LMO4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.36941643
2vocalization behavior (GO:0071625)5.34499472
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.15683173
4neuron cell-cell adhesion (GO:0007158)4.97199297
5protein localization to synapse (GO:0035418)4.88249589
6synaptic vesicle exocytosis (GO:0016079)4.85236725
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.76483411
8glutamate receptor signaling pathway (GO:0007215)4.70714801
9regulation of glutamate receptor signaling pathway (GO:1900449)4.52434257
10ionotropic glutamate receptor signaling pathway (GO:0035235)4.50962200
11sodium ion export (GO:0071436)4.50809686
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.49177977
13glutamate secretion (GO:0014047)4.34393241
14neuron recognition (GO:0008038)4.28255570
15gamma-aminobutyric acid transport (GO:0015812)4.21687906
16locomotory exploration behavior (GO:0035641)4.15615924
17regulation of long-term neuronal synaptic plasticity (GO:0048169)4.15597826
18presynaptic membrane assembly (GO:0097105)4.10563835
19cerebellar granule cell differentiation (GO:0021707)4.06473218
20gamma-aminobutyric acid signaling pathway (GO:0007214)4.05817878
21neuronal action potential propagation (GO:0019227)3.99751058
22G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.98960302
23regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.94996503
24exploration behavior (GO:0035640)3.94950009
25layer formation in cerebral cortex (GO:0021819)3.94741144
26response to histamine (GO:0034776)3.91674667
27dendritic spine morphogenesis (GO:0060997)3.89350214
28G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.85840597
29regulation of synaptic vesicle exocytosis (GO:2000300)3.85283868
30regulation of glutamate secretion (GO:0014048)3.84275573
31regulation of dendritic spine morphogenesis (GO:0061001)3.83628056
32L-amino acid import (GO:0043092)3.81229580
33postsynaptic membrane organization (GO:0001941)3.78745668
34positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.77742375
35axonal fasciculation (GO:0007413)3.75497629
36positive regulation of neurotransmitter secretion (GO:0001956)3.72393683
37negative regulation of synaptic transmission, GABAergic (GO:0032229)3.72228906
38synaptic vesicle maturation (GO:0016188)3.69494789
39regulation of excitatory postsynaptic membrane potential (GO:0060079)3.69062919
40neuron-neuron synaptic transmission (GO:0007270)3.68797465
41long-term synaptic potentiation (GO:0060291)3.68428836
42cell migration in hindbrain (GO:0021535)3.67795411
43cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.64935349
44regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.63525208
45positive regulation of synapse maturation (GO:0090129)3.60672892
46synaptic vesicle endocytosis (GO:0048488)3.59376819
47presynaptic membrane organization (GO:0097090)3.58930396
48negative regulation of amino acid transport (GO:0051956)3.58368742
49regulation of neuronal synaptic plasticity (GO:0048168)3.57386348
50synaptic transmission, glutamatergic (GO:0035249)3.56813258
51regulation of dendritic spine development (GO:0060998)3.55607148
52regulation of postsynaptic membrane potential (GO:0060078)3.53365810
53regulation of synaptic vesicle transport (GO:1902803)3.52979711
54axon ensheathment in central nervous system (GO:0032291)3.51160957
55central nervous system myelination (GO:0022010)3.51160957
56neuromuscular process controlling balance (GO:0050885)3.48180120
57amino acid import (GO:0043090)3.47287037
58synaptic vesicle docking involved in exocytosis (GO:0016081)3.47171156
59behavioral response to cocaine (GO:0048148)3.39304809
60negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.37740687
61negative regulation of cell killing (GO:0031342)3.37740687
62regulation of synaptic plasticity (GO:0048167)3.36792539
63cell communication by electrical coupling (GO:0010644)3.35813884
64regulation of neurotransmitter levels (GO:0001505)3.33435549
65behavioral defense response (GO:0002209)3.33372868
66behavioral fear response (GO:0001662)3.33372868
67potassium ion import (GO:0010107)3.30387500
68potassium ion homeostasis (GO:0055075)3.28843040
69cerebellar Purkinje cell layer development (GO:0021680)3.26345132
70fear response (GO:0042596)3.22186734
71cellular sodium ion homeostasis (GO:0006883)3.21676880
72long-term memory (GO:0007616)3.20382548
73positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.19207441
74regulation of synapse structural plasticity (GO:0051823)3.15887706
75regulation of synaptic transmission, glutamatergic (GO:0051966)3.13539274
76regulation of vesicle fusion (GO:0031338)3.12587085
77positive regulation of membrane potential (GO:0045838)3.11185110
78negative regulation of dendrite morphogenesis (GO:0050774)3.10853948
79positive regulation of dendritic spine morphogenesis (GO:0061003)3.10549629
