LMF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mannose metabolic process (GO:0006013)4.05253036
2negative regulation of cell killing (GO:0031342)3.44050402
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.44050402
4regulation of extracellular matrix disassembly (GO:0010715)3.42390411
5skin morphogenesis (GO:0043589)3.29359297
6protein localization to endosome (GO:0036010)3.27032302
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.24660789
8basement membrane organization (GO:0071711)3.21370817
9antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.13454894
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.13454894
11positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.12069689
12NIK/NF-kappaB signaling (GO:0038061)2.99771096
13DNA unwinding involved in DNA replication (GO:0006268)2.97735216
14stress fiber assembly (GO:0043149)2.94733947
15positive regulation of Cdc42 GTPase activity (GO:0043089)2.94667425
16regulation of early endosome to late endosome transport (GO:2000641)2.91603685
17adhesion of symbiont to host cell (GO:0044650)2.90714333
18virion attachment to host cell (GO:0019062)2.90714333
19modulation by symbiont of host defense response (GO:0052031)2.85989725
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.85989725
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.85989725
22positive regulation by organism of defense response of other organism involved in symbiotic interact2.85989725
23modulation by symbiont of host immune response (GO:0052553)2.85989725
24positive regulation by symbiont of host defense response (GO:0052509)2.85989725
25folic acid-containing compound biosynthetic process (GO:0009396)2.85798708
26regulation of protein heterodimerization activity (GO:0043497)2.83169278
27viral transcription (GO:0019083)2.81773181
28detection of bacterium (GO:0016045)2.76359199
29antigen processing and presentation of endogenous antigen (GO:0019883)2.76190151
30protein heterotrimerization (GO:0070208)2.74265624
31protein localization to kinetochore (GO:0034501)2.73365325
32positive regulation of receptor recycling (GO:0001921)2.73128484
33apoptotic cell clearance (GO:0043277)2.70711978
34negative regulation of cell size (GO:0045792)2.70141035
35response to peptidoglycan (GO:0032494)2.69708195
36translational termination (GO:0006415)2.69490660
37response to muramyl dipeptide (GO:0032495)2.69468605
38pentose-phosphate shunt (GO:0006098)2.68992630
39macrophage activation involved in immune response (GO:0002281)2.68441460
40endodermal cell differentiation (GO:0035987)2.68353956
41detection of other organism (GO:0098543)2.66931393
42semaphorin-plexin signaling pathway (GO:0071526)2.66458258
43vascular endothelial growth factor signaling pathway (GO:0038084)2.66158803
44response to laminar fluid shear stress (GO:0034616)2.64428196
45modulation by symbiont of host cellular process (GO:0044068)2.62918463
46morphogenesis of an endothelium (GO:0003159)2.59704266
47endothelial tube morphogenesis (GO:0061154)2.59704266
48cell-substrate junction assembly (GO:0007044)2.57699106
49positive regulation of extracellular matrix organization (GO:1903055)2.57338923
50adherens junction assembly (GO:0034333)2.55050602
51negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.53939532
52DNA strand elongation involved in DNA replication (GO:0006271)2.53920824
53apoptotic process involved in morphogenesis (GO:0060561)2.53780886
54positive regulation of histone deacetylation (GO:0031065)2.52562760
55thymic T cell selection (GO:0045061)2.50732657
56focal adhesion assembly (GO:0048041)2.48963071
57cell-substrate adherens junction assembly (GO:0007045)2.48963071
58positive thymic T cell selection (GO:0045059)2.48506956
59modulation by virus of host process (GO:0019054)2.47957037
60T cell apoptotic process (GO:0070231)2.47567383
61UV protection (GO:0009650)2.46975070
62translational elongation (GO:0006414)2.45831209
63vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.45730196
64retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.45043613
65positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.44619694
66regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.44508833
67leukocyte aggregation (GO:0070486)2.44468357
68protein localization to chromosome, centromeric region (GO:0071459)2.44155442
69hyaluronan catabolic process (GO:0030214)2.42928000
70maternal placenta development (GO:0001893)2.42754816
71activation of JUN kinase activity (GO:0007257)2.42150021
72regulation of ARF GTPase activity (GO:0032312)2.40953333
73tooth mineralization (GO:0034505)2.39682375
74regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.39252990
753-UTR-mediated mRNA stabilization (GO:0070935)2.39084383
76protein retention in ER lumen (GO:0006621)2.38774529
77regulation of dendritic cell antigen processing and presentation (GO:0002604)2.38407440
78response to type I interferon (GO:0034340)2.37797495
79type I interferon signaling pathway (GO:0060337)2.37767203
80cellular response to type I interferon (GO:0071357)2.37767203
81regulation of extracellular matrix organization (GO:1903053)2.37450126
82detection of external biotic stimulus (GO:0098581)2.37210295
83telomere maintenance via semi-conservative replication (GO:0032201)2.36993899
84planar cell polarity pathway involved in neural tube closure (GO:0090179)2.36642397
85DNA strand elongation (GO:0022616)2.36105171
86maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.35427783
87SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.35320457
88formation of translation preinitiation complex (GO:0001731)2.34989737
