LMCD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the LIM-domain family of zinc finger proteins. The encoded protein contains an N-terminal cysteine-rich domain and two C-terminal LIM domains. The presence of LIM domains suggests involvement in protein-protein interactions. The protein may act as a co-regulator of transcription along with other transcription factors. Alternate splicing results in multiple transcript variants of this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-myosin filament sliding (GO:0033275)8.38913567
2muscle filament sliding (GO:0030049)8.38913567
3regulation of skeletal muscle contraction (GO:0014819)7.17729146
4actin-mediated cell contraction (GO:0070252)7.10406871
5plasma membrane repair (GO:0001778)6.70758427
6sarcomere organization (GO:0045214)5.78521624
7skeletal muscle contraction (GO:0003009)5.49730395
8actin filament-based movement (GO:0030048)5.35014280
9myofibril assembly (GO:0030239)5.20199421
10sarcoplasmic reticulum calcium ion transport (GO:0070296)5.19595631
11negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.14500302
12cardiac myofibril assembly (GO:0055003)4.82248954
13positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.63255673
14cartilage development involved in endochondral bone morphogenesis (GO:0060351)4.59862779
15striated muscle contraction (GO:0006941)4.26676700
16skeletal muscle fiber development (GO:0048741)4.22948843
17negative regulation of potassium ion transmembrane transport (GO:1901380)4.19288307
18actomyosin structure organization (GO:0031032)4.14946863
19regulation of relaxation of muscle (GO:1901077)4.09934641
20skeletal muscle adaptation (GO:0043501)4.08239597
21regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.01468208
22cytidine metabolic process (GO:0046087)3.96779766
23cytidine catabolic process (GO:0006216)3.96779766
24cytidine deamination (GO:0009972)3.96779766
25response to inactivity (GO:0014854)3.91880835
26cartilage condensation (GO:0001502)3.85158212
27cell aggregation (GO:0098743)3.85158212
28pyrimidine ribonucleoside catabolic process (GO:0046133)3.80897089
29muscle contraction (GO:0006936)3.79623137
30skeletal muscle tissue development (GO:0007519)3.78446327
31keratan sulfate catabolic process (GO:0042340)3.77035898
32regulation of cell communication by electrical coupling (GO:0010649)3.76310452
33regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.75074238
34replacement ossification (GO:0036075)3.65932865
35endochondral ossification (GO:0001958)3.65932865
36regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.63300572
37chondrocyte development (GO:0002063)3.63110227
38protein heterotrimerization (GO:0070208)3.61124370
39collagen fibril organization (GO:0030199)3.59177290
40cardiac muscle contraction (GO:0060048)3.57300250
41myotube cell development (GO:0014904)3.55733666
42cardiac muscle cell development (GO:0055013)3.54140243
43regulation of sequestering of triglyceride (GO:0010889)3.52430711
44cardiac cell development (GO:0055006)3.46072444
45endothelial cell morphogenesis (GO:0001886)3.44569968
46metanephric mesenchyme development (GO:0072075)3.42853574
47muscle system process (GO:0003012)3.41800661
48cellular polysaccharide catabolic process (GO:0044247)3.37472539
49protein hydroxylation (GO:0018126)3.34936896
50regulation of actin filament-based movement (GO:1903115)3.30833390
51muscle cell fate commitment (GO:0042693)3.30832582
52creatine metabolic process (GO:0006600)3.30076247
53NADH metabolic process (GO:0006734)3.26373265
54response to muscle activity (GO:0014850)3.25661775
55heart trabecula formation (GO:0060347)3.23584699
56cardiac muscle tissue morphogenesis (GO:0055008)3.22840481
57carnitine shuttle (GO:0006853)3.21262526
58tricarboxylic acid cycle (GO:0006099)3.21180253
59kidney mesenchyme development (GO:0072074)3.20899555
60muscle fiber development (GO:0048747)3.17400491
61regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.17130986
62notochord development (GO:0030903)3.16917014
63muscle tissue morphogenesis (GO:0060415)3.15266326
64response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.13039862
65regulation of p38MAPK cascade (GO:1900744)3.04581930
66glucan biosynthetic process (GO:0009250)3.03327783
67glycogen biosynthetic process (GO:0005978)3.03327783
68positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.02903523
69chondrocyte proliferation (GO:0035988)3.01058855
70negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.01033964
71response to gravity (GO:0009629)3.00996630
72myoblast fusion (GO:0007520)3.00994406
73polysaccharide catabolic process (GO:0000272)3.00958148
74peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.00141931
75purine nucleotide salvage (GO:0032261)2.99365894
76glomerular basement membrane development (GO:0032836)2.96019918
77regulation of the force of heart contraction (GO:0002026)2.95846511
