LMNTD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)8.99127664
2acrosome reaction (GO:0007340)8.72897202
3multicellular organism reproduction (GO:0032504)8.68368476
4axonemal dynein complex assembly (GO:0070286)8.56094245
5cilium or flagellum-dependent cell motility (GO:0001539)8.20364487
6cell wall macromolecule metabolic process (GO:0044036)8.01844219
7cell wall macromolecule catabolic process (GO:0016998)8.01844219
8epithelial cilium movement (GO:0003351)7.98880786
9sperm-egg recognition (GO:0035036)7.94961942
10motile cilium assembly (GO:0044458)7.85056990
11acrosome assembly (GO:0001675)7.67406788
12cilium movement (GO:0003341)7.63885586
13cell-cell recognition (GO:0009988)7.24204975
14binding of sperm to zona pellucida (GO:0007339)7.22667545
15reproduction (GO:0000003)7.21254348
16regulation of cilium movement (GO:0003352)7.06293291
17plasma membrane fusion (GO:0045026)6.90525955
18spermatid development (GO:0007286)6.72173735
19piRNA metabolic process (GO:0034587)6.54035980
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.18538836
21single fertilization (GO:0007338)5.98040429
22sperm capacitation (GO:0048240)5.44090977
23male meiosis (GO:0007140)5.43009043
24ventricular system development (GO:0021591)5.32705462
25response to pheromone (GO:0019236)5.24504852
26synaptonemal complex organization (GO:0070193)5.21145856
27behavioral response to nicotine (GO:0035095)5.09192622
28synaptonemal complex assembly (GO:0007130)5.07850315
29spermatogenesis (GO:0007283)5.00354237
30negative regulation of inclusion body assembly (GO:0090084)5.00116889
31diterpenoid biosynthetic process (GO:0016102)4.98208405
32male gamete generation (GO:0048232)4.98163345
33fertilization (GO:0009566)4.93117869
34microtubule depolymerization (GO:0007019)4.86711300
35gamete generation (GO:0007276)4.63462241
36left/right pattern formation (GO:0060972)4.44018240
37DNA deamination (GO:0045006)4.41459491
38microtubule severing (GO:0051013)4.38725452
39fucose catabolic process (GO:0019317)4.38207229
40L-fucose metabolic process (GO:0042354)4.38207229
41L-fucose catabolic process (GO:0042355)4.38207229
42DNA methylation involved in gamete generation (GO:0043046)4.30473564
43organic cation transport (GO:0015695)4.15683426
44calcium ion-dependent exocytosis (GO:0017156)4.08835600
45somite rostral/caudal axis specification (GO:0032525)3.94503670
46cellular process involved in reproduction in multicellular organism (GO:0022412)3.88425433
47protein localization to cilium (GO:0061512)3.85268177
48myoblast migration (GO:0051451)3.84110713
49germ cell development (GO:0007281)3.83534165
50regulation of microtubule-based movement (GO:0060632)3.82598202
51cell recognition (GO:0008037)3.75891527
52multicellular organismal reproductive process (GO:0048609)3.74605877
53regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.73927033
54seminiferous tubule development (GO:0072520)3.66119728
55photoreceptor cell maintenance (GO:0045494)3.56495278
56cellular ketone body metabolic process (GO:0046950)3.53975002
57regulation of inclusion body assembly (GO:0090083)3.53822353
58regulation of mesoderm development (GO:2000380)3.51751643
59negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.51557538
60intraciliary transport (GO:0042073)3.50730671
61male meiosis I (GO:0007141)3.47906998
62platelet dense granule organization (GO:0060155)3.45900073
63cilium morphogenesis (GO:0060271)3.44784531
64left/right axis specification (GO:0070986)3.41159818
65protein K11-linked deubiquitination (GO:0035871)3.40839456
66glycerol ether metabolic process (GO:0006662)3.36099418
67retinal cone cell development (GO:0046549)3.34815726
68centriole replication (GO:0007099)3.34239155
69sulfation (GO:0051923)3.34193420
70protein polyglutamylation (GO:0018095)3.34109789
71sialylation (GO:0097503)3.33339251
72negative regulation of fatty acid transport (GO:2000192)3.32691763
73vitamin A metabolic process (GO:0006776)3.30292740
74indole-containing compound catabolic process (GO:0042436)3.28528777
75indolalkylamine catabolic process (GO:0046218)3.28528777
76tryptophan catabolic process (GO:0006569)3.28528777
77multicellular organismal development (GO:0007275)3.28116052
78establishment of protein localization to Golgi (GO:0072600)3.25204516
79ketone body metabolic process (GO:1902224)3.23330923
80terpenoid biosynthetic process (GO:0016114)3.20498346
81regulation of corticosteroid hormone secretion (GO:2000846)3.11154786
82positive regulation of macrophage activation (GO:0043032)3.11036523
83cellular anion homeostasis (GO:0030002)3.10442495
84detection of light stimulus involved in sensory perception (GO:0050962)3.09178326
85detection of light stimulus involved in visual perception (GO:0050908)3.09178326
86indolalkylamine metabolic process (GO:0006586)3.08335749
87neural tube formation (GO:0001841)3.08314244
88ether metabolic process (GO:0018904)3.02867904
89chromosome organization involved in meiosis (GO:0070192)3.01417531
90detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.01220769
91positive regulation of hormone biosynthetic process (GO:0046886)3.00052030
92retinal metabolic process (GO:0042574)2.95009484
93regulation of meiosis I (GO:0060631)2.94683113
94adaptation of signaling pathway (GO:0023058)2.94473033
95nonmotile primary cilium assembly (GO:0035058)2.94008996
96meiotic nuclear division (GO:0007126)2.93443733
97embryonic heart tube development (GO:0035050)2.93130606
98exogenous drug catabolic process (GO:0042738)2.92650804
99rhodopsin mediated signaling pathway (GO:0016056)2.91482395
100regulation of oxidative stress-induced neuron death (GO:1903203)2.88595015
101cytidine metabolic process (GO:0046087)2.87012016
102cytidine catabolic process (GO:0006216)2.87012016
103cytidine deamination (GO:0009972)2.87012016
104behavioral response to ethanol (GO:0048149)2.86750547