89low-density lipoprotein particle clearance (GO:0034383)2.34918266
90positive regulation of endothelial cell apoptotic process (GO:2000353)2.34756392
91regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.34305370
92amyloid precursor protein catabolic process (GO:0042987)2.33487355
93peptidyl-proline hydroxylation (GO:0019511)2.33110063
94signal complex assembly (GO:0007172)2.33021890
95cell migration involved in heart development (GO:0060973)2.32950119
96fibril organization (GO:0097435)2.32048422
97lipopolysaccharide-mediated signaling pathway (GO:0031663)2.30869246
98activation of Rac GTPase activity (GO:0032863)2.30836155
99regulation of translational fidelity (GO:0006450)2.30804632
100positive regulation of gamma-delta T cell activation (GO:0046645)2.30731697
101ribosomal small subunit assembly (GO:0000028)2.30359197
102NADPH regeneration (GO:0006740)2.29994580
103protein targeting to ER (GO:0045047)2.29926056
104cotranslational protein targeting to membrane (GO:0006613)2.28704085
105negative regulation of fatty acid transport (GO:2000192)2.28381859
106collagen fibril organization (GO:0030199)2.28043768
107cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.27900853
108positive regulation of protein dephosphorylation (GO:0035307)2.27894307
109cell-cell junction maintenance (GO:0045217)2.27189753
110regulation of T-helper 2 cell differentiation (GO:0045628)2.26759918
111negative regulation of viral release from host cell (GO:1902187)2.26718892
112regulation of interferon-beta biosynthetic process (GO:0045357)2.26057670
113lymphocyte apoptotic process (GO:0070227)2.25675456
114cellular hyperosmotic response (GO:0071474)2.25152562
115L-serine metabolic process (GO:0006563)2.24814565
116regulation of apoptotic process involved in morphogenesis (GO:1902337)2.24640349
117activation of MAPKKK activity (GO:0000185)2.23923450
118mitotic chromosome condensation (GO:0007076)2.23143897
119regulation of interleukin-12 biosynthetic process (GO:0045075)2.22991583
120substrate adhesion-dependent cell spreading (GO:0034446)2.22933262
121wound healing, spreading of epidermal cells (GO:0035313)2.22209314
122blood vessel maturation (GO:0001955)2.21120570
123mitotic nuclear envelope disassembly (GO:0007077)2.20848570
124embryonic process involved in female pregnancy (GO:0060136)2.20767385
125translational initiation (GO:0006413)2.20028744
126germinal center formation (GO:0002467)2.19745699
127positive regulation of protein deacetylation (GO:0090312)2.19464877
128positive regulation of natural killer cell differentiation (GO:0032825)2.19357271
1294-hydroxyproline metabolic process (GO:0019471)2.19141218
130establishment of protein localization to endoplasmic reticulum (GO:0072599)2.18725374
131histone-serine phosphorylation (GO:0035404)2.18716944
132negative regulation of innate immune response (GO:0045824)2.17178550
133regulation of leukocyte degranulation (GO:0043300)2.16954826
134myeloid cell homeostasis (GO:0002262)2.16165420
135mitotic sister chromatid segregation (GO:0000070)2.15070114
136positive regulation of epithelial to mesenchymal transition (GO:0010718)2.15048445
137ribosomal small subunit biogenesis (GO:0042274)2.14799030
138hemidesmosome assembly (GO:0031581)2.14783250
139activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.14113458
140nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.13621219
141response to fluid shear stress (GO:0034405)2.13512721
142wound healing, spreading of cells (GO:0044319)2.13419325
143retrograde transport, endosome to Golgi (GO:0042147)2.13390161
144viral life cycle (GO:0019058)2.12635868
145COPI coating of Golgi vesicle (GO:0048205)2.12165542
146Golgi transport vesicle coating (GO:0048200)2.12165542
147regulation of spindle organization (GO:0090224)2.11968168
148adhesion of symbiont to host (GO:0044406)2.11177973
149cell adhesion mediated by integrin (GO:0033627)2.10826999
150regulation of tight junction assembly (GO:2000810)2.08879172
151endothelial cell morphogenesis (GO:0001886)2.08763512
152protein localization to endoplasmic reticulum (GO:0070972)2.08395827
153heterochromatin organization (GO:0070828)2.06936854
154regulation of mitotic spindle organization (GO:0060236)2.06782405
155renal filtration (GO:0097205)2.06196581
156atrioventricular valve morphogenesis (GO:0003181)2.05153303
157positive regulation of blood vessel endothelial cell migration (GO:0043536)2.04478573
158IMP biosynthetic process (GO:0006188)2.04452706
159pinocytosis (GO:0006907)2.04122593
160DNA replication initiation (GO:0006270)2.04021568
161positive regulation of nuclease activity (GO:0032075)2.03509372
162tetrahydrofolate metabolic process (GO:0046653)2.00906347
163antigen processing and presentation via MHC class Ib (GO:0002475)2.00815465
164barbed-end actin filament capping (GO:0051016)2.00753917
165polarized epithelial cell differentiation (GO:0030859)2.00557463
166epithelial cell-cell adhesion (GO:0090136)1.98914475
167cellular response to interferon-alpha (GO:0035457)1.98775377
168glomerular filtration (GO:0003094)1.97508807
169pteridine-containing compound biosynthetic process (GO:0042559)1.97246789
170platelet aggregation (GO:0070527)1.96765384
171cellular protein complex disassembly (GO:0043624)1.96657911
172regulation of type I interferon-mediated signaling pathway (GO:0060338)1.95985657
173regulation of integrin activation (GO:0033623)1.95930662
174negative regulation of smooth muscle cell migration (GO:0014912)1.95810723
175negative regulation of erythrocyte differentiation (GO:0045647)1.95472452

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.28213365
