Rank | Gene Set | Z-score |
---|---|---|
1 | aminoglycoside antibiotic metabolic process (GO:0030647) | 9.79341801 |
2 | drug transport (GO:0015893) | 8.83521929 |
3 | phosphate ion transport (GO:0006817) | 8.69294775 |
4 | lysine metabolic process (GO:0006553) | 8.65305108 |
5 | lysine catabolic process (GO:0006554) | 8.65305108 |
6 | organic cation transport (GO:0015695) | 8.63707952 |
7 | phosphate ion transmembrane transport (GO:0035435) | 7.55784232 |
8 | excretion (GO:0007588) | 6.75178053 |
9 | quaternary ammonium group transport (GO:0015697) | 6.66047475 |
10 | cysteine metabolic process (GO:0006534) | 6.60770065 |
11 | response to mercury ion (GO:0046689) | 6.15266079 |
12 | renal absorption (GO:0070293) | 6.05841842 |
13 | drug catabolic process (GO:0042737) | 5.99619231 |
14 | glyoxylate metabolic process (GO:0046487) | 5.85034616 |
15 | tricarboxylic acid metabolic process (GO:0072350) | 5.72833538 |
16 | toxin transport (GO:1901998) | 5.66508451 |
17 | modified amino acid transport (GO:0072337) | 5.66240958 |
18 | metanephric tubule development (GO:0072170) | 5.60718753 |
19 | metanephric nephron tubule development (GO:0072234) | 5.60718753 |
20 | aspartate family amino acid catabolic process (GO:0009068) | 5.60485544 |
21 | exogenous drug catabolic process (GO:0042738) | 5.52523141 |
22 | nonribosomal peptide biosynthetic process (GO:0019184) | 5.43912549 |
23 | trivalent inorganic anion homeostasis (GO:0072506) | 5.36714869 |
24 | phosphate ion homeostasis (GO:0055062) | 5.36714869 |
25 | metanephric nephron epithelium development (GO:0072243) | 5.19510719 |
26 | homocysteine metabolic process (GO:0050667) | 5.16827627 |
27 | amino-acid betaine transport (GO:0015838) | 4.98410860 |
28 | carnitine transport (GO:0015879) | 4.98410860 |
29 | glutathione biosynthetic process (GO:0006750) | 4.87663313 |
30 | vitamin transport (GO:0051180) | 4.84578742 |
31 | short-chain fatty acid metabolic process (GO:0046459) | 4.84531917 |
32 | branched-chain amino acid metabolic process (GO:0009081) | 4.81752585 |
33 | valine metabolic process (GO:0006573) | 4.78356379 |
34 | metanephric epithelium development (GO:0072207) | 4.76118258 |
35 | serine family amino acid metabolic process (GO:0009069) | 4.75125163 |
36 | serine family amino acid catabolic process (GO:0009071) | 4.61249746 |
37 | 2-oxoglutarate metabolic process (GO:0006103) | 4.60301487 |
38 | lateral sprouting from an epithelium (GO:0060601) | 4.53092343 |
39 | neuronal stem cell maintenance (GO:0097150) | 4.51520428 |
40 | peptide catabolic process (GO:0043171) | 4.50283994 |
41 | fructose metabolic process (GO:0006000) | 4.49655612 |
42 | indole-containing compound catabolic process (GO:0042436) | 4.46194751 |
43 | indolalkylamine catabolic process (GO:0046218) | 4.46194751 |
44 | tryptophan catabolic process (GO:0006569) | 4.46194751 |
45 | proline metabolic process (GO:0006560) | 4.40063304 |
46 | * vitamin D metabolic process (GO:0042359) | 4.35125054 |
47 | amino-acid betaine metabolic process (GO:0006577) | 4.33515976 |
48 | nephron tubule development (GO:0072080) | 4.30170514 |
49 | glycoside metabolic process (GO:0016137) | 4.29403026 |
50 | tryptophan metabolic process (GO:0006568) | 4.23692313 |
51 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.20058791 |
52 | aromatic amino acid family catabolic process (GO:0009074) | 4.18647995 |
53 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 4.17617348 |
54 | paraxial mesoderm development (GO:0048339) | 4.14986960 |
55 | cellular modified amino acid catabolic process (GO:0042219) | 4.13897039 |
56 | surfactant homeostasis (GO:0043129) | 4.11348426 |
57 | acetyl-CoA metabolic process (GO:0006084) | 4.10028190 |
58 | polyol transport (GO:0015791) | 4.09862332 |
59 | central nervous system myelination (GO:0022010) | 4.09440763 |
60 | axon ensheathment in central nervous system (GO:0032291) | 4.09440763 |
61 | oligosaccharide catabolic process (GO:0009313) | 4.06881401 |
62 | fatty acid beta-oxidation (GO:0006635) | 4.00246689 |
63 | serine family amino acid biosynthetic process (GO:0009070) | 3.99693164 |
64 | response to phenylpropanoid (GO:0080184) | 3.96997820 |
65 | carnitine metabolic process (GO:0009437) | 3.94763839 |
66 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.94376899 |
67 | branched-chain amino acid catabolic process (GO:0009083) | 3.93912317 |
68 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.93080027 |
69 | cobalamin metabolic process (GO:0009235) | 3.87071089 |
70 | limb bud formation (GO:0060174) | 3.84963566 |
71 | peptide biosynthetic process (GO:0043043) | 3.83654452 |
72 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.83329794 |
73 | L-phenylalanine metabolic process (GO:0006558) | 3.83329794 |
74 | sulfur compound transport (GO:0072348) | 3.83267140 |
75 | L-ascorbic acid metabolic process (GO:0019852) | 3.80242711 |
76 | notochord development (GO:0030903) | 3.80085480 |
77 | glutamate metabolic process (GO:0006536) | 3.79018471 |
78 | renal tubule development (GO:0061326) | 3.75287989 |
79 | presynaptic membrane organization (GO:0097090) | 3.73395638 |
80 | fatty acid oxidation (GO:0019395) | 3.71305216 |
81 | sodium-independent organic anion transport (GO:0043252) | 3.71008706 |
82 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.69246684 |
83 | regulation of hippo signaling (GO:0035330) | 3.66059181 |
84 | lung-associated mesenchyme development (GO:0060484) | 3.65909634 |
85 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.65775993 |
86 | L-phenylalanine catabolic process (GO:0006559) | 3.65775993 |
87 | lipid oxidation (GO:0034440) | 3.63476367 |
88 | kynurenine metabolic process (GO:0070189) | 3.62833975 |
89 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.61897687 |
90 | limb development (GO:0060173) | 3.61579629 |
91 | appendage development (GO:0048736) | 3.61579629 |
92 | presynaptic membrane assembly (GO:0097105) | 3.60337751 |
93 | retinal ganglion cell axon guidance (GO:0031290) | 3.54693929 |
94 | folic acid metabolic process (GO:0046655) | 3.52556818 |
95 | axonal fasciculation (GO:0007413) | 3.51583907 |
96 | response to growth hormone (GO:0060416) | 3.51040323 |
97 | nephron epithelium development (GO:0072009) | 3.44412405 |
98 | convergent extension (GO:0060026) | 3.42268981 |
99 | glutathione derivative biosynthetic process (GO:1901687) | 3.39269458 |
100 | glutathione derivative metabolic process (GO:1901685) | 3.39269458 |
101 | response to parathyroid hormone (GO:0071107) | 3.38523542 |
102 | dorsal/ventral axis specification (GO:0009950) | 3.37469872 |
103 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.37083724 |
104 | cellular amino acid catabolic process (GO:0009063) | 3.35709902 |
105 | cellular response to vitamin D (GO:0071305) | 3.33724634 |
106 | sodium ion transport (GO:0006814) | 3.33399120 |
107 | apical protein localization (GO:0045176) | 3.29585005 |
108 | nephron tubule morphogenesis (GO:0072078) | 3.28049231 |
109 | nephron epithelium morphogenesis (GO:0072088) | 3.28049231 |
110 | cellular ketone body metabolic process (GO:0046950) | 3.27608399 |
111 | alpha-amino acid catabolic process (GO:1901606) | 3.27399490 |
112 | NADH metabolic process (GO:0006734) | 3.24654993 |
113 | folic acid transport (GO:0015884) | 3.22287587 |
114 | glutathione metabolic process (GO:0006749) | 3.20416113 |
115 | negative regulation of astrocyte differentiation (GO:0048712) | 3.19473430 |
116 | establishment of nucleus localization (GO:0040023) | 3.17420612 |
117 | indole-containing compound metabolic process (GO:0042430) | 3.17228909 |
118 | biotin metabolic process (GO:0006768) | 3.16657702 |
119 | dicarboxylic acid metabolic process (GO:0043648) | 3.15904853 |