80membrane depolarization during action potential (GO:0086010)3.07619581
81neuronal ion channel clustering (GO:0045161)3.07064101
82positive regulation of synapse assembly (GO:0051965)3.01914294
83regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.01912645
84proline transport (GO:0015824)3.00732818
85neurotransmitter secretion (GO:0007269)2.99830255
86auditory behavior (GO:0031223)2.99196101
87positive regulation of dendritic spine development (GO:0060999)2.98477259
88dendritic spine organization (GO:0097061)2.98263084
89positive regulation of neurotransmitter transport (GO:0051590)2.97502019
90activation of protein kinase A activity (GO:0034199)2.96395165
91neuromuscular synaptic transmission (GO:0007274)2.94518185
92positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.93636240
93central nervous system projection neuron axonogenesis (GO:0021952)2.93211628
94urinary tract smooth muscle contraction (GO:0014848)2.92806758
95synaptic transmission (GO:0007268)2.89368955
96cellular potassium ion homeostasis (GO:0030007)2.89356697
97transmission of nerve impulse (GO:0019226)2.88666541
98innervation (GO:0060384)2.88269284
99neuromuscular process (GO:0050905)2.87770594
100serotonin metabolic process (GO:0042428)2.87356465
101startle response (GO:0001964)2.86636531
102regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.86473610
103long term synaptic depression (GO:0060292)2.85951971
104regulation of neurotransmitter transport (GO:0051588)2.85451649
105neurotransmitter-gated ion channel clustering (GO:0072578)2.85121880
106positive regulation of cellular response to oxidative stress (GO:1900409)2.85084954
107positive regulation of response to oxidative stress (GO:1902884)2.85084954
108regulation of voltage-gated calcium channel activity (GO:1901385)2.84627381
109regulation of neurotransmitter secretion (GO:0046928)2.84055210
110adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.83662631
111synapse assembly (GO:0007416)2.81564001
112negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.80702018
113response to auditory stimulus (GO:0010996)2.80435812
114membrane depolarization (GO:0051899)2.80050646
115dendrite morphogenesis (GO:0048813)2.79092396
116learning (GO:0007612)2.77911624
117regulation of inositol phosphate biosynthetic process (GO:0010919)2.74025878
118neuron remodeling (GO:0016322)2.73107299
119mating behavior (GO:0007617)2.72321299
120regulation of synapse maturation (GO:0090128)2.71189213
121female mating behavior (GO:0060180)2.70739461
122establishment of synaptic vesicle localization (GO:0097480)2.68052841
123synaptic vesicle transport (GO:0048489)2.68052841
124regulation of synapse organization (GO:0050807)2.67067804
125social behavior (GO:0035176)2.66381754
126intraspecies interaction between organisms (GO:0051703)2.66381754
127righting reflex (GO:0060013)2.66118244
128regulation of synaptic transmission (GO:0050804)2.64747348
129cochlea development (GO:0090102)2.63902158
130regulation of synapse assembly (GO:0051963)2.62494182
131positive regulation of synaptic transmission (GO:0050806)2.61967786
132ephrin receptor signaling pathway (GO:0048013)2.59845781
133regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.59722489
134positive regulation of vesicle fusion (GO:0031340)2.58908393
135neurotransmitter transport (GO:0006836)2.57198555
136positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.56560072

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.70061014
2GBX2_23144817_ChIP-Seq_PC3_Human3.64497501
3* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.47540095
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.32711483
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.23847267
6SUZ12_18974828_ChIP-Seq_MESCs_Mouse3.03386508
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.94057540
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.94057540
9* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.87306914
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.86122361
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.83022651
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.77564506
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.65978570
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51559943
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.41912105
16* RNF2_27304074_Chip-Seq_ESCs_Mouse2.35918891
17* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.34445329
18IKZF1_21737484_ChIP-ChIP_HCT116_Human2.31470532
19AR_21572438_ChIP-Seq_LNCaP_Human2.30222329
20RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.28144534
21* EZH2_27294783_Chip-Seq_ESCs_Mouse2.27860291
22* TAF15_26573619_Chip-Seq_HEK293_Human2.19664203
23* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.10922825
