LRRC10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)9.53642113
2cardiac myofibril assembly (GO:0055003)9.29335465
3myofibril assembly (GO:0030239)8.04836275
4negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.78089732
5cardiac muscle contraction (GO:0060048)7.16995912
6negative regulation of potassium ion transmembrane transport (GO:1901380)7.11097859
7regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.86059321
8cardiac chamber formation (GO:0003207)6.85101848
9muscle filament sliding (GO:0030049)6.68171403
10actin-myosin filament sliding (GO:0033275)6.68171403
11tricarboxylic acid cycle (GO:0006099)6.58953156
12positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.50318057
13regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.41485557
14regulation of actin filament-based movement (GO:1903115)6.35124550
15* cardiac muscle cell development (GO:0055013)6.28678139
16cardiac muscle tissue morphogenesis (GO:0055008)6.25335128
17ventricular cardiac muscle tissue morphogenesis (GO:0055010)6.22495490
18regulation of relaxation of muscle (GO:1901077)6.21933600
19adult heart development (GO:0007512)6.08704636
20bundle of His cell to Purkinje myocyte communication (GO:0086069)6.07232810
21regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)6.04552443
22actomyosin structure organization (GO:0031032)5.96476894
23ventricular cardiac muscle cell action potential (GO:0086005)5.95560985
24cardiac ventricle formation (GO:0003211)5.90898601
25* cardiac cell development (GO:0055006)5.89698446
26cardiac muscle hypertrophy (GO:0003300)5.87145541
27plasma membrane repair (GO:0001778)5.70569243
28muscle tissue morphogenesis (GO:0060415)5.55031813
29actin-mediated cell contraction (GO:0070252)5.54049430
30striated muscle hypertrophy (GO:0014897)5.53882663
31heart trabecula formation (GO:0060347)5.51303724
32regulation of sarcomere organization (GO:0060297)5.50106435
33regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.48167850
34heart contraction (GO:0060047)5.46037136
35heart process (GO:0003015)5.46037136
36striated muscle contraction (GO:0006941)5.25375382
37regulation of the force of heart contraction (GO:0002026)5.22834431
38regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.19006797
39regulation of skeletal muscle contraction (GO:0014819)5.18665210
40mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.11365419
41regulation of striated muscle contraction (GO:0006942)5.08518663
42atrial septum morphogenesis (GO:0060413)4.92471607
43cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.92304342
44carnitine shuttle (GO:0006853)4.91441498
45muscle hypertrophy (GO:0014896)4.91148324
46cell communication involved in cardiac conduction (GO:0086065)4.83685709
47regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.82699250
48regulation of cell communication by electrical coupling (GO:0010649)4.80879060
49ATP synthesis coupled proton transport (GO:0015986)4.80025341
50energy coupled proton transport, down electrochemical gradient (GO:0015985)4.80025341
51regulation of acyl-CoA biosynthetic process (GO:0050812)4.72883805
52regulation of membrane repolarization (GO:0060306)4.67990025
53mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.58991207
54negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.49163062
55membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.48766607
56regulation of cardiac muscle cell contraction (GO:0086004)4.46866839
57respiratory electron transport chain (GO:0022904)4.46507284
58sarcoplasmic reticulum calcium ion transport (GO:0070296)4.37664629
59electron transport chain (GO:0022900)4.33260251
60regulation of coenzyme metabolic process (GO:0051196)4.32550351
61regulation of cofactor metabolic process (GO:0051193)4.32550351
62regulation of cardiac muscle contraction (GO:0055117)4.32515726
63negative regulation of striated muscle cell apoptotic process (GO:0010664)4.25101424
64fatty acid transmembrane transport (GO:1902001)4.23591312
65oxidative phosphorylation (GO:0006119)4.23469868
66cell communication by electrical coupling (GO:0010644)4.22179540
67response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.21502133
68regulation of heart rate (GO:0002027)4.20107591
69regulation of cardioblast differentiation (GO:0051890)4.19090279
70actin filament-based movement (GO:0030048)4.15041670
71regulation of cardiac muscle cell apoptotic process (GO:0010665)4.14378013
72cardiac muscle cell action potential involved in contraction (GO:0086002)4.14238478
73cardiac muscle hypertrophy in response to stress (GO:0014898)4.12661703
74muscle hypertrophy in response to stress (GO:0003299)4.12661703
75cardiac muscle adaptation (GO:0014887)4.12661703
76regulation of ATP catabolic process (GO:1903289)4.10264628
77regulation of ATPase activity (GO:0043462)4.10264628
78cardiac muscle cell action potential (GO:0086001)4.10089080
79cardiac right ventricle morphogenesis (GO:0003215)4.07937642
80NADH metabolic process (GO:0006734)4.00332814
81cardiac muscle tissue development (GO:0048738)3.98909972
82ventricular cardiac muscle cell development (GO:0055015)3.98122995
83relaxation of cardiac muscle (GO:0055119)3.97822668
84negative regulation of protein localization to cell surface (GO:2000009)3.93691568
85negative regulation of potassium ion transport (GO:0043267)3.92193495
86regulation of heart contraction (GO:0008016)3.91658413
87positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.88669693
88oxygen transport (GO:0015671)3.83804897
892-oxoglutarate metabolic process (GO:0006103)3.81544402