120 | fatty acid catabolic process (GO:0009062) | 3.15536895 |
121 | aromatic amino acid family metabolic process (GO:0009072) | 3.15323833 |
122 | mesenchymal to epithelial transition (GO:0060231) | 3.10683973 |
123 | vitamin transmembrane transport (GO:0035461) | 3.09318295 |
124 | hyperosmotic salinity response (GO:0042538) | 3.07083484 |
125 | branching involved in salivary gland morphogenesis (GO:0060445) | 3.02221174 |
126 | cell proliferation in forebrain (GO:0021846) | 3.01011426 |
127 | neuron recognition (GO:0008038) | 2.99526710 |
128 | establishment of planar polarity (GO:0001736) | 2.98968410 |
129 | establishment of tissue polarity (GO:0007164) | 2.98968410 |
130 | postsynaptic membrane organization (GO:0001941) | 2.95949243 |
131 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.95188064 |
132 | somite development (GO:0061053) | 2.94345977 |
133 | lens fiber cell development (GO:0070307) | 2.94270412 |
134 | nephron tubule formation (GO:0072079) | 2.93934872 |
135 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.93832994 |
136 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.90811667 |
137 | axon extension involved in axon guidance (GO:0048846) | 2.90811667 |
138 | asymmetric protein localization (GO:0008105) | 2.90054553 |
139 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.86569163 |
140 | nonmotile primary cilium assembly (GO:0035058) | 2.86329171 |
141 | radial glial cell differentiation (GO:0060019) | 2.85916127 |
142 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 2.85152172 |
143 | negative chemotaxis (GO:0050919) | 2.83912674 |
144 | camera-type eye morphogenesis (GO:0048593) | 2.83426358 |
145 | non-canonical Wnt signaling pathway (GO:0035567) | 2.83350248 |
146 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.82660947 |
147 | olfactory bulb development (GO:0021772) | 2.82009964 |
148 | cranial nerve development (GO:0021545) | 2.81717533 |
149 | nucleobase catabolic process (GO:0046113) | 2.79317502 |
150 | ephrin receptor signaling pathway (GO:0048013) | 2.78962978 |
151 | cell migration in hindbrain (GO:0021535) | 2.78912117 |
152 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.77128154 |
153 | cardiovascular system development (GO:0072358) | 2.76581698 |
154 | pre-miRNA processing (GO:0031054) | 2.75512872 |
155 | regulation of establishment of planar polarity (GO:0090175) | 2.74740164 |
156 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.74533578 |
157 | glomerulus development (GO:0032835) | 2.74192322 |
158 | genitalia morphogenesis (GO:0035112) | 2.72838802 |
159 | negative regulation of glial cell differentiation (GO:0045686) | 2.70717003 |
160 | negative regulation of axon guidance (GO:1902668) | 2.70698508 |
161 | spinal cord development (GO:0021510) | 2.69472193 |
162 | inner ear morphogenesis (GO:0042472) | 2.66577857 |
163 | short-term memory (GO:0007614) | 2.65606215 |
164 | pattern specification involved in kidney development (GO:0061004) | 2.65566315 |
165 | morphogenesis of an epithelial sheet (GO:0002011) | 2.64072237 |
166 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.59747198 |
167 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.58665433 |
168 | otic vesicle formation (GO:0030916) | 2.56213240 |
169 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.53969303 |
170 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.52056979 |
171 | neuron fate determination (GO:0048664) | 2.50672392 |
172 | embryonic foregut morphogenesis (GO:0048617) | 2.45887195 |
173 | hippo signaling (GO:0035329) | 2.44075213 |
174 | regulation of astrocyte differentiation (GO:0048710) | 2.43666797 |
175 | midbrain development (GO:0030901) | 2.42177270 |
176 | gastrulation with mouth forming second (GO:0001702) | 2.41602801 |
177 | intraciliary transport (GO:0042073) | 2.40708710 |
178 | positive regulation of mesonephros development (GO:0061213) | 2.39715436 |
179 | positive regulation of neuroblast proliferation (GO:0002052) | 2.38798499 |
180 | regulation of gene silencing by RNA (GO:0060966) | 2.38767579 |
181 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.38767579 |
182 | regulation of gene silencing by miRNA (GO:0060964) | 2.38767579 |
183 | pituitary gland development (GO:0021983) | 2.38647226 |
184 | auditory receptor cell differentiation (GO:0042491) | 2.37277907 |
185 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.36682284 |
186 | cell-cell signaling involved in cell fate commitment (GO:0045168) | 2.34775074 |
187 | tongue development (GO:0043586) | 2.34652736 |
188 | developmental induction (GO:0031128) | 2.33839962 |
189 | transmission of nerve impulse (GO:0019226) | 2.32746854 |
190 | collecting duct development (GO:0072044) | 2.32190986 |
191 | positive regulation of catenin import into nucleus (GO:0035413) | 2.31547935 |
192 | cerebral cortex development (GO:0021987) | 2.31315360 |
193 | thyroid hormone generation (GO:0006590) | 2.31291304 |
194 | artery development (GO:0060840) | 2.31282831 |
195 | inner ear receptor stereocilium organization (GO:0060122) | 2.31227048 |
196 | urate metabolic process (GO:0046415) | 10.8514709 |
197 | drug transmembrane transport (GO:0006855) | 10.2058850 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 4.78676930 |
2 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 4.44909002 |
3 | AR_21909140_ChIP-Seq_LNCAP_Human | 4.32696854 |
4 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.09492245 |
5 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 3.87619679 |
6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.75253753 |
7 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.68402274 |
8 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 3.49013442 |
9 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.31746491 |
10 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.13938603 |
11 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.96876141 |
12 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.76250050 |
13 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.75724474 |
14 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.75453331 |
15 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.69601560 |
16 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.66659139 |
17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.65915892 |
18 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.64112304 |
19 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.61661315 |
20 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.58891055 |
21 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.49809063 |
22 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.39971854 |
23 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 2.37444226 |
24 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 2.37180670 |
25 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 2.36115930 |
26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.35824207 |
27 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.29825009 |
28 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.26819405 |
29 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 2.24802710 |
30 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 2.14764288 |
31 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.09687738 |
32 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 2.04247434 |
33 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.02782074 |
34 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.01708483 |
35 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 2.01287443 |
36 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.97956863 |
37 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.97737941 |