105kynurenine metabolic process (GO:0070189)2.86390939
106spermatid nucleus differentiation (GO:0007289)2.85572681
107positive regulation of endothelial cell differentiation (GO:0045603)2.84207039
108protein targeting to Golgi (GO:0000042)2.82652662
109regulation of hexokinase activity (GO:1903299)2.82252397
110regulation of glucokinase activity (GO:0033131)2.82252397
111negative regulation of potassium ion transmembrane transport (GO:1901380)2.81159374
112reflex (GO:0060004)2.78768269
113midgut development (GO:0007494)2.77758912
114spinal cord motor neuron differentiation (GO:0021522)2.76367611
115cellular component assembly involved in morphogenesis (GO:0010927)2.76258387
116glycosphingolipid biosynthetic process (GO:0006688)2.75891424
117cilium organization (GO:0044782)2.75732212
118neuronal action potential (GO:0019228)2.74654175
119ganglioside metabolic process (GO:0001573)2.73453770
120axoneme assembly (GO:0035082)2.73146965
121regulation of rhodopsin mediated signaling pathway (GO:0022400)2.72477684
122cilium assembly (GO:0042384)2.71834029
123type B pancreatic cell development (GO:0003323)2.70333489
124RNA destabilization (GO:0050779)2.68562487
125phosphatidylethanolamine biosynthetic process (GO:0006646)2.67616621
126amine catabolic process (GO:0009310)2.66974441
127cellular biogenic amine catabolic process (GO:0042402)2.66974441
128L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.65454803
129drug catabolic process (GO:0042737)2.65342739
130microtubule-based movement (GO:0007018)2.64859291
131phosphatidylethanolamine metabolic process (GO:0046337)2.64116481
132meiotic cell cycle (GO:0051321)2.62806306
133microtubule bundle formation (GO:0001578)2.62534837
134microtubule polymerization or depolymerization (GO:0031109)2.62160444
135tryptophan metabolic process (GO:0006568)2.62122438
136negative regulation of telomere maintenance (GO:0032205)2.61020361
137embryonic camera-type eye development (GO:0031076)2.60635915
138G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.60247336
139synaptic transmission, cholinergic (GO:0007271)2.56796783
140single strand break repair (GO:0000012)2.56183346
141carnitine transport (GO:0015879)2.55678428
142amino-acid betaine transport (GO:0015838)2.55678428
143face development (GO:0060324)2.54835093
144meiosis I (GO:0007127)2.53903316
145carnitine transmembrane transport (GO:1902603)2.53872509
146genitalia morphogenesis (GO:0035112)2.53205090
147positive regulation of meiosis (GO:0045836)2.53170856
148DNA packaging (GO:0006323)2.52711845
149cardiac myofibril assembly (GO:0055003)2.51163918
150centriole assembly (GO:0098534)2.50685121
151positive regulation of chemokine secretion (GO:0090197)2.50311571
152positive regulation of defense response to virus by host (GO:0002230)2.49820822
153positive regulation of cell fate commitment (GO:0010455)2.47990795
154photoreceptor cell development (GO:0042461)2.47669279
155protein localization to Golgi apparatus (GO:0034067)2.47559019
156positive regulation of cellular response to oxidative stress (GO:1900409)2.47378149
157positive regulation of response to oxidative stress (GO:1902884)2.47378149
158smoothened signaling pathway (GO:0007224)2.46903642
159embryonic forelimb morphogenesis (GO:0035115)2.46701207
160kidney morphogenesis (GO:0060993)2.45368282
161determination of left/right symmetry (GO:0007368)2.44967339
162regulation of action potential (GO:0098900)2.44280396
163pyrimidine nucleobase catabolic process (GO:0006208)2.43798436
164sperm motility (GO:0030317)10.0705992

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.96880591
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.80550106
3EZH2_22144423_ChIP-Seq_EOC_Human3.74171089
4STAT6_21828071_ChIP-Seq_BEAS2B_Human2.62084271
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.54458141
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.48216964
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.42233932
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.28959768
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.18467780
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.16668677
11IGF1R_20145208_ChIP-Seq_DFB_Human2.16652616
12PCGF2_27294783_Chip-Seq_ESCs_Mouse2.12843735
13SMAD_19615063_ChIP-ChIP_OVARY_Human2.02921707
14VDR_22108803_ChIP-Seq_LS180_Human1.89153637
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.82428831
16TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81918738
17PCGF2_27294783_Chip-Seq_NPCs_Mouse1.73367083
18SALL1_21062744_ChIP-ChIP_HESCs_Human1.71990453
19EP300_21415370_ChIP-Seq_HL-1_Mouse1.67402030
20SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.62023072
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.60569383
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59991980
23PIAS1_25552417_ChIP-Seq_VCAP_Human1.59547805
24KDM2B_26808549_Chip-Seq_REH_Human1.56813849
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56501557
26EWS_26573619_Chip-Seq_HEK293_Human1.55251771
27AR_25329375_ChIP-Seq_VCAP_Human1.54724444
28BCAT_22108803_ChIP-Seq_LS180_Human1.54041933
29EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.53650729
30TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.53287356
31GBX2_23144817_ChIP-Seq_PC3_Human1.53018064
32NFE2_27457419_Chip-Seq_LIVER_Mouse1.50815749
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.50446694
34POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.48824987
35TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48824987
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.48160181
37AR_21572438_ChIP-Seq_LNCaP_Human1.47935441
38SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47675865
39NR3C1_21868756_ChIP-Seq_MCF10A_Human1.46463602
40TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46298054
41MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.46194334
42WDR5_24793694_ChIP-Seq_LNCAP_Human1.44303320