90adrenergic receptor signaling pathway (GO:0071875)3.80056030
91positive regulation of ATP catabolic process (GO:1903291)3.78627433
92positive regulation of ATPase activity (GO:0032781)3.78627433
93positive regulation of cardiac muscle cell differentiation (GO:2000727)3.78477538
94regulation of sequestering of triglyceride (GO:0010889)3.69845599
95cardiac conduction (GO:0061337)3.69537392
96positive regulation of heart rate (GO:0010460)3.65880399
97carnitine transmembrane transport (GO:1902603)3.61567077
98regulation of heart rate by cardiac conduction (GO:0086091)3.59124299
99positive regulation of heart contraction (GO:0045823)3.59040205
100creatine metabolic process (GO:0006600)3.58239852
101trabecula formation (GO:0060343)3.51514526
102regulation of sulfur metabolic process (GO:0042762)3.49536145
103positive regulation of cation channel activity (GO:2001259)3.45241075
104negative regulation of cytosolic calcium ion concentration (GO:0051481)3.44190327
105regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.42545155
106ventricular trabecula myocardium morphogenesis (GO:0003222)3.38818203
107regulation of striated muscle cell apoptotic process (GO:0010662)3.38125360
108* striated muscle cell development (GO:0055002)3.36542850
109regulation of muscle contraction (GO:0006937)3.36357796
110negative regulation of heart rate (GO:0010459)3.34685671
111regulation of secondary heart field cardioblast proliferation (GO:0003266)3.34079682
112regulation of cardioblast proliferation (GO:0003264)3.34079682
113response to caffeine (GO:0031000)3.33386856
114response to inactivity (GO:0014854)3.30090993
115positive regulation of cardiac muscle tissue development (GO:0055025)3.30027923
116carnitine transport (GO:0015879)3.28629415
117amino-acid betaine transport (GO:0015838)3.28629415
118positive regulation of cardiac muscle tissue growth (GO:0055023)3.28209821
119muscle contraction (GO:0006936)3.27479023
120relaxation of muscle (GO:0090075)3.25149666
121outflow tract septum morphogenesis (GO:0003148)3.21599893
122positive regulation of action potential (GO:0045760)3.19256491
123positive regulation of cardiac muscle cell proliferation (GO:0060045)3.15863899
124cardiac septum development (GO:0003279)3.14106536
125positive regulation of sodium ion transport (GO:0010765)3.03943198
126heart valve formation (GO:0003188)3.01554392
127negative regulation of calcium ion transmembrane transport (GO:1903170)2.94140896
128negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.94140896
129positive regulation of heart growth (GO:0060421)2.93347266
130regulation of cardiac muscle cell proliferation (GO:0060043)2.90874591
131multicellular organismal signaling (GO:0035637)2.90185693
132regulation of muscle system process (GO:0090257)2.87529457
133embryonic heart tube development (GO:0035050)2.84885440
134regulation of calcium ion transmembrane transporter activity (GO:1901019)2.81677110
135regulation of calcium ion transmembrane transport (GO:1903169)2.81677110

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.14148188
2* EP300_21415370_ChIP-Seq_HL-1_Mouse5.27618505
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.95604536
4* TBX20_22328084_ChIP-Seq_HEART_Mouse4.31794138
5* TBX20_22080862_ChIP-Seq_HEART_Mouse4.31794138
6RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.10022696
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.02581514
8MEF2A_21415370_ChIP-Seq_HL-1_Mouse3.32577455
9VDR_22108803_ChIP-Seq_LS180_Human3.32346145
10GBX2_23144817_ChIP-Seq_PC3_Human3.31321397
11ZNF263_19887448_ChIP-Seq_K562_Human3.19478831
12ESR1_20079471_ChIP-ChIP_T-47D_Human3.11339423
13CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.01305586
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.86927837
15RARG_19884340_ChIP-ChIP_MEFs_Mouse2.75841943
16* GATA4_21415370_ChIP-Seq_HL-1_Mouse2.62955706
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.48616858
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.46767970
19POU3F2_20337985_ChIP-ChIP_501MEL_Human2.41799209
20TAF15_26573619_Chip-Seq_HEK293_Human2.35769161
21EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.30293648
22EZH2_22144423_ChIP-Seq_EOC_Human2.15946250
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.15465247
24PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.10607115
25ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.10296625
26IGF1R_20145208_ChIP-Seq_DFB_Human2.05306741
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.04902024
28NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.03396434
29PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.97294541
30AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.96628833
31BP1_19119308_ChIP-ChIP_Hs578T_Human1.96096197
32SMAD4_21799915_ChIP-Seq_A2780_Human1.90777338
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.89752028
34P300_19829295_ChIP-Seq_ESCs_Human1.85084635
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.83333919
36* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.83277449
37FUS_26573619_Chip-Seq_HEK293_Human1.77874715
38PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.77442210
39PIAS1_25552417_ChIP-Seq_VCAP_Human1.70814738
40CLOCK_20551151_ChIP-Seq_293T_Human1.69009775
41EWS_26573619_Chip-Seq_HEK293_Human1.64925410
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.63272507
43NR3C1_21868756_ChIP-Seq_MCF10A_Human1.62655725
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.61200797
45ESR2_21235772_ChIP-Seq_MCF-7_Human1.60374345
46FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.59943060