78striated muscle cell development (GO:0055002)2.95615887
79negative regulation of protein localization to cell surface (GO:2000009)2.93956680
80peptidyl-proline hydroxylation (GO:0019511)2.93934148
81glycogen catabolic process (GO:0005980)2.93119526
82extracellular fibril organization (GO:0043206)2.91986208
83negative regulation of cardiac muscle tissue growth (GO:0055022)2.90705362
84negative regulation of heart growth (GO:0061117)2.90705362
85regulation of sarcomere organization (GO:0060297)2.90611983
86muscle hypertrophy (GO:0014896)2.88564639
87cell migration involved in heart development (GO:0060973)2.88476712
88striated muscle tissue development (GO:0014706)2.88296913
89chondroitin sulfate biosynthetic process (GO:0030206)2.86933006
90regulation of striated muscle contraction (GO:0006942)2.86743534
91glycogen metabolic process (GO:0005977)2.86529932
92muscle organ morphogenesis (GO:0048644)2.83459468
93muscle tissue development (GO:0060537)2.82914704
94* regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.81452646
95regulation of acyl-CoA biosynthetic process (GO:0050812)2.81090376
96positive regulation of cartilage development (GO:0061036)2.80693250
97skeletal muscle tissue regeneration (GO:0043403)2.78271177
98cellular glucan metabolic process (GO:0006073)2.78164571
99glucan metabolic process (GO:0044042)2.78164571
100regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.77882268
101positive regulation of extracellular matrix organization (GO:1903055)2.75744909
102response to activity (GO:0014823)2.73482112
103fatty acid transmembrane transport (GO:1902001)2.72740157
104extracellular matrix assembly (GO:0085029)2.72347188
105positive regulation of myoblast differentiation (GO:0045663)2.72311491
106ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.71223120
107glucan catabolic process (GO:0009251)2.70833364
108striated muscle adaptation (GO:0014888)2.69959909
109adult heart development (GO:0007512)2.69676582
110positive regulation of chondrocyte differentiation (GO:0032332)2.69189273
111muscle organ development (GO:0007517)2.68429027
112positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.67471728
113muscle structure development (GO:0061061)2.67389795
114regulation of myoblast differentiation (GO:0045661)2.65793414
115striated muscle hypertrophy (GO:0014897)2.65731934
116regulation of membrane repolarization (GO:0060306)2.65229493
117heart contraction (GO:0060047)2.64818327
118heart process (GO:0003015)2.64818327
119positive regulation of p38MAPK cascade (GO:1900745)2.63682438
120carnitine transmembrane transport (GO:1902603)2.63076040
121collagen metabolic process (GO:0032963)2.62804309
122positive regulation of myotube differentiation (GO:0010831)2.62719697
123vascular endothelial growth factor signaling pathway (GO:0038084)2.62458852
124collagen catabolic process (GO:0030574)2.62356463
125fibroblast migration (GO:0010761)2.61821836
126syncytium formation by plasma membrane fusion (GO:0000768)2.61484782
127cardiac muscle hypertrophy (GO:0003300)2.61215302
128regulation of tight junction assembly (GO:2000810)2.61206740
129endocrine hormone secretion (GO:0060986)2.60015491
130regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.59648147
131regulation of cofactor metabolic process (GO:0051193)2.57706822
132regulation of coenzyme metabolic process (GO:0051196)2.57706822
133regulation of skeletal muscle cell differentiation (GO:2001014)2.57357447
134lipid particle organization (GO:0034389)2.56781208
135muscle cell development (GO:0055001)2.56457390
136muscle cell cellular homeostasis (GO:0046716)2.55974705
137ovulation from ovarian follicle (GO:0001542)2.55098662
138retina vasculature morphogenesis in camera-type eye (GO:0061299)2.50629334
139regulation of integrin-mediated signaling pathway (GO:2001044)2.50004415
140muscle adaptation (GO:0043500)2.48713694
141striated muscle atrophy (GO:0014891)2.48182366
142cardiac muscle adaptation (GO:0014887)2.47938652
143muscle hypertrophy in response to stress (GO:0003299)2.47938652

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.52311609
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.42871957
3RARG_19884340_ChIP-ChIP_MEFs_Mouse4.23190031
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.18831745
5BP1_19119308_ChIP-ChIP_Hs578T_Human2.82018175
6CLOCK_20551151_ChIP-Seq_293T_Human2.76962351
7* ESR1_21235772_ChIP-Seq_MCF-7_Human2.56594648
8EP300_21415370_ChIP-Seq_HL-1_Mouse2.48535197
9* TBX20_22080862_ChIP-Seq_HEART_Mouse2.47574153
10* TBX20_22328084_ChIP-Seq_HEART_Mouse2.47574153
11* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.38078583
12TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.35843353
13PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.28310349
14* ESR2_21235772_ChIP-Seq_MCF-7_Human2.27940409
15CJUN_26792858_Chip-Seq_BT549_Human2.18250083
16HIF1A_21447827_ChIP-Seq_MCF-7_Human2.14107135
17ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.12691000
18CDX2_19796622_ChIP-Seq_MESCs_Mouse2.10806739
19GBX2_23144817_ChIP-Seq_PC3_Human2.03445388
20ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.01403663
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.01023458
22* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.97705074
23AR_21572438_ChIP-Seq_LNCaP_Human1.91830013
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.89762398
25EZH2_22144423_ChIP-Seq_EOC_Human1.89252864
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.84929174
27CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.76913319
28MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.73113980
29* ESR1_20079471_ChIP-ChIP_T-47D_Human1.72901198
30SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.72774931
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.67895843
32WT1_19549856_ChIP-ChIP_CCG9911_Human1.67510395
33GATA2_21666600_ChIP-Seq_HMVEC_Human1.56794466
34RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56767761
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.55844123
36EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.53375981
37* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.52650683
38* PIAS1_25552417_ChIP-Seq_VCAP_Human1.51098103
39* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.50878888
40* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.50878888
41* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.43726108
42SMC1_22415368_ChIP-Seq_MEFs_Mouse1.43654000
43NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.40579175
44EED_16625203_ChIP-ChIP_MESCs_Mouse1.40574990
45TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.39290583
46CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.38545420
47TP53_20018659_ChIP-ChIP_R1E_Mouse1.36893847
48PPAR_26484153_Chip-Seq_NCI-H1993_Human1.34366324
49EZH2_18974828_ChIP-Seq_MESCs_Mouse1.33964618
50RNF2_18974828_ChIP-Seq_MESCs_Mouse1.33964618
51ZNF263_19887448_ChIP-Seq_K562_Human1.33622140
52P63_26484246_Chip-Seq_KERATINOCYTES_Human1.33244856
53BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.32772256
54EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.32149649
55NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.30633468
56* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.29508649
57PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28541527
58SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.28409022
59EZH2_27304074_Chip-Seq_ESCs_Mouse1.27880801
60SMC3_22415368_ChIP-Seq_MEFs_Mouse1.27533914
61ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.27038684
62* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.25824889
63LXR_22158963_ChIP-Seq_LIVER_Mouse1.25500941
64GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.25023105
65* SOX2_20726797_ChIP-Seq_SW620_Human1.24398919
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.24274514
67ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.23529765
68UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.23322791
69PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.23007198
70SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.22789368
71SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.22789368
72ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.22457712
73AHR_22903824_ChIP-Seq_MCF-7_Human1.21775240
74WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.21329217
75ZFP57_27257070_Chip-Seq_ESCs_Mouse1.17887078
76STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.16200058
77SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.15368946
78PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.13492159
79SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.12610806
80ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12239514
81MTF2_20144788_ChIP-Seq_MESCs_Mouse1.11819705
82* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10330107
83RXR_22158963_ChIP-Seq_LIVER_Mouse1.09336214
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.09261979
85* RACK7_27058665_Chip-Seq_MCF-7_Human1.08218695
86SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.08149023
87TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.06301803
88ATF3_27146783_Chip-Seq_COLON_Human1.06166486
89* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05555023
90KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.05475081
91CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.05192919
92SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04137203
93* NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.03651332
94CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03418342
95* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.03373942
96TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.02814841
97JARID2_20075857_ChIP-Seq_MESCs_Mouse1.02250122
98* SMAD4_21799915_ChIP-Seq_A2780_Human1.02116932
99GATA4_21415370_ChIP-Seq_HL-1_Mouse1.01667918
100AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01231369
101RXR_22108803_ChIP-Seq_LS180_Human0.99123338
102* BRD4_25478319_ChIP-Seq_HGPS_Human0.99043043
103FOXM1_26456572_ChIP-Seq_MCF-7_Human0.98991175
104ISL1_27105846_Chip-Seq_CPCs_Mouse0.98963026
105TP53_18474530_ChIP-ChIP_U2OS_Human0.98578150
106NFIB_24661679_ChIP-Seq_LUNG_Mouse0.97740716
107SA1_22415368_ChIP-Seq_MEFs_Mouse0.97581898
108SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.97456065
109SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96827719
110HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95995101
111SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95980788
112* SMAD3_21741376_ChIP-Seq_HESCs_Human0.95090169
113PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94862317
114UBF1/2_26484160_Chip-Seq_HMECs_Human0.94758212
115* FOXO3_23340844_ChIP-Seq_DLD1_Human0.94179382
116SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91894918
117SUZ12_27294783_Chip-Seq_NPCs_Mouse0.90305656
118CBX2_27304074_Chip-Seq_ESCs_Mouse0.89897351
119GATA1_22025678_ChIP-Seq_K562_Human0.89812197
120SALL4_18804426_ChIP-ChIP_XEN_Mouse0.89397159
121EZH2_27294783_Chip-Seq_NPCs_Mouse0.89356090
122CSB_26484114_Chip-Seq_FIBROBLAST_Human0.88410007
123PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.87833255
124RNF2_27304074_Chip-Seq_ESCs_Mouse0.87807879
125TP53_16413492_ChIP-PET_HCT116_Human0.87227825
126EZH2_27294783_Chip-Seq_ESCs_Mouse0.86127090
127NR3C1_23031785_ChIP-Seq_PC12_Mouse0.86125429
128KDM2B_26808549_Chip-Seq_SUP-B15_Human0.86010085
129* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85738241
130FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.85576603
131* GATA3_24758297_ChIP-Seq_MCF-7_Human0.84751597
132P300_27058665_Chip-Seq_ZR-75-30cells_Human0.83966658
133SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.82634912
134CTCF_21964334_Chip-Seq_Bcells_Human0.80324481
135TP53_23651856_ChIP-Seq_MEFs_Mouse0.80127658
136PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.79945387
137KDM2B_26808549_Chip-Seq_K562_Human0.78570250
138EGR1_19032775_ChIP-ChIP_M12_Human0.78259690

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue5.35252738
2MP0000751_myopathy4.94276941
3MP0000749_muscle_degeneration4.22135301
4MP0004145_abnormal_muscle_electrophysio3.65856028
5MP0002837_dystrophic_cardiac_calcinosis3.65725955
6MP0004084_abnormal_cardiac_muscle3.30502002
7MP0004036_abnormal_muscle_relaxation3.29754180
8MP0008438_abnormal_cutaneous_collagen3.06689809
9MP0005503_abnormal_tendon_morphology3.01113815
10MP0000750_abnormal_muscle_regeneration2.60247146
11MP0004087_abnormal_muscle_fiber2.59633949
12MP0002106_abnormal_muscle_physiology2.58806128
13MP0003279_aneurysm2.48989065
14MP0005620_abnormal_muscle_contractility2.45801276
15MP0000747_muscle_weakness2.44668633
16MP0000759_abnormal_skeletal_muscle2.40838680
17MP0005369_muscle_phenotype2.30651660
18MP0005330_cardiomyopathy2.29736606
19MP0003705_abnormal_hypodermis_morpholog2.23341542
20MP0004215_abnormal_myocardial_fiber2.22803361
21MP0009384_cardiac_valve_regurgitation2.22781312
22MP0005275_abnormal_skin_tensile2.18222646
23MP0009250_abnormal_appendicular_skeleto2.17087035
24MP0004134_abnormal_chest_morphology2.09440728
25MP0002108_abnormal_muscle_morphology2.02130941
26MP0002269_muscular_atrophy2.02016303
27MP0004484_altered_response_of1.97237182
28MP0002972_abnormal_cardiac_muscle1.94127943
29MP0001958_emphysema1.93379454
30MP0004130_abnormal_muscle_cell1.86924959
31MP0008775_abnormal_heart_ventricle1.77711091
32MP0002933_joint_inflammation1.76717145
33MP0004233_abnormal_muscle_weight1.68778970
34MP0001661_extended_life_span1.66495266
35MP0004272_abnormal_basement_membrane1.63476157
36MP0000733_abnormal_muscle_development1.58757758
37MP0001544_abnormal_cardiovascular_syste1.55729619
38MP0005385_cardiovascular_system_phenoty1.55729619
39MP0000163_abnormal_cartilage_morphology1.55474131
40MP0010368_abnormal_lymphatic_system1.52268505
41MP0010630_abnormal_cardiac_muscle1.48882857
42MP0001879_abnormal_lymphatic_vessel1.46549259
43MP0000343_altered_response_to1.44171122
44MP0006138_congestive_heart_failure1.41141933
45MP0005451_abnormal_body_composition1.41048162
46MP0000013_abnormal_adipose_tissue1.39351281
47MP0003566_abnormal_cell_adhesion1.38749892
48MP0003828_pulmonary_edema1.36542136
49MP0002332_abnormal_exercise_endurance1.36266421
50MP0003950_abnormal_plasma_membrane1.34746805
51MP0002896_abnormal_bone_mineralization1.32639346
52MP0000762_abnormal_tongue_morphology1.28728155
53MP0002115_abnormal_skeleton_extremities1.27870957
54MP0000767_abnormal_smooth_muscle1.25055258
55MP0005508_abnormal_skeleton_morphology1.24811262
56MP0009780_abnormal_chondrocyte_physiolo1.24351635
57MP0003137_abnormal_impulse_conducting1.23578901
58MP0001299_abnormal_eye_distance/1.22042294
59MP0002282_abnormal_trachea_morphology1.11519040
60MP0005623_abnormal_meninges_morphology1.10742821