43TP53_22573176_ChIP-Seq_HFKS_Human1.43484209
44NANOG_18555785_Chip-Seq_ESCs_Mouse1.42412432
45TAF15_26573619_Chip-Seq_HEK293_Human1.41979291
46RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41946728
47SOX2_19829295_ChIP-Seq_ESCs_Human1.41013787
48NANOG_19829295_ChIP-Seq_ESCs_Human1.41013787
49KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.38003679
50TCF4_22108803_ChIP-Seq_LS180_Human1.35400201
51MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.34081045
52GATA3_21878914_ChIP-Seq_MCF-7_Human1.33522508
53RUNX2_22187159_ChIP-Seq_PCA_Human1.31682649
54RNF2_27304074_Chip-Seq_NSC_Mouse1.31201567
55PRDM14_20953172_ChIP-Seq_ESCs_Human1.30777235
56FOXA1_25329375_ChIP-Seq_VCAP_Human1.30258138
57FOXA1_27270436_Chip-Seq_PROSTATE_Human1.30258138
58SMAD4_21741376_ChIP-Seq_EPCs_Human1.29846818
59FUS_26573619_Chip-Seq_HEK293_Human1.28970154
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27836608
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.27067255
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25816528
63CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.25724170
64STAT1_17558387_ChIP-Seq_HELA_Human1.25372552
65EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.24700116
66TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.24015613
67BMI1_23680149_ChIP-Seq_NPCS_Mouse1.22915439
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.22269323
69FOXA1_21572438_ChIP-Seq_LNCaP_Human1.22204586
70DROSHA_22980978_ChIP-Seq_HELA_Human1.22048066
71ZNF274_21170338_ChIP-Seq_K562_Hela1.21012914
72TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19991632
73TAL1_26923725_Chip-Seq_HPCs_Mouse1.19918104
74GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19578079
75P53_22387025_ChIP-Seq_ESCs_Mouse1.19519231
76AUTS2_25519132_ChIP-Seq_293T-REX_Human1.19252520
77SMAD4_21799915_ChIP-Seq_A2780_Human1.19221623
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.18406990
79NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18250888
80TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17697455
81CMYC_18555785_Chip-Seq_ESCs_Mouse1.15517837
82ETV2_25802403_ChIP-Seq_MESCs_Mouse1.15281197
83TBL1_22424771_ChIP-Seq_293T_Human1.15067027
84PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14577559
85CRX_20693478_ChIP-Seq_RETINA_Mouse1.14352675
86ELK4_26923725_Chip-Seq_MESODERM_Mouse1.14314395
87GF1_26923725_Chip-Seq_HPCs_Mouse1.13886029
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13742082
89IRF1_19129219_ChIP-ChIP_H3396_Human1.13528134
90SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.13456541
91SMAD3_21741376_ChIP-Seq_EPCs_Human1.13061401
92CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11821721
93HOXB7_26014856_ChIP-Seq_BT474_Human1.11574254
94OCT4_18555785_Chip-Seq_ESCs_Mouse1.10173740
95STAT3_23295773_ChIP-Seq_U87_Human1.09745815
96CDX2_22108803_ChIP-Seq_LS180_Human1.09537508
97TCF4_23295773_ChIP-Seq_U87_Human1.09511506
98NCOR_22424771_ChIP-Seq_293T_Human1.09304673
99E2F1_18555785_Chip-Seq_ESCs_Mouse1.09159663
100RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09150186
101CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08821741
102AR_20517297_ChIP-Seq_VCAP_Human1.07956500
103IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.07953411
104CBP_20019798_ChIP-Seq_JUKART_Human1.07953411
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07824386
106OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07602585
107RBPJ_21746931_ChIP-Seq_IB4_Human1.07281460
108SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06662019
109FLI1_21867929_ChIP-Seq_TH2_Mouse1.05787017
110CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.05624781
111ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05555641
112ETV1_20927104_ChIP-Seq_GIST48_Human1.05337032
113PHF8_20622853_ChIP-Seq_HELA_Human1.04954024
114P300_19829295_ChIP-Seq_ESCs_Human1.04385721
115ARNT_22903824_ChIP-Seq_MCF-7_Human1.04049053
116ERA_21632823_ChIP-Seq_H3396_Human1.03793843
117P300_18555785_Chip-Seq_ESCs_Mouse1.03586193
118NOTCH1_21737748_ChIP-Seq_TLL_Human1.03558858
119SUZ12_27294783_Chip-Seq_ESCs_Mouse1.03484140
120KAP1_22055183_ChIP-Seq_ESCs_Mouse1.03281151
121NFYB_21822215_ChIP-Seq_K562_Human1.03029867
122GATA1_26923725_Chip-Seq_HPCs_Mouse1.02752189
123NANOG_20526341_ChIP-Seq_ESCs_Human1.02415567
124PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.02182565
125ESRRB_18555785_Chip-Seq_ESCs_Mouse1.01719680
126EGR1_23403033_ChIP-Seq_LIVER_Mouse1.01415750
127TAF2_19829295_ChIP-Seq_ESCs_Human1.01367923
128PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.01279529
129SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.00801581
130NFYA_21822215_ChIP-Seq_K562_Human1.00632942
131CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.00143337
132FOXH1_21741376_ChIP-Seq_EPCs_Human1.00117841
133ER_23166858_ChIP-Seq_MCF-7_Human0.99891801
134PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99520278
135OCT4_21477851_ChIP-Seq_ESCs_Mouse0.99282584
136CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99032628
137PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98530817
138SOX2_18555785_Chip-Seq_ESCs_Mouse0.98351950
139NMYC_18555785_Chip-Seq_ESCs_Mouse0.98301259
140EZH2_27294783_Chip-Seq_ESCs_Mouse0.97475126
141STAT3_18555785_Chip-Seq_ESCs_Mouse0.96909185
142CTBP1_25329375_ChIP-Seq_LNCAP_Human0.96867189
143GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.96511100
144CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96415192
145AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95862364
146RNF2_27304074_Chip-Seq_ESCs_Mouse0.95791473
147EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.93655192
148PU1_27457419_Chip-Seq_LIVER_Mouse0.93522165
149REST_21632747_ChIP-Seq_MESCs_Mouse0.92911589
150GF1B_26923725_Chip-Seq_HPCs_Mouse0.92266608
151FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92222482