47STAT3_23295773_ChIP-Seq_U87_Human1.59620828
48MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.59409146
49NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.58426377
50* TCF4_23295773_ChIP-Seq_U87_Human1.57971407
51SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.55781645
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.55205677
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.54425191
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.53270956
55TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.52780226
56TRIM28_21343339_ChIP-Seq_HEK293_Human1.51065885
57ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49594778
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.48417063
59PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.47958449
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47667605
61ER_23166858_ChIP-Seq_MCF-7_Human1.45258296
62EZH2_27304074_Chip-Seq_ESCs_Mouse1.45156560
63UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.43462112
64OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39220941
65EZH2_27294783_Chip-Seq_NPCs_Mouse1.39216543
66KDM2B_26808549_Chip-Seq_SUP-B15_Human1.38157393
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.36571776
68ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.34725347
69GATA1_22025678_ChIP-Seq_K562_Human1.34027237
70SALL1_21062744_ChIP-ChIP_HESCs_Human1.33291162
71TP53_16413492_ChIP-PET_HCT116_Human1.32611298
72TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30936435
73CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.30602661
74PPARA_22158963_ChIP-Seq_LIVER_Mouse1.29961397
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28749459
76LXR_22158963_ChIP-Seq_LIVER_Mouse1.26146651
77TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.25821340
78ISL1_27105846_Chip-Seq_CPCs_Mouse1.25615557
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25127062
80SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.24452503
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23820466
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23820466
83TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22099608
84SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22052879
85AR_25329375_ChIP-Seq_VCAP_Human1.21986141
86RUNX2_22187159_ChIP-Seq_PCA_Human1.21694135
87TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20509178
88NANOG_19829295_ChIP-Seq_ESCs_Human1.20202608
89SOX2_19829295_ChIP-Seq_ESCs_Human1.20202608
90TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19617990
91TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.19340632
92TAL1_26923725_Chip-Seq_HPCs_Mouse1.18611925
93LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17669232
94TBL1_22424771_ChIP-Seq_293T_Human1.17072668
95MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.16580882
96IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16473498
97CBP_20019798_ChIP-Seq_JUKART_Human1.16473498
98TCF4_22108803_ChIP-Seq_LS180_Human1.16317353
99KLF5_20875108_ChIP-Seq_MESCs_Mouse1.15649658
100TP63_22573176_ChIP-Seq_HFKS_Human1.15443087
101NANOG_18555785_Chip-Seq_ESCs_Mouse1.14760937
102PPAR_26484153_Chip-Seq_NCI-H1993_Human1.14714567
103NFE2_27457419_Chip-Seq_LIVER_Mouse1.14563154
104ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.14170685
105GATA2_21666600_ChIP-Seq_HMVEC_Human1.14016814
106EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.13969858
107* CRX_20693478_ChIP-Seq_RETINA_Mouse1.13657459
108KDM2B_26808549_Chip-Seq_DND41_Human1.12781569
109BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.12715405
110CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12455640
111JARID2_20064375_ChIP-Seq_MESCs_Mouse1.12287713
112* CTCF_27219007_Chip-Seq_Bcells_Human1.11332279
113TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10729356
114E2F1_18555785_Chip-Seq_ESCs_Mouse1.10297297
115SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.09823368
116DROSHA_22980978_ChIP-Seq_HELA_Human1.08595365
117STAT3_1855785_ChIP-Seq_MESCs_Mouse1.07774505
118PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.07538352
119SOX2_21211035_ChIP-Seq_LN229_Gbm1.07233768
120* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06999952
121RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.06991421
122EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06579849
123NR3C1_23031785_ChIP-Seq_PC12_Mouse1.05219845
124* FLI1_21867929_ChIP-Seq_TH2_Mouse1.04633544
125BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04535213
126RNF2_27304074_Chip-Seq_NSC_Mouse1.04227081
127SMAD4_21741376_ChIP-Seq_EPCs_Human1.03957514
128POU5F1_16153702_ChIP-ChIP_HESCs_Human1.03820867
129ELK3_25401928_ChIP-Seq_HUVEC_Human1.02474595
130TP53_22573176_ChIP-Seq_HFKS_Human1.01722799
131BMI1_23680149_ChIP-Seq_NPCS_Mouse1.01306604
132LXR_22292898_ChIP-Seq_THP-1_Human1.00196796
133SPI1_20517297_ChIP-Seq_HL60_Human0.99504192
134PRDM14_20953172_ChIP-Seq_ESCs_Human0.99410563
135REST_21632747_ChIP-Seq_MESCs_Mouse0.99399524
136CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99333294
137P53_22387025_ChIP-Seq_ESCs_Mouse0.98919223
138* GATA1_19941826_ChIP-Seq_K562_Human0.98857210
139RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.98844908
140SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97617297
141* EZH2_27294783_Chip-Seq_ESCs_Mouse0.97531423
142EED_16625203_ChIP-ChIP_MESCs_Mouse0.96486062
143RUNX1_27514584_Chip-Seq_MCF-7_Human0.96397276
144ATF3_27146783_Chip-Seq_COLON_Human0.95975972
145SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.95553535
146RXR_22158963_ChIP-Seq_LIVER_Mouse0.95170376