61MP0006054_spinal_hemorrhage1.08954085
62MP0005666_abnormal_adipose_tissue1.07997175
63MP0003385_abnormal_body_wall0.98968412
64MP0002113_abnormal_skeleton_development0.98320483
65MP0002295_abnormal_pulmonary_circulatio0.97868643
66MP0002876_abnormal_thyroid_physiology0.97198644
67MP0001542_abnormal_bone_strength0.97062411
68MP0004085_abnormal_heartbeat0.96728741
69MP0005257_abnormal_intraocular_pressure0.94461375
70MP0002127_abnormal_cardiovascular_syste0.94310385
71MP0003941_abnormal_skin_development0.93842714
72MP0002254_reproductive_system_inflammat0.92801448
73MP0005390_skeleton_phenotype0.88542568
74MP0002128_abnormal_blood_circulation0.88266385
75MP0002089_abnormal_postnatal_growth/wei0.87641493
76MP0005375_adipose_tissue_phenotype0.86332651
77MP0003221_abnormal_cardiomyocyte_apopto0.85496058
78MP0005023_abnormal_wound_healing0.82949372
79MP0001270_distended_abdomen0.82702942
80MP0005266_abnormal_metabolism0.82601238
81MP0002109_abnormal_limb_morphology0.81831076
82MP0004185_abnormal_adipocyte_glucose0.81698131
83MP0010030_abnormal_orbit_morphology0.81299093
84MP0002909_abnormal_adrenal_gland0.80029638
85MP0000266_abnormal_heart_morphology0.79944697
86MP0001533_abnormal_skeleton_physiology0.78999552
87MP0005165_increased_susceptibility_to0.78421587
88MP0000230_abnormal_systemic_arterial0.75074693
89MP0003091_abnormal_cell_migration0.73589895
90MP0006036_abnormal_mitochondrial_physio0.69759287
91MP0002971_abnormal_brown_adipose0.68614723
92MP0000003_abnormal_adipose_tissue0.67267463
93MP0000049_abnormal_middle_ear0.67225051
94MP0001243_abnormal_dermal_layer0.67055862
95MP0004510_myositis0.66997184
96MP0003795_abnormal_bone_structure0.66989357
97MP0003011_delayed_dark_adaptation0.65550175
98MP0005595_abnormal_vascular_smooth0.65126930
99MP0003755_abnormal_palate_morphology0.64808818
100MP0003942_abnormal_urinary_system0.64306306
101MP0003045_fibrosis0.63623573
102MP0003959_abnormal_lean_body0.62920503
103MP0005670_abnormal_white_adipose0.62778353
104MP0005171_absent_coat_pigmentation0.61394878
105MP0001614_abnormal_blood_vessel0.60993476
106MP0003806_abnormal_nucleotide_metabolis0.60587037
107MP0002060_abnormal_skin_morphology0.60012202
108MP0000372_irregular_coat_pigmentation0.58633015
109MP0005164_abnormal_response_to0.58068432
110MP0004858_abnormal_nervous_system0.57651480
111MP0004270_analgesia0.56818334
112MP0002234_abnormal_pharynx_morphology0.56194216
113MP0002998_abnormal_bone_remodeling0.56099710
114MP0000249_abnormal_blood_vessel0.56028753
115MP0002114_abnormal_axial_skeleton0.48968718
116MP0000534_abnormal_ureter_morphology0.47230565
117MP0002078_abnormal_glucose_homeostasis0.45865437
118MP0003186_abnormal_redox_activity0.44780788

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)6.80727457
2Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)6.41261964
3Type 1 muscle fiber predominance (HP:0003803)6.20102327
4Nemaline bodies (HP:0003798)6.05173493
5Exercise-induced myalgia (HP:0003738)5.23219194
6Muscle fiber splitting (HP:0003555)4.92930941
7Exercise-induced muscle cramps (HP:0003710)4.90634157
8Epiphyseal dysplasia (HP:0002656)4.63123899
9Ulnar deviation of the wrist (HP:0003049)4.57112309
10Hypoplastic ischia (HP:0003175)4.42466208
11Metaphyseal cupping (HP:0003021)4.39336218
12Muscle hypertrophy of the lower extremities (HP:0008968)4.25609883
13Distal arthrogryposis (HP:0005684)4.24624649
14Calf muscle hypertrophy (HP:0008981)4.18807362
15Aplasia/Hypoplasia of the pubic bone (HP:0009104)4.13046093
16Irregular epiphyses (HP:0010582)4.01544582
17Hyporeflexia of lower limbs (HP:0002600)3.93386030
18Abnormality of the calf musculature (HP:0001430)3.88072515
19Abnormality of the ischium (HP:0003174)3.87831370
20Cupped ribs (HP:0000887)3.83828059
21Myopathic facies (HP:0002058)3.83227001
22Increased connective tissue (HP:0009025)3.71423000
23Metaphyseal dysplasia (HP:0100255)3.70061640
24EMG: myopathic abnormalities (HP:0003458)3.68360385
25Round ear (HP:0100830)3.55954236
26Abnormal tarsal ossification (HP:0008369)3.44965728
27Waddling gait (HP:0002515)3.34580321
28Centrally nucleated skeletal muscle fibers (HP:0003687)3.31031361
29Small epiphyses (HP:0010585)3.28116744
30Difficulty running (HP:0009046)3.24404393
31Abnormality of skeletal muscle fiber size (HP:0012084)3.22419190
32Hip contracture (HP:0003273)3.19257509
33Myoglobinuria (HP:0002913)3.17172887
34Calcaneovalgus deformity (HP:0001848)3.08642850
35Flat acetabular roof (HP:0003180)3.01983758
36Increased variability in muscle fiber diameter (HP:0003557)3.01282729
37Vitreoretinal degeneration (HP:0000655)2.97403672
38Sudden death (HP:0001699)2.92086656
39Limited hip movement (HP:0008800)2.92034552
40Neck muscle weakness (HP:0000467)2.91295879
41Muscle stiffness (HP:0003552)2.88342610
42Absent phalangeal crease (HP:0006109)2.87604725
43Myotonia (HP:0002486)2.86818545
44Mild short stature (HP:0003502)2.83803988