152SMAD3_21741376_ChIP-Seq_ESCs_Human0.91908121
153SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90829791

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive4.11246593
2MP0001929_abnormal_gametogenesis3.75521407
3MP0005670_abnormal_white_adipose3.18954201
4MP0004233_abnormal_muscle_weight2.85792861
5MP0008877_abnormal_DNA_methylation2.71450257
6MP0003195_calcinosis2.67790869
7MP0002282_abnormal_trachea_morphology2.66040955
8MP0005623_abnormal_meninges_morphology2.65446296
9MP0005551_abnormal_eye_electrophysiolog2.64422772
10MP0002653_abnormal_ependyma_morphology2.54306987
11MP0002210_abnormal_sex_determination2.41660141
12MP0003646_muscle_fatigue2.33294859
13MP0002161_abnormal_fertility/fecundity2.30857692
14MP0004036_abnormal_muscle_relaxation2.30679613
15MP0004484_altered_response_of2.29230216
16MP0003011_delayed_dark_adaptation2.17549080
17MP0005253_abnormal_eye_physiology2.14958805
18MP0004133_heterotaxia2.11389529
19MP0005410_abnormal_fertilization11.1998121
20MP0009046_muscle_twitch1.99302429
21MP0002249_abnormal_larynx_morphology1.96141812
22MP0008875_abnormal_xenobiotic_pharmacok1.95286281
23MP0004130_abnormal_muscle_cell1.91132611
24MP0000372_irregular_coat_pigmentation1.86280186
25MP0004084_abnormal_cardiac_muscle1.85709975
26MP0001145_abnormal_male_reproductive1.82977009
27MP0008872_abnormal_physiological_respon1.80612916
28MP0006072_abnormal_retinal_apoptosis1.79211018
29MP0004043_abnormal_pH_regulation1.78406926
30MP0000751_myopathy1.76279317
31MP0003136_yellow_coat_color1.75161509
32MP0000653_abnormal_sex_gland1.73106511
33MP0003283_abnormal_digestive_organ1.70493518
34MP0009745_abnormal_behavioral_response1.65140828
35MP0004142_abnormal_muscle_tone1.64675498
36MP0004185_abnormal_adipocyte_glucose1.64557817
37MP0003942_abnormal_urinary_system1.62891839
38MP0003950_abnormal_plasma_membrane1.62671162
39MP0001486_abnormal_startle_reflex1.57546153
40MP0002736_abnormal_nociception_after1.56308662
41MP0005666_abnormal_adipose_tissue1.55483367
42MP0001485_abnormal_pinna_reflex1.55356315
43MP0003122_maternal_imprinting1.55352130
44MP0005377_hearing/vestibular/ear_phenot1.55340796
45MP0003878_abnormal_ear_physiology1.55340796
46MP0004215_abnormal_myocardial_fiber1.55310717
47MP0000569_abnormal_digit_pigmentation1.54717271
48MP0000678_abnormal_parathyroid_gland1.53719566
49MP0001873_stomach_inflammation1.52968815
50MP0001501_abnormal_sleep_pattern1.50940633
51MP0002009_preneoplasia1.50166697
52MP0002102_abnormal_ear_morphology1.49803014
53MP0003787_abnormal_imprinting1.48560419
54MP0010630_abnormal_cardiac_muscle1.46795687
55MP0000631_abnormal_neuroendocrine_gland1.43713076
56MP0002272_abnormal_nervous_system1.39286096
57MP0002876_abnormal_thyroid_physiology1.36710301
58MP0005620_abnormal_muscle_contractility1.33985935
59MP0002938_white_spotting1.30386988
60MP0001984_abnormal_olfaction1.29255985
61MP0003121_genomic_imprinting1.27696184
62MP0003718_maternal_effect1.26330583
63MP0003880_abnormal_central_pattern1.25795994
64MP0002733_abnormal_thermal_nociception1.24787022
65MP0002572_abnormal_emotion/affect_behav1.24053965
66MP0000427_abnormal_hair_cycle1.22151348
67MP0001970_abnormal_pain_threshold1.21759349
68MP0005647_abnormal_sex_gland1.21675748
69MP0000767_abnormal_smooth_muscle1.20810311
70MP0005646_abnormal_pituitary_gland1.20000864
71MP0004885_abnormal_endolymph1.17947244
72MP0001905_abnormal_dopamine_level1.17177848
73MP0004742_abnormal_vestibular_system1.16856835
74MP0003890_abnormal_embryonic-extraembry1.16299055
75MP0000383_abnormal_hair_follicle1.12872700
76MP0006292_abnormal_olfactory_placode1.12848042
77MP0005389_reproductive_system_phenotype1.12619234
78MP0002557_abnormal_social/conspecific_i1.11674743
79MP0001879_abnormal_lymphatic_vessel1.11654348
80MP0004087_abnormal_muscle_fiber1.11629485
81MP0008775_abnormal_heart_ventricle1.11187731
82MP0002269_muscular_atrophy1.11019381
83MP0002734_abnormal_mechanical_nocicepti1.10804013
84MP0002067_abnormal_sensory_capabilities1.08736020
85MP0003279_aneurysm1.08160567
86MP0001727_abnormal_embryo_implantation1.07885084
87MP0005171_absent_coat_pigmentation1.07678517
88MP0001919_abnormal_reproductive_system1.05749873
89MP0002160_abnormal_reproductive_system1.04985050
90MP0004145_abnormal_muscle_electrophysio1.02461857
91MP0005195_abnormal_posterior_eye1.01188956
92MP0002064_seizures1.00633958
93MP0002909_abnormal_adrenal_gland1.00389568
94MP0006138_congestive_heart_failure0.99896445
95MP0005085_abnormal_gallbladder_physiolo0.99071363
96MP0002972_abnormal_cardiac_muscle0.98785253
97MP0000026_abnormal_inner_ear0.98739675
98MP0004085_abnormal_heartbeat0.98531826
99MP0005423_abnormal_somatic_nervous0.98157988
100MP0004272_abnormal_basement_membrane0.97610669
101MP0004924_abnormal_behavior0.97236452
102MP0005386_behavior/neurological_phenoty0.97236452
103MP0003045_fibrosis0.96548766
104MP0002234_abnormal_pharynx_morphology0.96244954
105MP0005451_abnormal_body_composition0.94341400
106MP0002127_abnormal_cardiovascular_syste0.93232057
107MP0001529_abnormal_vocalization0.92713908
108MP0002229_neurodegeneration0.91910814
109MP0002752_abnormal_somatic_nervous0.91008110
110MP0010386_abnormal_urinary_bladder0.90502258
111MP0003635_abnormal_synaptic_transmissio0.90174129
112MP0002837_dystrophic_cardiac_calcinosis0.89170970
113MP0005379_endocrine/exocrine_gland_phen0.89085000
114MP0005084_abnormal_gallbladder_morpholo0.88456419
115MP0002751_abnormal_autonomic_nervous0.88098697
116MP0005167_abnormal_blood-brain_barrier0.86891414
117MP0008789_abnormal_olfactory_epithelium0.86423933
118MP0000013_abnormal_adipose_tissue0.86278619
119MP0005645_abnormal_hypothalamus_physiol0.85410554
120MP0001544_abnormal_cardiovascular_syste0.84006494
121MP0005385_cardiovascular_system_phenoty0.84006494
122MP0001188_hyperpigmentation0.82678489
123MP0010329_abnormal_lipoprotein_level0.82422354