38 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.97112466 |
39 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.94379572 |
40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.91465702 |
41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.90065033 |
42 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.89280947 |
43 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.88255358 |
44 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.86801002 |
45 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.85328998 |
46 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.84996795 |
47 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.83744123 |
48 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.81875177 |
49 | VDR_22108803_ChIP-Seq_LS180_Human | 1.80892015 |
50 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.80518834 |
51 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.80500754 |
52 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.80042335 |
53 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.77050280 |
54 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.76752617 |
55 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.75534890 |
56 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.73686387 |
57 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.73386925 |
58 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.73311136 |
59 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.70440102 |
60 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 1.70212366 |
61 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.70190427 |
62 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.68149565 |
63 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.65834754 |
64 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.63158534 |
65 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.62552313 |
66 | EWS_26573619_Chip-Seq_HEK293_Human | 1.61907024 |
67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.61693954 |
68 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.60456940 |
69 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.60365994 |
70 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.59028385 |
71 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.57187466 |
72 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.57187466 |
73 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.55860501 |
74 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.55818857 |
75 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.54939918 |
76 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.53833363 |
77 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.52814937 |
78 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.52120994 |
79 | * SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.51886235 |
80 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.50726727 |
81 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.50708758 |
82 | * NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.48937026 |
83 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.47321135 |
84 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.46582879 |
85 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.45594999 |
86 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.42847898 |
87 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.42167860 |
88 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.41295579 |
89 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.41245451 |
90 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.40058266 |
91 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39366320 |
92 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.39366320 |
93 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.39047238 |
94 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.37698523 |
95 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.36647630 |
96 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.36160566 |
97 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35943639 |
98 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.35884742 |
99 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35765624 |
100 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.35460743 |
101 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.35426945 |
102 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.33568896 |
103 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.32904856 |
104 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.32532964 |
105 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.31943911 |
106 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.31609611 |
107 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.29616715 |
108 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.29437781 |
109 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.29171906 |
110 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.29077536 |
111 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.28651393 |
112 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.28324058 |
113 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.27528081 |
114 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.26600327 |
115 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.26485583 |
116 | * CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.26302642 |
117 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.25310756 |
118 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.24878115 |
119 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.24636200 |
120 | * KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.24526519 |
121 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.23497712 |
122 | * SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.23466981 |
123 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.23347431 |
124 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.23223394 |
125 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.22623469 |
126 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.22390433 |
127 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.21699041 |
128 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.20782100 |
129 | * TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.20667397 |
130 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.20626292 |
131 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.20463086 |
132 | * TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.19659626 |
133 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.19104111 |
134 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.18340765 |
135 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18303616 |
136 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.17993586 |
137 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.17491386 |
138 | STAT3_23295773_ChIP-Seq_U87_Human | 1.16898202 |
139 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.16665815 |
140 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.16574765 |
141 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.16501196 |
142 | * TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.16498966 |
143 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.15381405 |
144 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.15189095 |
145 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.14669001 |
146 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 1.14320751 |
147 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 1.13986665 |
148 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.12464959 |
149 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.11736453 |
150 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11241043 |