45Deformed tarsal bones (HP:0008119)2.80473319
46Distal lower limb muscle weakness (HP:0009053)2.80241801
47Spinal rigidity (HP:0003306)2.79356548
48Abnormality of the vertebral endplates (HP:0005106)2.74963949
49Genu varum (HP:0002970)2.72795174
50Aortic dissection (HP:0002647)2.70964390
51Mildly elevated creatine phosphokinase (HP:0008180)2.70319671
52Irregular vertebral endplates (HP:0003301)2.70264274
53Delayed epiphyseal ossification (HP:0002663)2.68602667
54Asymmetric septal hypertrophy (HP:0001670)2.60182658
55Right ventricular cardiomyopathy (HP:0011663)2.59042094
56Abnormality of the left ventricular outflow tract (HP:0011103)2.58927301
57Subaortic stenosis (HP:0001682)2.58927301
58Coxa vara (HP:0002812)2.58872074
59Difficulty climbing stairs (HP:0003551)2.58681290
60Abnormal foot bone ossification (HP:0010675)2.53907038
61Abnormality of the calcaneus (HP:0008364)2.53880398
62Ventricular tachycardia (HP:0004756)2.53533778
63Flat capital femoral epiphysis (HP:0003370)2.53395615
64Abnormality of femoral epiphyses (HP:0006499)2.52426306
65Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.52426306
66Rhabdomyolysis (HP:0003201)2.47236747
67Bundle branch block (HP:0011710)2.43132220
68Limb-girdle muscle atrophy (HP:0003797)2.39658401
69Aortic aneurysm (HP:0004942)2.39084821
70Ovoid vertebral bodies (HP:0003300)2.37797164
71Mesomelia (HP:0003027)2.36779788
72Soft skin (HP:0000977)2.35677415
73Abnormal finger flexion creases (HP:0006143)2.34652981
74Abnormality of the epiphysis of the femoral head (HP:0010574)2.33980050
75Bulbar palsy (HP:0001283)2.33794896
76Generalized muscle weakness (HP:0003324)2.33207515
77Abnormality of the pubic bones (HP:0003172)2.30915146
78Lipoatrophy (HP:0100578)2.28454044
79Protrusio acetabuli (HP:0003179)2.28309856
80Enlarged epiphyses (HP:0010580)2.26375356
81Scapular winging (HP:0003691)2.25245195
82Neonatal short-limb short stature (HP:0008921)2.22215896
83Vascular tortuosity (HP:0004948)2.20799714
84Slender build (HP:0001533)2.18624329
85Popliteal pterygium (HP:0009756)2.14873266
86Abnormality of the femoral head (HP:0003368)2.13718348
87Osteoarthritis (HP:0002758)2.11962899
88Premature rupture of membranes (HP:0001788)2.11721143
89Platyspondyly (HP:0000926)2.09889673
90Facial diplegia (HP:0001349)2.09562120
91Oligomenorrhea (HP:0000876)2.06905462
92Lumbar hyperlordosis (HP:0002938)2.05299654
93Abnormality of the shoulder girdle musculature (HP:0001435)2.05264558
94EMG: neuropathic changes (HP:0003445)2.05168069
95Rimmed vacuoles (HP:0003805)2.04180798
96Infantile muscular hypotonia (HP:0008947)2.03160888
97Limb-girdle muscle weakness (HP:0003325)2.01022357
98Beaking of vertebral bodies (HP:0004568)2.00969094
99Areflexia of lower limbs (HP:0002522)2.00939299
100Fatigable weakness (HP:0003473)2.00501858
101Abnormality of the neuromuscular junction (HP:0003398)2.00501858
102Cervical subluxation (HP:0003308)1.97463504
103Abnormality of carpal bone ossification (HP:0006257)1.96719616
104Weak cry (HP:0001612)1.95915303
105Breech presentation (HP:0001623)1.95022779
106Muscular dystrophy (HP:0003560)1.94322551
107Respiratory insufficiency due to muscle weakness (HP:0002747)1.94208687
108Broad metatarsal (HP:0001783)1.93565177
109Frequent falls (HP:0002359)1.93398339
110Short femoral neck (HP:0100864)1.92903375
111Hyperkalemia (HP:0002153)1.91468102
112Proximal amyotrophy (HP:0007126)1.88626868
113Dilated cardiomyopathy (HP:0001644)1.87046580
114Fetal akinesia sequence (HP:0001989)1.86838356
115Delayed gross motor development (HP:0002194)1.86595205
116Atrial fibrillation (HP:0005110)1.85978945
117Gowers sign (HP:0003391)1.83626152
118Flattened epiphyses (HP:0003071)1.81855736
119Wrist flexion contracture (HP:0001239)1.81721340
120Cerebral aneurysm (HP:0004944)1.81176516
121Bladder diverticulum (HP:0000015)1.79031833
122Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.75150394
123Arterial tortuosity (HP:0005116)1.71312355
124Malignant hyperthermia (HP:0002047)1.71190072
125Distal lower limb amyotrophy (HP:0008944)1.71085592
126Lower limb amyotrophy (HP:0007210)1.70444481
127Generalized amyotrophy (HP:0003700)1.69062787
128Fragile skin (HP:0001030)1.66241264
129Ankle contracture (HP:0006466)1.63090538
130Abnormal atrioventricular conduction (HP:0005150)1.61789568
131Hypoalphalipoproteinemia (HP:0003233)1.61698848
132Long clavicles (HP:0000890)1.61000926
133Metatarsus adductus (HP:0001840)1.59869260
134Abnormality of the foot musculature (HP:0001436)1.59764585
135Shallow orbits (HP:0000586)1.58107729
136Follicular hyperkeratosis (HP:0007502)1.53722915
137Heart block (HP:0012722)1.53334055
138Foot dorsiflexor weakness (HP:0009027)1.52817922

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN7.30864130
2TTN5.45132421
3PHKG23.37823045
4PHKG13.37823045
5PIK3CG2.94589115
6NME12.68146958
7MUSK2.65128943
8STK242.56189250
9MAP3K32.53569596
10TRIB32.50642341
11TIE12.33478524
12STK38L2.33105399