124MP0001963_abnormal_hearing_physiology0.82027909
125MP0005330_cardiomyopathy0.81656209
126MP0001764_abnormal_homeostasis0.81053186
127MP0003941_abnormal_skin_development0.80726482
128MP0005375_adipose_tissue_phenotype0.79711513
129MP0005503_abnormal_tendon_morphology0.79588119
130MP0002063_abnormal_learning/memory/cond0.79286196
131MP0001502_abnormal_circadian_rhythm0.78975433
132MP0002184_abnormal_innervation0.77873555
133MP0001324_abnormal_eye_pigmentation0.77472937
134MP0003115_abnormal_respiratory_system0.77275992
135MP0009115_abnormal_fat_cell0.77183208
136MP0005083_abnormal_biliary_tract0.76092991
137MP0000778_abnormal_nervous_system0.75990841
138MP0005165_increased_susceptibility_to0.75361445
139MP0002928_abnormal_bile_duct0.72702704
140MP0001765_abnormal_ion_homeostasis0.72240703
141MP0008961_abnormal_basal_metabolism0.68343798
142MP0003123_paternal_imprinting0.65567757
143MP0009384_cardiac_valve_regurgitation0.64926221
144MP0001958_emphysema0.64487518
145MP0003385_abnormal_body_wall0.64297140
146MP0003948_abnormal_gas_homeostasis0.61466378
147MP0000266_abnormal_heart_morphology0.60917062
148MP0005275_abnormal_skin_tensile0.60743045
149MP0002638_abnormal_pupillary_reflex0.60228118
150MP0002332_abnormal_exercise_endurance0.59746805
151MP0000534_abnormal_ureter_morphology0.58319583
152MP0005595_abnormal_vascular_smooth0.57939411
153MP0006054_spinal_hemorrhage0.57902374
154MP0000759_abnormal_skeletal_muscle0.57334073
155MP0003699_abnormal_female_reproductive0.56689985
156MP0002735_abnormal_chemical_nociception0.56379212
157MP0002106_abnormal_muscle_physiology0.56047262
158MP0010368_abnormal_lymphatic_system0.55881327
159MP0001661_extended_life_span0.54808503
160MP0000343_altered_response_to0.54219953
161MP0001119_abnormal_female_reproductive0.54184595
162MP0006276_abnormal_autonomic_nervous0.53708659
163MP0000230_abnormal_systemic_arterial0.53077213
164MP0008995_early_reproductive_senescence0.53073756
165MP0003221_abnormal_cardiomyocyte_apopto0.51807595
166MP0001614_abnormal_blood_vessel0.50970751
167MP0009250_abnormal_appendicular_skeleto0.50814850
168MP0001986_abnormal_taste_sensitivity0.50636746
169MP0003943_abnormal_hepatobiliary_system0.50420688
170MP0001968_abnormal_touch/_nociception0.50067197
171MP0001851_eye_inflammation0.49100042

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.90157521
2Absent/shortened dynein arms (HP:0200106)9.73886064
3Dynein arm defect of respiratory motile cilia (HP:0012255)9.73886064
4Abnormal respiratory motile cilium physiology (HP:0012261)8.15601071
5Abnormal ciliary motility (HP:0012262)7.16901854
6Abnormal respiratory epithelium morphology (HP:0012253)6.98893130
7Abnormal respiratory motile cilium morphology (HP:0005938)6.98893130
8Rhinitis (HP:0012384)5.91372385
9Infertility (HP:0000789)5.88016814
10Nasal polyposis (HP:0100582)5.59328472
11Chronic bronchitis (HP:0004469)4.98899602
12Male infertility (HP:0003251)4.92247220
13Abnormality of the nasal mucosa (HP:0000433)4.68217327
14Pancreatic fibrosis (HP:0100732)4.66785239
15Pancreatic cysts (HP:0001737)4.58222126
16Tubulointerstitial nephritis (HP:0001970)4.08388131
17Bronchiectasis (HP:0002110)3.95847068
18Nephronophthisis (HP:0000090)3.75752947
19Exercise-induced myalgia (HP:0003738)3.65457618
20Recurrent sinusitis (HP:0011108)3.40779747
21Bronchitis (HP:0012387)3.36885646
22Polydipsia (HP:0001959)3.24517857
23Abnormal drinking behavior (HP:0030082)3.24517857
24Congenital stationary night blindness (HP:0007642)3.20884244
25Abnormality of the renal cortex (HP:0011035)3.18893076
26Type II lissencephaly (HP:0007260)3.16430236
27Autoimmune thrombocytopenia (HP:0001973)3.11269703
28Abnormality of the renal medulla (HP:0100957)2.94572084
29Easy fatigability (HP:0003388)2.91310139
30Molar tooth sign on MRI (HP:0002419)2.88520795
31Abnormality of midbrain morphology (HP:0002418)2.88520795
32Abnormal rod and cone electroretinograms (HP:0008323)2.84698971
33Attenuation of retinal blood vessels (HP:0007843)2.83010460
34Abnormality of the neuromuscular junction (HP:0003398)2.71581195
35Fatigable weakness (HP:0003473)2.71581195
36Short nail (HP:0001799)2.62182275
37Anterior segment dysgenesis (HP:0007700)2.59705937
38Anencephaly (HP:0002323)2.58372659
39Tubulointerstitial abnormality (HP:0001969)2.57843481
40Abnormality of dentin (HP:0010299)2.57418913
41Birth length less than 3rd percentile (HP:0003561)2.57194797
42Recurrent otitis media (HP:0000403)2.56463344
43Sclerocornea (HP:0000647)2.54260596
44Aplasia/Hypoplasia of the tongue (HP:0010295)2.52003197
45Cerebellar dysplasia (HP:0007033)2.51150066
46Bony spicule pigmentary retinopathy (HP:0007737)2.46272824
47Polyuria (HP:0000103)2.46217684
48Lower limb amyotrophy (HP:0007210)2.43242311
49Decreased muscle mass (HP:0003199)2.41586298
50Autoimmune hemolytic anemia (HP:0001890)2.39731747
51Hyporeflexia of lower limbs (HP:0002600)2.39609376
52Absent rod-and cone-mediated responses on ERG (HP:0007688)2.38461074
53Bundle branch block (HP:0011710)2.37825252
54Gait imbalance (HP:0002141)2.36482917
55Congenital primary aphakia (HP:0007707)2.35624003
56Progressive cerebellar ataxia (HP:0002073)2.32270765
57Distal lower limb amyotrophy (HP:0008944)2.31569617
58Recurrent bronchitis (HP:0002837)2.28876342
59Distal lower limb muscle weakness (HP:0009053)2.24969570
60Hyperventilation (HP:0002883)2.24104083
61Alveolar cell carcinoma (HP:0006519)2.22625869
62Genital tract atresia (HP:0001827)2.22375918
63Toxemia of pregnancy (HP:0100603)2.22353893
64Nephrogenic diabetes insipidus (HP:0009806)2.21607357
65Bulbar palsy (HP:0001283)2.19472654
66Increased corneal curvature (HP:0100692)2.17644416
67Keratoconus (HP:0000563)2.17644416
68Abnormal biliary tract physiology (HP:0012439)2.16535947
69Bile duct proliferation (HP:0001408)2.16535947
70Broad distal phalanx of finger (HP:0009836)2.16018961