147RACK7_27058665_Chip-Seq_MCF-7_Human0.93802081
148CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92065524
149HIF1A_21447827_ChIP-Seq_MCF-7_Human0.90035242
150SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88995043
151P68_20966046_ChIP-Seq_HELA_Human0.88176425
152TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.87426723
153* SMC3_22415368_ChIP-Seq_MEFs_Mouse0.87424179
154FOXA2_19822575_ChIP-Seq_HepG2_Human0.87314409
155SMAD3_21741376_ChIP-Seq_HESCs_Human0.87178766
156AUTS2_25519132_ChIP-Seq_293T-REX_Human0.86457065
157GATA1_19941827_ChIP-Seq_MEL_Mouse0.84959831
158ZFP281_18757296_ChIP-ChIP_E14_Mouse0.84652859
159EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.84319864
160KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.84008980
161SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.82709257
162OCT4_20526341_ChIP-Seq_ESCs_Human0.82695393
163ZNF274_21170338_ChIP-Seq_K562_Hela0.82122882
164LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.81793453
165GATA1_19941827_ChIP-Seq_MEL86_Mouse0.81454985
166GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.79458283
167TP53_23651856_ChIP-Seq_MEFs_Mouse0.79296967
168DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.79242440
169* GATA2_19941826_ChIP-Seq_K562_Human0.78481913
170GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77300400
171ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.77108855
172SPI1_23127762_ChIP-Seq_K562_Human0.76545808
173BCOR_27268052_Chip-Seq_Bcells_Human0.76266009
174SMAD4_21741376_ChIP-Seq_HESCs_Human0.75577216
175WT1_25993318_ChIP-Seq_PODOCYTE_Human0.75349118
176UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.75149817
177BCL6_27268052_Chip-Seq_Bcells_Human0.75054999
178SRF_21415370_ChIP-Seq_HL-1_Mouse0.74232699
179ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.73920295
180* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.72944862
181DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.72284956
182FOXH1_21741376_ChIP-Seq_ESCs_Human0.72191334
183MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.72017017
184NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.71825229
185BCAT_22108803_ChIP-Seq_LS180_Human0.71626820

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis7.21920229
2MP0004084_abnormal_cardiac_muscle6.19322508
3MP0003646_muscle_fatigue5.55265990
4MP0000751_myopathy5.00532580
5MP0004215_abnormal_myocardial_fiber4.97612544
6MP0004036_abnormal_muscle_relaxation4.33381653
7MP0005330_cardiomyopathy4.08197341
8MP0000749_muscle_degeneration3.72771609
9MP0002972_abnormal_cardiac_muscle3.35087754
10MP0008775_abnormal_heart_ventricle3.14532925
11MP0003137_abnormal_impulse_conducting3.08564401
12MP0004087_abnormal_muscle_fiber3.03960151
13MP0001544_abnormal_cardiovascular_syste2.79605304
14MP0005385_cardiovascular_system_phenoty2.79605304
15MP0010630_abnormal_cardiac_muscle2.74794908
16MP0005620_abnormal_muscle_contractility2.64575231
17MP0006138_congestive_heart_failure2.62285060
18MP0000750_abnormal_muscle_regeneration2.60933580
19MP0004484_altered_response_of2.55641014
20MP0003828_pulmonary_edema2.44486952
21MP0002106_abnormal_muscle_physiology2.31380422
22MP0004130_abnormal_muscle_cell2.28539943
23MP0004085_abnormal_heartbeat2.28449187
24MP0002102_abnormal_ear_morphology2.22746568
25MP0002269_muscular_atrophy2.17550119
26MP0003221_abnormal_cardiomyocyte_apopto2.13783041
27MP0004510_myositis2.07249176
28MP0005369_muscle_phenotype1.85905424
29MP0002127_abnormal_cardiovascular_syste1.80044592
30MP0003136_yellow_coat_color1.78093133
31MP0000759_abnormal_skeletal_muscle1.75029731
32MP0006036_abnormal_mitochondrial_physio1.72581449
33MP0000747_muscle_weakness1.68402361
34MP0004145_abnormal_muscle_electrophysio1.65916954
35MP0003950_abnormal_plasma_membrane1.64196470
36MP0004233_abnormal_muscle_weight1.57309021
37MP0002735_abnormal_chemical_nociception1.47257949
38MP0003567_abnormal_fetal_cardiomyocyte1.37850377
39MP0005551_abnormal_eye_electrophysiolog1.37773936
40MP0005666_abnormal_adipose_tissue1.33701001
41MP0002332_abnormal_exercise_endurance1.33259641
42MP0005670_abnormal_white_adipose1.26617734
43MP0000343_altered_response_to1.23549071
44MP0000266_abnormal_heart_morphology1.19792664
45MP0010368_abnormal_lymphatic_system1.17740151
46MP0003279_aneurysm1.16861234
47MP0005165_increased_susceptibility_to1.12804650
48MP0006072_abnormal_retinal_apoptosis1.12312201
49MP0006276_abnormal_autonomic_nervous1.12028846
50MP0000372_irregular_coat_pigmentation1.12003977
51MP0002234_abnormal_pharynx_morphology1.08247241
52MP0003880_abnormal_central_pattern1.05676589
53MP0009745_abnormal_behavioral_response1.04589636
54MP0005253_abnormal_eye_physiology1.02828620
55MP0006035_abnormal_mitochondrial_morpho1.00539566
56MP0003787_abnormal_imprinting0.95762615
57MP0002638_abnormal_pupillary_reflex0.94277117
58MP0002272_abnormal_nervous_system0.91682664
59MP0008877_abnormal_DNA_methylation0.89901221
60MP0001984_abnormal_olfaction0.89799113
61MP0001529_abnormal_vocalization0.89258796
62MP0005375_adipose_tissue_phenotype0.86815479
63MP0004185_abnormal_adipocyte_glucose0.84825634
64MP0002128_abnormal_blood_circulation0.84811243
65MP0000230_abnormal_systemic_arterial0.84621215
66MP0005266_abnormal_metabolism0.80879611
67MP0001968_abnormal_touch/_nociception0.78411053
68MP0005623_abnormal_meninges_morphology0.78270642
69MP0005646_abnormal_pituitary_gland0.78101101
70MP0003566_abnormal_cell_adhesion0.78057333
71MP0004133_heterotaxia0.73758674
72MP0005451_abnormal_body_composition0.72714301
73MP0000427_abnormal_hair_cycle0.72128783