13DMPK2.24653196
14DDR22.23721161
15PDK22.04915950
16PIK3CA1.92689435
17MYLK1.89319854
18MAP2K31.84271352
19MAPK121.65372289
20PDK31.53550546
21PDK41.53550546
22ERN11.45996453
23LATS11.32731348
24PKN21.31120521
25MAP3K71.26841406
26PDGFRA1.25359347
27ERBB31.23976970
28TAOK11.21549581
29EPHA31.20351980
30PINK11.19196622
31TGFBR21.18456897
32BCKDK1.16709783
33EPHB21.15507568
34RIPK11.14774069
35FER1.12104539
36LMTK21.10618196
37PRKG21.08284979
38TAOK21.04514506
39LIMK11.01629667
40NEK10.97026026
41ROCK10.96992147
42LATS20.94546477
43TRPM70.92067728
44ZAK0.91286107
45ILK0.88094576
46MAP3K60.86533799
47EPHB10.86447185
48NLK0.86138808
49PIM20.80560977
50MAPKAPK30.79759519
51PTK2B0.78151724
52PAK30.73514114
53MAP3K120.73485373
54MAPK70.72760500
55GRK10.70884988
56KDR0.70570462
57TGFBR10.70131490
58EEF2K0.69784993
59CAMK10.62105991
60MAP3K110.60881299
61SIK10.59025635
62ABL20.58190318
63PTK60.58068898
64PRKD10.56527070
65STK30.55120332
66AKT30.53207308
67ADRBK10.52339701
68PRKAA20.49960719
69STK380.49403338
70MAP2K10.47801309
71NEK90.47109989
72MARK10.45548120
73AKT20.45401808
74PAK20.45378551
75MAP3K50.44567886
76WNK40.43781790
77CAMK2B0.43632396
78MAPK150.39908796
79PRKD20.39669630
80FGFR30.39144629
81CAMK2A0.38094669
82NUAK10.37844776
83PRKAA10.37407175
84SGK30.36712643
85CAMK40.36010010
86PNCK0.34518030
87ROCK20.34453021
88CAMK2G0.32823059
89SGK20.32599728
90CDC42BPA0.32108031
91PKN10.30936438
92FGFR10.30825016
93PRKG10.30797919
94PRKCE0.30255803
95CAMK2D0.30198890
96MAPK40.30040716
97RPS6KA20.29979763
98PDGFRB0.27962554
99LRRK20.27316207
100MET0.26752918
101INSRR0.26717375
102FRK0.25305535
103PTK20.25105675
104TESK10.23993769
105PAK40.23426839
106GSK3A0.22731872
107NME20.22178690
108ERBB40.21302193
109RPS6KA30.21252703
110BMX0.20194157
111FLT30.19851339
112PRKACG0.18142100
113MAP2K40.17831344
114MELK0.17654621
115PRKD30.17421538
116PRKACB0.16851014
117RPS6KA40.16785365
118EIF2AK30.16580499
119MAP2K60.16139957
120PDPK10.16071196
121DAPK30.15589593
122PLK20.14850892
123PRKACA0.14729747
124EPHA20.14247737
125MAPK110.13987941
126MTOR0.12972259
127NEK60.12799600
128MOS0.12718295
129MAP3K10.11717630

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.14289736
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.87436921
3Dilated cardiomyopathy_Homo sapiens_hsa054143.84703063
4ECM-receptor interaction_Homo sapiens_hsa045123.42841549
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.41780795
6Cardiac muscle contraction_Homo sapiens_hsa042603.06184338
7Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.95666392
8Focal adhesion_Homo sapiens_hsa045102.48581015
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.27024292
10Protein digestion and absorption_Homo sapiens_hsa049742.17272284
11Starch and sucrose metabolism_Homo sapiens_hsa005001.99347147
12Propanoate metabolism_Homo sapiens_hsa006401.85165649
13Parkinsons disease_Homo sapiens_hsa050121.66249409
14Fatty acid degradation_Homo sapiens_hsa000711.58612371
15Oxidative phosphorylation_Homo sapiens_hsa001901.56520937
16Malaria_Homo sapiens_hsa051441.42179569
17Arginine biosynthesis_Homo sapiens_hsa002201.39826692
18Insulin resistance_Homo sapiens_hsa049311.38974955
19Carbon metabolism_Homo sapiens_hsa012001.38158106
20Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.37239270
21Galactose metabolism_Homo sapiens_hsa000521.35972331
22Viral myocarditis_Homo sapiens_hsa054161.32974952
23Proteoglycans in cancer_Homo sapiens_hsa052051.31782713
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.28707867
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.28160744
26Alzheimers disease_Homo sapiens_hsa050101.27671897
27cGMP-PKG signaling pathway_Homo sapiens_hsa040221.27232224
28Oxytocin signaling pathway_Homo sapiens_hsa049211.23059705
29Tight junction_Homo sapiens_hsa045301.20685771
30Circadian rhythm_Homo sapiens_hsa047101.19428291
31Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.17604956
32Glucagon signaling pathway_Homo sapiens_hsa049221.15740949
33Fatty acid metabolism_Homo sapiens_hsa012121.14701786
34Pentose phosphate pathway_Homo sapiens_hsa000301.13411142
35Vascular smooth muscle contraction_Homo sapiens_hsa042701.12956040
36Insulin signaling pathway_Homo sapiens_hsa049101.11041563
37PI3K-Akt signaling pathway_Homo sapiens_hsa041511.07914328
38Arginine and proline metabolism_Homo sapiens_hsa003301.07548559
39Adherens junction_Homo sapiens_hsa045201.07392318
40Adipocytokine signaling pathway_Homo sapiens_hsa049201.06480043
41HIF-1 signaling pathway_Homo sapiens_hsa040661.05854538
42Nitrogen metabolism_Homo sapiens_hsa009101.04414315
43Phenylalanine metabolism_Homo sapiens_hsa003601.03596799
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.02516071
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.95719193
46Pyruvate metabolism_Homo sapiens_hsa006200.94025183
47Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.91487884