71Abnormality of macular pigmentation (HP:0008002)2.14997388
72Genetic anticipation (HP:0003743)2.14706545
73Nonprogressive disorder (HP:0003680)2.14603320
74Gaze-evoked nystagmus (HP:0000640)2.13077783
75Weak cry (HP:0001612)2.11207244
76Prostate neoplasm (HP:0100787)2.10051314
77Abnormal urine output (HP:0012590)2.07969411
78Vaginal atresia (HP:0000148)2.07839709
79Large for gestational age (HP:0001520)2.06370390
80Abolished electroretinogram (ERG) (HP:0000550)2.04938263
81Asymmetric septal hypertrophy (HP:0001670)2.03922602
82Exercise-induced muscle cramps (HP:0003710)2.03366245
83Type 2 muscle fiber atrophy (HP:0003554)2.00930444
84Neoplasm of the tracheobronchial system (HP:0100552)1.99635781
85Atrial fibrillation (HP:0005110)1.99374127
86Aplasia/Hypoplasia of the tibia (HP:0005772)1.99243861
87Furrowed tongue (HP:0000221)1.97772059
88Progressive sensorineural hearing impairment (HP:0000408)1.93790457
89Postaxial foot polydactyly (HP:0001830)1.93193000
90Decreased central vision (HP:0007663)1.92741339
91Postaxial hand polydactyly (HP:0001162)1.92381999
92Cystic liver disease (HP:0006706)1.92377360
93Congenital hepatic fibrosis (HP:0002612)1.91527254
94Abnormality of alanine metabolism (HP:0010916)1.91360569
95Hyperalaninemia (HP:0003348)1.91360569
96Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.91360569
97Chronic sinusitis (HP:0011109)1.91296934
98Abnormality of molar (HP:0011077)1.90631270
99Abnormality of molar morphology (HP:0011070)1.90631270
100Preaxial hand polydactyly (HP:0001177)1.89922350
101Inability to walk (HP:0002540)1.89344789
102Tubular atrophy (HP:0000092)1.88670092
103Concave nail (HP:0001598)1.87550472
104Stage 5 chronic kidney disease (HP:0003774)1.87170030
105Abnormality of the dental root (HP:0006486)1.87103086
106Taurodontia (HP:0000679)1.87103086
107Abnormality of permanent molar morphology (HP:0011071)1.87103086
108Abnormal spermatogenesis (HP:0008669)1.86958108
109Sudden death (HP:0001699)1.86592331
110Retinal dysplasia (HP:0007973)1.86081671
111Abnormality of renal excretion (HP:0011036)1.84178605
112Insulin-resistant diabetes mellitus (HP:0000831)1.83349637
113Disinhibition (HP:0000734)1.83168195
114Abnormality of skeletal muscle fiber size (HP:0012084)1.83155401
115Ventricular tachycardia (HP:0004756)1.82576145
116Pendular nystagmus (HP:0012043)1.81635048
117Lissencephaly (HP:0001339)1.81512335
118Renal cortical cysts (HP:0000803)1.81315063
119Enlarged epiphyses (HP:0010580)1.80606912
120Decreased circulating renin level (HP:0003351)1.79490933
121Progressive hearing impairment (HP:0001730)1.78462543
122Supernumerary spleens (HP:0009799)1.77616816
123Aplasia/Hypoplasia of the spleen (HP:0010451)1.76702037
124Primary atrial arrhythmia (HP:0001692)1.76122441
125Congenital sensorineural hearing impairment (HP:0008527)1.76007437
126Mutism (HP:0002300)1.75666556
127Constricted visual fields (HP:0001133)1.75547584
128Facial diplegia (HP:0001349)1.75199828
129Agitation (HP:0000713)1.74711883
130True hermaphroditism (HP:0010459)1.74566733
131Fibular hypoplasia (HP:0003038)1.72047714
132Abnormality of the dental pulp (HP:0006479)1.71683539
133Pulmonary artery stenosis (HP:0004415)1.69047725
134Colitis (HP:0002583)1.67683598
135Polyphagia (HP:0002591)1.66750128
136Abnormal delayed hypersensitivity skin test (HP:0002963)1.66439248
137Syncope (HP:0001279)1.66344768
138Progressive inability to walk (HP:0002505)1.65866204
139Generalized muscle weakness (HP:0003324)1.65848988
140Epileptic encephalopathy (HP:0200134)1.65709830
141Abnormality of lateral ventricle (HP:0030047)1.65326717
142Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.64260586
143Chronic hepatic failure (HP:0100626)1.63960317
144Poor coordination (HP:0002370)1.63103565
145Gowers sign (HP:0003391)1.63033188
146Supraventricular tachycardia (HP:0004755)1.62303679
147Stomach cancer (HP:0012126)1.61733993
148Absent speech (HP:0001344)1.61295321
149Broad-based gait (HP:0002136)1.60746259
150Flattened epiphyses (HP:0003071)1.60456839
151Optic nerve hypoplasia (HP:0000609)1.59683364
152Asplenia (HP:0001746)1.59667012
153Supraventricular arrhythmia (HP:0005115)1.58824210
154Prolonged QT interval (HP:0001657)1.54583944
155Medial flaring of the eyebrow (HP:0010747)1.52879153
156Muscle fiber atrophy (HP:0100295)1.49947829
157Widely spaced teeth (HP:0000687)1.48857823
158Heart block (HP:0012722)1.46232061
159Gonadotropin excess (HP:0000837)1.45430855
160Hypoplasia of the iris (HP:0007676)1.45165337
161Short humerus (HP:0005792)1.45018023
162Increased variability in muscle fiber diameter (HP:0003557)1.44411446
163Oculomotor apraxia (HP:0000657)1.42606214
164Increased connective tissue (HP:0009025)1.40205977
165Male pseudohermaphroditism (HP:0000037)1.40054612
166Calf muscle hypertrophy (HP:0008981)1.39864729
167Renal duplication (HP:0000075)1.39748028
168Occipital encephalocele (HP:0002085)1.39623685

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK36.49181509
2PDK46.49181509
3BMPR25.48589321
4TLK14.75029810
5DMPK3.99443709
6PDK23.99253795
7MAP4K23.48611987
8PRKD33.30721301
9INSRR3.01898076
10TESK12.99286794
11ADRBK22.60501066
12ICK2.55897475
13BMPR1B2.52625791
14MAPK152.37107777
15TAOK22.24723251
16PTK2B2.11195515
17ZAK2.04593707
18PLK42.00708311
19WNK31.88990410
20OXSR11.86839717
21CAMKK21.72452950
22LATS21.72337531
23CAMK1D1.61941217
24MAP3K51.58002070
25RIPK41.42349630
26STK391.40191407
27STK381.38877076
28WNK41.36742427
29MYLK1.32147364
30CASK1.24546327
31MAP3K41.21057021
32CDK191.19438115
33DAPK21.10535079
34MUSK1.10500443
35ACVR1B1.07220073
36EEF2K1.04171071
37PDK11.03167108
38WNK11.01727877
39ADRBK11.00820269
40TAOK31.00549184
41IRAK21.00521793
42FRK0.98409406
43GRK10.96945010
44TXK0.96163190
45MARK20.96035991
46LMTK20.94149404
47TNIK0.93888682
48NTRK30.93417779
49PRKD20.93292961
50STK38L0.92853266
51TRIM280.92508836
52PINK10.90263765
53PNCK0.89163848
54IRAK10.85168742