24* REST_21632747_ChIP-Seq_MESCs_Mouse2.05273526
25* CTBP1_25329375_ChIP-Seq_LNCAP_Human2.03333759
26DROSHA_22980978_ChIP-Seq_HELA_Human1.94189567
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.91966315
28* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86272555
29SMAD_19615063_ChIP-ChIP_OVARY_Human1.80876307
30PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.78244956
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.72606512
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.71841144
33* P300_19829295_ChIP-Seq_ESCs_Human1.70681323
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.69512230
35RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.68448613
36SMAD4_21799915_ChIP-Seq_A2780_Human1.65698107
37VDR_22108803_ChIP-Seq_LS180_Human1.62601247
38ZFP281_18757296_ChIP-ChIP_E14_Mouse1.62143495
39* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60668554
40FUS_26573619_Chip-Seq_HEK293_Human1.60352257
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.59305604
42RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.56714647
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.51497627
44TP53_18474530_ChIP-ChIP_U2OS_Human1.50899591
45* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.49698092
46REST_18959480_ChIP-ChIP_MESCs_Mouse1.48710605
47TP53_16413492_ChIP-PET_HCT116_Human1.47606414
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.47124393
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.46636187
50NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.45894272
51GATA1_26923725_Chip-Seq_HPCs_Mouse1.45730368
52ZFP281_27345836_Chip-Seq_ESCs_Mouse1.44390196
53* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43609494
54* KDM2B_26808549_Chip-Seq_K562_Human1.43095706
55* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41518606
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40160250
57* RING1B_27294783_Chip-Seq_ESCs_Mouse1.39579484
58CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38188129
59ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.37912878
60MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.35815127
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35678511
62DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35577126
63AR_25329375_ChIP-Seq_VCAP_Human1.32375615
64SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31946164
65* CTCF_27219007_Chip-Seq_Bcells_Human1.31325507
66ZNF274_21170338_ChIP-Seq_K562_Hela1.30997544
67NR3C1_23031785_ChIP-Seq_PC12_Mouse1.28835624
68ZNF217_24962896_ChIP-Seq_MCF-7_Human1.27280036
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.26425270
70TRIM28_21343339_ChIP-Seq_HEK293_Human1.25721027
71SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.25036508
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.24424718
73* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22860026
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.22675735
75* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.22524049
76RNF2_27304074_Chip-Seq_NSC_Mouse1.21491800
77AHR_22903824_ChIP-Seq_MCF-7_Human1.21261196
78* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.21199031
79PRDM14_20953172_ChIP-Seq_ESCs_Human1.20349747
80* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20077230
81CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.18510789
82* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15713373
83TP53_20018659_ChIP-ChIP_R1E_Mouse1.14272149
84* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14261606
85OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.13853580
86* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.10271528
87RXR_22108803_ChIP-Seq_LS180_Human1.10224934
88TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09348220
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09348220
90P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09296103
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07061189
92* SOX2_21211035_ChIP-Seq_LN229_Gbm1.06629121
93* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05993830
94* BCAT_22108803_ChIP-Seq_LS180_Human1.05916002
95GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.04058057
96IGF1R_20145208_ChIP-Seq_DFB_Human1.03989044
97RUNX2_22187159_ChIP-Seq_PCA_Human1.03970844
98VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.03755237
99JUN_21703547_ChIP-Seq_K562_Human1.02929857
100* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.00516596
101ER_23166858_ChIP-Seq_MCF-7_Human1.00477986
102CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99030067
103NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98438394
104* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98255054
105WT1_19549856_ChIP-ChIP_CCG9911_Human0.97373958
106TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.96805953
107LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96686658
108YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96120533
109* NANOG_18555785_Chip-Seq_ESCs_Mouse0.95878256
110* AR_19668381_ChIP-Seq_PC3_Human0.94350955
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93469552
112* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92793097
113SMAD3_21741376_ChIP-Seq_ESCs_Human0.92319631
114TCF4_23295773_ChIP-Seq_U87_Human0.91961222
115EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91792880
116TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90806220
117RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89746900
118MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88976110
119NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.88939543
120NRF2_20460467_ChIP-Seq_MEFs_Mouse0.88939543
121* SOX9_26525672_Chip-Seq_HEART_Mouse0.88866119
122ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.88437646
123ESR2_21235772_ChIP-Seq_MCF-7_Human0.87242947
124ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.86785831
125SRY_22984422_ChIP-ChIP_TESTIS_Rat0.86751885
126* TET1_21490601_ChIP-Seq_MESCs_Mouse0.86394002
127PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.85304154
128* ISL1_27105846_Chip-Seq_CPCs_Mouse0.79936234
129* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.79148574
130SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.78571621
131PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.78553307
132* CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.78316381
133* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.77461690
134DPY_21335234_ChIP-Seq_ESCs_Mouse0.77155620
135* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.76454755

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern6.04813166
2MP0004859_abnormal_synaptic_plasticity6.03222246
3MP0003635_abnormal_synaptic_transmissio3.97310637
4MP0009745_abnormal_behavioral_response3.38759098
5MP0002063_abnormal_learning/memory/cond3.23861642
6MP0002064_seizures3.02316605
7MP0001968_abnormal_touch/_nociception3.01343014
8MP0004270_analgesia2.94832878
9MP0002572_abnormal_emotion/affect_behav2.74009646
10MP0001501_abnormal_sleep_pattern2.70531868
11MP0001440_abnormal_grooming_behavior2.53470021
12MP0002736_abnormal_nociception_after2.52046838
13MP0009046_muscle_twitch2.44553349
14MP0000566_synostosis2.31579308
15MP0001486_abnormal_startle_reflex2.27402858
16MP0002734_abnormal_mechanical_nocicepti2.20576912
17MP0002735_abnormal_chemical_nociception2.15553402
18MP0002272_abnormal_nervous_system2.14139262
19MP0000778_abnormal_nervous_system2.09337303
20MP0004858_abnormal_nervous_system1.98689056
21MP0003329_amyloid_beta_deposits1.89976979
22MP0002067_abnormal_sensory_capabilities1.83848761
23MP0002184_abnormal_innervation1.68467819
24MP0001970_abnormal_pain_threshold1.68170283
25MP0002733_abnormal_thermal_nociception1.67608028
26MP0006276_abnormal_autonomic_nervous1.63903742
27MP0005423_abnormal_somatic_nervous1.61918851
28MP0009379_abnormal_foot_pigmentation1.56307842
29MP0002557_abnormal_social/conspecific_i1.55091749
30MP0001188_hyperpigmentation1.54975369
31MP0004510_myositis1.50895087
32MP0009780_abnormal_chondrocyte_physiolo1.49183522
33MP0001346_abnormal_lacrimal_gland1.46343694
34MP0003879_abnormal_hair_cell1.44635241
35MP0003122_maternal_imprinting1.44586806
36MP0005386_behavior/neurological_phenoty1.44191234
37MP0004924_abnormal_behavior1.44191234
38MP0001905_abnormal_dopamine_level1.43278534
39MP0001984_abnormal_olfaction1.43131172
40MP0002837_dystrophic_cardiac_calcinosis1.42092909
41MP0010234_abnormal_vibrissa_follicle1.42091431
42MP0004811_abnormal_neuron_physiology1.41927146
43MP0002909_abnormal_adrenal_gland1.41447154
44MP0003303_peritoneal_inflammation1.38388430
45MP0005409_darkened_coat_color1.32746434
46MP0008569_lethality_at_weaning1.29359333
47MP0000955_abnormal_spinal_cord1.21021163
48MP0002882_abnormal_neuron_morphology1.20210347
49MP0000579_abnormal_nail_morphology1.20204930
50MP0001502_abnormal_circadian_rhythm1.17982002
51MP0010386_abnormal_urinary_bladder1.15294128
52MP0002066_abnormal_motor_capabilities/c1.14958729
53MP0004742_abnormal_vestibular_system1.13382457
54MP0003136_yellow_coat_color1.12287922
55MP0003787_abnormal_imprinting1.11290779
56MP0003690_abnormal_glial_cell1.10586273
57MP0008004_abnormal_stomach_pH1.07184280
58MP0003075_altered_response_to1.04469660
59MP0000631_abnormal_neuroendocrine_gland1.02331771
60MP0003633_abnormal_nervous_system1.02296765
61MP0000569_abnormal_digit_pigmentation1.00938185
62MP0005646_abnormal_pituitary_gland1.00443597
63MP0003123_paternal_imprinting0.99364985
64MP0001529_abnormal_vocalization0.97822258
65* MP0002152_abnormal_brain_morphology0.96681584
66MP0000604_amyloidosis0.96347075
67MP0000920_abnormal_myelination0.96087779