74MP0002254_reproductive_system_inflammat0.71917972
75MP0005171_absent_coat_pigmentation0.71706068
76MP0001970_abnormal_pain_threshold0.71429696
77MP0009046_muscle_twitch0.70223095
78MP0001485_abnormal_pinna_reflex0.70140033
79MP0002108_abnormal_muscle_morphology0.67852441
80MP0002909_abnormal_adrenal_gland0.66967161
81MP0001879_abnormal_lymphatic_vessel0.66126462
82MP0003806_abnormal_nucleotide_metabolis0.65749809
83MP0000767_abnormal_smooth_muscle0.65255299
84MP0002733_abnormal_thermal_nociception0.63216539
85MP0002736_abnormal_nociception_after0.61774671
86MP0002751_abnormal_autonomic_nervous0.61120198
87MP0003937_abnormal_limbs/digits/tail_de0.60667454
88MP0005503_abnormal_tendon_morphology0.60632137
89MP0003705_abnormal_hypodermis_morpholog0.60046705
90MP0001501_abnormal_sleep_pattern0.59574771
91MP0001486_abnormal_startle_reflex0.58199197
92MP0004043_abnormal_pH_regulation0.57070924
93MP0002572_abnormal_emotion/affect_behav0.55585373
94MP0004272_abnormal_basement_membrane0.54443765
95MP0002938_white_spotting0.54002170
96MP0001986_abnormal_taste_sensitivity0.53929243
97MP0002876_abnormal_thyroid_physiology0.52424073
98MP0002064_seizures0.51211275
99MP0005187_abnormal_penis_morphology0.49859586
100MP0002925_abnormal_cardiovascular_devel0.49254915
101MP0001661_extended_life_span0.48450176
102MP0003984_embryonic_growth_retardation0.47638421
103MP0004142_abnormal_muscle_tone0.47392426
104MP0005319_abnormal_enzyme/_coenzyme0.47187832
105MP0000003_abnormal_adipose_tissue0.46937858
106MP0005085_abnormal_gallbladder_physiolo0.46787731
107MP0002088_abnormal_embryonic_growth/wei0.46329546
108MP0002557_abnormal_social/conspecific_i0.46020761
109MP0008438_abnormal_cutaneous_collagen0.45657800
110MP0004885_abnormal_endolymph0.45036134
111MP0005195_abnormal_posterior_eye0.45001942
112MP0000538_abnormal_urinary_bladder0.44675504
113MP0004147_increased_porphyrin_level0.42772472
114MP0002752_abnormal_somatic_nervous0.41644249
115MP0002078_abnormal_glucose_homeostasis0.41062089
116MP0002063_abnormal_learning/memory/cond0.40729820
117MP0001614_abnormal_blood_vessel0.37950142
118MP0001784_abnormal_fluid_regulation0.36993272
119MP0002971_abnormal_brown_adipose0.36143609
120MP0000013_abnormal_adipose_tissue0.35582222
121MP0000733_abnormal_muscle_development0.35274642
122MP0009384_cardiac_valve_regurgitation0.33459420
123MP0005535_abnormal_body_temperature0.31511597
124MP0008961_abnormal_basal_metabolism0.30785695
125MP0005595_abnormal_vascular_smooth0.30522900
126MP0005386_behavior/neurological_phenoty0.30351598
127MP0004924_abnormal_behavior0.30351598
128MP0003948_abnormal_gas_homeostasis0.30129686
129MP0005275_abnormal_skin_tensile0.28820025
130MP0001727_abnormal_embryo_implantation0.27622819
131MP0002295_abnormal_pulmonary_circulatio0.26766729
132MP0005380_embryogenesis_phenotype0.26032644
133MP0001672_abnormal_embryogenesis/_devel0.26032644
134MP0009840_abnormal_foam_cell0.25914839
135MP0002822_catalepsy0.25791169
136MP0000249_abnormal_blood_vessel0.22604172
137MP0002133_abnormal_respiratory_system0.22471777
138MP0005388_respiratory_system_phenotype0.22471777
139MP0002118_abnormal_lipid_homeostasis0.21033440
140MP0005334_abnormal_fat_pad0.20212109
141MP0003195_calcinosis0.20039006
142MP0005083_abnormal_biliary_tract0.19754235
143MP0005167_abnormal_blood-brain_barrier0.19740821
144MP0001958_emphysema0.19013465
145MP0005332_abnormal_amino_acid0.18758978
146MP0005584_abnormal_enzyme/coenzyme_acti0.18195866

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)8.46892347
2Ventricular tachycardia (HP:0004756)7.48984132
3Atrial fibrillation (HP:0005110)6.69072581
4Primary atrial arrhythmia (HP:0001692)6.26105571
5Calf muscle hypertrophy (HP:0008981)6.25362144
6Supraventricular tachycardia (HP:0004755)6.06448448
7Supraventricular arrhythmia (HP:0005115)5.93981362
8Lipoatrophy (HP:0100578)5.74925987
9Muscle hypertrophy of the lower extremities (HP:0008968)5.56267797
10Exercise-induced muscle cramps (HP:0003710)5.41649149
11Muscle fiber splitting (HP:0003555)5.33860048
12Right ventricular cardiomyopathy (HP:0011663)5.29480755
13Abnormality of the calf musculature (HP:0001430)5.26611350
14Exercise-induced myalgia (HP:0003738)5.17536401
15Syncope (HP:0001279)5.13569788
16Abnormality of the left ventricular outflow tract (HP:0011103)5.13480203
17Subaortic stenosis (HP:0001682)5.13480203
18Bundle branch block (HP:0011710)4.93094052
19Hyporeflexia of lower limbs (HP:0002600)4.82897578
20Palpitations (HP:0001962)4.79863678
21Dilated cardiomyopathy (HP:0001644)4.73127580
22Prolonged QT interval (HP:0001657)4.61595387
23Myoglobinuria (HP:0002913)4.50446251
24Ventricular arrhythmia (HP:0004308)4.24975057
25Asymmetric septal hypertrophy (HP:0001670)4.12955181
26Heart block (HP:0012722)4.08658466
27EMG: myopathic abnormalities (HP:0003458)3.99247356
28Atrioventricular block (HP:0001678)3.94953194
29Ventricular fibrillation (HP:0001663)3.87675506
30Abnormal atrioventricular conduction (HP:0005150)3.85073955
31Increased connective tissue (HP:0009025)3.58316429
32Acute necrotizing encephalopathy (HP:0006965)3.42309408
33Rhabdomyolysis (HP:0003201)3.41080270
34Abnormal mitochondria in muscle tissue (HP:0008316)3.40634145
35Abnormal EKG (HP:0003115)3.32508173
36Hepatic necrosis (HP:0002605)3.29339699
37Left ventricular hypertrophy (HP:0001712)3.17133859
38Myotonia (HP:0002486)3.08128682
39Difficulty running (HP:0009046)2.96319008
40Bradycardia (HP:0001662)2.94979111
41Acute encephalopathy (HP:0006846)2.93187913
42Hepatocellular necrosis (HP:0001404)2.89186547
43Palmoplantar keratoderma (HP:0000982)2.86412772