55BRSK20.84097081
56EPHB20.84028359
57MST40.83243168
58PRKCH0.82946465
59PIK3CG0.82543489
60MARK10.82220718
61MAP2K60.82066527
62TTN0.81188205
63GRK70.81051210
64TRIB30.80571536
65CAMK1G0.79418060
66RIPK10.77345799
67MKNK20.76453447
68KIT0.75767787
69STK30.74744298
70PRKCE0.74322347
71TAOK10.73374353
72GSK3A0.72048454
73NUAK10.71065586
74PRKAA10.70647872
75TRPM70.69395563
76FGFR20.69031292
77ERBB30.66995462
78MAPKAPK50.66365586
79ITK0.65195746
80NME10.63356405
81AKT30.62900479
82PIK3CA0.61751696
83LATS10.61424745
84PLK20.59281906
85SGK20.58615169
86EPHA40.57142451
87CDK90.55442030
88PRKAA20.52657533
89MARK30.51768772
90TYRO30.51696491
91NLK0.50965210
92DYRK20.49634355
93PDPK10.48763175
94TGFBR10.48016204
95ROCK10.47943796
96CSNK1G20.47170535
97FER0.46518795
98VRK10.45830948
99RET0.45231373
100NTRK20.45081708
101CDC42BPA0.44714498
102CAMK40.44239714
103NEK20.43955813
104EIF2AK30.43450680
105CAMK2A0.43378119
106PKN10.43356365
107MAP3K60.42923529
108PRKG10.42163162
109PRKACA0.40607826
110CSNK1G10.39702381
111MAP2K70.39538375
112SGK2230.39061092
113SGK4940.39061092
114MAPKAPK30.38921041
115NEK60.38818562
116PRKCZ0.37085217
117PRKD10.36769926
118TEC0.36258001
119PRKCQ0.35813750
120FGR0.35735267
121PDGFRB0.35579590
122STK100.35361428
123ALK0.35076254
124RPS6KA50.34211503
125MINK10.33936044
126CSNK1G30.33870185
127BCR0.33197868
128CCNB10.33018332
129IGF1R0.32490319
130PAK30.30838404
131SGK30.30381306
132TIE10.29881863
133MKNK10.29278860
134TNK20.29097124
135CAMKK10.29061317
136MTOR0.28660639
137PRKCA0.27614011
138DYRK30.27017477
139STK160.26669152
140MAP3K70.25648784
141OBSCN0.24590657
142PKN20.23461219
143PAK10.23443673
144STK110.23301675
145PHKG10.22151869
146PHKG20.22151869
147TGFBR20.21989468
148FGFR30.20259452
149PAK40.18429053
150MAPK70.18038494
151STK240.16884146
152PRKCG0.16171519
153PAK60.15575242
154MAPK80.15431141
155EIF2AK20.14446329
156PRKCB0.14181536
157DYRK1B0.14060445
158MAP3K130.13830595
159MAP4K10.13538944
160CAMK2D0.13538025
161MAPK130.13452036
162CAMK10.12052977
163IKBKB0.11958509
164MAPK110.11456776

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000613.28686076
2Phototransduction_Homo sapiens_hsa047443.25921419
3Caffeine metabolism_Homo sapiens_hsa002323.00437138
4Propanoate metabolism_Homo sapiens_hsa006402.97905832
5Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.73050205
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.45422210
7Nitrogen metabolism_Homo sapiens_hsa009102.39419473
8Butanoate metabolism_Homo sapiens_hsa006502.39137620
9Maturity onset diabetes of the young_Homo sapiens_hsa049502.29647121
10Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.17767232
11Ovarian steroidogenesis_Homo sapiens_hsa049132.10723189
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.09398802
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.09379917
14Glucagon signaling pathway_Homo sapiens_hsa049221.99446869
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.98308265
16Cardiac muscle contraction_Homo sapiens_hsa042601.94369294
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.85929818
18Dorso-ventral axis formation_Homo sapiens_hsa043201.79994907
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.74896751
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.73133035
21Linoleic acid metabolism_Homo sapiens_hsa005911.71224961
22Renin secretion_Homo sapiens_hsa049241.71133884
23Tryptophan metabolism_Homo sapiens_hsa003801.66170891
24Amphetamine addiction_Homo sapiens_hsa050311.65096260
25Olfactory transduction_Homo sapiens_hsa047401.61590205
26Chemical carcinogenesis_Homo sapiens_hsa052041.61574233
27ABC transporters_Homo sapiens_hsa020101.60416586
28Pyruvate metabolism_Homo sapiens_hsa006201.59957628
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53356979
30Selenocompound metabolism_Homo sapiens_hsa004501.49999125
31PPAR signaling pathway_Homo sapiens_hsa033201.49408218
32cGMP-PKG signaling pathway_Homo sapiens_hsa040221.46700257
33Oxidative phosphorylation_Homo sapiens_hsa001901.45893953
34Primary bile acid biosynthesis_Homo sapiens_hsa001201.43267418
35Dilated cardiomyopathy_Homo sapiens_hsa054141.41789870
36Oocyte meiosis_Homo sapiens_hsa041141.39731918
37Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.39622230
38Calcium signaling pathway_Homo sapiens_hsa040201.38690829
39Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.38010460
40Inositol phosphate metabolism_Homo sapiens_hsa005621.31942830
41Fatty acid degradation_Homo sapiens_hsa000711.31805878
42Protein export_Homo sapiens_hsa030601.31638821
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.31437351
44Fanconi anemia pathway_Homo sapiens_hsa034601.31271408
45Vascular smooth muscle contraction_Homo sapiens_hsa042701.30740214
46Carbohydrate digestion and absorption_Homo sapiens_hsa049731.26510544
47Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.25957836
48Phosphatidylinositol signaling system_Homo sapiens_hsa040701.23788469
49Circadian entrainment_Homo sapiens_hsa047131.22579219
50Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.16661298
51Insulin secretion_Homo sapiens_hsa049111.16201891
52Basal transcription factors_Homo sapiens_hsa030221.15286587
53RNA polymerase_Homo sapiens_hsa030201.14075645
54Peroxisome_Homo sapiens_hsa041461.10681836
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.09652545
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09516716
57Arachidonic acid metabolism_Homo sapiens_hsa005901.08872432
58Fatty acid metabolism_Homo sapiens_hsa012121.07879941
59Salivary secretion_Homo sapiens_hsa049701.06587973
60Glutamatergic synapse_Homo sapiens_hsa047241.06466174
61Homologous recombination_Homo sapiens_hsa034401.06422808
62Thyroid hormone signaling pathway_Homo sapiens_hsa049191.06142056
63Fat digestion and absorption_Homo sapiens_hsa049751.05721197
64Estrogen signaling pathway_Homo sapiens_hsa049151.04741384