48TGF-beta signaling pathway_Homo sapiens_hsa043500.91487087
49beta-Alanine metabolism_Homo sapiens_hsa004100.90961188
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.88758922
51Tryptophan metabolism_Homo sapiens_hsa003800.87504589
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.83881518
53Amoebiasis_Homo sapiens_hsa051460.83166639
54Hippo signaling pathway_Homo sapiens_hsa043900.82500882
55Tyrosine metabolism_Homo sapiens_hsa003500.81746614
56Calcium signaling pathway_Homo sapiens_hsa040200.81073355
57Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78739032
58Huntingtons disease_Homo sapiens_hsa050160.78730645
59Sulfur metabolism_Homo sapiens_hsa009200.77986802
60AMPK signaling pathway_Homo sapiens_hsa041520.76491195
61Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.75675926
62Leukocyte transendothelial migration_Homo sapiens_hsa046700.75408022
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.75204222
64Basal cell carcinoma_Homo sapiens_hsa052170.72146572
65Butanoate metabolism_Homo sapiens_hsa006500.70660814
66Fatty acid elongation_Homo sapiens_hsa000620.69276588
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.68012091
68PPAR signaling pathway_Homo sapiens_hsa033200.66359147
69Histidine metabolism_Homo sapiens_hsa003400.66004227
70Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65930745
71Insulin secretion_Homo sapiens_hsa049110.63293037
72Platelet activation_Homo sapiens_hsa046110.62470947
73Glutathione metabolism_Homo sapiens_hsa004800.61645630
74Sphingolipid metabolism_Homo sapiens_hsa006000.61468544
75Fructose and mannose metabolism_Homo sapiens_hsa000510.56762837
76Mineral absorption_Homo sapiens_hsa049780.56438486
77Bladder cancer_Homo sapiens_hsa052190.55480122
78Sulfur relay system_Homo sapiens_hsa041220.55212883
79Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51608314
80Peroxisome_Homo sapiens_hsa041460.51249784
81Gap junction_Homo sapiens_hsa045400.49732482
82Ovarian steroidogenesis_Homo sapiens_hsa049130.48375464
83GnRH signaling pathway_Homo sapiens_hsa049120.47834765
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46653894
85Glycosaminoglycan degradation_Homo sapiens_hsa005310.46252333
86FoxO signaling pathway_Homo sapiens_hsa040680.46126858
87Biosynthesis of amino acids_Homo sapiens_hsa012300.46072995
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46072297
89Gastric acid secretion_Homo sapiens_hsa049710.45529853
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44903633
91Salivary secretion_Homo sapiens_hsa049700.44866263
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44792256
93VEGF signaling pathway_Homo sapiens_hsa043700.44739718
94Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.44642806
95Melanogenesis_Homo sapiens_hsa049160.44492533
96Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.44407511
97MAPK signaling pathway_Homo sapiens_hsa040100.44325672
98Rap1 signaling pathway_Homo sapiens_hsa040150.43866981
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43269641
100Folate biosynthesis_Homo sapiens_hsa007900.42326896
101Small cell lung cancer_Homo sapiens_hsa052220.42274505
102ABC transporters_Homo sapiens_hsa020100.41046917
103Fatty acid biosynthesis_Homo sapiens_hsa000610.40932756
104Complement and coagulation cascades_Homo sapiens_hsa046100.40428147
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40148345
106Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39188616
107Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38728489
108Lysine degradation_Homo sapiens_hsa003100.38137592
109Glycerolipid metabolism_Homo sapiens_hsa005610.38052503
110Olfactory transduction_Homo sapiens_hsa047400.37599801
111Renin secretion_Homo sapiens_hsa049240.37313379
112Renal cell carcinoma_Homo sapiens_hsa052110.37080617
113Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36038322
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35240775
115Pancreatic secretion_Homo sapiens_hsa049720.34412065
116Melanoma_Homo sapiens_hsa052180.33655522
117Hedgehog signaling pathway_Homo sapiens_hsa043400.33223619
118Caffeine metabolism_Homo sapiens_hsa002320.30980437
119Wnt signaling pathway_Homo sapiens_hsa043100.30660099
120Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30536059
121Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.29650645
122Arachidonic acid metabolism_Homo sapiens_hsa005900.28973275
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.28642673
124Toxoplasmosis_Homo sapiens_hsa051450.28026475
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27778089
126Aldosterone synthesis and secretion_Homo sapiens_hsa049250.26662406
127Pathways in cancer_Homo sapiens_hsa052000.26546479
128cAMP signaling pathway_Homo sapiens_hsa040240.26021347
129HTLV-I infection_Homo sapiens_hsa051660.25204366
130TNF signaling pathway_Homo sapiens_hsa046680.23762040

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