44Ketoacidosis (HP:0001993)2.84463946
45Progressive macrocephaly (HP:0004481)2.83666726
46Mitochondrial inheritance (HP:0001427)2.77640416
47Hypoglycemic coma (HP:0001325)2.76597825
48Distal lower limb muscle weakness (HP:0009053)2.68410038
49Cerebral edema (HP:0002181)2.65455048
50Hypoplastic heart (HP:0001961)2.64998587
51Ragged-red muscle fibers (HP:0003200)2.64646363
52Congenital stationary night blindness (HP:0007642)2.63329010
53Increased CSF lactate (HP:0002490)2.60923435
54Difficulty climbing stairs (HP:0003551)2.59675557
55Conjunctival hamartoma (HP:0100780)2.52204185
56Dicarboxylic aciduria (HP:0003215)2.48662516
57Abnormality of dicarboxylic acid metabolism (HP:0010995)2.48662516
58Increased muscle lipid content (HP:0009058)2.48541785
59Abnormality of fatty-acid metabolism (HP:0004359)2.45756970
60Testicular atrophy (HP:0000029)2.42354658
61Pancreatic cysts (HP:0001737)2.41004275
62Pancreatic fibrosis (HP:0100732)2.33816541
63Limb-girdle muscle atrophy (HP:0003797)2.32382121
64Pheochromocytoma (HP:0002666)2.32143965
65Exercise intolerance (HP:0003546)2.31980796
66Areflexia of lower limbs (HP:0002522)2.30124556
67Respiratory failure (HP:0002878)2.29208621
68Attenuation of retinal blood vessels (HP:0007843)2.27892126
69Lactic acidosis (HP:0003128)2.27779112
70Molar tooth sign on MRI (HP:0002419)2.27318573
71Abnormality of midbrain morphology (HP:0002418)2.27318573
72Hyperventilation (HP:0002883)2.23524356
73Nephronophthisis (HP:0000090)2.23208335
74Abnormality of the renal cortex (HP:0011035)2.20738736
75Sudden cardiac death (HP:0001645)2.20690401
76Increased intramyocellular lipid droplets (HP:0012240)2.18689134
77True hermaphroditism (HP:0010459)2.15346595
78Congenital malformation of the right heart (HP:0011723)2.13368952
79Double outlet right ventricle (HP:0001719)2.13368952
80Renal cortical cysts (HP:0000803)2.12477267
81Abnormality of the foot musculature (HP:0001436)2.11958774
82Congestive heart failure (HP:0001635)2.10980383
83Neoplasm of the adrenal gland (HP:0100631)2.10926747
84Increased variability in muscle fiber diameter (HP:0003557)2.10911352
85Neuroendocrine neoplasm (HP:0100634)2.08815523
86Ketosis (HP:0001946)2.08392787
87Toxemia of pregnancy (HP:0100603)2.07197876
88Neck muscle weakness (HP:0000467)2.06515802
89Limb hypertonia (HP:0002509)2.05949283
90Patent foramen ovale (HP:0001655)2.04580851
91Hamartoma of the eye (HP:0010568)2.01417957
92Dysmetric saccades (HP:0000641)2.00510844
93Neoplasm of head and neck (HP:0012288)1.98499408
94Esophageal neoplasm (HP:0100751)1.98499408
95Muscle stiffness (HP:0003552)1.96194944
96Foot dorsiflexor weakness (HP:0009027)1.95490104
97Abnormal rod and cone electroretinograms (HP:0008323)1.94693921
98Hyperinsulinemic hypoglycemia (HP:0000825)1.94375640
99Tubular atrophy (HP:0000092)1.91321279
100Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.90578076
101Abnormality of alanine metabolism (HP:0010916)1.90578076
102Hyperalaninemia (HP:0003348)1.90578076
103Abnormality of the aortic arch (HP:0012303)1.90245299
104Abnormality of the renal medulla (HP:0100957)1.90040145
105Large for gestational age (HP:0001520)1.88633669
106Rimmed vacuoles (HP:0003805)1.85644933
107Increased serum pyruvate (HP:0003542)1.85569253
108Abnormality of glycolysis (HP:0004366)1.85569253
109Chronic hepatic failure (HP:0100626)1.84622072
110Distal lower limb amyotrophy (HP:0008944)1.83532676
111Generalized aminoaciduria (HP:0002909)1.83275648
112Abnormality of skeletal muscle fiber size (HP:0012084)1.83041428
113Medial flaring of the eyebrow (HP:0010747)1.82789859
114Lipid accumulation in hepatocytes (HP:0006561)1.81102610
115Hypoplastic left heart (HP:0004383)1.80362105
116EMG: neuropathic changes (HP:0003445)1.80256979
117Hip contracture (HP:0003273)1.79950058
118Mildly elevated creatine phosphokinase (HP:0008180)1.75982633
119Tinnitus (HP:0000360)1.75929034
120Polydipsia (HP:0001959)1.74897103
121Abnormal drinking behavior (HP:0030082)1.74897103
122Decreased central vision (HP:0007663)1.74776080
123Muscular dystrophy (HP:0003560)1.74531233
124Preauricular pit (HP:0004467)1.74294060
125Periauricular skin pits (HP:0100277)1.74294060
126Pulmonary artery stenosis (HP:0004415)1.73310989
127Aplasia/Hypoplasia of the fovea (HP:0008060)1.73296606
128Hypoplasia of the fovea (HP:0007750)1.73296606
129Lymphangioma (HP:0100764)1.73106259
130Central scotoma (HP:0000603)1.71754458
131Athetosis (HP:0002305)1.71298453
132Prominent supraorbital ridges (HP:0000336)1.68357632
133Gaze-evoked nystagmus (HP:0000640)1.68196824
134Type II lissencephaly (HP:0007260)1.67638105
135Steppage gait (HP:0003376)1.64354078
136Chorioretinal atrophy (HP:0000533)1.63797090
137Abnormality of macular pigmentation (HP:0008002)1.62636656
138Abnormality of the fovea (HP:0000493)1.59244383
139Focal motor seizures (HP:0011153)1.57479581
140Mesangial abnormality (HP:0001966)1.56405473
141Vitreoretinal degeneration (HP:0000655)1.55748762
142Optic disc pallor (HP:0000543)1.55149338
143Glycosuria (HP:0003076)1.52642016
144Abnormality of urine glucose concentration (HP:0011016)1.52642016
145Absent rod-and cone-mediated responses on ERG (HP:0007688)1.52498500
146Keratoconus (HP:0000563)1.51972433
147Increased corneal curvature (HP:0100692)1.51972433
148Abnormal connection of the cardiac segments (HP:0011545)1.51938045

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.85860053
2MYLK4.58191228
3FRK4.33660724
4LMTK24.32398987
5PHKG23.72449697
6PHKG13.72449697
7OBSCN3.72063546
8PDK43.33448014
9PDK33.33448014
10PKN23.19361984
11DMPK3.15161980
12MAP4K23.12392337