65Retinol metabolism_Homo sapiens_hsa008301.04030469
66Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.99860134
67Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.98267658
68Oxytocin signaling pathway_Homo sapiens_hsa049210.96483237
69Glycerolipid metabolism_Homo sapiens_hsa005610.94375162
70cAMP signaling pathway_Homo sapiens_hsa040240.94158061
71Type I diabetes mellitus_Homo sapiens_hsa049400.93647207
72Regulation of autophagy_Homo sapiens_hsa041400.93625707
73B cell receptor signaling pathway_Homo sapiens_hsa046620.93316872
74Ether lipid metabolism_Homo sapiens_hsa005650.93284080
75Parkinsons disease_Homo sapiens_hsa050120.93097334
76Focal adhesion_Homo sapiens_hsa045100.92767587
77Allograft rejection_Homo sapiens_hsa053300.91676106
78GnRH signaling pathway_Homo sapiens_hsa049120.91458369
79Protein digestion and absorption_Homo sapiens_hsa049740.90572855
80Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.90464859
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.90232038
82Vitamin B6 metabolism_Homo sapiens_hsa007500.89624126
83Autoimmune thyroid disease_Homo sapiens_hsa053200.86431719
84Morphine addiction_Homo sapiens_hsa050320.86081855
85Histidine metabolism_Homo sapiens_hsa003400.86018499
86Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84595182
87Graft-versus-host disease_Homo sapiens_hsa053320.84363647
88ECM-receptor interaction_Homo sapiens_hsa045120.84348478
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.84228199
90Long-term potentiation_Homo sapiens_hsa047200.83861292
91T cell receptor signaling pathway_Homo sapiens_hsa046600.83657528
92Aldosterone synthesis and secretion_Homo sapiens_hsa049250.81422065
93Renin-angiotensin system_Homo sapiens_hsa046140.81174153
94Taste transduction_Homo sapiens_hsa047420.79127495
95Dopaminergic synapse_Homo sapiens_hsa047280.78048995
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.77338675
97Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.77284711
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.74981353
99Huntingtons disease_Homo sapiens_hsa050160.74846747
100Gastric acid secretion_Homo sapiens_hsa049710.74413916
101MAPK signaling pathway_Homo sapiens_hsa040100.74258413
102Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.71676269
103Hippo signaling pathway_Homo sapiens_hsa043900.71397952
104Intestinal immune network for IgA production_Homo sapiens_hsa046720.71117458
105Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.70940901
106beta-Alanine metabolism_Homo sapiens_hsa004100.69105044
107Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.67149383
108Serotonergic synapse_Homo sapiens_hsa047260.65917871
109AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65422074
110Wnt signaling pathway_Homo sapiens_hsa043100.65376065
111GABAergic synapse_Homo sapiens_hsa047270.64433449
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.64254688
113Mineral absorption_Homo sapiens_hsa049780.61775509
114VEGF signaling pathway_Homo sapiens_hsa043700.61313440
115Cholinergic synapse_Homo sapiens_hsa047250.60827014
116Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60400550
117Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59206809
118AMPK signaling pathway_Homo sapiens_hsa041520.59185919
119African trypanosomiasis_Homo sapiens_hsa051430.58927106
120Toxoplasmosis_Homo sapiens_hsa051450.58040055
121Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.57827926
122Osteoclast differentiation_Homo sapiens_hsa043800.57047536
123One carbon pool by folate_Homo sapiens_hsa006700.56590194
124Notch signaling pathway_Homo sapiens_hsa043300.56349003
125Metabolic pathways_Homo sapiens_hsa011000.53467072
126Vitamin digestion and absorption_Homo sapiens_hsa049770.52414572
127Insulin resistance_Homo sapiens_hsa049310.52388948
128Hedgehog signaling pathway_Homo sapiens_hsa043400.50964866
129Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.49136160
130Alzheimers disease_Homo sapiens_hsa050100.48896558
131Primary immunodeficiency_Homo sapiens_hsa053400.47740587
132Pancreatic cancer_Homo sapiens_hsa052120.47155838
133Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.47063394
134Purine metabolism_Homo sapiens_hsa002300.46955951
135Collecting duct acid secretion_Homo sapiens_hsa049660.45885021
136Nicotine addiction_Homo sapiens_hsa050330.45837097
137TNF signaling pathway_Homo sapiens_hsa046680.44090293
138Steroid biosynthesis_Homo sapiens_hsa001000.41816571
139Axon guidance_Homo sapiens_hsa043600.41776765
140Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.41085644
141TGF-beta signaling pathway_Homo sapiens_hsa043500.40492293
142Ras signaling pathway_Homo sapiens_hsa040140.39618563
143Type II diabetes mellitus_Homo sapiens_hsa049300.39003659
144Circadian rhythm_Homo sapiens_hsa047100.38254918
145Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.38016310
146Adherens junction_Homo sapiens_hsa045200.37884539
147Carbon metabolism_Homo sapiens_hsa012000.37487875
148PI3K-Akt signaling pathway_Homo sapiens_hsa041510.37387595
149Small cell lung cancer_Homo sapiens_hsa052220.37107736
150Amoebiasis_Homo sapiens_hsa051460.36978209
151Asthma_Homo sapiens_hsa053100.36940696
152Cyanoamino acid metabolism_Homo sapiens_hsa004600.36757570
153Pancreatic secretion_Homo sapiens_hsa049720.36487542
154Antigen processing and presentation_Homo sapiens_hsa046120.36457471
155Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.35664340
156RNA degradation_Homo sapiens_hsa030180.34422343
157Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34039364
158Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.29342992
159Tyrosine metabolism_Homo sapiens_hsa003500.28133421
160SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27787643
161Cocaine addiction_Homo sapiens_hsa050300.26422200

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »