600.63425929
89Glycerophospholipid metabolism_Homo sapiens_hsa005640.62758050
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.62472904
91Viral myocarditis_Homo sapiens_hsa054160.61064791
92Jak-STAT signaling pathway_Homo sapiens_hsa046300.60817373
93ErbB signaling pathway_Homo sapiens_hsa040120.60496154
94Apoptosis_Homo sapiens_hsa042100.59384356
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.59202024
96Mineral absorption_Homo sapiens_hsa049780.56639389
97Renal cell carcinoma_Homo sapiens_hsa052110.56393900
98Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56103584
99Ovarian steroidogenesis_Homo sapiens_hsa049130.55488283
100FoxO signaling pathway_Homo sapiens_hsa040680.54946907
101Notch signaling pathway_Homo sapiens_hsa043300.54567268
102MAPK signaling pathway_Homo sapiens_hsa040100.54221607
103Gastric acid secretion_Homo sapiens_hsa049710.52254756
104Pancreatic cancer_Homo sapiens_hsa052120.50185790
105Toxoplasmosis_Homo sapiens_hsa051450.50074358
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49872735
107Dorso-ventral axis formation_Homo sapiens_hsa043200.48645131
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46931443
109AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43428602
110Gap junction_Homo sapiens_hsa045400.43231463
111Hedgehog signaling pathway_Homo sapiens_hsa043400.43195409
112Hematopoietic cell lineage_Homo sapiens_hsa046400.42435385
113Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.41334953
114T cell receptor signaling pathway_Homo sapiens_hsa046600.40658303
115Thyroid cancer_Homo sapiens_hsa052160.40588807
116Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40431072
117Phosphatidylinositol signaling system_Homo sapiens_hsa040700.39248815
118Salivary secretion_Homo sapiens_hsa049700.38003963
119Steroid biosynthesis_Homo sapiens_hsa001000.37654714
120Vibrio cholerae infection_Homo sapiens_hsa051100.37227055
121beta-Alanine metabolism_Homo sapiens_hsa004100.36172562
122Oxytocin signaling pathway_Homo sapiens_hsa049210.35256747
123TGF-beta signaling pathway_Homo sapiens_hsa043500.34998449
124Sulfur metabolism_Homo sapiens_hsa009200.34646681
125Tuberculosis_Homo sapiens_hsa051520.34201047
126Wnt signaling pathway_Homo sapiens_hsa043100.33567932
127Rap1 signaling pathway_Homo sapiens_hsa040150.33313935
128Endocytosis_Homo sapiens_hsa041440.32612298
129Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.32483696
130Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.31234233
131Protein digestion and absorption_Homo sapiens_hsa049740.30729148
132Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.30574031
133Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30572255
134Circadian rhythm_Homo sapiens_hsa047100.30244715
135Calcium signaling pathway_Homo sapiens_hsa040200.30010472
136TNF signaling pathway_Homo sapiens_hsa046680.29319320
137Olfactory transduction_Homo sapiens_hsa047400.28684189
138Osteoclast differentiation_Homo sapiens_hsa043800.28397709
139Rheumatoid arthritis_Homo sapiens_hsa053230.26713043
140Endometrial cancer_Homo sapiens_hsa052130.24932768
141Toll-like receptor signaling pathway_Homo sapiens_hsa046200.24763772
142Non-small cell lung cancer_Homo sapiens_hsa052230.24621939
143SNARE interactions in vesicular transport_Homo sapiens_hsa041300.24053760
144Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.23839402
145Estrogen signaling pathway_Homo sapiens_hsa049150.22715195

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