68MP0005623_abnormal_meninges_morphology0.95417107
69MP0008874_decreased_physiological_sensi0.94615198
70MP0005535_abnormal_body_temperature0.93112858
71MP0003283_abnormal_digestive_organ0.93014756
72MP0004133_heterotaxia0.92602836
73MP0001664_abnormal_digestion0.91957796
74MP0002102_abnormal_ear_morphology0.91791239
75MP0000751_myopathy0.90280351
76MP0004484_altered_response_of0.89699870
77MP0001299_abnormal_eye_distance/0.88322081
78MP0004145_abnormal_muscle_electrophysio0.86395208
79MP0003632_abnormal_nervous_system0.85792663
80MP0001963_abnormal_hearing_physiology0.84522412
81MP0005187_abnormal_penis_morphology0.83288391
82MP0005503_abnormal_tendon_morphology0.82531522
83MP0002876_abnormal_thyroid_physiology0.81730225
84MP0008872_abnormal_physiological_respon0.80348117
85MP0005394_taste/olfaction_phenotype0.80142201
86MP0005499_abnormal_olfactory_system0.80142201
87MP0003631_nervous_system_phenotype0.80032910
88MP0004142_abnormal_muscle_tone0.79656882
89MP0006292_abnormal_olfactory_placode0.79550959
90MP0002249_abnormal_larynx_morphology0.79014062
91MP0004130_abnormal_muscle_cell0.77264625
92MP0008961_abnormal_basal_metabolism0.76975211
93MP0009250_abnormal_appendicular_skeleto0.76502092
94MP0010030_abnormal_orbit_morphology0.74801178
95MP0002229_neurodegeneration0.73427394
96MP0002638_abnormal_pupillary_reflex0.72420804
97MP0003121_genomic_imprinting0.71926816
98* MP0003938_abnormal_ear_development0.71604348
99MP0005551_abnormal_eye_electrophysiolog0.71047851
100MP0002069_abnormal_eating/drinking_beha0.69603168
101MP0004885_abnormal_endolymph0.69472701
102MP0002090_abnormal_vision0.67587660
103* MP0002752_abnormal_somatic_nervous0.66411861
104* MP0000026_abnormal_inner_ear0.65805954
105MP0002653_abnormal_ependyma_morphology0.64953080
106MP0001177_atelectasis0.63861434
107MP0010769_abnormal_survival0.62894814
108MP0003634_abnormal_glial_cell0.61658414
109MP0000049_abnormal_middle_ear0.61596102
110MP0002082_postnatal_lethality0.61533448
111MP0010770_preweaning_lethality0.61533448
112MP0002089_abnormal_postnatal_growth/wei0.60998174
113MP0005645_abnormal_hypothalamus_physiol0.60540212
114MP0000534_abnormal_ureter_morphology0.60392331
115MP0003942_abnormal_urinary_system0.60114914
116MP0005171_absent_coat_pigmentation0.59029871
117MP0005166_decreased_susceptibility_to0.58992112
118MP0001485_abnormal_pinna_reflex0.58933421
119MP0010768_mortality/aging0.58446285
120* MP0002081_perinatal_lethality0.57630312
121MP0002822_catalepsy0.56870274
122MP0000762_abnormal_tongue_morphology0.55634770
123MP0003137_abnormal_impulse_conducting0.55215035
124MP0001943_abnormal_respiration0.55122883
125MP0002282_abnormal_trachea_morphology0.53479673
126* MP0003861_abnormal_nervous_system0.52901528
127MP0000538_abnormal_urinary_bladder0.52708921
128MP0008789_abnormal_olfactory_epithelium0.49478653
129MP0001663_abnormal_digestive_system0.48783562
130MP0005595_abnormal_vascular_smooth0.48426627
131MP0004085_abnormal_heartbeat0.48096958

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.95939810
2Visual hallucinations (HP:0002367)5.60753729
3Focal seizures (HP:0007359)5.46890106
4Epileptic encephalopathy (HP:0200134)4.80168167
5Atonic seizures (HP:0010819)4.54619336
6Absence seizures (HP:0002121)4.52143568
7Myokymia (HP:0002411)4.41983183
8Hyperventilation (HP:0002883)4.20426520
9Dialeptic seizures (HP:0011146)4.08077296
10Amblyopia (HP:0000646)4.04642242
11Febrile seizures (HP:0002373)4.03568868
12Broad-based gait (HP:0002136)3.91296306
13Cerebral inclusion bodies (HP:0100314)3.71709507
14Generalized tonic-clonic seizures (HP:0002069)3.71553510
15Abnormal ciliary motility (HP:0012262)3.37542925
16Ankle clonus (HP:0011448)3.35944830
17Akinesia (HP:0002304)3.18165932
18Poor eye contact (HP:0000817)3.06838423
19Abnormal respiratory motile cilium physiology (HP:0012261)3.04783475
20Supranuclear gaze palsy (HP:0000605)3.04307740
21Dynein arm defect of respiratory motile cilia (HP:0012255)3.03729801
22Absent/shortened dynein arms (HP:0200106)3.03729801
23Papilledema (HP:0001085)2.99344272
24Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.96537930
25Progressive cerebellar ataxia (HP:0002073)2.87194353
26Drooling (HP:0002307)2.81563610
27Excessive salivation (HP:0003781)2.81563610
28Inability to walk (HP:0002540)2.81405869
29Absent speech (HP:0001344)2.74125492
30Spastic gait (HP:0002064)2.73315568
31Abnormal respiratory epithelium morphology (HP:0012253)2.72822405
32Abnormal respiratory motile cilium morphology (HP:0005938)2.72822405
33Urinary bladder sphincter dysfunction (HP:0002839)2.71602793
34Stereotypic behavior (HP:0000733)2.69155993
35Annular pancreas (HP:0001734)2.67089246
36Neurofibrillary tangles (HP:0002185)2.63660910
37Turricephaly (HP:0000262)2.62435695
38Obstructive sleep apnea (HP:0002870)2.62232323
39Mutism (HP:0002300)2.60552287