151 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11241043 |
152 | ATF3_27146783_Chip-Seq_COLON_Human | 1.11088664 |
153 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.10947556 |
154 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.10681608 |
155 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.10066112 |
156 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.10008164 |
157 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.09999358 |
158 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.08576258 |
159 | * NANOG_18692474_ChIP-Seq_MESCs_Mouse | 1.08418740 |
160 | AR_25329375_ChIP-Seq_VCAP_Human | 1.07780121 |
161 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.07382989 |
162 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07237317 |
163 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.07086635 |
164 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.06137336 |
165 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.05966634 |
166 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 1.05668429 |
167 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.05555065 |
168 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.04976540 |
169 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.04139584 |
170 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.03364782 |
171 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.01062671 |
172 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.01062671 |
173 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.01062671 |
174 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.99568393 |
175 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.99568393 |
176 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.98288991 |
177 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.97707672 |
178 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.95594642 |
179 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.94056242 |
180 | RXR_22108803_ChIP-Seq_LS180_Human | 0.92832489 |
181 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.90951494 |
182 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.86710034 |
183 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.85666022 |
184 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.85555691 |
185 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.85528852 |
186 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.84881226 |
187 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.84731676 |
188 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84688793 |
189 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.84400720 |
190 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.84343170 |
191 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.82293755 |
192 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.81809901 |
193 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.79168863 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 7.45352840 |
2 | MP0004043_abnormal_pH_regulation | 6.53259569 |
3 | MP0005332_abnormal_amino_acid | 4.86558777 |
4 | * MP0004019_abnormal_vitamin_homeostasis | 4.68533388 |
5 | MP0003195_calcinosis | 4.34812009 |
6 | MP0002138_abnormal_hepatobiliary_system | 4.31724841 |
7 | * MP0009643_abnormal_urine_homeostasis | 3.97397864 |
8 | MP0002139_abnormal_hepatobiliary_system | 3.71398640 |
9 | MP0001756_abnormal_urination | 3.48378029 |
10 | MP0000566_synostosis | 3.41122936 |
11 | * MP0001765_abnormal_ion_homeostasis | 3.40943647 |
12 | * MP0002136_abnormal_kidney_physiology | 3.13765632 |
13 | MP0003136_yellow_coat_color | 3.02891495 |
14 | MP0010030_abnormal_orbit_morphology | 2.91524653 |
15 | MP0006292_abnormal_olfactory_placode | 2.79490500 |
16 | MP0003122_maternal_imprinting | 2.72750397 |
17 | * MP0005636_abnormal_mineral_homeostasis | 2.69874018 |
18 | * MP0000778_abnormal_nervous_system | 2.58998787 |
19 | * MP0001293_anophthalmia | 2.53565465 |
20 | MP0005248_abnormal_Harderian_gland | 2.52876034 |
21 | MP0002938_white_spotting | 2.38799540 |
22 | MP0008875_abnormal_xenobiotic_pharmacok | 2.38545901 |
23 | MP0004264_abnormal_extraembryonic_tissu | 2.27112094 |
24 | MP0003252_abnormal_bile_duct | 2.26090718 |
25 | MP0005058_abnormal_lysosome_morphology | 2.12431994 |
26 | MP0000383_abnormal_hair_follicle | 2.05533756 |
27 | MP0003937_abnormal_limbs/digits/tail_de | 1.96596091 |
28 | MP0001346_abnormal_lacrimal_gland | 1.96361563 |
29 | MP0003938_abnormal_ear_development | 1.95515047 |
30 | MP0005365_abnormal_bile_salt | 1.93911031 |
31 | MP0003880_abnormal_central_pattern | 1.82715657 |
32 | MP0002233_abnormal_nose_morphology | 1.82071839 |
33 | MP0004272_abnormal_basement_membrane | 1.77895533 |
34 | MP0001286_abnormal_eye_development | 1.76428571 |
35 | MP0003186_abnormal_redox_activity | 1.71309933 |
36 | MP0008961_abnormal_basal_metabolism | 1.69720208 |
37 | MP0010234_abnormal_vibrissa_follicle | 1.66491741 |
38 | MP0000538_abnormal_urinary_bladder | 1.63465380 |
39 | * MP0001958_emphysema | 1.63274092 |
40 | MP0006072_abnormal_retinal_apoptosis | 1.62317084 |
41 | MP0004859_abnormal_synaptic_plasticity | 1.62191282 |
42 | MP0001486_abnormal_startle_reflex | 1.61332268 |
43 | MP0002168_other_aberrant_phenotype | 1.60762779 |
44 | MP0003283_abnormal_digestive_organ | 1.59234970 |
45 | MP0002653_abnormal_ependyma_morphology | 1.58133120 |
46 | MP0005085_abnormal_gallbladder_physiolo | 1.57318172 |
47 | MP0000647_abnormal_sebaceous_gland | 1.55891488 |
48 | MP0004885_abnormal_endolymph | 1.53609918 |
49 | MP0000631_abnormal_neuroendocrine_gland | 1.53506985 |
50 | MP0003300_gastrointestinal_ulcer | 1.49636792 |
51 | MP0001299_abnormal_eye_distance/ | 1.46001773 |
52 | MP0010678_abnormal_skin_adnexa | 1.45765003 |
53 | MP0000049_abnormal_middle_ear | 1.44862634 |
54 | MP0003941_abnormal_skin_development | 1.41603987 |
55 | MP0005253_abnormal_eye_physiology | 1.40952763 |
56 | * MP0000026_abnormal_inner_ear | 1.40664204 |
57 | MP0003121_genomic_imprinting | 1.39950413 |
58 | MP0005084_abnormal_gallbladder_morpholo | 1.39906864 |
59 | MP0002928_abnormal_bile_duct | 1.39834787 |
60 | * MP0005391_vision/eye_phenotype | 1.37881081 |
61 | MP0000428_abnormal_craniofacial_morphol | 1.37184885 |
62 | MP0003806_abnormal_nucleotide_metabolis | 1.35376018 |
63 | * MP0002092_abnormal_eye_morphology | 1.35163537 |
64 | MP0001984_abnormal_olfaction | 1.34938749 |
65 | MP0003567_abnormal_fetal_cardiomyocyte | 1.34299004 |
66 | * MP0003861_abnormal_nervous_system | 1.30935551 |
67 | * MP0002135_abnormal_kidney_morphology | 1.29931592 |
68 | MP0004270_analgesia | 1.29470743 |
69 | MP0008789_abnormal_olfactory_epithelium | 1.28168450 |
70 | MP0005499_abnormal_olfactory_system | 1.25772040 |
71 | MP0005394_taste/olfaction_phenotype | 1.25772040 |
72 | MP0002184_abnormal_innervation | 1.25440872 |
73 | MP0000955_abnormal_spinal_cord | 1.25194967 |
74 | MP0005171_absent_coat_pigmentation | 1.23862951 |
75 | MP0002638_abnormal_pupillary_reflex | 1.22324002 |
76 | MP0003385_abnormal_body_wall | 1.21743240 |
77 | MP0002557_abnormal_social/conspecific_i | 1.21274301 |
78 | MP0003755_abnormal_palate_morphology | 1.21076523 |
79 | MP0005423_abnormal_somatic_nervous | 1.20991965 |
80 | * MP0005377_hearing/vestibular/ear_phenot | 1.20842701 |
81 | * MP0003878_abnormal_ear_physiology | 1.20842701 |
82 | MP0002736_abnormal_nociception_after | 1.20110541 |
83 | MP0005451_abnormal_body_composition | 1.19789876 |
84 | MP0005670_abnormal_white_adipose | 1.19699636 |
85 | MP0004742_abnormal_vestibular_system | 1.19038125 |
86 | MP0002876_abnormal_thyroid_physiology | 1.18622048 |
87 | MP0002752_abnormal_somatic_nervous | 1.18402072 |
88 | MP0005195_abnormal_posterior_eye | 1.18269889 |
89 | * MP0002152_abnormal_brain_morphology | 1.16685655 |
90 | MP0005187_abnormal_penis_morphology | 1.13275411 |
91 | * MP0001963_abnormal_hearing_physiology | 1.12143664 |
92 | MP0005319_abnormal_enzyme/_coenzyme | 1.12060804 |
93 | MP0005551_abnormal_eye_electrophysiolog | 1.11154153 |
94 | MP0006276_abnormal_autonomic_nervous | 1.09940246 |
95 | MP0002111_abnormal_tail_morphology | 1.07973981 |
96 | MP0005395_other_phenotype | 1.04894758 |
97 | MP0005666_abnormal_adipose_tissue | 1.03495099 |
98 | MP0002734_abnormal_mechanical_nocicepti | 1.03032919 |
99 | MP0002882_abnormal_neuron_morphology | 1.02250046 |
100 | MP0000516_abnormal_urinary_system | 1.02203722 |
101 | MP0005367_renal/urinary_system_phenotyp | 1.02203722 |
102 | MP0003890_abnormal_embryonic-extraembry | 1.01478730 |
103 | MP0003935_abnormal_craniofacial_develop | 0.99573352 |
104 | MP0001661_extended_life_span | 0.99039755 |
105 | MP0001529_abnormal_vocalization | 0.99028475 |
106 | * MP0005584_abnormal_enzyme/coenzyme_acti | 0.98856255 |
107 | MP0001502_abnormal_circadian_rhythm | 0.97724045 |
108 | MP0000230_abnormal_systemic_arterial | 0.97673483 |
109 | MP0002796_impaired_skin_barrier | 0.96011832 |
110 | MP0003191_abnormal_cellular_cholesterol | 0.94159562 |
111 | MP0000537_abnormal_urethra_morphology | 0.93366482 |
112 | MP0002234_abnormal_pharynx_morphology | 0.92844264 |
113 | MP0002089_abnormal_postnatal_growth/wei | 0.92395434 |
114 | MP0001764_abnormal_homeostasis | 0.91464490 |
115 | MP0005646_abnormal_pituitary_gland | 0.90380221 |
116 | MP0001968_abnormal_touch/_nociception | 0.89824983 |
117 | MP0002572_abnormal_emotion/affect_behav | 0.89165782 |
118 | MP0004858_abnormal_nervous_system | 0.87822895 |
119 | MP0002249_abnormal_larynx_morphology | 0.87598100 |
120 | MP0002063_abnormal_learning/memory/cond | 0.86969662 |
121 | MP0002909_abnormal_adrenal_gland | 0.86018721 |
122 | MP0003632_abnormal_nervous_system | 0.85846540 |
123 | MP0002932_abnormal_joint_morphology | 0.85635134 |
124 | MP0005197_abnormal_uvea_morphology | 0.85480069 |
125 | MP0000579_abnormal_nail_morphology | 0.85120343 |
126 | MP0000427_abnormal_hair_cycle | 0.83357497 |
127 | * MP0002116_abnormal_craniofacial_bone | 0.83293362 |
128 | MP0003635_abnormal_synaptic_transmissio | 0.83215960 |
129 | MP0000534_abnormal_ureter_morphology | 0.83028012 |
130 | MP0006036_abnormal_mitochondrial_physio | 0.82501257 |
131 | MP0001666_abnormal_nutrient_absorption | 0.82248807 |
132 | MP0004142_abnormal_muscle_tone | 0.81328461 |
133 | MP0003315_abnormal_perineum_morphology | 0.81164799 |
134 | MP0009672_abnormal_birth_weight | 0.80345629 |
135 | MP0000569_abnormal_digit_pigmentation | 0.80192587 |
136 | MP0004782_abnormal_surfactant_physiolog | 0.79838445 |
137 | MP0002098_abnormal_vibrissa_morphology | 0.77000307 |
138 | MP0003705_abnormal_hypodermis_morpholog | 0.76666702 |
139 | MP0005501_abnormal_skin_physiology | 0.76139348 |
140 | * MP0002896_abnormal_bone_mineralization | 0.75157333 |
141 | MP0004133_heterotaxia | 0.70025118 |
142 | MP0003566_abnormal_cell_adhesion | 0.69967827 |
143 | MP0000371_diluted_coat_color | 0.68861154 |
144 | MP0002118_abnormal_lipid_homeostasis | 0.67426345 |
145 | MP0009053_abnormal_anal_canal | 0.64103885 |
146 | MP0005220_abnormal_exocrine_pancreas | 0.63461355 |
147 | MP0004147_increased_porphyrin_level | 0.60165487 |
148 | MP0002084_abnormal_developmental_patter | 0.58790956 |
149 | MP0010329_abnormal_lipoprotein_level | 0.58544292 |
150 | * MP0009642_abnormal_blood_homeostasis | 0.57958853 |
151 | MP0003172_abnormal_lysosome_physiology | 0.55757040 |
152 | MP0005535_abnormal_body_temperature | 0.55386094 |
153 | MP0002115_abnormal_skeleton_extremities | 0.54522411 |
154 | MP0009703_decreased_birth_body | 0.54375096 |
155 | MP0000598_abnormal_liver_morphology | 0.54122140 |
156 | MP0005408_hypopigmentation | 0.53951056 |
157 | MP0000678_abnormal_parathyroid_gland | 0.53751900 |
158 | MP0001730_embryonic_growth_arrest | 0.50278434 |
159 | MP0004957_abnormal_blastocyst_morpholog | 0.48637685 |
160 | MP0003646_muscle_fatigue | 0.48229880 |
161 | MP0001485_abnormal_pinna_reflex | 0.47592276 |
162 | MP0003959_abnormal_lean_body | 0.45547110 |
163 | MP0003795_abnormal_bone_structure | 0.45444755 |
164 | MP0000609_abnormal_liver_physiology | 0.45369586 |
165 | MP0001915_intracranial_hemorrhage | 0.45072578 |
166 | MP0003942_abnormal_urinary_system | 0.44841769 |
167 | MP0002086_abnormal_extraembryonic_tissu | 0.44536914 |
168 | MP0000747_muscle_weakness | 0.44486942 |
169 | MP0003984_embryonic_growth_retardation | 0.43376239 |
170 | MP0002088_abnormal_embryonic_growth/wei | 0.43200942 |
171 | MP0004233_abnormal_muscle_weight | 0.42905971 |
172 | MP0003786_premature_aging | 0.41167003 |
173 | MP0005375_adipose_tissue_phenotype | 0.40323953 |
174 | MP0000163_abnormal_cartilage_morphology | 0.39818141 |
175 | MP0001672_abnormal_embryogenesis/_devel | 0.39376007 |
176 | MP0005380_embryogenesis_phenotype | 0.39376007 |
177 | MP0003221_abnormal_cardiomyocyte_apopto | 0.38961224 |
178 | * MP0002697_abnormal_eye_size | 0.37776307 |
179 | * MP0001697_abnormal_embryo_size | 0.36989820 |
180 | MP0000377_abnormal_hair_follicle | 0.36452487 |
181 | MP0003115_abnormal_respiratory_system | 0.36309131 |
182 | MP0003119_abnormal_digestive_system | 0.36194581 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased circulating renin level (HP:0000848) | 8.36222520 |
2 | Hypokalemic alkalosis (HP:0001949) | 7.58493581 |
3 | Hyperactive renin-angiotensin system (HP:0000841) | 7.45289630 |
4 | Hypomagnesemia (HP:0002917) | 7.43822792 |
5 | Metabolic alkalosis (HP:0200114) | 7.39273476 |
6 | Polyuria (HP:0000103) | 6.84379027 |
7 | Gout (HP:0001997) | 6.81428922 |
8 | Abnormality of chloride homeostasis (HP:0011422) | 6.51802386 |
9 | Abnormal urine output (HP:0012590) | 6.44131325 |
10 | Abnormality of magnesium homeostasis (HP:0004921) | 6.26685494 |
11 | Abnormality of renal excretion (HP:0011036) | 6.14989868 |
12 | Abnormal drinking behavior (HP:0030082) | 5.55573137 |
13 | Polydipsia (HP:0001959) | 5.55573137 |
14 | Tetany (HP:0001281) | 5.42647791 |
15 | Renal salt wasting (HP:0000127) | 5.23237417 |
16 | Abnormality of renin-angiotensin system (HP:0000847) | 5.01659597 |
17 | Hyperuricemia (HP:0002149) | 4.98829739 |
18 | Increased purine levels (HP:0004368) | 4.98829739 |
19 | Hyperaldosteronism (HP:0000859) | 4.90354779 |
20 | Hyperglycinuria (HP:0003108) | 4.71418187 |
21 | Alkalosis (HP:0001948) | 4.68487478 |
22 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.64069304 |
23 | Hypercalciuria (HP:0002150) | 4.25052074 |
24 | Abnormality of purine metabolism (HP:0004352) | 4.18454808 |
25 | Vitreoretinal degeneration (HP:0000655) | 4.13429668 |
26 | * Proximal tubulopathy (HP:0000114) | 3.88317397 |
27 | Hypokalemia (HP:0002900) | 3.81627315 |
28 | Abnormality of glycine metabolism (HP:0010895) | 3.81203780 |
29 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.81203780 |
30 | Renal tubular acidosis (HP:0001947) | 3.53898460 |
31 | Generalized aminoaciduria (HP:0002909) | 3.52019630 |
32 | Abnormality of the ischium (HP:0003174) | 3.47964675 |
33 | Anophthalmia (HP:0000528) | 3.43660102 |
34 | Glycosuria (HP:0003076) | 3.41998394 |
35 | Abnormality of urine glucose concentration (HP:0011016) | 3.41998394 |
36 | Cutaneous finger syndactyly (HP:0010554) | 3.20946689 |
37 | Delayed epiphyseal ossification (HP:0002663) | 3.18971426 |
38 | Morphological abnormality of the middle ear (HP:0008609) | 3.18736062 |
39 | Abnormality of potassium homeostasis (HP:0011042) | 3.15534802 |
40 | Abnormality of nucleobase metabolism (HP:0010932) | 3.14793677 |
41 | Ketoacidosis (HP:0001993) | 3.12491280 |
42 | Nephrocalcinosis (HP:0000121) | 3.07385734 |