13BCKDK2.60810531
14TRIB32.55413596
15PIK3CA2.51531171
16MUSK2.48176917
17STK242.21602595
18TIE12.10294258
19NEK12.07579321
20ADRBK21.98978052
21PDK21.97145958
22WNK31.87605862
23PINK11.85968786
24TNIK1.81346819
25PAK31.68944524
26MARK11.68648002
27GRK71.60539320
28BMPR1B1.58039493
29NUAK11.50560789
30PRKD11.46202055
31CAMK2D1.44395935
32GRK11.41129558
33CASK1.39905701
34TAOK21.34796467
35CDC42BPA1.32655041
36MAPK131.28976089
37STK41.26536493
38ILK1.26447924
39STK38L1.26337174
40ZAK1.25387187
41MAP2K61.24403923
42WNK41.15044855
43EPHA41.13568221
44ROCK11.10000271
45TLK11.04272082
46DAPK31.01572629
47MAP3K50.95719674
48EPHA30.94354528
49INSRR0.93609088
50PKN10.91373206
51RIPK10.91310239
52MAPK120.89904043
53TRPM70.89697019
54FLT30.88574759
55MAPKAPK30.86005255
56PLK40.84143666
57PRKAA10.83976942
58CAMK40.83899841
59NTRK30.82985516
60MAP3K70.82553227
61PRKAA20.77678867
62STK380.75248871
63PDGFRA0.74442336
64CCNB10.72838632
65RPS6KL10.71749376
66RPS6KC10.71749376
67ROCK20.71567794
68CAMK2A0.67777598
69KDR0.66343945
70MAP3K30.66009866
71ITK0.65562091
72ACVR1B0.64954570
73WNK10.64950131
74RPS6KA60.61994328
75CAMK10.60934734
76PTK2B0.60893656
77PLK20.59542902
78NLK0.57600980
79NEK20.56912819
80MAP2K30.56675188
81MAP3K40.55775034
82NME20.55529867
83PRKCE0.54899071
84PRKACB0.54710884
85OXSR10.53589999
86TGFBR20.53086008
87DYRK20.47780238
88PNCK0.47199064
89MARK30.46307342
90STK390.46135918
91EPHB10.45991646
92PIK3CG0.45901898
93TAOK30.45332144
94BRSK20.44673540
95PRKACA0.42057562
96PRKACG0.41865202
97IRAK10.41711151
98TXK0.41597896
99PRKD30.41595377
100AKT30.41314822
101STK30.40244297
102ICK0.39719621
103STK110.38238088
104NTRK20.37166761
105MST40.36984257
106CSNK1G10.36353647
107ERBB30.36238363
108LIMK10.35564896
109CSNK1G20.35508584
110PRKCG0.35297575
111PDPK10.34685748
112PRKCH0.33953044
113PRKG20.32700758
114CAMK2G0.31180515
115AKT20.29122455
116RPS6KA10.28180239
117UHMK10.27791760
118PDK10.27347721
119RPS6KA50.26751892
120CAMK2B0.26554792
121EPHB20.26195468
122NEK90.25509800
123PTK60.25217020
124SIK10.24939958
125LATS20.23133198
126JAK10.20340029
127MTOR0.19627734
128FER0.19597364
129PRKG10.18937822
130LATS10.18014190
131SGK30.17873699
132RET0.17212629
133RPS6KA20.15802234
134RPS6KA30.11992141
135LRRK20.10981970
136SGK10.10428737
137PDGFRB0.10331817
138MAPKAPK20.10134332
139MAPK70.09369652
140PRKCQ0.08262773
141FGFR40.07124133
142ADRBK10.06704439
143MAP3K100.05390721
144MAP3K10.05022204
145TGFBR10.04655773
146JAK20.04271856
147PRKD20.04252685

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.90881881
2Cardiac muscle contraction_Homo sapiens_hsa042604.61669119
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.22949423
4Dilated cardiomyopathy_Homo sapiens_hsa054143.82259112
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.68948195
6Parkinsons disease_Homo sapiens_hsa050123.60084453
7Oxidative phosphorylation_Homo sapiens_hsa001903.54953655
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.29382537
9Propanoate metabolism_Homo sapiens_hsa006403.21688833
10Fatty acid degradation_Homo sapiens_hsa000712.80623152
11Alzheimers disease_Homo sapiens_hsa050102.63804231
12Carbon metabolism_Homo sapiens_hsa012002.47339657
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.40802829
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.31228689
15Huntingtons disease_Homo sapiens_hsa050162.30365482
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.25589905
17Fatty acid metabolism_Homo sapiens_hsa012122.11484169
18Phototransduction_Homo sapiens_hsa047441.93576564
19Pyruvate metabolism_Homo sapiens_hsa006201.79550224
20Viral myocarditis_Homo sapiens_hsa054161.77079078
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.76509169
22Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.75632246
23Linoleic acid metabolism_Homo sapiens_hsa005911.75494432
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.53036400
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.44283082
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.41683522
27Butanoate metabolism_Homo sapiens_hsa006501.38828959
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.30350673
29Fatty acid elongation_Homo sapiens_hsa000621.29972036
30Nitrogen metabolism_Homo sapiens_hsa009101.29903945
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29456820
32Olfactory transduction_Homo sapiens_hsa047401.26129625
33Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.24599316
34GABAergic synapse_Homo sapiens_hsa047271.19496430
35Morphine addiction_Homo sapiens_hsa050321.18965012
36Regulation of autophagy_Homo sapiens_hsa041401.18516516
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.17431407
38Salivary secretion_Homo sapiens_hsa049701.12678684
39Nicotine addiction_Homo sapiens_hsa050331.12509788
40Biosynthesis of amino acids_Homo sapiens_hsa012301.12407734
41PPAR signaling pathway_Homo sapiens_hsa033201.04141392
42cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97468277
43Insulin resistance_Homo sapiens_hsa049310.92740195
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89641279
45Ether lipid metabolism_Homo sapiens_hsa005650.89203232
46Glucagon signaling pathway_Homo sapiens_hsa049220.88875746
47Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86710441
48Adipocytokine signaling pathway_Homo sapiens_hsa049200.86413438
49Starch and sucrose metabolism_Homo sapiens_hsa005000.85300432
50Cocaine addiction_Homo sapiens_hsa050300.84640853
51Glutamatergic synapse_Homo sapiens_hsa047240.84250317
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.82559822
53Tryptophan metabolism_Homo sapiens_hsa003800.82253289
54Serotonergic synapse_Homo sapiens_hsa047260.80259469
55Lysine degradation_Homo sapiens_hsa003100.78129765
56Basal transcription factors_Homo sapiens_hsa030220.78074390
57Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.77848381
58Mineral absorption_Homo sapiens_hsa049780.73868046
59Insulin signaling pathway_Homo sapiens_hsa049100.73048217
60Amphetamine addiction_Homo sapiens_hsa050310.72321690
61Selenocompound metabolism_Homo sapiens_hsa004500.71163919
62Arginine biosynthesis_Homo sapiens_hsa002200.70399628
63HIF-1 signaling pathway_Homo sapiens_hsa040660.68984978
64beta-Alanine metabolism_Homo sapiens_hsa004100.68711938
65Calcium signaling pathway_Homo sapiens_hsa040200.65520449
66Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65152667
67Protein digestion and absorption_Homo sapiens_hsa049740.65058817
68Type II diabetes mellitus_Homo sapiens_hsa049300.63701634
69Fanconi anemia pathway_Homo sapiens_hsa034600.63235192
70Focal adhesion_Homo sapiens_hsa045100.63008911
71Arginine and proline metabolism_Homo sapiens_hsa003300.60423288
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.60293915
73Histidine metabolism_Homo sapiens_hsa003400.58604347
74Primary bile acid biosynthesis_Homo sapiens_hsa001200.58355779
75Dopaminergic synapse_Homo sapiens_hsa047280.57856197
76AMPK signaling pathway_Homo sapiens_hsa041520.54712130
77Galactose metabolism_Homo sapiens_hsa000520.54000100
78Phenylalanine metabolism_Homo sapiens_hsa003600.53097660
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.53021696
80Peroxisome_Homo sapiens_hsa041460.52791709
81Arachidonic acid metabolism_Homo sapiens_hsa005900.51414702
82Caffeine metabolism_Homo sapiens_hsa002320.50758285
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50394604
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.47318914
85ABC transporters_Homo sapiens_hsa020100.47278569
86Oxytocin signaling pathway_Homo sapiens_hsa049210.46746800
87Central carbon metabolism in cancer_Homo sapiens_hsa052300.46463188
88Tight junction_Homo sapiens_hsa045300.46411755
89Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45972062
90Maturity onset diabetes of the young_Homo sapiens_hsa049500.45438342
91Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.45303100
92Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43126186
93Fatty acid biosynthesis_Homo sapiens_hsa000610.42398285
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41056910
95Fructose and mannose metabolism_Homo sapiens_hsa000510.40825943
96cAMP signaling pathway_Homo sapiens_hsa040240.40637758
97TGF-beta signaling pathway_Homo sapiens_hsa043500.40519951
98ECM-receptor interaction_Homo sapiens_hsa045120.40510619
99RNA degradation_Homo sapiens_hsa030180.39938686
100Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38879114
101Renin secretion_Homo sapiens_hsa049240.36680469
102Asthma_Homo sapiens_hsa053100.36642513
103Retinol metabolism_Homo sapiens_hsa008300.35274091
104Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33750367
105Insulin secretion_Homo sapiens_hsa049110.31788052
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31422580
107Chemical carcinogenesis_Homo sapiens_hsa052040.30728074
108Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.29823929
109Metabolic pathways_Homo sapiens_hsa011000.29497479
110Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.29270630
111Adherens junction_Homo sapiens_hsa045200.28269993
112Gastric acid secretion_Homo sapiens_hsa049710.27685199
113Homologous recombination_Homo sapiens_hsa034400.26393320
114Amoebiasis_Homo sapiens_hsa051460.23702712
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.23349227
116Circadian entrainment_Homo sapiens_hsa047130.22756916
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.21305160
118Aldosterone synthesis and secretion_Homo sapiens_hsa049250.20186675
119Tyrosine metabolism_Homo sapiens_hsa003500.16204578
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.15322850
121Fat digestion and absorption_Homo sapiens_hsa049750.14514198
122Leukocyte transendothelial migration_Homo sapiens_hsa046700.13272220
123Renal cell carcinoma_Homo sapiens_hsa052110.12765184
124Ovarian steroidogenesis_Homo sapiens_hsa049130.12115460
125Proteoglycans in cancer_Homo sapiens_hsa052050.10149232
126Gap junction_Homo sapiens_hsa045400.09410928
127Circadian rhythm_Homo sapiens_hsa047100.08501619
128Platelet activation_Homo sapiens_hsa046110.07918885
129Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.07897455
130Taste transduction_Homo sapiens_hsa047420.07043268
131Dorso-ventral axis formation_Homo sapiens_hsa043200.06876197
132Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.05332930
133Pancreatic secretion_Homo sapiens_hsa049720.05025211
134Bile secretion_Homo sapiens_hsa049760.04874247
135Cholinergic synapse_Homo sapiens_hsa047250.03504288
136VEGF signaling pathway_Homo sapiens_hsa043700.03251784
137GnRH signaling pathway_Homo sapiens_hsa049120.02065645
138Notch signaling pathway_Homo sapiens_hsa043300.00921828
139Small cell lung cancer_Homo sapiens_hsa052220.00747273
140Toxoplasmosis_Homo sapiens_hsa051450.00437292
141mTOR signaling pathway_Homo sapiens_hsa041500.00170161
142Glycerolipid metabolism_Homo sapiens_hsa005610.00088018
143FoxO signaling pathway_Homo sapiens_hsa04068-0.0537813
144PI3K-Akt signaling pathway_Homo sapiens_hsa04151-0.0330135
145Estrogen signaling pathway_Homo sapiens_hsa04915-0.0324153
146AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933-0.0125937

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