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.31571440
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.00086284
4TP63_17297297_ChIP-ChIP_HaCaT_Human2.57363616
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.36263177
6MYC_22102868_ChIP-Seq_BL_Human2.36229066
7RARG_19884340_ChIP-ChIP_MEFs_Mouse2.25383179
8VDR_21846776_ChIP-Seq_THP-1_Human2.23952890
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.18473565
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.14723669
11ELK3_25401928_ChIP-Seq_HUVEC_Human2.13671156
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.98994563
13TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91508013
14MYC_18555785_ChIP-Seq_MESCs_Mouse1.91021800
15TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.79176783
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.76709962
17NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.76270291
18CLOCK_20551151_ChIP-Seq_293T_Human1.75737812
19* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71815129
20TRIM28_21343339_ChIP-Seq_HEK293_Human1.70701264
21KDM2B_26808549_Chip-Seq_K562_Human1.69505478
22AR_21909140_ChIP-Seq_LNCAP_Human1.69503100
23TET1_21451524_ChIP-Seq_MESCs_Mouse1.64264803
24* SA1_27219007_Chip-Seq_ERYTHROID_Human1.63739594
25RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.63437137
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.63258616
27CTCF_27219007_Chip-Seq_ERYTHROID_Human1.61958566
28MAF_26560356_Chip-Seq_TH1_Human1.60941847
29P68_20966046_ChIP-Seq_HELA_Human1.60562165
30UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.59341285
31TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.54685413
32HIF1A_21447827_ChIP-Seq_MCF-7_Human1.50998705
33KDM2B_26808549_Chip-Seq_JURKAT_Human1.48893095
34SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.48459644
35EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.48244246
36E2F4_17652178_ChIP-ChIP_JURKAT_Human1.46669918
37MYC_19079543_ChIP-ChIP_MESCs_Mouse1.46028464
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43599153
39LXR_22292898_ChIP-Seq_THP-1_Human1.43523995
40ELF1_20517297_ChIP-Seq_JURKAT_Human1.43273045
41MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.42651923
42KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41290091
43SMC4_20622854_ChIP-Seq_HELA_Human1.41019999
44UTX_26944678_Chip-Seq_JUKART_Human1.40999705
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.40559048
46BRD4_27068464_Chip-Seq_AML-cells_Mouse1.40455780
47IRF8_22096565_ChIP-ChIP_GC-B_Human1.40350268
48* TCF7_22412390_ChIP-Seq_EML_Mouse1.39838892
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.39598617
50ERG_21242973_ChIP-ChIP_JURKAT_Human1.39497825
51* XRN2_22483619_ChIP-Seq_HELA_Human1.38737805
52SRY_22984422_ChIP-ChIP_TESTIS_Rat1.38698517
53ZFP281_18757296_ChIP-ChIP_E14_Mouse1.38045224
54VDR_24763502_ChIP-Seq_THP-1_Human1.37840538
55SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.36746052
56MYC_18358816_ChIP-ChIP_MESCs_Mouse1.35970799
57BCL6_27268052_Chip-Seq_Bcells_Human1.35707203
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.35220825
59RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.35013812
60DNAJC2_21179169_ChIP-ChIP_NT2_Human1.33610227
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.33604910
62MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.32319099
63MYB_21317192_ChIP-Seq_ERMYB_Mouse1.31976685
64BCOR_27268052_Chip-Seq_Bcells_Human1.31756874
65TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31575919
66PPARA_22158963_ChIP-Seq_LIVER_Mouse1.30650828
67KDM2B_26808549_Chip-Seq_DND41_Human1.30212444
68PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.29284408
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.29113134
70SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.28742041
71ATF3_27146783_Chip-Seq_COLON_Human1.27520367
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27272146
73TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25633033
74RACK7_27058665_Chip-Seq_MCF-7_Human1.25007796
75SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.24364257
76ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.24236448
77KDM2B_26808549_Chip-Seq_SUP-B15_Human1.23265670
78KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22840140
79HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.22491396
80CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.21906395
81SCL_19346495_ChIP-Seq_HPC-7_Human1.21282069
82STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.20460873
83TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.20217603
84ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.19917054
85CREB1_26743006_Chip-Seq_LNCaP_Human1.18820501
86BP1_19119308_ChIP-ChIP_Hs578T_Human1.17912094
87NELFA_20434984_ChIP-Seq_ESCs_Mouse1.17664279
88MYC_19030024_ChIP-ChIP_MESCs_Mouse1.17260494
89KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17005634
90MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.16804047
91FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.15288107
92MAF_26560356_Chip-Seq_TH2_Human1.14182244
93ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.14112423
94CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.13764273
95GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13378588
96TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.12435953
97RUNX1_22412390_ChIP-Seq_EML_Mouse1.12420306
98NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.12207768
99MYB_26560356_Chip-Seq_TH2_Human1.11949473
100GATA1_19941827_ChIP-Seq_MEL_Mouse1.11910584
101KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10923529
102NCOR1_26117541_ChIP-Seq_K562_Human1.10623391
103NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.10261584
104* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.09982004
105WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09268320
106MYB_26560356_Chip-Seq_TH1_Human1.09266036
107CTCF_27219007_Chip-Seq_Bcells_Human1.08988917
108CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08056204
109THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07950540
110RXR_22158963_ChIP-Seq_LIVER_Mouse1.07691755
111SMC1_22415368_ChIP-Seq_MEFs_Mouse1.07166888
112CTCF_26484167_Chip-Seq_Bcells_Mouse1.07017668
113SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06376734
114SPI1_23127762_ChIP-Seq_K562_Human1.06339532
115SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.06071331
116PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05767097
117SPI1_23547873_ChIP-Seq_NB4_Human1.05702973
118DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.05452676
119CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05142286
120PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05055429
121SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.04912618
122STAT4_19710469_ChIP-ChIP_TH1__Mouse1.04765605
123VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04641702
124FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03333725
125IRF8_21731497_ChIP-ChIP_J774_Mouse1.03253431
126TFEB_21752829_ChIP-Seq_HELA_Human1.03202997
127* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02796803
128E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.02407532
129E2F1_18555785_ChIP-Seq_MESCs_Mouse1.00905577
130TP53_22127205_ChIP-Seq_IMR90_Human0.99943557
131IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.99579422
132KLF4_18555785_ChIP-Seq_MESCs_Mouse0.99243747
133STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.99116146
134CIITA_25753668_ChIP-Seq_RAJI_Human0.99020262
135TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97619817
136MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.96675878
137ZNF263_19887448_ChIP-Seq_K562_Human0.96606598
138P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96512749
139SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.95742383
140CREB1_15753290_ChIP-ChIP_HEK293T_Human0.94696768
141KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.93631386
142CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.92355008
143DCP1A_22483619_ChIP-Seq_HELA_Human0.92101152
144POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91882201
145E2F1_21310950_ChIP-Seq_MCF-7_Human0.90723875

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.02464913
2MP0003705_abnormal_hypodermis_morpholog3.09224931
3MP0008260_abnormal_autophagy2.64174577
4MP0003279_aneurysm2.57190486
5MP0006054_spinal_hemorrhage2.49765609
6MP0003172_abnormal_lysosome_physiology2.45706007
7MP0003191_abnormal_cellular_cholesterol2.30986005
8MP0005451_abnormal_body_composition2.20027917
9MP0001849_ear_inflammation2.08526628
10MP0003566_abnormal_cell_adhesion1.99452254
11MP0004858_abnormal_nervous_system1.98528708
12MP0005023_abnormal_wound_healing1.96599335
13MP0005275_abnormal_skin_tensile1.88073216
14MP0004272_abnormal_basement_membrane1.84463729
15MP0010368_abnormal_lymphatic_system1.78670124
16MP0009840_abnormal_foam_cell1.75436620
17MP0001958_emphysema1.72002503
18MP0000685_abnormal_immune_system1.71757219
19MP0005257_abnormal_intraocular_pressure1.70855117
20MP0004510_myositis1.67321702
21MP0002396_abnormal_hematopoietic_system1.63459659
22MP0010352_gastrointestinal_tract_polyps1.59860415
23MP0003300_gastrointestinal_ulcer1.57609447
24MP0005503_abnormal_tendon_morphology1.57432953
25MP0009278_abnormal_bone_marrow1.50235597
26MP0005623_abnormal_meninges_morphology1.46801434
27MP0003453_abnormal_keratinocyte_physiol1.46404222
28MP0005076_abnormal_cell_differentiation1.41082521
29MP0008007_abnormal_cellular_replicative1.40267543
30MP0001348_abnormal_lacrimal_gland1.38803656
31MP0002998_abnormal_bone_remodeling1.38491188
32MP0009333_abnormal_splenocyte_physiolog1.35983740
33MP0009384_cardiac_valve_regurgitation1.34114068
34MP0004808_abnormal_hematopoietic_stem1.33344442
35MP0005360_urolithiasis1.33338980
36MP0005409_darkened_coat_color1.33202459
37MP0002877_abnormal_melanocyte_morpholog1.33197921
38MP0003436_decreased_susceptibility_to1.33117891
39MP0010030_abnormal_orbit_morphology1.30437539
40MP0003091_abnormal_cell_migration1.27199309
41MP0000733_abnormal_muscle_development1.23751418
42MP0003077_abnormal_cell_cycle1.23351598
43MP0002933_joint_inflammation1.23339348
44MP0001243_abnormal_dermal_layer1.23134450
45MP0000678_abnormal_parathyroid_gland1.20555777
46MP0000858_altered_metastatic_potential1.17916014
47MP0001545_abnormal_hematopoietic_system1.17531109
48MP0005397_hematopoietic_system_phenotyp1.17531109
49MP0000767_abnormal_smooth_muscle1.17478462
50MP0000751_myopathy1.16824422
51MP0003448_altered_tumor_morphology1.15906045
52MP0010307_abnormal_tumor_latency1.15681741
53MP0003075_altered_response_to1.14719373
54MP0000343_altered_response_to1.13090335
55MP0001533_abnormal_skeleton_physiology1.11044243
56MP0001915_intracranial_hemorrhage1.10355021
57MP0000750_abnormal_muscle_regeneration1.10227314
58MP0002060_abnormal_skin_morphology1.09997264
59MP0005375_adipose_tissue_phenotype1.09713094
60MP0003329_amyloid_beta_deposits1.09684866
61MP0000003_abnormal_adipose_tissue1.08952831
62MP0001853_heart_inflammation1.08516542
63MP0005666_abnormal_adipose_tissue1.08363607
64MP0003303_peritoneal_inflammation1.08028190