40Status epilepticus (HP:0002133)2.60202828
41Focal dystonia (HP:0004373)2.51229488
42Abnormality of binocular vision (HP:0011514)2.48758917
43Diplopia (HP:0000651)2.48758917
44Inappropriate behavior (HP:0000719)2.44766998
45Urinary urgency (HP:0000012)2.44225374
46Impaired social interactions (HP:0000735)2.42168545
47Abnormal social behavior (HP:0012433)2.42168545
48Hemiparesis (HP:0001269)2.40327127
49Postural instability (HP:0002172)2.40041301
50Rhinitis (HP:0012384)2.39507294
51Protruding tongue (HP:0010808)2.36100886
52Split foot (HP:0001839)2.31989937
53Hemiplegia (HP:0002301)2.30868295
54Progressive inability to walk (HP:0002505)2.30546480
55Hyperthyroidism (HP:0000836)2.28910257
56Abnormality of the corticospinal tract (HP:0002492)2.28848356
57Gaze-evoked nystagmus (HP:0000640)2.27567147
58Anxiety (HP:0000739)2.25174632
59Craniofacial dystonia (HP:0012179)2.24115136
60Heterochromia iridis (HP:0001100)2.23819364
61Degeneration of the lateral corticospinal tracts (HP:0002314)2.22293856
62Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.22293856
63Abnormality of salivation (HP:0100755)2.21791467
64Abnormal eating behavior (HP:0100738)2.17311629
65Insomnia (HP:0100785)2.17002331
66Lower limb asymmetry (HP:0100559)2.16923456
67Broad metatarsal (HP:0001783)2.16178584
68Septo-optic dysplasia (HP:0100842)2.15688367
69Truncal ataxia (HP:0002078)2.15392203
70Concave nail (HP:0001598)2.12863226
71Partial duplication of thumb phalanx (HP:0009944)2.12446817
72Widely spaced teeth (HP:0000687)2.10759556
73Hydroureter (HP:0000072)2.10612241
74Depression (HP:0000716)2.08261987
75Ankyloglossia (HP:0010296)2.07041497
76Partial duplication of the phalanx of hand (HP:0009999)2.06180505
77Dysdiadochokinesis (HP:0002075)2.05230332
78Retinal dysplasia (HP:0007973)2.05114769
79Hypoventilation (HP:0002791)2.03989075
80Action tremor (HP:0002345)2.03377883
81Exotropia (HP:0000577)2.00957804
82Rapidly progressive (HP:0003678)1.99231905
83Generalized myoclonic seizures (HP:0002123)1.98853221
84Dysmetria (HP:0001310)1.97442867
85Overriding aorta (HP:0002623)1.94744435
86Neuronal loss in central nervous system (HP:0002529)1.94413931
87Intention tremor (HP:0002080)1.92510256
88Thickened helices (HP:0000391)1.92407512
89Hypsarrhythmia (HP:0002521)1.91961364
90Buphthalmos (HP:0000557)1.91946484
91Lower limb amyotrophy (HP:0007210)1.91182553
92Megalencephaly (HP:0001355)1.90162841
93Abnormality of oral frenula (HP:0000190)1.89598956
94Epileptiform EEG discharges (HP:0011182)1.89437035
95Apathy (HP:0000741)1.89322556
96Aplasia involving bones of the upper limbs (HP:0009823)1.87974741
97Aplasia of the phalanges of the hand (HP:0009802)1.87974741
98Aplasia involving bones of the extremities (HP:0009825)1.87974741
99Progressive macrocephaly (HP:0004481)1.85718153
100Morphological abnormality of the middle ear (HP:0008609)1.84390776
101Long nose (HP:0003189)1.82851856
102Lower limb muscle weakness (HP:0007340)1.81263596
103Delusions (HP:0000746)1.80822977
104Type II lissencephaly (HP:0007260)1.80132963
105Chronic sinusitis (HP:0011109)1.78875409
106Insidious onset (HP:0003587)1.78549209
107Termporal pattern (HP:0011008)1.78549209
108Coronal craniosynostosis (HP:0004440)1.77800684
109Gait imbalance (HP:0002141)1.77381392
110Incomplete penetrance (HP:0003829)1.76243230
111Polyphagia (HP:0002591)1.75244627
112Bronchomalacia (HP:0002780)1.73148447
113J-shaped sella turcica (HP:0002680)1.73013972
114Morphological abnormality of the pyramidal tract (HP:0002062)1.72226739
115Impaired vibration sensation in the lower limbs (HP:0002166)1.71826288
116Spastic tetraparesis (HP:0001285)1.71673190
117Palpebral edema (HP:0100540)1.71607916
118Limb dystonia (HP:0002451)1.71478421
119Diminished motivation (HP:0000745)1.71213231
120Cerebral hypomyelination (HP:0006808)1.69057207
121Shoulder girdle muscle weakness (HP:0003547)1.68910086
122Tetraplegia (HP:0002445)1.68793116
123Shallow orbits (HP:0000586)1.68662202
124Choanal stenosis (HP:0000452)1.68337626
125Rigidity (HP:0002063)1.68270747
126Impaired smooth pursuit (HP:0007772)1.68097699
127EEG with generalized epileptiform discharges (HP:0011198)1.67432239
128Sleep apnea (HP:0010535)1.66853695
129Acute necrotizing encephalopathy (HP:0006965)1.66525484
130Clumsiness (HP:0002312)1.65601139
131Fetal akinesia sequence (HP:0001989)1.65490808
132Macroglossia (HP:0000158)1.65025334
133Clonus (HP:0002169)1.64191998
134Deeply set eye (HP:0000490)1.63778474
135Torticollis (HP:0000473)1.61458791
136Abnormality of the diencephalon (HP:0010662)1.61329792
137Bradykinesia (HP:0002067)1.61126521
138Ventricular fibrillation (HP:0001663)1.61091617
139Fair hair (HP:0002286)1.61041808
140Peripheral hypomyelination (HP:0007182)1.56085518
141Prolonged QT interval (HP:0001657)1.55900446