43 | Hydroxyprolinuria (HP:0003080) | 3.02731994 |
44 | Abnormality of proline metabolism (HP:0010907) | 3.02731994 |
45 | Hyperphosphaturia (HP:0003109) | 3.00965522 |
46 | Neonatal short-limb short stature (HP:0008921) | 2.89563485 |
47 | Abnormal urine phosphate concentration (HP:0012599) | 2.88734475 |
48 | Hypoplastic ischia (HP:0003175) | 2.88607519 |
49 | Confusion (HP:0001289) | 2.85836356 |
50 | Cutaneous syndactyly (HP:0012725) | 2.78896737 |
51 | Metaphyseal cupping (HP:0003021) | 2.74194468 |
52 | Septo-optic dysplasia (HP:0100842) | 2.73678466 |
53 | Bifid tongue (HP:0010297) | 2.73537447 |
54 | Nephrolithiasis (HP:0000787) | 2.70426265 |
55 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.68712256 |
56 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.62645341 |
57 | Hyperglycinemia (HP:0002154) | 2.60818564 |
58 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.60475614 |
59 | Widely patent fontanelles and sutures (HP:0004492) | 2.59796799 |
60 | Tubulointerstitial fibrosis (HP:0005576) | 2.59638461 |
61 | Renal hypoplasia (HP:0000089) | 2.58827148 |
62 | Ketosis (HP:0001946) | 2.57279741 |
63 | Potter facies (HP:0002009) | 2.56449870 |
64 | Facial shape deformation (HP:0011334) | 2.56449870 |
65 | Tubular atrophy (HP:0000092) | 2.55735804 |
66 | Hypoplastic pelvis (HP:0008839) | 2.54148171 |
67 | Abnormality of sodium homeostasis (HP:0010931) | 2.51740883 |
68 | Vascular calcification (HP:0004934) | 2.50684342 |
69 | Hyponatremia (HP:0002902) | 2.50168596 |
70 | Dehydration (HP:0001944) | 2.48807465 |
71 | Rickets (HP:0002748) | 2.47466749 |
72 | Enlarged kidneys (HP:0000105) | 2.47455676 |
73 | Bilateral microphthalmos (HP:0007633) | 2.45215225 |
74 | Esophageal atresia (HP:0002032) | 2.44091851 |
75 | Delayed CNS myelination (HP:0002188) | 2.43871059 |
76 | Hypophosphatemia (HP:0002148) | 2.41752286 |
77 | Broad thumb (HP:0011304) | 2.39048688 |
78 | Myelomeningocele (HP:0002475) | 2.38964213 |
79 | Hypoplasia of the ulna (HP:0003022) | 2.33523259 |
80 | Vaginal atresia (HP:0000148) | 2.33148331 |
81 | Renal dysplasia (HP:0000110) | 2.28837646 |
82 | Short 4th metacarpal (HP:0010044) | 2.28270990 |
83 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.28270990 |
84 | Vacuolated lymphocytes (HP:0001922) | 2.26116261 |
85 | Chondrocalcinosis (HP:0000934) | 2.26072116 |
86 | Genital tract atresia (HP:0001827) | 2.26021865 |
87 | Thyroid-stimulating hormone excess (HP:0002925) | 2.25467598 |
88 | Cardiovascular calcification (HP:0011915) | 2.24927317 |
89 | Abnormality of the pubic bones (HP:0003172) | 2.23934921 |
90 | Hepatoblastoma (HP:0002884) | 2.22283493 |
91 | Thin bony cortex (HP:0002753) | 2.22019609 |
92 | Chronic hepatic failure (HP:0100626) | 2.17470065 |
93 | Synostosis of carpal bones (HP:0005048) | 2.17223867 |
94 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.17006756 |
95 | Abnormality of cochlea (HP:0000375) | 2.15006236 |
96 | Malnutrition (HP:0004395) | 2.13163710 |
97 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.13142165 |
98 | Abnormality of Sharpey fibers (HP:0100685) | 2.11033539 |
99 | Irregular epiphyses (HP:0010582) | 2.10697085 |
100 | Morphological abnormality of the inner ear (HP:0011390) | 2.09215693 |
101 | Abnormality of the renal medulla (HP:0100957) | 2.08857795 |
102 | Midline defect of the nose (HP:0004122) | 2.08200419 |
103 | Partial duplication of thumb phalanx (HP:0009944) | 2.07583650 |
104 | Pancreatic cysts (HP:0001737) | 2.07393399 |
105 | Adrenal overactivity (HP:0002717) | 2.06926927 |
106 | Hyperammonemia (HP:0001987) | 2.06327674 |
107 | Preaxial foot polydactyly (HP:0001841) | 2.06262229 |
108 | Hemivertebrae (HP:0002937) | 2.05710861 |
109 | Renal tubular dysfunction (HP:0000124) | 2.04680017 |
110 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.04009541 |
111 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.03788407 |
112 | Abnormality of the diencephalon (HP:0010662) | 2.03442942 |
113 | Glomerulosclerosis (HP:0000096) | 2.02876968 |
114 | Choanal stenosis (HP:0000452) | 2.02398536 |
115 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.01852265 |
116 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.01768998 |
117 | Intestinal atresia (HP:0011100) | 2.01325830 |
118 | Trigonocephaly (HP:0000243) | 2.01184869 |
119 | Abnormality of the aortic arch (HP:0012303) | 2.00227184 |
120 | Abnormality of renal resorption (HP:0011038) | 1.98450239 |
121 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.97552764 |
122 | Dicarboxylic aciduria (HP:0003215) | 1.97552764 |
123 | Rib fusion (HP:0000902) | 1.96814640 |
124 | Nephronophthisis (HP:0000090) | 1.96536736 |
125 | Absent eyebrow (HP:0002223) | 1.96149752 |
126 | Chorioretinal atrophy (HP:0000533) | 1.96148465 |
127 | Broad phalanges of the hand (HP:0009768) | 1.95547130 |
128 | Broad long bones (HP:0005622) | 1.95277477 |
129 | Megaloblastic anemia (HP:0001889) | 1.95136805 |
130 | Hypotension (HP:0002615) | 1.93620156 |
131 | Vomiting (HP:0002013) | 1.93482445 |
132 | Oligodactyly (hands) (HP:0001180) | 1.93154588 |
133 | Oligodactyly (HP:0012165) | 1.92863173 |
134 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.92302827 |
135 | Optic nerve hypoplasia (HP:0000609) | 1.91462387 |
136 | Abnormality of the 4th metacarpal (HP:0010012) | 1.90513393 |
137 | Broad phalanx (HP:0006009) | 1.89705076 |
138 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.89569909 |
139 | Cerebellar dysplasia (HP:0007033) | 1.88732003 |
140 | Gastrointestinal atresia (HP:0002589) | 1.88544092 |
141 | Arthropathy (HP:0003040) | 1.87746956 |
142 | Broad finger (HP:0001500) | 1.87613990 |
143 | True hermaphroditism (HP:0010459) | 1.86488874 |
144 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.84998613 |
145 | Molar tooth sign on MRI (HP:0002419) | 1.84503687 |
146 | Abnormality of midbrain morphology (HP:0002418) | 1.84503687 |
147 | Metabolic acidosis (HP:0001942) | 1.82613265 |
148 | * High anterior hairline (HP:0009890) | 1.81324535 |
149 | Tachypnea (HP:0002789) | 1.80623809 |
150 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.80467637 |
151 | Aplasia of the phalanges of the hand (HP:0009802) | 1.80467637 |
152 | Aplasia involving bones of the extremities (HP:0009825) | 1.80467637 |
153 | Pancreatic fibrosis (HP:0100732) | 1.79588241 |
154 | Mixed hearing impairment (HP:0000410) | 1.79237067 |
155 | Generalized muscle weakness (HP:0003324) | 1.77066392 |
156 | Abnormal tarsal ossification (HP:0008369) | 1.76436958 |
157 | Abnormality of vitamin B metabolism (HP:0004340) | 1.75952498 |
158 | Vertebral clefting (HP:0008428) | 1.75890492 |
159 | Preaxial hand polydactyly (HP:0001177) | 1.75595543 |
160 | Missing ribs (HP:0000921) | 1.75479081 |
161 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.75061469 |
162 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.71865185 |
163 | Split foot (HP:0001839) | 1.71807748 |
164 | Absent septum pellucidum (HP:0001331) | 1.71465456 |
165 | Lethargy (HP:0001254) | 1.71442259 |
166 | Abnormality of the costochondral junction (HP:0000919) | 1.70617274 |
167 | Postaxial hand polydactyly (HP:0001162) | 1.70473930 |
168 | Lymphangioma (HP:0100764) | 1.70208769 |
169 | Coronal craniosynostosis (HP:0004440) | 1.69935197 |
170 | Tubulointerstitial abnormality (HP:0001969) | 1.69890414 |
171 | Abnormal lung lobation (HP:0002101) | 1.69641727 |
172 | Fibular hypoplasia (HP:0003038) | 1.68944262 |
173 | Pendular nystagmus (HP:0012043) | 1.68705350 |
174 | Metaphyseal irregularity (HP:0003025) | 1.68579325 |
175 | Nausea (HP:0002018) | 1.68566847 |
176 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.68187736 |
177 | Methylmalonic aciduria (HP:0012120) | 1.67631069 |
178 | Stenosis of the external auditory canal (HP:0000402) | 1.66681460 |
179 | Megalencephaly (HP:0001355) | 1.66484687 |
180 | Abnormality of carpal bone ossification (HP:0006257) | 1.65326078 |
181 | Sclerocornea (HP:0000647) | 1.65239652 |
182 | Colon cancer (HP:0003003) | 1.65172177 |
183 | Cupped ear (HP:0000378) | 1.64975014 |
184 | Wide cranial sutures (HP:0010537) | 1.57353532 |
185 | Metaphyseal dysplasia (HP:0100255) | 1.55860813 |
186 | Neonatal death (HP:0003811) | 1.54154606 |
187 | Abnormality of serum amino acid levels (HP:0003112) | 1.53871172 |
188 | Abnormality of the renal cortex (HP:0011035) | 1.53712060 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK3 | 8.75975734 |
2 | WNK4 | 8.00654528 |
3 | OXSR1 | 7.32097118 |
4 | STK39 | 3.88003409 |
5 | TNIK | 3.86247151 |
6 | EPHA4 | 3.25770735 |
7 | STK38L | 2.86773184 |
8 | CASK | 2.32758530 |
9 | NEK1 | 2.22477354 |
10 | EPHA2 | 2.14654835 |
11 | BCR | 2.12854193 |
12 | MAP3K4 | 2.11066655 |
13 | BCKDK | 2.09553697 |
14 | NTRK2 | 2.05105271 |
15 | MKNK1 | 1.90974646 |
16 | PDK4 | 1.90450807 |
17 | PDK3 | 1.90450807 |
18 | MARK1 | 1.79333933 |
19 | MAP2K7 | 1.71317232 |
20 | MKNK2 | 1.69292748 |
21 | SGK494 | 1.67237523 |
22 | SGK223 | 1.67237523 |
23 | MST4 | 1.59190528 |
24 | NTRK1 | 1.52236596 |
25 | TYRO3 | 1.50948151 |
26 | PDK2 | 1.49464034 |
27 | PLK2 | 1.46797479 |
28 | WNK1 | 1.44460465 |
29 | PLK4 | 1.31372313 |
30 | SRPK1 | 1.31182016 |
31 | BMPR1B | 1.20659442 |
32 | STK38 | 1.20178431 |
33 | LRRK2 | 1.10072701 |
34 | MST1R | 1.07479794 |
35 | SGK2 | 1.05712846 |
36 | SGK3 | 1.02652511 |
37 | CDK19 | 1.01423070 |
38 | PRKCG | 1.00310667 |
39 | PIK3CA | 1.00080377 |
40 | MAPK15 | 0.93785533 |
41 | NME1 | 0.93738055 |
42 | PAK4 | 0.93593352 |
43 | CDC7 | 0.90120069 |
44 | SCYL2 | 0.89238172 |
45 | CDK12 | 0.89227771 |
46 | MAP3K3 | 0.88898037 |
47 | TRIM28 | 0.88579912 |
48 | DYRK2 | 0.87900368 |
49 | NTRK3 | 0.84879782 |
50 | PNCK | 0.82623317 |
51 | TIE1 | 0.81624916 |
52 | LATS1 | 0.80463485 |
53 | CSNK1G2 | 0.79743967 |
54 | PRKCI | 0.78926594 |
55 | RPS6KA4 | 0.77924818 |
56 | UHMK1 | 0.77573388 |
57 | MAP3K10 | 0.77354131 |
58 | FGFR4 | 0.77325064 |
59 | PTK2 | 0.76677216 |
60 | MET | 0.74975845 |
61 | TTK | 0.74633466 |
62 | GSK3A | 0.74429889 |
63 | STK10 | 0.69784743 |
64 | MAP3K9 | 0.68614708 |
65 | FER | 0.62062419 |
66 | WEE1 | 0.61208145 |
67 | PLK1 | 0.59277166 |
68 | MAP2K4 | 0.58657462 |
69 | NLK | 0.57831533 |
70 | PRKCE | 0.57627739 |
71 | BRSK2 | 0.56211935 |
72 | ROCK2 | 0.55350557 |
73 | PTK6 | 0.54159766 |
74 | GRK6 | 0.50434660 |
75 | PASK | 0.49630413 |
76 | CDK5 | 0.49045707 |
77 | CSNK1G1 | 0.48833132 |
78 | ERBB3 | 0.48457109 |
79 | DYRK1A | 0.48329294 |
80 | SGK1 | 0.47987077 |
81 | PAK6 | 0.46711121 |
82 | RIPK1 | 0.46442306 |
83 | PKN1 | 0.45073337 |
84 | AKT2 | 0.42473049 |
85 | MINK1 | 0.41867059 |
86 | FRK | 0.41642747 |
87 | GRK1 | 0.41132024 |
88 | KSR1 | 0.40228472 |
89 | EPHB2 | 0.39629445 |
90 | MUSK | 0.39099082 |
91 | PRKAA1 | 0.39022791 |
92 | CSNK1A1 | 0.38237901 |
93 | MTOR | 0.37700015 |
94 | PINK1 | 0.37627077 |
95 | CDK18 | 0.37438584 |
96 | PKN2 | 0.37416251 |
97 | ATR | 0.37155873 |
98 | MAP4K2 | 0.36662026 |
99 | TSSK6 | 0.35398092 |
100 | EPHB1 | 0.35359515 |
101 | ATM | 0.35225871 |
102 | CSNK1A1L | 0.35087119 |
103 | CDK11A | 0.34859575 |
104 | CDK15 | 0.34105885 |
105 | PIM1 | 0.34024082 |
106 | CSNK1D | 0.33686530 |
107 | EPHA3 | 0.33522815 |
108 | PAK3 | 0.32263879 |
109 | MAP3K8 | 0.32007967 |
110 | TGFBR2 | 0.31118196 |
111 | PRKACB | 0.31095624 |
112 | TAF1 | 0.30716296 |
113 | CDK3 | 0.30474117 |
114 | CAMK2A | 0.30220859 |
115 | INSRR | 0.28739817 |
116 | RPS6KB2 | 0.28379685 |
117 | BUB1 | 0.27193987 |
118 | MAP3K7 | 0.26801170 |
119 | MAP2K3 | 0.25447005 |
120 | ABL2 | 0.25431095 |
121 | DYRK1B | 0.25390071 |
122 | ZAK | 0.25279828 |
123 | ERBB4 | 0.22996900 |
124 | FGFR1 | 0.22874949 |
125 | BMX | 0.22426707 |
126 | AURKA | 0.21460105 |
127 | FGFR2 | 0.21423305 |
128 | MAP3K2 | 0.21102614 |
129 | PDPK1 | 0.20696274 |
130 | LATS2 | 0.20217131 |
131 | TTN | 0.19760407 |
132 | STK3 | 0.17749727 |
133 | NEK2 | 0.17197455 |
134 | MAP2K2 | 0.16708060 |
135 | MAPK11 | 0.16252999 |
136 | TGFBR1 | 0.16097404 |
137 | ERBB2 | 0.15766174 |
138 | PRKCZ | 0.15694376 |
139 | CDK4 | 0.15046681 |
140 | PRKCD | 0.15011046 |
141 | PRKAA2 | 0.14420872 |
142 | PDGFRA | 0.14239432 |
143 | AURKB | 0.13635094 |
144 | BRD4 | 0.13145801 |
145 | AKT3 | 0.11885673 |
146 | CSNK1E | 0.11279046 |
147 | STK11 | 0.10472400 |
148 | INSR | 0.09538101 |
149 | CAMK1D | 0.08611361 |
150 | ROCK1 | 0.07395650 |
151 | MELK | 0.07312202 |
152 | IRAK3 | 0.06978502 |
153 | KDR | 0.06968180 |
154 | NEK9 | 0.06801308 |
155 | CDK7 | 0.04568494 |
156 | CDK6 | 0.03782802 |
157 | TRIB3 | 0.03714987 |
158 | PRKCA | 0.03183178 |
159 | PRKACG | 0.03049060 |
160 | TESK1 | 0.02940642 |
161 | CAMK1G | 0.02770636 |
162 | PLK3 | 0.02382725 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 3.81436886 |
2 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.57297176 |
3 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.43278093 |
4 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 3.30633888 |
5 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.26725909 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.23606511 |
7 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 3.06075027 |
8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.98765971 |
9 | * Hedgehog signaling pathway_Homo sapiens_hsa04340 | 2.97577526 |
10 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.97438569 |
11 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.93621972 |
12 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.70534920 |
13 | Nicotine addiction_Homo sapiens_hsa05033 | 2.65493785 |
14 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.50069030 |
15 | Peroxisome_Homo sapiens_hsa04146 | 2.35322295 |
16 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.26862687 |
17 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.23131580 |
18 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.21261955 |
19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.14639706 |
20 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.09267229 |
21 | Axon guidance_Homo sapiens_hsa04360 | 2.05567831 |
22 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.87153812 |
23 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.86720938 |
24 | Carbon metabolism_Homo sapiens_hsa01200 | 1.84078953 |
25 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.79702431 |
26 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.76848108 |
27 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.72729473 |
28 | Bile secretion_Homo sapiens_hsa04976 | 1.68909993 |
29 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.63628463 |
30 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.60509173 |
31 | Lysine degradation_Homo sapiens_hsa00310 | 1.60246260 |
32 | Mineral absorption_Homo sapiens_hsa04978 | 1.59754536 |
33 | Melanogenesis_Homo sapiens_hsa04916 | 1.58359548 |
34 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.55814993 |
35 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.50307426 |
36 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.45971197 |
37 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.45760269 |
38 | Other glycan degradation_Homo sapiens_hsa00511 | 1.43752838 |
39 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.40257949 |
40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.37186948 |
41 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.37161776 |
42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.36651434 |
43 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.32532988 |
44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.28759009 |
45 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.25473497 |
46 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.24025229 |
47 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.23825511 |
48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.20029228 |
49 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.19949245 |
50 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.17978258 |
51 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.09970740 |
52 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.07841513 |
53 | Homologous recombination_Homo sapiens_hsa03440 | 1.07558247 |
54 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.06907370 |
55 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.05661997 |
56 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.05613637 |
57 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.04673723 |
58 | Phototransduction_Homo sapiens_hsa04744 | 1.04419286 |
59 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.03410054 |
60 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.02213597 |
61 | Circadian entrainment_Homo sapiens_hsa04713 | 1.02186709 |
62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.01162184 |
63 | Taste transduction_Homo sapiens_hsa04742 | 0.98638125 |
64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.97980598 |
65 | Morphine addiction_Homo sapiens_hsa05032 | 0.96575082 |
66 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.95877025 |
67 | RNA degradation_Homo sapiens_hsa03018 | 0.95868744 |
68 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.94373871 |
69 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.92891312 |
70 | GABAergic synapse_Homo sapiens_hsa04727 | 0.90808766 |
71 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.90236955 |
72 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.85812281 |
73 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.85570362 |
74 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.85131757 |
75 | Cocaine addiction_Homo sapiens_hsa05030 | 0.83665589 |
76 | Ribosome_Homo sapiens_hsa03010 | 0.83257444 |
77 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.82290279 |
78 | Histidine metabolism_Homo sapiens_hsa00340 | 0.81846247 |
79 | Basal transcription factors_Homo sapiens_hsa03022 | 0.81060887 |
80 | Lysosome_Homo sapiens_hsa04142 | 0.80975789 |
81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.78224379 |
82 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.75645404 |
83 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.75531091 |
84 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.75471167 |
85 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.74785374 |
86 | Spliceosome_Homo sapiens_hsa03040 | 0.74434245 |
87 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.73793129 |
88 | Pathways in cancer_Homo sapiens_hsa05200 | 0.68052034 |
89 | RNA transport_Homo sapiens_hsa03013 | 0.67729781 |
90 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.66210866 |
91 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.65873831 |
92 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.64921819 |
93 | Mismatch repair_Homo sapiens_hsa03430 | 0.63469707 |
94 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.63275643 |
95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.60498348 |
96 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59020697 |
97 | Cell cycle_Homo sapiens_hsa04110 | 0.58376138 |
98 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.57896513 |
99 | Protein export_Homo sapiens_hsa03060 | 0.57635021 |
100 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56883410 |
101 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.56084976 |
102 | Insulin secretion_Homo sapiens_hsa04911 | 0.55346721 |
103 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.54493436 |
104 | Colorectal cancer_Homo sapiens_hsa05210 | 0.54467750 |
105 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51314384 |
106 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.49546834 |
107 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.49090244 |
108 | Gap junction_Homo sapiens_hsa04540 | 0.49044996 |
109 | Circadian rhythm_Homo sapiens_hsa04710 | 0.47992600 |
110 | Endometrial cancer_Homo sapiens_hsa05213 | 0.47116932 |
111 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.46960082 |
112 | Alcoholism_Homo sapiens_hsa05034 | 0.46368630 |
113 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.45902520 |
114 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.45886739 |
115 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.45287088 |
116 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45009668 |
117 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43904726 |
118 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.43770081 |
119 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.42954489 |
120 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.42937076 |
121 | Tight junction_Homo sapiens_hsa04530 | 0.42379232 |
122 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.41821810 |
123 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.41462290 |
124 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.40628319 |
125 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.40200154 |
126 | ABC transporters_Homo sapiens_hsa02010 | 0.38449981 |
127 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.37438040 |
128 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35261598 |
129 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.34641545 |
130 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33878019 |
131 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.30951203 |
132 | Retinol metabolism_Homo sapiens_hsa00830 | 0.30707998 |
133 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.30494930 |
134 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.28543138 |
135 | Bladder cancer_Homo sapiens_hsa05219 | 0.27082585 |
136 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.26792214 |
137 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.26168491 |
138 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.20935298 |
139 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.20860204 |
140 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.18561652 |
141 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.18524594 |
142 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.18297727 |
143 | Galactose metabolism_Homo sapiens_hsa00052 | 0.18186548 |
144 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.16316935 |
145 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.15937149 |
146 | * Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.15574234 |
147 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.13391854 |
148 | Adherens junction_Homo sapiens_hsa04520 | 0.11589327 |
149 | Insulin resistance_Homo sapiens_hsa04931 | 0.10844928 |
150 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.10838577 |
151 | Sulfur relay system_Homo sapiens_hsa04122 | 0.10369628 |
152 | Focal adhesion_Homo sapiens_hsa04510 | 0.08489006 |
153 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.08114598 |
154 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.06832627 |
155 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | -0.0715990 |
156 | Amoebiasis_Homo sapiens_hsa05146 | -0.0580717 |
157 | Hepatitis C_Homo sapiens_hsa05160 | -0.0376830 |
158 | FoxO signaling pathway_Homo sapiens_hsa04068 | -0.0259005 |
159 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | -0.0239452 |
160 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | -0.0035779 |