65MP0002148_abnormal_hypersensitivity_rea1.07817756
66MP0002405_respiratory_system_inflammati1.07486245
67MP0004957_abnormal_blastocyst_morpholog1.07190016
68MP0003828_pulmonary_edema1.06322965
69MP0001879_abnormal_lymphatic_vessel1.06128562
70MP0000604_amyloidosis1.05812532
71MP0004947_skin_inflammation1.05528079
72MP0003724_increased_susceptibility_to1.05386885
73MP0005083_abnormal_biliary_tract1.04491852
74MP0003111_abnormal_nucleus_morphology1.04164550
75MP0001873_stomach_inflammation1.04073216
76MP0000465_gastrointestinal_hemorrhage1.02914879
77MP0001790_abnormal_immune_system1.02427955
78MP0005387_immune_system_phenotype1.02427955
79MP0005058_abnormal_lysosome_morphology1.01087178
80MP0005508_abnormal_skeleton_morphology0.98798482
81MP0003656_abnormal_erythrocyte_physiolo0.98722520
82MP0005671_abnormal_response_to0.98114521
83MP0003806_abnormal_nucleotide_metabolis0.97937982
84MP0001730_embryonic_growth_arrest0.96910260
85MP0002254_reproductive_system_inflammat0.96522779
86MP0003693_abnormal_embryo_hatching0.96255312
87MP0000490_abnormal_crypts_of0.95776559
88MP0002249_abnormal_larynx_morphology0.95365896
89MP0003183_abnormal_peptide_metabolism0.93197908
90MP0001800_abnormal_humoral_immune0.93061580
91MP0010094_abnormal_chromosome_stability0.92427426
92MP0005390_skeleton_phenotype0.92264468
93MP0002452_abnormal_antigen_presenting0.92258524
94MP0002722_abnormal_immune_system0.91793090
95MP0002398_abnormal_bone_marrow0.91659213
96MP0004084_abnormal_cardiac_muscle0.91578030
97MP0002128_abnormal_blood_circulation0.90472491
98MP0000689_abnormal_spleen_morphology0.90450548
99MP0005166_decreased_susceptibility_to0.90052184
100MP0001845_abnormal_inflammatory_respons0.89155748
101MP0005025_abnormal_response_to0.88125845
102MP0000350_abnormal_cell_proliferation0.87727517
103MP0010630_abnormal_cardiac_muscle0.86874655
104MP0001614_abnormal_blood_vessel0.86255112
105MP0004381_abnormal_hair_follicle0.85865693
106MP0000716_abnormal_immune_system0.85750877
107MP0005464_abnormal_platelet_physiology0.85453418
108MP0003795_abnormal_bone_structure0.85110299
109MP0006082_CNS_inflammation0.84805663
110MP0005670_abnormal_white_adipose0.84725489
111MP0001835_abnormal_antigen_presentation0.84124351
112MP0002089_abnormal_postnatal_growth/wei0.83693124
113MP0008469_abnormal_protein_level0.83362207
114MP0005000_abnormal_immune_tolerance0.83235401
115MP0002419_abnormal_innate_immunity0.82297199
116MP0009785_altered_susceptibility_to0.82083427
117MP0002925_abnormal_cardiovascular_devel0.81529125
118MP0003984_embryonic_growth_retardation0.80959921
119MP0000703_abnormal_thymus_morphology0.80730187
120MP0001851_eye_inflammation0.80624001
121MP0003763_abnormal_thymus_physiology0.80505277
122MP0002088_abnormal_embryonic_growth/wei0.80396585
123MP0002723_abnormal_immune_serum0.79546343
124MP0002429_abnormal_blood_cell0.79362685
125MP0004197_abnormal_fetal_growth/weight/0.79032120
126MP0002420_abnormal_adaptive_immunity0.79026974
127MP0001697_abnormal_embryo_size0.78978661
128MP0010155_abnormal_intestine_physiology0.78726182
129MP0001542_abnormal_bone_strength0.78534798
130MP0001819_abnormal_immune_cell0.78475079
131MP0000249_abnormal_blood_vessel0.77420494
132MP0002086_abnormal_extraembryonic_tissu0.76140675
133MP0000681_abnormal_thyroid_gland0.76140428
134MP0004185_abnormal_adipocyte_glucose0.75533318
135MP0005164_abnormal_response_to0.75104590
136MP0000598_abnormal_liver_morphology0.74849605
137MP0002080_prenatal_lethality0.74142996

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.85949756
2Premature rupture of membranes (HP:0001788)5.34670405
3Peritonitis (HP:0002586)3.55422595
4Ankle contracture (HP:0006466)3.54346412
5Shallow orbits (HP:0000586)3.51624529
6Cerebral aneurysm (HP:0004944)3.48071469
7Aortic dissection (HP:0002647)3.13331264
8Vertebral compression fractures (HP:0002953)3.08823290
9Dysostosis multiplex (HP:0000943)3.02163047
10Eczematoid dermatitis (HP:0000976)2.87468431
11Nonimmune hydrops fetalis (HP:0001790)2.84727527
12Biconcave vertebral bodies (HP:0004586)2.84211284
13Soft skin (HP:0000977)2.78441738
14Cervical subluxation (HP:0003308)2.78048528
15Broad metatarsal (HP:0001783)2.77847211
16Obstructive sleep apnea (HP:0002870)2.73548337
17Ulnar bowing (HP:0003031)2.68169689
18Increased connective tissue (HP:0009025)2.65384457
19Achilles tendon contracture (HP:0001771)2.59022302
20Blue sclerae (HP:0000592)2.58187563
21Aortic aneurysm (HP:0004942)2.57775019
22Broad face (HP:0000283)2.54563000
23Bladder diverticulum (HP:0000015)2.50233090
24Abnormality of glycolipid metabolism (HP:0010969)2.49442563
25Abnormality of liposaccharide metabolism (HP:0010968)2.49442563
26Abnormality of glycosphingolipid metabolism (HP:0004343)2.49442563
27Osteolytic defects of the phalanges of the hand (HP:0009771)2.45070443
28Osteolytic defects of the hand bones (HP:0009699)2.45070443
29Abnormality of mucopolysaccharide metabolism (HP:0011020)2.44813085
30Abnormality of polysaccharide metabolism (HP:0011012)2.44813085
31Abnormality of glycosaminoglycan metabolism (HP:0004371)2.44813085
32Selective tooth agenesis (HP:0001592)2.43436866
33Mucopolysacchariduria (HP:0008155)2.43128914
34Urinary glycosaminoglycan excretion (HP:0003541)2.43128914
35Spinal rigidity (HP:0003306)2.42115102
36Abnormality of the peritoneum (HP:0002585)2.41982917
37Systemic lupus erythematosus (HP:0002725)2.40584979
38Abnormality of macrophages (HP:0004311)2.38104096
39Abnormality of the Achilles tendon (HP:0005109)2.37015634
40Dilatation of the ascending aorta (HP:0005111)2.36940152
41Atrophic scars (HP:0001075)2.35882505
42Abnormality of the nasal mucosa (HP:0000433)2.31932616
43Wormian bones (HP:0002645)2.30711795
44Mitral regurgitation (HP:0001653)2.27354015
45J-shaped sella turcica (HP:0002680)2.26356012
46Distal lower limb amyotrophy (HP:0008944)2.25986003
47Abnormality of the acetabulum (HP:0003170)2.21745050
48Hemorrhage of the eye (HP:0011885)2.19281266
49Fragile skin (HP:0001030)2.16872112
50Disproportionate tall stature (HP:0001519)2.15487798
51Loss of speech (HP:0002371)2.14572921
52Increased density of long bones (HP:0006392)2.13731678
53Genu recurvatum (HP:0002816)2.13339310
54Hyperacusis (HP:0010780)2.11514956
55Distal lower limb muscle weakness (HP:0009053)2.11042180
56Mitral valve prolapse (HP:0001634)2.10788038
57Mesangial abnormality (HP:0001966)2.09205494
58Spondylolisthesis (HP:0003302)2.07436519
59Nuclear cataract (HP:0100018)2.06730877
60Bowed forearm bones (HP:0003956)2.06497840
61Bowing of the arm (HP:0006488)2.06497840
62Increased mean platelet volume (HP:0011877)2.03478569
63Coxa vara (HP:0002812)2.03091797
64Abnormality of the calcaneus (HP:0008364)2.02968702
65Hypertriglyceridemia (HP:0002155)2.01910091
66Myositis (HP:0100614)2.01738062
67Aneurysm (HP:0002617)2.01640513
68Generalized amyotrophy (HP:0003700)2.01110610
69Neonatal short-limb short stature (HP:0008921)2.00187769
70High pitched voice (HP:0001620)1.99726049
71Metaphyseal cupping (HP:0003021)1.99696123
72Polycythemia (HP:0001901)1.98217722
73Short 4th metacarpal (HP:0010044)1.98018141
74Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.98018141
75Radial bowing (HP:0002986)1.96164740
76Abnormal platelet volume (HP:0011876)1.96119168
77Mildly elevated creatine phosphokinase (HP:0008180)1.95598459
78Increased IgE level (HP:0003212)1.95440317
79Recurrent abscess formation (HP:0002722)1.94127473
80Ectopia lentis (HP:0001083)1.94008047
81Premature skin wrinkling (HP:0100678)1.93934283
82Aortic regurgitation (HP:0001659)1.93030973
83Type 1 muscle fiber predominance (HP:0003803)1.91609207
84Thin bony cortex (HP:0002753)1.91440489
85Abnormality of the umbilical cord (HP:0010881)1.90599875
86Abnormality of dentin (HP:0010299)1.90599245
87Recurrent bacterial skin infections (HP:0005406)1.90047746
88Cellulitis (HP:0100658)1.89864092
89Nasal polyposis (HP:0100582)1.89466576
90Abnormality of complement system (HP:0005339)1.88820646
91Chronic otitis media (HP:0000389)1.88498078
92Slender build (HP:0001533)1.88462230
93Long palpebral fissure (HP:0000637)1.88438184
94Increased serum ferritin (HP:0003281)1.88340490
95Axonal loss (HP:0003447)1.86591718
96Distal upper limb amyotrophy (HP:0007149)1.86234416
97Upper limb amyotrophy (HP:0009129)1.86234416
98Polygenic inheritance (HP:0010982)1.85828906
99Elbow flexion contracture (HP:0002987)1.85076891
100Trismus (HP:0000211)1.85007499
101Asymmetric septal hypertrophy (HP:0001670)1.83239473
102Increased cerebral lipofuscin (HP:0011813)1.83195803
103Joint stiffness (HP:0001387)1.82959909
104Joint laxity (HP:0001388)1.82861383
105Interstitial pulmonary disease (HP:0006530)1.81840980
106Elevated erythrocyte sedimentation rate (HP:0003565)1.80583173
107Platyspondyly (HP:0000926)1.80019219
108Abnormality of the thoracic spine (HP:0100711)1.79197122
109Vascular tortuosity (HP:0004948)1.78710561
110Chronic obstructive pulmonary disease (HP:0006510)1.78671181
111Obstructive lung disease (HP:0006536)1.78671181
112Amyloidosis (HP:0011034)1.77751834
113Reticulocytopenia (HP:0001896)1.77365019
114Stridor (HP:0010307)1.77346306
115Colitis (HP:0002583)1.77328612
116Malnutrition (HP:0004395)1.77135257
117Difficulty climbing stairs (HP:0003551)1.76829234
118Gingivitis (HP:0000230)1.75142400
119Easy fatigability (HP:0003388)1.71980871
120Abnormal delivery (HP:0001787)1.70287318
121Orchitis (HP:0100796)1.69662830
122Supranuclear gaze palsy (HP:0000605)1.68709805
123Hypertensive crisis (HP:0100735)1.67752593
124Hallux valgus (HP:0001822)1.66770132
125Deviation of the hallux (HP:0010051)1.66441206
126Recurrent gram-negative bacterial infections (HP:0005420)1.66246119
127Gastrointestinal dysmotility (HP:0002579)1.65211147
128Slender long bone (HP:0003100)1.64999931
129Beaking of vertebral bodies (HP:0004568)1.63209930
130Camptodactyly of toe (HP:0001836)1.63163765
131Emphysema (HP:0002097)1.61914291
132Wrist flexion contracture (HP:0001239)1.59762584
133Hand muscle atrophy (HP:0009130)1.59712873
134Abnormality of the 4th metacarpal (HP:0010012)1.58991489
135Breech presentation (HP:0001623)1.58670992
136Flat acetabular roof (HP:0003180)1.57632783
137Muscle fiber splitting (HP:0003555)1.57602300
138Wide anterior fontanel (HP:0000260)1.57283463
139Diaphragmatic weakness (HP:0009113)1.55633437
140Purpura (HP:0000979)1.54357133
141Calcaneovalgus deformity (HP:0001848)1.54178633
142Abnormality of iron homeostasis (HP:0011031)1.53705963
143Lymphangioma (HP:0100764)1.51553232
144Tibial bowing (HP:0002982)1.51205769
145Bowel diverticulosis (HP:0005222)1.50920841
146Deep venous thrombosis (HP:0002625)1.50614157
147Increased variability in muscle fiber diameter (HP:0003557)1.50468113
148Hematochezia (HP:0002573)1.49857478
149Hyperextensible skin (HP:0000974)1.49381497
150Thrombocytosis (HP:0001894)1.49075841
151Spontaneous hematomas (HP:0007420)1.49010139
152Deviation of the thumb (HP:0009603)1.48041109
153Petechiae (HP:0000967)1.47929102
154Abnormality of skeletal muscle fiber size (HP:0012084)1.47148537

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.94474091
2PRPF4B3.22917660
3ERN13.18177553
4EEF2K2.91841258
5SMG12.55518349
6KDR2.48766781
7TTN2.46733872
8PKN22.45563509
9MAP4K12.32041481