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.50920329
2RIPK44.82548873
3NTRK33.76213037
4MAP3K93.41706770
5MAP3K122.98809485
6CASK2.87512013
7DAPK22.81596543
8PLK22.63622381
9MAP3K42.59362440
10PNCK2.53768684
11MAP2K72.52091288
12SIK22.36704758
13MINK12.20534000
14MARK12.20491843
15FGR2.15945954
16BMPR21.88864226
17DAPK11.86928586
18KSR21.81968039
19GRK51.70479999
20KSR11.68332272
21FES1.67645413
22PTK2B1.56389927
23MAP2K41.56156705
24NME11.53996250
25GRK61.52115162
26PAK61.46365681
27NTRK21.33588954
28CDK51.28034187
29DYRK21.26619395
30MAP3K111.23670219
31PINK11.21677194
32MAPK131.21294553
33SGK4941.20729616
34SGK2231.20729616
35MAP3K131.18632244
36TNIK1.11349905
37CDK191.10251701
38ARAF1.09228323
39PKN11.08683505
40CAMK2A1.05749914
41RAF11.04597366
42PRKCG1.04290542
43CAMKK11.03716418
44TAOK11.00731495
45DYRK1A0.99274801
46MAPK150.99214494
47MAP3K20.99035377
48LATS20.98594482
49NTRK10.94426392
50SGK20.88709902
51DAPK30.85327718
52CAMK2G0.84603666
53CAMKK20.83654943
54WNK30.80764172
55CAMK2B0.75185775
56TYRO30.74720184
57PRKCH0.73941598
58BLK0.73681983
59RIPK10.72243951
60CAMK10.69773668
61PRKCE0.67237196
62CDK140.66547056
63CCNB10.65526156
64ROCK20.63653034
65PRPF4B0.63119237
66STK380.62311001
67ALK0.61712771
68STK110.61301400
69FER0.60376945
70CDK180.60013034
71CDK150.58950838
72SGK10.58610780
73SGK30.58112088
74TESK10.57895848
75LIMK10.56784028
76FYN0.56403578
77SYK0.54716698
78ADRBK10.54711726
79MAP2K10.54276734
80FRK0.53870725
81CDK11A0.53225182
82CAMK1G0.53151770
83MAPKAPK50.49839452
84DMPK0.49798151
85MUSK0.49170513
86UHMK10.48591937
87MAPK120.48444727
88BRAF0.46553265
89PDPK10.46000207
90PRKCZ0.45909408
91RET0.45785153
92MAPK100.45687012
93OXSR10.45273847
94PDGFRA0.44953159
95MARK20.43803938
96CAMK40.43340347
97PRKD20.40817110
98DDR20.40387433
99PHKG10.40004152
100PHKG20.40004152
101CDK30.39927913
102ABL20.39666232
103TRIB30.39480694
104BRSK10.39144358
105CSNK1E0.39009460
106MAPK40.38412949
107FGFR20.38255654
108MAP3K10.38015877
109MOS0.38015443
110TNK20.37687937
111EPHB20.37214372
112CSNK1G20.34062940
113PAK30.33567612
114ERBB20.33230587
115CAMK2D0.33007799
116NEK60.32207737
117GRK70.31955439
118MAP3K60.30130646
119PRKG10.29163736
120PRKCQ0.28730324
121PDK10.27829406
122PRKD30.27679683
123MAPK80.27322963
124MST40.26027059
125MYLK0.25677065
126MAP3K50.24497600
127SRC0.23818849
128MAP3K70.23211469
129PRKACA0.22786891
130PRKCA0.21887516
131RPS6KA30.21267704
132TLK10.20871882

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.47014129
2Long-term potentiation_Homo sapiens_hsa047202.64151849
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.55792725
4Synaptic vesicle cycle_Homo sapiens_hsa047212.43001789
5Glutamatergic synapse_Homo sapiens_hsa047242.34552871
6Circadian entrainment_Homo sapiens_hsa047132.29286768
7Amphetamine addiction_Homo sapiens_hsa050312.21096147
8Salivary secretion_Homo sapiens_hsa049702.17181208
9Morphine addiction_Homo sapiens_hsa050322.15005795
10Olfactory transduction_Homo sapiens_hsa047402.06792130
11GABAergic synapse_Homo sapiens_hsa047271.99119499
12Renin secretion_Homo sapiens_hsa049241.96881448
13Collecting duct acid secretion_Homo sapiens_hsa049661.94320495
14Dopaminergic synapse_Homo sapiens_hsa047281.88941930
15Gastric acid secretion_Homo sapiens_hsa049711.88799974
16Oxytocin signaling pathway_Homo sapiens_hsa049211.73705803
17Long-term depression_Homo sapiens_hsa047301.69006493
18Serotonergic synapse_Homo sapiens_hsa047261.68174663
19Cholinergic synapse_Homo sapiens_hsa047251.65670464
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.64699066
21Calcium signaling pathway_Homo sapiens_hsa040201.55781205
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.53544138
23Oxidative phosphorylation_Homo sapiens_hsa001901.50646867
24GnRH signaling pathway_Homo sapiens_hsa049121.48309023
25Taste transduction_Homo sapiens_hsa047421.48043282
26Alzheimers disease_Homo sapiens_hsa050101.44126426
27Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.39576998
28Gap junction_Homo sapiens_hsa045401.36005978
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.35060189
30Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.32462912
31Insulin secretion_Homo sapiens_hsa049111.29878584
32Cocaine addiction_Homo sapiens_hsa050301.26771578
33Cardiac muscle contraction_Homo sapiens_hsa042601.26604657
34Axon guidance_Homo sapiens_hsa043601.22875971
35Glioma_Homo sapiens_hsa052141.17895713
36African trypanosomiasis_Homo sapiens_hsa051431.16573107
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15041678
38Vibrio cholerae infection_Homo sapiens_hsa051101.11800783
39Estrogen signaling pathway_Homo sapiens_hsa049151.11482294
40cAMP signaling pathway_Homo sapiens_hsa040241.10586347
41Melanogenesis_Homo sapiens_hsa049161.10443288
42Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.09776474
43Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.08463766
44Parkinsons disease_Homo sapiens_hsa050121.03640157
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.02381771
46cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00854693
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.00145648
48Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.99226914
49VEGF signaling pathway_Homo sapiens_hsa043700.98901445
50Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.94854062
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91755809
52Phototransduction_Homo sapiens_hsa047440.88560193
53Rheumatoid arthritis_Homo sapiens_hsa053230.87347483
54ErbB signaling pathway_Homo sapiens_hsa040120.87073970
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.86324573
56Huntingtons disease_Homo sapiens_hsa050160.82503925
57Hippo signaling pathway_Homo sapiens_hsa043900.79842320
58Pancreatic secretion_Homo sapiens_hsa049720.78676467
59Sphingolipid signaling pathway_Homo sapiens_hsa040710.77014215
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.76887623
61Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.76710402
62MAPK signaling pathway_Homo sapiens_hsa040100.73099492
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.72528458
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70326950
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.69302961
66Dorso-ventral axis formation_Homo sapiens_hsa043200.68424355
67Vitamin B6 metabolism_Homo sapiens_hsa007500.68414183
68Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.68164468
69Tuberculosis_Homo sapiens_hsa051520.66945656
70Type II diabetes mellitus_Homo sapiens_hsa049300.66743920
71Dilated cardiomyopathy_Homo sapiens_hsa054140.66122111
72Choline metabolism in cancer_Homo sapiens_hsa052310.66118697
73Oocyte meiosis_Homo sapiens_hsa041140.64832165
74Osteoclast differentiation_Homo sapiens_hsa043800.64725402
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64541163
76Salmonella infection_Homo sapiens_hsa051320.64400059
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63892469
78Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63495201
79Bile secretion_Homo sapiens_hsa049760.62994214
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.62141944
81Rap1 signaling pathway_Homo sapiens_hsa040150.61405273
82Asthma_Homo sapiens_hsa053100.61170152
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.60591289
84Basal cell carcinoma_Homo sapiens_hsa052170.60380492
85Hedgehog signaling pathway_Homo sapiens_hsa043400.59959508
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59798145
87B cell receptor signaling pathway_Homo sapiens_hsa046620.59535738
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58941246
89Thyroid hormone synthesis_Homo sapiens_hsa049180.58803226
90AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57861632
91Ras signaling pathway_Homo sapiens_hsa040140.57677300
92Phagosome_Homo sapiens_hsa041450.57408847
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.55892005
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55240577
95Wnt signaling pathway_Homo sapiens_hsa043100.55113607
96Renal cell carcinoma_Homo sapiens_hsa052110.54000067
97Tight junction_Homo sapiens_hsa045300.53924803
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53608018
99Chemokine signaling pathway_Homo sapiens_hsa040620.52366710
100Prion diseases_Homo sapiens_hsa050200.48815541
101Platelet activation_Homo sapiens_hsa046110.48679486
102Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47390831
103Histidine metabolism_Homo sapiens_hsa003400.47195079
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45066141
105T cell receptor signaling pathway_Homo sapiens_hsa046600.43226751
106Pertussis_Homo sapiens_hsa051330.43101683
107Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42146194
108Leishmaniasis_Homo sapiens_hsa051400.41995887
109Melanoma_Homo sapiens_hsa052180.41550463
110Alcoholism_Homo sapiens_hsa050340.40360039
111Non-small cell lung cancer_Homo sapiens_hsa052230.40042854
112Amoebiasis_Homo sapiens_hsa051460.39547005
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38911950
114Mineral absorption_Homo sapiens_hsa049780.38781794
115Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38269169
116Protein digestion and absorption_Homo sapiens_hsa049740.37382712
117Glucagon signaling pathway_Homo sapiens_hsa049220.34110107
118Prolactin signaling pathway_Homo sapiens_hsa049170.32778843
119Ribosome_Homo sapiens_hsa030100.32498465
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.32458882
121Folate biosynthesis_Homo sapiens_hsa007900.32417700
122Endometrial cancer_Homo sapiens_hsa052130.31582459
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.30721401

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