10TESK22.31716440
11STK102.20978933
12SIK12.14846724
13MAP3K102.08351184
14LRRK22.00076780
15NME21.95132266
16IRAK31.88028062
17EPHB11.84893307
18BUB11.81268887
19NEK21.66104270
20TYK21.63911664
21TAOK21.63635057
22TGFBR21.62360153
23IRAK41.52819419
24RPS6KA41.49683021
25CDC42BPA1.45418227
26JAK31.44086936
27TESK11.43941193
28PAK41.43292412
29MAP3K131.36262402
30PIM21.31849733
31PDGFRA1.31122418
32TGFBR11.30593297
33KIT1.29445504
34PTK61.27875060
35ZAP701.27478019
36TBK11.25488440
37MAP2K31.25152233
38FGFR41.24940013
39MAP3K61.21605104
40BMX1.21287682
41CDK121.15821416
42PAK21.13165455
43MARK21.12197587
44BCKDK1.12016988
45TNK21.10340566
46RIPK41.09568805
47MAP3K81.08850103
48TRPM71.06458347
49ICK1.04544298
50WEE11.03846558
51BLK1.01854649
52MAP3K141.01107456
53TIE11.00903080
54MST1R1.00890144
55STK40.99704386
56MAP3K10.97356312
57RPS6KA20.96272914
58FLT30.94477315
59MTOR0.94195073
60CSF1R0.93582757
61RPS6KB20.91047536
62EIF2AK10.89912588
63CDC70.89110529
64MET0.89069766
65BTK0.88587964
66ILK0.87813655
67EPHB20.87525273
68PDPK10.87050386
69PRKD30.86367547
70ARAF0.85382552
71SIK30.85134722
72CDK70.84061352
73DDR20.82454565
74MAP3K110.80221193
75CDK40.79341485
76TLK10.78594285
77HIPK20.77667655
78RPS6KL10.76595114
79RPS6KC10.76595114
80MAPKAPK30.76348356
81PTK20.75165001
82STK380.74580682
83PBK0.71033403
84FES0.70908333
85MAP3K30.70831275
86KSR20.70722778
87RIPK10.70684232
88SIK20.70606438
89MAP2K20.70585374
90MAPK120.68637164
91PAK10.67485372
92CDK60.67412063
93IKBKB0.66426647
94EPHA20.65941835
95MAPK70.65397934
96DYRK1B0.65183794
97CSK0.63677788
98EPHA30.63649005
99MAP3K70.62926861
100AURKB0.62429195
101PIM10.62119650
102ITK0.60581749
103DMPK0.60058544
104CHUK0.58939104
105STK30.57507384
106LMTK20.55901939
107RPS6KA60.55528126
108BRAF0.54641357
109TYRO30.54616913
110ABL20.52946702
111BRSK20.52546881
112MAPKAPK20.51915998
113PDK10.51365949
114MYLK0.51327482
115IKBKE0.50831290
116LATS20.50498102
117MAPK110.49945976
118MAPK150.49820335
119LIMK10.49020946
120CAMKK10.48496318
121PDGFRB0.46822231
122TAOK10.46108203
123NTRK10.45382272
124RET0.44732796
125MAP2K60.44539591
126LCK0.43721636
127MOS0.43626851
128HCK0.42403660
129PASK0.42357313
130PRKD10.41959183
131GRK60.41414753
132MAPK40.41338606
133NEK90.40702863
134PLK10.40630380
135JAK10.40538956
136PRKG20.37901141
137PTK2B0.37652617
138ATR0.36274861
139TTK0.33471366
140PRKD20.28867549
141BRSK10.28405577
142MARK30.28215282

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.76490379
2One carbon pool by folate_Homo sapiens_hsa006701.89845090
3ECM-receptor interaction_Homo sapiens_hsa045121.84174898
4Ribosome_Homo sapiens_hsa030101.79818262
5Small cell lung cancer_Homo sapiens_hsa052221.73064732
6Mismatch repair_Homo sapiens_hsa034301.73037626
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.58527012
8Malaria_Homo sapiens_hsa051441.55885175
9Base excision repair_Homo sapiens_hsa034101.52704405
10Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.44158582
11Cell cycle_Homo sapiens_hsa041101.40913764
12VEGF signaling pathway_Homo sapiens_hsa043701.40862439
13Prion diseases_Homo sapiens_hsa050201.36315885
14p53 signaling pathway_Homo sapiens_hsa041151.34074679
15Antigen processing and presentation_Homo sapiens_hsa046121.32379161
16Focal adhesion_Homo sapiens_hsa045101.31850333
17Cyanoamino acid metabolism_Homo sapiens_hsa004601.29590098
18Non-small cell lung cancer_Homo sapiens_hsa052231.29564124
19Leishmaniasis_Homo sapiens_hsa051401.26615568
20Viral myocarditis_Homo sapiens_hsa054161.26084549
21Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.25092582
22Galactose metabolism_Homo sapiens_hsa000521.21651733
23Bladder cancer_Homo sapiens_hsa052191.21362977
24Chronic myeloid leukemia_Homo sapiens_hsa052201.21258516
25Toxoplasmosis_Homo sapiens_hsa051451.20081472
26Pentose phosphate pathway_Homo sapiens_hsa000301.19595053
27Shigellosis_Homo sapiens_hsa051311.19353883
28Tuberculosis_Homo sapiens_hsa051521.16272039
29Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.16124490
30Leukocyte transendothelial migration_Homo sapiens_hsa046701.14815139
31Measles_Homo sapiens_hsa051621.14788834
32Neurotrophin signaling pathway_Homo sapiens_hsa047221.13476210
33Primary immunodeficiency_Homo sapiens_hsa053401.13256046
34Hepatitis C_Homo sapiens_hsa051601.12238538
35Fructose and mannose metabolism_Homo sapiens_hsa000511.11697193
36RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.11595196
37Notch signaling pathway_Homo sapiens_hsa043301.11576805
38Apoptosis_Homo sapiens_hsa042101.11454386
39Sulfur relay system_Homo sapiens_hsa041221.10346971
40AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.10302405
41Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.04943129
42HTLV-I infection_Homo sapiens_hsa051661.04781404
43Spliceosome_Homo sapiens_hsa030401.04424763
44Glycosaminoglycan degradation_Homo sapiens_hsa005311.03819402
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.03649369
46Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02433966
47Proteoglycans in cancer_Homo sapiens_hsa052051.00722129
48Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00570977
49Staphylococcus aureus infection_Homo sapiens_hsa051501.00369532
50Legionellosis_Homo sapiens_hsa051341.00071193
51Protein digestion and absorption_Homo sapiens_hsa049740.99696230
52Biosynthesis of amino acids_Homo sapiens_hsa012300.99517250
53Other glycan degradation_Homo sapiens_hsa005110.99419956
54Viral carcinogenesis_Homo sapiens_hsa052030.99295190
55NF-kappa B signaling pathway_Homo sapiens_hsa040640.98065581
56Salmonella infection_Homo sapiens_hsa051320.97964693
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.97618956
58MicroRNAs in cancer_Homo sapiens_hsa052060.97024857
59Allograft rejection_Homo sapiens_hsa053300.96512271
60Endocytosis_Homo sapiens_hsa041440.96341817
61Fatty acid degradation_Homo sapiens_hsa000710.95472023
62Selenocompound metabolism_Homo sapiens_hsa004500.94991992
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.94891895
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.94087878
65Homologous recombination_Homo sapiens_hsa034400.93095321
66Herpes simplex infection_Homo sapiens_hsa051680.92728078
67Lysine degradation_Homo sapiens_hsa003100.92503169
68T cell receptor signaling pathway_Homo sapiens_hsa046600.89705644
69RNA transport_Homo sapiens_hsa030130.89619186
70Pancreatic cancer_Homo sapiens_hsa052120.89013908
71Folate biosynthesis_Homo sapiens_hsa007900.88411697
72Autoimmune thyroid disease_Homo sapiens_hsa053200.88334355
73Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.87579792
74Graft-versus-host disease_Homo sapiens_hsa053320.87328361
75Amoebiasis_Homo sapiens_hsa051460.86950985
76Phagosome_Homo sapiens_hsa041450.86050872
77Hepatitis B_Homo sapiens_hsa051610.85708063
78Osteoclast differentiation_Homo sapiens_hsa043800.85658815
79Chemokine signaling pathway_Homo sapiens_hsa040620.84346058
80Carbon metabolism_Homo sapiens_hsa012000.84047982
81Endometrial cancer_Homo sapiens_hsa052130.83154421
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.81590320
83B cell receptor signaling pathway_Homo sapiens_hsa046620.81400235
84Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81382710
852-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80667084
86GnRH signaling pathway_Homo sapiens_hsa049120.80277952
87Glioma_Homo sapiens_hsa052140.80194956
88Nucleotide excision repair_Homo sapiens_hsa034200.79083402
89Hematopoietic cell lineage_Homo sapiens_hsa046400.78866085
90Pertussis_Homo sapiens_hsa051330.78551955
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76363856
92Renal cell carcinoma_Homo sapiens_hsa052110.76323170
93Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.75714293
94Adherens junction_Homo sapiens_hsa045200.74473989
95PI3K-Akt signaling pathway_Homo sapiens_hsa041510.73360723
96Pyrimidine metabolism_Homo sapiens_hsa002400.73126512
97Fatty acid metabolism_Homo sapiens_hsa012120.73056801
98Acute myeloid leukemia_Homo sapiens_hsa052210.72573424
99Epstein-Barr virus infection_Homo sapiens_hsa051690.72319915
100Prolactin signaling pathway_Homo sapiens_hsa049170.72042023
101Lysosome_Homo sapiens_hsa041420.71001691
102Complement and coagulation cascades_Homo sapiens_hsa046100.70048217
103Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.69814441
104Insulin resistance_Homo sapiens_hsa049310.69589597
105Platelet activation_Homo sapiens_hsa046110.69289973
106Glutathione metabolism_Homo sapiens_hsa004800.69286058
107Vibrio cholerae infection_Homo sapiens_hsa051100.68544332
108Jak-STAT signaling pathway_Homo sapiens_hsa046300.68264275
109African trypanosomiasis_Homo sapiens_hsa051430.68210779
110Insulin signaling pathway_Homo sapiens_hsa049100.68203204
111mTOR signaling pathway_Homo sapiens_hsa041500.66418586
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66100212
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.65185182
114Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65119928
115Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64906669
116Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64893428
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.64511702
118Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.63140871
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.62348300
120ErbB signaling pathway_Homo sapiens_hsa040120.62177343
121Arginine and proline metabolism_Homo sapiens_hsa003300.61923349
122Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60906635
123Thyroid cancer_Homo sapiens_hsa052160.60211881
124Influenza A_Homo sapiens_hsa051640.60155332
125PPAR signaling pathway_Homo sapiens_hsa033200.59638168
126N-Glycan biosynthesis_Homo sapiens_hsa005100.59638102
127Choline metabolism in cancer_Homo sapiens_hsa052310.59551615
128Central carbon metabolism in cancer_Homo sapiens_hsa052300.59242414
129Prostate cancer_Homo sapiens_hsa052150.59025077
130Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.58525028
131Proteasome_Homo sapiens_hsa030500.57870670
132Basal cell carcinoma_Homo sapiens_hsa052170.56805399
133Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.56381081
134Non-homologous end-joining_Homo sapiens_hsa034500.55603003
135Steroid biosynthesis_Homo sapiens_hsa001000.55404651
136TNF signaling pathway_Homo sapiens_hsa046680.55369420
137Estrogen signaling pathway_Homo sapiens_hsa049150.54577013
138Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54446252
139Pathways in cancer_Homo sapiens_hsa052000.53944690
140Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53760153
141Caffeine metabolism_Homo sapiens_hsa002320.53661935
142Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53025252
143Intestinal immune network for IgA production_Homo sapiens_hsa046720.52963031
144HIF-1 signaling pathway_Homo sapiens_hsa040660.52043505
145Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.50792150
146Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.50575687
147Rap1 signaling pathway_Homo sapiens_hsa040150.50196855
148Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.49494647
149Inositol phosphate metabolism_Homo sapiens_hsa005620.48692951

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